Chininum arsenicosum

Volume II — Main text

CHININUM ARSENICOSUM.

I. Provings.-1 . Dr. Muhr triturated for I h. 10 gr. Chin. ars . with 90 gr. milk and sugar. While triturating he carried on a conversation with a patient. Suddenly had a bitter metallic taste, but continued to triturate and made 2nd trit. E., very painful cutting in bowels, lasting & h. Sleep broken. Next m., 8 o'clock, the heart commenced to tremble, with a rumbling noise, and he could not distinguish the heart's beats. This lasted one h., then the heart's and pulse's beats (the latter could not be felt on 1. side) became irregular, and 200 per m. In solar plexus pressure (like that caused by indigestible food) felt towards the back as a squeezing ; touching the spine there caused pressive pain. Painful weariness of shoulder- and elbow-joints. Weakness of lower extremities. Slight pressive pain in forehead and temples. Noon, heart's beats more regular. Pulse could be felt in temples and r. radial artery, still 200. Pressure behind stomach, not removed by eating. Heart's beating felt when leaning the back against something. After I p.m. did not feel heart's beats, but felt a stoppage of the heart and very slight, rapid beating of temporal arteries. Pain in solar plexus gone ; less weakness ; breathing quite easy, as if thorax were hollow. After 2 p.m. recurrence of squeezing pain to spine. Palpitation again felt on leaning back ; pulse 200, regular. Took verat. 2 . After 4 p.m. pulse 88,head still confused. In 1. ear sensation and noise like that made by grasshoppers. Later all symptoms went off except sleepiness. (A. h. Ztg., lxxxviii, 39.)

Volume II — Appendix

Chininum arsenicosum.- After I. 1, insert the following : 2. Dr. TRITES took 15 gr. of 2, trit. at 8 p.m., Nov. 15th, 1882. In 15 m. peculiar pain at base of 1. chest, dull and with sense of pressure, as though caused by flatulence, quickly coming and going several times. At 8.30 took 10 gr. more, and repeated this dose at 8.40 and 9. At 10.45 sharp stitching pain at base ofr. chest in front, very persistent and worse during inspiration. 16th.-After good n., at 9.30 a.m. took 20 gr. 10.30, some aching pain 2 in. below umbilicus and I in. to r., seat couldbe covered with end of finger, transient, but recurring; position did not affect it. Also felt sore aching pain in 1st phalanx of l., and later of r. , thumb ; same also near 1. elbow and knee. 2.15, aching tired pain in 1. biceps, for some h. 2.20, took 30 gr. 2.45, aching along front of lower two thirds of 1. tibia; violent but transient aching in 1. great toe and little finger, and in region of 1. olecranon. 6, palms dry and hot, dull confused headache, pain is both frontal and occipital (in latter region at protuberance). Pains in extremities also continuing, suspended medicine. 17th. -Felt better, still had pains, but less severe. He continued to feel them, gradually growing less, for several d. 29th.-Feeling very well, at 2.25 p.m. took 30 gr. in water. At 3.15 pain as before at back ofr. thigh and in calf; also persistent severe aching in 1stjoint of 1. ring finger. 4, sore aching in 1. forearm, and in l. sole at root of little toe; dull aching in 1. chest 2 in. below and 1 in. to 1. ofnipple, unaffectedby breathing. These aching fleeting pains continued for a d., attended with feeling oftiredness,then gradually ceased. (Hahn. Monthly, May, 1888.) Additional provings made with hydrochlorate (Ch. muriaticum).* 25. B-, æt. 26, strong and healthy, on July 11th commenced to take Q. h. 0.005 grm. every m.- 11th. No symptoms observed.- 12th to 14th . Diarrheic stools 3 times a d. (probably caused by too new beer) . Diarrhea ceased on 14th.-16th. Towards noon slight pain in 1. temple till e.-19th. After a restless n.-waking out of confused dreams-feels poorly ; is exhausted, apathetic, listless. In m. has slight shooting pains in l. frontal and temporal regions, lasting till noon, but the weakness and prostration last all d.-20th. From this time he took daily oor grm. Q. h.-22nd. Sleep restless, disturbed by dreams. In m. headache recurs, especially severe over 1. supra-orbital border. Still bodily weakness, disinclination for mental work. No stool to-day. Urine not very copious, but frequent urging to pass it ; it is turbid and deposits a sediment.-23rd. Sleep again disturbed and not sound, but feels better. Headache is still present but slight. Stool normal.- 27th. No stool. In m. slight eructation, feeling of fulness in epigastrium, colický pains in * In the following provings the pulse and temperature were carefully noted; but as no appreciable changes were noted in them we have omitted the record.-EDS .

