Picric acid (Carbazotic acid), a trinitrophenol.

Formula, C6H3

(NO2 )3 .OH

Preparation , Solutions in alcohol (or triturations).

Authorities.

1 , Parisel, Thèse, Paris, 1868, took three pills, each containing 1/10 grm. of P. acid, and half an hour later took two more; 2 , same, proving on a man by a dose of 5 grms; 3 , same, proving on a woman with a dose of 4 grms; (Nos.

4 to 10 , L. B. Couch's provings, N. Y. Journ. of Hom., 2, 149, 1874.); 4 , Lance, took one dose of 30th cent. dil. on first, fourth, and seventh days; 4 a , same, another proving, one dose of 30th; 5 , L. B. C., took 30th dil. first day, two doses of 10th dil. third day, a dose of 30th fourth and sixth days; 6 , Sullivan, took a dose of 5th dil. first day, a dose of 30th dil. fourth day; 6 a , same, subsequent proving, a dose of 30th dil.; 6 b , same, subsequent took 30th dil. first, third, and fifth days; 7 , W. S. F., took 30th four days in succession, without result, then a dose of 1st cent. dil. in morning of first, third, and fifth days; 8 , J. E. T., having taken the 30th, 15th, and 5th, without result, took the 1st on the first, third, fifth, eighth, eleventh, twelfth, and fourteenth days; 9 , Anderson, took 30th first and second days, without symptoms, then took the 25th on third day; 9 a , same, took same dose once; 9 b , same, three weeks later, took 2d cent. on first and second days; 10 , Gallup, took a dose of 5th dil.; 10 a , same, repeated; 11 , T. F. Allen, proving on a man, aged thirty-five, took one dose of 30th on first, second, third, seventh, and eighth days; 12 , same, an unmarried woman, aged twenty-six, took 30th on first, second, fourth, fifth, seventh, ninth, tenth, and thirty-sixth days; 12 a , same, subsequent proving, a dose of 30th dil. first, three doses second, one on the third and fourth days; 13 , Dr. John S. Linsley, MS. to Editor, proving with a dose of 30th, subsequently repeated; (Nos.

14 to 18 , provings by Prof. S. A. Jones, MS. forwarded for this work.); 14 , J. O. Garmon, aged thirty-two, weight 172, took 10 drops of 2d dec. dil., 2 A.M., first day; 12 drops, 9 A.M., second day, 20 drops third and fourth days, 16 drops fifth day, 25 drops sixth day, 30 drops seventh day, 25 drops eighth day, 20 drops ninth, tenth, and eleventh days; 15 , J. A. Baker, took 10 drops of 1st dec. dil. morning of first, second, third, fourth, and fifth days, 15 drops sixth day, 10 drops seventh day, 15 drops eighth, ninth, and tenth days; same, three times, eleventh day; 20 drops, three times, twelfth day; 25 drops 9 A.M., 30 drops 1 P.M., and 20 drops 6 P.M., thirteenth day; 16 , J. D. Baker, aged thirty-seven, took 10 drops of 1st dec. dil. daily for ten days, same twelfth day, 20 drops thirteenth and fourteenth days; 17 , E. E. Adams, took repeated doses of 1st dec. dil. for sixteen days (usually four doses a day), 10 to 40-drop doses; 18 , Geo. A. Taber, aged twenty-three, took 1st dec. dil., 8 P.M., first day; 10 P.M., second day; at 12 M., 2 and 3 P.M., and 20 drops at 4 P.M., third day; 18 a , same, twenty-five days after last dose took 20 drops at 9 P.M., first day; 20 drops of 2d dec. dil. 8 A.M., and several times during the day pellets saturated with the 1st dec. dil., second day; pellets of 1st third and fourth days, two powders of 1st dec. trit. eighth and ninth days; 18 b , same, took 3d trit., 10 grains, 7 and 9 P.M., first day; 6.30 A.M., second day; 10 grains 2d dec. trit. 3, 6, and 9 P.M., second day, and 6.45, 9.30, and 11 A.M., third day; 10 grains 1st dec. trit. at 2.15, 4, and 9 P.M., third day; 20 grains 10.15 A.M., 10 grains at 3 and 6 P.M., fourth day, and 1 P.M., fifth day; 20 grains 4.45, fifth day; 30 grains 7.45 A.M., 4.45 P.M., sixth day; 20 grains 8.30 A.M., seventh day; 40 grains 10.15 A.M., eighth day; 20 grains at 9 and 11 A.M., ninth day, and at 10 A.M., tenth day.

MIND

While enjoying the society of gentlemen, the idea of marriage seemed unendurable, 12a.
Low spirits (second and twelfth days), 15.
A great desire to be alone (eleventh day), 16.
Very irritable (after third dose, thirteenth day), 15.
Great indifference and lassitude (fourth day), 9a.
Great indifference; lack of will-power to undertake anything (fourth day), 9.*
Disinclination for mental or physical work; desire to sit still; aversion to talking or movement, with the headache (second day); dulness and indifference; disinclination to talk and study; takes no interest in surrounding things (third day), 10.
Can't collect thoughts at all or study (fifth day), 4.
During the day could not keep my thoughts to study; I could read for a little time, then my mind would seem to be played out (sixth day), 13a. [10.]
Prostration of mind after writing for a time (eighth day), 18b.

