Arnica montana
autorstwa Richard Hughes & Jabez P. Dake — A Cyclopaedia of Drug Pathogenesy
Volume I — Main text
ARNICA. Arnica montdna^ L. Leopard^s bane. Nat. Ord., ComposUa.
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Provings. i. Hahnemann, Fragmenta de Viribus Medicament forum positivis. Contains 117 symptoms from self and 33 from authors.
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Ibid., Mat. Med. Pura^ vol. i of original and translation. Contains 591 symptoms from self and 9 others, and 47 from authors.
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a.\ AssMANN, on Feb. 26th, 1823, at 5 p.m., drank 2 oz. of infusion (= 7 grs.). In spite of careful filtration it caused considerable scraping sensation in mouth and gullet. Constrictive pains in stomach
• " Graves observes that when given to persons affected with various diseases, it occasions vertigo and headache.** (Still£, op. cit.)
t Throughout Jore's provings of this plant {a) will denote preparations of flowers, (b) of root. Hahnemann's provings were mostly made with the tincture of the dry root. — Eds.
then came on, lasting i h., and then decreasing gradually in severity. When these had somewhat abated, head became confused and there was dull pressing headache under parietals and in neighbourhood of lachrymal fossa. This ceased during n. after increased perspiration* On following d, there remained general lassitude, heaviness of head^ and inability to work long or hard. March 3rd, 1823, 5 p.m,, after 4 oz. of infusion (= 22 grs.) experienced all above symptoms but less markedly. A new effect of larger dose was that at g.30 p.m* diarrhoeic evacuations took place with slight cutting pains in bowels , this was repeated thrice at short intervals next m.
h. On March 8th, 1823, at 6 p.m., took 6 drops of tincture* mixed with i oz* water. Repeated belchings followed immediately ; 15 m. later tympanitic distension of abdomen followed by severe cutting pains in belly which increased until 9 p,m. and only ceased during n. During e, had repeated foul -smelling eructations but without relief to other symptoms. Same effects followed doses of t2 drops on 10th and of 24 drops on 14th. After 62 drops on 1 7th felt very soon pressure at stomach with feeling as if xiphoid process was being pressed in, stabbing under sternum, vertigo, pressing headache in parietal bones and in orbits, palpitation, and quickened pulse. These symptoms lasted all e., disturbed sleep considerably, and lasted with varying seventy till a.m. on 19th (? i8th); bowels meanwhile sluggish, hunger increased, although appetite was considerably diminished. Same results followed dose of 84 drops on 1 9th. (JuRg^s Matir, ilu €in. Kunn. HcilmhttiUhre^ 1825.)
- a, Engler, on Feb. f 7th at 5 p.m., took 4 oz. of infusion (= 7 grs.), and felt after l h. pulse somewhat slower and irregular; during following n. was restless and often disturbed by dreams. 24th.^ — After 4 oz. (= 15 grs.) noticed immediately burning scraping in oral cavity and gullet, repeated belchings, and during e. irregular pulse. Following n. was restless. Next m. on rising noticed peculiar painful feeling down back similar to that caused by continued stooping over hard work, but lasting only \ h. Half h. after similar dose next d. superficial pressive pain between shoulders set in and lasted nearly 3 h. Same pain was experienced next d. after similar dose, but affecting more r. subscapular region and lasting nearly 4 h. March 5th, 6 p.m., took 4 oz, (= 30 grs.). Scraping in gullet more marked, and in 10 m, pressive pain between shoulder-blades, proceeding apparently from posterior wall of stomach, made itself felt, and disappeared only next m. During n. was restless and had lively dreams. {Ibid,)
h. Took from 6 to 36 drops of tinct. of root without result*
5, a, Heisterbergk (Feb. 17th, 5 p.m.) took 8 oz. infusion(=: 15 grs.) ; after 10 m, noticed pain in region of stomach ; this increased by degrees and lasted nearly i h. ; judged by feeling it seemed as if walls of stomach were drawn spasmodically together. Pulse 75 to 80. On 24th after similar dose noticed nothing but considerable distension of abdomen, which came on a few m. after dose, and lasted nearly an h. On following d. (25th) after similar dose same symptom was present and lasted nearly i h. When this had disappeared heaviness and con-
• Prepared from arnica root one part, rectified spirit (80 deg.) six parts.
fusion of head came on to moderate extent, lasting about 2 h. On 26th, 15 m. after taking 4 oz. (= 22 grs.) noticed moderate sensation of cramp in stomach lasting about 8 m., i h. after dose confusion of head also came on but only lasted i h. {Ibid,)
b. Took from 6 to 65 drops of tinct. without any but local effects.
- a, Kneschice on Feb. 22nd took 4 oz. of infusion (=15 grs.), and whilst swallowing dose noticed peculiar scraping burning sensation in mouth and gullet followed in few m. by heavy pressure in region of stomach ; former lasted 30 m., latter i h. On Mar. 3rd after dose made from 22 grs. experienced same effects. After quiet n. awoke next m. with severe stabbing pains in forehead and occiput, lasting all d. In addition, appetite was poor, bowels sluggish, and mental faculties impaired. Next d. after good n. rest felt quite well. Repeated same dose on 7th and noticed immediately above-mentioned scraping in throat, soon accompanied by considerable pressure in region of stomach ; former lasted only \ h., latter continued nearly 2 h., and during last h. stabbing pain in forehead and region of temples came on and did not leave him all e.
b. June 29th, 8 a.m., took \ oz. of infusion ( = 5 grs.) (experiments with tinct. having proved as fruitless as Heisterbergk's) \ after 15 m. fulness of stomach came on accompanied by slight pressure in upper and anterior part of stomach, lasting till 1 1 ; from 1 1 till 3 felt strong pressure in 1. side of cesophagus, pointing upwards, and accompanied at times with rather severe stabbing. At mid-day had no appetite. From i till 4 head became confused, had frequent inclination to sleep and felt disinclined for continuous exertion. Effects of drug seemed to have disappeared by e. June 30th, 8 a.m., repeated dose, shortly after taking which stomach felt full and remained in same condition until after i o ; pressure in oesophagus in same spot returned shortly before 12 and lasted about 2 h. Confusion of head coupled with inclination to sleep and disinclination for all active exertion lasted whole afternoon \ these attacks passed off at 5 p.m. {Ibid.)
