Chamomilla
作者:Richard Hughes & Jabez P. Dake — A Cyclopaedia of Drug Pathogenesy
Volume II — Main text
CHAMOMILLA . *
Matricaria Chamomilla, L. Wild chamomile. Nat. Ord., Compositæ. I. Provings.-I . HAHNEMANN, Fragmenta de Viribus. Contains 272 symptoms from self and 3 from authors. 2. IBID. , Mat. Med. Pura, vol. iii of original, vol. i of translation . Contains 461 symptoms from self, and 30 from Stapf (See ii, 1 ) . 3. a. Five persons took extract in doses of 2-24 gr. daily. Although but slight effects were produced, the following symptoms were observed during its use, though they did not occur in all : bitter aromatic taste, eructations, oppression of stomach, nausea, disgust, inclination to vomit, pinching in abdomen, diminished appetite and evacuations, flatulence, yawning, hiccup, furred tongue, rapid pulse, palpitation, increased heat, thirst, confusion of and rush of blood to head,headache, weariness, excited irritable temper and restless sleep. ( Zeitsch. d. k. k. Gesell. d. Aerzte zu Wien, Dec., 1844.) b. SCHNELLER, one of the above, gives following details. While taking 8-14 gr., besides the disgusting taste, he had-soon after ingestion-slight palpitation ; in e. flying stitches in r. chest, near 5th rib, anteriorly, lasting a short time and increased by deep inspiration ; besides these on taking 12 gr. he had slight stitches in cardiac region, appetite lessened, head warm and confused. During doses of 16-20 gr. these pains declined, and symptoms ofderanged digestion ensued, viz. oppression of stomach, discharge of wind upwards and downwards, yellow furred tongue, diminished appetite, increased rapidity of pulse and temperature of body, and gloomy irritable disposition. After two last doses, of 22 and 24 gr. respectively, stitches in cardiac region again appeared, but were not confined to this part ; pain extended-at one time of shooting, at another of drawing character, now r., now l.-down * See also Anthemis nobilis .
legs to dorsum of foot and ankle, then back to r. shoulder or hip, or 1 . side of head. Derangement of digestion increased, disgust at food ensued, costiveness, palpitation, quick pulse, and peevish disposition . These symptoms continued for some d. after leaving off medicine. (Ibid., 1846, ii, 404. ) 4. Dr. HENCKE took Ist d., 8 a.m., 6 dr. tinct., 2nd d., 12 dr. , 3rd d., 18 dr. In forenoon some drawing pains in shoulder-joints and ankles, with uncommon tired and heavy feeling in limbs, but especially painful weak feeling and restlessness in arms, as after over-exertion, e. g. fencing ; worse when at rest, going off when moving, walking in open air. Could not sleep before 2 a.m., partly on account of tired feeling in limbs, partly from hot and restless feeling, causing him to toss about in bed ; tongue dry, thirst. 4th d., on rising in m. qualmish feeling in epigastrium, causing a kind of anxiety and restlessness, and making him cross and indisposed for mental work. 7th d., 8 a.m., 18 dr. 8th d., 24 dr. Recurrence ofthe painful heaviness and tired feeling in limbs, lower extremities so tired and heavy he was unwilling to walk. When at rest tearing pain in ankles. Towards dinner-time painful tearing-burning in back of mouth, voice rough and hoarse, must sneeze several times, and had to hawk on account of viscid mucus in fauces. Some heat and restlessness at n. 12th d., 24 dr. 13th d., 30 dr. In forenoon, return of heavy feeling in all limbs, also wandering tearing pains in r. upper arm, 1. leg, back, temporal muscles, lastly in 1. teeth . E., pain in teeth much increased by taking tea, and it was so persistent as to keep him awake at n.; restlessness, heat in face. Spoke, groaned and tossed about in sleep. 