Valerian officinalis, Linn.

Natural order , Valerianaceæ.

Common names , Valerian; (G.), Baldrian.

Preparation , Tincture of the root.

Authorities. ( 1 to 16 , from Stapf's Beitrage).

1 , Hahnemann; 2 , Franz; 3 , Gross; 4 , Stapf; 5 , Wislicenus; 6 , Andrée, cases of epilepsy, p. 262; 7 , Carminati opusc. therap. 1, 227; 8 , Casp. Hoffm. Off., p., 583; 9 , Dodonæus, Pempt., p. 262; 10 , Haller, Hist. Stirp. Helvet, Indig., p. 210; 11 , Hill on Valerian; 12 , Horstius, Pharmac. Cathol. f. CLX.; 13 , Junker, Therap. General, p. 111; 14 , Marchant, Mém. de l'Acad. des Sci. de Paris, 1705; 15 , Ray, hist. Plant, vol. i, p. 388; 16 , Tissot, traité de Épilepsie, p. 309; ( 17 to 28 , Jorg's Provings, Materialien, etc., 1825); 17 , Engler took infusions of root, 1/4 part of 3 drachms (first day), 1/4 of 4 drachms (second day), 1/4 of 5 drachms (third day), 1/4 of 6 drachms (fifth day); 17 a , same, took 1/2 drachm of powder of root, afterwards 1, 1 1/2, and 2 drachms; 18 , Güntz, took an infusion of 2 scruples (first day), of 1 drachm (second day), of 1 1/2 drachms (third day), of 2 drachms (fourth and fifth days), afterwards of 4 ounces; 18 a , same, took 10 drachms of an infusion of the strength of the root; 18 b , same, 1/2 and 1 1/2 and drachms of powder; 19 , Haase, took various doses of infusions; 19 a , same, took 1/2, 1, 1 1/2 drachms of powder; 20 , Heisterbergk, took infusions of 5 to 8 drachms, of which he took 1/4 part at a dose; 20 a , same, took 1/2, 1, 1 1/2, and 2 drachms of powder; 21 , Kneschke, took 1/4 of infusions of 3 to 8 drachms, no symptoms; 21 a , same, took whole infusion of 1/2 drachm without result, then 1 drachm; 21 b , same, took 1/2, 1 1/2, and 2 drachms of powder without effect; 21 c , same, took 1 1/2 and 2 drachms of powder; 22 , Kummer, took infusions; 23 , Winkler, took various doses of an infusion; 23 a , same, took 1/2, 1, 1 1/2, 2, and 2 1/2 drachms of powder; 24 , Pienitz, took various doses of infusions; 25 , Siebenhaar, took various doses of the infusion; 25 a , same, took 1, 1 1/2, and 2 drachms of powder; 26 , Jörg, took infusion; 27 , Enders, took 1/2 drachm of powder without effect, then 1, and after two days 1 1/2 drachms; 28 , Strofern, took 1/2 and 1 drachm of powder; 29 , Peifer's Thesis, A. H. Z., 19, 201, took 4 scruples tincture in the morning fasting; 29 a , same, took powdered root; 30 , E. D. Abell, Bost. Med. and Surg. Journ., vol. liv, 1856, p. 117, Mr. E., æt. forty, took nearly 1/4 ounce of the extract; ( 31 to 38 , Barralier, des Effects phys., et de l'Emploi thérap., de l'Huile essentielle de Valériane, Paris, 1860); 31 a , healthy person, æt. sixty-four years, took 2 drops tincture; 32 , another person took same; 33 , effects of 6 drops; 34 , 35 other provers took same; 36, 37, 38 , other provers took 10 drops each.

