Digitalis

Digitalis purpurea, L.

Natural order , Scrophulariaceæ.

Common names , Foxglove; (G.) Fingerhut.

Preparation , Tincture prepared from the leaves of the second year of the plant.

Authorities.

1 , Hahnemann, Chr. Krn., 3, 230; 2 , Becher, ibid.; 3 , Franz, ibid.; 4 , Gross, ibid.; 5 , Hornburg, ibid.; 6 , Jahr, ibid.; 7 , Langhammer, ibid.; 8 , J. Lehmann, ibid.; 9 , Meyer, ibid.; 10 , Piepers, ibid.; 11 , Rückert, ibid.; 12 , Stapf, ibid.; 13 , Teuthorn, ibid.; 14 , Trinks, ibid.; ( 15 to 51, authorities quoted by HAHNEMANN ); 15 , Baidon, Edinb. Med. and Surg. Journ., III, 271, "statement from observation;" 16 , Baker, Med. Trans. of Lond. Coll. of Phys., III, art. 17, "effects of Digitalis in a case of anasarca;" 17 , Baylies, Pract. Essays on Medical Subjects ("not obtainable"); 18 , Beddoes, Med. Facts and Obs., V, art. 2, "from an overdose;" 19 , Boerhaave, Hist. Plant, 1731, p. 308, "observed effects;" 20 , Drake, Med. and Phys. Journ., IV, 521, "effects of Digitalis when given for phthisis;" 21 , Edinb. Med. Comm., X, 358, "from overdosing;" 22 , Gremler, in Rust's Mag., XXV, 578, "from overdosing;" , Guibert, Gaz. de Santé, 1826, "effects of Digitalis in a case of enlarged heart;" , Haller, in Vicat's Mat. Med., I, 112, "statement from authors;" , Henry, Edinb. Med. and Surg. Journ., VII, 148, "from overdosing an ascitic patient;" , Horn, Neues Archiv, I, 504 ("nothing about Digitalis here"); , omitted (see Nos.

52 to 62 ); 28 , Journal de Chimie, 1827, p. 593, "from an overdose;" 29 , Kinglake, in Beddoes ("nothing from him found here"); 30 , Kraus, in Hufeland's Journ., v. 3, 182, "as Baker;" 31 , Kurtz, in Jahn's Med. Conv. Bl., 1830 ("not obtainable"); 32 , Lentin, Beobacht., 1774, p. 167, "from an overdose;" 33 , Lettsom, Mem. of Med. Soc. of Lond., II, art. 16, "effects of Digitalis when given to dropsical patients;" 34 , Maclean, Med. and Phys. Journ., II, 119, "effects on patients;" 35 , Mangold, in Horn's Archiv, III, 1, 141 ("not obtainable"); 36 , Mayer, Richter's Chir. Biblioth, V. 531, "effect of Digitalis given for mammary scirrhus;" 37 , Monro, Samml. f. pr. Aezt., XIII, 288, "effect of Digitalis given for dropsy;" 38 , Mossmann, I, Essay on Scrofula, "not obtainable;" 39 , Mossmann, II, Med. and Phys. Journ., III, 13, "effects of Digitalis given in pneumonia;" 40 , Müller, in Nasse's Zeitsch. f. Anthr., I ("not obtainable"); 41 , Neumann, in Hufel. Journ., LV, 58, "effects of Digitalis in phthisis;" 42 , Penkivil, Med. and Phys. Journ., III, 315, as Neumann; 43 , Percival, Med. Facts and Exper., I, 113, "effects of Digitalis given in hydrocephalus;" 44 , Quarin, Animadv. Pract., p. 118, "nothing about Digitalis here, but most of his symptoms cited in Baylis's Bibl. de Therap., III, 320, effects of Digitalis given for scrofula;" 45 , Remer, Annal. d. Kl. Aust., I, "not obtainable;" 46 , Sackreuter, Annal. d. Heilk., 1811, "not obtainable;" 47 , Schiemann, Diss. de Dig. Purp., 1786, "not obtainable;" , Schriven, Med. and Phys. Journ., III, 207, "from overdose;" , Troschel, Hufeland's Journ., 1829, p. 127, "a translation of Guiberth's case;" , Warren, Lond. Med. Journ., VI, 2, 145, "from overdose;" , Withering, Account of the Foxglove, 1785, effects of Digitalis observed on patients; ( to , Jörg's provings, Materialen Zur Heilmittellehre); , Güntz took 1/4 of a grain of the leaves with 2 grains of magnesia, afterward 1 gr. with magnesia, and afterward 2 grs. with magnesia; , Heisterbergk took 1/4 to 1 gr. with 4 grs. of magnesia; afterwards 2 grs without magnesia, afterwards 2 grs without magnesia, afterwards 2 1/2 grs. with magnesia; , Knesche took 1/4, 1/2, 3/4, 1, 1 1/2, and 2 grs., each with magnesia; , same prover took of an infusion of 1 scruple of leaves to 4 ounces of water, one spoonful, afterward 12 to 25 drops of the tincture (1 part leaves to 6 parts of spirits); , Seyffert took 1/4, 1/2, 1 1/2, and 2 grs. with magnesia; , same prover took infusion and tincture; , Otto took 1/2 gr. first day, 3/4 gr. second day, each with magnesia, 1 1/4 grs. third day, 1 1/2 grs. fourth day, 2 grs. fifth day, 2 grs. seventh day; , Siebenhaar took 1/2 to 1 1/4 grs. with magnesia; , same prover took 1/2 to 3 grs. without magnesia; , Jörg took 1/4 gr. with sugar first day, 1/2 gr. second day, 3/4 gr. with magnesia fourth day, 1 gr. in water fifth day; , Mad. Ch. took 1/4 gr. with sugar first day, 1/2 gr. second day, 1/2 gr. with magnesia fourth day; , Schrön took 1 gr. of powder in water first day, 2 grs. second day, after three days took 3 grs; , same prover, after waiting a month, took 1/2 gr. three times a day for three days ( ); , Baehr took tincture, 10 drops at 11 A.M.; [Before making his provings he kept records, showing normal micturition five times a day, seldom four times; daily amount of urine averaged 1075 cubic centim.; sp. gr. averaged 1025, high probably in consequence of small amount of liquids taken; pulse averaged, mornings in bed, 56, during day, sitting 61, standing 66.]

64 b , same prover took, first day, 10 drops at noon, second day, 10 drops evening, fourth day, 15 drops at noon; 64 c , first day, 15 drops noon, second day, 18 drops evening, third day, 20 drops evening; 64 d , first day, 1/2 gr. of powder forenoon, second day, 1/2 gr., third day, 1 gr., fourth day, 1 gr., fifth day, 1 gr., sixth day, 1 1/2 grs.; 64 e , first day, 1 1/2 grs. forenoon, 1 gr. evening, second day, 1 1/2 grs. forenoon; 64 f , one dose of 1 1/2 grs.; 64 g , first day, 32 drops tincture morning, 20 drops evening, second day, 20 drops morning, third day, 30 drops evening; 64 h , one dose, 2 1/2 grs., in morning; 65 , Dr. Hutchinson (Joumides, Progres d. Sc. Med., 1821, from Dr. Black's article in B. J. of Hom.), took repeated doses of 60 drops until 420 drops were taken in three days; 65 b , same took 10 to 70-drop doses till 2220 drops were taken in sixteen days; 65 c , same took 12 to 40-drop doses every eight hours till 1694 drops were taken in fourteen days; 66 , Dr. Francis Black took tincture, first day, 10 drops, second day, 10 drops at 10 A.M. and 2 P.M., fourth day, 20 drops, fifth day, 25 drops, seventh day, 30 drops, fourteenth day, 25 drops at 11 A.M., and 15 at bedtime, sixteenth day, 36 drops at 11 A.M. and 20 drops in evening; 67 , Dr. L. took 10 to 36 drops daily for six days, in all 172 drops (only one symptom, headache); 68 , Dr. K. took tincture several days, 10 to 60-drop doses (only one symptom, urine); 69 , a friend of Dr. Black took one dose of 20 drops of tincture; 70 , Dr. Saunders took 15 drops night and morning for three days, 25 drops fourth day, 50 drops seventh day; , Purkinje, Beob. und Vers., 1825 (Frank's Mag., 4, 154), took 3 grs. of aqueous ext. daily for four days; , same took an infusion of 2 drs. of leaves to a pint of water; , Hammond, proving on a man, aged 25, with tincture, 20 min. three times a day for three days, Am. J. M. Sc., 1859; , Gourvat, anaphrodisiac action (Gaz. de Paris), Phil. Med. Times, 3, 463; , Cattel, symptoms compiled, B. J. of Hom., 11, 170; , Homolle et Quevenne, Mémoire sur la Digitaline et la Digitale, 1854, proving with powdered Dig. (in pills), 0.20 to 0.30 grms. daily for eight days; , Oulmont, poisoning of a woman, aged 22, by a teaspoonful of the tincture taken for palpitations, Lond. Med. Gaz., 2, 989, 1851; , De Colleville, poisoning of a woman, aged 68, by an infusion of 15 grammes of dried leaves, taken for œdema of lungs when nearly convalescent (Journ. de Méd. de Bordeaux), Lond. Med. Gaz., 1849; , Cabaret, a man, aged 55, took half a glassful of the juice of Dig. for intermittent fever, B. J. of Hom., 1, 411, from Oppenheimer's Zeit., 1843; , Quebec Daily News and P. J., Feb. 1865, B. and F. Med.-Chir. Rev., 1865, poisoning of three men by the tincture; , Perrin, poisoning of a young man by decoction of the leaves, Gaz. des Hôp., 1874, p. 925; , Mozel, fatal poisoning of a woman, aged 22, by an infusion of 3 1/2 grammes of the leaves, Gaz. d. Hôp., 1864; , A. Taylor, fatal poisoning, by 6 ounces of a decoction of the leaves, from Tardieu Empoisonnement, p. 798; , same, fatal poisoning of a young man by a decoction; , Causse, poisoning of a pregnant woman by the juice, Ann. d'Hyg., 1859; , G. Wilson, poisoning of a young man by two teaspoonfuls of a very strong infusion for a sore throat, Lond. Med. Gaz., 1864; , Edward, poisoning by an infusion of 2 ounces of the root, Lancet, July, 1849; , Fogo, poisoning of an asthmatic patient by 1 ounce, N. Eng. Med. J., 12, 81 (from Ed. M. J., No, 72); , Brughmans, general effects of 0.30 to 0.40 centigr. of powder for five or six days, from Homolle and Quevenne, Mémoire sur la Dig.; , Vassal, effects on a woman, aged 44, of doses of 2 centigr., Diss. sur la Dig., p. 79, from Homolle and Quevenne; ( , , , omitted;)