- £7. Seyffert, after dessertspoonful of infusion taken at 5, 8, and II a.m. and at 2, 5, 8, and 11 p.m., noticed each time frequent belching, scraping in throat, drawing in region of stomach, and lasting confusion of head \ also frequent micturition^ colour of urine being normal. Repetition of experiment produced same symptoms, and in addition an indescribable malaise and disinclination for work.
b. After doses of tinct. varying from 20 to 60 drops taken in an oz. of water suffered from scraping in the throat, repeated belchings, confusion of head and frequent evacuation of flatus during the e. {Ibid,)
- a. Strofer on Feb. 17th at 4 p.m. took 4 oz. of infusion ( = 7 grs.). Burning scraping in throat came on at once, accompanied \ h. later by nausea ; vomiting could, however, be avoided. On 21st repeated dose and besides above effects noticed increased secretion of saliva, troublesome unpleasant pains in region of stomach, frontal headache lasting about 2 h. and only vanishing finally after supper. March 3rd, 6 p.m., took 4 oz. of infusion (= 22 grs.), and experienced symptoms of former doses, but much more acutely, especially secretion of saliva, nausea terminating in vomiting, rush of blood to head, and frontal
headache ; from this as from previous doses found arterial pulse stronger than usual. {Ii>td,)
b. Strofer's trial of tinct. of root was fruitless as that of others.
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a. Winkler on Feb. 25th, at 6 p,m,, took 4 oz. inf. and immediately after swallowing noticed severe burning in throat, gradually descending through oesophagus to stomach, lasting in mouth and guUct I h. In stomach this burning changed into pinching and pressing, and continued through small intestines as constrictive pain, accompanied with much movement* Abdomen became distended, almost tympanitic ; this was relieved by walk in open air. Towards 8 p.m. a notable change took place in the abdominal symptoms ; there remained at this time sensation of gnawing hunger, although all desire for food was wanting and W — had dined at 5 p,m. This hunger lasted whole e, and was still troublesome when W — fell asleep towards midnight. On awaking in m. was suffering from severe headache, which increased to such an extent that he nearly fell down from giddiness on going out into open air at 8 a.m. Headache ceased at 10 a.m., but nausea ana lassitude lasted till mid -day. {I hid.)
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a, GuNTZ. June 24th, 1824,8 a.m., aftter \ oz. felt immediately in throat and oesophagus (especially in anterior walls) a scraping lasting 5 m. ; plentiful secretion of thin saliva, and nausea, but without going on to vomiting ; 10 m. after dose pressure in stomach came on, increasing gradually to cramp- like pains and lasting nearly 2 h. ; these pains diminished after a meal of bread and milk at 10 a.m. On 25th, 8 a.m., took 2 oz. (= 20 grs.) ; scraping in throat and increased secretion of saliva followed, but to a smaller extent ; 15 m. after dose cramp in stomach came on, and continued for 2 h, ; after this frontal pain set in, lasting about an h. \ during afternoon colicky pains in abdomen occurred from time to time but without any evacuation of bowels j during n, slept very little because of a violent attack of bleeding from the nose. 3 oz. of infusion {= 30 grs.) 26th, and 3j of* 27th, produced same eiFects.
h, July 2nd, 8 am., after taking tincture and smaller doses of infusion without result, took 3 oz. of infusion ( = i drachm) and felt soon after dose slight scraping along gullet. 3 p.m, perceived transient stitch in umbilical region which appeared to have its seat in small intestines, and lasted { h, 3rd, 8 a.m., took 4 oz. (ss i drachm) i after \ h. dull pain came on in frontal region and lasted until towards c. ; at 6 next m. was attacked by pressing pain in r* hypochondriac region, which came and went, appearing to have its seat in liver or duodenum, and vanished at noon. [Ibid,)
9, a, JoRG, after doses varying from 3 to 20 grs.j obtained following results : Peculiar slight burning or scraping biting in throat extending through oesophagus to stomach, somewhat like heartburn, and lasting ^ to i h. Soon after repeated belch ings, at first with taste of drug, accumulation of saliva in mouth, and inclination to vomit without nausea, accompanied by feeling as if pharynx were swollen and prevented swallowing ; these three symptoms vanish and reappear several times during next few h. About i h* after taking drug cramp-like constrictive pain begins in stomach, causing pain generally, but mostJy in
posterior wall of stomach, as if this were being pressed against spinal column and as if latter were made sore at same time above and below situation of stomach. Two or three h, after dose slight cutting pain in small intestines comes on, followed in ^ b. or i h» by distension and swelling of small intestines with frequent urging to stool, relieved at times by diarrhoeic evacuations, at other times by passage of small and tough feces with much wind. Final effects arc pressure in head, confusion of same, usually one-sided rheumatic headache, and vertigo^ lasting I to 3, 4, or even 5 h. Pain at stomach frequently changes, after i, 2, or 3 h., into ravenous hunger, although appetite and digestion remain diminished.
b. June 30th, 8 a.m., after ^ii of infusion (== 2^ grs.) felt slight fulness in stomach and slight belching up of flatus, followed at 1 1 by slight dulness in head, which resolved itself at mid-day into general weariness, lassitude, and somnolence ; although these passed off after dinner, felt between 3 and 6 p,m, fatigued and disinclined for mental exertion. July ist, 10 a.m., took | oz. of infusion (= 5 grs.) ; felt immediately some scraping in throat, later on fulness of stomach and distension of abdomen, with frequent passage of flatus and urging to stool, although more constipated than usual 5 3 to 6 p.m., again felt confusion of head and distaste to work. Next m. at 5 a.m. on sitting down to my work-table was surprised by severe pain in spinal column, such as would be felt by suddenly standing upright after long stooping : this cramp-like pain was not situate in the muscles of the back, but in the inner soft parts of spinal column, appearing at times as if posterior wall of stomach were pressed forcibly against anterior surface of spine. Two h* later pain was concentrated more in upper part of spinal column, between shoulder-blades ; by mid-dayall effects had passed off. On repeating dose 2 d, later same symptoms were produced, pain in spinal column lasting this time 2 h. and proceeding apparently from stomach, {Ibid,)
- b, Frau Ch. took \ oz. (s= 2| grs.) ; no scraping was produced, but moderate burning feeling in throat, less nausea and sinking, more pressure at stomach than from infusion of flowers. With this pres* sure at stomach was coupled at times feeling of emptiness and ravenous hunger, although there was complete loss of appetite and disinclination for all food. In afternoon she suffered from pressive headache, especially in forehead. Pressure at stomach was repeated from time to time, accompanied by unpleasant feeling of fulness, although stomach was empty, and also frequent acrid feeling in oral cavity lasting till 3rd d. after taking drug. {Ibid.)
