Phytolacca decandra, L.

Natural order , Phytolaccaceæ.

Common names , Poke, Garget-weed.

Preparation , Tincture of the root.

Authorities.

1 , Schultz, Inaug. Thesis, effects of large quantities of the root (from Bigelow, Med. Botany); 2 , Bigelow, Am. Med. Bot., effects of large doses; 3 , same, effects of scruple doses in Dr. Geo. Hayward; 4 , Jahr's New Manual, by Hemptel, symptoms, from Trans. Am. Inst. of Hom., vol. ii (original not to be had); 5 , Dr. S. Rosa, Am. Mag., 1, p. 329, 1851, effects in two young women of taking about 3 ounces of an infusion of 4 to 5 ounces of root in cold water; 6 , Flumiani, Journ. de Chim. Méd., 1858, p. 458, effects of eating the stems, in three boys; 7 , Dr. Donnelly, effects of powdering the root, from Griffith's Med. Bot. (Hale's New Remedies, 2d ed.); 8 , Burt, provings with Phytolacca and "Phytolaccin," Hale's New Remedies, 2d ed.; 9 , Dr. C. H. Lee, Hale's New Remedies, effects of eating a lot of the berries, in a boy; 10 , Paine, "Concentrated Medicines, 1865" (electric), from Hale, effects of 1 to 1 1/2-grain doses in healthy persons; 11 , H. Barton Fellows, from Hale, proving with small doses (1 to 1 1/2 drops) of tincture; 11 a , same, 12 pellets 2d dec. dil., first day, 15 pellets, fourth day; 11 b , same, 8 drops of 2d dec. dil.; 12 , Dr. Marshall, proving with the tincture, repeated doses for four days of 10 drops to 4 drachms, from Hale; 13 , J. Lester Keep, effects of inhaling the powder of the root while grinding it, from Hale; 14 , Dr. ---, proving, from Hale, effects of fumes from slicing the green root; 15 , Griggs, from Hale, effects of 2 or 3 drachms of tincture in a boy six years old; 16 , Warren, Trans. Hom. Med. Soc. of St. of N. York, 1865, effects of chewing and swallowing small bits (3 or 4 grains) of the fresh root; 17 , Bahrenburg, Western Hom. Obs., 3, 126, 1866, effects of eating a small piece of the root; 18 , Cooley, Trans. Hom. Med. Soc. of State of N. Y., 1870, proving with 5 grains, 4 P.M., first day, 10 grains, 8 A.M., third day; 19 , Gilman, Med. Invest., 1871, p. 19, effects on a family of eating the fresh root grated with horseradish; 20 , Rawlings Young, American Practitioner, 9, 380, three children ate the root at 11.30 A.M., and at 12 ate a hearty dinner; 21 , Grasmuck, Ohio Med. and Surg. Rep., 8, 289, a woman suffering from a slight pain in the right hip took, three times a day, a small swallow of an infusion of 3 ounces of P. in a pint of whisky; 21 a , same, effects of smaller doses of same in a man; 22 , C. H. Lee, Bib. Hom., 1874, p. 182, effect on a child of eating the berries; 23 , W. S. Searle (MSS. to editor of this work), effects of eating grated root (by mistake for horseradish), in a man about sixty years old; 24 , same, in another, aged twenty-one; 25 , omitted; 26 , Williamson, Trans. Penn. State Hom. Med., Soc., 1871, p. 179, effects of chewing and swallowing small pieces of the fresh root; 27 , Whipple, Electric Med. Journ., 35, p. 560, a woman suffering from inflammation of right breast took of a solution of 10 drops of tincture in 3 ounces of water, a teaspoonful and in an hour a tablespoonful; 28 , Libby (MSS. to editor), effects of eating the root for a trivial complaint; 29 , Craig, Richmond and Louisville Med. J., 1869, p. 237, a man aged twenty-nine ate half at root six inches long.

MIND

Feeling of intoxication and weakness on rising and walking about (second day), 16.
Increased cheerfulness of the mind, 4.
The mind has been gloomy since I began taking it, and more than usually irritable (fourth day); more cheerful (fifth day), 11.
Great loss of personal delicacy; there appeared to be a total disregard of all surrounding objects, and no disposition to adjust their persons under any circumstances, 5.
Sense of entire indifference to life , and disgust for the business of the day, on waking, early in the morning, 4.*
Indisposition to mental exertion, with the heavy aching feeling in the head and vertigo (after three hours and a half, fourth day), 11a.
The patients in a half stupor all the time, and would fall asleep immediately after a paroxysm of cramping had passed, 19.

HEAD

Vertigo.
Alarming vertigo, with nausea (after half an hour), 5.
Vertigo, 13, 16, 20 ; (after one hour and a half), 29.* [10.]
Vertigo, with dimness of vision, 4.
Dulness, giddiness, and vertigo, 4.
I have sometimes observed slight narcotic symptoms during the operation of Phytolacca, particularly vertigo, 2.
Transient giddiness, 4.
He never noticed any dizziness or stupor from it, although he had always been particular in his inquiries to know if any such symptoms took place, 3.
Slight dizziness, with the heat in the head (after three hours, third day), 18.
General Head.
Head thrown backward to its utmost extent, 5.
Dulness of the head, 4, 19.
Dulness in the head, with the general disturbed feeling in the stomach (after half an hour), 26.
Dull feeling in the head, 4. [20.]
Heaviness in the head, and especially in the temples, 4.
About 11 A.M., a feeling of heaviness or weight in the head, and vertigo began; the heavy feeling extended down through the shoulders and chest, and later in the day through the legs (third day), 11a.
Some heaviness of the head, accompanied by a feeling on the back part of the tongue as if burnt, soon, 11b.
A heavy aching feeling in the head, with vertigo and indisposition to mental exertion (after three hours and a half, fourth day), 11a.
Headache, with sickness at the stomach, 19.*
Headache (after one hour and a half), 29 ; (after third dose, second day); slight all day (third day), 12.
During the forenoon I had a severe headache, which began soon after breakfast; a part of the time the whole head ached; a part of the time the pain was in the temples, and was accompanied by a slight vertigo, and a part of the time the pain was most marked in or confined to the occiput; walking or riding increased the pain, but walking the most (fourth day), 11.
Headache, with sickness of the stomach, from walking, 4.
Headache, 4, 7.
Pain through the whole head of a dull character (after three hours and three-quarters), 16. [30.]
Pains throughout the head aching, 4.
The pain in head is increased by looking down and by stooping, 4.
Moving, transitory pains in various parts of the head, almost constantly, generally in one side at a time, but more frequently and most severe on right side, 4.
No pains in head until leucorrhœa commenced, then had pain through both temples, 27.
Sore pain over the head, worse on the right side and in damp weather, as if an attack of sick headache were approaching, 4.*
Sensation of soreness in the interior of the head, 19.*
Sensation of soreness in the interior of the head, deep in the brain, 4.*
Pressure in the head, as if it would burst, at 3 P.M. (second day), 18.
Many of the symptoms, especially those about the head and throat, are better after breakfast, while the heat and many of the abdominal symptoms are worse, in the afternoon, 4.
Forehead.
Dulness, with sensation of weight in the forehead, 4. [40.]
Dull pain in the forehead, 4.
Dull, steady, aching pain, principally in the forehead, 4.
Dull, heavy headache in the forehead, a constant symptom; sharp, shooting pains in right temple, 8.
Heavy aching pain about the forehead, after dinner, 4.
Dull, pressing pain in the forehead, accompanied by slight nausea, with cool perspiration on the forehead and feeling of weakness (after one hour and a quarter); the nausea and headache were somewhat relieved by eating supper, but soon returned, 16.*
Headache, commencing in the frontal region and extending backward, 13.
Pain in the region of time and mirthfulness, on the right side, 4.
Pain in the forehead and temples very severe, with a feeling of lassitude (first night), 8.
The pains in the head are chiefly in the forehead, and worse after dinner, 4.
One-sided pain just above the eyebrows, with sickness of the stomach, 4.* [50.]
Slight pain in the forepart of the head, with increased sense of hearing, 4.
Slight pain in the tuberosities of the forehead, 4.
Slight fulness of forehead, with constant gaping, 4.
Pressure in the forehead, after dinner, most in the glabella, 4.
Pressure on forehead and upper parts of both eyes, painful, 4.
Slight pressure across the forehead, with gaping, 4.
Slight constriction across the forehead, 4.
Temple.
Severe pain in the temples (after four hours), 18.
Pain in the temples, with pressure outward (after three hours, third day), 18.
Pain in the temples and forehead, at 7 A.M. (second day), 18. [60.]
Pain in the left temple, followed by burning in the skin, in the left region of time, 4.
Drawing pain in the right temple, 4.
Pain and pressure in the temples (after two hours), 18.
Pressure on the temples and constrictive feeling at the præcordia, like the feeling that precedes sea-sickness, 4.
Pressure in the temples, 4.
Pressure in the temples and over the eyes, 4.
Vertex.
Heaviness at the top of the head (soon after fifth dose), 12.
Pain in the top of the head, and a sensation as if the brain were bruised, when stepping from a high step to the ground, 4.
Pressure in the top of the head, with dryness , lasting an hour (fifteen minutes after second dose, second day), 12.*
Headache in the vertex, beginning while riding, at 5 P.M.; motion increased the pain and caused vertigo; pain lasted until I went to sleep at night (after five hours and a half), 11a.
Parietals. [70.]
Throbbing headache on right side, 28.
Occiput.
Pain in the back of the head (after five hours), 15.
Dull, bruised pain in the occiput (after two hours and a quarter), 16.
Pain in the left region of combativeness, 4.

