Rumex crispus

por Richard Hughes & Jabez P. DakeA Cyclopaedia of Drug Pathogenesy

Volume III — Main text

RUMEX.

Rapux erjjpiu, L. Curled dock, yellow dock. Nat. Ord., Pofygonacea,

I. Provings. — I. a. Dr. H, A. HoucHTON, at. 24, in perfect health, save for some acne on back, proved a tinct, made from root and leaves. Nov. nth, 185 1, took 6 dr. of ist dil. inc. 12th. — Dull heavy headache from 10 a.m. till n., less severe after 2 p.m. 13th. — Slight headache during d, 14th and 15th. — No symptoms. i6ih. — Repeated dose in e. Very restless during n. ; dreamed of seeing friends. Heat and other symptoms of fever towards m., followed by sharp pam in abdomen increased by deep inspiration, which entirely subsided on rising. lyih. — Dull heavy headache during d., less severe p.m. ; legs feel very weak when going up and down stairs in e. i8th. — Sharp cutting pain in 1. breast came on at noon, and lasted an h.; dull heavy headache during d. J9th, — Slight headache. 2oth — 25th. — No sym- .ptoms. On latter d. took 10 dr. of same in c. 26ih — 29th. — Nosym- 'ptoms. Repeated dose on latter in e. 30th, — Great coldness of lower extremities during forenoon. Repeated dose on going to bed. Again restlessness and dreams of friends. Dec. 1st. — Great coldness of Tegs as before ; in e. cutting pain in abdomen^ followed by diarrhceic stool; legs weak again on stairs. 2nd. — Scraping in throat, with slight catarrhal symptoms, in e. N. as that of 30th — ist ; cold clammy sweat on legs during greater part of it, followed by symptoms of a severe cold with cough, which lasted during 3rd. 4th and 5th. — No symptoms. Repeated dose on latter e. without effect save restlessness on following n. 7th. — Repeated dose in c. Cold legs a.m. as before, also weakness in them ; dull heavy headache with deep-seated soreness of eyes during d., worse a.m. 9th. — N. as before -, headache as yesterday and weakness of legs. loth. — profuse perspiration on legs during latter part of n. nth. — Aching pain in anterior part of lungs, coming and going several times in afternoon. Throughout proving bowels more or less constipated.

b. Dec. 27th. — Took 15 dr. of tinct. in e. Sleep, head and legs affected next d. as before, 3 n. following being very restless. 29th. — Dull pain in abdomen before rising, continuing a short time thereafter, and followed by a diarrhceic stool; slight headache during d. 30th. — Sticking pain in 1. thoracic region in m. before rising, followed by dull pain in lungs; slight itching of legs in e. Jan. ist. — After being costive for 3 d., this m. before rising sharp pain in lower abdomen, followed by two diarrhoric stools, after which dull pain in abdomen lasting 2 or 3 h. Felt weak this d. and next, on which latter he had dull headache during forenoon. Again constipation for 3 d., followed by natural stool on 4th, On 5th had a good deal of dull heavy headache, and epistaxis occurred on slightest picking of nose. On 7th,*in e., repeated dose. Headache and constipation during next 3 — 4 d. were the only appreciable effect. On 16th, bowels having been regular for 3 d.^ took 20 dr. in e. Headache, weakness in legs, and some borborygmus and colic, with constipation, followed as before y and on 30th he notes that the pain in anterior chest has harassed him again, d.

and n., for 5 d. past. It was accompanied by some headache and pain in stomach, also with belching of wind.

Four d. after taking xst dose of tinct. (Dec. 3 ist) he notes that baclc and shoulders are densely covered with small red pimples. This eruption continued till 5th, when it is said to be gradually disappearing. Itching was slight, and mainly felt on exposing back to air, as in undressing for the n. After 2nd dose eruption came again, with a few pimples on chest and, later, on limbs. The same thing followed 3rd dose, but thighs were this time thickly covered. [Phil, Journ, ofHom.y ii, 706.)