HEAD

Vertigo.
At 6 P.M. vertigo, with nausea, on least motion; at 9 P.M., vertigo and nausea , with the intense pain in frontal region and vertex; could not sit up; greatly aggravated by even raising the head (second day), 6a.
Vertigo worse, in the evening (thirteenth day), 17.
Vertigo, on stooping or bending of the head and on lying down (eleventh day), 17.
Dizziness and vertigo, lasting half an hour, worse when rising up from sitting position, at 12 M. (thirteenth day), 8.
General Head.
Head felt congested (eleventh day), 17.
Sensation of fulness and heaviness of the head, with disinclination for mental or physical work, at 12 noon; fulness and heaviness increased until 2 P.M., when it developed into a severe throbbing headache; worse on the left side, but chiefly in the left eye and occipital region markedly aggravated by going upstairs, which causes an intense throbbing pain in the eyeball; headache relieved at 4 P.M. (second day); fulness and heaviness of the head, followed by throbbing pains in the eye and occiput (left), but not as marked as before (third day), 10.
Heavy (fulness) dull pressing pain in the head, as if full of blood (after nine hours), 4a.
Fulness and heaviness of the head, with disinclination to do anything (after four hours); headache increases, and finally develops into an intense throbbing pain in left side of the head, chiefly in the eyeball and forehead, and extending backwards to occipital region; better from keeping quiet; worse from motion, and greatly aggravated by going upstairs, 10a.
Heaviness of the head, alternating with a sensation of emptiness (after half an hour), 1. [20.]
Head feels heavy (first, second, and third days), 15.
Head feels dull and heavy (after seven hours, twelfth day), 8 ; (third day), 11.
Dull heavy feeling in the head (third day), 6a.
Head feels as if falling forward (after four hours, fifth day), 7.
Headache of a heavy blinding dizzy character, with great fulness; head feels as if it would burst open; head feels as if too small; pains mostly in the vertex and frontal regions; stooping aggravates the pains, and causes vertigo; headache comes on at 9 A.M., and steadily increases until I go to bed; scalp sensitive to touch; sore aching in infraorbital region (after one hour, fifth day), 6b.
Dull general headache (seventh day), 14.
Dull headache; could not get to sleep until 2 o'clock, after going to bed at 9 (tenth day), 16.
Dull heavy headache, lasting all day, coming first on the right side, then spreading to the left (ninth day), 8.
Slight dull headache (ninth day), 14.
A peculiar dull continuous pain all over the head; aggravated by motion, turning the head, and stooping; relieved by lateral pressure upon the head (after seven hours and a half, fourth day), 6. [30.]
Dull pain diffused throughout the head (sixth day), 14.
Severe headache all day, aggravated on rising, better in open air (eleventh day), 16.
Headache, which he never before had, was one of the most marked symptoms, 7.
Head, much worse, in the evening; cannot study (sixth day); head somewhat affected, in the evening (seventh day), 16.
Headache, with trembling, afternoon and evening (ninth day); headache, in the evening (tenth day), 15.
Headache (after first dose, twelfth day); continued (after third dose, twelfth day), 15.
Headache, with heat in the head (after first dose, thirteenth day), 15.
Headache slight, in the morning, probably in consequence of oversleeping (thirty-ninth day), 12.
Slight headache more or less all day, confined to the upper part of anterior and middle lobes of brain, also above the eyes; the character of the pain is dull, with an occasional shoot of pain (ninth day), 17.
Not much headache in the forenoon; more severe in the afternoon (fourteenth day), 17. [40.]
Slight headache for two days after taking the medicine, 17.
At 8 P.M. full pressing sensation in the head, from within outwards, as if the head would by apart; greatly aggravated by motion and by study (second day), 6.
At 9 P.M. severe pressing pains in the head, laterally, from within outwards, with sensation as if the frontal bones would split open; aggravated by turning the head, moving the eyes, or from the least motion (second day), 6.
Pains generally about the head, relieved by pressure (after ten hours), 4a.
Felt well before taking the drug, but in a short time pain came in head, an exact repetition of previous symptoms (eighth day), 11.
Do not feel able to study on account of pain in head (third day), 15.
All the head pains ceased by bandaging the head tightly (fifth day), 4.
Heavy throbbing pains in the head, extending from behind the ears forward to the supraorbital notch, and thence downward into the eye, with the great soreness and lameness, especially on left side (fifth day), 4.
Burning along the coronal suture (after second dose, twelfth day), 15.
Head symptoms continued for several days after discontinuance of drug, 15.
Forehead. [50.]
Dull headache in the front and right side of head, with heat in head and upper part of body (after two hours); in the evening pain in the head, with some thirst and heat, chiefly in the temples, and burning sensation in external ears (first day), 16.
At 7 P.M. dull steady frontal headache (with vertigo when rising and when walking), (second day), 6.
Dull heavy pain in frontal region, extending to the vertex, worse from motion, at 10 A.M.; at 1 P.M. headache worse, aggravated by the least motion, stooping, bowing the head, or rolling the eyes; at 5 P.M. intense pressing headache, as before (second day), 6a.
Intense pain in frontal region and vertex, with vertigo and nausea, at 9 P.M. (second day), 6a.
Dull sleepy pain in the forehead, with sour eructations (lasting an hour), at 3 P.M. (second day), 7.
Dull heavy frontal headache, with great heaviness and weakness in small of back and limbs (fourth day), 5.
Slight frontal headache, with sickness at the stomach, as from a weight (third day), 8.
Headache confined to front part of head; shoots from outside to centre, quite severe, lasting all the evening (twelfth day), 17.
In thirty minutes a dull pain in forehead and temples, worse on the right side (first, second, and third days); headache not so severe (sixth day), 15.
Slight frontal headache, extending to vertex, of a dull heavy tingling character, all of the evening (second day), 17. [60.]
Same kind of headache as usual in superior part of anterior lobes of brain (after third dose, third day), 17.
Headache in anterior and superior part of head, lasting all the evening (eighth day), 17.
Headache confined to back part of anterior and top of middle lobes of brain; pain dull, with an occasional throb (eleventh day), 17.
Temples.
Beating of temporal arteries (first, second, third, twelfth, and thirteenth days), 13.
A disagreeable dull headache, severest over right temple, passing around occiput (after four hours, second day), 14.
Dull sleepy pain over left temple (after nine hours, fifth day), 7.
Sharp and severe pain in right temple, running to back of head (after twenty minutes); soon after it appeared in left temple, extending to suboccipital region; these pains lasted but a short time (first day). Same pains as yesterday, but more severe in left temple; lasted about an hour (after fifteen minutes, second day). Pain in left temple, sharp and neuralgic in character, disappearing in left and going to right temple; it alternated between the two temples, and was more severe than on the two preceding days (after five minutes, third day), 11.
Severe sharp intermitting pain in the left temple (after ten hours, sixth day), 5.
Sharp cutting pain in left temple, over a small transverse branch of the temporal artery (second day), 7.
The pains of the head have been changeable, alternating between right and left temple, sometimes occurring in centre of forehead (third to seventh day), 11. [70.]
The pains in the temples increased, and also the pain in the forehead; all these pains extended to the back of the neck (after twenty minutes, seventh day), 11.
All pains very severe, especially a pain in right temple, which extends over the eyebrow to the inner angle of right eye (after four hours, seventh day), 11.
Slight dull and throbbing pain in right temple (after thirty minutes, first day, and after one hour, second day), 14.
Pressing headache between the temples (after second dose, eleventh day); headache increased (after third dose, eleventh day), 13.
Formication over right temporal region, running up over parietal bone (after two hours and a half, first day, and after one hour, second day), 14.
Vertex.
Full heavy feeling in the vertex, at 8 A.M. (second day), 6b.
Full feeling on top of head (tenth day), 12.
Full heavy headache in the vertex, worse when stooping and moving eyes (after four hours and a half, third day), 6b.
Slight headache in top of head, soon after taking medicine (tenth day); same pain in vertex (eleventh day), 17.
The usual headache to-day more severe, in the afternoon (fifteenth day), 17. [80.]
More headache in the vertex, aggravated by studying and bending the head forward (after second dose, sixteenth day), 17.
No headache this morning, but during the night, when I awoke, I had considerable through the upper and back part of head; I have felt this several times during the day (sixteenth day), 17.
Headache, throbbing on top of head, aggravated by turning to lie on back, with the nausea (tenth day), 12.
Slight twinges of pain on top of head, at 9 P.M. (thirty-ninth day), 12.
About 11 A.M. pain in vertex, with slight fever (second day), 16.
Parietals and Occiput.
Felt a slight dart of pain on right side of head, about the middle of the afternoon (fourteenth day), 17.
Headache, mostly in right side, with occasionally a shooting pain through the temples from right to left side (seventh day), 14.
Pain in the right side of the head, running behind the ear (after two hours and a quarter), 14.
Contracted or squeezed sensation of left hemisphere of brain on going into open air, at 6.30 P.M. (second day), 9a.
Dull pain in right lower occipital region, beginning at 11.15 A.M. and lasting till 12.30 P.M.; the pain came on gradually and as gradually subsided (third day), 18. [90.]
Pain in right lower occipital region, at 8 P.M., lasting about an hour, and at the same time a sensation as of a band passing along the right parietal eminence (fourth day), 18b.
At 9.15 A.M. dull pain in right lower occipital region, which comes and goes at short intervals (fifth day), 18b.
At 1 P.M. pain in lower right occipital region, coming on at intervals since 11 A.M. (eighth day), 18b.
A dull pain began in right lower occipital region at 8 A.M. and continued two hours (ninth day); beginning about 4 P.M. and lasting until 10 P.M. (eighteenth day), 18b.
Dull heavy throbbing and burning pains, commencing in occiput and extending forward to supraorbital foramen, and thence down into the eyes, which throb and feel sore to the touch (after ten hours), 4a.
Pain in lower right occipital region again comes on, lasting about an hour (fourth day), 18a.
At 6 P.M. pain in lower right occipital region, as though right side of cerebellum was loose; keeps throbbing; worse on walking; better while sitting quiet; passes off in about an hour (fourth day), 18a.
In the evening, pain in the right and lower part of occiput (eighth day), 18a.
Pain in right side and lower part of occiput, coming on about 4 P.M., finally extends upwards over towards the right supraorbital region, continuing about three hours (ninth day), 18a.
In the afternoon, pain for a few minutes in right and lower side of occiput (tenth day), 18a. [100.]
In the afternoon, pain in right and lower side of occiput (fourteenth day), 18a.
Pain in lower and right side of occiput, in the evening; did not last more than half an hour (nineteenth day), 18a.
Heavy pain in occipital region, extending down the neck and spine (after nine hours), 4a.
Pain in back of head and neck (third day), 11.

