Aletris farinosa
por Richard Hughes & Jabez P. Dake — A Cyclopaedia of Drug Pathogenesy
Volume I — Main text
ALETRIS.
Aletris farlnoia, L. Star.grass. Nat. Ord., Hsmudor^icict.
I. Provings, — I. Man. Took^ Nov, ird, 10 dropi of 1, at a. 30 p.tii,> and t% drops at 4. At 4.30 slight nausea with pressure lo forehead; nausea increa&cd till 6, when a meal relieved it for i h., it then retxiracd and lasted all e., sight or thought of grease causing him to ga^. At 7.30 took 40 drops^ and at % next m. 50 drops. Five m* after latter felt weight at occiput, as if it would draw head back* wards> neck not having strength to prevent it 5 at same time feeling as if sealp there were contracting from side to side* All passed off while breakfasting 30 m» Itter, At 11.30 took 65 drops, 75 at 3, and 85 at 4. Stool was harder and more difficult than usual \ and soon after last dose there was slight pain in occiput and nucha for 10 m. Nov. 5. — ^At 9 a.m. took 40 drops of tlnct. Stool as yesterday. At 10, dull, heavy headache In different regions, continuing all d.,and increasing after every dose. At % and 3.30 took 75 drops. No new symptoms, but headache muci worte. (Dr. J, W, KiNc^ Amer. Homotopathut^ March» 1885.)
X. Woman. Nov. 3rd, at 1,30 p.m., took 11 drops of j,. At 3.»o senaation a& if back would break just above wajst. At 4 took 10 drops. At 5,10 »amc pain, , a Uple higher up ; at 7 a sharp pain ran from angle of I. scapula through to L I brmt. At 7,30 took 50 drops. At 8,10 feeling as if eyelids were being pressed downwards, she could hardly raise them. Nov. 4. — At 8.30 a.m. took 50 drops, Just before dose, slight pain in occiput; and immediately afterwards great weight there. At 11,30 took 65 drops, with same result. At 3 took 75 drops, and tek pressure in forehead over eyes and queer sensation behind cars. At 4 took 85 dropii. At 4.10 heaviness in occiput, forehead feels as in a vice, with dull pain running from r, temple over eye into eyeball. Soon after dinner, dull aching in hypogastrium and
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acroM back of hips» No stool since taking drug till S this e., then hard, scanty and difficult, followecl by urinar)^ tenesmus for^ h» (usually has two or three stools daily). Nov. 5, — At 9 a.m., 30 drops of tinct. In 30 m. occipital heaviness, feeling as if temples were pressed together, with occasional twinge of pain in r« temple. Took 4.5 drops at 11.30^ and 75 at x and 3.30. Soon after last ache in back of head and pressure over eyes, with sense of uneasiness for a few m. only. Urination rare while staking drug. (litU.)
- Man. Dec, 49. — At S a.m. took 35 drops of tinct., and at noon 40 drops. ' 30th. — 48 oz. oi urine passed during last 24 h,, sp. gr. 1015. Took 40 drops in m.,
30 at noon. 3jst. — Took 30 drops at m. and noon. At 6 p.m. bowels moved for first time since taking drug, stool hard, scanty ,,and difficult. All afternoon felt pain in r. side of throat, and at 5 in 1. side close up under jaw, with thirst. Dr. King examined with laryngoscope and found hyperemia of mucous membrane of both pharynx and larynx. Appetite entirely gone, has to force himself to eat. All aftcron tired and relaxed, with dull, heavy, confused feeling in head ; cannot concentrate mind for study. Jan. i, — Urine of last 14 h. amount to i> 02., sp. gr. 101a. At 8. 30 a.m. took 30 drops. At 9.30 stool as before* 2nd — Very restless during past n.; urine of 24 h. 48 oz., sp, gr. 1020, At 2,30 p.m., 30 drops. Soon after pain in 1. occiput just behind ear, for about % h. ; some short lasting pain also in
~|hroat. Frequent attempts at stool, but abortive until 10.30 p.m. 3rd.— Urine 40 oz., _ , gr. 1030. At 9 a.m., 60 drops. Almost immediately strange feeling all through
"^head, gradually settling down to dull pain in occiput^ which passed off in 10 m. 4Ui« — ^Urine 48 02., sp. gr. 1012. Took 50 drops at 8.30 a.m. At 10, stool as before, 5th. — Urine 40 oz,, sp. gr, 1022, At 9.45 a.m., 65 drops. Stool rather easier. Took 60 drops at 2.30 and 4.30, and 65 at 6 p.m. Soon after last dose pain in centre of nucha, running off into I. shoulder, continuing there 30 m. Pain m neck then moved up into occiput^ where it continued all e., till he fell asleep. At 7*30 intermittent pain in r. ant. pillar of fauces, like electric shocks, slow but strong, aggravated by any movement of head putting muscles on stretch. Inspection showed hyperemia as before. For last 3 d. has had soreness inside tip of nose. 6th. — tfnne 42 oz., sp. gr. 1030. At 9 a.m., 65 drops. Stool thin and diarrhceic, with
