Kalmia latifolia

Volume III — Main text

KALMIA.

Kalmia iatt/otia, L. Mountain laurel. Nat. Ord. Sricacea.

I. Provingi. — I. Bemlert proved drug on 6 penAJnii beside? hiiniclf. They are undescribcd, but a and c were women.

a reports, Irom 30th, headache, dizziness, and nauitea; shock toward* occiput from back ot neck, with heat j pain in forehead (e.), aUo over eyes, seeming to move backwards and down neck externally on both sides, then ceasing, and followed by pain in I. shoulder j alight aching in tbrehead, sometimes shooting down ro eye .teeth, wopit now in one placcinow in the other; frontal headache every d., extending to root of a r. upper molar j on getting out of bed rending in head, followed by «me in h^ps and legs, even to feet ; tearing in nape ; stinging in maxillary bone$; itching in face at n. ; stitches in lower chest; uterine pam (sucnas ^hehad 3 — + yean* bctore); lense of weakneM in abdomen, rising up into throat, relieved by eructation, but when intense soon returning; Mrnse a* of running along >pine with iveariness in leg*; pressing in r. iidc ; rending In shoulder; recurring stitches in hands; ^liIch from r. side into hip (e.) ; stitches in knee externally (e.) and in .••oles ; slight pain in I. hand and Angers, also in 1. leg down to heel, where therr was twitching,

b. From fiame, — pain within head, with sensation when turning of something loose diagonally across vertex; pulsating pain in forehead.

c. From same, — for several d. togetlter frontal headache on waking, sometimes followed by rending in bone* of r. or 1. face or on venex ; pain over eyes ; rending in r, forehead passing downwards; stitches in upjier maxilla and zygoma; menses, on ^jh d. of proving, came 8 d. too early, next time 14 d. too late; scratching in throat, causing cough, n. and d. (al<« in a and 7, in former with mucous expectoration in e.) ; <<tiichcs in toes; pain in r. arm and rending in 1. leg, while at rest, going off on standing up, extending in less degree along whole I. side and arm; rending in r. shoulder, 1. arm, r. lower maxillary bone, and flesh of whole 1, leg.

d. From ist, taken 3 times a d,, — vertigo, on stooping and looking down; rending across forehead.

e. From 30th, — tearing in I. forehead, extending to temple.

f. From same, — frontal headache on ri-*ing in m., increasing afterwards j rending from I. elbow down arm to index, which is flexed in a jerking manner, and from knuckle ot r. little finger up to elbow \ pains in r. hand ; pain in bones of r. middle foot.

g. From same,— rawntrw and scraping in throat, with ptin on BWmllowiiig^ and throbbing in 1. tonsil.

h. fi— himself reports ^roni i^N — glimmering before eyes when looking dovmvvards, with belching of wind and some nauKa alld. ; fine stitchet, aAd st n. itduiq; in 1. side ot throat. (Heking, Amtr. Arzm.)

s. Clark proved and dil. on a young woman, who took % dr ca^ c for 6 4. After some d. more the repeated proving, with similar results. Aversion to hmiwmcnt or exercise ; restlessneitft and fre<)uent turning in bed, unpleasant dreanUt — '^'"g and even getting up and walking in ftlcep; coraneM and shivering on two d. ia succession * pres'sive pains in whole back of head, with fntquent duurp dartinjr its r. side \ pam in head on waking in m., and in e. ; pain at top of ncad ■• fl bound with cord ; strong pain in temples and fbreheaa } itching of cjrea, Mrfasdi whtn rubbed ; pain in eyes, which makes it painful to turn them ; scnae of in muscles around eyes and in lids; tongue white and dryi lips swollen, diy, stiff, in m. ; thirst, with dr)-ness of throat causing dysphagia ; occauonal pain abdomen ; pain in 1. hepatic region ; menses late, and accompanied wiui pi loins, back, and front of^ thighs; sensation in chest, as if strained by lifting; | pain in three upper dor»l vcrtebne, extending through shoulder-blade | con m spine, sometimes worst in lumbar region, with great heat and buminff i shot! Ider- blades ; great mariness in e., particularly in extrrmitiet, to that it it impossible to go upstairs; numbness of limbs as if asleep. (Jhid^