14th d., m. before rising gradually increasing pain in bowels, making him twist about. Lying doubled up relieves for a short time. On rubbing belly flatus discharged with relief. After pains had lasted 1 h. rumbling in bowels, with pains and hurried call to stool, when, along with noisy discharge of flatus, loose fæces came away, but the pain in bowels was so violent that he felt faint and perspired all over, especially in face ; the bowel pain gradually subsided. During d. now and again tearing pains, also occasional griping in bowels ; tongue covered with a slimy fur. In afternoon a diarrheic stool, with slight griping and discharge of flatus. E., sudden repeated sneezing, creeping in nose, followed by fluent coryza, watery mucus dropped from nose at short intervals, this went off after three h. On going to bed, 11 p.m., disagreeable cold feeling. Woke at n. from prickling numb feeling in r. arm, which soon went off. 15th and 16th d., constipation, crossness, easily put in a passion. 17th d., well. (HENCKE, A. h. Z., lxvii, 89. ) 5. C. H-, student, æt. 23, rather dyspeptic, otherwise healthy. a.-May 17th. Took C. 12th dec., I gr. (probably ofthe trituration) . In 5 m. sudden feeling of exhaustion in limbs, dull pressure on upper part of head, extending to temples and occiput as if head were compressed from all sides, repeated feeling ofheat rising up to cheeks, feeling of oppression and slight constriction in larynx. Spirits depressed. The rest of the d. spirits composed and increased secretion of clear, acid urine. Uneasy dreams at n. with anxiety and oppression. When undressing itching in various parts of the body without eruption.- 18th .
On waking, weight in head and bruised pains in back ; I gr. C. 12 . Very severe pressure in upper part of brain, spreading as compression all over skull, the exhausted feeling of limbs repeated. These symptoms very transient. Felt better than usual, stool better than ordinary, urine again increased. Afternoon, slight confusion of head with transient painful pressure on eyes ; repeated stitches and transient spasmodic feeling in tragus of r. ear, sometimes extending into meatus. Itching when undressing as before.-19th. In m. 1 gr. C. 6. Pulse and breathing at first slightly quickened, but became slower after 15 m . In h. the pressure on top of head, spreading over whole head, especially in r. temple, returned. Towards noon congestion to head with severe pressive pain over r. eye, a feeling of pressure on that eyeball and very severe painful pulsation of temporal arteries with severe compressive pain in r. temple. The frontal pains that came on in m. lasted till e., pressing and rather severe, with pressure on both eyes and obtuse stitches in r. temple. Pulse quicker towards e. Thirst increased. When perspiring severe itching on perspiring spots ; many small, red pimples on back. Perspired easily, perspiration sour. Sleep restless, woke frequently. -20th. 1 gr. C. 6. Soon pressive headache, pressure in eyeballs, and feeling of a sharp point pressed in on r. side of head and r. temple. In forenoon, transient dull stitches in r. side of chest, also rheumatic pains in muscles of nape. Pressure and feeling of a weight in alveoli of upper jaw, especially on r. side, the teeth feel filled with lead. Head heavy, spirits low, short attacks of exhaustion in lower extremities. In afternoon the pressure in head returned. These attacks lasted each about an hour ; they consisted of a pressure on top of head that extended around, commenced slightly, increased gradually in intensity and declined as gradually, but did not go off entirely but continued more or less severe ; the seat of the pressive pains seemed to be chiefly the forehead and r. temple ; sometimes both,sometimes onlyone, were affected, and often there was an accompanying pressure on eyeballs in region of oblique muscle, but this was transient. Slight constriction deep in pharynx, especially m. and noon. In afternoon, oppression and stitches in r. side of chest (a common symptom with the prover), especially on breathing deeply, also pressive pain and blown-out feeling in alveoli of 2nd and 3rd molars in both sides of upperjaw ; this sensation extended with remissions to the zygoma, worse on r. side. Pulse slightly irregular, 75. Difficulty of falling asleep owing to numerous disagreeable thoughts. Frequent waking, and every time he was bathed in perspiration.- 21st . On waking, weight in limbs and attack of exhaustion ; also drawing and pressive pain in stomach and feeling of weight there as if stomach were stretched over a hard body. Mouth coated with rust-coloured mucus, tongue white, urine dark and acid, pulse full, 69. The pressive headache continued all d., also the asunderpressing and aching in alveoli of molars, also the pressure on eyes. Pulse 75 after eating and rather irregular. In afternoon tickling in trachea, frequent irritation tocough and constrictive feeling in pharynx. Frequent pressure in region of cardiac orifice of stomach, sometimes extending up the œsophagus, eructation of burning salt fluid, abdomen distended, sometimes cutting in it extending down to bladder, relieved