Ji. b, L — after similar dose noticed no symptoms in digestive tract, but from 11 a.m. till 10 p.m. felt confusion of head with frequently recurring inclination to sleep and distaste for active exertion. (Ibid.)
12* Eight members of the Vienna Society of Physicians proved A. in form of ext. of flowers, of which gr. j — xij were taken daily. Phenomena observed from its use were ;
a. In digestive organic fly»*ig pains in abdomen, epigastrium, and r. hypochondrium ; eructation, disgust, yawning j dryness of mouth and throat ; burning of tongue and palate ; oppression of stomach ; increased appetite j flatulence j firmer and less frequent evacuations.
ill $fnce childhood, except year ago. Always took the
b. In vascular iystgm^ stronger beat of heart ; frequent blowing of lose with traces of blood ; slight epistaxis i swelling of hiemorrhoidal Ivessels,
r. In nervous system^ confusion and fulness of head i slight pressure ; partial headache ; vision of sparks ; itching of skin and eyes ; comfortable feeling or exhaustion ; restless sleep, vivid agreeable dreams. {fViimr Zeitichr^y Dec., 1844,)
- ScHNELLER, one of the above, reports that he took doses increasing by j gr, daily for 1 1 d,, in which therefore he took 78 grs. Up to dose of 6 grs* nothing particular was noticed save a bitter, rather
"disgusting taste, and increased flatus; sleep was also diminished and frather restless. Symptoms produced by doses of 7 — 10 grs* were, besides the foregoing, sensation of burning in tongue and soft palate^ as if from pepper or from swallowing a hot liquid, which set in particularly 3 h, after taking medicine and was confined to ant. third of tongue, on which nothing abnormal was visible ; appetite unaffected. During doses of 1 1 and 12 grs, burning diminished and was only felt on point of tongue i in middle of lower lip several vesicles appeared containing a clear fluid ,and soon drying into scabs. In e. slight cpistaxis. Nights restless, ireams very vivid. (Uid^ March, 1846.)
- A. von SzoNTAGH, a*t. 31, never ague 10 years ago, and whooping-cough i , _ medicine about 1 1 a.m. either on sugar or mixed with water. Observed himself carefully for several weeks before proving.
a. From Oct, 20th took daily 3 drops of 3X. For some days pain in r, side of neck where the external carotid comes from under sternocleido-mastoideus muscle, as if a lymphatic gland were swollen there. The pain is distinctly felt on suddenly turning head to 1., on applying strong pressure on the spot, and when the carotids beat more strongly. This pain never felt before the proving, and since then has frequently recurred during the last 10 or 11 months. — 22nd and 23rd. On blowing nose in m. some drops of bright blood came from nose. — 24th. Unusually sleepy in forenoon.
b. From 24th I drop daily of ^. — 2Sth. Afternoon when sitting, light cracking and feeling of sprain in r. wrist on moving hand.^ — 24tli
r^nd 25th. Unusually early waking in m. with inability to go to sleep again, — 26th. 3 dropsy; nothing unusual. — 28th. 5 drops 0. In afternoon some violent stitches in glans penis. — 29th. Several times aching pain in first phalanges or 3 last fingers of 1. hand. All afternoon confusion of head with slight singing in r, ear ; e., aching pain in 1. eye extending to 1. half of forehead, followed by eructation and inclination to vomit.^ — joth. Slight singing all d. in r. ear* and similar but slighter headache
ron r. side without nausea. — 31st. 10 drops ^. Betore taking it frequent empty eructation. 2nd Nov., 15 drops ^. Before taking it toothache in a sound I, lower molar* After taking it frequent eructation of air, smelling of arnica. Afternoon, slight squeezing pain in lower angle of I. scapula. E.Jn larynx feeling of obstruction, like swelling, inclining him to cough and hawk, which sometimes brings away some thick phlegm but without relief — 4th, On waking confusion of head, in the '^rcnoon passing into pressive r, side headache. At 1 1 ani. 20 drops ip.
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After i h. urgent call to urinate and evacuation of a large quantity of watery urine. Headache lasts with intermissions all the afternoon, — 5th. Afternoon, suddenly a violent tearing and burning in outer border of 1. foot for I m. — 6ih* 30 drops ^. After 1 4 h. pressive squeezing pain in inner half of r. eyeball, going off gradually when walking in open air. The afternoon urine has a darker colour, acid reaction, and higher sp. gr» than usual. This and next day uncommonly frequent noises in ears, even when quite quiet. — 8th. 4.0 drops ^. Twitching pain in K side of chest for some m,, recurring later, — 9th. Forenoon, while walking for some m., each time he raised his 1. foot, and also when moving 1. ankle-joint, but not when moving knee, a creeping sensation in outer half of 1, sole, as if a nerve were pinched. From forenoon till e. similar l.-sided headache as on the 29th. The I. eye seemed more prominent and sensitive to pressure. ^ — loch. On waking and rising pressive pain in inner half of r. eyeball and corresponding part of forehead, going off towards noon. The creeping sensation in 1. sole came on under the same circumstances and at the same time as yesterday, lasted longer and occurred also in afternoon sometimes. At 1 x a.m. 50 drops 0. Towards e. in distal phalanx of r. ring finger when pressed acute pain as after a bruise for more than i h. Slight singing in r. ear when at rest all d. The urine passed between 2 and 6 p.m. is dark yellow, very acid, of high sp, gr., becomes opalescent wher boiled, but clear on adding nitr, ac. I The unboiled urine left to stand forms next day a slight sediment which f continually gets thicker, and after 62 h. when it is fetid shows many crystals of triple phosphates or urates under microscope. The urine passed before and after this is normal. — ^iith. Wakes early. In the n. and m, passes much odourless flatus. In m. in bed when lying on back tension in region of stomach. The sensitiveness to pressure of the phalanx of the r, ring finger recurs several times in the forenoon I and afternoon, but slighter and shorter, and in e, turns into tiresome aching pain, — 12th. 60 drops ^. The urine, except in m., when it is normal, shows the same characters as on the loth, — 13th. In afternoon for I h, pressive squeezing pain limited to the inner half of r. eyebalL The urine passed in forenoon is sulphur yellow, turbid, very frothy, , reaction neutral, and on standing a short time deposits a thick sediment, 'When boiled becomes still more turbid, but is cleared by nitr. ac, but becomes again turbid on the addition of ammonia. Left to stand it becomes fetid on the 3rd d. and deposits a large quantity of triple phoskphates. — 14th. All d. striking decrease of quantity of urine without increase of its sp. gr. In the forenoon urine the phosphates, in the afternoon urine the urates, were somewhat increased.-— '15th, 75 drops ^. E., suddenly a violent pressive tearing pain on ulnar side of distal phalanx of r. ring finger for some m. At n, when asleep breathes with open mouth (contrary to custom), whereby his mouth becomes quite dry. Urine in forenoon as on loth, afterwards as on 13th, then normal. — 16th, Afternoon and e,, transient tension in 1. buttock and knee* Towards e. till n. drawing and tearing in r, ring finger, especially in distal phalanx, sometimes also in little finger and along ulnar border of forearm. In the forenoon and afternoon urine the phosphates are sometimes more^ sometimes less, but always increased, E., unne normal, —