EYE

Bright yellow color of the sclerotic, skin, and urine (second morning), 1.
Eyes to-day markedly yellow, being stained by the acid (seventh day), 18b.
Yesterday I observed a slight dryness of my eyes, and a slight tingling or smarting, worse by constant use and lamplight. This morning there was some thick acrid matter in the corners of my eyes, worse by constant use and lamplight (ninth day); eyes smart and are dry, same acrid mucus in corners (tenth day), 17.
On waking, and for an hour afterwards, eyes felt as though there were sticks in them; inflammation of eyes has partly subsided (eighteenth day); felt all the evening as though there were sticks in them (twentieth day), 18a.
Sensation as if sand was in the eyes, with smarting pain and acrid tears (fourth day), 7.
Eyes feel dry, as if full of sand (seventh day), 12. [110.]
Eyes have felt throughout the proving as if dry, and inner surface of lids feel rough (tenth day), 12.
Awoke with sharp stinging pains in both eyes, at 7 A.M. (sixth day), 7.
Eyes feel sore (tenth day), 16.
Eyes feel worse on moving them, or turning them upwards (fifth day), 4.
Gaslight hurts the eyes (after ten hours), 4a.
Orbit.
Pressure over both eyes, worse from studying and motion, better from sitting still (after eleven hours, eleventh day), 8.
Pain over right eye in supraorbital region, sharp and vibrating, stopping a moment or so, and beginning again (lasted half an hour), (after five hours), 7.
Dull pain in the supraorbital region, coming from the occiput (after four hours), worse from movement and stooping (second day), 8.
Dull, heavy headache in supraorbital region, as before (after six hours, eighth day), 8.
Slight pain in supraorbital region and in the back of the neck (after three hours and a half), 5. [120.]
Severe aching pain in the left supraorbital notch, at 6 P.M. (eighth day), 5.
Head feels disagreeable and sore, especially the supraorbital region, at 5 P.M. (second day), 6a.
Dull pain in supraorbital region (sixth day), 8.
Supraorbital and frontal headache, more or less all day (thirteenth day), 17.
Throbbing over the right eye (after four hours, seventh day), 11.
Lids.
Lids sore and slightly swollen (third day), 6b.
Styes, with soreness and swelling of lids (fifth day), 6b.
Margins of lids very red on waking (thirty-ninth day), 12.
Agglutination of eyelids, on waking, in the morning; had to "pick my eyes open" (seventeenth day), 18a.
Great heaviness of the lids; can't keep them open (fifth day), 4. [130.]
Heat in upper eyelids, with increased flow of lachrymal secretion (after second dose, thirteenth day), 15.
In the evening, heaviness of eyelids, with a little burning in the eyes (sixteenth day), 18a.
Heaviness of the lids (after ten hours), 4a.
Lachrymation.
Lachrymation (fifth day), 4 ; (after ten hours), 4a.
Eyes watery; stinging pain in them (after four hours, fifth day), 7.
Conjunctiva.
Conjunctivitis (fifth day), 4.
Conjunctiva injected (after ten hours), 4.
Conjunctivæ greatly inflamed, right eye is the worst; hard work to keep eyes open; makes eyes feel sticky to read; eyes better from washing in cold water and in cold air, worse in warm room (seventeenth day), 18a.
Ball.
Aching pain in the eyeballs, which feel sore; worse by moving them; better by closing them and keeping quiet (second day), 6a.
Eyeballs sore to touch, with photophobia (third day), 6b. [140.]
Severe, sharp, shooting pain in centre of the eye, extending back to occipital region; pain seemed to follow the course of the optic nerve (third day), 6b.
Sore, painful sensation in the eyeball; pains in the eyes aggravated by strong light, and by turning the eye; cannot bear to look at a bright light (fifth day), 6b.
Heavy, pressing, smarting, and burning pains in the eyeball, relieved by pressure (after ten hours), 4a.
A shooting pain from right eyeball to right side of occiput, lasting but a few seconds (after ten minutes), 18b.
Pupil.
Dilated pupils (fifth and seventh days), 4 ; (after ten hours), 4a ; (fifth day), 6b.
Vision.
Sight dim and confused (tenth day), 16.
Have to bring objects close to the eyes to see them; seem to be looking through a veil; can see to read clearly only at one point, about five inches from the eyes (after ten hours), 4a.
While reading, sight is blurred, seemingly caused by winking mucus over the pupils (sixteenth day), 18a.
Everything seems blurred, as if looking through a fog or a thick veil; can read only with book about five inches from the eyes (fifth and seventh days), 4.
Air looks smoky (sixteenth day), 18a. [150.]
Sparks before the eyes (after half an hour), 1.
Whirling of objects (after half an hour), 1.

EAR

Ears began to burn and look puffy, with a sensation as if worms were crawling on them; these symptoms lasted two hours (after six hours), 4.
Burning sensation in external ears, with the headache (first day), 16.
Pain behind the right ear, running down right side of neck (after four hours, seventh day), 11.
Buzzing and hissing in the ears (after half an hour), 1.

NOSE

Bleeding of the nose (right nostril), with heat and congestion of the head (after six hours and a half); bleeding of right nostril again (after seven hours and a half, fourteen hours), 5.
Nose filled with mucus; can breathe only through the mouth; relieved by going into open air (third and fourth days), 7.
Small furuncle in the left nostril, 10a.
Stinging pain in right side of nose (after four hours, seventh day), 11. [160.]
Sensation as if something were pressing greatly on the bridge of the nose (fifth day), 10a.