abdomen, flatulence all d.-28th . The disorder of digestive apparatus continues till a copious loose stool is passed at noon.-30th. Towards m., after restless sleep frequent waking with precordial anxiety ; he has the headache in l. temporal and supra-orbital regions. I h. after taking the dose palpitation of heart and excitement ; this lasts h., during which time he walks restlessly up and down in room . After this the previous prostration, weakness, and apathy come on and last all d.-31st. Sleep still disturbed by confused dreams. Headache returns but is slighter. Feels pretty well. Aug. Ist. No stool, feeling of fulness in epigastrium, empty eructations, flatulence all d. The headache in l. frontal and temporal regions recurs punctually in m., and for 1 h. there is along with it slight shooting pain behind 1. ear. This goes off, but headache persists. 4 p.m., heart's beats increased in quickness for h., with some anxiety and excitement. P. 96.-2nd. In m. headache and pain behind ear recur and last almost all d. Stool at noon, but without allaying the disagreeable full feeling in epigastrium and flatulence. Appetite poor.-3rd, 4th. The headache recurred both m., and lasted till noon.-5th. Feels well, hardly a trace of headache.-6th . Headache recurs more severely m., lasting till noon. No stool. M., eructations, flatulence, rumbling in belly, colicky pains. Bad appetite. Last dose of Q. taken this m.; in all 0.22 grm. Q. was taken. During next week he had slight 1. semilateral headache every m., lasting till noon, when it went off. On 7th a copious stool, after which digestion went on properly. (SCHULZ, Virchow's Archiv, 1887, cix, 25.) 26. C., æt. 26, subject to catarrhal affections.-July 11th commenced taking daily 0.005 grm. Q.-19th. Noticed nothing except a slight increase of appetite. He now took daily oor grm. Q. h.- 22nd. Restless n., many dreams. M., slight pains in region of r. supra-orbital border, going off in course of forenoon, but recurring in afternoon for a short time.-23rd. Slept better, but the pain in r. supra-orbital region came on in m., lasted a short time, and recurred frequently during d.- 28th. During last 4 d. the supra-orbital neuralgia did not recur ; to-day he felt poorly, sleep restless, frequent waking with anxiety from confused dreams. As a consequence felt in m. very weak and prostrated, frequent violent drawing pains in temporal and supra-orbital regions, increasing in intensity during d. and not going off entirely. Disinclination for mental work all d. Appetite not good. No stool.-29th. Slept better but still weak, apathetic . The pains in l. (?) half of head recur, but not so frequently as on previous d. No stool, pressive sensation in epigastrium, frequent empty eructations. Took at noon a spoonful of castor-oil, which caused a stool in afternoon, after which the stomach affection went off During d. appetite not very good. E., voracious hunger for sour things, which, however, he resisted, and it went off after 1 h.-30th . About I h. after rising there occurs for about h. singing and buzzing in ears ; after its cessation shooting pains in r. meatus lasting all d., as did also the supra-orbital pains, which came on in m.-31st. Feels better than the previous days. Headache almost completely gone, but still has the slight shooting pain in meatus. -Aug. 1. No stool,

rumbling in bowels, slight colickypains over whole abdomen, flatulence, appetite increased to voraciousness, frequent urging to urinate. Mere traces of the head pains.-2nd. Restless sleep, frequently disturbed, head pains more intense, eructations, pressure in stomach which does not go off after stool at noon, flatulence all d. Urine very scanty, although there is frequent urging to urinate. Slight and transient precordial anxiety and palpitation p.m. Appetite middling.-3rd. Though he has slept well is weak and prostrated. Appetite very bad, inclination to vomit. Urine as yesterday. No head pains.-4th . Feels better though still no appetite. No stool.-5th. The last dose was taken on 4th ; in all 0.205 grm. ( Ibid.) 27. J , æt . 22 , in good health. From his ninth to twentieth year had a tendency to epistaxis, but not since.-Nov. 26th. Began n. and m. 0.005 grm. Q. h . daily.-28th. No stool.-30th . In m. much flatulence, pappy stools, one m. after rising, the second after dinner. Feeling of fulness in stomach as though whole epigastrium were filled. After a walk p.m., about 8 p.m. extreme drowsiness combined with feeling ofweight in head.-Dec. Ist. Yesterday's symptoms continue. Flatulence but no stool m. Slight heaviness in sinciput, going off p.m. E. a pappy stool.-2nd. Stool only after dinner, not affecting feeling of fulness in stomach . 2 p.m. , weight in eyes, lids can only be raised by an effort. 4 p.m., conjunctivæ slightly injected, expression of eye dull.-3rd. With yesterday's symptoms (the stool after dinner is liquid) there comes on p.m. some palpitation, congestion of blood to head, face red and bloated, conjunctivæ injected, flickering before eyes. Slight epistaxis at 7 p.m., after which congestive symptoms were relieved .-5th . No stool on 4th, but one pappy stool after dinner on 5th. On both d. palpitation at 2 p.m., lasting 1 to 1th. Conjunctivæ injected and lids adherent in m. since 3rd, feeling as if eyeball were too big for orbit, feeling of sand in conjunctive. Both d. slight epistaxis . -6th. To yesterday's symptoms are added a marked increase of urine with constant urging to urinate. The palpitation lasted h. only.- 8th . Stool in m. Urging to urinate continues. Slight mucous discharge from urethra with strong erections. Better after a walk, but could not get rid ofsymptoms by mental work. After dinner, palpitation, heaviness in eyes, and feeling as if eyeball rubbed against orbital walls.-9th. Stool after rising, normal. Eyelids heavy, conjunctivæ injected. Urinary secretion increased, urging to urinate tiresome, inclination to erections, and mucous secretion from urethra. After dinner transient palpitation.- 10th. From to-day the dose was doubled. Urging to urinate continues. Normal stool, m.,after much flatulence. -T1th. M., on going upstairs epistaxis. Eyelids heavy, eyeballs feel too large for orbits . II a.m., pain comes on over orbits, gradually increasing, it has often a jerky character, goes off from r. side after a longish walk, but remains on 1. side till 6 p.m. At same time complete disinclination to work, numbness and fatigue in head. Severe palpitation after dinner.- 12th. Heaviness in head and eyes as yesterday, relieved by a walk. No med. taken to-day. Tendency to erections recurs.- 13th. Flatulence, constipation. The feeling in eyes continues. Last n. many uneasy dreams. Quantity of urine increased,