^hard lumps in it. After three doses of 60 drops each griping in abdomen for i h. "Took 60 drops more in e. All d. headache on vertex, much aggravated by bending [Jrwards, Nose less sore. 7th. — Urine 40 oz., sp, gr. 1024, Two doses of 60 drops to.day. Headache continued^ aggravated by difficult stool. Nose nearly well. «th, — Urine 44 oz,, sp. gr 1022. Stool hard, but expulsion easy. Vertex headache i before. 9th. — Stool to-day natural for first time since taking drug. Throughout proving, and up to 15th, lay awake till 12 or i, sleep then restless till late inm., when " became calm.* {IbidJ)
4, Woman. Jan. ist. — So drops of dnct, md.— Urine 54 oz., sp. gr, loaa* Took So drops. 3rd, — Urine 50 oz., sp, gr. 1022. At 9,30 a.m., 60 drops. At .,25 p.m., pain commenced at pubes, ran down 1. labium and then shot upwards^
liveiging to I., coming out near umbilicus. Pain was as of a knife-thrust j lasted 1 m. only. (When commencing to prove drug, a prohise yellow and mat-odorous leucorrhoea was present, having existed for years, and increased during last two months i on and d, diM:hargc was much less, and on 3rd almost imperceptible.) 4ih, — Urine 64 oz., sp. gr. 1020 j phosphates slightly increased. Took 60 drops, 5th. — Took 65, 60, and 60 drops between 9 and 4. At 4.30 heaviness on vertex and in forehead over tyt%. Much flatulence after food (quite unusual) to-day and sterday. In e. 65 and 60 drops between 6 and 8. Between 8.30 and 9.30 several paroxysms of pain, tearing or cutting, in hypogaatrium and r, thigh, lasting a — 5 m., once so sudden and severe as to make her cry out. 6th. — On rising deathly ** gone"* feeling in stomach. Urine 64 oz., sp. gr, 1020. Took five doses of 65 or 60 drops each during d. Ever since taking drug has had profuse watery discharge from nose, without other indications of coryza. At 2.30 compressive pain in temples ; at 4 sharp pain in r. shoulder, running down arm and chest to above nipple, lasting 10 m. ; at 4.15 dull pain in vertex and great weight fn occiput ; at 4.30 pain behind r, ear
• This prover had suffered for years from pain after stool, beginning in i^ — x h., and lasting 3 — ^4 h. After bcgiiming to take drug he had no pain, nor liad any ecurrcd when he reported on Jan. 31st.
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running down stMuo* mastoid. At 5.40 severe cramp-like pain in each groiiij lasting 5 m., accompanied with tccling that she roust hurry to closet, but stool was perfcctly natural j tor 40 m, dull aching in groins occasionally running down thighs, and roost intent in knee.joint«». In jo m, after last dose (7 p.m.) sharp pain in groins, continuing all e. All afternoon and c. abdomen ast it filled with wind, moving from place to place, and causing pain, which i^ relieved by passing it. Soreness felt inside nose for 2 d., r. side worst. On inspection a small crack was found inside r. nostril. 7th. — Sleep greatly disturbed by troubled dreams. '* Gone " feeling again on rising* relieved by food. Urine 64 or., sp. gr. loio. Took 60 drops at 10.30 a,m* At }t dull pain over r. cj-e, running into ball, relieved by closing eye, at same time nausea and dull pain in lower abdomen j at 11.30 pain as of a knife-stab in 1. breast for 2 m. Since xnd d, of proving there has been an eruption across chest and upper back, itching intolerably, relief from rubbing, but aggravation from scratching with nails. It appeared a simple papillary rash with much hyperemia (and hypcRBSthesia) of surrounding integument. 1 ith. — Every m. since discontmumg drug has had headache, with " gone '* feeling at stomach relieved by food. Until 11th (since ylii) unable to sleep till late, then terrible dreams on falling asleep, wakening her, until late in m. On a5th catamenia, Bcanty, but more paink&s than for years past,* (Ibid.)
