Plantago major

Volume III — Main text

PLANTAGO.

Pia/if ago major, L. Greater plantain. Nat. Ord., PiarttagiHOcne,

I. PnrvirtFi.'~i. Dr. Frestier proved tinct. of whole plant.

a. He touK, one m. at 7.30, 1 dr. in water. During d. griping with (inodorous) flatui, A little after retiring to rest at n. was suddenly wakened by uigent call to stool, of quite unprecedented intensity. Passed matter at fint soft, then liquid, with smarting and frc^h tenesmus 4 also itching in urethra and much borborygniui. After 3 h. sleep awoke with repetition of same in every particular, and the tame thing occurred at 6.30 a.m. During d. he bad 3 more stools, at 10 a.in., 7 and 8 p.m., followed by great weakness.

h. Some week?i later repeated dose at 7 a.m. At ii| griping and very soft stool. Craving for food not long after J^eumrt making him anticipate hour of dinner. For re^iof d, slight borborygmus, dryness of throat, thir^, and no further appetite for food. After a good n. sudden waking with desire for stool, as before i stool loose, without tenesmus} Might smarting along urethra during paa&agc of urine } nausea alternating with desire for food; eructations with odour of roneu e^gs (he had eaten none). He had 3 more stools at hourly intervals, quite liquid, without ^ma^ting or tenesmus, but showing numerous albuminoid 6a)crt, like thane of cholera. At 9,30 p.m., after somewhat tiring mental work, lassitude fultowcU by general heat, pulse loo, moderate headache. An h. later, after a 7th evacuation in all respects like the others, there was great decline of fever and return of appetilr. Next d. still some evidence of action in shape of a soft grey stooU. (£■//. de Lt Ste. M4d. Horn, tie France^ ii, 397.)

». a. Mr. A. Heath, Nov. 9th. ig66,took 12 dr.of nth dil., and repeated same 00 nth. On Jith, severe headache over 1. eye and side of head, with great irrita*

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tionf cannot hem being spoken to. 16th. — Took 6 dr. of 6th dil. On fraking lo m. of 18th, violent bnii&cd sort oi headache over scal^ and back of head i was unable to rest long in one place on pillow j relief for a time by resting on part in pain. On aii^t repeated dose. [Nothing noted till 14th, when a long litt of sym. ptonns is recorded, which continued to be obscrTcd, with variationsj during the next six weeks. On Jan. 8th he reports, *' All synipioras relieved or gonej" but on t3rd and 30th another batch is given, and here ihe narrative suddenly Ktous.l

1. June i^lh, 1S67, took so dr. of and dil. 14th.— 8 a.m., flight di&charge of bright blood in the siool, no pain. 9, pain over 1. eyebrow and deep in scalp, a bruised dull aching, relieved by shutting eye ; irritable feeling in head, with soreness of eyes j transient drawing pain under r. breast ; inclination to diarrhcea j feeling of nausea} coldness and shivering;. 10.45, repeated dose, ii, shivering} felt very cold. 1 p.m., inclination to diarrha;:i, with cutting pain under navel; diurrhoea with discharge of bright blootl, and jiiinful urging as if gut would protrude. [Remainder of record of this proving has been lost.]