but urging and erections diminished . Orbital pains continue. In afternoon a liquid stool. Irritable and depressed,general malaise, better after a walk. Expression of face like that of a person given to excess in alcohol .- 14th- 16th. The symptoms of the 13th continue with equal intensity. The orbital pain is especially severe and jerking on stooping. Stupid feeling, disinclination for work, all somewhat relieved by a walk. On 15th after rising a peculiar numb feeling in both ears, as though he heard sounds through a curtain ; this lasted h. The climax of the action of the drug occurred on 16th. Awoke in m. with same symptoms of head and eyes, which increased by noon to an intolerable height. Inclination to vomit relieved after dinner. Humour irritable, face cædematous. In afternoon violent jerking pains in head only slightly relieved by a walk. Feeling as ifabout to vomit. 9 p.m., humour a little better, extreme weariness, must go to bed. No more Q. taken after this. Had taken in all 0.26 grm.- 17th. For the first days he felt no change in symptoms, the orbital pain especially was persistent. He set out on his travels on 21st, felt much better, but on 22nd all the disagreeable symptoms of previous week returned, with the exception of the urging to urinate. For many days after getting home the orbital pain recurred regularly about 3 p.m. and lasted till 5 p.m. (Ibid., 31.) 28. K-, æt. 24, strong, a great smoker.-Nov. 26th. Began taking daily 0.005 grm. Q. h. m. and e.-Nov. 27th-28th. These 2 d. he could not smoke. Half a cigar caused him to feel extremely ill, cold perspiration broke out, and there was inclination to vomit. On 28th toothache of a rheumatic character in sound teeth, the pains increased when cold air or cold liquids came in contact with teeth ; increased urging to urinate, especially after going upstairs.-29th. Toothache continues,not coming on at any particular time, but coming and going. Urging to urinate continues.-Dec. 3rd. Toothache and urging to urinate continue. For the last few d. there is general relaxation and disinclination for work. There came on a peculiar nervous restlessness which drove him out of the house ; he was unable to remain in his room he felt so impatient. He was no better in the open air, his restlessness was intolerable. Along with this a peculiar confusion of head, not pain. On the 3rd the restlessness became aggravated to perfect anxiety, which caused him to start at every step heard on the stairs, and at every knock at the door. These states became relieved in e . Though he took his dinner as usual, about 6 p.m. voracious hunger set in, which was completely satisfied with a little bit of bread, so much so that he could eat no supper.-4th. N. disturbed by anxious dreams . The symptoms of the previous d. recurred with increased intensity.- 5th. Same symptoms.- 6th . Took no med. this m. Somewhat better. Voracious hunger e. Urging to urinate, and toothache as before.- 7th. Better, but not quite well. Urinary and teeth symptoms continue. No med. taken this e. These symptoms continued with varying intensity during the whole proving, which lasted till 15th . The urging to urinate lasted 8, the toothache 10 d. after leaving off. He took in all 0.18 grm. The pulse and temperature were not sensibly affected. ( Ibid. , 36.)