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1 7th. Urine as yesterday, — 18th. 100 drops ^. When swallowing, grea^ burning in throaty which goes ofF after i h. Afternoon ^unusually cheerful* Towards e. pressure and tension in spinal process of last cervical and first dorsal vertebras for a short time. Little sexual appetite* The urine passed from 3 to 6 p.m. very acid, turbid, deposits on standing a copious, brownish sediment ; after standing longer there appear in te single lumps, which show under microscope many cells* After 3 d. it becomes fetid, but is still acid, the sediment more a kind of turbidity i when boiled the turbidity increases and settles at the bottom of the tube. On adding z drops nit. ac. it is completely dissolved with evolution of gas. — 19th, Stool thinnerand darker than usual. A small rapidly suppurating acne-pustule forms under the r. angle of mouth with burning pain. The urine passed in m. and after breakfast normal ; that passed in forenoon and afternoon turbid* — 20th. Afternoon, violent twitching pain from 1. shoulder-joint to middle finger. — 21st. In m.on waking, violent drawing tearing pain on ulnar side of back of r. hand for some m. This pain recurs noon, afternoon, and e. — 23rd. In m, when walking, tearing pain in r. hip, ankle, and dorsum of foot. Later, when at rest, tearing jerking pain on ulnar side of back of L hand.— 24th. All day, pressive headache in r. eye, forehead, and temple. — 25th. In m. in bed, drawing pain in skin of back of L little finger* Soon afterwards pressive pain in joints of r. ring and little fingers. Afternoon, r.-sided headache. The forenoon urine turbid when passed. — ^26 th. Early in bed, drawing in skin of 1. little finger. — 24th, 25th, 26th. The above- described creeping in 1. sole when walking. Next d., drawing pains in limited places of the hands and r. foot, soon going ofF, — 30th. All d. the well-known I. -sided headache i on 1st Dec. the same pain on r, side, (A^. Zeitsch, f, horn, KUnik^ vii, 9, 20.)
15, We must beware of giving to irritable stomachs powerful doses of the flowers, because they produce painful sensations. I made the experiment twice. I took in succession three glasses of a warm infusion of 10 grs, : I soon felt a painful sensation of twitching at the stomach, which extended to the throat and lasted ^ h. (Rademacher, Erfahrungsheillehre^ 4th ed., I, 844.)
r6. On Sept. 30th, 1873, a student in pharmacy took, at 4 p.m., 18 grammes of tincture. In 5 m. his pulse had fallen from 70 to 64 ; at first irregular, it soon became thready and hardly palpable, The patient experienced an intolerable pr^ccordial anguish, it seemed to him as if the heart stopped and would not go on again j the hand applied over the heart felt its beats feeble and intermittent. The face grew pale, and there came on all of a sudden a great muscular debility so that the knees gave way ; it required a strong effort of will to resist the tendency to sit down. There were fibrillary contractions in several isolated bundles of muscular fibre, especially about the jaws, and a sort of contraction in the temples. Following with the finger the spinous processes downwards, pressure caused no sensation in the cervical region ; but as the finger descended to the dorsal vertebrae, it provoked a sharp and sudden uneasiness with some involuntary startings in the muscles of the nucha and back,^ — ^the head being drawn back, while the
trunk was kept erect. At the level of the last dorsal, the distress caused by pressure was so great that the patient shrank as we noticed him. He described the pain as extending like a girdle round as far as the epigastrium ; and causing a stifled feeling, as if a weight were on the chest. These somewhat alarming symptoms did not continue for more than 20 m. At 4.30 there remained only great weakness, depression, pallor, feeling of emptiness in head, a little tremor of hands, some nausea, and great desire to sleep. In this state he continued till e. ; at 10 p.m. pulse was still feeble and irregular, temp. 36*6.° The n. was fair; and all ended next d. in some diarrhoeic stools with flatulence. (Guillemot, Stude sur Us propriet^s phys, et ther, de P arnica^ Paris, 1874.)
- 7.45 a.m., health good, pulse 65, took 20 drops ix in water. Soon after, itching of 1. outer thigh and foot, followed by aching in same lee. 7.SS> itching of face and ears, afterwards in lower leg ; ache in 1. scapula and acromion. 8.3, slight headache in 1. parietal region ; itching returns. 8.5, eructations \ itching and soreness of chest walls. 8.6, aching in 1. wrist and palm, with itching ; slight vertigo while at rest, repeated soon after. 8.15, slight soreness of throat; eructations; shoulder lame. 8.25, pinching in splenic region; aching of right knee ; vertigo. 8.30, muscles of neck lame ; eructations ; itching in various parts ; feel stretchy. 9, gurgling in bowels; backache. 9.10, irritative cough ; pain in 1. tempor^ region. 9.15, urging to stool before usual hour; hands feel swollen and sore ; occasional sneezing. 9.20, no appetite ; eating causes urging to stool, with colic ; scant urine attends. 9.45, face flushed and swollen ; pulse 80. 10, sweat on hct ; yawning and stretching; much itching in various parts ; slight cough occasionally. 12.45 p.m., sexual excitement without cause ; feel very weary, with headache and sweat on forehead. 2, sun's heat makes me faint and nauseated (temp. 82°) ; pulse 94 before eating ; no appetite for lunch. 4, profuse sweat ; backache and languor, attended by dull headache. 4.20, urging to 8tool ; pulse 90. 5.30, scant urine ; rheumatic pains in shoulders ; irritative cough ; larynx very sore ; usual tobacco causes nausea. 7, colic and tenesmus after light meal ; legs and feet ache and are sore when walking ; easy sweats ; painful pimple on margin of beard (new). 10, extreme fatigue on retiring ; restlessness and wakefulness until midnight. 2nd d., waked with itching as of fleabites ; great debility until after eating ; dull headache during a.m. Symptoms in less degree continued for three following d. (Dr. A. W. Woodward, MS. Communication,)
II. Poisonings. — i. A workman in full health swallowed at one draught an enormous quantity of the tincture. He was seized immediately with violent burning at the stomach, then with colic ; he died 38 h. later, without presenting other noteworthy symptoms. At the autopsy there were marked traces of gastro-enteritis. (Wilms, Berliner Centralblatt f. d. med. tVissenschaften^ Nov., 1874.)