  1. a. Dr. £. M. Kellogg, xt. 26, proved a tinct. made with equal parts of expressed juice of root and alcohol.''^ He was in perfect health and with no tendency to symptoms observed. March 30th, 1852, put I dr. into half a tumblerful of water, and took a tablespoonful on retiring, repeating dose each m. and c. till whole solution had been consumed. 31st. — Two h. after breakfast felt as if food had not digested. Unusually irritable temper. April 1st. — Like feelings after break^t ; in e. great lassitude and uneasiness, with stagnation of ideas and indifference to surrounding persons and things. 2nd. — lo a.m., slight dull frontal pain, with indisposition to thought. 12 m., great irntability of temper \ muscular pain in thighs and legs, slightly increased on pressure. At 2 p.m. on this d. and last voice suddenly rose several notes in pitch, and bo continued for about ^ h. ^ to*day at 4 p.m. it sounded as if he had a cold in head. 7.30 p.m., very thirsty (unusual) ; great lassitude and weariness, with somnolency ; shifts position constantly; legs feel tired^ though he has done but little walking to-day; feet tender, with extreme sensitiveness of and shooting pain in corns ; dull transient pain in teeth. 3rd. — Some coryza and obstruction of voice ; dull aching pains in legs all d. 4th. — Slight coryza and pain, p.m., especially in r. leg. 5th. — Dull heavy feeling in head during e. ; less appetite than usual. After retiring, late, lancinating pains in lower jaw at root of 1. canine tooth, and slight headache. 6th. — P.m., urine less copious than usual, red and turbid, with flocculent deposit and oily surface ; thirst during e. 7th. — Brick-dust sediment in urine, very marked and heavy. 8th. — Slept very uneasily ; many kinds of dreams, magnifying trifles, disturbed him. Woke feverish, having frontal headache, dull and constant ; heat of skin ; full and frequent pulse; this was followed by sensation of cold, yet not a regular chill. Tongue coated white ; slight nausea while dressing, and vertigo compelling him to lie down again ; throat sore, with feeling as of lumps there when swallowing ; thick yellow secretion from posterior nares ; great pallor of face while standing. Fasted all d. till e., feeling empty and sunken, but without appetite ; considerable pain in back p.m. and e. ; "rheumatic" pains in front of both tibiae in e. 9th. — Slept well ; woke in perspiration, free from pain save in r. shoulder, and here it passed ofF in 2 h. There now came on a hemorrhoidal attack, with much itching of anus, and also of prepuce, which lasted after piles had receded. Appetite returned from 9th, and became even exaggerated.

h. Same, June ist, put i dr. of 3rd dil. in half a glassful of water, * With such a tincture all the subsequent provings were made.

and cook a teaspoonful m. and e., repeating it twice or three times daily up to 6th. On 1st no symptoms, save heavy feeling in head during e. 2nd, — Woke with bitter taste in mouth. At 1 1 a.m. voice assumed nasal tone for a short time. On 3rd felt languid and weary (a very warm d.). On 5th, rheumatic pains in shins. On 7th, dull pains in stomach ; coryza with yellow expectoration from posterior nares. On 8th took 6 pellets of 6th dil, at midnight, repeating dose next m. at 9. Irritable temper ; during e. feeling of soreness and excoriation, with redness, at end of prepuce. loth. — All m. feeling of rawness in upper throat, with secretion of phlegm. Repeated dose at i p.m. Increased redness, with itching, on prepuce. At 7.30 p.m. slight frontal headache, with shooting pains, nth. — Took dose at 11 a.m. Preputial troubles and slight frontal headache continued this d. and next. On 13th took another dose, and had epistaxis, tenderness of feet, and scanty stool. On Sept. 20th resumed use of 6th dil., taking 6 globules that m. and next m.and e. 2ist. — P.m., weariness ; aching in bones of legs. 22nd. — Rose in m. with bad taste in mouth and slight feeling of oppression in head. Took dose that e., and repeated it daily till 27th without further effect ; save that for several n. afterwards eyes felt as if lids were inflamed and dry (no visible signs of inflammation), and that on Oct. 4th he had a slight liquid motion at 4 a.m., desire for which was very urgent and woke him from sleep. {Ibid.^ p.71 1.)