1. H-, æt. 25, Nov. 27th,began to take daily o'r grm. Qh.- 29th. In afternoon, confused head, which increased gradually to actual frontal headache. Constipation.-30th. The headache reappeared at the same h. with flashing before eyes. Very little urine passed, no stool till e.-Dec. Ist. Headache as before, pressure with vertigo. No stool.- 2nd. Afternoon headache with noise in ears. Appetite increased sometimes to voracity, but was allayed by very little food. Constipation. Headache relieved by drinking beer.-3rd. N. restless, many confused dreams. The confusion ofhead increased during d. to complete stupidity with general prostration. In m., slight nausea with heartburn. At noon, after a very hard stool, transient cutting in bowels.-4th. Slept very ill ; while lying awake at n. heard his name called loudly and repeatedly. During d. the pulse intermitted occasionally.-5th. A bad n. The weakness and stupidity increased during d. The digestion seemed retarded, so that he had in e. eructations of the food eaten at noon.-6th. When reading, great flickering before eyes .- 7th . He observed that he was much more easily affected byalcohol than previously ; 2 to 3 glasses ofbeer made him quite tipsy. Very irritable the last few d.-roth. As no alteration in symptoms occurred, he tookfor 8d. double the dose of Q. h. The stools remained irregular ; every other day bowels were opened 2 or 3 times. The urinary secretion and desire to vomit now became increased. Disposition irritable ; the former depression gave place to excitement. The intolerance of alcohol increased every d. The headache went off, but noise in ears frequently occurred. The nights were always bad, the dreams became of an anxious character ; he often woke in a state of anxiety and fright, having dreamed he was being chloroformed todeath. After leaving offthe Q. the symptoms gradually declined. Pulse and temp. not sensibly affected during proving. He took altogether 0.58 grm. (Ibid., 51.) 30. E-, æt. 23, strong and healthy except that he is subject to palpitation. He began, Nov. 26th, to take daily, m. and e., o'or grm. Q. h.-27th. In e. felt extreme exhaustion.-28th. About 9 p.m. excessive exhaustion and prostration, head confused. -29th. Slept well, but on rising feels the weariness and heaviness of limbs. This went off during d., but suddenly recurred in e. as on previous d. Head confused and violent vertigo. This increased on looking at bright objects and became so intensehe had to go to bed at 9 p.m.-Dec. Ist. Though yesterday he was quite well and slept well last n., he felt very unrefreshed on waking. He felt extremely prostrated, had no inclination for work, was apathetic. After the m. dose these symptoms increased. He had also a tiresome nausea . Rather better after a walk . After his walk he felt weak, as after recovery from a long illness. Better in e.-2nd. No symptoms.-3rd. Well during d. till e., great malaise, ill-humour, headache. No symptoms until Dec. 10th, when he began taking double the quantity of Q. h. Well during d. till e., when symptoms ofgastritis came on. Tongue thickly furred, appetite bad, all food is disrelished.- IIth. Gastric symptoms relieved.- 12th . Gastric symptoms gone, felt very well, but appearance did not correspond. Face bloated, eyelids swollen as if after alcoholic excess. During fore-

noon frequent attacks of vertigo, vision indistinct, gait unsteady. Depressed spirits, melancholy. In e., quite well again.-13th. Forenoon, well. Afternoon, headache till e. Very excited disposition till he went to bed. At 9 p.m. he was so tired he had to go to bed.- 14th. Unrefreshed by his good night's sleep. Violent headache and feeling of great physical exhaustion. Could not get up on account ofviolent attack of vertigo ; disagreeable chilliness all over body, eyeballs heavy, tongue furred and pale, too large for mouth. No appetite, greatfætor ex ore. No desire to evacuate either bladder or bowels as usually occurs in m. About 8 a.m. , profuse perspiration of disagreeable sour smell broke out and lasted till 11 a.m. On rising now, no vertigo but headache continued. Anorexia and general prostration. The sensation of thirst much diminished, a mouthful of water produces the same feeling of satiety as formerly a full glass. Pulse small and difficult to feel. Though there was still no desire to urinate, he forced himself to do so, and nearly a litre of urine of dark colour and intense sour smell was passed. Took the second dose at noon. The weak feeling and headache lasted all d. Occasional noise in ears. No appetite till 4 p.m. No stool to-day. He took no more Q. after this ; total quantity taken 0.48 grm. The symptoms soon went off. (Ibid., 55.) 31. G-, æt. 21 , experimented in the same way as the others. The only remarkable symptoms he observed were that he was easily intoxicated by a couple of glasses of beer, whereas formerly he could drink five without being materially affected. One n. he dreamt of worms, lice, and other vermin. He had occasional urging to urinate, sometimes to the extent of 9 times a d., but the quantity of urine was not increased. He frequently had roaring in ears and itching of skin of back. (Ibid., 59.) 32. D-, æt. 23, strong and healthy.-July 11th. Commenced taking 0.005 m. and e.- 12th. No effect.- 13th. At 3 p.m. sudden quickening of heart's beats with excited feeling. Quieted in e.- 15th. Appetite increased, urine scanty, brown, and with sediment. -17th. Same state of urine. In m. slight headache soon going off. Urine copious and clear. 6 p.m., much itching in chest, back, and arms, lasting 1 h.- 19th. On rising, m., pretty severe pain in 1. supra-orbital region, which went off during a walk. No stool. E. , itching on chest and back.-20th. Bowels open by pills. The supra-orbital pain comes on 1 h. after rising, and goes off in course of m. From this time the dose of Q. was doubled. 3 p.m., palpitation and præcordial anxiety for h.-22nd. No stool. The supra-orbital pain comes on in m. and lasts all d. Afternoon, slight noise in ears with dulness of hearing, going off in h.-23rd. Restless sleep, malaise all d.- 24th. The pain in head very severe from m. Prostration, no inclination for work, some excitement. No stool.- 25th. Bowels opened by pills. Urine clear and copious. No headache. Excitement continues. Afternoon, in spite of dinner, voracious appetite for salt things for h.-26th . Very restless sleep. Wakes with a start, præcordial anxiety and great prostration. Recurrence of pain on 1. of forehead, particularly in supra-orbital region,