MIND

Extremely delirious, attempting to get out of the window, threatening and vociferating violently. He complained of not being able to see, and did not recognize me nor members of the family about him, and imagined himself away from home, and beset with all sorts of danger, from which he was attempting to escape, although unable to walk without staggering from side to side, 30.
Agitations, 34.
Remarkable liveliness with great courage, with slight acceleration of the pulse, 23.
More joyous and active mood than usual, in the evening (second and third days). 17.
Very joyous mood all day (first day), 29.
Unusually joyous mood (soon), 23.
More cheerful than before; he comprehended everything more easily than before; a sort of joyfulness, as is sometimes felt after drinking coffee (first day), 2.
Morbid irritation of the nerves; although he appears more cheerful and vigorous than before, nevertheless his eyes, arms, knees, feel very weak, in the forenoon (after twenty-eight hours, second day), 2.
(Seriousness) (second day), 2. [10.]
Anxiety, 16.
Anxious, hypochondriac feeling, as if the objects around him had been estranged from him; the room appears to him desolate, he does not feel at home in the room, he is impelled to leave it (from the vapor), 5.
Fearfulness in the evening when sitting in the dark (imagining that some one might hurt him), (first day), 2.
Ill-humor, 28.
Disinclination for mental work, 38.
Great flow of ideas, one chasing the other, as in intoxication; confused, faint recollections of former thoughts and action, presented themselves to his mind, but they chased one another with so much rapidity, that he at last became quite stupefied and lost his thoughts; he felt like one who is dreaming (from the vapor), 5.

HEAD

Head much confused (second day), 26.
Cloudiness of the head (from the vapor), 11.
Feeling of intoxication and vertigo when stooping; sensation as if everything were turning around her (after half an hour), 4.
Rush of blood to the head, 21a, 21c, 26. [20.]
Rush of blood to the head, with a feeling of fulness, especially under the vertex, 26.
Symptoms of congestion of the brain; pressing headache, extending from the right frontal region over the whole head, sometimes seated in the eyes and making them sensitive to every slight effort, at times also passing down to the angle of the lower jaw of the right side and causing a sensation as if asleep, 22.
Feeling of fulness in the head, apparently caused by rush of blood to the head, similar to the effect of a tight neckcloth (soon), 18a.
Dulness of the head, changing to a pressive-drawing pain, especially in the frontal region, 22.
Sudden stupefaction in the head, causing him to stagger and almost to fall to one side, when standing, 3.
Stupid feeling in the head when stooping (after a quarter of an hour), 4.
Feeling in the head as after intoxication, somewhat elated (after half an hour), 4.
Heaviness of the head, 32, 36.
Headache, 18b, 36, 38.
Headache at night, 18. [30.]
Intense headache, 35.
Headache, usually in the forehead, at times very intense, 31.
Pressive headache in one or another part of the head, 26.
Headache an hour after dinner; pressure over the eyes, as if the eyeballs would be pressed out, especially when moving them, at 1 P.M. (after four hours), 2.
Headache, the aching especially violent over the orbits , at 11 P.M. (second day), 2.
Transient pain as if he had just had a hard blow on the vertex, a painful, stupefying, contractive sensation, affecting the whole head, although it emanates from the vertex as the centre, afterwards disappearing from the other parts of the head, and lastly from the vertex, .

EYE

The eyes shine, 2. [60.]
Pressure in the eyes only in the morning after rising; the margins of the eyelids seem swollen and sore , especially in the region of the left inner canthus; they look red (third day), 2.
Sensation of pressure in the right eye, as of a stye, at noon (after three hours), 2.
Smarting in the eyes, as if occasioned by smoke , at 3 P.M. (after six hours), 2.
Burning smarting in the eyes, at 10 A.M. (second day), 2 . [These affections of the eyes, which had been entirely cured by Valer, without any disposition for such pains existing before, were excited at intervals for the period of four months, the cause being frequently unknown; this shows that the symptoms of Valer. are deeply rooted in the organism, and that it is with great difficulty that they are removed. In this respect it is like the mercurial sufferings which frequently last years, and during the whole of one's life, and sometimes return after being dormant for months. There are no mercurial or valerian particles in the system; the organism had been so violently and deeply affected by the poison that the drug-disease had become permanently and constitutionally ingrafted upon the system. -FRANZ.)
Orbit.
Painful drawing around the orbits, more toward the side, especially when stooping (after half an hours), 3.
Lids.
Eyes somewhat agglutinated (first day), 29.
Pain and swelling of the eyelids (from 1 to 2 P.M., third day), 2.
Stitches in the inner canthus, at 11 A.M. (third day), 2.
Ball.
Tearing in the right eyeball (from the vapor), (after two hours), 2.
Pupil.
The pupils are somewhat dilated, at 9 A.M. (after half an hour), 2. [70.]
Pupils of eyes dilated to nearly whole extent of cornea, even when approached by a lighted candle, 30.
Vision.
Dimness of sight, early in the morning, and pain in the eyes, as if he had not slept sufficiently (third day), 2.