  1. a. Dr. JosLXN, June I2th, 1845, took 6 glob, of I2th dil. at 10.45 a.m. In 10 m., pain at lower border of 1. axilla ^ empty eructations after dinner, with pain in r. hypochondrium ; pressive pain in one ear while walking. 13th. — Repeated dose at 8.45 a.m. At 11.10, shootings in 1. chest, just below middle, at angle of a rib. 14th. — Took 6 glob, of 6th dil. m. and e., without effect. 15th. — Repeated dose at 8.5 a.m. 4.30 p.m., pain in acending colon while walking. 7 and 10, pressive pain in dorsal spine. JO.20, pressure in r. occiput and temple. 11.15, pressive pain near inferior angle of r. scapula. i6th, — Repeated dose at 10.20 p.m. Next m., just after rising, pressive pain in r. ear. 10.45, remittent pain near insertion of r. deltoid. 10.50, pain at inner side of arm. ii, great propensity to sleep.

b, Sept. 23rd, 1850, took 4 glob, of 12th at 10 a.m. Soon burning smarting in upper larynx and in fauces, much mucus secreted there ; irritation and expectoration also referred to some of the 1. bronchial tubes. Feeling in larynx continued for 2 h, considerable, and could be reproduced the whole d. afterwards by impulse of expired air on part. 10.47, occasional pain in forehead and r. temple. 11. 10, cough excited by tickling in 1. chest. Late in e., rheumatic pain just above wrist (dorsal aspect). 11 p.m., hoarseness. 24th. — 12.20 p.m., cough excited by tickling behind sternum. Repeated dose at 10.15 p.m. 10.38, severe transient sub-burning pain at 1. superciliary ridge, and, ] m. later, at r. 1 1.5, umbilical pain, with nausea, eructations, and shooting over 1. eyebrow. 11.25, hoarseness, commencing suddenly. 1 1 .30, pain at small spot in urn bilical region, first felt on yawning, and for some time after reproducible by deep inspiration. 25th. — 2.40 p.m., while lying (on r. side) after dinner, severe but transient shooting in 1. chest j 8.30, hoarseness commenced again. 26th. —

Repeated dose at 9, and (no symptoms having occurred) 9.30 p.m. 943, on beginning to walk (in room) fine shootings in back, midway between dorsal spine and 1. side, then in spot in I. lumbar region. 10.23, ^^^ shooting in r. eyebali. 27th. — Hoarseness again in e. ; cough on lying down in bed. 28th. — Aching, burning, sticking pain immediately below middle of 1. clavicle, felt only when riding in open air, a.m. ; cough on lying down after dinner, and again at n. on turning from back to 1. side. 30th. — Cough when riding in open air, excited by tickling behind mid-sternum, and followed by easy expectoration, a.m,

c. Nov. I2th. — Took 6 glob, of 12th at 9.20 p.m. 10.35, slight dull pain at and near umbilicus, with slight nausea. 1 1 — xi-30, pressure as if from end of finger between clavicle and axilla, alternately on r. and 1. side of chest, several times ; followed by dull aching under middle of 1. clavicle. Next d. a fluent coryza set in, with — later — cough and hoarseness. These were still present when, on the 19th, he repeated dose) but as nothing is noted after the 23rd, he was presumably free when, on the 26th, he took 8 glob, more at 9.6 p.m. 9.16, increased flow of saliva. 9.26, zincky taste on tongue and hard palate. 9.30, pain in stomach and abdomen, with slight nausea, q.37, pain in r. temporal region. 9.40, sudden and severe itching of upper lip, near 1. side of nose. 27th.— Slight sense of fulness in head, with lack of cheerfulness, but without much real depression ; cough from tickling in chest, m. before breakfast ; very sudden and urgent desire to urinate, urine extremely pale,e. 28th. — In n., discharge of mucus from posterior nares and aching in 1. instep. 29th. — Recurrence of itching of upper lip. Dec. 2nd. — Inn. cough from tickling behind upper half of sternum. Vivid dreams this n. and the following. Several d. about this time had vesicles on upper antero-lateral aspect of neck, near jaw ; also flatulence.