FACE

Tingling sensation of lips (after thirty minutes, first day, after one hour, second day), 14.
Irregular dull pain in inferior maxillary bone, with beating in molar teeth (after two hours and a quarter), 14.

MOUTH

Saliva white, frothy, and stringy; hangs in long strings to the floor (eighth day), 4.
Taste sour; bad taste in mouth (after four hours fifth day), 7.
Sour bitter taste in the mouth (third day), 7.
Bitter taste in the mouth (second day), 6a.
Bitter taste in mouth, with great thirst (twelfth day), 16.
Bad taste in mouth of gas (fourth day), 7.

THROAT

Throat sore, feels rough and scrapy on swallowing, better while eating; feeling of soreness only felt on empty deglutition (eighteenth day), 18a . [Took a dose of Cocculus 30/x to-day, for throat.] [170.]
Throat sore, worse on the left side, a rough scrapy sensation on swallowing; better after eating, worse after sleep (seventeenth day), 18a.
Sore throat; disagreeable sensation back of an above soft palate, at 10 A.M. (second day); still continues with great debility (third day), 9a.
Throat feels raw, scraped, stiff, and hot, as if burnt; throat red; collection of thick white mucus on tonsils; great difficulty in swallowing, with sensation as if throat would split open (eighth day), 4.
Raw feeling in the left side of the throat, extending from behind forward to the submaxillary gland; worse when swallowing (second day), 6a.
Rough, raw, scraped sensation in the throat (left side), (second day), 6b.
A feeling as though a plug were in the throat, while swallowing saliva, also immediately after swallowing (fifth day), 18a.
Throat dry and husky (fourth day), 7.
Sensation as if something was in lower part of œsophagus (second day), 4a.

STOMACH

Appetite.
Appetite increased till to-day; have no desire for any kind of food, though I eat as usual, but without relish (eighth day), 14.
Very hungry, in the evening, obliged to eat (eighth day), 12. [180.]
Appetite poor, disgust for food (eleventh day), 16.
No appetite for breakfast; could not eat anything (eighth day), 12.
No appetite (third day), 9a ; (fourth day), 9.
No appetite; disgust for food; at noon (second day), 4a.
No appetite; aversion to food (second day), 6a.
Thirst.
Great thirst, with bitter taste in mouth (twelfth day); thirst continues (thirteenth and fourteenth days), 16.
Very great thirst for cold water, which is drank in large quantities without relief (eighth day), 4.
Some thirst (eleventh day), 16.
Some thirst with the headache (first day), 16.
Eructations.
Frequent eructations (third day), 15. [190.]
Sour eructations of gas and ingesta (after eleven hours and a half, third day), 7.
Intense raising of wind (tenth day), 16.
Bitter eructations after breakfast (second day), 4a.
Nausea.
Awoke at 5 A.M., with a deathlike, faint, nauseated feeling in stomach and abdomen, aggravated on rising and moving around; went back to bed, fell asleep, and on waking a second time, experienced the same sensation as on first waking (eighth day); awoke with the nauseated feeling this morning, but not so bad as yesterday morning (ninth day), 12.
Nauseated faint feeling at epigastrium most of the time (eleventh day); occasionally throughout the day (twelfth day), 12.
Nausea, accompanied by intermittent griping pains in the epigastric region, continuing until night (second day), 10.
Nausea (second day), 4a.
Nausea followed the dry cough (after three hours and a half), 5.
After retiring, nausea, with headache (tenth day), 12.
Nausea, on retiring (eighth day), 12. [200.]
Nausea, with the vertigo (second day), 6a.
Slight nausea, for an hour or two after taking the drug (eighth day), 18b.
Sickness at the stomach, as from a weight, with slight frontal headache (third day), 8.
Waterbrash (fourth day), 7.
Stomach.
Oppressive feeling in epigastric region (first, second, third, and thirteenth days), 13.
Disagreeable pressure as of a weight in pit of stomach, desire to belch wind, with no result, seemingly powerless to do so (after two hours and a half, second day), 14.
All the morning have felt a faint feeling at epigastrium (thirteenth day), 12.
Intermittent griping pains in the epigastric region, continuing until night, accompanied the nausea (second day), 10.
A dull pain in cardiac region of stomach, while eating breakfast, at 7 A.M. (fourth day), 18b.
Sharp pain in epigastric region (after four hours and a half, third day), 14.

ABDOMEN

Umbilicus. [210.]
Shooting pain through left umbilical region, from before backward (after nine hours), 14.
During the evening, some pain in umbilical region (third day), 14.
Quite a sharp pain about umbilicus, on left side (seventh day), 14.
Stitches through the right side in region of liver; seem to be mostly in the muscles (second day), 9a.
General Abdomen.
Fulness of abdomen (after seven hours), 14.
Much flatus, in the evening (third day), 14.
Flatus during the day (eleventh day), 14.
Wind in the bowels passed up and down, not marked (sixth day), 6b.
Pass a great deal of wind from the bowels on moving (third day), 7.
Flatus, with much rumbling in abdomen (seventh day), 14. [220.]
Rumbling and much flatus (fourth day), 14.
Rumbling in the abdomen, with crampy pain and flatus (after three hours, third day), 9.
Rumbling in small intestines (after one hour), 14.
Awoke at 7 A.M., with dull, rumbling, and coliclike pains in the abdomen (sixth day), 7.
Rumbling pain in the abdomen (after four hours, fifth day), 7.
Awoke with pain in the abdomen, and strong erections (third day), 7.
Crawling-stinging pains in abdomen (fourth day), 7.
Some pain in abdomen and neck of bladder (sixth day), 14.
Pain in bowels, lasting all the forenoon, with very little headache; pain in bowels less than usual (after third dose, third day), 17.
Hypogastrium and Iliac Regions.
Occasionally, all day long in hypogastrium, a sensation of giving way (second day), 12. [230.]
A slight vacant and sore feeling in hypogastric region (first day), 12.
Slight colicky-like pain in lower part of large intestines (second day); colicky pains worse (third day), 17.
Severe pain in the left inguinal region, on walking, and aggravated by going upstairs (after eight hours), 10a.
At night (11 o'clock), an aching sharp pain in right iliac region above the ovary, sore on pressure (eighth day), 12.

RECTUM AND ANUS

Sharp pain shooting around the anus, at 9 P.M. (thirty-ninth day), 12.
Stinging and itching at the anus during and after defecation (second day), 5.