c. June a5th, e., took 6 dr. of tinct.^ and repeated dose at 8.40 next m. 9, huskinc&s in throat, with accumulation of very tenacious phlegm j unable to clear throat, with slight sore, burning feeling. 10, bruised fcclmg, with fulncsK, in both temples i feeling of suppressed irrilability. 1.30, violent griping in bowels, causing pcrapiration, and diarrhocic stool, brown, fermented, frothy, with urging. 17th. — At 11 ajn., 5 dr. 3.8th. — Awoke with huskines^ and soreness in throat, with raw- Dc&s and irritation ; difficulty of clearing throat j feeling as if he had taken cold, 9.30, very sharp, itudden, gnping-drawing patn at 1. of navel, causing him to cry out. J. Oct. I St, at 12.30 p.m., took to dr. of iiih dil. ind.— On waking, feeling of rawness in throat xs if he had taken cold. 1 1.30, i^uddeti discharge of yellowish water from r. nostril, repeated twice within b, ; great soreness and tenderness of navel, as if ulcerated, cannot bear contact of clothes ; feeling of irritation in forehead ; impatient to get anything finished. At n. repeated do»e, 3rd, — 9 a.m., inclination to diarrhcea, with slight hypogastric cutting. At n. repeated dose. 5th. — In m. awoke with aching m loins, wor^ on movement ; l.-sided headache, mostly in temple, and bruised sensation. By midday thU feeling had spread over whole head, pain extending to top of nose j great irritability, cannot bear to be spoken to { neuralgic pain in r. face ; nausea, with inclination to diarrhoea \ cold sweat at bottom of back ; chilly feeling, with flushed face , sense of swelling about head ; least noise Kcms to go through him. Bad taste and odour of breath in m. ^ pain in head wai relieved by pressure for a few seconds, or by conuct with anything cold. Feeling in throat as of a slight swelling deep down on r. side. 6th. — Still slight headache and irritability} inclination to diarrhcea} feeling a.s if slight pressure with fingcn would sprain them. 7th, — Pain over r. kidney on waking, worse by movement. At n. repeated dose, and did so again in e. of 10th, only sMght rawness, of thrr>at with acrid expectoration having been noticed in the interim. In n, he woke with sharp attack of (r.) faceache, throat aUo being much worse. Next d. burning heat ot face ; after tea much flushed, with headache in I, temple and bruised pain in spot above eye. He continued to have flushing of face in e. for several d., and inclination to faceache, with occasional sharp anacks of it. On 15th bright blood passed rather freely at stool; this recurred daily from sist to 14th, and again about middle of Nov., preceded by a violent attack of the faceache. Much weakness was left. [These symptoms were quite different from the lung train reported a.s occurring in the fint proving, and which we have omitted.^Eos.] {HaAm. Monthly^ iii, 33s.)

1. a. Dr. Humphreys took i^dil. (manner unknown) on isi, ind, and 5th d. First n. wa:!i somewhat restless, and d., in e., some uneasiness and scraping in throat { a light supper of biscuit and tea sat heavy on stomach till late in n. (never before) j had some throbbing of arteries at n., with restlessness till la — 1 ; oppression deep in head and sense of something digging there from one temple to the other. 4tn d., unusually profuse discharge of urine. 5tb d,, woke at 6 a.ro. with severe pain in 1. hypochondrium, lasting i h. ; on rising, unpleasant sensation of bruised soreness and tension in integuments of face, especially forehead and around 1. eye, with sensitiveness on rubbing or pressure, lasting some time. At 6 p.m., while walking and driving in cool air, pain from over I. eye back towards occiput, somewhat sharp, soon passing off } slight appetite and speedy satiety ; integuments uf face and head seem unnaturally rigid. At lo p.ra. weanne&s and pain in loins and lower extre-