d. Dec. 24th, at 8.40 p.m., took dose of 30th. 8.50, pain over 1. eyebrow. 8.53, sensation of heat in cheek. 9.10^ same on back and face, oppressive in former, smarting in latter. 9.20, rather chilly, especially in back ; and 3 m. after chilliness had commenced some pain in abdomen, with slight nausea, and shooting near middle of anterior part of chest. Slight pains and itchings here and there followed. Next m. on waking there was dull aching in forehead, reddish-brown dry coating on tongue, and bitterish taste in mouth. About noon, cough and piercing in 1. lung on breathing cold air. Nothing further of note occurred. May 25th, [852, he again took 30th, repeating it 8 times at i h. intervals from 7.15 p.m. Nothing followed but the slight achings and itchings here and there, with tickling at throat-pit and behind sternum. On 26th took same^ with still less result.

e. May 27th, took 6 glob, of 3rd dil. at 8.30 p.m. 8.38, shooting, like a slight electric shock, from rectum to I. groin. 8.45, itching deep in meatus of 1. ear. 8.53, severe and continued itching on back between scapula?. 9.27^ dull pain at inner side of 1. leg at each step in walking, soon followed by sharp pain at inner side of r, knee. 10, chilliness. 28th, — Woke in n. with pain in cardiac region of chest.

1 1 .8 a.m., stitch-lilcc pain at inner part of r. knee, on stepping. During d. depressed and indisposed to exertion j burning pain in region of heart at times, which in e. and early n. became continuous and strong, with frequent and severe, but transient, exacerbations. {Jhid.^ i, 294.)

  1. Dr. B. F. JosLiN took, June 12th, 1845, 6 glob, of 12th dil. at 1.45 p.m. After about 2 m., sharp pain in upper r. chesty near axilla. On 13th took same dose without effect. On 14th took 6th dil. m. and e., and repeated it at 8.5 a.m. on isth. 8.50, colic near umbilicus. 9i pain in sternal region. (Jhid.y 304.)

  2. Mrs. P — , aet. 43, Sept. 24th, 1850, took 3 glob, of 12th ac 10.25 p.m. 10.29, pain in 1. shoulder, and from it along upper arm to elbow, with sense as if arm had been strained. On 26th, at 9 p.m., repeated dose. In 4 m., aching at I. of dorsal spine extending halfway to side, lasting 4 m. j about same time hacking cough from irritation behind sternum, which about 5 m. from its commencement became very frequent. In 22 m. sharp momentary shooting at seat of aching. 9.48, numbness of r. hand. 10.2, cramp-like pain at I. nape. (Ibid.)