1. Freitag proved drug on man named Kummer, otherwise undciciibcdi

a. From ist dil., a few globules every and d.for 10 d., — dulnctain bead (lat d.); heaviness in r. head for short time but severe ; towards e. same sensatioa on 1. aide ; strong pressure in r. temple (3rd d.) ; severe headache at noon of tnd d., wane on L; cloudiness before eyes (3rd d.) ; sharp stitches in eyes, towards e. of and d.y and ia r. eye in m., — on 3rd d. same with violent pressing ; eyes feeling dim and weak { kduag in eyes ; severe stitches in r. ear (n. of snd d.) ; short pains in r. teeth (e, of jid d.) | violent pressure in 1. neck and at same time in 1. foot } sticking pain deep sMMlcr I. shoulder-blade (3rd n.) ; drawing pain of short duration at inner side of 1. ami (lid d.) i p»<n in whole r. arm, lasting for weeks; pain in 1. wrist, so that hand aacm palsied ; pain in all fingers of 1. hand at same time (3rd d.) ; pain in 1. Iboc »t d« again, violent, on xoth d.j pain in 1. arm above elbow, and soon afterwarda bttweea elbow and hand, frequently alternating between two places fat i h., and followed \m pain in both legs below knees, which extends to feet ; pain in bend of 1. knee, «HuCB IS immediately followed by very severe but brief pain in J. index, and later in r, fboti pressing pain in 1. shin, and in muscles of 1. arm, with same in r. foot. Thcae in limbs, continually changing from one place to another, lahted all the time was being taken, and 3 weeks later.

b. From 30th taken every 4th d., — vertigo, with some nauwa, attended with in head and limbs ; severe pressing in temples and on both sides of neck { pa' throbbing in whole 1. head, with stitches in 1. ear and behind r. j glimmerinv eyes, exactly in line of vision, so that it is impossible to di^inguish worn reading,— it seems as if small points were continually moving before eyca, for §k.lt

3 p.m. of 2nd d., followed by nausea, and then some dulness and aching in hcadi pressing in eyes, attended by pains in arms and hands, in lower extremities «lown ta feet, and sometimes in r. abdomen } stitches under ). eye jf severe stitchet in caiB at

4 p.m., followed by pain in arms; pain behind r. car, and in r. neck and Icf { paia in upper teeth ; stitches in tongue; pressing in throat and nausea, with stitnea in eyes; pain in r. abdomen, followed by pain in r. natis (after 6th dose) | oparcadon of chest. — later with dyspnoea, dulness of head, nausea, and various pains (iafter f^ dose) ; stitches under 1. arm j pains in 1. hand, particularly in palms clow to wnlL and sensation as of paralysis in r. hand (after 6th dose) ; pain in J. knee and Ibotpaili also in r. foot (3rd d.) ; peculiar pains along outside of 1. leg, frequently repcassd} pain in 1. fcwt (after 5th dose) ; transient paJns in 1. elbow, arm, ancf knee in bl, na in both arms p.m., — while lying not felt (3rd d.) ; pain in r. shoulder, ]. ama faaiw ticularly elbow), and both legs (especially knees); pressing in 1. shin, later mL shoulder and arm, followed by same on r. side j sticking pain in r. index, ^, aoon

• The other symptoms were felt more or less every day.

f Kummer's symptoms of head and eyes were worse towards e., and in open A,

kalmia.

n

followed by severe pain in hollow of r. knee and in caJf, attended with dyKpn<Ki (ahcr 6th dow) ; frequent pain* in muscles ot extremities, with dulnesx of head, vertigo, and some nausea; sprain.like pain at times in feet and hands; preuing pains tn whole body (ij h. after 3rd dose). K— 's pains were most severe while moving, disappearing on lying down. (^Ibid,")

1. Haeseler proved 30th, manner not specified. Fantastic dreams; 6uent coryza with frequent sneezing and perceptibly increased scn^e of smell ; tingling in salivary glands, immediately after eating, attended with sense of fermentation in ofsophagus and copious salivation ; dry skin and cracked lips ; continued ^i^ing of slippery mucus in mouth, with tickling in larynx; pressing m scrob. cordis, relieved by sitting erect, but aggravated by sitting bent, with feeling under scrob. as if something would be squeezed out ; easy soft stool, with pressing in rectum ; frequent emission of yellow urine, in increa^d quantity ; couen, with easy expectoration of grey, smootn, unctuous matter, which has a putrid saltish taste; oppression and shortness of breath, which obliges him involuntarily to breathe quickly y sensation as if spinal column would break from within outwards (IbU.)