EYE

Eyes deeply sunk in their orbits (after a few hours), 17.
Eyes sunk deep in their sockets and surrounded by a livid circle (after one hour and a half), 29.
Eyes became much inflamed, and tears flowed continually (after three hours), 14.
The eyes ached and were subjectively sore (second day), 24.
Sensation of twitching about the eyes, 24.
Shooting pain from the left eye to the top of the head, which passes off and returns at short intervals, 4. [80.]
Shooting from the left eye to the top of the head, 4.
Pressure in the eyes, 4.
Some painful pressure on the upper part of both eyes and forehead, 4.
Sandy feeling in the eyes, 4.*
Smarting in the left eye, 4.
Sensation in the eyes like that caused by horseradish, 4.
Feeling in the eyes and nose as if a cold would come on, 4.
Burning and smarting sensation in the left eye, with great flow of tears, 4.
The prominent feeling in the eyes is that of smarting, 4.*
The symptoms of the eyes and eyelids are worse in the morning, but the vision is worse in the evening, 4. [90.]
During one of the provings the symptoms of the eyes became so severe that Sulphur was taken as an antidote, and all the subsequent symptoms appeared on the left side, 4.
When enumerating the symptoms of the eyes only, we find the left one most frequently mentioned, 4.
Orbit.
Aching pain along the lower half of the right orbit, 4.
Pressure around the eyes, in the afternoon, as if the eyes were too large, 4.
Pressure over the eyes, 4.
Lids.
Eyes agglutinated and œdematous, as if poisoned (second morning); this state continued two days, 14.
Agglutination of the eyelids, during the night, 4.
Reddish-blue swelling of the eyelids, worse on the left side and in the morning; cannot close the eyes without pain all the forenoon, better in the afternoon, 4.
Soreness on closing the eyelids, 4.
Lids feel as if granulated, and the tarsal edges have a scalded, hot feeling, as if raw (fourth day); granulated, sandy sensation in the lids, with same sensation upon the edges (fifth day), 24. [100.]
The lids felt as if coals of fire were laid upon them, 24.
Sensation as if a grain of sand were lodged under the left eyelid, causing a secretion and flow of tears from that eye, 4.
Smarting in the internal canthi of both eyes, but worse in the left one, and very much aggravated by gaslight, in the evening, 4.
Itching at internal canthi of the eyes, very severe, which causing the application of the finger to rub the eye, the ball became very painful from the slightest pressure, 4.
Lachrymal Apparatus.
Eyes and nose ran freely, like water, for two hours, and stopped shortly before vomiting stopped, 27.
Flow of tears all the time from the eyes, relieved in the open air, 4.
Pupil.
Great dilatation of pupils (after five hours), 20.
Pupils dilated, 28 ; (after one hour and a half), 29.
Vision.
Long-sightedness, 4.
Dizziness of vision now began to be manifest (after four hours and a quarter); impairment of vision increasing (after five hours), 16. [110.]
Diplopia; not only two, but four and five reduplications of an object were apparent; the objects, whether double, triple, or otherwise, were in the same horizontal plane (first day); the diplopia grew worse, in the evening, and again three or four reduplications were visible (second day); the same eye symptoms, with evening exacerbation (third day); diplopia, with twitching (fourth day); only when suddenly raising the eyes to look at a higher object (fifth day), 24.
Obscurity of vision, 22.
Dimness of vision, 4, 9 ; (after one hour and a half), 29.
Aversion to light, 28.
Photophobia, in the morning, 4.

EAR

Pain in both ears, worse in the right one, 4.
Shooting pain in the right ear, very quick, 4.
A sensation of obstruction in the left Eustachian tube, with a rushing sound in the ear of the same side, and a feeling as if the hearing were dull, while at the same time it is sensitive to the most minute sounds, 4.
Irritation in one of the Eustachian tubes, 4.
Increased sense of hearing, with pain in the forehead, 4. [120.]
Increased sense of hearing; the right is most affected, 4.

NOSE

Pustule in the nostril (fifth day), 24.
Flow of mucus from one nostril, while the other is stopped, 4.
Discharge of mucus from one nostril at a time, sometimes one and sometimes the other, 4.
Coryza, 4.
Severe coryza (after three hours, third day; after four hours, fourth day), 18.
Fluent coryza, for two days (after two days), 14.
All the effects of a severe coryza, 7.
Total obstruction of the nose when riding, so that one is forced to breathe altogether through the mouth, and cannot relieve himself by blowing the nose, 4.
Stoppage of the right nostril, 4. [130.]
During the night one nostril was stopped up (second day), 11a.
Sensation in nostril is smarting and stinging, at 9 A.M.; have ridden in open carriage three hours; sensation in throat almost entirely gone, at 1 P.M.; have been in a warm room about two hours and find symptom returning, but less violent, at 5 P.M. (second day), 26.
Sensation in the right nostril as if tickled with a stiff feather (after three hours and a quarter), 26.
He felt first a burning sensation in the nose, then dryness in the throat, which soon produced soreness; then, watery discharge from the nostrils, which increased until the nose became "stuffed," 13.
Drawing sensation about the root of the nose, 4.*
Drawing sensation above the root of the nose, 4.
Feeling in the nose and eyes as if a cold would come on, 4.*

FACE

Sickly-looking countenance; sclerotica and face of a dark-yellow color (second day), 16.
Expression as though suffering from cholera, 6.
Countenance pale and hippocratic, 5. [140.]
Paleness of the face, which looked sunken, blue, and suffering, 19.
Paleness of the face, 4.*
Face very red, almost purple, alternately very pale, 28.
Face flushed, 27.
Suffering intensely with pains in the joints, and bones of the face and head; her sufferings were such that she had not slept for many nights; the pains proceeded from the "nodes," especially on the frontal bone, and resembled very much those of periostitis, 21.
Pain in the superior maxillary and teeth, at 11 A.M. (second day), 18.
Pain in the superior maxillary (after three hours, third day), 18.
Jaws ached awfully the whole time; seemed as though could not open or stir them, 27.