93 , Dr. Lewis Burwell, Inaug. Diss., Philadelphia, 1805, having fasted and taken moderate exercise till 10 A.M., took 1/4 gr. of powdered leaves, repeated after two hours and a half, and several times with similar results; 94 , Dr. Barton (quoted by last authority), several persons took Dig. unintentionally; 95 , Lembke, proving with 1/4 gr. of powdered leaves, first, sixth, and thirteenth days, 1/2 gr. twenty-second and twenty-eighth days, 3/4 gr. forty-seventh day, and 1 gr. seventy-ninth day, N. Z. f. Hom. Kl., 2, p. 171.

MIND

• Emotional.
• Secretive insanity, with obstinacy; he tries to escape, 1.
• Delirium (third day), 84.
• Slight delirium at night, with some agitation (third day); rather violent delirium in the night (fourth day); so delirious during night that it was necessary to use restraint (fifth day), 76.
• Irrational talking, with uneasiness, at night, 30.
• I was in a state bordering on drunkenness (second day), 65.
• Intoxicated feeling, 81.
• Excessively intoxicated, 94.
• Many lively fancies, 3.
• Great desire to be alone, 10. [10.]
• Disinclination to talk, 5.
• Continual sighs and groaning (fifth day), 76.
• Gayety bordering on intoxication, with debility, 89.
• Peaceful, quiet mood (curative action), 3.
• Great depression, 74.
• Dejection, 87.
• Dejection of mind and apprehensiveness, 51 . [Not found. -Hughes.]
• Sadness, with feeling as though he were very sick; all objects appear to him as to one sick with a fever, 1.
• Great sadness and dejection throughout the whole proving, 6.
• Weeping sadness about many things which have disappointed him, 1. [20.]
• Gloominess and ill-humor, 5.
• Anxiety, as though he had done wrong, 8.
• Anxiety, with great dread of the future , worse about 6 P.M., with sadness and weeping, which bring relief, 6.
• *Great anxiety, 30.
• Internal anxiety, like pangs of conscience, as though he had committed a crime, or expected to be reproved, continuing nearly three months, 6.
• [Loss of courage], 42 . [On account of the apparent inefficacy of the medicine. -Hughes.]
• *Fear of death, 1.
• Apprehensiveness, as if rising from the upper abdomen, .

HEAD

• Confusion and Vertigo.
• Confusion of the head, 1 ; (second and third days), 58.*
• Confusion of the head like an intoxication, 56.
• Confusion of the head, with some confusion of the mind (fifth day), 61.
• Confusion of the head, which causes difficulty in thinking, and gradually changes into a pressive pain (seventh day), 58.
• Confusion of the head, which gradually became a pressive pain, extending from the vertex over the whole head, with the same sensation in the eyes as on the previous day, with small and slow pulse, somewhat increased secretion of urine, and for half an hour very violent irritation of the genitals (fifth day, half an hour after 2 grains), 58. [60.]
• Transient confusion of the head, not amounting to vertigo (third day), 60.
• Slight confusion of the head (first day), 58.
• Slight confusion of the head, becoming a pressive headache (second day), 62.
• Slight confusion of the head, which after an hour changed into a pressure in the occipital region; this continued with intermissions till towards noon; while the brain was affected in this way I noticed that external objects frequently presented themselves in a false light; I did not actually see double, but not in a right light (first day), 61.
• *Vertigo, 33, 34, 42, 44 , etc.
• Vertigo, so that she fell down while ascending steps, 42.
• Vertigo, with anxious sensation as though faintness would occur, while standing leaning against a chair (after two hours), 64f.*
• Vertigo, on rising from sitting, and noticeable weakness of the limbs (second day), 63.*
• Vertigo, with dimness of vision, disabling her from going down stairs (after three hours), 81.
• Vertigo, with trembling, 20 . [After each dose. -Hughes.] [70.]
• Slight vertigo, lasting twenty minutes (after ten minutes), 52.
• Slight and transient vertigo, very soon, 56.

EYE

• Objective.
• Violent inflammation of the eyes, 1.
• Reddened eyes, with painfulness, especially in the evening, for five days, 10.
• Eyes somewhat red, more sensitive than usual to the impression of light (second day), 65.
• Eyes dim and weak (fourth to sixth day), 62.
• Subjective.
• Burning in the eye followed by a small pustule, with a small areola of inflamed vessels in the periphery of the cornea towards the inner canthus of the right eye (fourth day), 71h.
• Brow and Orbit.
• Intense fixed pain over right orbit (after six hours), 76. [160.]
• Burning pain in the right supercialiary ridge, with dimness of sight, as from a veil, 9.
• Pressive pain in the right supercialiary ridge towards the external canthus, 7.
• Throbbing pain in the orbits, 34.
• Lids.
• Inflammation of the meibomian glands, 1.
• Swelling of the lower lid, which makes looking down difficult, 1.
• Agglutination in the morning, followed by weakness of the eyes, 10.
• Heaviness in the lids, in the evening, with inability to hold them open, 10.
• Smarting, burning in the external canthus, 6.
• Painful scratching in the inner canthus as from coarse dust, 5.
• Sore pain in the margins of the lids, on closing the eyes, in the evening, in bed, 11.
• Lachrymal Apparatus. [170.]
• Lachrymation, more in the room than in the open air; the eyes are dim, hot, full of red vessels, with pressive pain and hardened mucus in the canthi, 12.
• Biting lachrymation, 1.
• Watery discharge from the eyes, 51.
• Conjunctiva.
• Inflamed conjunctiva, 74.
• Conjunctiva of the red, and lids red, .

EAR

• Objective.
• The glans behind the ear are painfully swollen, 10.
• External.
• Drawing pain beneath the right mastoid process, relieved by pressure, 3.
• Some stitches behind the ear, 13.
• Jerking in the outer and inner ear, 1.
• Internal. [230.]
• Feeling of great fulness in the ears, as if they were suddenly stopped, attended with a flush of heat over the face, lasting two of three minutes, recurring frequently, especially after excitement (fourteenth day), 66.
• Pain in the ear as if it were constricted internally; he hears the pulse in it, 3.
• A tensive pressure in the left ear, 12.
• Hearing.
• Sudden obstruction of the hearing, with ringing in the ear, 6.
• Tinnitus aurium (after six hours and second day), 76.
• Ringing in the ears, 74 ; (soon), 77.
• Hissing as from boiling water, in both ears, 13 . [Digitalis has not seldom cured dullness of hearing, with noises as of boiling water in the ears in cases where it was in other respects homœopathic. -Hahnemann.]*

NOSE

• Objective.
• Much sneezing, without coryza (first days), 6.
• Awakened three times during the night from a quiet sleep, by violent sneezing, which seemed to start from the stomach and rise up as a slight nauseous sensation until it affected the nerves of sneezing (first night), 71b.
• Coryza in the morning, with stoppage of the nose, 7. [240.]
• (Constant, very violent coryza, mostly with loss of smell, with catarrh of the larynx and trachea, and expectoration of greenish mucus, without cough, during the whole proving), 64d.
• Stooped coryza in the evening and night, fluent during the day (twentieth day), 6.
• Fluent coryza with much sneezing, followed by stoppage of the nose, 10.
• Epistaxis of bright blood from both nostrils (after one hour), 13.
• Subjective.
• Pain across the root of the nose, 41 . [With vertigo. -Hughes.]

FACE

• Objective.
• Expression of extreme prostration.
• Expression of the face remarkably sickly (second day), 61.*
• *Face pale, 74 ; (soon), 77, 85 , etc.
• Paleness of the face, 31 . [Not found. -Hughes.]
• Face pale, with a greenish, livid tinge (second day), 76. [250.]
• Face remarkably pale (after four days), 84.*
• Face livid (seventh day), 78.
• Convulsions of the left side of the face, 38.
• Subjective.
• Remarkable heat and redness in the face, lasting half an hour, 95.
• Cheeks.
• Swelling of the cheek from the ear to the corner of the mouth, painful to touch, and with eruption upon it, 10.
• Cramp beneath the right zygoma, on moving the lower jaw, which on biting, became spasmodically drawn upward, 3.
• Paralytic drawing beneath the left zygoma, in front of the ear, 4.
• Cramplike drawing pain in the zygoma, disappearing on pressure, 3.
• Lips.
• Swelling of the lips, 25.
• Swelling on the inside of the lower lip, without pain, 1.
• Chin. [260.]
• Stitches in the lower jaw, 1.