5, Man proved fluid extract. On Jan. 13th took 60 drops; on t4th, dodrops at 8.30 a.m., and 65 drops at 11.30, At it.45 sharp lancinating pain in r. eyeball, lasting about 10 m. At 11,30 took Jj : about 5 m. later cramps all through abdonieti, continuing some 30 m. At 4 took 5j : soon after pain all through abdomen, settling down into hypogastrium, relieved temporarily by passing Aatus, permanently by scanty loose stool at 6.30. At 7,30 again 5J ; and in 10 m. same pains, aggravated by bending forwards, relieved by bending backwards; in 10 m* more whole intestine* seemed sunk down into hypogastrium and being cut by knives. After 10 m. scanty loose stool relieved pain. »5th. — 26 oz. of urine passed during last 24 h,, sp. gr. 1026, At 9 a.m. took 5j. In forenoon mind confused and wandering, much effort required to concentrate thoughts. Pain since rising till 3.30 p.m. in abdomen, cKtcfly hypogastrium, by spelU, at last relieved by very scanty loose stool, with and after which was much tenesmus and feeling as if anus was closed. 16th. — Ytisterday and to-day nose sore just inside tip to 1. Since taking drug faeces and flatus highly offensive. For last three nights could not sleep till very late, and then sleep was restless till late in m. This continued , with dcsultorincss of thoughts, till 22nd, {Ibid,)
- Woman proved same. On Jan. 13th, » p.m., took 60 drops. At 1.35 heavy weight in occiput, with dull pain over eyes and through temples. At 9,30 felt as if about to faint, with nausea. 14th, 9 a.m., 60 drops. At noon fore part of head felt as if in vice. At 12.30 took 60 drops, with same result. At 1 took Jj. At 2.45, pain running in 1 m, from back of car down ste mo- mast old, leaving it sore to touch. At 4 trxjk 5j. At 7 sharp pain for 1 m, in 1. breast, then through into back near angle of r. scapula. At 7.30 again 5J. At 8.5 returning of food eaten at 5.50, with burning in throat. At 9.30 pain from ant. sup. spinous process of ilium to pubes, with feeling as if diarrhoea would come on, which did not occur. 15th. — ^At 4 a«in. same pain tor 5 m., then aching down legs to feet, and up back, finally settling across back of hips ; felt there on rising at 7.45, when she felt very tired, and had also pain and heaviness in occiput, with sharp pain down r. trapezius, aggravated by bending forward, and Wf 'vtrsd. All passed off, save headache, at 8. Passed 43 oz. of urine in 24 h,, sp.gr. 1020, At 9 took ^j' All that n» pain running down thighs, worse in knees, causing her to toss about in bed and preventing sleep. On rising pain ran as before from ilium to pubes (she has this at periods). In afternoon, when sitting, annoying pain in knees. Since taking drug nights, especially fore pari, have been very restless. A dull, heavy bearinF down in hypogastrium all this d. On 1 7th courses came, painlessly for first time in life j they were true to time, but scarcely h al f th e i r usu al q uant i t y . ( Ibid.)
^ The hypogastric symptoms of this prover were familiar to her during her catamenia.
Volume IV — Appendix
ALETRIS.
(See vol. i, p. a 10.)
I. — 7. a. MisiiDB NoRMANDiE,Jan. aand, took 10 gr. of istrit.^h. before break* fiast. No immediate symptoms, but languor and exhaustion all d., with sliebt back. ache in dorsal region. 6 — 7 p.m., extrepiities cold j head and face hot and flushed}
temp. 99.1 i puUc 76 (normal), I — 9, chilU passed ; face flushed ; ears feel asti 0[ through from one to other; head dull; cannot study. i)rd. — Very restleis all n . woke unrefrcshed ; deaf in 1, ear; feels stuffed; backache continued ; headache all d. i dull and oppressed. 4 p.m., r. leg below knee feels paralysed and numls^ cannot bear weight on it (continued 2 h.). 7, feverish, pulse 81 ; temp. 99 appetite; headache increased ; pulse irregular and intermittent ; thirst during feve-»-. 14th. — Restless all n.; early stool, quite painful, a p.m., another stool, with cola 6, another stool, same character, loo^e and offensive. a5th, awoke well, save Hor sore throat, which passed off during d.
b. aSth. — Feels quite well ; but menstruation has begun, which is always of 6 d. duration and painless. Took 3 gr. of crude substance at n. 29th.— Restless all n.; woke with headache and slight pain in uterine region. Menses, usually free and bright on and d., have nearly ceased ; are dark, almost black, and of sour odour. No dysmenorrhoca, but general malaise. 30th, — Restless all n., with many dreams, Menstruating slightly till e. 3ist.^-Small urgent stool, dark and offensive, cautinr excoriation. At noon, another stool ; and at 4 another, with more pain, and fblkywM by exhaustion. At 8 another stool, but normal Lip dry and cracked all d. Thb last continued Feb. ist, but otherwise she fek as well as usual.
e. 7th. — In her normal state, repeated 3 gr. dose of substance, ^ h. before bmk. fast. Taite of drug caused nausea, which coffee increased. Felt worn out inil tired during d. 7 p.m., slight fever, face burns ; temp. 98°, pulse 100 ; very thirsty; mind clear and active. 8th. — An accouchement at n. allowed her only 1 h. tlt(^; from this she woke with headache all over and faintness, could not eat, puUe?^, eyes heavy. P.m., backache with dragging in sacral region and leucorrhcea, suiiig]' and colourless (never had this before), gth, — Same exhausted feeling; cougb 00 waking, tickling, short, dry, hard, then — increasing — became spasmodic but Dot painful, increased by talking, better out of doors; it forces urine out. Felt well otherwise. Henceforward to i6th she coughed almost incessantly, like whoopingcough ; lost her breath with it and became cyanotic ; complete inability to retain urine during it. No other symptom. On i8th cough, which had been abating lut s d., ceased as suddenly as it began on occurrence of menses 8 d. before time (she was regular to the day). Flow was light-coloured, attended by colic and bearing down pains. It contmued only 51 h., and was followed by leucorrhoea, white and stringy, till tist; with, on aoth, general malaise, and (though cough had ceased) still incontinence of urine, especially when walking fast or sneezing. On aist fek well as usual (Ibid., p. 157.)