by discharge of flatus and friction. Difficulty of going to sleep and profuse sweat during sleep.- 22nd. On waking, transient cutting in abdomen deep down into pelvis, pressure and spasmodic contraction in stomach, oppressed feeling in chest, pressure on top of head, pressing in forehead and temples, and feeling of pressure ofa broad band on forehead and as if temples were pressed inwith fingers,head confused, especially when lying. During forenoon the toothache before described, lasting all d., great ebullition of blood to head and heat of face, oppression of chest and frequent stitches in chest. Pulse after dinner 79. During afternoon pressive and stupefying headache occurring periodically. Above navel a feeling of distension and transient nausea. Spirits rather low. Profuse sweat during sleep, which ceased when he awoke.- 23rd. On awaking, headache, especially in forehead, aggravated by movement and thinking or reading, with inability to fix attention. Buccal mucus bloody, urine dark coloured and acid. Pressure in alveoli of 2nd and 3rd upper molars and continued pressure under and in eyes. All afternoon, headache and toothache as before, tensive feeling in stomach and umbilical region. Pulse at n. 80. Long in going to sleep on account of disagreeable thoughts. Next 2 d. the symptoms gradually subsided. b.-26th. Took 1 gr. C. 3. Soon stoppage of nose lasting h. and feeling as if it would bleed. Slight pressive pain on top of head spreading to r. forehead and temple. Then tension in stomach and œsophagus with attacks of great nausea, with greasy taste and inclination to vomit ; these symptoms transient. Then attack of feeling of debility all over body, disinclination to mental work, laziness and prostration. All forenoon pressing pains in both temples, with feeling as if pressed by thumbs, toothache as before. These symptoms continued more or less all afternoon.-27th. Repeated the dose of 3rd dil. Soon the pressive headache recurred, also the dry and stopped-up feeling of nose and a slight attack of nausea with tensive pain in stomach and the toothache. Great itching of skin on undressing at night and a slight attack ofthe spasmodic constriction of œsophagus . -From 28th May to 3rd June, the above symptoms occurred occa- -3rd June. Took I gr. C. 2. The sionally, but in slighter degree. pulse soon rose from 64 to 100, and the respirations from 14 to 17 . Immediately the usual headache appeared, combined with heat of face and head. At noon the pulse was down to 84. During afternoon he had confusion of head with aching and pressing, in fits, heat of head, feeling of exhaustion frequently, the toothache as before, stitches from tongue to meatus auditorius, feeling as if the teeth of both jaws were full of lead. After supper increased flow of saliva with peculiar sweetish metallic taste, the saliva somewhat acid, swelling of the gums at Ist and 2nd r. upper molars with pain like needle pricks (rather a common occurrence with him),greatdislike tomental work, constant congestive headache on top of head, forehead and temples, increased by any mental operation. Pricking itching of skin on undressing.-4th. Woke from a disturbed dreamful sleep with confused head and the usual headache. Took I gr. C. 2. The headache soon increased, and he had severe pressing in orbital region with feeling as if eyeballs were compressed