MOUTH

• Teeth.
• The front teeth are painful, 12.
• Pulsating toothache in the left lower eyetooth, in the evening, in bed, lasting half an hour; this symptom was certainly caused by Digitalis, since I have never in my life suffered from toothache, and my teeth are quite sound (third day), 61g.
• Tongue.
• Tongue coated for several days, 1.
• Tongue slightly coated, 81.
• Tongue pale (second day), 76.
• *Tongue white (after four days), 84.
• Tongue coated white, in the morning, 7.
• Tongue covered with a white coat, and slightly swollen (second day), 65.
• Tongue covered with a yellow coating, and considerably swollen (third day), 65. [270.]
• Swelling of the tongue, 25.
• He bites his tongue, 74.
• General Mouth.
• Offensive odor from the mouth, 1.
• Mouth moist and thick (first day), 65.
• Dryness in the mouth, 95.
• Dryness of the palate and pharynx with the nausea (second day), 63.
• The mouth is very soft and rough, as if covered with velvet, 13.
• Stitches in the posterior portion of the palate, and in the beginning of the throat, not noticed on swallowing, 11.
• Soreness of the mouth, fauces, and œsophagus, 19 . [Ascribed by the author to the acrimony of the plant. -Hughes.]
• Scraping, raw feeling in the palate, 12. [280.]
• Roughness of the palate, as after too much smoking, 3.
• Saliva.
• Quantity of saliva increased (fifth day), 65c.
• Increase of the salivary and urinary secretions (after twelve hours), 65.
• Accumulation of saliva, 1, 22, 51.

THROAT

• Tenacious mucus in the throat, which is loosened by coughing, 10.
• Dryness of the throat, 41.
• Spasmodic constriction of the throat, 32 . [Not found. -Hughes.]
• Sore pain in the throat, on swallowing, 6.
• Sticking sore throat, even when not swallowing, 1.
• Fauces, Pharynx, and Œsophagus. [300.]
• Dryness and scraping in the fauces, 95.
• A peculiar sensation in the fauces, as if the walls of the pharynx were swollen, or as if they were constricted by swelling of the tonsils (fourth day), 61.
• Soreness of the fauces and posterior nares, especially painful in the morning and evening, for several days, 6.
• Scraping in the pharynx (third day), 58.
• Scraping and slight burning in the pharynx, soon (second day), 58.
• Scraping in the œsophagus, soon (second day), 62.
• Scraping in the œsophagus, with rawness in the air passages, the latter continuing the whole day (second day), 61.
• Sharp irritation in the œsophagus, burning and scraping (fifth day), 61.
• Swallowing.
• Difficulty of swallowing, continuing six day, 78.

STOMACH

• Appetite.
• Slight increase of the appetite (fifth day), 63b. [310.]
• Painful feelings of hunger (after twelve hours), 63.
• At short intervals, a painful feeling of hunger (eight and ninth days), 63b.
• Longing for bitter food, 2.
• Appetite less than usual (seventh day), 58.
• Appetite slight, is immediately satisfied, 12.
• Appetite light, 74.
• Appetite for dinner diminished (seventh day), 64d.
• No relish for food, and indigestion when it was taken (ninth day), 65b.
• *Loss of appetite, 40.
• Loss of appetite, with clean tongue, 42. [320.]
• Loss of appetite, with great emptiness of the stomach, 29.
• He ate his usual meal without appetite, thinking thereby the sensation of nausea would be relieved (after four hours), 71b.
• Thirst.
• *Thirst, 41, 74.
• Much thirst (second day), 65.*
• Urgent thirst, 81.*
• Excessive thirst, caused by great dryness of the mouth and pharynx; this thirst tormented him the whole night; was not quenched by copious draughts of beer and water (after 3 grs.), 63.
• Extremely thirsty ; desire for cold drinks (third fourth, and fifth days), 76.*
• Violent thirst and dryness of the mouth, 74.
• Thirst for sour drinks, 13.
• Eructations and Hiccough.
• Eructations, with violent hunger, after dinner, 53. [330.]
• Eructations, without either nausea or inclination to vomit (after 1 1/2 grain, pure), 53.

[Not found. -Hughes.] [430.]

• After dinner, dull pain and distension of the stomach; felt as if I had eaten too much (fifteenth day), 66.
• Stomachache (eight day, while taking), 75.
• Pressure in the stomach, as from a heavy weight, on straightening up the body, 3.
• Pressure in the stomach and copious secretion of saliva two hours after disappearance of the vertigo (second day), 63.
• Frequent pressure in the stomach and upper part of the abdomen, 6.
• Constant pressure on the stomach, 95.
• Slight pressure in the epigastric region (after one hour, first day), 63.
• Some pinching pressure in the stomach, by paroxysms (after half an hour), 64.
• Cutting pressure in the pit of the stomach, with nausea in it, 4.
• After eating, the food presses in the pit of the stomach while sitting, not while standing, 3. [440.]
• Slight cutting pain in the stomach (second day), 62.
• Pinching stitches in the pit of the stomach, unaltered by respiration and aggravated by touch only when standing, not when sitting, 4.
• Soreness at the epigastrium, 74.
• Epigastrium rather painful on pressure (after sixth day), 84.
• Extreme sensitiveness in epigastric region, producing frequent deep sighs (second day), 76.*
• Suffered much after dinner from severe bruised pain in the epigastrium and over the sternum, with feeling of languor and indigestion, going off on taking a little weak tea (fourteenth day), 66.

ABDOMEN

• Hypochondria.
• Anxiety, tension, and constriction in the hypochondria, 1.
• Pressure in the left hypochondrium, 6.
• Constant stitches in the left hypochondrium, with sensation as though the parts thereabout were asleep, 3.
• Pain, as if everything internally were torn, in one spot, beneath the third left false rib, 3.
• Umbilical. [450.]
• Tearing pains about the umbilicus in the morning, 1.
• Burrowing pressure and sticking in the abdomen, just above the umbilical region, 4.
• Dull, almost pinching stitches in the right side, above the navel, while eating, 4.
• Sharp stitches in the umbilicus, 4.
• Some sticking tearing in the umbilical region while walking, 3.
• General Abdomen.
• *Unusual fulness of the abdomen (fourth day), 58.
• Abdomen strongly contracted upon the intestines, and very hot, dry, and rough to the touch (third day), 65.
• Abdomen felt hard (second day), 76.
• Noises in the abdomen, without sensation of flatulence or emission of flatulence, 2.
• Rumbling in the abdomen, without colic, 53. [460.]
• Movings in the intestinal canal, with slight colic (after two hours); these pains afterwards extended to the lowest portion of the abdomen, into the pubic region, changing into a pressure and dragging, extending down through the pelvic cavity and into the testicles; after an hour these pains and dragging sensations had disappeared, but in their place occurred frequent urging to urinate, with itching irritation in the glans penis, lasting until into the afternoon (first day), 61.
• Audible movings of flatulence about the abdomen, with rumbling and gurgling and a feeling as if bubbles of air were moving along the colon, 6.
• Flatulence and emission of flatus, 11.
• Profuse emission of flatus the whole afternoon (fourth day), 61.
• Intestinal pains (third day), 65.
• Pain in abdomen, 77.

[Original corrected by Hughes.]

• Colic, 83.
• Colic-pains in the abdomen, with rumbling and gurgling, for half an hour, 1.
• Seized with very violent colicky pains, immediately followed by sudden evacuation of liquid stool towards evening (sixth day), 66.
• Pressive colic in the upper abdomen, paroxysmal and cramplike, 6.
• Colic more tearing than sticking precedes the diarrhœa-like stool in the morning in bed, 1.
• Harassed with tormina after going to bed, which did not abate before three o'clock A.M. (fifth night), 70.
• On moving, the abdomen is painful, as if ulcerating, though not on touch, 3.
• Hypogastrium and Iliac Regions.
• Movings about, gurglings and pressure in the lower abdomen, 4.
• Gripings in the lower abdomen, as from a purge, 9. [500.]
• Very violent cutting in the lower abdomen by jerks, 95.
• Jerklike tearing from the moons veneris towards the left groin while leaning the body backward, 3.
• Frequent gnawing, colicky pains in the lower part of the abdomen (from a half to one hour after taking Digitalis), 66.
• Sore pain in the left abdominal ring, as if a hernia would protrude, 1.

RECTUM AND ANUS

• Urging to stool, 5.

STOOL

• Diarrhœa.
• Diarrhœa, 51 ; (after fourth day), 84.
• Diarrhœa, consisting of faces mixed with mucus, preceded by colic, at one time pressive, at another cutting, which always disappears on going to stool (after six and eight hours), 2.
• Diarrhœa, preceded and followed by colic, 2.
• Diarrhœa, followed by urging to stool in the rectum, 1.
• Slight diarrhœa (fourth day), 71b. [510.]
• Violent diarrhœa, 17, 32.
• Almost incurable diarrhœa, 19

[See note to S. 278.]

• Ash-colored diarrhœa (as in jaundice), 47.*
• Ash colored, pasty diarrhœa, as in jaundice, follows four attacks of vomiting, with faintness thereafter, 36.
• Painful diarrhœa for three or four days, 51

[Not found. -Hughes.]