MOUTH

Teeth.
Teeth all ache, are very sore, and feel elongated, 8.
Shooting pains in the molar teeth of the upper and lower jaws of the right side, 4. [150.]
Irresistible inclination to bite the teeth together, 4.
Tongue.
Tongue coated white, 9, 22.
A white coating made its appearance on the tongue the third day; it still continues (sixth day), 12.
Tongue coated yellow, and dry (after three hours, third day), 18.
Tongue swollen and yellow, 24.
Tongue feels rough, with blisters on both sides, and a very red tip; great pain in the root of the tongue when swallowing, 8.*
Tongue and lips dry, 28.
Great pain in root of tongue, fauces, etc ., 8.*
A feeling on the back part of the tongue as if burnt accompanied the heaviness of the head, 11b.
Slight feeling of smarting and coldness towards the tip of the tongue, 4.
General Mouth. [160.]
Great congestion and swelling of the soft palate and tonsils; the right tonsil is half as large again as the left; both are of a very dark red, 8.
Swelling of the soft palate, 4.
Small ulcers on the inside of the right cheek, like those caused by Mercury, 4.
Tenderness and heat in the roof of the mouth and on the tongue, 4.
Dryness of the palate, in the morning, 4.
Saliva.
Profuse secretion of saliva each day, 12.
Profuse secretion of saliva, in the morning (second day), 12.
Constant flow from mouth, throat, and salivary glands of a thick, ropy, tenacious secretion (after two hours and a quarter), 16.
Secretion of saliva increased, 13.*
Mouth fills with water, 4. [170.]
Flow of saliva into the mouth, 4.
The saliva is yellowish and has a metallic taste, 4.
Cold, sticky, stringy saliva, 24.
No saliva, 27.
Taste.
Metallic taste in the mouth (fourth and fifth days), 12, 8.
Taste like nuts, in the mouth, 4.
Taste, bitter at first, but leaving a slight feeling of smarting and coldness towards the tip of the tongue, 4.

THROAT

Redness and soreness of the throat (after third dose, second day), 12.*
Sore throat and swelling of the soft palate, in the morning, with a thick white and yellow mucus about the fauces , after the removal of which the throat feels better, and still better after breakfast, 4.*
Soreness of the throat, and a feeling when swallowing saliva as if a lump had formed there; the same sensation is felt on turning the head to the left side, 4.* [180.]
*Throat sore; the isthmus congested and of a dark-red color; dryness of the throat, with some swelling of the tonsils, 22.
*Throat felt sore, fauces congested and of a dark color; dryness of the throat; the tonsils were a little swollen, 9.
Sensation of rawness and scraping in the throat and tonsils , as if something had lodged at the root of the tongue (second day), 16.*
Feeling of rawness and excoriation in the throat (after three hours and three-quarters), 16.*
Roughness and rawness of the throat, 8.*
Feeling in the throat as though it was burned (after four hours), 18.
Pain and suffocation in the throat, fauces, and lungs (after three hours, third day), 18.
Pain and suffocating feeling in the throat and lungs (after two hours), 18.
While riding, in the forenoon, a sensation of a plug in the throat, not relieved by hawking; this sensation was replaced by an increased discharge of mucus from the posterior nares, which was detached with difficulty, and which continually excited a disposition to attempt to expel it (fourth day), 11a.
Sensation of a lump in the throat, 4. [190.]
Sensation as of a lump in the throat, that causes a constant inclination to swallow; sensation as if an apple-core had lodged in the throat, 8.
A sensation of the throat being so full that it felt choked; hawking to rid the throat and posterior nares of mucus ; the raising of the mucus succeeded the feeling in the throat; a sensation of fulness and as if something had lodged on the left side of the throat came on after bending the head forward in writing, and was aggravated by turning the head to the left, 11b.*
Pressing pain in the right side of the throat, 4.*
The throat feels very dry and sore , especially on swallowing, in the afternoon, 4.*
Throat very dry, rough, and sore , with a feeling of a lump therein, 19.*
Dryness of the throat, which soon produced soreness, 13.*
Dryness, soreness, roughness, and redness in the throat, all the time (fourth day), 12.*
Great dryness of the throat, 4, 8.*
Dryness in the throat, on going to bed, 4.
Dryness in the throat, worse in the morning, 4. [200.]
Felt the medicine all the way from the throat down into and through the abdomen, 27.
Tonsils.
Tonsils and palate congested, and of a dark-purple color, 8.*
Tonsils sore and somewhat swollen , in the morning (second day), 12.*
Tonsils red and swollen (after third dose, second day), 12.*
Fauces.
Eruption in the fauces and œsophagus (after three months), 21.
General soreness of the posterior fauces, and apparent extension of the irritation into one of the Eustachian tubes, 4.*
The fauces experienced an uneasy sensation of dryness, which provoked a hacking and dry cough (after twenty minutes), 5.*
Slight fulness in the fauces (first day); sensation of fulness in the fauces and upper part of the larynx, and a sensation as of a lid there, which lasted until afternoon (soon, second day); the same feeling of fulness that was previously noted, with a disposition to hawk up mucus from the throat, though none could be raised (third day), 11.
Feeling as if a ball of red-hot iron had lodged in the fauces and whole length of the œsophagus, when swallowing; the pain was so great that I could eat nothing but fluid for two days; constant choking sensation, 8.
Smarting in the fauces (after a few minutes), 11a.* [210.]
Dryness of the fauces, most in the morning, 4.
Sensation of dryness of a spot in the fauces on the left side, in the morning, continuing until after breakfast, 4.
Pharynx.
Roughness in the pharynx (constantly), 8.
Roughness in the pharynx, 4.
Unpleasant sensation of dryness in the pharynx, towards morning, which makes him cough, 4.
Sensation in the pharynx like that caused by eating choke-pears, 4.
Dry sensation in the upper part of the pharynx, disposition to hawk and clear the throat, without affording relief (after three hours and a quarter); dryness of the pharynx and hawking still continues; have raised several small pieces of tough, sticky mucus, at 9 A.M.; have ridden in open carriage three hours; sensation in throat almost entirely gone, at 1 P.M., have been in a warm room about two hours, and find symptoms returning, but less violent, at 5 P.M. (second day), 26.*
Swallowing.
Difficulty of swallowing, which became so severe that he was unable to swallow even water; every attempt to swallow was attended with excruciating-shooting pains through both ears, 13.*
Could not swallow because the throat felt so dry and rough, 28.*
External Throat.
A very peculiar pressure and tension in the parotids, 4, 8.