- A man of thirty swallowed by mistake 15 grammes of tinct. About 20 m. after he experienced violent headache, vertigo, nausea, vomiting \ these lasted for 1 h., at end of which came somnolence and
at last deep sleep for ii h. He was not perfectly restored till 7 d, later. (Ferrand, 7<?wrw. de Chimh Med,^ Sept,, 1869.)
3, a, A man of lymphatic constitution and sedentary habits, very susceptible to the influence of A., had been making an opodeldoc thereof ** I went to bed/' he states, " languid and exhausted ; sleep was much disturbed, and I awoke six or seven times, each time from dreaming that I was dying, and that my bed was surrounded by my friends, assembled to take their last leave of me. On following d. I had intense headache, accompanied with feeling of great weight and heaviness in cytSy and sensation of oppression and drooping in eyelids, as if they could not be raised. The L wrist was powerless for i h,, with feeling generally that I could not use my arms* I had sensation of oppressive weight at upper part of chest, with feeling of constriction in throat. In walking, I was feeble, as if suddenly grown old. My subsequent sensations were — a want of power in both ankles, with feeling of heavy weight on each instep j in the throat as it were the sound of a subdued whistle i feeling in upper part of head as though brains were sore and tender ; total want of appetite for 10 d., during which I loathed the very sight of food ; constant dry cough, shaking whole frame ; feeling as ( bruised over whole body ; nates felt hard, and there was swelling and tenderness in them ; thighs of a livid colour, with blue and yellowish marks as in a ' black and blue eye/ There was also sense of great weight across lower part of loins, and feeling of being drawn in as by a tight cord, I had all the while a longing desire to be m the free open air of the country.'*
h. During first 2 or 3 d, there were ever and anon a few patches on face, and especially on forehead, disappearing and recurring, resemblinj the A. rash. There was also some coryza. After a few d. larynx an trachea became affected, and he had a dry, short and hacking cough. Chest then became affected ; he had pains over thorax, stitches with cough, which increased pain ; a great deal of hypochondriacal anxiety j there was great tightness of chest, with difficulty of respiration. (He had only had camphor and ignatia up to this time, but now took phosphorus.) After suffering with these symptoms for about a fort* night he was one night overtaken with great distress about heart, stitches there, faintness, feeble, hurried, and irregular pulse, horror of instant death. Aconite and arsenicum were given to him, and he soon after went into the country.
c. It was fully a month from the commencement of his sufferings from A . before he was delivered from the medicinal disease. The ejects on mind and disposition were no less remarkable than those on the body. The patient is naturally cheerful, kindly, genial ; but throughout this illness he was downcast, waspish, and peevish* He is naturally of keen sensitiveness, and this was greatly exasperated. He had more or less hypochondriacal anxiety throughout. (Chafman, Brit, Jeum. ^f i/<?w., vii, 391.)
- a. On July 1st, 1874, I was called to Mad. C — . This lady, multipara, and at the eighth month of a fresh pregnancy, had taken some soup at 7 p.m. Feeling her stomach oppressed, she intended to take a small glass of cura9ao, but by mistake swallowed two tablespoonfuls of
tincture of A. She immediately felt sensation of burning in throat, which persisted ; 5 m. later violent pain at pit of stomach lasting J h., at same time heat and considerable perspiration compelling change of linen. There was also some nausea. After ^ h. a small stool with colic, followed by almost irresistible desire for sleep.
b. I saw patient 40 m. after accident. I found her in bed, face red, pulse quick, skin hot and perspiring, complaining of nothing at present but excessive sleepiness. The feeling of burning in the throat had gone off after the first 15 m. I gave Ipec, 3, every 10 m. Between 8 and 10 patient was seized with three more painful cramps in stomach, but shorter and less severe than the first. She then slept all n., and rose lively the next m., complaining of nothing but sleepiness, which passed ofFduring d. There was no threatening of miscarriage. (Imbert- GoURBEYRE, VJrt Medical^ xliv, 12.)
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In Oct., 1867, a man, aet. 69, had a fall. He got up without help, and, feeling bruised all over, took a decoction of 30 grammes of A. flowers. In a very brief space he was seized with such violent symptoms, that he believed himself attacked by cholera, then prevalent in the neighbourhood. Efforts to vomit, extreme anxiety, feeling of constriction at level of attachments of diaphragm, pallor, cold sweat, small and frequent pulse, convulsive movements of limbs alternating with tremor of whole body, were effects of this poisoning. Opium internally, and belladonna in friction along spine, gradually quieted the symptoms ; it was not till after 3 d. of constant care that patient could be considered out of danger. (Cazin, Desplantes mSdicinaUs indigenes.)
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The inconsiderate use of A. may sometimes occasion somewhat
CLve accidents, such as M. Alibert recently saw at the Hopital St. uis, in the case of a man who had been gorged with decoction of A. flowers after a fall. He had obstinate vomiting, vertigo, convulsions, and the symptoms could not be subdued till after some d. (Biett, Diet. des. sc, m^d,, 1812. Probably same as 5. — Eds.)
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On Aug. 6th, 1864, a middle-aged man was brought to the hospital having (on previous e.) swallowed about 3j of tincture of A. For a short time patient had felt nothing but a little burning in the throat. He had slept during the n., but next m., 8 h. after swallowing the tincture, a violent pain had come on at pit of stomach, worse on pressure, with malaise and great weakness. Two h. later patient was found in a state of collapse. Eyes were sunken and glassy ; pupils dilated and insensible to light : pulse about 100, feeble, irregular ; skin cold and dry. He was given 20 drops of laudanum with some brandy ; and after a second dose, aided by warm coverings and hot bottles, began to improve. Next d. he left the hospital quite recovered. (" Arnica, Case of Poisoning by Tincture of," reported by H. Bertin, M.R.C.S., Lancet J vol. ii, 1864, p. 571.)