STOOL

Diarrhœa.
Diarrhœic stool, with burning and smarting at the anus (fifth day), 6b.
Four thin stools, with great prostration, 3.
Stool twice before 9 A.M., like gruel, slightly yellow or yellowish-gray (third day), 17.
Stool rather copious, oily, yellowish (after one hour); repeated (after two hours); again (after two hours and three-quarters), 1. [240.]
Stools loose, light-colored, with cutting and smarting at the anus, during and after defecating (second day), 4a.
Stools light-colored, and passed with much burning and smarting in the anus, continuing an hour afterwards (eighth day), 4.
Soft, light-colored stool, passed with much straining (sixth day); soft stool, with tenesmus (tenth day), 8.
Scanty, soft stool, with burning at the anus, at 3 P.M. (second day), 6.
Small, ineffectual, soft stool, followed by drawing up of the anus, and accompanied by some tenesmus (third day), 9b.
Stools shoot away in soft plugs, followed by much flatus; bowels move very easily (after eight hours, second day), 41.
For sometime had been quite constipated, but now have a passage every day (seventh day), 11.
Bowels continue regular, passing easily at night and morning; passages very quick, as if greased, followed by much wind; stools have a strange odor, but not disagreeable, rather a sweetish smell, as of boiling sap (seventh day), 14.
Constipation.
Bowels constipated; only one difficult passage to-day (eighth day); very much constipated in evening, no movement of bowels; pressing-down sensation in rectum, with desire for stool, but could pass nothing (ninth day); bowels regular (eleventh day), 14.

URINARY ORGANS

Bladder and Urethra.
In the evening, a sharp pain in region of bladder, worse on the right side, lasting only a few seconds (fourth day), 18a. [250.]
Some pain in region of bladder and in abdomen generally (fourth day), 14.
Burning during urinating, and after (second day), 5.
A sensation of jerking drawing in the urethra (after second dose, thirteenth day), 15.
Slight pain after micturition (twelfth day), 17.
Micturition.
During the morning more frequent micturition than usual (fifth and sixth days), 18b.
In passing urine it kept dribbling after I got through (second day), 18a.
Urine.
Urine profuse (second day); urine had become scanty (sixth day); dark-yellow, with strong odor (eighth day), 16.
Increased flow of pale urine (second day), 15.
Increased flow of urine (fifth, eleventh, and thirteenth days), 15.
Urine increased, light-colored; specific gravity, 10.23 (ninth day). Before the proving, it had given acid reaction; specific gravity, 1020, 5. [260.]
Urine profuse; color normal; very hot when passed, accompanied with burning pain in urethra (fifth day); urine passed with burning, scalding pain (seventh day), 4.
Urine increased and of a light-amber color (eighth day); increased and of a light color, at 7 P.M. (ninth day); still pale and increased (twelfth day), 8.
Urine yellow in the morning, and of an increased quantity during the day (twelfth day), 15.
Urine continued yellow for some time after discontinuance of drug, 15.
Urine dark-red, in the evening (third day), 14.
Urine dark, specific gravity, 1030; indications of sugar; the test was good with the copper solution, also by fermentation test (fourth day); very highly colored (fifth day), 14 . [As I have not been able to get such testimony from any other prover, I hold his evidence sub judice . -S. A. Jones.]
Urine dark, high-colored; specific gravity 1025 to 1028; quantity about normal; urination followed by burning (fifth day), 6b.
Urine highly colored (tenth day), 14.
Urine of a milky olive hue (thirteenth day), 17.
Urine red (after two hours), 1. [270.]
Urine light-colored and profuse, burning in the urethra, during and after urinating; urethra feels as if burnt (second day), 4a.
Urine normal in color, but much less in quantity than it has been for three months past (third day), 17.
Urine rather scanty, of a dark-yellow color (tenth day); yellow and profuse (twelfth day); very profuse (thirteenth and fourteenth days), 16.
Urine passed in the previous twenty-four hours has a heavy deposit of urates (third day), 18a.
Urine passed in the previous twenty-four hours shows urates quite abundant (seventh day), 18a.
The Laboratory Daily Record , for May 18-19, 19-20, 20-21, gives the following data for uro-hæmatin, using HNO3 test. May 18-19, color between Plates V and VI, N. and V.; May 19-20, color between Plates VI and VII; May 20-21, color between Plates VII and VIII. The actual color plates used for comparison, are those given in Thudicum, On the Pathology of the Urine , 1st edition. (Note by Dr. S. A. Jones.).

PICRICUM ACIDUM. SEXUAL ORGANS

Male.
Terrible erections, with restless sleep (first night); long-continued and violent erections, all night (fourth night); erections like h---ll; violent, strong, and long-lasting, which I thought would surely rupture the penis; followed by profuse seminal emissions (fifth night); violent erections, all night ; could not sleep for them; had to get up, walk around, and bathe the parts in cold water (eighth night); sleep broken up by violent erections, lasting all night; had to sit up (eleventh night); violent erections (twelfth night); erections, with severe pain in left testicle, as if bruised, extending up the cord as far as the external abdominal rings, at 11 A.M. (thirteenth day), 28.*
This is the fourth morning, in succession, I have awoke with an erection (sixth day), 18a.
Awoke in the night with violent erections, which cold water relieved; returned to bed, and before an hour had elapsed, was again awakened by violent erections, applied cold water, and slept the remainder of the night (I will here remark, that I had been suffering for several months with loss of sexual vigor and entire absence of venereal desire, not having had any erections for several months, but now it is the reverse, altogether too much of a good thing), (third day), 11.
Awoke with very strong erections, and pain in abdomen (third day); awoke with emission and very firm erection, which continued about ten minutes after the emission (fourth day); terrible erections, at 4 A.M. (sixth day), 7. [280.]
Great sexual desire, with emissions (fourth night); great sexual desire, with terrible erections (fifth night), 4.
Sexual desire increased; hard erections, at night; lewd dreams, with emissions (sixth night); great sexual desire, with emissions; emissions every other night (ninth day), 5.
For two weeks following, the drug marked increase of sexual desire. After a second dose, most remarkable and intense sexual excitement, which is not allowed to be gratified by any indulgence. Amorous excitement, impelling the mind to dwell on and revel in imaginary sexual pleasure. Almost constant priapism, night and day, for seven days, impelling to amorous ecstasies and mental analysis of the physiological and psychological aspect of venery, 13.
Female.
An occasional aching pain in left ovarian region (after about four hours and a half, fourth day), 12.
In the evening, twinges of pain in the left ovarian region (tenth day), 12.
Appearance of menses, which have been delayed a week (normal menstruation very regular); during the period, profuse yellowish-brown leucorrhœa (thirteenth day). Menses painful the first time in several months; a sore bruised pain in abdominal region, with a sickening sensation. (Normal menstruation profuse and protracted, of a good color, no change in character, quality, or otherwise), 12.
Excessive and voluptuous pruritus, at night, after retiring, lasting about half an hour, making me feel irritable and exasperated (usually pruritus slight after menses, never before), (twelfth day), 12.

RESPIRATORY ORGANS

Dry cough, as from dust in the throat, followed by nausea (after three hours and a half), 5.
Can get the breath only half way down (eighth day), 4.