2. ReiCHELM proved 3rd dil., manner unknown, irritable disposition towards e., continuing next m. ; oppression in head in e., continuing to some extent next m, j heat in head (m. of 5th d.); about 10 p.m. in bed momentary shivering without coldness from vertex to neck, without headache, under scalp^ attended with cracking noise, and with sense of alarm, but without palpitation, — as if body were surcharged with electricity (repeated 4 times in ) h., and ending with ^ounil a» of a horn before cars); pressing pain in forehead, especially r. (ist d.) ; sense o! pressure above r. eye (3rd d.) ; on 5th d. burning and pressing pain about eye, especially 1., which also itches, and next m. is inflamed, with huining jerking pam lasting till noon, and then subsiding ; loud tinnitus aurium (4th d.) ; continued pressing in ridge of nose, with frequent snecjing (md d.) ; pressing pain in r. face, between eye and nose, p.m. ; severe preswng in molar teeth aiter 10 p.m., continuing some h. ; dull pain in incisor and eye-teeth ; costive for first ad.; on 3rd m. a scanty stool and at noon a soft one j on 4th a soft stool early, a h. later a diarrhccic, then again a soft stool, all a.ni., and during time frequent ineffective urging ; on 5(b two solt stools, with much flatus ; on another occasion, after repeated doses, had on 3rd d. while riding momentary nausea on shifting of flatus, followed by stool with cutting pains in bowels; strong desire to urinate (9th d.) ; drawing and sticking in whole 1. neck, p.m., for 8 h. ; pres.\ing below I. shoulder, in e.; paralytic pain in sacrum at 10 p.m. in bed, with long-lasting confusion and pain in head (md d.) ; lameness in sacrum, e. in bed (3rd d.); frequent strong cracking in joints and clbow.i;, p.m. ; itching in bend of r. knee (9th d.), paralytic feeling on shin-bone, p.m. ; on 6th d. red ^pot, size of pea, on outer aspect of I. leg, a little below knee, itching excessively, and afterwards burning, succeeded by a second near it, and next m. a third on r. knee. {Ibid.)

3. Dr. Williamson proved md dil. Acute pain in 1. temple, much increased by going upstairs; aching acros-i loins, worse in e. {Ibid.')

4. ii. On April loth, 1834, I made an infusion ot recent unbruised leaves, ^ij to i pint of boiling water. At 3 p.m. I took Jss, then a doses of jj at intervals of ^ h., after \ h. Jij, and at 4.30 ^vj. At the beginning of the experiment the pulse was 63, 6 or 8 beats quicker than usual, probably due to a full meal. No decided eH'ect was noticed at first beyond slight general pricking sensation (as from beat in spring) and increased tendency to sweating. 5, sleepiness and ^ns^tion of warmth through epigastrium, both of which gradually increased. Went to bed and slept for 1 n., awaking diizy, but took tea as usual. The pricking is worse; it is more conspicuous in the scalp ; it is a sensation of coolness with pricking by innumerable minute points at the same time, comparable to the effect of peppermint on the moulh. Sensation of great fatigue in all the muscles, especially when exerted, fi^^( noticed in muscles of mastication, which are excessively fatigued by very moderate exertion. The dizziness increased and a]»o the fatigue. Soon there began a sensation of gradual contraction of the stomach, forcing its contents up into the oesophagus, and a feeling as of a ball rising in the throat, but without nausea. 7, vomiting without nausea set in (with an action like rumination), recurring every 3 or 5 m. for i h., and accompanied with dinmcss of sight. Much bile thrown up towards the close. Muscular prostration was such that I could barely walk across the room. The affection of vision amounted almost to complete blindness when in an erect position. The action of the drug

exactly TMemblcd that produced b/fvtnxram Tiride both on t)a'49^inu«clc% ml itomach. The pulu was not aamoktd t^in until after ch? vomuiog: ic 40 per m., and extivmcl^ wolc and crMpinE, the anery wcming aIowI^ to comf^ct and dilaie. 1 vrai at thi« time silting in a t^xtr, and the KJctn wu motu «iid cool* Secretion of taltva more tree than trom in ordinarj cmetk, but not sa profuse ai from verutrum liride. Scmation 41 if the bo^cU vroiiJd ictf which did nor lupp«SL The vomiting veaied at f, bui the cool tkin, wtak kIow polie^ diaiacM, vad nnucillsr weakneas continued unabated until after 9, I then took some g6<>d «riti«, u»d in I h. vnA 2% well as erer I am* Durinr the expeHmcni then waa ■ tlight pain in ttie fnrthradi which in another pcison kuj^ hate been KTtn, hut f never j^ n arrcre headache from any cauie.