• Bowels rather relaxed (fourteenth and fifteenth days), 63b.
• Several stools during the day, 28.
• Several fluid stools (second day), 65.
• Several bilious stools (third day), 65.
• Two and three stools a day for several days, 7. [520.]
• Bowels moved naturally in the morning and again at nine in the evening (second day), 66.
• Thin stool two or three times a day, the next morning constipation (after twenty-four hours), 12.
• Two thin discharges from the bowels at one and eleven P.M., 53.
• Abundant stools (very soon), 82.
• Copious stools, 83.
• Intestinal evacuations were copious, and seemed to contain a good deal of bilious matter (sixteenth day), 65b.
• Gentle intestinal evacuations, which were bilious and mucous (nineteenth day), 65b.
• Involuntary stool, 1.
• Soft, liquid profuse stool (after seventy-two hours), 3.
• Thin stool, 5. [530.]
• Yellowish-white stool, without symptoms, follows retention for forty-eight hours, 3.
• Slight fecal evacuation (second day), 65.
• One scanty green evacuation from bowels (third day), 76.
• Many thread worms with the stool in the evening, 12.
• Constipation.
• Constipation (for several days), 75, 81.*
• Constipation nearly the whole time, 10.
• Bowels confined, 85, 92.
• Stool somewhat retained during all the provings, very unusual, since the stools have always been free and healthy, 64.
• Fæces scanty, 74.
• Very hard, difficulty, though rather copious stool at 11 P.M. (first day), 64h.

URINARY ORGANS

• Kidneys and Bladder. [540.]
• Function of kidneys completely suspended, 85, 92.
• Contractive pain in the bladder while urinating, with difficult discharge of urine, 8.
• Dragging sensation in the bladder, as though it were distended; not relieved by frequent micturition (second day), 62.
• Urethra.
• Pressing burning in the middle of the urethra, as if it were too narrow, while urinating; it, however, disappears even while urinating, 1.
• Urging to urinate, 5.
• Urging to urinate, even to inflammation of the neck of the bladder, 37.
• Urging to urinate, with much urine of a healthy color (after eight, nine and ten hours), 2.
• Urging to urinate, with copious micturition, lasting from 10 A.M. (two hours after second dose), till 3 P.M. of the next day, 62.
• Frequent urging to urinate, 61 , [Part of S. 460.]*
• Frequent urging to urinate, with only a dribbling discharge of reddish urine, with burning in the urethra and glans penis, 9. [550.]
• Constant urging to urinate at night , and, on rising, in consequence, dizziness and vertigo, 9.*
• Incessant urging to urinate, and passage of only a few drops at time ; urine dark brown, hot, burning, while passing (ninth day), 6.*
• Incessant desire to urinate, without passing much at a time, though the aggregate amount was large (first and second days), 57.
• The fits are often preceded by frequent ineffectual desire to urinate, 74.
• Awakened about 3 o'clock at night by the necessity to pass urine, which, however, was passed in only a very small quantity (first night), 64e.
• Violent, fruitless efforts to urinate, 35.
• Micturition.
• Urine increased, 74.
• Quantity of urine increased (eight and ninth days), 65b.
• Quantity of urine increased (fifth day), .

[A very unusual alternate action of Digitalis, and only from very large doses. Difficulty of micturition is usually the primary action of this drug, wherefore it is frequently used homœopathically and very beneficially for enlargements accompanied by similar difficult micturition and by other symptoms, which are found to be like the pure primary action of Digitalis. The copious and often involuntary micturition or profuse secretion of urine that follows its use, is only the reaction of the organism from the supposed primary action. -Hahnemann.]

• Urine was more abundant and deeper in color (sixteenth day), 65b.
• Urine much more abundant (fourteenth and fifteenth days), 63b.
• Quantity of urine excreted much greater than the quantity of fluid drank (first day), very abundant (second day), 65. [570.]
• Urine was secreted in such large quantities, that she passed more in two hours than usually in twenty-four; therewith the thirst was not increased (two hours after dose, fourth day), 62.
• Urine copious; voiced at least every two hours during the afternoon (third day), 60.
• Urine copious; passed six times between 3 and 10 P.M. (usually but twice in the same period); urine showed no especial change, but after several hours deposited a thin brownish sediment (fourth day), 58.
• Urine copious, and depositing a mucous sediment (nineteenth and twentieth days), 65b.
• Urine more copious than usual during the afternoon (second day), 60.
• Urine profuse; evacuated every hour during the afternoon (first day), 55.
• Urine more profuse than usual, lasting till noon of the third day (second day), 61.
• Urine more profuse than usual; after 10 A.M., constant urging renewed immediately after micturition; this urging, however, caused no real pain, and the urine, which was darker colored than usual, caused no burning during micturition (fifth day), 61.
• After seven hours (after 3 P.M.), it seemed as though the kidneys became very active, and secreted urine rapidly, followed by urging to urinate, and copious discharge of normal urine (third day), 58.
• Frequent urinating, and more urine, also at night, 95. [580.]
• Frequent passage of watery urine, 1.
• She is obliged to rise every night to urinate, 1.*
• Inability to retain the urine, 51.
• Involuntary micturition, 1.
• Involuntary discharge of urine and fæces (after seven days), 84.
• Quantity of urine lessened; it was clear and of a pale color (twenty-second day), 65b.
• Urine less abundant, and of a red color (third day), 65.
• Urine during the first day decidedly diminished (too much so to be accounted for by the warmer weather), 860 c.c., gr. 1025 (aggregate of four evacuations), (first day); passed in unusually small quantity, and of very high sp. gr. (1033), (second evening); total amount during the day only 1050 c.c., though I drank 180 c.c. of beer and 210 c.c. of coffee; in the afternoon the reaction was neutral; average sp. gr. 1.026.5 (second day), .

[Is it not remarkable that Digitalis, when taken in a poisonous dose, suppressed the very function which it excites to increased activity when administered as a medicine?]

• Passage of dark urine, amounting from noon till 10 P.M. to 1 1/2 lbs., 53.
• Quantity of urine, 1873.6 centimetres; sp. gr., 1014.32; total solids, 63.74 grams.; inorganic solids, 30.15 grams.; organic solids, 33.49 grams (second day), 72. [600.]
• Quantity of urine 1624.9 c.c.; sp. gr., 1020.04; total amount of solid matter, 67.29 grams., of which 33.19 were inorganic, and 34.10 organic (third day), 72.
• Micturition difficult, as though there were almost no urine in the bladder, and yet there was great urgency to urinate; after micturition, pressure in the bladder and burning in the urethra for half an hour (third day), 64g.*
• Urine.
• Urine of pale straw color and feeble acid reaction; quantity, 1950 c.c. (previous average, 1475.5 c.c.); sp. gr., 1013.25 (previous average, 1024.30 c.c.); total solids, 69.98 grams., of which 31.27 were inorganic, and 38.71 organic matter (previous average, 75.31 grams., of which 37.17 grams. inorganic, and 45.14 organic constituents), (first day), 72.
• Urine very red and burning (fourth day), 71b.
• Urine dark, without urging to urinate; it becomes very red, and deposits a sediment (after fourteen hours), 2.
• He observed while taking the medicine that the urine was of a brownish color, and a heavy, disagreeable smell, 66.
• Acid urine, 51

[Not found. -Hughes.]

• Urine thick, with dense white sediment (fifth day), 76.
• Urine, 1125 c.c., acid; sp. gr., 1025 (first day). 1040 c.c., acid; sp. gr., 1025 (second day), 1040 c.c., acid; sp. gr., 1025, very soon becoming turbid (third day). 940 c.c., acid, once in the afternoon neutral; sp. gr., 1024.6 (fourth day). 900 c.c.; sp. gr., 1025.8; in the afternoon neutral, at other times acid; in the morning and afternoon after dinner it became very turbid after a few hours, and deposited a thick white sediment (fifth day), 64c.
• Urine, 1150 c.c., acid; sp. gr., 1053 (first day). 870 c.c.; sp. gr., 1023 (second day). 1145 c.c.; sp. gr., 1017.2 (third day). 975 c. c; sp. gr., 1025 (fourth day). 1100 c.c.; sp. gr., 1018.3 (fifth day). 1200 c.c. (once neutral); sp. gr.; 1024.3 (in the forenoon 120 c.c. of weiss beer were taken), (sixth day). 825 c.c.; sp. gr., 1026.9; in the afternoon becoming soon very turbid (seventh day). 1110 c.c.; sp. gr. 1026 (eighth day). 1105 c.c.; sp. gr., 1025.4 (ninth day), 64d. [610.]
• Urine, 1430 c. c, acid; sp. gr. (evening), 1030 (second day). 950 c.c.; sp. gr., 1022, neutral in the morning and afternoon (third day), 64e.
• Urine 1460 c.c.; sp. gr., 1018.5 (first day). 1360 c.c.; sp. gr., 1024 (second day). Neutral in the evening, not after dinner, both days, 64f.