CHEST

Chest feels tight, as if encircled by a band (after nine hours, fifth day), 7. [290.]
In the evening slight pain in left lung, which felt as though there would be a stitch if a deep inspiration was taken, but on taking one three was not (seventh day), 18a.
Numb sensation in lower part of sternum, a symptom experienced much when living in a malarious country (fourteenth day), 17.
Dull stunning pain in the chest, with twitching in the throat, at 9.30 A.M. (second day), 7.
Pain, commencing in the right side of the chest, extending across the left (after twenty minutes, seventh day), 11.
Quite sharp pain under right clavicle (after four hours, second day), 14.
(Sharp pain in both sides of chest, worse in left, had been subject to such pains for several months), (second day), 11.
Twitching of muscles over eighth and ninth ribs (left side), (eighth day), 5.
Muscles on left side, over tenth and eleventh ribs, commenced to throb and jerk, which lasted from 6 till 11 P.M. (after two hours, fourth day), 4.
Heavy throbbing pain under tenth and eleventh ribs, on left side, at 11 A.M., which lasted till noon, then changed to the region of the kidneys, and continued till 2 P.M., when they extended downwards into my legs, especially the left (second day), 4.

HEART AND PULSE

Palpitation of the heart (first, second, third days, after first dose, twelfth day, and after second dose, thirteenth day), 15. [300.]
All day long, at intervals of ten minutes, a peculiar fluttering sensation at the base of the heart; it seemed to move; it startles me for a moment, but do not think of it again until the symptom recurs; continued all evening at shorter intervals than during the day; it became very annoying (second day); a slight fluttering of the heart, in the evening (third day); fluttering at the heart (fourth day), 12a.
A slight pain at apex of heart, in the evening (tenth day), 12.
Pulse.
Pulse 70 before taking, fell to 50, when it was very feeble; in the reaction it rose to 80, 3.
Pulse 75 before taking, fell to 52, 2.
Pulse 71 (when taking the dose); 58 (after one hour and a half); 55 (after two hours); 52 (after two hours and a half); 48, small, feeble, and difficult to feel (after three hours); 60 (after ten hours); 65 (after fourteen hours); 75 (second morning), 1.
Pulse 50, weak and small (second day), 4a.
Pulse irregular (first, second, and third days), 13.

NECK AND BACK

Neck.
Terrible pains in neck and occipital region, extending forward to supra-orbital notch, and then down into eyes, the same as before (seventh day), 4.
While lying down, in afternoon, muscles on right side of neck felt as though they would give way (sixth day), 18a.
On lying down in bed, at night, muscles on right side of neck felt as though they would give out, and neck would be dislocated. (I was lying on my right side), (sixth day), 18a.
Back. [310.]
Pains, heaviness, and weakness of the muscles of the back and lower extremities (fifth day), 6b.
Pain in back (eleventh day); continues, especially when sitting (twelfth day), 16.
Pain in back while bending forwards, extending from scapula to lumbar region, on the right side (fifteenth day), 18a.
Dorsal.
Aching in the dorsal region (seventh day), 12.
Pain under right shoulder-blade, as if a sharp instrument were thrust in (after four hours, seventh day), 11.
Burning along the spine, worse from trying to study, better from motion (after third dose, twelfth day), 15.
Very hot feeling in the lower dorsal and lumbar region (first, second, and third days), 15.
Lumbar.
Heavy dull pain in the small of the back, at 6 P.M. (sixth day), 8.
Severe aching pain in the lumbar region, extending down the legs, aggravated by motion (second day), 6a.
Severe, heavy, dragging pains in the region of the kidneys and back of the neck, extending upwards and downwards until they met between the scapulæ, at 2 P.M. (fifth day), 4. [320.]
Great pain between the hips, of a dull, heavy, dragging character, which descended slowly to the left leg, with severe chills, and throbbing and jerking in muscles in different parts of the body (after two hours, fourth day), 4.
Tired sensation in lumbar region and limbs, when waking from sleep, 12 P.M. (first night), 5.
Awoke at 6 A.M., with tired and heavy sensation in small of back and limbs (third day); same, at 4 P.M., with dull, heavy, frontal headache (fourth day), 5.
Pain in lumbar region (tenth day), 16.
Shooting pain in upper left lumbar region (after nine hours), 14.
In the evening, a slight shooting pain in right side of small of back (eighth day), 18a.
Stitch in small of back on bending forward, while sitting (seventh day), 18a.
Sacral.
Quite severe pain in region of coccyx, bladder, rectum, and umbilicus, all vague and indefinite, wandering and shooting, caused by wind in the intestines (fifth day), 14.
Sharp pain, for an instant, in region of base of coccyx (after thirty minutes), 14.
Weak feeling in sacral and lumbar regions, with the excessive languor (seventh day), 12.

EXTREMITIES. [330.]

Weakness and heaviness of the limbs (third day), 6.
Heaviness and weariness of limbs, on walking a short distance (sixteenth day), 18a.
Rheumatic pains in the joints of extremities (after first dose, thirteenth day), 13.
Great heaviness in the arms and legs, especially the legs, on exertion ; legs feel weak and heavy all the time (sixth day), 5.
Great heaviness in the extremities, especially the left; legs feel as if made of lead (after ten hours), 4a.
Weakness of the extremities (fourth day), 9.
Great weakness and debility of extremities (second day), 9a.
Awoke, at 6 A.M., with tired and heavy sensation in limbs and small of back (third day); same, with dull, heavy, frontal headache, at 4 P.M. (fourth day), 5.

SUPERIOR EXTREMITIES

Shoulders feel very tired and sore, as after violent exercise (eighth day), 11.
Right shoulder feels sore and tired (after four hours, seventh day), 11. [340.]
Same sensation in both shoulders (fourth day), 9.
Deepseated pain in the right arm, at elbow-joint, between ulna and radius, continuing for several days (after four days), 9.
Shooting pain in the left arm, at elbow, extending down the arm (after eight hours, sixth day), 5.
Twitching of lower portion of biceps of left arm, lasting half an hour (after twenty-four hours); during the forenoon (third day), 10.
Shooting pains in hands (tenth day), 16.
Left hand goes to sleep, feels as if blood would stop circulating (thirteenth day), 16.