A. April atst I prepared an infusion of the umc itiength of the bruEwti learn, 8.^0 ajn., took Jj. At lo, »Ught vertigo and ^^tirc flow in dilTirTient psfta uf the surface, with increace ofaweating. I tnoa^ht there wv wmc increase ot nrtnr botJi in this and in the Brat experiment. Tbcse sjrmptonMf with itching of %km, itM.it mtiL At 11.15 glow in epigastrium ; fatigue of mtuclesj legv would hardly bar way weight on going upstairs ^ tlKpineia. At 11^35, while l^ing down, the uulve «rt» f 5 |»rr ol, but not sQ wnJt as Wm n* Mi<hU]r, «onie feeling of etidCitenon of Motnacii, luc followed by vomitingf Ate dinner at t.30, Sleeplnev eeocinued till 4., mnd tike ilowness of^pulae nntd after dinner*

f, July 4th.^Began expericncm with tiact. (Iij of recently cut leave to Qj «rt a[cohol)< At 3 and 4. p.nu took 5ij< In about f b. after and daw glow in rpiga»trium with vertigo ud pricking m iikin„B]id acme ecccM ef Jfeteattnc. Vertigo gradually increased. At 5.15, ^ij. At C puhe 4I, itm^gitk MC sllercd. At 6^15 took 5ij ) at 6.30 coD«deriii>le fomnolcncy* At 7.4; alt synaptomx wone, %kin cool, pul«e 3S, weak and irregular, Uneasineu at vtomach, not n^uKa noe yvt eioirtly tame sensation as produced by the infusion. SomnolenC} worse, and cxrea*i« r tatigue of uiukUi on slight exertion. Vision affected, darkoim coming hefoire eyrv every 3 or 5 m., and oftener if in erect posture. Could only take three %tepM^ owuij to TerttgD and exhauAion. Slight pain in forehead. At g p.m. vomited, with the ruminaring sensation mentioned before; then feii a&teep. Woke at 5 and 7 a,tn^ felt well in m., except some frontal unasinett. Whole quantity of tincture talc.cn, \j.

d. Jan. 15th, S a,m.| took »o gr. of coarsely powdered leaJ. At is, 18 ^. mort. All the symptoms resembled tho9e produced in tne other bialsj but the pricktag ol the skin was leis pronounced. At y.^9 took 40 dr, of laudanum, which rapidly relieved all the symptoms^ Feb. i^Tth, took 30 fETi. finely powdvrrd \ the effects werr

just about equaJ to those produced by %t er. of the coarw povrder. Match and.

Began with 10 gr,, intending to continue the dose every 40. for MnQe d., but the effect in z or ^ h. wa« a» great ai that from ao gr. before. I therefore took 5 ST. $ times a d, for 3 d. Some diaphoresis, improremctit of digestion , and iichtn^ of dtin. No other secretion afccted. Similar effecta were agVLin nrcHJuced br preparuica ali^htly differenfly made. Il thould be noticed that witn ktiimui iVe flevling of fatigue precedes the tomiting. (" W,," ia Be/tm Hid, wtd Sttrg, J omit, , x^ 3itl>)

II. PTisomnp, — t. Two c^es of poisoning rsulled £roni eating a pheasant, in the craw of whjch leave* of K» were found,

a. In one, \ h, after meal^ nausea with entire lou of sight j continued retching, and violent pain in crown of head^ extending down cervical verlebrxi coldtic» at eniremities ; pulse imperceptible, and when rctumtng, beating only 40 in m,

h. In second ca&e, peculiar noise on breathing, aA from tpatm of jflotttk j pallor; excessive nausea, with dimnesof fight j violent pain down nack \ coldncu ol cxtrvmities; pulse feeble, and only 40 in m, (SHOEMACia, JUoT.Mr^. ^ d^ff/r. ^r#%^jM/

P- M«)t

• Professor Tully, of Albany, observed the following effects froir

ministered for subacute rheumatism (dJoice not stated), ^ix. : pricking sensati generally, moderate sweatingj wunnth in the stomachj relief of pain, at hilness, then, perhaps, some somnolency, vertigo, and imperfection of vUoik doses, though frequent, were not large, vomiting was not produced. Tntlf

this drug analogous to Rhododendron chrvianth.