lasting till noon . No stool, urine copious and clear.- 27th. Normal stool, urine clear, r. eyelid red and swollen.- 28th. Swelling of eyelid increased. Irritation and itching all d. in both meat. ext. Urine clear and abundant.- 29th . Sleep disturbed by toothache, especially on 1. side in upper and lower teeth. M., general prostration, lasting all d., increasing in e. Urine turbid and scanty.-30th. From 10 to I a.m. sleep sound and calm, and then wakes with anxiety and intense pain in l. orbit and ear. Pain in teeth recurs, and is aggravated by closing jaws. Great thirst, noise in ears, vertigo on rising. For 1 h . sleeplessness, then drowsiness, strange confused dreams until 7 a.m.; thengreat fear ;; then good sleep from 7 to 9 a.m. On waking great prostration, tending to vertigo. Agitation, nausea, great desire to vomit without result. 10 a.m. easy stool. Headache gone, but pain in teeth continues, hindering mastication. Very acute pain under 1. ear. Urine scanty, turbid, contains urates. After a siesta of 2 h. pains all go off.- 31st. Sleep disturbed by pain in head and tooth. Body prostrated, head empty. Headache goes off, toothache slighter. The pain under 1. ear continues. Eyes fatigued by reading. A small furuncle on r. upper eyelid is lanced,and a quantity ofpus isdischarged. No med. to-day.-Aug. Ist. Symptoms all relieved ; pain confined to meatus externus . After another dose vomiting. No stool.-2nd. Pain in meatus increased, lasts all d. No stool. After the evening dose vomiting.-3rd. No sleep on account of violent pain in teeth and l. frontal region. Feels very ill. Face bloated, high coloured. Gets better during d. Bowels moved by pills. After dinner disagreeable sensations in ears as if stopped with cotton wool. E. , eructations and violent pain in temples with strong pressure in skin, which makes it impossible for him to work. All this removed by a walk.-4th. The sufferings which were in abeyance during n. recur in m. Eyes feel as if not open enough, or as if something pinched the upper eyelids down, and prevented distinct vision. This recurred several times during d. The last dose of Q. was taken this m.; total amount taken 0.37 grm. No effect was observed on pulse, temp., or digestion during proving.-5th . Symptoms nearlygone. Duringthe next week, when no Q. was taken, from Aug. 5th to 12th, the neuralgia of 5th pair still continued, generally in m., in supra-orbital region; the pain in teeth came on at n., but these pains were not intense, and did not prevent sleep. Pain in meatus and eyes went off after few d. But several d. later there came on great sensitiveness of gums, which bled at the slightest touch . This lasted 2 weeks. The neuralgic pain in fifth pair went off entirely in the latter half of August, but at the end of this month they returned during the n. of the same intensity, duration, and type as when taking the Q. They spread over the supra-orbital region, 1. temple, and both upper and lower teeth of 1. side. They commenced in teeth, spread over head, and ended in nape. Soon the dental neuralgia increased in intensity, and was only allayed by acupuncture and cold water. The sleep was bad, frequently broken, but in m. the pain was gone. After this the neuralgia came on every n. about 3 a.m. From 3 to 6 a.m. the pain was agonising. There was no pain during d. This state of things lasted 1 weeks. Arsenic in

large doses was given for a length of time without effect. Ferr. oxid. in small doses was more successful, and after taking it for a week the neuralgia disappeared. ( Ibid.)

Volume IV — Appendix

CHININUM ARSENICOSUM.

(See vol. ii, p. 151, 738.)

I. 3. H. L. Northrop, st. 21, tendency to itching eruptions skin. ISC d., took i gr. of i, trit. 2 h. after breakfast, soon followed by itching on neck and scalp lasting 40 m. 1.20 p.m., sharp pain in head, beginning in i. frontal region, shooting towards occiput, and followed by dull sore feeling along track of pain, lasting several m. Itching again on head and sole of 1. foot. 1.40, intense tired feeling in 1. side over middle and lower ribs, like side ache, lasting from 15 to 20 m. 4. to, dull heavy pain in I. side of head while sitting, relieved by walking. Pulse slow and irregular. 5.5, itching, relieved by scratching and then reappearing elsewhere. At 5.20, while bathing, itching of almost entire body ; when using towel fell sore spot over triceps of r. arm. In m. nearly whole of cutaneous surbce over tricepi was bright red, somewhat swollen, and had a burning tender feeling like sun-burn. 5.45, intense itching in a small spot on outer side off. leg. 8, dull pain in r. lateral half of head, followed by desire for stool which was relieved by passage of much Ratus. 1 1, itching reappeared, aggravated by warmth of bed or bedclothes. 2nd d. — 10 a.m., sharp trarisitory pain in 1. leg. 2. 30 p.m., dull continued rheumatic pain in 1. shoulder-joint, aggravated by lying on 1. side. In e, transitory attach of pain in I. shoulder, leaving locality tender. Appetite increased throughout d. Soreness over r. triceps continues, causing burning feeling when touched, [Trans, of Amer. Init. of Horn. y 1888, p, I49.)