STOMACH

Appetite. [220.]
Raging appetite, 4.
Hungry soon after eating, 4.
Canine hunger, 8.
The usual appetite remains, notwithstanding the nausea of the stomach, 4.
Diminished appetite, 4.
Little or no appetite for several days, 17.
Loss of appetite, 8.
Thirst.
Intense thirst (after one hour and a half), 6 ; (after five hours), 20.
Thirst, towards morning, with the feverishness, 27.
Considerable thirst (first night), 17.
Eructations. [230.]
Continued eructation of gases while vomiting, 27.
Eructations of sour fluid, 8.
Eructation of flatus, 4.
Eructations, with spitting of water, 4.
Eructations of air, 8.
Eructations, 4.
Regurgitation of food through the evening and until I went to sleep, 11b.
Hiccough.
Hiccough, with great inclination to vomit, but no nausea, 8.
Nausea and Vomiting.
Effects first felt on awaking from an after-dinner nap; nausea, which passed off and recurred in ten minutes, again passed off and recurred, was first felt after two hours, 23.
Nausea, with the vertigo, immediately followed by violent retching and vomiting, ejecting the contents of the stomach, which consisted of the ingesta (after half an hour); vomiting now continued at intervals of from one to five minutes, ejecting a transparent mucus, slightly tinged with yellow, 3. [240.]
Nausea, on being awoke out of sleep, in the night, 4.
Sickness of the stomach accompanying the headache, 4.
Feeling of sickness, as if he would vomit, 4.
Sickly feeling in the stomach, 29.
Nausea, with a very faint feeling, 8.
Nausea, with severe pain in the umbilical region, 8.
Nausea (after one hour), 6.
Nausea, with the heat in the head (after three hours, third day), 18.
Slight, nausea, with the dull pressing pain in forehead (after one hour and a quarter); somewhat relieved by eating, but soon returning with increased severity; commenced to vomit ingesta; vomited violently at intervals of ten or fifteen minutes; nausea relieved, and pain in forehead increased by vomiting (after two hours and a quarter); vomited an acrid substance, which caused a feeling of scraping and excoriation in the throat (after three hours); continued acrid vomiting; took a glass of warm water to prevent the empty retching which was becoming very painful (after three hours and three-quarters); drank another glass of warm water, and vomited again in ten minutes (after four hours and a quarter); drank a cup of strong coffee, which the stomach rejected in fifteen minutes (after four hours and three quarters), 16.
Slight nausea most of the time (second day), 18. [250.]
Slight nausea, with profuse vomiting, without much pain attending it, but a good deal of distress in the stomach, 8.
Nausea and violent vomiting, the ingesta of a dark-red color, 9.
Nausea and vomiting, the ingesta of a dark red color, 22.
Nausea, followed soon by vomiting, and purging, continuing for about six hours (after two hours), 24.
Deathly sickness all the time; position made no difference about sickness, 27.
Violent vomiting, 1.
Vomiting severely and frequently (after half an hour), 29.
Violent vomiting of clotted blood and slime, with retching, intense pain, and desire for death to relieve, 19.
Seized so suddenly with violent cramps and vomiting that they had no time to get to bed, but lay upon the floor, unable even to call for assistance (after half an hour), 19.
Free vomiting at intervals of twenty or thirty minutes (after one hour and a half); continued to vomit until 6 A.M. (second day), 20. [260.]
In about two hours after the second dose he complained of feeling sick at his stomach, and in a few minutes more violent vomiting began, first of food, then of greenish matter, finally of a dark black matter, mixed with clear blood; it required great effort to vomit; this symptom continued nearly all night, but was somewhat relieved in the morning, and at 2 P.M. had ceased, 28.
Soon after, all who had eaten of it began to vomit; the matter ejected was first the aliment and a dark bilious substance, which came away with as little effort as vomiting in Asiatic cholera; the vomiting and purging continued all the afternoon, but the vomiting ceased after taking black coffee; the emesis took place every fifteen or twenty minutes, 17.
In one case there was no vomiting, but most profound prostration, 6.
Repeated vomiting in two cases (after one hour), 6.
Vomiting, with but little distress in the stomach, 4.
The vomiting was without effort and easy, no taste, but bitter, 27.
A scruple was administered by him in nearly thirty cases, in all of which, except in one case, it operated as an emetic, usually three or four times thoroughly, though not severely, generally commencing its operation on the stomach in an hour, and rarely continuing longer than four. He found it to excite little or no nausea previous to its operation, and though it made a powerful impression on the system, it never produced any disagreeable or unusual symptoms, 3.
Ten grains of the powder will rarely remain on the stomach, and twenty or thirty produce a powerful operation by emesis, and generally by catharsis. In its mode of operation this medicine has some peculiarities, a part of which are favorable, others disadvantageous. Its advantages are, that it operates with ease and seldom occasions pain or cramp. Its disadvantages are: 1. That it is slow in its effects, frequently not beginning to operate until an hour, and sometimes two hours, after it is taken. 2. That it continues to operate for a greater length of time than is usual for emetics, although, as far as I have been able to observe, it is readily checked by an opiate. These disadvantages, however, are not constant; I have repeatedly known it commence operating in fifteen minutes, and cease after four or five ejections. The representations of patients as to any unpleasant feelings under its effects are not greater than we should naturally expect, when it is recollected that no emetic is altogether comfortable in its operation, 2.
The substances vomited appeared dark-brownish in color at first, afterwards light-yellow, 24.
Soon commenced vomiting, first the contents of stomach, and afterwards a bitter watery mess, which continued almost incessantly from 9.30 P.M. until 5 A.M., 27. [270.]
During the third attack of nausea colic and purging began; the pain was not severe, and had no special characteristic; he vomited and purged ten or twelve times with so little discomfort, that he calls it the best evacuant that he ever took, 23.
Stomach.
Tenderness to the touch of the pit of the stomach, 4.
Epigastric tenderness (second day), 20.
Feeling of weakness at the stomach, which caused frequent yawning, that was attended by a stitching pain through the part, 11b.
Great oppression of the epigastric region, with a sensation of weight (after one hour and a half), 6.
Burning pain in epigastric region (after one hour and a half), 29.
Great distress in the stomach and bowels, 8.
In great agony; complained of his stomach, where he felt constrictive gripings, 22.
In great agony; he complained of his stomach, saying that it was pinched together, 9.
General disturbed feeling in the stomach, with dulness in the head, increasing for an hour (after half an hour); felt better immediately on going into the open air; sat down to tea; unpleasant feeling in the head and stomach returned; could eat nothing; head and stomach symptoms have nearly all disappeared (after three hours and a quarter), 26. [280.]
When completely aroused from their narcotism, they complained of intense epigastric pain, great thirst, and chilliness (after five hours), 20.
Severe pain in the stomach, on pressure, causing him to cry out, 9.
Pain in the stomach (after five hours), 15.
While riding, I had a simple aching pain in the region of the pylorus, which gradually worked up into the chest on the same side (after one hour and a half, third day), 11.
With the stools much pain in the stomach, upon pressure, which made him cry, 22.
Pain in the region of the pylorus, 4.
Pains in the cardiac portion of the stomach, aggravated by a full inspiration and by walking, 8.
The pain at the pit of the stomach felt like a pain resulting from traumatic injury, 5.
Bruised and sore feeling at the pit of stomach, with pain in the same place (second day), 16.
Intense burning pain in the stomach and bowels, which seemed swollen, and became very sore (after two hours, and again at 9.30 P.M., third day), 24. [290.]
A burning sensation in the stomach, with tenderness of the bowels, and a peculiar heat in the rectum, which is soon followed by tenesmus and mucous and bloody discharges, 10.
Violent pressure in the stomach, on waking, in the morning, with accumulation of water in the mouth; disappears after rising, 4.
Cutting in the pit of the stomach and in the abdomen, 4.
Cutting-tearing straining pains in the stomach, followed by soreness to pressure, 19.
Heat in the stomach, after taking the drug (third day), 12.
The symptoms of the stomach, throat, and mouth are worse in the morning, 4.