SEXUAL ORGANS

• Male.
• Irritability of the genital organs after different doses, 59.
• Constant irritability of the genital organs, almost painful erections, especially disturbing sleep (fourth day), 61.
• Continued erections in the morning on rising, which were remarkably unpleasant, and almost painful on account of the urinary troubles (third day), 64g.
• Very noticeable and persistent erections in the morning, not only in bed, but also after rising (fourth and subsequent days), 61e.
• Awakened at night by almost chordee-like erections, and at same time, urging to urinate, with, however, very scanty urine, much out of proportion to the urging (third night), 61g.
• When Digitalis (or Digitaline) is administered for some time to a man in full possession of sexual powers, these become gradually reduced, the propensities disappear, formation of liquor seminis diminishes, and may at last cease altogether, 73.
• Genitals become so weak and flaccid, that they are hardly felt to exist; heat, tension, congestion, and erection of the parts, pleasurable feelings, and sexual desire, are no longer experienced, 88.
• Great irritation of the genitals, 58 ; (part of S. 59), 58. [620.]
• Itching irritation in the glans penis; (part of S. 460), 61.
• Frequent sensation at night as though an emission would occur without one; in the morning a glutinous moisture at the orifice of the urethra, 1.
• Pain, as from a bruise in the right testicle, 1.
• Very excited lascivious fancies, with voluptuous images day and night, and frequent erections, 10.
• Excited sexual desire, with frequent erections during the day, 6.
• Emission, without dreams and without waking, during the night (an extraordinary symptoms, which I had not experienced for more than a year), (second night), 64b.
• Emissions almost every fourth night, always with voluptuous dreams, 6.
• Three emissions within four nights, followed by great exhaustion on the following day, but with violent erections every morning on and after rising (after ten days), 64d.
• Emissions, followed by pain in the penis, 10.
• Copious emission at night (first night), .* [630.]

RESPIRATORY ORGANS

• Larynx.
• In the morning, mucus in the larynx, easily loosened, but by hawking; it usually comes up into the throat, so that he is obliged to swallow it, 4.
• Tenacious mucus in the larynx, loosened by a hacking cough, 6.
• On every inspiration he feels as though he were electrized, 46.
• Irritation to cough, as far up as the arch of the palate, 1.
• Hoarseness in the morning, 1.
• Hoarseness in the morning on waking, 10.
• Great hoarseness, so that he is unable to speak, in the morning after a night-sweat, 1. [640.]
• Frequent painless hoarseness, 6.*
• Cough and Expectoration.
• Cough and catarrh, so that he could scarcely speak, 1.
• Cough with sweat, at midnight, 1.
• Slight cough, which a appeared sympathetic with the affection of the stomach (eighteenth day), 62b.
• After eating, the cough is so violent that he vomits the food, 1.
• Dull cough, as from tickling in the trachea, without expectoration, 12.
• Dry cough, with dyspnœa, in the morning after rising, 5.
• Dry cough, with pressive tensive pain in the arm and shoulder, 12.
• Cough, caused by itching irritation in the larynx, short and dry, 6.
• Dry spasmodic cough, after much talking, 1. [650.]
• Cough and expectoration, with a peculiar weak sensation in the chest, especially on sitting a long time (fourth day), 64e.
• Expectoration of mucus in the morning by involuntary hawking, 7.
• Expectoration of grayish mucus, of a sweetish, offensive taste (second day), 64e.
• [Expectoration from the chest colored by blood], 42

[A standing symptom with the patient. -Hughes.]

• *Bloody cough, 1.
• Respiration.
• Respiration more rapid (seventh day), 78.
• *Respiration irregular, and performed by frequent deep sighs (second day), 76.
• Short, gasping respiration; he is not able to hold it, and is soon obliged to gasp anew, 3.
• Sighing respiration for six days, 78.
• Respiration 16, difficult (fourth day), 81. [660.]
• Respiration 26 in a minute, but without any difficulty (second day), 65.
• Respiratory murmur feeble (second day), 76.*
• Respiration difficult, slow, and deep, 11.*
• When sitting, as well as when walking, worse towards evening and in the evening; *there was a constant desire to take a very deep breath, but on attempting to do so, it seemed as though the chest could be only half filled, or as though some impediment existed deep in the chest; there was associated with this a dry cough, especially on deep inspiration , which only seldom expectorated a somewhat hard, lumpy mucus; in the morning, however, the expectoration was freer and more copious than in the afternoon and evening; everything seemed too tight about the body; I was obliged to open my vest and waistband, because their pressure was extremely irksome; this, however, did not relieve the shortness of breath (fourth day). On the next day, the shortness of breath appeared in a slight degree immediately on rising (the previous evening it had soon disappeared in bed), but was now accompanied by a painful feeling of weariness and general affection of the chest, and a frequent dry cough; in the afternoon the difficulty of respiration increased, and in the evening it was worse than yesterday, especially while writing (fifth day). On the next day this continued, a little less in the morning, but even more violent in the afternoon and evening than before, even accompanied with some palpitation (sixth day). The next day, the shortness of breath was noticed immediately after rising, though there was no cough and very little expectoration; in the afternoon and evening it was noticed a little while walking (seventh day); in the evening walk after this, the shortness of breath continued to return in shorter and slighter attacks, until it gradually disappeared, 64h.
• Extremely annoying shortness of breath during the whole day; this had been noticed during the preceding days, but in so slight a degree that I paid little attention to it; it was, however to day very severe (sixth day), .

CHEST

• Œdema of the lungs, 74.
• Weary sensations across the chest to the left side (two hours and a half after first dose, second day), 66.
• Cough is difficult on account of pain in the chest, 47.
• Great heat of the chest externally, as if he stood uncovered by a warm stove, soon followed by coolness over the chest, 5. [670.]
• Tension in the chest and pressure in the pit of the stomach, which frequently obliged him to take a deep breath, 11.
• Suffocative, painful constriction of the chest, as if the internal parts were grown together , especially in the morning on waking; he is obliged to quickly sit upright, 1.*
• Pressive drawing in the chest on coughing, 3.
• Pressure and boring in the pectoral muscles above on the left side, 95.
• Pain in the chest; a pressure on the lower portion of the chest, while sitting bent over, with shortness of breath, 3.
• Dull, disagreeable pressure in the chest and epigastrium relieved by beating on the chest, lasting three hours, towards evening (eight day), 66.
• Feeling of rawness in the chest, with stitches, 1.
• Front.
• Contractive pain in the sternum, aggravated by bending forward the head and upper portion of the body, 2.
• Drawing pain in the middle of the sternum while walking, 3.
• On violent motion of the arm, he is immediately attacked by cutting pressure in the opposite side of the chest, externally, in front, in the region of the third rib, 3. [680.]
• In the evening, a bruised feeling over the sternum and epigastrium, so very distressing as to prevent any mental employment (fifteenth day), 66.
• Sides.
• Tension in the left side of the chest, on becoming erect, as if the parts were contracted, 3.
• Violent drawing-pressive pain in the lower portion of the right side of the chest, in the evening, preventing sleep (sixth day), 64h.
• Dull pinching stitches under the ribs beneath the right axilla, 6.
• Sharp stitches in the chest, on the right side, above the pit of the stomach, .

HEART AND PULSE

• Præcordium. [690.]
• Uneasiness in the heart all day (sixth day), 70.
• Uneasiness at the heart in the afternoon (fifth day), 66.
• Throughout the day frequent uneasiness amounting sometimes to pain, in the region of the heart (fourteenth day), 66.
• Slight uneasiness in the region of the heart (sixth day), 66.
• Continued to suffer much from uneasiness in the heart and disorder of the stomach (nineteenth day), 66.
• Dull uneasiness in various parts of the region of the heart, with a sensation of weakness in the forearm, all the evening (second day), 66.*
• Feeling of slight confusion of the heart, especially on moving, with painful sensation of weakness in the wrists and forearms (half hour after second dose, second day), 66.
• Dull, disagreeable sensation in the region of the heart (after second dose, second day), 66.
• *A sudden sensation as though the heart stood still, with great anxiety , attack lasting about half a minute, not returning; pulse and heart not affected, at 9 P.M. (after 10 drops in the morning), 64.
• Sudden sensation as though the heart stood still, with great anxiety and necessity for holding the breath , after dinner (sixth day), 64d.* [700.]
• Peculiar sensation in the chest, as of the heart standing still ; single, violent, slow heart-beats, with sudden violent heat in the occiput, and transient unconsciousness, the whole lasting only a moment, 95.*
• Pain in the heart, with which I had been troubled, was more severe than ever this morning, and from the ensiform cartilage upward my breast was sore to touch (fifth day), 70.
• Slight pain, apparently in the heart, and in half an hour the pulse was softer, smaller, but more rapid than natural (second day), 63.
• Felt uncommonly well, except that I thought I sometimes felt shifting pains in the heart, for the first three days, 70.
• Oppression of the heart (second day), 71b.
• Oppressive sensation in the heart, and need to inspire deeper, 95.
• Attack of the so-called heart-worm ("herzwurm"), with intermitting pulse and congestion of the head, especially in the occiput, somewhat to the left side, and inclination to vomit (after twelve hours), .

[Subsequent to S. 763. -Hughes.]