1. C. W. Benedict took i gr. 1, trit. An h. later fell slight dull pain in I. temple, occasionally a shooting pain through r. tctnplc This was followed by a dull ache in vertex, lasting an h., and attended with slight nausea. Slight constipation. Appetite improved ; food seemed to taste better than usual. No further effects. {Ihid.)

2. T. L. Macdonald, aet. 27. Took i gr. i, trit. at 6 a.iii- 8.30, .sudden and violent urging for stool, evacuated with prolonged gush until bowels were empty; stool thin, brown and painless. 10.30, simibr stool ; less watery. 3 p.m., dull heavy headache, frontal and occipital, continuing until bedtime. 2nd d. — Headache of similar kind. In e., a peculiar burning ache about sphincter vesic;e and through urethra. 3rd d. — No symptoms. 4th d. — Dose repeated ; no symptoms. 5ch. — Dose repeated at bedtime ; was called up at midnight and could not sleep for 3 h. on returning to bed. 7th d. — Same dose. Constipation, stool dark and lumpy. Dull heavy ache in cerebellum, worse from slightest motion. 8th d. — Less constipated. Dull, stupid

feeling In head, lasting from ncx)n until bedtime. 9th d. — Four soft

stools. Headache slight in m. lothd. — Stool hard again, ilthd. —

Sararxc dose. Slight cerebellar headache p.m. and e. 12th d. — Same

do&^. Urination more -frequent. Slight dull ache in frontal and

occi |>ital regions, lasting till noon. Stool very hard, voided with diffi-

Ol't_y, aided by pressure of finger on tip of coccyx. 13th d, — No

s/i* m ptoms. 14th d. — Same dose. Increased micturition and more

fre*^ «ient. 15th d. — Bladder had to be emptied during n., having had

nocr t urnal emission (probably from distended bladder). Sh'ght headache

in «~*-», No further symptoms. {Jbid.)

^. a. MiLSON R. Allen, health good, uses tobacco and coffee in

to^^cJeration. 1st d. — Took 2 gr. of ox trit. at 10.30 a.m. Woke at

"VV*^ p.m., after an h.'s nap, with feeling of being extremely tired.

During e. had dry mouth and much thirst ; drank 6 glasses of water

^ II p.m. 2nd d. — Thirst continued up to noon, with exhilarated

^tding. At noon severe peculiar feeling about heart, as if a hand suddenly grasped it, and, holding it for a moment, let go ; the symptoms fccurred for a period of 7 m. 3rd d. — Renewal of heart symptoms j no other effect.

b. After several weeks took 2 dr. of 6th dil. in m. About I p.m. became exceedingly evil-disposed ; quiet anger with everybody without cause ; did not care to converse with anyone, rather finding fault when he did so ; imagined he was in a fight with several students, and how he would act had two of them Jumped upon him. This idea continued all afternoon, ending in marked nervousness, hands trembling exceedingly, muscles of arms and legs twitching now and then. At 3 p.m., pains in both 1. and r. chest resembling those of pleurodynia, remaining about an h. They were short, lasting only a m. or more ; pressure upon chest when they were present gave sensation of soreness ; they were dull, aching, as from pressure, with feeling as if he wanted to lift tight-fitting undershirt from chest, and undo vest, which seemed to relieve. 2nd d. — Nervousness still continues, but not so markedly ; mental symptoms have disappeared. Noticed during m. occasionally that objects he might be looking at steadily seemed as if trembling ; this would only last for a second or two. Just before dinner had severe pain in r. instep. During afternoon feeling of general soreness came on in 1. kidney ; seems quite deep, and worse when sitting very erect, better when reclining. Memory seems impaired ; had to work hard to retain or remember what he had read. 3rd d. — Urinated at i .45 a.m., and only once afterwards in d. (at 3 p.m.) ; urine concentrated. General feeling of lightness about head all d., and feeling of exhilaration. No further symptoms noticed. [Ibid.)