rnities (this also next d.) 6th d., pretty Kcvere pain fmm I. forehead deep into brain, coming on in paroxysms j unnatural sense of drynr*5 in cyclid-i for several h. ; severe painful stitches first in 1., then in r. eyeball, more al intemaJ canthus for an h. i ringing in cars; some chillinc«LS (with slight headache), cold hands and feet far some time; bleeding of gum^s, quite profuse, on retiring. 7th d., wolce with mmdc stiffness in cords ol neck (had felt same 1 m. before) j bowels uneasy, and socx qualmishnesa at breakfast, rumbling afterwards; twinges of pain, now in r. temple extending backwards, then through occiput from ear to ear, then in other parts of head, more or less severe } sharp pain in I. temple, transient (white sitting br firr after having been out) ; itching o( r, eyelid ; aching of some decayed teeth after dinner; slight appetite ; on shaving, face (which is quite tender) is observed to have an eruption of small, reddish, rough, scaly, erythematous patches, aize of pea, mi I. side only, and most near commissure of lip», — no decided pain or itching with them, but unpleasant sense.^ of tension ; tingling itching in various uncovered parts of skin all the time ; at n. many dreams, mostly disagreeable. 8th d., unpleasant sensation in bowels, yet no stool ; eruption on face less prominent, yet rough. At 10 pjn., occasional headache, 1. side, somewhat deep in brain. 9th d., at 10 a.m. Kime pain in I, head, and stiffness and itchmg of eyeballs. On loth, same headache at intervals; at 4 p.m. severe colicky pains deep beneath I. floating ribs, inci cased by deep breathing and by I^'ing on that side, continued all n. and next d„ occasional eructations without relict, nth d., stool, which on 4.th d. had been quite loose, but passed with mucli straining and eH'ort, on 8th and lotli d. absent, on 9th loose afta much uncx^iness in bowels, was this m. loose and urnnt ; painful weakness of loiiu, woTK on standing, at 10 p.m. nth d., occasional T. headache ; lips livtd, dark, and rough (thus for many d.); little appetite, with speedy satiety ; occasional sensation U if neck was stiff; lead. like heaviness of limbs at 3 p.m.; burning heat of fact, flushed after tea, with headache tn 1. temple; felt very unwell to. day. i^tbd., sometimes fleeting pains in both temples, passing in and upwards ; sexual power and desire diminished, as throughout proving, no erections for several d. ; pains through chest, more 1. side and behind ; weakness of loins after exercise. 14th d,, general depression and despondency, though weather is bright and beautiful; head clouded, heavy, and dull; pains in head, most in 1. tempoial region, ail the time, with but little intermission; rumbling in abdomen after eating ; occasional pains through both sides of chest, transient but frequently returning ; itching between fingers of T. hand, more or less constant, but worse e. and n. 15th d., 10 3.m., pains begin in head« and often centre in car, mostly I. ; soreness of some sound teeth at breakfast] colic pains while eating, not severe but constant.

b. From tasting tincture, — up to urinate twice in Crft n., and passed each time a pint or more of ligbt.cotourcd urine (never before) ; restless tossing about pretty much all n., could get no sleep till towards m. Next d, toothache on I. side^ btfore and after breakfast ; went off in forenoon, but returned after dinner for an h. or two ; again all m. 3rd d., involving sound and decayed teeth of both jaws ; again, after rising and washing, on 4th d., and, slighter, on 5tli j then no more till loth d., when it af&tcd him all m. till x p.m. There was bleeding fiom gums on sih and 6ih d., and again, after preparing some tinct. from plant, on 7th d. On 3rd d. there was painful weariness and prostration, especially in loins and lower extremities, lasting lU d. and n. j and on 4tli d. almost irresistible desire to lie in bed from general depresiioo and weaiiness. (Monograph, 1871 ; from Allen's Encyciopa-Jia.)

4^ Earhart, subject to rheumatic pains in damp weather,* took 5 dr. dosts of 1, dil. on xst, 2nd, 3rd, 4ih, 6lh, 8th, and 14th d. md d., at 6 p.m., frequent sneezing, with sanious mucus from 1. nostril j at 10, roughness and sense of rrosiun in throat i sleep somewhat disturbed with feverish tossing about. 3rd d., discharge &om 1. nostril profuse all d. ; dryness of throat in ro., went off p.m. ; frequent empty cnictations, with flatus in abdomen ; slight uneasiness in epigastrium ; pains for a few m. in upper border of r. ilium ; orgasm of blood to chest, with sensation of heat, occur* ring twice j vague pain in chest; pulse 91. 4th d., nasal discharge not so copious, but r. nostril is now affected ; occasional darting pains in head, 5th d. ; shooting pain* in I. parietal region, several times, p.m. ; drawing pain in r. malar bone, also recurring more than once ; slight pains in r. hypocbondrium ; uneasiness in bowels at 7 ajou, as