EAR

Slight jerkings in the right meatus auditorius (after a quarter of an hour), 3.
Crampy drawing in the left ear, 3.
Ringing in the ears, in the evening when in bed, and illusion of hearing; he imagined he heard the bell strike, at 10 P.M. (after fourteen hours), 2.

NOSE

Violent sneezing, 3.

FACE

Face injected, 34. [80.]
Quick painless twitching from time to time beneath the skin of the left cheek, which he thought might be seen; this was not, however, the case; it went off for a short time by moving the hand over the cheek, 3.
Repeated transient crampy jerkings in the region of the left malar bone, 3.
Painful crampy drawing in the right malar bone, transient (after a quarter of an hour), 3.
Pimples in the white of the upper lip and on the cheek; small white vesicles on an elevated red border, painful to touch (fourth day), 2.
A pressure (almost resembling a darting) in the right side of the lower lip and in the gum of the right canine tooth (after one hour), 2.
Repeated dartings, as of electricity, in the right ramus of the lower jaw (after seven hours), 3.

MOUTH

Toothache, 1.
Drawing in the teeth of the lower jaw from before backwards, and in the upper jaw from behind forward, 3.
Shooting pains in the teeth, 1.
Feeling of dryness in the tip of the tongue, for a quarter of an hour, without thirst, early in the morning (after three-quarters of an hour), 2. [90.]
Constriction of the tongue (after a few minutes), 29.
Dryness of the mouth and pharynx, followed by salivation, 35.
Gradually increasing sticking pain in the region of the velum pendulum palati, accompanied towards the end with a bitter taste in the mouth and accumulation of saliva, inducing cough (after three-quarters of an hour, from the vapor), 2.
Profuse and offensive salivation, immediately, 33.
Bitter taste on the tip of the tongue, a quarter of an hour after eating meat and vegetables, when licking the lips (after three hours), 2.
Previous to dinner he has a taste and smell as of fetid tallow, at noon (second day), 2.*
*Early in the morning, after waking, he has a flat slimy taste in the mouth, 3.

THROAT

Dryness of the throat, 38.
Scraping feeling in the throat, 25.
Scraping in the throat, lasting several minutes (soon), 18a. [100.]
Scraping sensation in the throat, with an ineffectual desire to hawk (after half an hour), 4.
Great dryness of the pharynx, 36.

STOMACH

Appetite.
Violent appetite at dinner, affecting the stomach with a sort of nausea (canine hunger); although he remains indifferent when thinking of eating, yet he eats with much relish and a large quantity, at noon (after three hours), 2.
Great hunger (after a few hours), 37.
Loss of appetite, 25a, 28, 36.
Great aversion to tobacco (the prover was a great smoker), 37.
Disgust for food, from large doses, 31.
Eructations.
Frequent eructations, 19, 19a, 37.
Frequent eructations tasting of the drug, 28.
Insipid eructations, 31. [110.]
Early in the morning, immediately after waking, risings tasting of Hepar sulphuris, 3.
Eructations tasting of the drug, 20, 22.
Tasteless eructations (after a quarter of an hour), 29.
Warm rising from the epigastric region, arresting the breathing, 3.
Frequent empty eructations, 3.
Offensive eructations, 32.
Frequent empty risings before the meal (after two hours), 2.
Gulping up of a rancid fluid , not rising into the mouth (heartburn), at 4 P.M. (after seven hours), 2.
Nausea and Vomiting.
Nausea (third day), 29a, 36.
Slight nausea (after a few minutes), 29. [120.]
Long-continued nausea, 29a.
Nausea amounting to vomiting, 28.
Nausea and eructations, 38.
Nausea and inclination to vomit, on rising in the morning, relieved after eating and in the open air (second day), 29a.
Nausea, with desire to vomit, as if a thread were hanging in the throat, arising from the region of the umbilicus and gradually rising to the fauces, and exciting a copious accumulation of saliva, .*