• Pulse 68 before taking; 68 (after five minutes); 72 (after ten minutes); 74 (after fifteen and twenty minutes); 70 (after twenty-five minutes); 68 (after thirty minutes); after which no farther change was observed, although attention was paid to it for some time longer. It was not only excited in frequency by the simulating power of the pill, but also considerably in force, 93.
• Pulse 80 after gentle exercise (fifth day); 80 when at rest, but rose to 85 or 90 when I had walked for a few minutes (eighth day); 85 whether lying or sitting, 90 to 95 when I had walked a little (thirteenth day); 100 full and strong (fourteenth day); 85 while I remained quiet, although it rose to 100 after gentle exercise (sixteenth day); 80 (seventeenth day); 80 full and strong (eighteenth day); 85, rather weak and irregular, especially after having taken exercise (nineteenth day); 70, softer and fuller (twenty-first day); softer and fuller, 60 but rose to 75 upon slight exercise (twenty-second day); 50 to 65, when I remained quiet, but rose to nearly its natural number when I used much exertion; still it was full, although soft and easily depressed (twenty-third day); it never fell below the degree just indicated, and nearly a week after it had resumed its natural rhythm, 63b.
• Pulse before taking, 56 while sitting, at 10 A.M., ten minutes after dose no change; after twenty-eight minutes, 55 or 56; but on standing, it immediately rose to 72; at 6 P.M. 54 to 56 sitting, 68 standing; at 11 P.M. 69 sitting, 88 standing (first day); at 10 A.M. 61 sitting, 69 standing (second day); at 11 P.M. 82 sitting, 90 standing, small, weak, and somewhat irregular, the beat of the heart is stronger and more distinctly felt than usual (fourth day). In the morning, 57 sitting; at 7 P.M. 74 sitting, 86 the first minute, 94 the second, on standing, without perceptible irregularity it remains for a few minutes at this rate and then becomes slower (fifth day); at 9 A.M. 52 sitting, 60 standing; at 11 A.M. 50 sitting, very full, strong, and regular (sixth day); at 9 A.M. 59 sitting, 72 standing (seventh day), 64h.
• Pulse in the morning before exercise was uniformly 60, feeble; at night after sitting for about two hours 56, feeble, before taking. 70 in the morning; 66 in the evening (first three days). Pulse before breakfast 76, strong; in the evening 70 (fifth and sixth days). 80 in the morning, 90 in the evening (seventh and eight days), continuing nearly 70 the same for three days, 78, pretty full (tenth day). returned to its natural standard (seventeenth day), 76.
• Pulse averaged in the forenoon 68, abound in the evening 75, before taking; 68 after sitting quietly for an hour; 68 sitting quietly (after half an hour), (first day); 66 (twenty minutes after first dose); 76, of natural strength, after walking four or five times up and down the room; 83 (two hours and a half after first dose), 75 (five hours and a half after first dose), 80 (half an hour after second dose), 76, counted several times in gave the first half minutes 36, the second 40, and 3 beats failed to be felt (one hour after second dose), 80 (nine hours after second dose), 78, weak, (ten hours after second dose), (second day); 62, small and weak in the morning, 72 in the evening (third day); 80, full and regular before taking; 90, weak, three or four pulsations in a minute hardly felt (after three-quarters of an hour); 82, nearly natural in strength, not steadily so (after twelve hours), (fourth day); 76 before taking, 84 (after half an hour); 76, rather weak in the evening (fifth day); 72 before taking, 88 irregular (after one hour), 84 less irregular (after two hours), 72 regular (after four and a half), (seventh day); 72 regular (eight day); 73 in the morning (ninth day); 78 at 6.30 P.M. (tenth day); 73, natural, before taking, 80 (one hour and a half after first dose), 76 (three hours after first dose), 62 (five hours after first dose), (fourteenth day); 72 in the morning (fifteenth day); 75, a little irregular after walking before taking, 84 (one hour after first dose), 86, slightly irregular (one hour and a half after first dose), 100, irregular, but full in the evening (after second dose), (sixteenth day); natural, but very readily excited (nineteenth day), .

[Original revised by Hughes.]

• *Pulse irregular, 74.
• Irregular pulse ; Unequal distension of the arteries, 41.
• *Irregular, small pulse, 23, 49.
• *Pulse small, slow, irregular, 74, 82.
• Small irregular pulse, continuing six days, 78.
• Pulse slow and irregular, 83.*
• Slow irregular pulse from 48 to 56, 16

[Original revised by Hughes.]

• Pulse late in the evening 58, irregular; after a time slower and fuller, then again more rapid and smaller (second day); 61 in the evening (third day), 64c.
• Pulse 52, quite strong, irregular, and strinkingly intermittent, 81.
• Pulse full and strong (fifth day).
• Pulse 50 (ninth and twelfth day); strong, full, 46 pulsations; their shock was rapid and separated by considerable intervals, when at rest, but on very slight exercise rose to 70, and even 80, became irregular and less full (fifteenth day), 65c. [780.]
• Pulse slow, 50; it quite irregular; always a full hard beat after every three or four soft ones (first day); 75 (third day), 3.
• *Pulse decidedly irregular, three to four rapid small beats were followed by several slow, strong, and full beats; no regularity in this disturbance could be discovered (seventh day), 64d.
• Pulse extremely low, three or four feeble pulsations being succeeded by a complete intermission occupying several seconds; the whole number of beats not exceeding 38 or 40 in the minute; each stroke, though very weak, was given with a peculiar explosive shock; this condition of pulse lasted for several days, 85.
• Pulse slow, thready, and intermittent, 74.*
• Pulse fell from 60-70 to 54, and frequently intermitted ; with every intermission an oppression as if the heart were slowly grasped with the hand (after two hours), 71b.
• Slight intermission in pulse, 87.
• Small, slow pulse, frequently making shorter or longer pauses, 2.
• Pulse suddenly quickened for a few beats, then slow again; or it loses a whole beat, 34

[Original revised by Hughes.]

• The pulse changes rapidly from 65 to 75, and 80 (also on times when no medicine is taken), 95.
• Pulse varies from one beat slower to two beats faster (during half an hour after taking 30 drops of tinct), 75. [790.]
• Pulse undulating; the different beats are not all distinct and clearly defined as usual, but shading off at the beginning and end, at noon (second day), 64c.
• Pulse regular, and moderately strong (second to seventh day while taking), 73.
• Pulse regular and moderately strong throughout the proving; including the period of "intoxication," the effect on the pulse lasted about a month, 75.
• Pulse hard and strong (second day), 76.
• Pulse full, 74.
• Irritable pulse, 30.
• Pulse small and soft (two hours after two grains), 57.
• Pulse smaller than usual, of the usual rapidity (first day), 54.
• Pulse smaller than usual, but not slower (first day), 36.
• *Beating of the pulse and heart seemed rather smaller and less energetic than usual (fourth day), 58. [800.]
• Almost pulseless (after twelve hours), 76.

NECK AND BACK

• Neck.
• Stiffness and pain in the muscles on the right side of the nape of the neck, especially when bending the head (lasts till going to sleep, and does not disappear finally till the forenoon of the following day), 95.
• Painful stiffness and tension of the neck and throat, especially on motion, 12.
• Pressive drawing in the nape of the neck, at the occiput, at the point of insertion of the cervical muscles, on bending the head backward, 3.
• Painful pressure in the cervical muscles, as if pressed by a band, 1.
• Cutting pain, with a numb sensation in the nape of the neck, obliging him to draw the head backward, which seems to be hindered by a soft dead substance compressed between the joints, 3.
• Sticking in the cervical muscles, on moving the neck, 2.
• Tearing and sharp sticking in the nape of the neck, on motion, 6.
• Sore pain in the articulation of the first dorsal and last cervical vertebræ, on bending the neck forward, not when touched, 3.
• Bruised pain in the nape of the neck, between the shoulders and extending forward over the anterior part of the chest, where the flesh was painful when pressed, especially over the sternum. This was attended with dull frontal headache, bruised pain in the epigastrium, with feeling of distension of the stomach (in the early part of the evening of the fourth day, and felt more on the fifth day), 66.
• Back. [810.]
• Stiffness of the back and on the sides of the neck, with a thrust like pressive pain, 5.
• Drawings in the back, upper and lower limbs, and the fingers, as after taking cold, 11.
• Tearing and sharp sticking in the back, on moving, 6.
• Dorsal.
• Sensation as of a thrust in the first dorsal vertebra, 5.
• Dull stitches between the scalp ilea, 1.
• Tearing beneath the right scapula, 4.
• Lumbar.
• Pain in the small of the back, on stooping, 1.
• Slow drawings above the nates, 3.
• Pressure on both sides of the spine in the lumbar region, after the stool, .

EXTREMITIES IN GENERAL

• Objective.
• Tense painful swelling, first of the legs, then also of the hands and fingers, only slowly disappearing after several months; pulse not at all slower, and the discharge of urine not increased, 31.
• Great weakness of the arms and legs, 3.
• Subjective.
• Heaviness and sluggishness of the limbs, 38.
• Heaviness and helplessness of the limbs, 10.
• Drawing in the elbows and knees, 95.
• Pains in all the joints, as if sprained, after the midday nap, 1. [830.]
• Piercing pains in the joints, 1.
• Each complained that his fingers and the extremities of his toes were affected alike, a burning sensation, as if pierced by needles, 79.