-f For Dr. Faust*s proving of K. see Appendix to this

/olnme*

Volume IV — Appendix

KALMIA. (See vol, iii, p. 69.)

I, 8, a. Dr. Louis Faust, att. 20, weight 148 lbs., dark hair vA complexion ; before proving, healthy ; pulse 66 — 70. Commcjicetl proving on July ist, 1875, with tinct. ist d.— Took 4 dr. Neuralgic pain in r. leg below knee j also in r. elbow going to shoulder and then

• See ii, t.

t Dr. Owens stares that he undertook a proving of K. iod. some jrrar* aps*"' elkited this symptom several time*. {Ibid., p. jjs,)

wrist, finally locating itself in elbow. Full dull feeling in the head, feeling all over body as if I had been exposed to a soaking rain, md d. — Took 5 dr. Dull feeling in head continued. Increase of pain in elbow, which again extended to wrist and produced sensation in whole forearm as if it were in a vice. 3rd d, — 6 dr. Symptoms Mme as yesterday, only a little more intense. 4th d. — 7 dr. Scraping sensation in throat all d. which caused desire to cough. Drawing tearing toothache. 5th d. — Took 10 dr. Neuralgia of face. Drawing tearing pain in epigastric region, aggravated by slightest motion, even talking. Nausea. Pain in the vertex and temples, sometimes alternating in these- places. Toothache. 6th d. — ^11 dr. Headache in top of head, shooting to temples. Head feels as if it would burst. Rheumat'c pains all over body, often changing their position, so that they Cannot be localised by description, especially in shoulder, elbow and Ti8t. Feeling of lassitude in limbs as if I had walked a longdistance. P'^h d, — 15 dr. Excessive burning in anus after stool. Stool some- ^lnat harder to-day. Same pains in different parts of the body. 8th ''-' — 20 dr. Stool this m. very hard and large, so that it could hardly ^^•ssanus. Excessive burning in anus after stool. 9th d. — 25 dr. ^ — onstipation continued. No new symptoms. More of those rheu- ^^ -Btic pains in different parts of the body. loth d, — Took 30 dr. — •constipation continued, nth d. — An attempt at stool this m. was *2uccessful, as stool was too hard and too large to pass the anus. ^ ">-^a.m. passed a large hard stool with great difficulty, a.30 p.m. took ^ dr. Sensation of rawness in throat causing constant desire to cough. 1 this point I siuspended the proving for 13 d., as the constipation came so troublesome. It passed off as soon as drug was discontinued, f.^ ,^^ b. Dr. F — resumed proving July 25th. 12th d. — 30 dr. Slight -^ ^^eumatic or neuralgic pains all over body, but of no particular moment, ^^ 3th d. — Took 50 dr. Alternate rheumatic pain in the shoulder and ^^ ^bow of r. arm, finally locating itself in elbow. Dull drowsy feeling ,^ ^ head, which changed to raging headache in temporal and occipital *g'0"' Sensation in the eyeball as if walls and roof of orbit were ^^ressing on it. 14th d. — Wild unpleasant dreams all n. 10 a.m., ^ook 30 dr. Rumbling and feeling of emptiness in stomach as if I had ^aten no breakfast, 2.30 p.m., took 30 dr. 15th d. — Took 70 dr. ^Soon after taking medicine faint feeling, which soon left me, with dizzitiess, 10 a.m., pulse 80. Vertigo, worse towards noon. Lancinating pain in middle of humerus ; darting pains through the ears. 4 p.m., pulse 68. Took jj. Weakness below knees, as though I would fall down. 4.30 p.m., fee! restless, go from one place to another looking for something and don't know what. Nausea ; buzzing before ears. Urine increased but clear. Neuralgic pains in leg along inner side of tibia j this symptom I have felt more or less during whole proving. Pains in ankle joint, very severe at times. 10.30 p.m., pain in temporal region. 11 p.m., drawing sticking pain in hip and sacral region. 16th d. — After retiring last n. severe pain in r. knee, in vicinity of patella. Pain in 1. ankle. Severe backache. Restless sleep. Unpleasant dreams. Awoke at 4.30 this m. with severe headache; after that I could only sleep a few moments at a time, and would awake out