ABDOMEN

Hypochondrium.
Painful jerks in the right hypochondrium, 3.
(Pressing sensation in the left hypochondrium, just beneath the last short ribs, while in bed in the morning; on coughing or deep breathing it became a cutting pain), 20a . [Possibly caused by a cold.]
Sides. [150.]
Two evenings in succession, after 10 o'clock, he is attacked with violent colic in the left side of the abdomen, as if there were subcutaneous ulceration (second and third days), 2 . [The principal times of day when Valerian produces its symptoms are noon and the first part of afternoon and evening and the hours before midnight; the abdominal symptoms especially are felt in the evening. -FRANZ.]
Dull sticking, intermittent pressure on the left side and over the pit of the stomach, in the region of a cartilage of the ribs, 3.
Single stitches in the left side, below the short ribs (after a quarter of an hour), 4.
General Abdomen.
Bloated abdomen, 3.
Distension of the abdomen, 26.
Great distension of the abdomen, causing restlessness at night, 29a.
Abdomen moderately distended (first day), 29.
Hard abdomen, 1.
Much very offensive gas from the intestines, 26.
Rumbling and gurgling in the intestines, with some cutting pains, followed after half an hour by a normal evacuation, 25. [160.]
Rumbling and colic in the stomach (after a quarter of an hour), 29.
Constant rumbling in the upper abdomen (second day), 29a.
Rumbling and gurgling in the abdomen, 25a.
Feeling in the abdomen as if it would become excessively distended, even to bursting, 1.
Pain in the abdomen when drawing it in, like a pinching and cutting, 3.
The whole evening he feels a pain in various parts of the abdomen, which is at one time felt as a pressing in the umbilical region (second day), 2.
Aching pain in the abdomen, 1.
Dull aching pain in the abdominal muscles, as if bruised, or as if from a cold, worse during an inspiration, .

RECTUM AND ANUS

When emitting flatus the baby presses very hard, causing the dark-red rectum to protrude, when a few drops of blood fall out, 3.
Boring pain in the left side of the rectum, when standing, apparently, 1 , in the sphincter, at 1 P.M. (second day), 2. [180.]
Boring in the rectum, at 10 P.M. (second day), 2.
Stitch in the rectum, when standing (after one hour), 2.
Violent tearing in the anus, when moving a little while sitting, 1 ; at 2 P.M. (third day), 2.
On getting up from stool he perceives a severe tenesmus in the anus, as if diarrhœa would set in; this disappears gradually, but returns with great violence in a few hours, obliging him to go to stool again, when he has a natural evacuation, 3.
A bubbling pressure above the anus, in the region of the os coccygis, apparently close to it, at 9 A.M. (second day), 2.
A bubbling pressure over the anus, in the parts covering the os coccygis, at 9 A.M. (second day), 2.
(When emitting flatus the baby cries and presses; occasionally he passes a little blood by the rectum), 2.

STOOL

Diarrhœa, 19.
Diarrhœa twice, with tickling at the anus, in the evening (second day), 29.
Violent diarrhœa, in the morning (third day), 29a. [190.]
Two diarrhœic stools, preceded by rumbling and cutting in the intestines (after seven and nine hours), 18a.
Frequent evacuations, 10.
(The baby, who had had frequent loose stools, has now many more looser and more watery discharges, in which solid particles, resembling pieces of curdled milk, are floating), 3.
Pasty stools, 24.
On the first day the stool looks natural; after twenty-four hours he has a greenish papescent stool, with some blood, 2.
Stools more frequent than usual, always evacuated with some effort, 26.

URINARY ORGANS

Stitches in the region of the kidneys, when sitting down (after two hours and a half), 2.
Transient clawing in the region of the bladder (second evening), 2.
Constant desire to urinate, which he insisted upon doing through the window of the room, 30.
Frequent emissions of urine, 7, 8, 12. [200.]
Frequent emission of urine the first three hours, 2.
Increased secretion of urine; on standing the urine deposited a sediment of brown flakes, 23.
Increased secretion of urine, 19, 19a.
Very abundant, highly-colored urine, 34, 35 , etc.
Urine very abundant, more highly colored, and of a stronger odor than natural, 31.
Urine dark brown, 26.
The urine seemed to contain bile, 26.
Urine turbid, depositing a whitish sediment (fourth morning); depositing a turbid sediment (fourth day), 17.
White sediment in the urine, in the morning, 20.
Urine dark red and turbid, depositing a vermilion-red sediment, 23. [210.]
Urine brownish and turbid, with a brickdust sediment, 28.
Brownish flakes in the urine, 23a.
Urine turbid, depositing a slimy white sediment, 17a.
Urine deposited a cloud, 20a.
Urine depositing a sediment, 18b.
Very copious sediment to the urine, the upper part of which was pale, the lower thick, turbid, and reddish, 27.
Mealy sediment in the urine, 18.