ABDOMEN

Hypochondria.
Heavy aching pain in hypochondrium, which left as soon as leucorrhœa commenced, 27.
Digging pain in the right hypochondrium, in the upper and outer portion of the liver, preventing motion; first felt at 2 P.M., then every morning before daylight, some soreness remaining through the afternoon and evening, 4.
Cannot lie on the right side, after midnight, on account of penetrating pain in the right hypochondrium, 4.
Violent dull pressing pain in the left hypochondrium, in the evening, so that he cannot remain in the sitting posture; he lies on the painful side all night, and the pain is gone the next morning, 4. [300.]
Recurrence of pain in abdomen, in evening (this pain finally located itself in the splenic region), (fourth day), 24.
Pain in the left hypochondriac region, when walking, 8.
The diarrhœa appears to be kept up by the increased action of the liver and consequent redundancy of bile, with but little tormina and tenesmus, 4.
Umbilical.
Constant dull pain in the umbilical region, worse by motion, 8.
Great distress in the umbilical and hypogastric regions, 8.
Burning distress in the umbilical region, 8.
Burning-griping pains in the umbilical region, 9.
Burning-griping pains in the region of the umbilicus, 22.
Violent cramping pain about the umbilicus, soon followed by a copious discharge from the bowels, 5.
Boring pain to the left and a little above the umbilicus continuing but a few minutes, 4. [310.]
Severe colicky pains in the umbilical region, 8.
A pain which commenced at the scrobiculus became intolerable, 5.
Pain in the umbilical region, with desire for stool, 8.
General Abdomen.
Frequent passage of wind downwards, 4.
Wind passes the bowels constantly, of a very fetid nature, 8.
Flatus was abundant, 14.
Emission of flatus relieves the pain in the bowels, 8.
Rumbling noise in the bowels, 4.
Rumbling in the bowels, sometimes with desire for stool, 8.
Great rumbling in the bowels, with pain in the umbilical region, 8. [320.]
Bowels very tender on pressure, and pain severely when walking, 8.
Very weak, especially in the abdomen (second day), 17.
Considerable griping pains and cramp in the abdomen, with the purging, in the afternoon (first day), 17.
Griping pain in abdomen, as before a diarrhœa, 19.
Griping in bowels (after one hour and a half), 29.
Griping pains, without diarrhœa, 4.
Griping all day long, followed by the passage of offensive flatus; the griping disappears in the night, 4.
Griping pain, as before a diarrhœa, 4.
Sensation in the bowels as if a diarrhœa would follow, 4.
Bowels felt like moving, but did not, 27. [330.]
Cutting in the abdomen, 4.
Some of the abdominal symptoms disappear in the night, 4.
Pain in the region of the transverse colon, at 7 A.M. (second day), 18.
Deepseated but not severe pain in the left iliac region, 4.
Neuralgic pain in the left groin, 4.

RECTUM AND ANUS

If continued it produces permanent hæmorrhoids, 10.
Peculiar heat in the rectum, with the burning sensation in the stomach, 10.
In the middle of the night, neuralgic pain shooting from the anus and the lower part of the rectum along the perineum, to the middle of the penis, followed in a few minutes by a neuralgic pain in the right great toe, 4.
Continual inclination to go to stool, with much straining, 19.
Continual inclination to go to stool, 4.

STOOL. [340.]

Violent purging, 1.
Purging, severely and frequently (after half an hour), 29.
Severe purging after the vomiting; the stools were thin, dark-brown, 9.
Diarrhœa, with sickly feeling in the bowels; copious discharges of blood, mucus, and what looked like scrapings of the inner surface of the intestines ; involuntary stools, from straining, which continued even in sleep, 19.
Purging all the afternoon, with considerable griping pains and cramps in the abdomen; in the night the passages were without pain; the diarrhœa continued several days, 17.
Diarrhœa, which lasted three mornings, after the other symptoms had passed off; the dejections were very abundant, and did not cease until they became almost watery; they came on at 1 or 2 A.M., and lasted until after breakfast, 14.
At the same time the vomiting began diarrhœa set in, with fearful tenesmus; could not leave stool for a moment; the pain did not cease for an instant; the stool was at first yellow, then of greenish matter, finally dark bloody matter, this continued all night, and in the morning was somewhat relieved, and at 2 P.M. had ceased, 28.
Diarrhœa, attended with a sickly feeling in the bowels, but no tormina or tenesmus, 4.
Purging (after one hour and a half); half ceased (fifth hour), 20.
Purging, 7. [350.]
Purging continued for about six hours (after two hours), 24.
Copious discharge of bile from the bowels, 4.
Copious discharge from the bowels, soon after a violent cramping pain about the umbilicus, 5.
If continued, it sometimes produces dysentery, 10.
Had usual full and satisfactory stool, at 9.30 A.M. had another full stool, unusual , at 2.30 P.M.; another natural stool, very unusual, at 7 P.M. (second day), 26.
(The bowels, which have been more than usually loose for the past six weeks, have been more regular since I began taking the medicine (fourth day); more constipated), (fifth day), 11.
Three stools during the day, the first one is hard and preceded by griping, and the others with pains moving about in the abdomen, 4.
After the vomiting had ceased, there were a number of liquid, dark-brown stools, with much pain in the stomach upon pressure, which made him cry, 22.
Mushy stool, 4.
Stools during the first days light-yellow, loose, and very loud, 24. [360.]
Mucous and bloody discharges and tenesmus soon follow the heat in the rectum, 10.
Stool soft and mushy, with undigested food in it, sometimes with straining, 8.
Stool of mucus, with straining, 8.
Stool soft and mushy, 8.
Soft papescent stool, followed by a very faint feeling, 8.
Dark, papescent stools, with undigested food in them, 8.
Dark lumpy stool, 8.
Hard stools, 4.

URINARY ORGANS

Weakness, pain, and soreness in the region of the kidneys, 19.
Weakness, dull pain, and soreness in the region of the kidneys, most on the right side, and connected with heat, 4. [370.]
Uneasiness down the ureters, 4.
Straining to pass water, 19.
Copious nocturnal urination, 4.
Neither emesis nor catharsis took place until the latter was prompted by the use of castor oil, 15.
Retention of urine, for ten hours, 15.
Slight suppression of urine with the pain in the loins (after three hours, third day), 18.
The urinary secretion was at first diminished, afterwards increased; the urine remained acid and became decidedly albuminous ; the specific gravity became greatly increased; the bottle used to measure the urine became completely covered with a white deposit about one-sixteenth of an inch thick, 8.
Urine double in quantity and clear as water, the last two days (fourth day), 12.
A chalklike sediment in the urine, 4.

SEXUAL ORGANS

Sharp pain running up each spermatic cord (one hour after second dose, third day), 12. [380.]
Hard grinding pain shooting up both spermatic cords, in the morning (fourth and fifth days), 12.
Continual soreness of the spermatic cords, instead of the paroxysmal pains experienced on the preceding days (sixth day), 12.
A gurgling sensation in the prostate gland, repeatedly in the afternoon, 4.
The woman was in her seventh month of pregnancy, and came near having a miscarriage; bearing-down pains; involuntary straining, and hæmorrhage per vagina; pains like labor pains; could feel the uterus contract under my hand, the uterine pains continued at intervals the second day, 19.
Towards morning a leucorrhœa commenced, which was profuse, ropy, and not irritating, 27.
Sensation as though the courses would appear, all the time, 27.