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Mad. M — , act. 32, took at 10 a.m. on Feb. 23rd, as an emmenagogue, two glasses of an infusion of A. flowers. In \ h. violent vomiting came on, with great congestion of head, headache, vertigo, &c. In afternoon, frequent diarrhoea with sharp colic ; also severe pains at pit of stomach, making her cry out loudly. Between 6 and 7 p.m. a bad fainting-fit occurred. I found her at 8.30 in complete
collapse^ though the attendants spoke of her as already somewhat better ; face was drawn j skin cool, without sweat ; pulse 54, thready* She complained continually of violent pains in stomach, which hot applications did not relieve. An opiate caused pains to diminish up to midnight, when they ceased, and patient slept till m. I found her, on 23rd, still very prostrated, but without pain and more cheerful. Skin was still remarkably cool, pulse 60 and small* No more diarrhoea. On 24th was summoned to her at 6.30 a*m. Violent pains at stomach had returned j she felt congested in lungs almost as if haemorrhage would occur. Catamenia had appeared slightly ; there had been a liquid stool ; pulse was small and slow. The opiate and a hot sitzbath were ordered. Menstrual flow was not increased by latter j and in e. gastric pains became yet more severe. Pulse was scarcely to be felt, 60. Under morphia pains disappeared, and were again checked by it on a recurrence during n. and next e. In m. pulse 80, fuller ; patient complained only of weakness and heaviness of head. From this time, under nux vomica, &c., she continued to improve. (Schumann, Schmidesjahrbucher, 1868.)
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Mdlle. K — , set, 20, took some, in c, of Feb. 24th, for like purpose. She was seized, during n., with violent vomiting, watery purging with continued urging to stool (so that she could hardly quit the close-stool all the n.) and excessive pain at stomach. The continual vomiting brought up only small quantities of tasteless yellowish fluid. Face and extremities were cold j temperature of general surface normal ; pulse full, retarded. The epigastrium only was sensitive to pressure This continued in spite of ipecacuanha and opium, with cold ; but vomiting and diarrhoea diminished. Pains returned yet more severely during n., and remained all next d., being aggravated by hot poultices. Morphia was freely used, and pains subsided, to return again at noon on 27th and 28th. On ist March catamenia flowed freely, and pains gradually and finally departed, leaving weakness and loss of appetite. (Meding, Ibid.^ 1870.)
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A cavalry soldier took, to prevent recurrence of a tertian fever, a wineglassful of an infusion of A. flowers every 2 h. Very soon after first glass he felt a great working in the stomach \ something then seemed to get on the chest and press it j respiration was embarrassed ; there followed pressure on head, swimmings, startings in hmbs. He could not get up \ fell, and was unable to stand. This curious state lasted 4 h. ; each glass renewed it, but with less intensity. (Barbier, Traite de Mature Midicale^ i**37-)
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A guardsman, troubled with palpitation and a convulsive trembling of the 1. arm, was put on a decoction of A, The first glass provoked nausea in a few m. ; at the same time came a general shuddering, drawings extended into limbs, even to extremities of fingers, accompanied with indescribable sensations, also by involuntary movements. The chest could scarcely expand, and the respiratory muscles were in a state of tonic contraction. (Ibid.)
J 2. Louis Meline, «t. 28, big and strong, in excellent health, carried on July 21st too heavy a load, which caused him pain in the back and oppression, without cough or spitting of blood. His mother
S9»
made htm drink a very strong infusion of A. flowers. Soon after, M-^ felt a general agitation, which went on increasing to such a degree that on the 4th d. he had general tetanus of r» side. This state continued 3d., when I saw him. Chloroform inhalation caused cessation of spasm, but for a time gradually decreasing in extent ; and he died on April I St. There was no autopsy* (Turck, Journ, des cmnaiss. mSd,chirurg,, 1853.)
13, I once saw a large dose of A., taken by a young girl for a culpable object, followed by very violent abdominal pains simulating peritonitis, and complicated with a general nervous agitation. {Ibid,)
14, GriHot has observed, from an excessive dose of A., severe vertigo, lasting several h,, and preventing the patient from standing or sitting upright. {Ibid,)
15, In 1870 I attended an architect who had fallen from a scaffolding and was picked up much bruised. He had been made to swallow immediately a teaspoonful of tincture of A. in eau sucre ; and a compress of the same tincture somewhat diluted with water had been applied. Several vomitings had followed ; and when I saw the patient I prescribed Arnica 6, but continued the compresses. At the end of this time the patient was seized with a constant and most fatiguing hiccup, which lasted 48 h. before yielding to nux vomica, (Imbert- GouRB£YR£, loc, cit, Sachs is here quoted as acknowledging the power of A. to induce hiccup.)
16, A woman who had tertian fever for 4 months took 3J of A. flowers in infusion. It caused dulness of sight ; the next paroxysm was more severe. Two d. later she took a yet stronger infusion ; and considerable dulness of sight ensued, with vertigo, trembling, anxiety, violent vomiting and diarrhoea for some h, A long deep sleep followed, from which she awoke m good condition. The fever disappeared. (Bird, Harless' Rhein Jahrbuchery 1825.)
17, On July 1 6th, 1869, Mr. X — , set. 66, gouty, fell violently on one knee. Though pain was severe he was able to return home, but had scarcely sat down when he felt a strong rush of blood to the bruised knee. Fearing gout would settle there he had part bathed with tinct. of A,, for 7 h, consecutively. He also took the drug internally. By e., 10 h. after fall, all pain had abated ; but during n, came on sleeplessness j frontal pain as if part were strongly congested ; pain in temples on coughing, in nucha on standing, and in whole body when lying as if it were on pebbles i vertigo ; bilious vomiting ; mouth cool, with thirst, desire for strong drinks ; blurred vision ; pulse frequent. The next d. he complained of serious difficulty of sight ; frequent diplopia ; hallucinations of vision \ he could not judge of distances and saw only half an object. Intelligence and memory were good i gait uncertain, motion awkward j want ,of appetite ; thirst as before ; still slight vertigo. i8th, — Does not quite know where he is, or recognise rooms he enters. Constantly sees a bright light with , eye, which disappears on closing that eye, but reappears on closing both. These symptoms lasted 4 d. altogether j but the visual hallucinations continued some time after* (Gailliard, Journ, du Diip, Hakn,^ Jan., 1870.)