SEXUAL ORGANS

Creeping and drawing in the penis, as if it had gone to sleep; frequent erections the day previous, early in the morning (third day), 2.
Tensive-gurgling pain in the right testicle, when sitting, at 5 P.M. (second day), 2.

RESPIRATORY ORGANS

Frequent hacking cough, 36. [220.]
Dry cough, 36.
Difficulty of breathing and anxiety in the chest, after the usual breakfast, at 9 A.M. (second day), 2.

CHEST

Transient oppression of the chest, in the region of the lower true rib of the right side (from the vapor), 2.
*When walking, he feels a pressure across the lower half of the chest , with oppression of breathing, at 10 P.M. (third day), 2.
Darting-tearing pain in the chest, 1.
A few sudden jerks, like electric shocks, below the right axilla, 3.
Sudden stitches in the chest and in the region of the liver, from within outward , causing him to start in affright, at 2 P.M. (third day), 2.*
Frequent stitches in the chest, during a slow horseback ride, at 5 P.M. (third day), 2.
Violent stitches and pressing from within outward, in the region of the last true ribs, when standing , at 8 P.M. (third day), 2.*
Dull stitch, resembling a pressing from within outward, in the left side of the chest (below the axilla), during an inspiration, especially a deep inspiration; the stitch lasts as long as the inspiration ; external pressure excites likewise a sore pain, 3.

HEART AND PULSE. [230.]

Sudden stitches in the region of the heart, when sitting erect or standing, abating when stooping, only during an inspiration (after two hours), 2.
Palpitation of the heart, 1.
Increased pulse, 7.
Pulse 90, in the first quarter of an hour the beats are full and vigorous, in the second the diastole is shorter, the whole body being agreeably warm, and a tremulous anxious sensation being experienced, which seems to come out of the abdomen (after two hours), 2 . [The first and most rapid effect of Valerian, which precedes any after symptom, is an acceleration of the pulse and congestion of the head. -FRANZ.]
The pulse is somewhat accelerated and irregular, two or three beats being occasionally quicker than the others; at the same time it is more tense, 3.
Pulse 85, at 10 A.M. (third day), 2.
Pulse 78, the beats of the heart being weak and scarcely felt (after three-quarters of an hour), 2.
Increase of 4 or 5 beats of the pulse (after a quarter of an hour), 26.
Pulse somewhat diminished, subsequently (after three hours) rose by 20 beats, 31.
The pulse at first fell 10 beats, but subsequently rose higher than the normal, 32. [240.]
Pulse 80 before taking, fell to 62, and afterwards rose to 96, 33.
Pulse 64 before taking, fell to 56, afterwards rose to 78, 34.
Pulse 80 before taking, fell to 64, and afterwards rose to 90, 35.
Pulse 68 (before taking), 56 (after one hour), 78 (subsequently), 36.
Pulse 72 before taking, fell to 60, afterwards rose to 74, 37.
Pulse 70 before taking, fell to 52, then rose to 72, 38.
Pulse 69 (before the experiment); rose to 75, where it remained for some hours (after two hours); associated with rush of blood to the head, feeling of fulness and increased warmth of the face, 21a.
Pulse frequent, tremulous, and irregular, 30.
Pulse unequal, in one minute 60, and in the next 90; weak and small, in the forenoon (after two hours), 2.
Pulse small, 36.

NECK AND BACK. [250.]

Piercing drawing, with pressure from the nape of the neck to the occiput, when bending the head backwards, at 11 A.M. (after two hours), 2.
Drawing pain in the back, 1.
Rheumatic pains in the scapulæ, 1.
Intense pain in the left lumbar region above the hip, as if he had strained the part much, worse when standing, and especially when sitting, than when walking, 3.
A drawing transversely across the small of the back, in the evening, when in bed (first day), 2.