• All symptoms of this kind have been omitted.-*E08,

if he nould have to go to stool before breakfast, — also, on arising, urgent desire to micturate, with slight tenesmus of bladder, but very little urine passed. 6th d., 15 m. after dose transient dull aching deep in r. orbit j m 1 h. uneasiness in epi^astnum, with slight nausea, while walking or reading j in 4 h. shooting pain in crest of 1. ilium, recurring several times at irregular internals j after 7 h., on rising after being seated } h., chuliness with sensation of heat in chest and erratic pains in limbs, chest, and head, continuing x h., with dispositicm to stretch, hands cold in a warm room. 7th d., nasal discharge still, but not so copious or watery ; frequent shooting pains in head, mostly in parietal regions; several papules have sprung up around nose, which are red, and smart when touched. 8th d., papulx exude a yellowish humour, which soon forms a crust ; soreness and slight swelling of both submaxillary glands } rumbling in bowels (lo m. after dose). 9th d., shooting pains in head, (parietal region), contmuing all d., but not so bad p.m., generally lasting only a few m. ; pains ofsame character in mastoid process j dryness of throat on rising in m.; pains in hypochondria, continuing all d., not so bad pun. ; at 9 a.m. boring pain in or near umbilicus, lasting 15m.; about ^ h. after breakfast uneasiness of bowels, as if diarrhoea would come on. i oth d., still nasal discharge, less profuse, but of greater conustence ; paint in head at different times during d., — still felt, but at longer interrals and with diminished intensity, on z ith d. ; eruption drying up. 12th d., a new eruption broke out about hips and thighs, of papulx, isolated, hard, white and flattened, some having^ a small red point in centre ; they itch slightly on first appearing, on scratching itching becomes more violent, and burning supervenes, also deep redness of part, lasting 5 m.; in several h, they are more elevated and acuminated, and finally, in about 04 h., disappear gradually, others springing up ; several come also on wrist and between fingere. S4th d., z h. after dose, shooting pains in r. parietal region (recurring at 3 h.), and slight orgasm of blood to chest ; after 3 h. dull pains in occiput, soon passing OR J sticking pain in r. hypochtrndrium, boring pain in 1. intercostal spaces, and twitching of muscles of arms and legs ; after 4 h. rumbling in hypogastrium and pain in region of t ilium ; after 5 h. pains in head continue at irregular intervals ; pains also in r. abdominal muscles, soon passing off. 15th d., in m. on arising dryness and huskiness of throat, lasting about an h. ; p.m., while walking in open air, sense of heat in praecordia, with fulness in abdomen, going off soon after sitting down. z6th d., urine of deep orange colour, secretion txing somewhat increased. At 4 p.m. felt dull and stupid, with inclination to stretch and yawn frequently, oppression of chest, aversion to mental or physical exercise ^though walking in open air relieved) j sensarion across bridge or nose as if nasatl bones were being pressed together or inward, sharp cutting or pungent pain at lower end of rectum, pain in muscles of neck and shoulders, and violent beating of heart for 5 m. on ascending stairs. 17th d., pains in head; sometimes sharp cutting pain in throat, in rectum, and in lumbar region j stilt increased urine ; skin of whole body sensitive, leaving burning sensation when scratched, i8th d., occauonal shooting pains in r. parietal region ; several times sharp momentary pains in throat, 1 9th d., occasional dull stupefying pains deep in orbits ; sometimes excessive itching of skin. {Ibid.)

1. John Fox, act. 30, took ist dil. n. and m. for 4 d. ist n., restless sleep, with anxious incongruous dreams } woke up shedding tears, having dreamed of hearing of death of a brother, and could not get over emotion for some h. 1st d., mind somewhat confused, dull feeling in head j on waking in m. abdomen distended, followed by abundant and loud flatus, continuing 14 h. and d., muddled and confused feeling in head, with inability to think, lastmg all d., worse in e. ; in m. tingling with unpleasant itching in orifice of urethra, coming on suddenly and lasting a few m. N. again r^ess, with anxious and unpleasant dreams, unremembered in m. 3rd d., impatient and restless mood, with stupid feeling as before in brain, very irritable and morose temper, worse in e. ; itching as before in urethral orifice, e. ; at n. involuntary seminal emisuon, which has not occurred for many years. 4th d., disposition same, also state of brain ; slight transient pains in 1. hypochondrium. At n. impossible and incoherent dreams. 5th d., same state of brain, with inactive mind j shifting pains, dull in arms, boring in hands, for several h., disappearing on getting up and moving about. Same kind of n. 6tb d., dull pains over frontal region and eyes; pain in F. hypochondrium ; increased flow of pale urine, forenoon ; soreness and stiffness along 1. stemo-mastoid } sudden transient boring pains on lying down at n., shifting ftom wrist and hand to ankle and foot for x h. in rapid succession, sometimes extending