- tf. Drs, Galoni and Manxoni^ of Rome, describe [Giorn, di Roma^ June, 1867) a vesicular eruption, with redness and swellings resembling phlyctenoid erysipelas, as having followed the local application of A* It commences by slightly raised pink points on the place rubbed, which multiply and increase and become an infinite number of miliary vesicles resembling, though less in size, the eruption produced by croton oiL The eruption, accompanied by tumefaction, extends beyond the points touched by the application, and may be accompanied with fever in proportion to its intensity,
b^ Nothing being easier than to repeat this experiment, we rubbed the posterior part of one forearm with a cloth well soaked in undiluted tincture of A* At first only a uniform redness was produced ; but in 5 m«^ at the root of each hair, a little sharp red point appeared, which soon became a little papule, umbilicated on account of the presence of the hair-bulb* We repeated the rubbing three times in the d., but could not continue it long without causing a little blood to exude from each papule. Next d. they were mostly sunken, but some converted into small pustules \ others had a small scab of dried blood. During and after the friction, on the points touched and a little beyond them, there was a tingling similar to that felt when the electric brush is passed over the damp skin. The eruption ceased with the use of the tincture ; was not produced when this was much diluted ^ and simple alcohol of the same strength produced only a diffused redness without the eruption or sensation described. (Guillemot, ap, cit.)
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Mrs, W — , aet, 50, sprained her ankle on May 26th, and applied a rag saturated with pore tincture of A. In la h. this pro* duced "erysipelas," which was treated with various remedies and applications till the 28th, when I saw her, and found her in very great suffering. A band of infiammation about 3 inches in width nearly encircled the ankle-joint, of dusky-purple colour, upper part raised into large flattened blebs, lower part slightly suppurating ; oedematous for several inches above and below ; the whole most exquisitely tender, and looking most like a severe scald or burn ; general disturbance very slight, save for want of sleep ; one eye slightly inflamed and ItcU swollen i a small erysipelatous patch on n palm« Under arsenicum and belladonna she recovered in about 5 d. (J. N. Blake, Monthly Horn, Rru.^ xviii, S52*)
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Capt. S — burned his foot slightly, and applied a weak solution of A, to it. Some days after, on mounting his horse, he rubbed off a little skin, and again applied A., — a compress soaked in a lotion of 2 drops to 3J of water. Some d. later an erythematous inflammation appeared about the wound with a severe infiltration of cellular tissue- The infiammation soon extended in all directions, invading hands, face, eyelids, r» ear, ^nd r. side of neck. It then appeared that during sleep he had held his hand, wrapped in a compress of A,, to the r, side of his face. The erythema increased for 3 or 4 d,, causing much itching and ending in exfoliation j there came moreover little blebs on face, wrists, thighs, and lower abdomen, some of which burst* (Low. DER, Horn, Umis^ Nov., 1853,)
21 • A lady, of sanguine temperament and v^ty healthy, fell on the
ice and severely sprained her wrist. We applied cloths dipped in an A, lotion^ 20 drops to the oz. These were continued, with alternate use of plain cold water bandages, for 8 or lO d. The sprain being then very much better we did not call for 4 d. On revisiting patient, we found she had persisted with the A., using 30 to 40 drops to the oz. She had observed, for 2 d,, a slight redness of the skin, attended with great itching. On examination, we found the outer side of wrist covered with a small miliary eruption* In 2 d. this had very much increased j the whole forearm and hand were red and very much swelled, the surface covered with numerous small semi transparent vesicles, with red bases ; in some parts they were confluent. There was great heat and excessive irritation from the itching. The eruption, where it first appeared, died away, leaving slight desquamation of the epidermis, but the redness and swelling continued. On 8th and 9th d., swelling had spread above elbow half* way up arm, but no eruption was visible there. On loth d., patient complained of heat and itching of face^ skin became red, and over I. malar bone eruption appeared j swelling and redness soon involved I. eyelids. The course seemed to be, first heat and great itching of skin, then redness, then appearance of minute vesicles, increasing in size, and producing intolerable itching. These gradually subside, leaving slight desquamation and redness. In arm skin remained for some time covered with slight scabs and hard almost like leather. There was no fever, and headache only when tace was affected, (Black, Brit. Journ. of Htjm.y ii, 276,)
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A man of strong constitution, act. 70, fell and bruised his hand. He applied a fomentation of diluted cincture of A. On waking in m., he found injured hand almost black. Dr. Oschenheimer, arriving shortly after, found face, neck, breast, and back in a state of erysipelatous inflammation, 1. hand dark blue, covered with vesicles of various sizes, some as large as a pigeon's egg j pulse was quick, patient depressed. After 4 d, this erythema, with some pustules which had formed in connection with it, went off, and the patient gradually became quite well, {CEsUr, Med. IVochensckr.y 1844, No, 9.)
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A girl who was using an A. lotion for an old sprain came and showed me her knee, which, after having been wrapped in an A. compress some d., showed every sign of bruise ; it was first blackish, then changed to a greenish, afterwards yellowish hue, before it recovered. Patient supposed it was "drawing the bruise out ; '' but as the sprain was of many weeks' standing, even that popular hypothesis would not explain the fact, (Bayes, Applied Homasopathy^ p, 54.)
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a. A gentleman, far advanced in years, was threatened with cerebral congestion, for which I prescribed A, He warned me that A* always produced erysipelas with him. In that case, I said, I will give you such a dose as cannot possibly produce such an accident ; and 1 ordered him the l8th dil. Next d. he had decided swelling and erysipelatoid rash around mouth, affecting especially upper lip.
h, I have another patient, a lady of high rank, whose sensitiveness goes even beyond this. Her husband and sons, fond of field sports, use a small quantity of A* in their bath after an unusually tiring d,, or an
A, lotion or compress for bruises or strains. But under these circuin*
stances, if they go immediately afterwards into the room where Lady — is, she invariably has slight erysipelas of the face, with puffiness of both eyelids and great irritation of the skin. Her last attack of this kind was induced by her having thoughtlessly mixed a dose of a dilution of A* for her husband, one drop of which fell on her finger j and although she immediately washed it off, she had erysipelas in her face next d.* (Ibid, Monthly Horn, Rev,^ xrx, 623.)
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A lady took, for a strain, pilules of 3rd diL of A* Towards e. of 2nd d. face ached, and she fancied she had caught cold. Next m. felt very poorly, took one pilule early and another at noon. Face got, worse ; by e. had every appearance of erysipelas, Felt very ill, and had to stay in bed for 48 h,, by which time swelling had gone down, A week later, after 3 d» of 200th diL, face became hot, stifF, and a little swelled, but soon got right under aconite, (Dyce Brown, ii/^,, xxii, 171.)