1. a. Everett B. Finney, 1st d., took.a dr. of 6th dil. at 12 m. Soon felt sense of warmth all over body, with fufness of head, followed by slight sickly sensation. Throat soon became dry, and thirst developed, remaining great all d. ; appetite increased. 6 p.m., slight pain in stomach, and d. — White glairy discharge from nose ; some cough ; •light pain in bowels ; thirsty all d. ; unable to keep mind on studies as usual ; temp, and pulse not affected. 3rd d. — Soon after awaking at 7.30, spell of coughing, with free expectoration and glairy nasal dis- VOt. lY. "SS

charge ; pain in bowels after breakfast, relievi

frequent pain in bowels, getting worse until rel

brown stool. Breathing not satisfactory, want

take into lungs. Discharge from nose, and coi

continues all d. Another small stool, p.m., pr(

which are relieved by sitting. Difficult to cone

unusually tired on going to bed. 4th d. — Dry

little expectoration. Severe stitching pains, as f

followed by similar pains in prxcordia, worse on

breathing ; it seemed as if air inspired was ins

stairs, short breath and palpitation ; pulse at ti

the shortness of breath and accelerated pulse c

became better when at rest. Occasionally sol

tremities felt weak ; seemed unable to stand

5th. — N. good, and next d. felt quite well,

b. After 2 mo. took i gr. of ii trit. at 5 nauseated, and had sinking sensation at stoi dose at 6.45 a.m. Empty feeling soon e bowels as from gas ; head feels heavy and ( slight pains in r. leg below knee ; all sympton headache mostly right-sided, but shifting aba limbs j feeling in throat as if a piece of mucu) hawking, but he could not accomplish it. 311 weak ; sharp pain in 1. temple at times ; du head \ head feels too full, as if it would burs open air ; pulse slower and weak ; some dry and high-coloured. 4th. — Diarrhcea this m., etool brown, liquid, and containing jelly-lik region, quite severe when walking. Could e: some dinner, and immediately thereafter hai which was watery and blackish ; some pain in and irritable. 5th d. — No symptoms, save sli appetite improved. 6th d. — Awoke feeling w at 9 a.m. P. m. hiccup and belching, folloi 7th d. — At noon felt nauseated and deptessei sneezing. In e. better, so that on retiring he 1 Only symptoms were pain of drawing cha upper and lower jaw, 1. side ; and dry^ holli effects. {Ibid.)

1. a. Joseph Rodes, in good health, ul smokes occasionally. Took i dr. of 6 dil« symptoms during d., but awoke from sleep at inferior angle of r. scapula, worse from movem Soon fell asleep, but when he woke again at^ After breakfast pulse was quicker than usual, \ d. felt soreness in r. brachialis amicus when 3rd d. felt well.

b. After four weeks took another dose of pharyngo-laryngeal catarrh set in, and had n loth d. (As this result is so different from

do not think it well to give the detailed symptoms, but content ourselves with noting the general fact for possible verification. — Eds.)

c. After lod. more again repeated dose, at noon. At 12.30 hiccup. Appetite not good for dinner \ slight disgust for meat. 2nd d. — Stool small, hard, light brown in colour, and difficult to expel. 3rd. d. — Stool same. 4tb d. — Bowels right again, and felt well in every respect. {Ibid.)

1. G. H. Haas, normal health, uses no stimulants — coffee dis- ^reeing. Took i dr. of 6tb dil. without effect. After 1 2 d. made a solution of 10 dr. of same in I2 teaspoonsful of water, and took 2 teaspoonsful every 2 h. firom 9 a.m. to 7 p.m. At 10 p.m. experienced burning sensation in stomach, and passed much flatus per anum. 2nd d.>— 'Awakened at 5.30 a.m. with pain in abdomen below umbilicus, of gnawing character, urging him to stool at 5.45. Stool faecal, with mucus and blood, with considerable tenesmus before and during stool, lasting about \ h., with a little discharge every now and then. Nausea and empty retching during stool. Pain relieved by stool. Foul taste in mouth. 7, same abdominal pain, with urging to stool; more mucus and blood ; tenesmus before and for some time after stool; no nausea on retching; pain relieved by stool. 11, same abdominal pain, stool &c. 3rd d. — 7 a.m., slight pain in abdomen below umbilicus, relieved by a large stool, which was faecal, with little mucus, slightly tinged with blood. No impairment oi appetite all the time, and no alteration in pulse-rate and temp. 4th d. — Stools normal ; no symptoms of any kind. {Ibid.)

Volume IV — Supplement

CHININUM ARSENICOSUM. (See vol. iy pps 1535 7385 vol. ivy ps 544.)