EXTREMITIES

After walking a little, he feels a stiffness and painful weariness in the bends of the arms and knees, at 5 P.M., 2.
Rheumatic pains in the limbs, 1.
In the muscles of the left arm, from the shoulder down to the fingers, a very painful drawing, mixed with single stitches; a sort of tearing, which is neither increased or decreased by any position of the limb ; after taking a second dose the tearing returned much more violently (although it had disappeared for several hours); it disappeared afterwards while walking, after a violent stitch in the knee (so violent that she was scarcely able to walk), and was replaced by a pain which moved up and down from the knee to the toes, and back again ( felt less when walking than when sitting ); finally it affected likewise the right foot, although less, 4.*
Slow, painful drawing and jerking, as if in the bones of the upper and lower extremities, when sitting quietly, 3.*
Repeated darts as of electric sparks in the middle of the left thigh, when standing, followed by a bruised pain in the same part, 3 . [On comparing symptoms which Valerian causes in the limbs, they will be found very similar, both as respects the parts (upper arm, thigh) and the nature of the pain. If, in a practical case, such symptoms should occur in the lower limbs, whereas they have been observed in the upper limbs by the proves, the remedy may nevertheless be employed in spite of the difference. The symptoms of the upper and lower limbs alternate frequently, both in the disease and the proving of drugs. -FRANZ.] [260.]
Bruised pain in the limbs, 1.
Paralytic numbness in the limbs, 1.
Paralytic pain in the knees, elbows, and shoulder-joints when ceasing to walk (after four hours), 2.

SUPERIOR EXTREMITIES

Shoulder.
When laying the left arm on the table and bending it, while writing, a drawing pain in the deltoid muscle, from above downward, and in the bend of the elbow; if the lets the arm hang down the drawing changes into a feeling of heaviness, pervading the whole arm as far as the fingers, as if the limb were turgid with blood (after three-quarters of an hour), 2.
A stinging pain in the region of the posterior border of the deltoid muscle, at 11 P.M. (second day), 2.
Smarting pressure, as from an excoriation or dull stitch, as with a hard blunt instrument, in the region of the shoulder and in other places, 3.
Arm.
Dull pressure, as with the tip of a finger, in the region of the head of the humerus, 3.
Crampy darting tearing, like an electric shock, repeatedly through the humerus, in the bone, intensely painful, 3.*
Crampy drawing in the region of the biceps, in the right upper arm, from above downward, while writing (from the vapor), 2.*
Sudden crampy drawing (a sort of jerking) in the muscles of the upper arm, just above the bend of the elbow and in the outer muscles of the thigh, at noon (fourth day), 2.
Elbow. [270.]
Pain as if bruised in the bends of the elbows, when writing, afterwards extending as a drawing pain along the biceps muscle of the upper arm, from 7 to 9 A.M. (third day), 2.
(Tearing in the elbow-joint), 2.
Stitches below the tip of the elbow, at 6 P.M. (second day), 2.
Forearm.
Tearing in the inner side of the forearm, from below upward, at 4 P.M. (third day), 2.
Hand.
Tremor of the hands, heat and redness of the cheeks, with warmth of the rest of the body, while writing; at 10 A.M. (third day), 2.
Sudden violent jerks in the hand, which disappear again immediately; the place is afterwards painful to touch, 3.
Fingers.
Stitches in the middle phalanges of the fingers, in the bones, at 11 P.M. (third day), .

INFERIOR EXTREMITIES

Hip.
Twitching and jerking in the muscles of the right hip, 3.
Paralytic pain from the ischiatic region and great trochanter of the right side down to the patella, so that walking was very difficult, 29a. [280.]
Feeling of heat like a burning pain in the left hip in bed, at 11 P.M. (third day), 2.
Thigh.
Drawing in the outer side of the thighs from above downwards; it is felt only when extending the lower limb sideways; early in the morning (after two hours), 2.
Crampy pain in the front part of the thigh, extending as far as the groin, at 10 P.M. (second day), 2.
Pain as if bruised from the middle of the right thigh to above the knee, along the outer side, while riding in a carriage, especially when the carriage jolts; in the afternoon (after six to eight hours), 2.
Crampy tearing (tearing-darting) pain in the outer side of the thigh, extending into the hip ; in the afternoon (fourth day), 2.*
When beginning to walk, especially when making a false step, a clawing the bend of the right knee, at 4 P.M. (second day), 2.
Knee.
Excessive weakness in the bends of the knees and ankles, with a bruised pain transversely across the thighs and in the small of the back, in the morning after rising (after ten hours, third day), 2.
Dull pressure recurring at intervals above the left knee, transversely across the thigh; afterwards descending again from the thigh to the knee, 3.
Tensive pain from the bend of the knee through the whole calf, when sitting; at 1 P.M. (second day), 2.
Pain in the patellæ (fourth day), 2. [290.]
Tearing in the bends of the knees when sitting or standing; from 11 to 12 P.M. (second day), 2.
After a violent stitch in the left knee she feels a pain extending from the knee to the toes, and back again, afterwards affecting also the other limb; preceded by pain from the shoulder to the fingers, 4.
Leg.
Excessive heaviness and lassitude of the legs when standing, going off when sitting (after a quarter of an hour), 3.