  3. a. Dr. M. J. Rhees, ret. 34, strong and well, took, Oct. 1st, 1 858, at II p.m., I dr. oftinct. in 3j of water.* Sensation across forehead as if brain were loose when moving head, and as if it were bruised, commenced 2 m. after dose and lasted till after breakfast next m. After 2 h., slight numbness and crawling sensation in I. arm (in bed). 2nd. — 8.30 a.m., repeated dose. After 3 h., grumbling stinging toothache in r. upper molars, while riding in cold wind, with dull aching in forehead ; sharp piercing pain in 1. head for short time. 3} h., dull pain and sense of fulness in 1. iliac region while riding, lasting 2 h. 4 h., rending in front of both ankles running along instep, alternated several times with gnawing pain in internal condyle of 1. humerus ; after which, aching and heaviness with crawling sensation all through lower extremities — while riding. 6 h., burning tingling pain below and to I. of r. nipple. 8 h., copious discharge of colourless urine. 7,30 p.m., repeated dose. 15 ni., sense of epigastric distension, with much tasteless eructation ; heaviness in 1. calf, as if flesh would fall from bones j dull aching in both elbows. ^O m., languor and general heaviness, with fulness of head and chest \ crawling tingling in lower limbs, I h., dull aching low in occiput and in r. temple ; aching and pressure at vertex. 2 h., boring pain behind 1. car. 3 h., fulness and aching through sinciput and temples. 3rd. — 9 a.m., repeated dose, 10 p.m., aching in r, hip-joint while walking, producing slight lameness, followed by burning pain on small spot near top of r. sacro-iliac symphysis. II, in act of lying down, sudden burning-stinging pain in whole 1. chest when inspiring. Next m., rending aching pain in bend of 1. knee while standing. 4th. — At 10 p.m. took 10 dr. in -^j of water, I h., stinging burning just below inferior angle of!, scapula, followed and accompanied by stinging, almost itching, pain in 1. chest, just below nipple, with heavy tnrobbing in cars synchronous with pulsations of heart. Dryness of mouth and tongue at n. 5th. — 8 p.m., sensation in bowels and rectum as if diarrhoea would ensue, for 2 — 3 h. II, repeated dose. 30 m., sensation as of lump or ball in throat, not

• la all these doses lao succussions were given to the solution.

relieved by hawking or swallowing. Restlessness and discomfort in bed at n., position must be frequently changed ; burning pain in 1. chest, just below nipple, worse when inspiring deeply. 6th. — 2 p.m., throbbing through whole body ; all d. sense of great dryness in nose, front and back. 7 p.m., itching in bends of elbows and at same time over heart, with aching under and below apex of 1. scapula, xo, repeated dose. 10.10, drawing pain, almost a cramp, in r. calf, continuing J h. Sensation in 1. chest as if heart suddenly ceased beating, followed by heavy throbbing through chest (this has been felt several times since beginning of proving) ; aching between scapulas while standing, also stinging burning there, attended by constant desire to inspire deeply, with sense of dry heat in middle of chest, — the inspirations are attended by dull heavy pain in region of heart ; stinging pain on inner side of r. upper arm *, sensation as if ears were ol^tructed, especially 1., — prover's own voice, as well as that of others, sounding strange to him, producing a kind of titillation in ear and having a peculiar ringing confusing sound, while yet sense of hearing is as acute as ever (this began 6 h. after last dose, and continued 18 h.). Complete loss of sexual desire for several d. At to p.m. on 7th took 20 dr. Symptoms of ears and voice still continued, though in less degree, into following d., attended by slight ringing in ears, which on 9th became constant roaring as from a shell, with feeling as if a fine thread were tied tightly round neck just below ears. All this continued for a week, and then gradually died away. Roaring was not relieved by pressing finger into ear.

b, Nov. 22ndj took 5 dr. of 6th dil., prepared as before, at 10 p.m. After a few m., dull bruised feeling in forehead, most severe on r. side, worse on movement, when it feels as if brain were loose. This continued till next m., when it was even more marked. P.m. on 23rd, for 2 — 3 h., severe stinging pain in region of heart, extending through chest to point of ). scapula, with frequent desire for deep inspiration, which yet increases pain. At 10.30 p.m. took 10 dr. In i h. sensation in bowels as if diarrhoea would come on, with aching in rectum. 24th. — Dull aching in r. molars, upper and lower, relieved by dinner, violent irritation to cough while eating, observed at each meal \ at 4.30 p.m. pungent drawing pain in 1. occiput, with similar pain in 1. nostril and feeling as if coryza would ensue. Much tough mucus in larynx, with constant desire to hawk and raise it, but without relief, worse at n., but troublesome all d. At 11 p.m. took 15 dr. 25th.— Dull headache and slight bruised feeling in forehead nearly all d. ; again sensation in bowels as if diarrhoea would come on, with the aching in rectum. At 11 p.m. took 20 dr. Frontal aching increased soon after, with pungent tingling sensation in occiput. After | h. tingling crawling sensation in lower extremities. 26th. — After breakfast, griping below umbilicus, relieved by emission of very offensive flatus ; dull pain in region of heart, with same and also weight in 1. upper arm, especially elbow. In c., aching in throat, as if lump were sticking in gullet -y feeling as if thread were tied tightly round neck just below ears, with slight roaring in these ; frequent forcible eructation of tasteless flatus i aching in pharynx and collection of tough mucus in feuces.