SUPERIOR EXTREMITIES

• Paralytic weakness of the left arm, he is scarcely able to raise it, and cannot clench the fingers without pain, 5.
• A sore-like burning of the right arm, 1.
• Painful tensive pressure in the muscles of the arm and shoulder, on moving the arm, 12.
• Shoulder.
• (Much muscular rheumatism in the right shoulder, allowing but little sleep in the night, only disappearing after seven days), 64b.
• At night, violent pain in the left shoulder and elbow-joints, together with semiconscious sleep, lying upon the back with the left arm over the head, 11.
• Pressure in the right shoulder, several times, and in the left knee, 95.
• Arm.
• Heaviness of the left arm, even noticed during rest, 1.
• Burning sticking in the left upper arm, 5. [840.]
• Tearing stitches in the right upper arm, when walking, 7.
• Needle-like stitches in the lower part of the upper arm, continuing even on moving it, 11.
• Painful itching throbbing in the flesh of the upper arm, 1.
• Elbow.
• Pressing in the right elbow, 95.
• Painful sensation in the elbow-joint, as if the nerve were pressed upon, or as though the arm would go to sleep, also noticed on touching the part, 11.
• Forearm.
• A paralytic pain in the middle of the ulna, on stretching out the arm, or when it lies outstretched, 3.
• Pinching and sharp sticking pinching on the back of the ulna above the wrist, 4.
• Severe stitches in the muscles of the right forearm.
• Violent tearing in the right forearm, during rest and motion, 7.
• Wrist.
• Violent boring in the right wrist towards the thumb (lasting), 95. [850.]
• Paralytic tearing in the bones of the wrist, 4.
• Hand.
• Swelling of the right hand and fingers, lasting three hours, at night, .

INFERIOR EXTREMITIES

• Objective.
• Infiltration of lower extremities (after four days), 84.*
• Staggering, 74 ; (soon), 85, 92.
• Subjective.
• Great stiffness of the joints of the lower extremities, after sitting (in a wagon); relieved by walking, 1.
• Weakness of the legs; is constantly obliged to stretch them out, 5.
• Weakness and weariness of the legs, with trembling, 11.
• Loss of power and paralytic weakness of the legs, 5.
• I experienced in my a feeling of great fatigue (third day), 65.
• Painful drawing in the right leg, especially in the thigh, when sitting; then in the right knee and right ankle, 95.
• Thigh. [870.]
• Spasmodic movements in the muscles of thighs (after ten hours), 76.
• Nates fall asleep, in the evening while sitting, and feel dead, 3.
• In the bend of the thighs a pressive tension in the tendons of the lumbar muscles, which become prominent on motion, though almost only while walking; on pressure upon them there is pain, as from the pressure of a hard body under the skin, 3.
• A drawing cramp in the forepart of the hard body under the skin, 3.
• A drawing cramp in the forepart of the bend of the right thigh, aggravated after motion of the lumbar muscles, when it becomes a bubbling, and continues even while sitting, 3.
• Aching in the thighs and legs, on beginning to move after lying down; they feel bruised, 1.
• Drawing in the inner side of the thigh, while sitting, 3.
• Cramplike drawing in the muscles of the thigh above the popliteus, while sitting, disappearing after walking awhile, 3.
• Pressive drawing in the anterior muscles of the thigh, 3.
• A pain, rather pressive than drawing, on the anterior portion of the thigh, gradually increased and again diminished, 5.
• Cutting in the thigh, on laying one leg over the other, disappearing on separating the legs, . [880.]

GENERAL SYMPTOMS

• Objective.
• Tense white swelling of the whole body, with great painfulness to every touch, after several weeks subsiding, becoming soft, and changing to anasarca, 31.
• Bending forward of the body is attended with violent tearing pain in the abdomen, for six days, 78.
• Wasting of the body in proportion to the recuperation of the mind, 40.
• Fatal apoplexy, 48

[The reporter writes he was suddenly and unexpectedly carried off with all the dreadful distress and jactitation which an overdose of Digitalis sometimes produces. His death was pretty generally ascribed to apoplexy, and was, indeed, truly apoplectic. -Hughes.]

• Universal and partial trembling, for six days, 78.
• Convulsions, 51, 82 , etc.
• Convulsions and great disquietude, 74.
• Convulsions of the most violent kind, 28.
• Epileptic attacks, 45. [910.]
• Stiffening of the body, for six days, 78.
• The trunk and limbs especially the thighs, are painfully stiff (tenth day), 6.
• Relaxation of all the muscles, with sensation as though he had not slept enough, 3.
• Sinking of vitality, 1.
• Lassitude, 81.*
• General lassitude, exhaustion, and weariness of body and mind (fourth and fifth days), 61.
• The listless state of the body and depression of the mind had increased; the latter was a kind of stupidity (eighteenth day), 65b.
• Extremely listless and weak (nineteenth and twentieth days), 65b.
• Weakness sinking of the strength, 51.*
• *General weakness, 39, 49. [920.]
• General weakness, as if all portions of the body were weary (after two hours), 5.
• Frequent weakness; she was obliged to lie in bed because sitting up fatigued her, 42.
• *Great weakness, 41, 43.
• Extreme weakness, 23.*
• Sudden extreme weakness, as if he would lose his consciouness, with general heat and sweat, without thirst, after dinner, 1.
• Weakness, as if to death, 34.
• Weak and tired (seventeenth day), 65b.
• My strength was extremely weakened (fourth day), 65.
• Sudden sinking of strength, with general sweat, and after some hours cough, 1.
• Could not for several days bear the upright position, , . [930.]

SKIN

• Objective.
• General paleness of the skin, 23.
• (Jaundice), 51

[This occurred in several of Withering's patients, but always in a natural sequence of their maladies, and never was traceable to Digitalis. -Hughes.]

• Desquamation of the skin of the whole body, 34.
• Eruptions, Dry.
• Eruption on the upper lip, 1.
• Itching eruption on the cheeks and chin, which desquamates and leaves behind red spots, 10. [970.]
• Papular eruption on the back, 1.
• Rash on the back of the hands, without sensation, 1.
• A large pimple, with biting pain, beneath the left nostril, 1.
• A red pimple, with biting pain, beneath the left nostril, 1.
• A red pimple, with burning-biting pain, aggravated by touch, on the middle of the forehead, 5.
• Eruptions, Moist.
• A cluster of vesicles developed on the chin in the morning, such as I had formerly had only on the lips (fourth day), 64d.
• Eruptions, Pustular.
• Black comedones in the skin of the face, which suppurate and ulcerate, 10.
• A small, very painful furuncle on the nape of the neck (seventh day), 64d.
• Subjective.
• Corrosive itching, that becomes constantly worse when he does not scratch, and at last increases to an intolerable burning, needle like stitching, which at one time disappears, at another returns worse than ever, 4.
• Biting and itching on the cheek and chin, worse at night, 1.
• Tickling of the affected parts of the body, 44. [980.]
• Itching of the back of the hand, mostly at night, 1.
• Itching on the back of the right foot, mostly at night, 3.
• Voluptuous itching in the axillæ, 3.
• Corrosive itching in various parts of the body, returning soon after scratching, 4.
• Corrosive itching in the left region of the loins, obliging him to scratch, 4.
• Corrosive itching in the upper and anterior portion of the thigh, 4.
• Corrosive itching on the leg, above the external malleolus, 4.

SLEEP AND DREAMS

• Sleepiness.
• Frequent yawning and stretching, with chilliness, 72.
• Drowsy and incapable of study till evening (eighth day), 70.
• Sleepiness early in the evening, with indolence and dullness of mind for several days, 10. [990.]
• Frequent sleepiness, 20.
• Great sleepiness after eating, with frequent yawning after dinner, for several days, 1.
• Frequent great sleepiness, 34.
• Sleep, 28.
• Deep sleep, 34

[Curative effect. -Hughes.]

• Fell into a deep sleep, 83.
• Deep sleep from noon till midnight, 28.
• A long, sound slumber (first cupful), (immediately), 85.
• Lethargic sleep, lasting several hours, 82.
• Coma, 28. [1000.]
• Coma, followed by death (after twenty-two hours), 82.
• Coma, interrupted by violent convulsive attacks of vomiting, 23, 49.
• Sleeplessness.
• Difficult falling asleep (sixth and seventh days), 6.
• It was with difficulty that I could sleep, although I was at times in a state of stupor (nineteenth and twentieth days), 65b.
• Sleep disturbed and uneasy (fifth day), 61.
• Uneasy sleep; he lies only upon the back, 8.
• Sleep uneasy and unrefreshing (second day), 62.*
• Uneasy sleep at night on account of constant urging to urinate, 9.
• Uneasy sleep, with tossing about the bed and voluptuous dreams, 5.
• Very uneasy sleep, with frequent waking, and burning heat of the face, subjective as well as objective as well as objective (first night), 64c. [1010.]
• Frequent waking, as from anxiety , and as if it were time to rise, 1.*
• Frequent waking at night in fright , by dreams of falling from a height or into water, 7.
• But little sleep, disturbed by dreams (sixteenth night), 65b.
• Slept but little during the night, and my mind had somewhat of that restless activity which I have experienced after taking too much wine, but particularly after taking Tinct. Opii (sixth night). Very drowsy when I went to bed, but did not sleep soundly (seventh night), 70.
• Restless sleep, with tossing about and waking with semi-consciousness, 11.
• Tossing about at night, with frequent waking, always lying upon the back, with emissions, 10.
• At night, only slumbering instead of falling asleep; complete consciousness without being able to sleep, .

FEVER

• Chilliness. [1030.]
• Skin cold, 81.*
• Skin very cold, with palpitation, 74.
• Coldness of the body, with clammy sweat, 51

[Not found. -Hughes.]