along arm to shoulder, more frequent and painful on 1. side, — at same time or aJrernatively similar pains in temples. 7th d., on waking in m. unpleasant constricdrc sensation in pharynx, soon pa^^Ung offj pain in both orbits, worse on pressure nausea, with rumbling in abdomen, e. ; while sitting, ^ud^len darting pain up urethra and sharp pleuritic pains under 1. Ktemum, relieved by exercise ; contractive pain ia 1. ^J. lendo Achillis, relieved by motion. 8th d., dull stupefying pain in whole head,^^^ relieved by motion and aggravated by study; pain in forehead over eyes, v**ith tender- ^1 nesjt on pressure ; dull boring pain in small spot on 1. temple ; pulsating pain in 1. ear ; no stool for 3 d. ; sharp stitches or catches in lower I. lung on deep inspintion, e. in bed ^ transient shifting pains on r. side, from wrist up into body, then down through trunk to fool, relieved by motion j pulse stmng, full, intermittent, 70— lo Kcutnbcnt, 95 — 100 erect. 9th d,, aching in I. frontal protubenncc, frequent but transitory, with tenderness on pressure j freouent eructations of wind ^this continued 3 weeks); griping in upper abdomen, witii frontal htadache; faint and trrmuloas feeling, especially on leabt exertion. loth d., vcr>' irritable and easily vexed, with excitement of nervous system; boring pain in 1. frontal eminence ; shooting pain tn I, ear, lasting several m. ; nausea, ivith faint and tremulous feeling; rumbling and griping in bowels, with abundant flatus; sudden arthritic pain in knuckle-joint of I , then of r., ring finger ; drawing pain in posterior muscles o( r. thigh, with tenUern on pressure} boring pain in r, knee} dull pain in I. ankle, relieved by motion; tearmg pain in r. ankle, coming on while walking; transient rheumatic pain in dorsum of 1. big toe, shifting to 1. ankle ; impossible to keep quiet a m. in any one position, lower extremities especially fidgety, they become numb, tremulous, tad painful when quiet, and are relieved by shifrmg about, xith d., restless dispo>itiao and dull feeling over sinciput; meditative mood or internal reverie, inability to associatc mind with any external object, with feeling ot great prostration j transient boring

fiains in r. frontal eminence and in small spot in I. trmpie ; rumbling in bowrl^ foianed by griping pains, in m. ; feeling of great oppression in chest, with hurried breathing and prostration } on talking or reading aloud was obliged to stop wenl times in a sentence to take breath — all c. ; puUc So, strong and hill, while recumbent, 1 10 when erect ; transient pain in 1. shoulder and in extensor muMrlcs of r. lower arm ; chilly sensation in e., with cold feet, izth d., disposition, ic, as before ; dull pain over eyes, relieved by movement ; dull stupefying pain in sinciput, finally extending to both sides of occiput ; dull boring pain in occiput ; dull pain in r. orbtC, as if bruised, worse on pressure } griping in bowels, with nausea almost tu vomiting, for 4 h. in e. { tenderness to pressure over renal region ; sudden darting, stinging pains running up urethra w'hilst sittings frequent micturition of colourless urine; sharp pleuritic pains in I. chest while sitting, lasting a few m. j soreness and stiffness of r. stemo-roastoid, worse on moving head to affected side, and vice 'versa (continued II d. more); tenderness on pressure along whole spinal column; great weakness across small of back, extending round trunk, as if body was broken. 13th d., pain in bowels ; great weakness and oppression of chest, with shortness of breath, followed by nausea even to vomiting ; exce!ksivr and continued yawning fi>r an li. aher guing to bed ; restless sleep, with much grinding of teeth (this symptom occurred frequently during proving), and every variety of fanciful dreams. 14th d., great nervous excitability and trembling of whole body, with pulse at lao (previously too, intermittent, irregular, and almost imperceptible) ; panting breathing on least exertion, particularly on ascending stairs, with violent palpitation ; frequent involuntary deep breathing; mind contused, and entirely unable to listen lo lectures, feeling of great prostration and utter inability to think, attempt to exercise mind increased depression and brought on hurried breathing and great anxiety; at noon was obliged to leave college and lie down; at n. highe-tt degree of restlessness; vivid, sometimes congruous, sometimes incoherent and disgusting dreams in rapid succession. From 15th to am d. found it too diiHcult to take notes, mind being so conftised and inactive. State was as from iilh tu i4.th d., if an}lhing growing worse as to nervous symptoms. On aist n. highest degree nf excitability, with fever, opprenston of chest, and anxietas till 1 ajn., when he fell asleep, but woke frequently from most vivid, horrible, and frightful dreams; on rising next m. passed a very large quantity of very dark red urine, of very strong odour ; during d. urine gradually diminished in quantity and colour, and he felt in every respect better. 30th d., mind was still confused, making study for any length of time impossible ; temporal arteries much distended, as oUo superficial