from all sides with momentary dimness of vision. The swelling on the gums was the seat of tensive, shooting and throbbing pain, and there was painful pressure in the alveoli of all the teeth, especially those of the lower jaw towards the r. angle. Spasmodic tension in stomach and around navel, abdomen somewhat distended. The tension of the stomach extended up the œsophagus into pharynx and was attended with anxiety, nausea, increased secretion of sweetish saliva, warm feeling of head and flushing of face and head, tension in velum pendulum palati and spasmodic contraction there. The headache increased much h. after taking the dose and this increase lasted 2 h. When lying feeling of dislocation in both soles and cramp-like contraction in them. This recurred several times during d. Frequent deep stitches above heart, worst in m. Pains in sacrum with bruised feeling and transient stitches after sitting leaning forwards. The headache and salivation much increased e.; a stool, the first for 48 h. Spirits much depressed, feet cold.-5th. After restless, dreamful sleep woke with much the same symptoms. The mouth was coated with bitter slime of feebly acid reaction. Headache, pain in stomach, nausea and flow of metallic, sweetish saliva, drawing and stretching in joints of lower extremities, especially knees, with great feeling of weakness in them, and the previous pain in soles. At 8 a.m. bruised pain in lumbar and dorsal muscles, stretching of whole body, bruised and shooting pain in ulna and tibia. The parulis diminished in size. All forenoon yawning and desire to stretch, great prostration, inability to think, just like the commencement of a serious illness. At II a.m. severe stitches through r. chest, cold feeling in abdomen, especially renal region, spreading thence over whole back and lasting long between scapulæ, along with this severe stitches in r. frontal protuberance, in rapid succession or many all at once, this repeatedly. Frequent shivering all over body and limbs, increased secretion of urine ; after h. feeling of warmth all over followed by gentle perspiration. Head and all symptoms relieved by 2 p.m. At 3 p.m. took I gr. C. I. In h. the old headache returned with flushes of heat all over head and face, weakness of limbs and joints, dull stitches in occiput with desire to bend head backwards, bruised feeling between scapulæ and intercostal muscles, especially when bending forwards, flow of metallic, sweetish saliva, nausea, head confused, pain in 1. peronæus muscle as after going up hill, also pain in extensor muscles of l . foot, and thence upwards to middle of thigh, stitches in l. metatarsal bones, foot goes to sleep, sensation of a band tightly constricting leg above ankle, hot feeling in l. foot with outbreak of sweat, crawling in nose and lachrymation.-6th. After rising head free, but later the headache and some of yesterday's symptoms recurred. At 10 a.m. crawling in r. nostril as if about to have coryza, and lachrymation of r. eye. Parulis gone. At 2 p.m. took same dose. Similar symptoms appeared and, in addition, stitches in r. maxillary joint, shooting in cartilage of 6th rib, roaring in ears, heat of head and face, weight of head, tension and pressure in pharynx and uvula ; cramplike sensation in flexors of forearm with feeling of gone-to-sleep of it, stitches along metacarpal bone of 1. thumb, feeling of prostration, stitches in cartilage of 6th rib, aguish feelings like yesterday, pulse
full and hard, 80, respirations 18, heartburn.-7th to 11th. Some of the same symptoms, but in even slighter degree. c. 12th. Took on waking I dr. C. 4. Soon a return ofsome ofthe old symptoms and, in addition, dull stitches in different parts of the body, especially deep injoints with lamed feelingof thesejoints, frequent strong erections followed by general heat, then sweat with relief of all the other symptoms except nausea. 7 a.m., pulse 98, small and soft, stitches above heart, desire to bend head backwards, dull stitches in mastoid process, stupefied sensation and feeling ofcompression of brain. 9 a.m. , swelling and pain in abdomen as if diarrhea were coming on ; relieved by discharge of flatus smelling of sulphuretted hydrogen. 1 p.m., severe stitches in r. temple, return of headache aggravated by sitting and studying, relieved by walking. 