• *Great coldness of skin . (soon), 77.
• Cold pale, covered with a copious perspiration, 74.
• Excessive sensitiveness to the cold, 10.
• Chilliness, 12 ; (after eight hours), 80.
• Chilliness before the stool, 1.
• Chilliness over the whole body, with heat and redness of the face, 13.
• Constant chilliness, mostly in the back, 11. [1040.]
• Internal chilliness of the whole body, white externally perceptible warmth, which is increased, 4.
• Internal chilliness during the day; he was unable to get warm on walking in the open air, 1.
• Coldness and chilliness, internally and externally, of the whole body, 4.
• Coldness of the whole body, perceptible externally, with warm face, 2.
• Internal coldness of the whole body, 4.*
• Felt cold all over (after three hours), 81.
• Very cold, 85.
• After the last vomiting, a chill, which was followed by considerable heat and dryness of the surface of the body, to which succeeded slight pain in the inferior extremities, especially in the calves and knees (second day), 65.
• I shivered at a temperature of 15° (Reaum), (twenty-second day), 65b.
• Shivering three or four times in the afternoon, followed by sweat at night, even of the head and in the hair, 1. [1050.]
• Frequent shiverings (fourth day), 63.
• Slight shiverings, which were followed by increase of the heat of the skin (sixteenth day), 65b.
• Frequent shudderings, 93.
• Slight rigor, followed by increased heat (after ten hours), 76.
• Chilliness in the back, 2.
• Chilliness in the back, cold hands, lasting several minutes, 95.
• *Cold extremities, 74.
• *Coldness of the limbs, , .

[Not found. -Hughes.]

• [Febrile paroxysm, first shivering then heat, then profuse perspiration], 39

[Accompanying purulent expectoration. -Hughes.]

• The disease did not differ essentially from what is usually called typhoid fever, with particular affection of the gastric viscera, 63.
• Heat in the head and face, 95.
• In the beginning, heat in the back, then creeping coldness, with cold hands, shuddering through the back, lasting several minutes, 95.
• Burning heat in the hands, 95.
• Burning of the head, face, and ears, with redness of the cheeks and slight chilliness in the back; the left eye is also much smaller than the other (after eating in the room), 12.
• Sweat.
• Skin inclined to be moist (eight and ninth days); moisture increased (fourteenth and fifteenth days), 65b.
• Nightsweat during sleep, 1. [1080.]
• General slight sweat in the morning on waking, 7.
• Covered with a copious perspiration, 85.*
• Cold sweat, continuing six days, 78.
• Body covered with cold sweat (seventh day), 78.
• Warm perspiration in the palms of the hands, 5.

CONDITIONS

• Aggravation.
• ( Morning ), On stooping, immediately after rising, headache; on waking, headache; on waking, all objects seem covered with snow; coryza; vomiting ; pain about umbilicus; in bed, pain in abdomen, etc.; in bed, colic; hoarseness ; after rising, dry cough; on rising from bed, indolence, etc.; on waking, general sweat.
• ( Afternoon ), About six o'clock, anxiety, etc.; towards evening heartburn; about five or six o'clock, vomiting, etc.; towards evening, colicky pains, etc.
• ( Evening ), Dullness of mind, etc.; pressure in head; headache; frontal headache; heaviness of lids; in bed, on closing eyes, pain in margin of lids; in bed, toothache; especially on rising from sitting, tearing in abdomen; desire to take deep breath; especially while writing, pain in chest.
• ( Night ), Delirium; irrational talking, etc.; sneezing; nausea, etc.; vomiting; urging to urinate; pain in left shoulder, etc.; swelling of hand, etc.; biting, etc.; on cheeks, etc.; itching on hand; itching on foot; sweat.
• ( Midnight ), Cough.
• ( Bending backwards ), Headache.
• ( Bending forwards ), Pain in sternum.
• ( After dinner ), Pain, etc., of stomach; bruised pain in epigastrium; sensation in heart, etc.; yawning.
• ( Drinking ), Vomiting.
• ( While eating ), Stitches in side.
• ( After eating ), Nausea; fulness of stomach, etc.; while sitting, not while standing, food presses in stomach; cough; sleepiness.
• ( Excitement ), Feeling in ears, etc.
• ( Expiration ), Stitches in side of abdomen.
• ( Heat ), Headache.
• ( On laying one leg over the other ), Cutting in thigh.
• ( Movement ), Headache; pain in abdomen; tearing, etc.; in back; pain in small of back; aching in thighs, etc.
• ( Music ), Apprehensiveness, etc.

SUPPLEMENT: DIGITALIS. Authorities.

96 , Bull. de Thérap., vol. lvi, p. 101 (Brit. and For. Med.-Chir. Rev., 1860 (2), p. 380), a woman, æt. twenty-seven years, for swelling of the limbs, took a large quantity of freshly-expressed juice; ( 97 to 100 , Sharp's Essays on Medicine, tenth edition, 1874, p. 717); 97 , 1 drop of 1st (cent.) was taken, repeated after six and twenty-one minutes; 98 , 2 drops tincture (equal to 1 drop of sap of plant); 99 , 6 drops of tincture; 100 , 8 drops of tincture; 101 , Dr. C. Kohnhorn, Deutsche Militaire Zeit. (Lancet, 1876 (1), 582), a recruit, æt. twenty-two years, ate Dig. pills for some time to escape service, death; 102 , T. D. Nicholson, M.D., Month. Hom. Rev., 1876, p. 766, experiments; 103 , Dr. P. K. Guild, Pub. of Mass. Hom. Med. Soc., vol. iv, p. 30. Mrs. H., for a cough, drank freely of a tea made of Digitalis instead of Mullein.

MIND

• Intellect destroyed, 96.
• Coma (fifth day), 96.

HEAD

• Dizziness, 101.
• Headache, 101.

EYE

• Conjunctiva anæmic, 101. [1090.]
• Dimness of vision, 101.

EAR

• Noises in ears, 101.

FACE

• Face pale, 96.
• Lips anæmic, 101.

MOUTH

• Gums anæmic, 101.
• Tongue moist, with grayish-white coating, 101.
• Tongue thickly coated, 101.
• Tongue white, 96.
• Breath fetid, 101.

STOMACH

• Complete loss of appetite, 101. [1100.]
• Heartburn, 101.
• Frequent singultus, 96.
• Very distressing nausea, together with a headache, and flashes of light before her eyes, 103.
• Violent sickness (immediately), 96.
• Occasional vomiting, 101.
• From Wednesday until Saturday night she had not been able to take any food or drink, or drink, or to sit up much of the time, 103.
• Epigastrium painful on pressure, 96.
• Great tenderness over the stomach, 101.

STOOL

• Diarrhœa frequent, 96. [1110.]
• Constipation, 101.

URINARY ORGANS

• Decided action on the kidneys, shown in increased secretion (after one hour), 97.

SEXUAL ORGANS

• Menorrhagia, 96.

HEART AND PULSE

• Great commotion of the heart, a great throbbing and pounding as she expressed it, 103.
• In two experiments with Digitalis tinct., I have observed the pulse slightly retarded, but it fell three beats in an hour after taking 6 drops, in drop doses, every ten minutes, and only two beats after 20 drops in 3-drop doses. In two other experiments the pulse had not varied more than one beat per minute during the hour. The pulse varied so much after taking 1st dil., that no conclusion can be drawn as to its action. The sphygmographic tracings show but little change, 102.
• Pulse 72 (before taking); 73 (after two minutes); 74 (after four minutes); 76 (after six minutes); 74 (after ten minutes); 72 (after forty minutes); 66 (after sixty minutes); 64 (after eighty minutes); 72 (after one hundred minutes), 100.
• Pulse 64 (before taking); 68 (after five minutes); 72 (after ten minutes); 68 (after fifteen minutes); 64 (after fifty minutes), 98.
• Pulse 66 (before taking); 68 (after two minutes); 67 (after four minutes); 66 (after six minutes); 67 (after eight minutes); 68 (after ten minutes); 66 (after fifteen minutes); 63 (after twenty minutes); 64 (after twenty-five minutes), 90.
• Pulse 80 (before taking); continued the same for five minutes; 76 (after seven and eight minutes); 78 (after ten minutes); 76 (after twelve minutes); 78 (after fourteen minutes); 80 (after sixteen twenty and twenty-one minutes); 76 (twenty-second to twenty-fifth minute); 78 (after twenty-seven and twenty-nine minutes); 80 (after thirty minutes); 83 (after thirty-two minutes); 84 (after thirty-four minutes); 85 (after thirty-six minutes); 84 (after forty minutes); 80 (after sixty-three minutes), 97.
• Pulse slow, 96.

GENERALITIES. [1120.]

• Convulsion, 101.
• Exhaustion (fifth day), 96.

SKIN

• Skin pale and ashy gray, and parchment-like, 101.

SUPPLEMENT: DIGITALIS. Authority.

104 , Drs. Flechner, Frankel, Schneller, and Winternitz, Zeit. der k. k. Gesel. dur Ærzte zu Wien, 1847, p. 171, three men made a proving with the tincture, beginning with 2 drops and increasing to 160, and in one case to 400.

• The small doses up to 30 drops, produced scarcely any effect except a bitter taste and some eructations; larger doses caused in two persons dryness of the lips, a feeling of rawness or burning in the pharynx, visible increase of saliva and mucus in the mouth, nausea, inclination to vomit, and a constrictive pain in the throat and along the œsophagus, with rumbling or griping in the intestines, and tension caused by flatulence; the stools remained unaffected in two provers, but in one became very dry and indolent, and in another, after 80 drops, there was sudden diarrhœa. The symptoms from 100 drops and upwards, were pressive pain in the forehead, obscuration of the eyes; in one case, oppressive pain beneath the ensiform cartilage, 104.