vessels of frontal region (a symptom somewhat present during whole proving) j pulse now 80. (Ibid.)

1. S. Warren took i dose of 5 dr. of md dil. Dull pain in r. side of head, rather on r. parietal protuberance and frontal eminence ; sense of hearing more acute, noise is painful ; tongue slightly coated, whitish ; food tasteless, sense of scraping in throat on swallowing, m., and as if some foreign body was in throat ; sense of dryness in fauces and continued desire to swallow j not much appetite ; sleeplessness at n. {IbU)

2. a. J. B. Wood took repeated doses of i, dil. for 7 d. 3rd d., itching of scalp, with slight eruption on forehead, which soon disappeared; at n. rest much disturbed, horrid dreams, pain in bowels, copious urination. 4th d., dull feeling and slight aching in head ; looseness of bowels, 5th d., soreness of teeth j bowels still loose; copious urination. 6th d., bowels same; slight headache: sense of weight in arms ; drowsiness in day time, sleeplessness at n. 7th d., rumbling sensation in bowels, with slight pain. There was some recurrence of the symptoms between 17th and 19th d.

b. Took ist dil. every 48 h. (how often not specified). Loose stools, but with straining, and only passed with much effort. This symptom remains after 3 weeks ; largely mcreased secretion of urine for 24 h., quantity was enormous; through ist n. restless tossing about, no sleep till towards m. ; same thing on 7th n. (Ibid.)

1. Dr. F. Bishop took repeated doses of md dil. for 1 d. Became restless and unable to sleep on ist n. about 3 to 4 a.m. (very unusual), and d., languid and uneasy throughout ; dreamed all n. ; excessive itching of scalp for i h. 3rd d., eyes looked very red and inflamed ; aversion to study or thought ; teeth of 1. side felt elongated and sore ; violent pains in upper molars (sound teeth), boring and digging, with profuse flow of saliva, worse on walking in cold air and from contact, also from heat of high degree, partial ease from lying down in cool room, — took mercurius 30 with relief; dryness and soreness of throat and mouth, and of mucous membrane of nose ; no stool (very unusual) ; urine free ; great restlessness and inquietude ; fugitive pains through 1. side ; very restless at n. (as also on and and 4th) ; frightful dreams, as of deaths, much affected by them. 4th d., loose stool ; enimbling in teeth of I. side before breakfast, and violent pain after eating ; urine free and pale; same dreams. 5th, n., entire sleeplessness after 4 a.m. 6th d., itching of scalp (this more or less every d.); soreness and pain in throat; copious urination. A month after, profuse secretion in throat, with constant hawking ; urine very profuse, pale, and depositing a white sediment ; restless at n. after 4 a.m.

2. a. Warren Freeman took md dil. twice daily for a weeks. First symptom he noticed was constant dreaming at n., after going to bed ; dreams were of ordmary occurrences of d., sometimes mixed with the fantastic. Also dull oppressive feeling through forehead, with sometimes dull pain extending across from temporal bones, apparently at base of brain ; had loose stool every d., sometimes twice a d., with some pain in rectum, and slight colic before stool.