3 p.m., stitches in a small place above 1. nipple for some m., repetition of the stitches in different parts of the body, those in arms and legs attended by paralytic- like pains, with feeling of having over-exerted them. Coldness in renal region with frequent attacks of rigor, increased urine, drawing pains in fibula, prickling in various parts of body relieved by scratching. Constriction of chest at level of nipples, pressure in r. side of forehead and r. temple, and sometimes some obtuse stitches there extending to occiput. The pains made him very cross ; he described them always as unbearable.- 13th. Took 2 dr. of $. Similar symptoms occurred, also wandering pains in limbs. As a rule the pains come on when sitting or lying, and are relieved by walking about. At noon a feeling in œsophagus as if a ball filled with air were forced by the contraction of the œsophagus up into pharynx ; this was three times repeated.-14th. Took 3 dr. of 4. Soon a flush of dry heat over head and trunk,jerking stitches like electric sparks from 1. shoulder to nape, the usual pains in joints of elbow, wrist, and knee, and thence through bones, great prostration. Aguish fits, as before, about 8 a.m.-15th. Nothing particular except stitches in knees and ankles, constriction in pharynx, and toothache, slight digging in molars, transient but intolerable.-16th. Took 4 dr. of 4. Many of the symptoms of former days occurred.-17th. Nothing particular save feeling as if tonsils were swollen and uvula too long.-18th, 2 p.m., 5 dr. of $. From this time forth during the remainder of the proving, the symptoms previously noticed recurred without much variation. We shall therefore only give the unusual ones that occurred on different days, but it must be remembered that besides these many of the previously-observed symptoms cropped up. The teeth felt heavy as if filled with lead, boring and digging in the roots of some molars relieved momentarily by cold water but instantly recurring, sharp stitches in r. meatus auditorius, feeling of fulness of nose and as if it were stopped up. d. 19th. At 7 a.m. drawing in joints, springing from one joint to another. Took at 7 p.m. 5 dr. of 4. Soon feeling in r. forearm as if it were too short, and on bending back hand pain especially under the styloid process of radius, warmth and full feeling in epigastrium, knees bend readily under him when walking, weight and numb feeling in calf-muscles when sitting, feeling as if legs were tied tightly round with a broad band with great weight in them. After
h. pressure in trachea with irritation to cough.-20th to 22nd. No med.- 20th. Constriction in larynx causing cough with mucous expectoration.-21st, at 6 a.m., epistaxis from r. nostril.-22nd. Irritation oflarynx and coughing up of a few drops of blood. At 9 a.m. throbbing and hot feeling in alveoli and gums of upper molars, later in lower molars, boring and digging in roots of teeth with momentary relief from cold water.-23rd. Took at 5 p.m. 10 dr. of 4. After 15 m. difficulty of swallowing as if tonsils were swollen. After 45 m. heat and burning in stomach, anxiety, restlessness, itching in prepuce and glans. After 50 m. bruised pain in anterior aspect of thighs.- 24th. At 8 a.m. feeling of pushing out and weight in roots of upper molars . At 2 p.m. took 20 dr. After 10 m. flush of heat over head and face, dull shooting and drawing along ulna and stitches in scalp, bruised pain in muscles of legs, stitches under head of r. fibula, along metatarsal bones, in muscl. bulbocavern. and r. inguinal region with feeling as if something were coming out there, feeling in arteries of forearm as if they were too short. After 4 h. feeling of rawness and scraping in larynx.-25th. On waking paralytic stitches from joints along hollow bones, worst when lying, better on rising. At II a.m. stitches in meatus auditorius, increased saliva with feeling of pressure in parotids. At 1 p.m. 40 dr. After 20 m. pressure above r. nipple. After 30 m. hot feeling in head and face, burning in face and roaring inears. At 3 p.m. stitches on inner side of patella, in the knees, and through head, jerking from hard palate perpendicularly through to scalp.