63a

of frightful dreams. Pain through r. leg even to toes. 10.30, wu taken with pain in bowels, which drove me to stool ; stool wm diarrhoeic and passed with slight tenesmus ; soon followed by mujo. 10.30 a.m., pulse 72. Pain in molars, a shooting pain from temples to eyeballs. Dyspepsia. Feeling of anxiety, 4 p.m., pulse 66, took 5J. A gnawing pain in palm of hand, mostly in metacarpo-phalingeaJ articulations. Feeling of lassitude all over body. Irritable, fee! like scolding everybody. lO p.m., took 30 dr. Urine still increased. Pulse 54. J 7th d. — Awoke this m. with full, dull feeling in had, which lasted for an h. after rising. I did not feel like moving. The same peevish feeling as yesterday, g.30, pulse 70. 9.45 a,m., took 70 dr. Soon after taking medicine feeling of heat all over body, with, out change of pulse. Pain in r. knee under patella. 2.30 p.m., ve^ sleepy, almost fall asleep over my books (not because the books do not interest me), cannot concentrate my mind on my books. Pain m neck and all the way down back. Severe pain in patella of I. left i8th d. — After retiring last n. could not sleep for 2 h., restless jnd tossing about in bed. I felt as though I had worked too hard and wi» too tired to go to sleep. 8 a.m., gnawing in epigastrium, wi:h fcelinj as though I had not eaten anything. Stitches in r. hypochondrium. Fluttering of heart; this I had twice yesterday, but did not lay it to the K., but to-day it has attacked me with increased violence, and I can trace it to nothing else; it is accompanied by a feeling of anxiety, I feel as if something dreadful was going to happen to me. 9. iS'-O'i pulse 62, took 70 dr. Same feeling of heat all over body after takinr the medicine as yesterday. Sticking pain in little finger which shot all along ulna. Headache in temple shooting into eyeball. Constant pressure in eyes, can hardly keep them open at times. Frequent erections without desire and coming on spontaneously. After having studied, got up from my chair but was too dizzy to walk. 4 p.m., took ro it. Slight fluttering of heart, 9,30 p.m., pulse 64. 19th d. — Took 85 dr. Heat all over body as before. 10.30 a.m., very sleepy. One side « the nose has been occluded for 3 d. Felt yesterday as if I had what is commonly called a cold in the head. Gnawing in stomach as thougli I had had no dinner, which causes headache and nausea, 4 p.m., too* 60 dr. Cutting pain on r. side of tongue, relieved by biting on it. Rheumatic pains in hips and down legs. 20th d. — Awoke this m. with a very painful pressure over the eyes, and temporal headache, which was temporarily relieved by cold water. Pain in the interscapul'^ region. Pulse 70. Stool normal, but burning in the anus after stool., Headache only on r, side. Pain over r. eye. 3 p.m., feel very drowsy' Pain in shoulder lasting 15 m. Pain in whole length of the back. The headache has continued from this m. Pain in stomach with' sensation as if something was tearing the walls from their connections, 2 1st d. — I did not feel like going to my books this m. Headache whicli last 10 m., then leaves me a few m., but only to return again. Sticking pain and weakness in wrist joint, almost disabling me in writing. Headache in occiput with pain in neck. 8 a.m., pulse 68 ; 10, pulse Bo. Vertigo when getting up from a seat. Rheumatic pains in ). leg p.«n.» which lasted until I went to bed. 22nd d. — Pain in neck has not ret

me. Feel very languid this m., with an occipital headache.