RESPIRATORY ORGANS

Larynx and Trachea.
Sensation of roughness in the bronchia, 4.
Tickling in the left side of the larynx, with hacking cough, and aching in the right side of the breast, and great dryness of the throat, 4.
Dryness of the larynx (one hour after fourth dose), 12.*
Dryness in the trachea, in the morning (second and third days), 12. [390.]
Feeling of dryness in lower part of the trachea and large bronchus (after third dose, second day), 12.
Sensation as if the trachea were strongly grasped; evening, grew worse (after fourth dose), 12.
Voice.
Hoarseness (after one hour and a half), 6.*
At times there is hoarseness, but this is not continual (fourth day), 12.
Cough and Expectoration.
Dry cough (second and third days); with but little expectoration (fourth and fifth days), 12.
Dry bronchial cough, with the sensation of roughness and slight increase of heat in the trachea and bronchi, 4.
Cough, towards morning, from dryness in the pharynx, 4.
Hacking cough, 4.
With the increase of the secretion of bile, there is a dry irritative cough, and almost constantly recurring transitory pains in different parts of the head, 4.
Cough, with expectoration of a tough mucus (after two hours), 18. [400.]
Almost constant expectoration of a tough mucus (after four hours), 18.
Respiration.
Shortness of breath, 4.
Inspiration short and sighing, 20.
Difficult breathing; inability to breathe through the nostril, 13.
Feeling as though I were breathing through an open sponge (after four hours), 18.
Continual moaning and gasping for breath, 3.
Sighing slow respiration, 5.
Breathing shallow (after one hour and a half), 29.

CHEST

Pain and suffocation in the lungs, throat, and fauces (after three hours, third day), 18.
Pain in the lungs, at 7 A.M. (second day), 13. [410.]
Severe pain in the right lung (after four hours), 18.
Pain in the left lung (after three hours, third day), 18.
Pain in the chest with the restlessness (first night), 18.
Tenderness of the muscles of the chest, as if they were bruised, 4.
Pain in the right side of the chest, so bad after midnight as to prevent sleep; aggravated by lying on the right side; disappears after getting up, in the morning, 4.
Pain in the right side of the chest, about the region of the nipple, passing through to the back, felt on taking a long breath, and on bending the shoulder backwards; better in the afternoon, 4.
Aching pain in the right side of the breast, 4.
In the night I awoke with a lameness in the left side, near the cardiac region, with much nervous restlessness; could not get to sleep again for a long while; the lameness was felt whenever I moved, but more particularly during expiration (fourth night). (These pains through the chest appeared occasionally for some months after I took the last dose), 11.
Some lameness in the left side of the chest and shoulder (fifth day), 11.
(Swelling of breast began to leave at once, and almost entirely disappeared, leaving only a small bunch in site of old cicatrix), 27. [420.]
The symptoms of the chest are worse after midnight, better in the afternoon, and most of them on the right side, 4.

HEART AND PULSE

Constrictive feeling at the præcordia, with pressure in the temples, 4.
Great pain in præcordial region, very much worse by walking, 8.
Occasional shocks of pain in the region of the heart, and as soon as the pain in the heart ceases, a similar pain appears in the right arm, 4.
Could feel the heart beat very distinctly, 28.
Pulse rapid, 28.
Pulse rapid and very feeble (after five hours), 20.
Pulse 80 (before the proving); 84 (after third dose, second day, and remained so during the proving), 12.
Pulse 110, full but soft, at 3 P.M. (second day), 18.
Pulse over 100, 13. [430.]
Pulse hard and full, at 7 A.M. (second day), 18.
Tense, strong, full pulse, of about 100 per minute, after he had just ceased to purge, 23.
Pulse very low, towards evening (after a few hours), 17.
Pulse slow and feeble (after one hour and a half), 29.
Pulse small, depressed (after one hour and a half), 6.
Pulse small and threadlike, irregular, and with much agitation in the chest, especially about the region of the heart, 3.

NECK AND BACK

Hardness of the gland on the right side of the neck, 4, 8.
Stiffness in the right side of the neck , worse in bed, after midnight, 4, 8.*
Neck has felt stiff for several nights (seventeenth day), 24.*
Awoke in the morning, with stiffness about the neck (second day), 12. [440.]
The back is very stiff, every morning, 8.*
Towards evening, while riding, a laming pain began in the left side of the back, below the shoulder-blade; at 9.30 P.M., the pain had reached the region of the spine, and was of a pricking, stitching character (fourth day), 11.
Severe pain behind the scapulæ, when walking, 8.
Intense griping pain in small of back, 19.
Pain in the back of the neck, running down the spinal column, at 11 A.M. (second day), 18.
Pain in the loins, with slight suppression of urine (after three hours, third day), 18.
Pain in the left lumbar region, followed immediately by severe itching, 4, 8.
Constant, dull, heavy pain in the lumbar and sacral regions , aggravated by motion, 3.*
Pains shooting from sacrum down both hips (outside) to feet. This was kept up all the time, 27.*

EXTREMITIES

Intense cramps of the extremities; they would gather the muscles into great knots, hard and ridged, coming on suddenly, continuing a few moments, and then in a moment they would be flaccid and sore, 10. [450.]
Rheumatic symptoms in all the joints, at 3 P.M. (second day), 18.
Sudden translation of internal pains to the extremities, 4.
The pains in the extremities are always in the outer portion of the limbs, 4.

SUPERIOR EXTREMITIES

Shoulder.
Both shoulder-blades ached all the time, 27.
Left shoulder ached for some time, about noon (fourth day), 11.
Pain throughout the muscles of the left shoulder, 4.
For several days pain in right shoulder-joint, only felt on sudden motion (seventeenth day), 24.
A lasting pain in the left shoulder-blade, as if from a blow, 4, 8.
Dull aching pain and tenesmus along the top of the right shoulder, along the superior edge of the trapezius muscle, increased by pressing upon the part and by contracting the muscle, 4.
Sensation of weight and pressure on both shoulder-blades, as after carrying a heavy load, 4. [460.]
Sensation of weight and pressure of both shoulder-blades, 19.
Sensation of weight and pressure on both shoulder-blades, as after carrying a heavy load, 8.
An occasional sensation as if a small piece of cold iron were pressed on the painful shoulder-blade, 4, 8.
Severe rheumatism in the left shoulder, 21a.
Arm.
Arms ache, 8.
Spasmodic jerkings of the arms and legs, 9.
Arms were almost paralyzed; no strength in them; could not lift the babe, 27.
Weakness and aching in the bone of the right arm above the elbow, aggravated by motion and extension, 4.
Dull aching pain and excessive tenderness, as if from a bruise, in the muscles of the outside of the right upper arm, most severe for about two inches above the elbow, felt particularly when the part is pressed upon and touched, and when extending the arm, 4.
Pain appears in the right arm after a similar pain ceases in the heart, 4. [470.]
Pain at the humeral insertion of the left deltoid muscle, 4.
Slight drawing pains in the right upper arm, 4.
Tenderness in the outside of the left arm just above the elbow, when pressing upon it, and when extending the arm, 4.
Twitching and fluttering of the muscles of the right upper arm, while it is resting on a table, 4.
Forearm.
The forearms ached after going to bed; the pain seemed to be in the bones, and was uninfluenced by position (first day), 11a.
Rheumatic drawing in the right forearm, 4.
Rheumatic drawing in the left forearm along the ulna, and the same sensation in the right leg, 4.
Hand and Fingers.
Spasmodic jerkings of the hands and legs, 22.
Rheumatic pains in the hands and feet, sometimes in the arms and legs, 4.
Drawing pain in the right hand, now and then, by shocks upwards to the elbow, 4. [480.]
Rheumatic pains, first in the left hand, and afterwards in the right one, 4.
Neuralgic pains in the palm of the right hand, 4.
Rheumatic feeling in the little finger of the right hand, very annoying when writing, 4.
Occasional frequent sudden pricking in the points of the fingers, as if from electric sparks, 4.
Lancinating pain in the little and ring fingers of the right hand, 4.
Violent shooting pain in the fleshy part of the left thumb, lasting about half a minute, 4.
Shooting, like needles, in the end of the left thumb, 4.
Shooting in the finger-joints, sometimes in one hand and sometimes in the other, 4.
Ends of the fingers all throb and ache, as if they were going to suppurate (this symptom lasted three days), 8.