-27th . Took at 6 a.m. 60 dr. Soon oppressed feeling in chest, constrictive feeling in pharynx with dull stitches in it to base of skull. At I p.m. constant bruised feeling in m. peron. and pain in heel as if after long standing and as if calcaneum would press through skin. After this no more of the drug was taken.- 28th, m., feeling of weakness and weariness in legs, bruised pain in bellies of flexor muscles of toes as from excessive walking, dull stitches in ankles, knees, and wrists, spreading to neighbouring long bones. -29th, 6 a.m., tearing in legs and arms, especially in fibula, tibia, metacarpus and metatarsus, and along outside of radius, pains in knee and elbow-joints in their flexor aspect, especially when these joints are stretched. At 4 p.m. stitches in tubera parietalia, pressing, aching and weight in head, especially along coronal suture, and pain in abdomen as if diarrhœa would come on, relieved by discharge of flatus. -July 3rd, 6 a.m., teeth very sensitive to touch . 10 a.m. , frequent shudderings over back, head confused with pressure in it.-6th. Recurrence oftearing pain in forearm. Some ofthe symptoms previously experienced recurred as late as the 15th July. (Prof. HOPPE's provings, Hom. Vierteljahrsch., xiii , 7.) 6. REIDHAAR, medical student, rather dyspeptic, tongue always white, subject to headaches and pains in stomach, but is on the whole in good health.-April 22nd. At bedtime C. 6, 1 dr.- 23rd. On rising urging to stool, rumbling in bowels, eructation, almost inclination to vomit. At bedtime same dose.-24th, 1 p.m., roaring in ears. At bedtime same dose.- 25th. Dry mouth, whity-yellow tongue. E., C. 3, 1 dr. 26th, 27th, and 28th same dose. No symptoms.-29th. C. 4, 1 dr.-30th. The accustomed gastric symptoms m., also some
headache ; soon after midday meal painful cutting above navel ; afternoon after sitting pain in lumbar region and some transient pain in middle of 1. sole, much flatus, burning head and red face ; e., headache. II p.m., pain in back, pain in soft palate, a kind of burning accompanied Ist. by some inclination to cough. At bedtime I dr.-May Nocturnal emission, tongue furred, lips dry, toothache in l. upper maxilla after every meal. 8 a.m., inclination to vomit. 10.30 a.m., some shooting in back. 11.15 a.m., painful pressure under r. clavicle, shooting in sacrum. I p.m. , a slight transient pain in l. temple followed by heat and pressure in forehead ; constant eructation, tired and weak in knees. At n. 1 dr.-2nd. Tongue very furred, constant eructation. 9.30 a.m., trembling of legs and hands, vertigo, discomfort in stomach, transient stitches in outer side of r. thigh close to natis, fatigue, burning in forehead, general headache, vertigo on rising from seat, transient stitches in r. parietal bone, and in back. At n. I dr.-3rd. Last n. cough with irritation deep in trachea.-4th. White tongue, much flatus and constant eructation, vertigo, sour eructation and repeated pressure in stomach, burning heat in forehead, trembling of hands, weariness, drowsiness.-5th and 6th. Some of previous symptoms.-7th, 6 a.m., 5 dr. Some transient pain in stomach, eructation, discharge of flatus, and slight pain in abdomen, lastly transient pain above 1. ear. Toothache whilst eating breakfast. After breakfast griping in bowels, flatus, and sour eructation. In afternoon some sacral pain,weariness of legs, profuse sweat on feet (to which he is subject), pain under 1. clavicle.- 8th. 10 dr. , eructation and nausea. Afternoon, shooting in back.- 9th. 15 dr., similar symptoms.-10th. 20 dr., eructation, shooting in r. scapula, r. side of head, 1. temple and abdomen, with urging to stool, discharge offlatus. Afternoon, transient pain inr.shoulder-joint, pain in l. side of fauces when swallowing or pressing under 1. angle of jaw, very hot hands, dorsal veins of hand much swollen, sweating on different parts of body.