with slight irritation to cough. At 1 1 p.m. again took 20 dr. 27th. — During stool prickling itching on buttocks (also on following d.) •, after singing in e. dull frontal ache with heat and redness of face, which went off on repeating dose at 10 p.m. 28th. — Much tough mucus in fauces, which is very difficult to eject, raw pain while doing so under each clavicle ; at n. raw stinging at mid-sternum, a little to I. ; after lying down in bed dull pain in 1, side near back, Just above last true rib j this happened again on following n., which was very restless and dreamful, as were all up to that of Dec. 6th. On that of ist burning stinging pain near heart returned, it gradually moved to l in. above and to 1. of nipple, and continued some time, increased on deep breathing and by lying on back or r. side, relieved by lying on I. side. During this d. severe aching in r. molars, relieved by rinsing mouth with cold water ; itching on buttocks and calves. Sexual desire again diminished during this proving. (Amcr. Horn, Rrv*^ ii, 69.)

  1. a. Dr. H. M. Paine, a;t. 28, took 10 dr. of tinct., and after J h. had cutting pain at pit of stomach for 5 m. while riding in open air. No other effect followed this dose, or one of 6 dr. taken 2 d. later. Twelve d. later took 10 dr. again, and 15 dr. next d. On ist d. felt unusually sensitive to cold; on 3rd d., at 11 a.m. and 8 p.m., darting pain inl, head for 4 h. ; during 4th d. burning pain in stomach and abdomen, and at 11 a.m. dull aching through forepart of head; also acute momentary pain at pit of stomach. Seven d. after he took doses of 10, 15, and 20 dr. during 8 d. with no result save a burning pain at pit for a short time after the first. He now, 2 mo, later, took repeated doses of 10 and 15 dr. for 34 d. On 2nd d. he woke about 2 a.m., had soreness for few m. in whole 1. chest after turning to that side, and slight pain in head before breakfast. On 3rd d., at 7 a.m., deep inspiration caused stitches round waist, and at one time p.m., while riding, a very acute stitch along 1. margin of sternum. On 6th d. acute lancinating pain a little to 1. of sternum and under I. breast, and at 3 p.m., white writing, fine stitches for a while in substance of I. lung. On 7th d., while at dinner, momentary slight stitch at lower edge of 1. ribs i frequent small passages of fcEtid flatus at n. On 27th and 35th d. momentary shooring pains in various parts of chest during e. On 7th d. frequent desire to urinate j on 8th desire less frequent but more urgent; and same urgency recurred on 19th, 20th, 27th and 28th d. On 2nd n. unpleasant dream of murders ; several such, of accidents, losses, &c,, during 6th n., and again on several other n. up to the 29th. On e. of i8th d, his attention was called to an eruption then getting troublesome, though he remembered it had been present most of the time, composed of very abundant minute red pimples situated on lower extremities — especially on posterior surface and inner side of knees ; it caused from this time violent itching on undressing at n. ; by 24th d. scratching had developed many little pustules, most numerous about knees, at which point eruption lasted longest j itching was felt occasionally at other times, and once on arms also; scratching relieved it much, though causing some burning.