INFERIOR EXTREMITIES

Weakness of lower extremities; could walk with difficulty, 8. [490.]
Lower extremities very weak; could not stand up, 27.
Heaviness in the lower extremities, as if they were asleep, in the afternoon, 4.
The symptoms of the lower extremities are worse in the afternoon, 4.
Severe cramps in lower extremities (after one hour and a half), 29.
Thigh.
Neuralgic pain on the outer side of the left thigh, 4.*
Neuralgic pain in the external part of the left thigh, 4.
Neuralgic pain in the external part of the right thigh, 4.*
Sciatica, 4.*
Knee.
Heaviness in the knee-joints, tired from a little walk, 4.
Pains in the knees and arms, with the restlessness (first night), 18. [500.]
Rheumatic pain in the right knee, in the afternoon, increasing in the open air, and especially on a damp day, 4.
Rheumatic feeling in the left knee, with the sensation of shortening of the tendons behind the knee, when walking, 4.
Leg.
Legs ache and feel very stiff about the knees, aggravated by walking, 8.
Rheumatic pains below the knees and in the arms, 4.
Rheumatic drawing in the right leg and in the left forearm along the ulna, 4.
Severe pains through both ankles and feet, 27.
A stinging pain in the left instep, relieved by pressure (second day), 11a.
Foot and Toes.
A striking pain in the ball of the left foot, which lasted about half an hour (after three hours, fourth day), 11a.
Pains at a spot on the ball of the right foot, which had been frostbitten years before, and in a corn never painful before, 4.
Pain on dorsum of right foot, at four o'clock in the morning, 4. [510.]
Neuralgic pain in the right big toe, in the middle of the night, 4.

GENERALITIES

Extremities stiff; hands firmly shut; feet extended and toes flexed; eyes bleared and dancing; pupils contracted; lower lids drawn down; teeth clenched; lips everted and firm; muscular rigidity was general and opisthotonos established; the circulation numbered 85 beats per minute; pulse soft and unresisting; respiration difficult and oppressed; mucous râle, distinct and audible anywhere in the room; the contraction of the masseters, precluded the idea of addressing remedies by mouth, and the amount of mucus in the bronchiæ that of administering anæsthetics (after one hour); during the next hour he had increased muscular rigidity generally, with convulsive action of the muscles of the face and neck (the chin drawn closely down to the sternum), which condition would last five or ten minutes, to be succeeded by partial relaxation, and return in twenty minutes more with the same violence, 15.
Great desire for cold water, to be bathed in it; could scarcely keep him from dashing water over himself, 28.
In some instances convulsions, 1.
The secretion of tears, saliva, bile, urine, and the menses is increased, 4.
Faintness; felt as if he would fall, and grasped objects for support (after two hours), 24.
Faintness (soon), 29.
Extreme faintness, 5.
Felt very weak (second day), 28.
Began to feel general weakness and discomfort (after three hours), 14. [520.]
Great prostration accompanying the vomiting and purging; much debility, 8.
Feeling of weakness, with the dull pressing pain in forehead (after one hour and a quarter), 16.
Weakness (after one hour), 6.*
Prostration of strength, 1, 7.
Greatly prostrated, and could speak only in a whisper (after one hour and a half), 29.
Seemed strong until she tried to get up, then was not able to stand, was obliged to be raised up at last to vomit; was left very weak and prostrated, which passed off gradually, 27.
Feeling a lassitude and indisposition to move (second day), 16.
In the evening a feeling of general lassitude has existed since 12 o'clock (fourth day), 11a.
Feeling of lassitude, with the headache (first night), 18.
Dread of movement, 19. [530.]
Toward evening we were confined to our beds, and the whole family were alarmed, thinking we would die (after a few hours), 17.
Great muscular debility and lassitude, with desire to lie down (after three hours); muscular weakness increasing (after three hours and three-quarters); debility and trembling on motion increased (after five hours), 16.
Sore and somewhat stiffened (second day), 13.*
Feel sore all over, from head to foot, at 7 A.M . (second day), 18.*
Feeling of soreness in the muscles (third day), 19.*
Throbbing sensation throughout the whole system, 28.
The pains shoot inwards and upwards, 4.
The pains are sometimes followed by itching and burning, 4.
Transitory pains, 4.
The pains all partake of the nature of neuralgia; they are pressing and shooting, sometimes sore, drawing, and aching; the pains are all made worse by motion and by pressure, 4. [540.]
Sticking-stinging pains in various parts, but always in the extremities, and from without inwards, and near the surface (after four days), 11a.
We find the symptoms predominating in the right side of the head and neck, the right upper extremity, the right side of the chest, and the right lower extremity, 4.
When a pain occurred it came with its full force at once, and so continued till it ceased, and then was followed by drowsiness and stupor, and even full sleep, 19.
Many of the symptoms are attended with heat, 4.
All the symptoms took place in from twenty to thirty minutes after nausea was first felt, 5.
In the above extract there are forty symptoms located on the right side, and thirty-one on the left. In several instances the symptoms appeared on the left side first, and either passed over to the right, or the next symptom occurred on the right side, 4.
All the symptoms worse on motion and in the open air, except the headache, which was relieved in the open air (after three hours and three-quarters), 16.
All the symptoms, except the pain in the bowels, somewhat aggravated, at 11 A.M.; most of the symptoms begin to subside at 10 P.M. (second day), 18.
All symptoms relieved while lying down, except the scraping and excoriation of the throat, and the expectoration of tenacious saliva (after five hours), 16.
All the symptoms relieved by eating, especially those in the throat (second day), 16. [550.]
The pain was less when in the open air, 14.