INFERIOR EXTREMITIES

Very great debility of muscular system, especially of the lower extremities, with the sore throat; unable to remain out of bed (third day), 9a.
Great weakness and heaviness of the lower limbs (ninth day), 8.
Great weakness of the muscles, especially those of the lower extremities and back (third day), 6a.
Great weakness in the lower limbs (second day), 8. [350.]
Numb sensation in the lower limbs (after five hours, fifth day), 8.
Great heaviness and weakness of the lower extremities (after eight hours), 10a.
Tired feeling in the limbs, when going upstairs (after five hours and a half), 5.
Hip.
Twitching of muscles on back of left hip, at 9 P.M. (first day), 5.
Great heaviness of the hips and legs, lasting all day (eighth day), 4.
Thigh.
Dull pain in the muscles on the anterior part of the thigh, and in lumbar region, accompanied with feeling of lassitude and weakness in the same, especially in the legs, aggravated by moving (second day), 6.
Pain in left anterior portion of thigh; can hardly flex and extend the legs, lasting fifteen minutes (after three hours, third day), 7.
Knee.
Knees feel weak (sixth day), 7.
Weakness of the legs at the knees (after four hours, fifth day), 7.
Leg.
Great weakness of legs , especially the left, which trembles (fifth day), 4.* [360.]
Legs heavy, like lead ; lifted from the floor with difficulty (left leg worse), after two hours (fourth day), 4.*
Legs felt heavy and very weak; also great weakness in the region of the hips (second day), 4.*
Great heaviness of both legs , at 9 P.M. (sixth day), 7.*
Legs dull, heavy, weak, and moved with difficulty (fifth day), 5.
Numb sleepy pain in the legs, extending to the bottoms of the feet, relieved by cold water and open air (sixth day), 7.
Legs (anterior or extensor muscles) feel numb (second day), 9a.
Legs feel tired and sore, as after a long journey (seventh day), 11.
Calves of both legs feel lame and sore (twelfth day), 8.
Legs, below the knees, feel very sore and tender to the touch (second day), 4.
Legs and small of back sensitive to pressure (second day), 6a. [370.]
Twitching of flesh between knee and ankle of right leg (eighth day), 11.
Deep-seated sore pain, almost unbearable, in upper part of Scarpa's triangle of left leg; not relieved by pressure, cold, or warmth; worse at night, absent during sleep, and coming on on awaking, for several days (after four days), 9.
Severe pain in back portion of left leg, extending to the sole of the foot, with sensation as if foot would go to sleep, relieved by motion and open air (third day), 7.
Pain in the calves of the legs, lasting all night (eighth night), 8.
Severe pain in the anterior portion of the leg, when touched (second day), 4.
Four or five times, during the afternoon, a dull pain would come in calf of right leg, occupying a space about the size of a silver half dollar; it would last but a few seconds, then an interval of relief, followed by a return of the pain (fifth day); pain occupying the same space as yesterday; the spot feels a little sore on hard pressure (sixth day), 18b.
Pricking sensation, as from needles, in the legs and feet (after four hours, tenth day), 8.
Feet and Toes.
Feet feel as if frostbitten (after seven hours, twelfth day), 8.
Numbness in the left foot (after eleven hours, eighth day), 8.
Crawling pain in the sole of the left foot and under the patella (fourth day), 7. [380.]
In afternoon and evening, soreness in ball of big toe on left foot, which passes off with continued walking (fourth day), 18a.

GENERALITIES

Veins sunken and small, especially on the left side (fifth day), 4.
(A general feeling of wellbeing, a renewed vigor, in the morning, and an ability to rise much earlier than usual), 21.
Trembling of all the muscles (sixth day), 15.
Great trembling of the muscles (after second dose, thirteenth day), 15.
General debility (after second dose, thirteenth day), 15.
Weakness of muscles (fourth day), 9a.
*Tired feeling (second day), 15.
At 7 in the evening, while walking a tired feeling came over me, as though I had made some great exertion; it seemed as though my strength was all gone; legs felt heavy and could hardly go another step; feet unusually tired all the evening (third day), 18a.
Get very tired on the least exertion (fourth day), 18a.* [390.]
On taking a short walk, in the afternoon, find that I am more than usually tired (fifth day), 18a.
Lame and tired sensations all over the body (sixth day), 7.*
Very tired, lame, and weak sensation, when arising from bed (eighth day), 4.
Very tired on going upstairs (sixth day), 5.
On walking down town, am more tired than common (seventeenth day), 18a.
Awoke at 6 A.M., feeling tired and unrefreshed (fifth and seventh days); awoke at daybreak, feeling tired and heavy (ninth day), 5.
General dull feeling (tenth day), 14.
*General sense of lassitude (after four hours), 8.
The excessive languor began to return and unfitted me for my daily work, so I discontinued the medicine (fourth day), 12a.
Disagreeable feeling generally; lassitude (eighth day), 14. [400.]
Excessive languor throughout the day (the weather may, however, account for that), (fifth day); with a weak feeling in sacral and lumbar regions (seventh day), 12.
Excessive languor (tenth day), 12.*
Very languid, feel better when out of doors (eighth day), 12.
Languor most of the time, for past two weeks (thirty-sixth day), 12.
Languid; no desire to talk or do anything; indifferent to everything around me ; sleepy, and want to lie down (third day), 11.*
Great prostration, so that he was obliged to lie down; it seemed difficult to move the limbs , but without anxiety and with profound quiet (after three hours), 1.*
Great prostration on walking, in afternoon and evening (ninth day), 18a.
Great prostration, on walking or making the least exertion (fourteenth day), 18a.
Great prostration, on walking (fifteenth day), 18a.
Prostration; need of repose after a short walk (second morning), 1. [410.]
Prostration, on slight exertion (sixth day), 18b.
At 1 P.M., a prostrate feeling came over me, while walking a short distance, which was quite unnatural to me (fifth day), 18b.
I had a peculiar nervous symptom which I never have, except when a fever is leaving me. I felt as if I was about to be crushed by the bedclothes; arms, face, tongue, and forepart of brain seemed to reach to the clouds when I was going to sleep (sixteenth day), 17.
Great soreness and lameness, especially on left side, when rising, in the morning, accompanied by heavy throbbing pains in the head, extending from behind the ears forward to the supraorbital notch, and thence downward into the eye, with burning-throbbing pains and dilated pupils, conjunctivitis, and lachrymation (fifth day), 4.
Felt a numbness of the whole body, with pains, as felt when taking a cold (tenth day), 16.
Throbbing and jerking in muscles in different parts of the body, with the severe chills, and great pain between the hips (after two hours, fourth day), 4.
Rheumatic stitches in different parts of the body, with great muscular debility (second day), 9a.
All pains worse in left side (seventh day), 11.
Pain in right side (tenth day), 16.
Every hour in the day darting pains in various parts of the body, extending into the bones (eighth day), 4. [420.]
All pains lasted till 8 P.M. (fifth day), 4.
The symptoms of the head, eyes, legs, and of fever, grew worse until after 2 P.M. (fifth day), 4.
The symptoms lasted till 7 P.M., when they commenced to ameliorate (second day), 4.
Aggravation, between 10 A.M. and 2 P.M., 10a.
Aggravation, between 11 A.M. and 2 P.M. (second day), 4a.
All pains relieved by sitting, still, and aggravated by the least motion, and from getting up; symptoms lasted till 11 P.M. (fourth day), 4.
Better in the afternoon, and from motion; worse again in the evening (first, second, and third days), 15.
All symptoms relieved by cold water, and walking in the open air (fourth day), 7.
Symptoms not so marked, in the open air (sixteenth day), 17.
Scarcely any symptoms, when at rest (eleventh day), 17.

SKIN. [430.]

Yellow color of the skin persisted for nine days, 3.
Yellow color of the skin, lasting for a week, 2.
Small, painful, reddish elevations like furuncles around the mouth and face; when opened they exude a thin clear serum, which soon dries into a transparent scab; they then become pustular, and very painful, and contain a thick, opaque pus, like condensed milk (eighth day), 4.
Small, reddish elevations, resembling furuncles, on the face, which become pustular, and are accompanied by burning, stinging pains when touched (ninth day), 5.
Have had pimples on the face and neck for several years before taking the drug. On the next day after last dose I noticed they were remarkably increased in number and size, 18.
A sensation as though the skin was drawn tight over the epigastrium (eighth day), 18a.
Itching of body during night (sixth day), 16.