GENERALITIES

Tremulousness, he has no rest anywhere, as one feels when expecting a joyful event (after one hour and a quarter), 2.
General malaise, 36.
General weariness, especially of the extremities, 38.
Great debility and drowsiness in the evening (second day), 2.
General discomfort, 18b. [320.]
General discomfort in the whole body, 28.
*Drawing in many places, now here, now there, like transient jerks, 3.
Twitching and jerking in various parts of the muscles, superficially, 3.
Smarting pressure as if excoriated, or dull sticking, as with a bard, blunt tool, at a small spot in various parts, 3.

SKIN

Eruption, first red and confluent, afterwards numerous small white, hard, elevated pimples, on the arm and chest, 2.
Painfully disagreeable itching in the axilla, at 3 P.M. (third day), 2.
Smarting as if excoriated, in various places that could be covered with the tip of the finger, 3.
Smarting in the outer side of the left knee, as if excoriated, 3.

SLEEP

Yawning and stretching of the limbs, 3.
Repeated yawning with chilliness, soon, 33. [330.]
Drowsiness, soon, 33.
Great tendency to sleep, 36.
Tendency to sleep and irresistible sleepiness, 38.
She and her baby sleep more quietly than before, without any anxious or confused dreams (curative effect), 3.
Sleepiness followed by profound sleep for two hours; on waking the headache had disappeared, 35.
Somnolence, 34.
*Sleeplessness, 1, 18b.
Unusually wide awake in the evening and restless at night, could fall asleep only towards morning, when he had vivid dreams, 17a.*
Sleep restless (third and fourth nights), 17, 18 ; (first night), 29.
Sleep very restless, disturbed by pain in the stomach, 26. [340.]
Tossing about in sleep, 1.
Sleep disturbed by dreams, 17a.
In the second night the sleep is disturbed by anxious and partly voluptuous dreams; for instance, that he is driving in a carriage through deep water, 2.
In the first night the sleep is disturbed with many confused dreams; early in the morning he feels very tired, 2.
Much dreaming during sleep, 26.

FEVER

Chilliness.
Chilliness, 1.
Chilliness at intervals during the evening (second day), 29a.
Thrills of chilliness creep over the whole body from above downward, 3.
Tremulous, transient chilly feeling, at 11 A.M. (after two hours), 2.
Sensation of icy coldness in the upper half of the head, when pressing the hat firmly on the head; 5 P.M. (third day), 2. [350.]
Paroxysms of shuddering from the nape of the neck downward, 3.
Heat.
Synochus, 1.
Constant heat in the whole body, and uneasiness (first four hours), 2.*
Heat the whole forenoon, and sweat during the slightest motion (third day), 2.
Heat and sweat over the whole body, especially in the face, as soon as he begins to walk (first day), 2.
During dinner he feels heat in the whole body and face, with sweat in the hair on the forehead (after three hours), 2.
Heat of the skin, 36, 37.
Feeling of heat in the whole body and face, with sweat in the hair on the forehead, during dinner (after three hours), 2.
Increased heat of the skin, 34.
Increased warmth of the body the whole day, especially during motion, with sweat breaking out on the face, on the forehead, etc., the pulse being strong, and 80 to 90 (first day), 2. [360.]
She feels warm all over, except in the region of the hip, where she feels as if cold water were poured over her, 3.
Sensation of increased warmth spreading over the whole body, lasting a quarter of an hour, passing off without perspiration, 20.
Increased warmth the whole day, with quick and frequent pulse (second day). 2.
Increased warmth, 17.
General warmth, 26.
Agreeable increase of internal and external warmth (first two hours), 2.
Transient feeling of heat in the head when stooping (after a quarter of an hour), 4.

CONDITIONS

Aggravation.
( Morning ), Pressure in eyes.
( Night ), Headache; sweat.
( Inspiration ), Aching pain in abdominal muscles; stitch in left side of chest; stitches in region of heart.
( Sitting ), Pain in left lumbar region.
( Standing ), Pain in left lumbar region; pain in ankle.
( Stooping ), Feeling of intoxication and vertigo; stupid feeling in head; drawing in orbits.

VALERIANA.