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Mrs* O — fell upon her chest against a stack of wood. There was no wound, but she had considerable pain inwardly, especially when she moved or exerted herself. For this she drank an infusion of one drachm of arnica flowers. Soon afterwards she got dimness of vision, trembling and great weakness of all limbs with vertigo and stupefaction. She lay for some time quite faint. Flickering before eyes, ringing tn cars. Intermittent pulse. Scraping in throat, pressure strong in stomach. Then vomiting ensued, but it was long before she felt again strong and well, and in that previously healthy woman there occurred many symptoms, from some of which she still suffers and which were certainly caused by the arnica. She suffered much from congestions, the catamenia were often profuse and attended with pain. Frequent epistaxis. Frequent spasms of stomach, pressure and boring in it ; it feels contracted and then distended with flatulence, swollen until relieved by eructation. Sometimes the L side feels as ^ ulcerated. Nausea and frequent vomiting. Rumbling in belly and frequent tearing pains, then urging to stool. Painful shooting and burning in anus and spasmodic contractions there. Sometimes small pimples broke out which discharged bloody matter. At same time pusillanimity, occasionally anguish, and prsecordial anxiety.
Others have observed spasm of stomach, nausea, and vomiting. Others felt shocks like electricity in various parts of body, dry tongue^ cough sometimes with expectoration of blood, nausea and miliary raah* (Emmersch, Jrchivy xviii, 40,)
- A lady, aet, 60, stout, delicate, nervous, bruised leg in a fell, and arn, in various dilutions of tinct,, and once tinct. itself, had been rubbed into leg and retained there by bandage and oiled silk for 12 d. Bright redness then appearing on front of leg, it was discontinued ; but
next d. reaness nad mcreased, ana " small Diaaaers " began to form, with some itching- On 17th d. Dr. Clarke saw her. There was no constitutional disturbance and no local pain even on walking. Leg
• ♦! know a lady who» having ii years before made too free use of A., could not inhale it without having erysipelatous spots on different parts of body/' (Gail hiAKD,y(mrn. du Disp. Hahn.y iS69fp. 79.)
was swollen and pitted on pressure. Lower portion was coloured red and black with extravasations. There were a few mattery points the size of lentils. Much of epidermis was raised, and clear fluid was oozing at points. Discolouration spread round calf, but was less deep and uniform than in front. There was no tenderness. Under rest, drv warmth, and arsenicum patient soon recovered. (J. H. Clarke, M.D., yfmer. Hom.y Oct., 1885.)
III. Experiments on animals. — I. a. In June, 1873, ^^ injected into the rectum of a large-sized dog, at 2 p.m., two grammes of tinct. diluted with water. After 10 m. the animal became much excited ; it began to frisk, to howl, then to scratch the ground with its paws, and to roll about with cries. Rectal tenesmus next came on, and contractions of the diaphragm, but neither stools nor vomitings. At 2.30 another order of phenomena manifested themselves : we saw the animal tremble on its legs, move in a hyenoid manner, and give way at its hind quarters, extending the legs as if instinctively to enlarge the base of support. Soon this posterior paresis alternated with contractions which bent the creature like a bow, and affected now one and now another of the hind legs, then both at one time. At length these contractions ceased, so that by 4 o'clock there was nothing but great lassitude, retraction of hair, dull eyes, groanings, and hiccuj) ; the animal ended bv rolling itself up and sleeping. Next d. it had regained its usual condition but for several diarrhceic stools.
b. Administered by the mouth, the same preparation, in the same dose, produced in this dog a frothy and very abundant salivation, which lasted I h. ; there were two vomitings, the contractions were much less marked. (Guillemot, op. cit.)
- ViBORG administered an infusion to horses, and found that in moderate doses it increased action of hearty flow of urine, and warmth of skin, and that these effects were accompanied and followed by full pulse, muscular tremors, and depression. In larger doses it produced similar effects in a more marked degree. When injected into their veins it occasioned flow of saliva, heat of skin, general tremulousness^ with roughness of coat, laboured breathing, and full pulse. To these symptoms succeeded general depression, with drooping head and closed eyes. The animal could scarcely stand, and finally lay down quite insensible to all external irritants. Within 2 h. he perfectly recovered. Effects entirely similar, but of longer duration, were observed in a cow. (Stille, op. cit.y sub voce.)
Volume I — Appendix
Amioa. — On p. 391, 1. 6, for " April " read " August.*'
Volume II — Appendix
Arnica.-After II. 27, insert the following : 28. An excitable but otherwise healthy man, in the prime oflife, took for headache pulv. rad. arnic. gr. vj. After 8 m. terrible palpitation, which became so violent that he could hardly utter a word ; look fixed and anxious, general coldness ofbody, and very severe vertigo, increased together with the anxiety and stupefied feeling by vomiting; the jaw hung down. Vinegar removed all the symptoms in h. (HAHNEMANN, Hufeland's Journ., v, pt. i, 8 ; Lesser Writ., 376.)
Volume IV — Appendix
ARNICA.
(See vol. i, p. 379 ; vol. ii, p. 7«6.)
II. 29. A robust lady of 48 took, by mistake, 15 — 20 dr. of tiact. in a wineglassful of water. The taste telling her what she had dooti she swallowed mustard and water until she vomited freely. She seemed very little, if any, the worse for the mishap, till 14 d. after, wbea inflammation began at inner canthus of r. eye, extending in a fcwh. to whole 1. cheek and side of face, then to r. side. Her general condi* tion became more and more involved, till on the 4th d. she becatneso ill that she had to go to bed. She felt so cold and shivery that sb« had a large iire made in bedroom, and put seven blankets and a rugoo
the bed. In 6 — 7 h. she became warm, and flooding came on
d dark) so profusely, that as soon as she attempted to rise it came
»y "all of a gush." The inflammation of the face, which now had
ly blisters upon it, was at once relieved by the flooding, which
5 d. (She had taken belladonna and rhus.) After erysipelas
flooding had gone, she had irritation of skin — itching wheals like
ttlc-rash — between her breasts and on the abdomen, and now (five
:ks after the poisoning) there is a large crop of them on the thighs.
le sensation felt on scratching was " beautiful." Irritation was
relieved by bran-water, but not by simple water. Ever since the
isoning, she stated, her sight had been failing ; there are no spots
tforc the eyes, but everything seems dim, and now she cannot read
Hthout using her husband's glasses (before the poisoning her sight was
extremely good). Her pupils are dilated. There was desquamation
" the skin after the erysipelas. (Patient was still menstruating every
months.) (Burnett, Tht Organo/iy i, aji.)