SLEEP

Sleepiness.
Drowsiness; slept an hour this afternoon, after which I felt better (after second dose, thirteenth day), 15.
Gaping quite frequently while in church (fifth day), 18a.
Can't keep the eyes open in studying (after four hours); very sleepy; can't keep my eyes open, at 9 P.M. (eighth day); very sleepy and tired, at 9 P.M. (after seven hours, twelfth day), 8. [440.]
In the evening great sleepiness, which was relieved by walking in the open air (thirteenth day), 18a.
Sleep sound, but unrefreshing (second day), 5.
Sleeplessness.
Could not get to sleep last night for a long time, from ideas crowding upon the mind (ninth day), 18a.
Sleep very restless, until 12 (fourth, fifth, and seventh nights), 4.
Sleep restless, until 11 P.M. (fourth day); till about midnight (sixth day); restless and tossing, till 12 (eighth night), 5.
Sleep restless, with terrible erections (first night); sleep restless (fifth and twelfth nights); sleeplessness all night (fourteenth night), 8.
Sleep restless, tossing until 12, then fell into a heavy restless sleep; awoke unrefreshed (after ten hours), 4a.
Awoke this morning an hour earlier than usual, and dozed until time to get up (seven), (ninth day), 14a.
Awoke at 3 A.M., and found it difficult to go to sleep (seventh day), 16.
Dreams.
Was dreaming constantly during the night, dreamed I was pregnant (fifth night), 16a. [450.]
Dreaming all night (fourteenth night), 8.

FEVER

Chilliness.
Severe chills, with the pains between the hips, and with the throbbing and jerking in different muscles (after two hours, fourth day), 4.
Extremities cold (after ten hours), 4.
Cold extremities decidedly marked throughout the whole proving, 9b.
Coldness of the hands and feet (fifth day), 6b.
Great coldness of the feet (after two hours, fourth day), 4.
Heat.
Fever; great chilliness; can't get warm; followed by cold, clammy sweat; chilliness predominates (second day), 4a.
Slight fever (tenth day), 16.
Slight fever, with the pain in vertex (second day), 16.
Heat in head (first, second, and third days), 15. [460.]
Head feels hot (after twenty minutes, seventh day), 11.
Heat and congestion of the head, with the nosebleed (after six hours and a half), 5.
Forehead hot (after seven hours and a half, fourth day), 6.
Great heat in the right side of head (after second dose, thirteenth day), 15.
Heat in lower dorsal and lumbar regions (after second dose, thirteenth day), 15.
Sweat.
Profuse perspiration, 3.
Profuse cold clammy sweats, with great chilliness (fifth day), 4.
Cold clammy sweat of feet, in evening (seventeenth day); feet cold and sweaty all day (eighteenth day); cold clammy perspiration in the evening (twentieth day), 18a.
Cold clammy sweat of hands and feet, in daytime (thirteenth day), 18a.
Cold clammy sweat of hands (fourteenth day); in the forenoon (sixteenth day), 18a.

CONDITIONS

Aggravation.
( Morning ), 8 A.M., headache in vertex; on waking margins of lips red; agglutination of eyelids; on waking, nausea; faint feeling at epigastrium; while eating breakfast, dull pain in cardiac region; on waking, pains abdomen; 6 A.M., awoke with tired, heavy sensation in small of back and limbs; on awaking, pain in legs; renewed vigor; on awaking, tired feeling; on rising, soreness and lameness of left side.
( Forenoon ), 9.30 A.M., pain in chest, 10 A.M. to 2 P.M., the symptoms; cold clammy sweat of hands.
( Noon ), On rising up from sitting position, vertigo.
( Afternoon ), Headache; 5 P.M. pressive headache; 3 P.M., pain in forehead; headache in vertex; pain in right and lower side of occiput; 6 P.M., pain in left supraorbital notch; pain in small of back; 2 P.M., pains in region of kidneys and back of neck; 4 P.M., tired heavy sensation in small of back; pain in calf of right leg.
( Evening ), Vertigo; head symptoms; 7 P.M., frontal headache and vertigo; 9 P.M. pain in frontal region and vertex; 6.30 P.M., on going into open air, contracted sensation of left hemisphere of brain; heaviness of eyelids; 9 P.M., pain around anus; pain in left lung; 6 till 11 P.M., throbbing in muscles of left side; pain at apex of heart; 9 P.M., twitching of muscles on back of left hip; heaviness of legs; symptoms; 9 P.M., sleepiness.
( Night ), 12 P.M., on waking from sleep, tired sensation in lumbar region; pain in leg; itching of body; until 12 P.M., sleep restless.
( Banding head tightly ), Pains.
( Binding head ), Vertigo; headache in vertex; stitch in small of back.
( While bending forward ), Pain in back.
( Bowing the head ), Headache.
( On exertion ), Heaviness in arms and legs.
( During and after defecation ), Stinging and itching in anus.
( Going upstairs ), Headache; pain in left inguinal region; tired feeling in the limbs; tired feeling.
( Lamp light ), Pain in eyes.
( Strong light ), Pain in eyeballs.
( Lying down ), Vertigo.
( During and after micturition ), Burning.
( Motion ), Pressive sensation in head; dull pain over head; pain in frontal region; headache in frontal region; headache in left side of head; pressure over eyes; pain in supraorbital region; pain in lumbar region; the symptoms.
( Moving ), Wind from bowels; pain in muscles of thighs.
( Moving eyes ), Pressive pain in head; headache in vertex; eye symptoms; pain in eyeballs.
( Raising head ), Vertigo. ( Rising ), Vertigo; headache.
( Rising and moving about ), Nausea.
( Rolling the eyes ), Headache.
( Warm room ), Eye symptoms.
( After sleep ), Sore throat.
( Stooping ), Vertigo; pains in head; dull pain over head; headache; headache in vertex; pain in supraorbital region.
( Studying ), Pressive sensation in head; headache in vertex; pressure over eyes; burning along spine.
( Swallowing ), Raw feeling in throat; feeling as if a plug was in throat; throat rough and scrapy.
( Touch ), Pain in pimples on face; pain in anterior portion of leg.
( Turning eyes ), Pain in eyeballs; eye symptoms.
( Turning head ), Dull pain over head; pressive pains in head.
( Turning over ), Headache on top of head.
( Constant use of eyes ), Pain in eyes.
( When walking ), Vertigo; pain in lower right occipital region; pain in left inguinal region; heaviness and weariness of limbs; tired feeling; prostration.
( After writing ), Prostration of mind.
Amelioration.
( Afternoon ), The symptoms.
( Evening ), 7 P.M., the symptoms.
( Open air ), Headache; mucus in nose; sleepiness in legs; pain in legs; languor.
( Walking in open air ), The symptoms; sleepiness.
( In cold air ), Eye symptoms.
( Closing eyes ), Pain in eyeballs.
( While eating ), Sore throat.
( Keeping quiet ), Headache in left side of head.
( Motion ), Burning along spine; pain in legs; the symptoms.
( Pressure ), Pain about head; pain in eyeballs.
( Lateral pressure upon head ), Dull pain over head.
( Sitting still ), Pain in lower right occipital region; pressure over eyes; the symptoms.
( Continued walking ), Soreness in ball of big toe.
( Cold water ), Eye symptoms; erections; sleepiness in legs; the symptoms.

Picricum Acidum