9.30 a.m., toolc 3j. 10, pulse 84.; great heat all over body. Cannot

study. Restless, want to leave the office, but don't know where to

go. 10.30, took another 3J. A bruised feeling ail over body. Pain

in neck increased, mostly in 7th cervical vertebra. Sensation of fulness

in head. Feel as though I would not like to be spoken to. Don't

feel like going to the office. Took a book at home but could not fix

my mind on it. Vertigo; a hungry feeling in the stomach; do not

feel so bad this afternoon (3 p.m.), but there is still stiffness of neck,

and rheumatic pains in leg. Soreness of hip. Took 3J. Pain in region

of submaxillary glands shooting to parotid. Feel very tired, can hardly

walk. 23rd d. — Felt very restless after retiring last n., could not

sleep. Awoke this m. at 4 ; could only sleep a few moments at a time ;

would awake out of annoying dreams. 8 a.m., 5J. Headache on 1.

side from temple to occiput. 7 p.m., took gj. 24th d. — Awoke this

m. with headache, relieved by cold water. 9.30 a.m., took giss.

Same pains which have so often been repeated in head, neck and back.

Sticking pains in 1. lung, under 3rd and 4th ribs, causing dyspnoea.

Sleepiness. Dulness of head. Don't feel like studying. Chill (this

symptom was felt several times before, but attributed to the weather;

now I find I have a real chill). Before retiring, itching and burning

all over body, as if I had been stung by mosquitoes, 25th d. — Same

empty feeling in stomach as though I had had no breakfast. Alternate

pains in shoulder, hip, and knee joints. Pressure in eyes, soreness of

edges of lids. Pulse 54; feel very languid. Distress in stomach after

dinner as though I had overloaded it, also thirst, though I have not

eaten anything to cause either symptom. 3 p.m., very sleepy, fall

asleep over my books. Feel very tired all e., almost too tired to record

my symptoms. Took no medicine to-day. 26th d. — Rheumatic pains

in elbow and leg. Some headache continued all d., same as before.

Same sleepiness, though not so well marked as before ; also slight chills

over whole body. Discontinued proving.

e. On a subsequent occasion, resumed trial of tinct. 1st. d. — Took at 3.15 p.m. 30 dr., at 4.15 and at 7.30 40 dr. Pain between shoulder-blades, coming up over head into temples, not affecting the eyeballs. Scraping in throat. Rheumatic pains in shoulder and scapula. Feel like stretching myself. After taking the medicine, a heat all over the body, and flushed face, but no increase of pulse. 2nd d. — 8 a.m., took 70 dr. Pain in epigastrium. Pain under angle of jaw. Slight burning during urinating. 10.30 a.m., took 90 dr. Dull occipital headache. Pain in hypochondriac regions. When going down stairs, sensation as if tendon of quadriceps extensor would give way and I should fall down stairs. Pulse irregular. Headache in occiput with pain in neck. Soreness of edges of lids. 3rd d. — Awoke this m. with pain in shoulders; they felt as if they had been bare all n. Pain in I. knee. Pain in sterno-cleido-mastoid muscle. Pain in teeth as if nerves had been laid bare. Sticking pain in lumbar region, worse on moving. Pain deep in 1. side of nose. Pain and pressure in eyes. Dull headache in occiput and temples. Sticking pain in index finger of 1. hand. Dull headache which cannot be located, it has con-

tinued all afternoon and e., at first it seems to be in one place and again in another, but is most marked in parts back of forehead. 4th d. — Pain in lumbar region. Urine increased. Pain in r. ear 5th d. — Took 100 dr. at 8, and 300 dr. at 10 a.m. Cutting paint ia bowels followed by a loose stool, which relieved the pain. Darting, aching pain in jaws. Pain in r. testicle in m., which went to 1. ia afternoon. Face flushed with the headache. Pain in lower incisor teeth. Pains about umbilicus. Pain in ball of great toe of 1. fboc^ causing me to cry out. 6th d. — Took 150 dr. A feeling d qualmishness this m. Heaviness of eyes. Same headache continued as before, dull and hard to locate. Pulse 85. Same pain in ball ci

treat toe of 1. foot in e. ; this I have had for 3 successive e. 7th d.— Trine increased. Pains in shoulders, especially r. 8 p.m., pulse ^ Head hot. Face flushed. Headache, mostly in temples and fore* head, which was relieved by pressure. Qualmishness of stomach. Neuralgia of face, pains were transient but severe. Took no medicine to-day. 8th d.— Took 50 dr. Pain in the upper and lower r. moUtl and bicuspids, coming from malar bone. Pain in ball of r. thumb; Sticking pains in glans penis. Aching and heaviness of eyes. Sticb ing pains in both limbs and in r. elbow. [Communicated.)