SKIN

Surface shrunken and of a leaden color, 5.
She was covered from the crown of the head to the soles of her feet with an eruption the like of which I never beheld; it began on the scalp and spread downwards to the very toe-nails; it consisted of erythematous blotches of irregular shape, slightly elevated, of a pale-red or pink color, very sore and painful, itching slightly only on desquamation, but too sore to allow any scratching for relief, and terminating in a dark-red or purple spot, taking about thirty days for each to pass through its various stages of eruption and desquamation, and about the same length of time to advance from the head to the feet, so that the eruption could be seen at one time in all its stages of development; there was no accompanying fever, no swelling. After Merc. Sol., 3d. x trit., which relieved the sleeplessness, and finally also the pains, the eruption grew worse rather than better, and even invaded the conjunctiva and mucous membrane of the nose and mouth; and now, after a lapse of three months, it is in the fauces and œsophagus, having entirely disappeared from the external surface, 21.
Eruption on the upper lip, left side, 4.
Eruption of spots on the chest of the size of lentils, elevated, with great itching, 4.
Pustule behind the right ear, 4.
A small boil behind the right ear, 4.
A painful boil on the left side of the neck, 4.
Suppuration of a tumor behind the right ear, with a discharge of matter and blood, 4, 8.
Suppuration of painless tumors, 4. [560.]
Drawing in cicatrices, 4.
On the third day after taking the medicine an itching commenced on his hands and feet, and spread over the entire body; four hours after this began a rash showed itself, following the same course that the itching did; with this the itching started with renewed force, and became so severe that he could hardly contain himself; the more he scratched the worse the itching grew; skin hot and dry; it seemed as if he would burn up; great desire to pour cold water on himself, which would relieve him for a few moments, but was always worse afterwards; he could not lie in bed, as the heat of the bed was more than he could bear, it aggravated the itching so badly; his skin was very red, and if he exercised, so as to feel the least warm, little vesicles could be discerned under the cuticle, 28.
Itching on the left leg, on the calf, which afterwards appeared also on the right leg, and was accompanied in the latter part of the time with a lichen-looking eruption; the itching lasted two or three weeks, and was always worse in the first part of the night, often hindering me from falling asleep until midnight, 11b.

SLEEP

Sleepiness.
Yawning, 4.
Frequent gaping in the daytime, 4.
Drowsiness, 4.
Sleepiness, 4 ; (after one hour and a half), 29.
We all passed a restless night (first night), 17.
Sleeplessness.
Restless through the night, with pains in the knees, arms, and chest (first night), 18.
Sleep restless and disturbed, during the first half of the night, by scraping and tickling in the throat, which occasioned a frequent disposition to cough, 16. [570.]
Very restless, though suffering no pain; could not get to sleep until late (third night); much nervous restlessness; after waking could not get to sleep again for a long time (fourth night), 11.
Restless sleep at night; he lies on his stomach, 4.
Very wakeful at night, 4.

FEVER

Chilliness.
Chilliness (after five hours), 20.
During the night, after the nausea, etc., had passed away, external chilliness, with perspiration; putting the hand outside of the clothes sends a shiver over him; coldness and internal shivering in stomach and bowels during the pains, even though these parts felt hot to him externally, 23.
Coldness, 19.
Great coldness (after one hour), 6.
Great coldness and withered appearance of the extremities; they felt like the hands and feet of the dead, 19.
During the whole of the sickness, from first to last, the patients complained of a sense of coldness, 5.
The whole body was cold; some shivering, but not so much as the general coldness would warrant, 19. [580.]
The temperature of the surface of the body appeared greatly below the natural standard, without moisture, 5.
Skin cold, somewhat bluish (after one hour and a half), 6, 29.
Coldness in the head, 4, 19.
Extremities cold, towards evening (after a few hours), 17.
Coldness of the feet, with increase of the capillary circulation about the face and head, 4.
Heat.
Towards morning became very feverish and thirsty, with burning all over, but more particularly in the bottom of the feet, which seemed bloated like puff balls, although they were not hot to the hand, 27.
Alternately very hot, then very cold hands and feet, 28.
Some fever (first night), 17.
Heat in the head, with slight dizziness and nausea (after three hours, third day), 18.
Heat in the head, 4. [590.]
Heat in the face, after dinner, 4.
Heat on the left side of the face, in the afternoon, 4.
Heat, with redness of the face and a sensation of fulness about the head, and coldness of the feet, 4.
No fever or heat anywhere except in face and head, 27.
Sweat.
Profuse sweat and great sensation of coldness accompanied the vomit and purging, 24.
Free sweating of the feet, most under the toes, 4.
Cool perspiration, especially on the forehead and hands (after three hours), 16.
Cool perspiration on the forehead, with the dull, pressing pain in the forehead (after one hour and a quarter), 16.

CONDITIONS

Aggravation.
( Morning ), 7 A.M., pain in temple and forehead; swelling of eyelids; symptoms of eyes and eyelids; dryness of the palate; secretion of saliva; sore throat; swelling of soft palate; dryness of throat; dryness of fauces; dryness in pharynx; on waking, pressure in stomach; symptoms of stomach, throat, and mouth; before daylight, pain in right hypochondrium; diarrhœa; pain in spermatic cods; dryness in trachea; 7 A.M., pain in lungs; stiffness of neck and back; 4 o'clock, pain in dorsum of right foot.
( Forenoon ), Heaviness or weight in the head; headache; while riding, sensation as of a plug in throat; 11 A.M., pain in back of neck and spinal column; the symptoms.
( Afternoon ), 3 P.M., pressure in head, pressure around eyes; on swallowing, dryness and soreness of throat; a gurgling sensation in parotid gland; abdominal symptoms; heaviness in lower extremities; symptoms of lower extremities; heat on left side of face; heat.
( Evening ), Photophobia; on going to bed, dryness of throat; pain in left hypochondrium; sensation in trachea; while riding, pain in left side of back; general lassitude.
( Night ), Agglutination of eyelids; towards morning, thirst and feverishness; on being woke out of sleep nausea; 9.30 P.M. to 5 A.M., vomiting; pain from anus into lower part of rectum; towards morning, pain in left side; after midnight, chest symptoms; stiffness of neck; pain in right big toe; forepart, itching; restless sleep; chilliness; toward morning, feverishness ( Open air ), Rheumatic pain in right knee; the symptoms.
( Bending shoulder backwards ), Pain in right side of chest.
( Contracting part ), Pain in trapezius muscle.
( After dinner ), Aching pain about forehead; pains in forehead; pressure in forehead; heat in face.
( After eating ), Hunger.
( Extending arm ), Aching in right upper arm, pain and tenderness in arms.
( Gaslight ), Smarting in the internal canthi of both eyes.
( Full inspiration ), Pain in cardiac portion of stomach.
( Looking down ), Pain in head.
( Lying on right side ), Pain in chest.
( Motion ), Headache in vertex; pain in umbilical region; pain in lumbar and sacral regions; aching in right upper arm; pains.
( Odor of root ), Nausea.
( Pressure ), Pain in stomach; pain in trapezius muscle; pain in tenderness in arms; pains.
( Resting arm upon table ), Twitching and fluttering of the muscles.
( Riding ), Pain in head; obstruction of nose; pain in stomach, passing to chest.
( Rising and walking about ), Intoxicated feeling.
( Stepping from high step to ground ), Pain in top of head.
( Stooping ), Pain in head.
( When swallowing ), Pain in root of tongue; saliva, feeling as if a lump were in throat.
( Talking a long breath ), Pain in right side of chest.
( Turning head to left side ), Feeling as if a lump were in throat.
( Walking ), Pain in head; headache, with sickness of the stomach; pain in cardiac portion on stomach; pain in left hypochondriac region; pain in bowels; pain in præcordial region; pain behind scapula; rheumatic feeling in left knee; aching in legs.
( Damp weather ), Sore pain in head.
( Writing ), Rheumatic feeling in little finger of right hand.
Amelioration.
( Morning ), After rising, pressure in stomach; pain in chest.
( Afternoon ), Pain in right side of chest; chest symptoms.
( Night ), Griping.
( Open air ), Headache; flow of tears; disturbed feeling in stomach; pain.
( After breakfast ), Head symptoms.
( Black coffee ), Vomiting.
( Eating ), The symptoms.
( Eating supper ), Pain in forehead.
( Emission of flatus ), Pain in bowels.
( While lying down ), Most symptoms.
( Pressure ), Pain in left instep.

Phytolacca