l>. Two years later. Dr. P — recommenced proving, taking 10 dr. of tinct, at i p.m. on Feb. 7th without effect. 9th, — Repeated dose

at 10 a.m. and 9 p.m. For 2 h. after former sensation as of hard substance in pit of stomach. loth. — At ro a.m. took 10 dr. During d. frequent inclination to urinate, with feeling as if urine could not long be retained. While undressing at n., and for some time after, considerable itching on lower extremities ; this recurred following e. i6th. — At 9.30 p.m. 10 dr. 17th. — After 4 a.m. very unpleasant dream of burglars. Repeated dose at 7,30 a.m. and 9 p.m. Itching of legs again felt in e. as before. Sleep disturbed ; wakeful and restless ; short naps, and unpleasant fancies even in waking intervals. Took another dose at 9 p.m. 19th. — Itching of extremities began about i h. before retiring last n., and again on waking this m. Nothing is visible till after scratching, when a temporary diffused redness appears. For several d. unusual sensation of heaviness in epigastrium, occurring immediately after eating and lasting J h. (Trans, of Amer, Inst, of Horn, for 1858 ; and Jmer, Horn, Rev., ii, 33.)

  1. a. Dr. W. E. Payne took 15 dr. of tinct. one e. After 10 m., weight in stomach, as from undigested food, pressing upwards as far as throat-pit, — this sensation continued (for an h.) till he fell asleep. In m. on waking felt nauseated, with movement in intestines as from a cathartic. Took 5 dr., whereupon weight at epigastrium recurred, but it was not so great, — rather^a sensation as of a hard body there ; it was somewhat increased by food, and continued for 4 h. Three d. later he took 6 dr., when same sensations came on ; feeling at throat-pit descended towards stomach at every empty swallowing, but immediately returned ; after lasting 2 h. this condition gradually abated, but returned after dinner and continued 2 h. or more.

h. Dr. P — now took repeated doses of 10 dr. of ist dil. during 6 d, (none on 4th d.). On 2nd d, recurrence of sensation at epigastrium &c., 15 m. after taking drug. On3rdd. aching and sense of great ^fatigue in loins, also of lassitude in lower limbs and aching in calves, as after long walking or standing, worse when moving, relieved by lying down. On 4th d., m., sore pain at l.sacro-iliac juncture, increased by stooping and rising ; in a few h. pain became general over loins, and felt like that resulting from a strain, — it was increased by any sudden movement ; p.m. it somewhat abated, and was succeeded by pulsative sensation in muscles of nates. On 7th d. awoke with bruised sensation in brain, increased by moving or stooping; it continued until noon, and suddenly disappeared after dinner.

c. He last took 3rd dil., repeating it 2 d. later. Previous sensation of undigested food recurred 3 h. after ist dose, continued (after a 2nd dose) through afternoon, but went off in n. On 3rd d., after i h. sudden and prolonged sneezing. On 4th m., after stool, which was diarrhceic, relaxed sensation with rumbling continued for some h.,as if another evacuation would follow. Nothing occurred, however, till 5th d., during which he had 5 copious li^id stools, with colic pains just above hypogastrium, disagreeable rumbling in bowels, nausea and loss of appetite ; motion would pour away in full stream, as if a large quantity were coming, then be suddenly arrested, and inclination go off, but on rising the urgency came on again, and on returning to cabinet a fresh stream poured forth. Besides the actual evacuations, there were frequeat

urgings during d., which, however, could be restrained. (He had awaked this m. with acid stomach and eructations of sour Hatus.) On 6th d. there was still nausea and want of appetite. (Trans, of Amer. Inst, for 1858.)