1. £. C. Strader, xt. 21, weight 182 lbs., dark hair and oonu plexion, commenced proving Nov. 23rd. 1st d. — Took 15 dr. o( tinct. Heat in 1. shoulder extending to forearm, and to tips of Angen, Pain in r. shoulder. Sticking pain in thigh extending to knee. Paini in hands and in all the joints. Pain in little finger extending along wrist and ulna to elbow. 2nd d. — 15 dr. Palpitation of heart aM oppressed breathing, with anxiety. Pain in little finger, forcibly flexing it. Sharp pain in lumbar region. Frequent desire to urinate Stitches in soles and toes, also in both upper and lower extremities^ Alternate flashes of heat and cold all over body. 3rd d.— Took 75dr« Pain in supra-orbital region extending to occiput. Stitching pain in I. elbow-Joint. Sticking pain in r. shoulder-joint. Neuralgic pains ia 1. upper molars and bicuspids. 4th d. — Severe frontal headache lasting 2 d. ; could not concentrate my mind on my books. 5ch d. — Same headache. Took 50 dr. 6th a. — The headache has continued until now, incapacitating me for study. Had to stop taking the medicine on account of it. {Ibid.)

2. B. £. Mead^ xt. 23, weight 150 lbs., dark hair and complexion, commenced Nov. 24th. ist d. — 30 dr. of tinct. Pain in r. shoulder. Drawing pain in little finger of 1. hand, extending up arm along ulna. Face flushed. Surging of blood to head and as it were against cheeks, 1. cheek is uncomfortably hot. Pain in lumbar region ; frequent desire to urinate. 2nd d. — 50 dr. Body feels hot all over, then again cold. Headache in front part. Pain in lower extremities. Frequent (30— 40 m.) desire to urinate, urine feels warm as it passes, small quantitiei passed at a time. 8.30 p.m., 75 dr. Sticking pain in all joinu. Palpitation of heart. Headache in all parts back of forehead. Body feels alternately cold and hot. Limbs feel as if they had been beaten Oppressed breathing. 3rd d. — 50 dr. Headache. Cannot fix mj mind orv my boo\K.%. ^ucVaw^ ^'i.Nw^ \tv lumbar region. Paint in

extremiries, both upper and lower. Feel anxious and uneasy. 4th d. •^Frontal headache. Limbs feel as if they had been beaten. Urinate about once an h. 5th d. — This headache continued, with pains in different parts of body. 6th d. — Just as the former prover gave up the proving I had to do so, and also because of the persistent headache, which stopped when I discontinued taking the drug. {liiil.)

II. E. P. Macomber, weight 135 lbs., light complexion and hair. Took at first 3 doses of 3rd dih, 10 dr. each, when I began to have effects. Dull heavy headache, confined to forehead and temples, especially marked in forehead, aggravated bv mental effort, with a pale face. Shooting pains in jaws a^T teeth. Pulse irregular. Palpitation of heart. On walking slowly up stairs fluttering of heart. Irregular pulse, aggravated by mental effort. When leaning forward to write, violent palpitation of heart. Darting pain in upper cervical vertebrs. Shooting pains in r. shoulder. Pain m 1. arm, extending from wrist to elbow. Ubid.)

IIL Obstrvatitns on animak.^i. In the latter part of the winter and in the early spring cattle, desiring something green, eat this shrub, which is very poisonous. The first symptom of its action is intense thirst, the animal drinking all it can bear ; thereupon follows trembling, weakness, staggering and jerking, abdomen being full of wind. This is soon succeeded by clonic spasms, at intervals of 15—20 m., which increase in severity till they become most violent convulsions. During the intervals the animal appears rational, and will try to get up and walk about, but in the effort falls into another spasm. Eyes become fixed, pupils turned upwards, head drawn backward, limbs rigid, abdomen bloated and bowels loose. If the animal recovers, it is apt to be in a state of prostration for a week or more, and seldom gets over the effects under 3—4 mos., during which time it is weak and nervous, and walks as if intoxicated, tottering as if unable to control the use of its limbs. (Meadow, Southern Journ. of Htm., April, 1890.)