b. He now took repeated doses of 8 dr. of a 4 dil. for 3 d. On 5th d., on rising in m., and lasting throughout d., constant eructation, tasting, a.m., of sulphur, p.m., of carbonic acid gas; after supper flatus passed into intestines, causing boring pain, and smelling of sulphuretted hydrogen when emitted. About 10 p.m. a very watery stool, and again at i a.m. and about daylight, with much flatus. On 7th and 8th d. similar operations of bowels, and on former, slight toothache on rising in a decayed tooth, mcreasing till noon, when it was severe, cheek considerably swollen, and saliva running freelv from mouth, neighbouring (sound) teeth felt elongated ; after dinner, dull, painful, stupid feeling in head, with considerable fever ; pulse 88 ; toothache subsided towards n., but he nad a similar attack next d., and cheek remained swollen up to loth d.

c. He last took 4 dr. of same dil. twice daily (for how long is not stated). Whilst doing so had for a d. acute pain in r. hypochondrium, especially on laughing or movement, when pain would be of a darting-sticking kind. Afterwards he had a peculiar indescribable sensation at cardiac orifice of stomach, especially after eating a nearty meal,— a coolish painfiil sensation, as if parts were over.distended ; it lasted about a week. {JbitC)

1. Mortimer Slocvm took repeated doses of ist dil. for 5 d., and on 9th,

loth, and nth d. 3rd d., 5 h. after ist dose, slight headache, heavy sensation In head, and inclination to drowse. 4th d., pain in aodomen, worse on itooping, in e., continuing, with distension of abdomen, nearly ail next d., and recurring, with flatulency, on 6th e., when also he had saltish expectoration. 7th d., icabUity to think, with restlessness at n. ; dry parched throat all d,, with sense of scraping; pains in 1. hypochondrium at 6 p.m. ; frequent dreams of gloomy character, rousing from sleep. 9th d., heavy frontal headactie. loth d., dry parched throat in e,, a draught of air irritates and produces cough. About middle of izth d. return of I. hypochondriac pain. {Ibid.)

1. a. T. C. Bunting took repeated doses of i, dil. for 4. d. and d., stitch in heart, alter dinner. 4th d., soon after ist dose, dull presuvc pain on both sides of abdomen, about Poupart's ligament. 3 h. after, partial prolapse of rectum during stool. 5th d., heaviness as from a stone in stomach, with some pain and tenderness: flatulence } has been restless for some nights, dreaming much, and waking uj^— all contrary to habit.

b. Took same, a dose on ist, 3rd, and 6th d. After going to bed zst d., sharp pun for some moments over r. eye, extending to temple ; before falling asleep a kind of tingling in front and upper jaw, and sensitive feehng in teeth. 3rd d., pain in exposed nerve of a front tooth for a short time only ; on rising, hoar^ness, as if from dryneu in larynx, it went off after breakfast. 4th d., bruised pain in 1. eye, especially on light pressure, for an h. ; still hoarseness, whose continuance next d. led him to take no more of the drug. 7th d., sore and loose sensation in front incisors, as if chilled hf cold air (is not subject to pain in teeth) ; feeling as if diarrhoea would set in ; blood passed during stool.

c. Took two doses of xnA dil. Pain in r. iliac region, as if a stone were in inguinal canal. {Ibid.)

1. W. A. Leavanway took repeated doses of i. for 4 d. 4th d., dull «:bing

Eain in 1. shoulder, not continuous ; also in r. shoulder, alternating with same in r. ip, passing down the limbs. 7th d., frequent empty eructations; dull aching pain over sacrum, a little below its union with the lumbar vertebrx, worse during motioo or standing. 8th d., same pain in 1. knee, at upper outer angle of patella, extending beneath it ; dull darting pam in r. side, from within out. 9th d., intermittent, puL sating, aching pain on vertex, in small spot beneath scalp ; umilar dull subcutaneoB aching near 1. side of sternum, a little below centre, worse from pressure and while sitting, passing off on movement. i8th d., sharp cutting in urethra, e., from within outward ; sharp darting pain in upper and outer part of r. orbit, and same at end of I. great toe. 19th d., scraping tickling sensation low down in bronchiae. aand d., sharp darting several times during d. in 1., then in r. side. 14th d., itching over body, rubbing felt grateful but did not relieve, rather adding a burning sensation. a7th d., e., sharp pain in 1. side, sometimes extending to r. shoulder, then to r. ude, then spreading over upper part of back, — continuing a long time ; frequent chillr sensation, also for a long time. All symptoms are worse while sitting, and pass off on movement. {Ibid)