- 11th. On bending r. knee shooting in its anterior surface. At noon tickling in soft palate. I p.m., pain in r. knee returned, also shooting in volar aspect of second phalanx of r. thumb. E., jerking shooting about r. scapula, shooting in both knees, pain in soft palate and fauces. Very tired.-12th . On rising weary, headachy ; shooting in outer side of lower half of r. thigh on bending leg. Noon, transient shooting in anterior and superior half ofl. chest. 2 p.m., pricking under ensiform cartilage and transient shooting in r. scapula.-13th . Noon, transient shooting in l. elbow-joint, in both wrists, in r. side of head and in forehead ; shooting jerking in first joint of r. thumb, and pricking in r. side of chest near sternum. 6 p.m. , burning hot face and ears, pressure with tongue on 1. upper and lower canines and first 1. molar causes pain.-14th. 20 dr., soon pain in abdomen, and later transient shooting through and across belly ; after breakfast some pain in abdomen near both superior spinous processes of ilium, also some of previous symptoms.- 15th. Nocturnal emission ; m., shooting in outer side of r. knee, vertigo after stooping and cough. Afternoon, shooting in first joint of r. thumb, in 1. thigh, in back, jerking shooting in 1. occiput, shooting in 1. ankle-joint and r. knee, much flatus, gripes, and toothache.- 16th. 30 dr., shooting in r.
knee, in lower half of r. thigh, in r. side of belly, pain in hips, and toothache while eating.- 17th. Besides some of above symptoms tensive pain in r. thigh as after exertion.-18th. 40dr.; in addition to old symptoms, after dinner pain above pubes.-19th. 20 dr. (the last dose). No new symptoms, except that the feet became sore from walking.-29th. Shooting near scrob. cordis 1. side, pain in l. temple, shooting in ball of 1. hand and through middle of dorsal aspect of r. forearm.- 21st. Twitching in 1. pectoralis major, shooting at r. nipple, under r. axilla, in l. temple, in first joint of r. thumb, near r. side of sternum, and all through 1. leg; pain on r. of scrob. cordis.-22nd. Pain in stomach. Noon, pain in r. side of top of head. Afternoon, repeated shooting on outer side of 1. elbow between 1. index and thumb on the dorsal aspect, headache and vertigo after sitting long at mental work. Griping and shooting in belly all d. E., violent headache, pains in stomach, and general illness.-23rd. The symptoms from this time were trivial, mostly repetitions of previous symptoms, and undefined or shooting pains in different parts, as neck, nates, chest, back, arms, wrists, elbows, fingers, thighs, legs, feet, knees, ankles, such pains, in fact, as he was more or less subject to before proving the medicine. (Ibid, 388.) 7. I have proved the Ist dil. sufficiently to learn its action on the liver. On a healthy person its effect is to produce motions like those of a healthy baby ; it increases the secretion of healthy bile. (SHARP, Monthly Hom. Rev., xx, 746. ) 8. a. A man in good health took (April 28th) 5 dr. of tinct. at n. Inh. rumbling in stomach. Next m. less free evacuation than usual ; and this continued the same for 4 d. Afterwards, the colour darker than usual . b. Same, May 14th, took 10 dr. at n. Inh. rumbling at stomach. On 15th, m., stool as usual in quantity but rather darker. On 16th, no evacuation. On 17th, evacuation very small in quantity ; slight indigestion during d. 18th .-Everything as usual. (Ibid. ) II. Poisonings.-1 . A girl, æt. 19, drank some cupfuls of strong chamomile tea. At n. terrible feeling ofheat, with burning unquenchable thirst, dry tongue, stupefaction ; in m. in bed eyes halfopen, downward directed, pupils somewhat dilated ; drowsy and stupid, speaks unwillingly and curtly, in disjointed phrases ; on the (lightly) covered parts burning heat, while those uncovered are almost cold ; continual alternations of heat and cold in upper extremities, forehead cold while cheeks are hot ; profuse sweat on covered parts ; glittering before eyes, did not see where she was ; blacknesss before eyes ; giddiness when sitting upright, not when lying ; weight and stupid teeling in head ; short, noisy breathing ; going to sleep of 1. arm without having lain on it ; when sitting up or turning in bed, tearing pains in forehead, with sensation as if a lump fell forwards ; tension in knee, and up calves ; immediately on throwing off bedclothes violent shuddering ; general heat from 9-12 a.m., then profuse sweat. After 24 h ., she sits stiffly on a chair like a statue, and seems to take no notice of anything about her ; cannot be got to speak. In n. violent heat with sleeplessness from bruised feeling in limbs, of which she complains with