  1. Dr. Clarh Wright took two doses of 6th dil. In 3 d. he was attacked (with, out cause) with a severe cougti, such a^ he bad never bcfoie experienced, dry and spasmodic at fiFM, coming on in paroxyiims preceded by ilckHng in throat-pit and attended with determination of blood to and slight pain in head and wrenching pain in r. chest; the motU violent paroxysms occurred a few m, after lying down at n., and lasted 10 — 15 m. This itatc continued about i weeks, when expectoration of adhesive mucus, in Mnall quantities, nci in, and lasted a formight more. Some medicines were taken in latter stages of cough, without obvious rcsultii. {Ibid.j i860.)

  2. Df. B. F, Bow£R5, Nov. »6th, i860, took a few pellets of nth dil. at JO p.m. Woke next in. with pain in bowels, relieved by emission ot flatus; pain also below and anterior to nipple, mostly r., and in larynx, mostly 1. There was during d. borborygmus anil enictation ; itching in anus; headache with coryza and hawking of mucus from larynx : in c., burning of palms, Dec. 3rd.— Repeated dose at 9 p.m. In -j m. itching at various spots ; 7 m., eructation ; 1 1 m., hacking cough ; also burning of palm« again, and ringing in ears. Troubled dreams at n. On waking in m. flatulency, with sensation in tongue and mouth as it burnt. a4th. — At '8.4.0 p.m. look 30th. During next h. experienced a few of foregoing symptom-s especially flatulence and itching^ j alMi sense of brt3ttile»>ne)ts. On another d. took nth dil. at 9.10p.m. In fir>t \ h. felt vertigo, pain above umbilicus, borborygmui, eructation, yiwnmg, flow of saliva, hawking o^ mucus. At 10,10 pain over r. eyebrow } at to.%) hiccough, pain in 1. temple, itching in I. tAdt of face; at 10.35 (p^in in eyebrow continuing) sensation of stoppage in 1. ear and return of burning in palms. {Afntr. Horn. Rtv., ii, 51.)

II. a. VV. Kelly, a:t. 18, sound and vigorous, proved under direc tion of Dr. H. C. Preston. He took daily doses of tinct. (4 p.m.), 5 dr. on 1st d., 10 dr. on 2nd, 3rd, and 4th, 5 dr. on 5th, t dr. on 6th and 7th d. After the 7th d. his distress augmented so much that he was unwilling to continue the proving ; and the evolution of symptoms went on tor 15 d. more. The action of the drug was chiefly characterised by pains, numerous, varied, and of frequent recurrence, from which hardly any part escaped. They were all transient, intervals occurring of 10 m. — i h. Some were so severe that prover asked for an antidote ; and they mostly prevented study, though not active occupation. They ceased about li a.m., and recommenced a few h. or less after 4 p.m. dose.

b. From 1st to 9th d. his nights were very restless, sleep broken and unrefreshing, or disturbed with vivid dreams ; he jumped and tumbled in bed, walked about room, and talked in sleep. Dreams were extraordinary and terriflc. On 9th d. they were pleasant, and on loth he slept well. Several times during 1st d. there was dizziness. Three h. after talcing ist dose head began to ache, and ached severely till he went to sleep, towards midnight ^ it returned on waking, and continued till noon next d. Headache was dull on 3rd d., very severe 5th — 9th d. i it most frequently afl^ected the temples, but was twice felt in occiput, twice over r. eye, and on I2ih d. in forehead.

c. On 2nd d. there was nasty taste in mouth, and tongue was heavily coated. On 3rd d. pains were severe in gastric region ; on 4th dull and heavy, towards cardiac orifice i on 5th severe on waking in m., and frequent, tongue again heavily coated. There was tickling in throat soon after taking drug, and throat then became a little sore.

On 6th d. pyrosis after dinner ; constant inclination to urinate. On 8th d. pains severe in stomach ; throat dry, and deglutition difficult ; anorexia, constipation. On 9th d. same dryness of throat ; on loth hoarseness ; on i ith pain in stomach on waking (3rd d. of constipation) ; on 1 2th anorexia.

All the other symptoms belong to the pains described above. (United States Journ, of Hom,^ i, app., 27.)

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