1, 10, a, Of nervous, bilious temperament, cephalic habit, subject to neuralgia, dark, at. 41. On 11th March I took gem, 0°20 of the 3, trit, at 10 a.m, Some vague pains in stomach and limbs became accentuated, perhaps to be attributed to the dry wind then dominant, I did not feel any morbid symptoms and dined with my usual appetite at midday. At’5 of the same day, I took another dose as above. ‘After about an h, dryness of palate, yawning, and nausea, as if on the point of vomiting (resembling the feeling produced at first tobaccosmoking). After about an h. this state of discomfort disappeared and

73i

the n. passed tranquilly. On 1 3th, at 7 a.m., a fresh dose. After an b. frequent yawning came on. Momentary vertigo. Griping or colic about umbilicus as if I had taken purging medicine. My appetite, however, was not sensibly affected. At 4 p.m. another dose. Instantly afterwards deep obtuse pains in 1. femur, already felt after dose taken the d. before. After an h. a dull pain at the 1. temporo-maxillary articulation and in thigh of same side. A sense of being oppressed in anterior mediastinum, at r. side of sternum, transitory ; formication and pricking, especially in scalp. Profound shooting pains all along r. leg, most in repose. At 5.30 repeated yawnings, shiverings, and cold* ness generally ; dull headache. Pains as if wind were confined in the left inflexion of the colon ; pulse 55, ordinarily 61 . General stretching. Penetrating pains in upper temporo -frontal region. Pains at r. astragalotarsal articulation, as if the two surfaces were being drawn in opposite directions, ceasing on walking.

I b. I resumed proving on the 24th with a dose of grm. 05 of the crude substance. Almost immediately (10 a.m.) quivering of facial muscles, especially the orbicularis palpebrarum. After an h. stretchings, repeated yawnings, nausea as if on the point of vomiting, complete lassitude of muscles, chiefly of inferior extremities, as if from being poisoned by tobacco. In walking vacillation and tottering. Prostration as after an acute and severe illness. Urine watery ; pulse 53. Aversion to mental occupation, in spite of lucidity of mind. At midday almost alt the symptoms disappeared i and I dined, feeling the need of it, nevertheless with little taste for my food. 25th. — At 3.30 p.m. a fresh dose of 005 grm. No important symptom all e., with exception of a troublesome weariness at r. shoulder, as if the humerus would be wrenched out of the glenoid cavity. 27th. — At ii a.m., 005 grm. Instantly, dizziness as if I were struck down, which got worse in looking upwards. Deep pains in the wrist, as if the periosteum were affected. Motion did not make them worse, rather rendered them less sensible. On seating myself, my head appeared as if it were covered with a bar of iron. After f h. extreme tiredness with desire to lie down. Urine watery. Stiffness of legs as soon as seated. A return of the dislocative pain of the r. arm. 2gth. — ii a.m., grm. 005. Almost immediately indescribable general feeling of malaise, with increase of flying heat, and relaxation of strength, chiefly in lower limbs. Sense of languor as if I had fasted long. Colic pains about umbilicus. At 7 p.m. (after supper) malaise at epigastrium as if from indigestion, without nausea. The alvine functions tended predominantly to costiveness. The d, after stiffness of all the limbs, troublesome and persistent, also during motion. Obtuse memory with deafness on r, side. From 30th — 31st n. disturbed by pressive gastralgia, which recurred for several mornings, as if stomach were pushed against the spinal column. The food rose again momentarily.

c. On I2th April at 3.30 p.m. I took 10 centigr. of the crude' substance at one dose. Almost immediately constrictive pains at the cardiac region, and after ^ h. copious epistaxis. During whole e. flying burnings here and there over surface of body, as if an electric current had been applied. N. full of visions, heavy somnolence in

m, Great debility of limbs on d, following, with profound pains in articulations, which were not modified by movement, 14th.—At 11 a.m. I took a gramme of the 3x at once. Pains at 1. wrist, with stiffness of arm of same side, Weakness at scrobiculus cordis as if after long fasting. Fluxion from nostrils, especially |., with deafness as if from the noise of bells. ‘he fying burnings and itchings of the cutaneous surface were repeated, also the decp pains in the thighs, which were ‘more ‘elt in repose. A tranquil night. In m, copious atulence, very foetid, without pains in abdomen ; general feebleness with immoderate hhunger. Inaptitude for study and for walking. 17th.—At 7 and at 10 am, repeated dose. Immediately there returned the prostration of the whole muscular system. Pains in abdomen about umbilicus, and in ileum, Tensive gastralgia in correspondence with the desire for eructation. Tasteless eructations which arose only for an instant, Pains in r. knee, as if I had hurt it in falling, which lasted all e., hindering sleep and continued nearly all the following d,; pressure at the tuberosity of the tibia, which was swollen, increased the pain, Pains as of contusion in the deep layers of muscles of thigh and biipte, first to the right and then to the left. ‘The gastralgia was alleviated by food in e,, but the prostration and the feebleness of the limbs continued until’the succeeding d. Feeling of sadness and of being cast down, ‘Taste bitter and metallic, without altering the flavour of any food taken, A burning pain as if in periosteum of 1. elbow. Crampoid drawing in 1, gemellus muscle. The gastralgia, assuaged in e,, returned with more force in m., as if from indigestion of acid fruits of of brown bread badly baked. “At the same time neither nausea, nor bad taste, On rgth the cardialgia continued as if the stomach were contracted over a roughstone. A return of the luxation pain in r. wrist. (Bonixo, L’Omiopatia in Italia, xi, 1889.)