much ill-humour ; face hot and cheeks red ; draws short deep breath with great elevation of chest ; must draw up legs on account of pain in calves and knees, when outstretched they go to sleep ; red tongue ; she sways her head forwards and backwards and contracts her brows. (STAPF, in Hahnemann's Reine Arzneimittellehre, Ist ed., vol. iii. ) 2. A healthy, sensitive woman, offirm fibre, and halfway through her pregnancy, took 5 dr. ofvolatile oil of C. for cramp in calf. The dose was much too strong for her. First there was loss of consciousness, the cramp increased, then occurred transient convulsions in limbs, eyelids , &c. A kind of hysterical movement about navel, not unlike after-pains, but more annoying, lasted for several d. (HAHNEMANN, Lesser Writings, p. 314.) 3. A female infant who from the birth had been dosed with chamomile tea. Great swelling and bluish redness of eyelids, first of 1. then of r. eye, cannot open eyes. Conjunctiva of lids swollen and dark red. Inner surface of lids and eyeball covered with much yellow mucopus and bloody fluid. Pressing on eyelids causes blood and pus to exude between them. Discharge of pure blood several times during d. on crying or coughing. Dried matter in canthi and edges of lids. Conjunctiva scleroticæ inflamed. Discharge of dark blood from genitals for 8 d. (KNORRE, A. h. Z, vi, 34). 4. Two children plucked chamomile flowers and had vomiting of bile. (Ibid. , 35) . 5. In substance or strong infusion C. produces sense of warmth in the stomach, and, it is said, some acceleration of the pulse. In large doses it occasions nausea, vomiting, looseness of bowels, pain with fulness of head ; and it is even said (by Giacomini) in certain idiosyncrasies to produce a sort of somnolent intoxication with general depression and exhaustion. (STILLÉ.) III. Experiments on animals.-1 . By far the most important physiological effect of C. oil is its power to lessen the reflex excitability. Binz first drew attention to this property of C. among several other essential oils, and Grisar has since worked out the research with special care and very important results. His experiments were conducted on the principle introduced into practical physiology by Turck. This consists in suspending frogs with one limb immersed in dilute acid; the time which suffices so to irritate the limb as to cause it to be spasmodically withdrawn from the fluid is carefully marked by a metronome, and forms the test of the degree of reflex excitability. The element of volition is got rid of by the preliminary adoption of Goltz's process-the division of the cerebral hemisphere by a knife passed through the skull from one posterior orbital canthus to the other: this reduces the frog to the condition of a perfect machine for testing reflex excitability. Frogs so prepared are exposed to the acid, their degree of reflex excitability is tested by metronome beats, and the C. or other ethereal oil is injected beneath the skin, after which successive observations are taken as the system becomes more and more impregnated with the drug. The result of experiments made in this way, and also with decapitated frogs, leaves no doubt that C. oil, even in doses that are not fatally poisonous, reduces the reflex excitability of frogs in a very marked degree. But the most important fact evolved by the researches of Grisar was that reflex excitability which has been artificially excited by strychnia or brucia can be calmed again by C. oil; or rather, that an animal fortified with a dose of C. oil is not capable of being tetanised by a dose of strychnia which throws an unprotected frog of similar size into characteristic spasms . (PHILLIPS, op. cit.)