Neutral Acetate of Copper, C2H3 CuO3 + Aq. The symptoms here included, from various kinds of food cooked in copper vessels, belong to the acetate, subacetate, carbonate, and some organic salts of copper, the action of all of which is nearly or quite identical.

Preparation , Triturations.

Authorities.

1 , Fabas, Journ. de Méd., XVI, 228, poisoning by verdigris, from Hahnemann's Cuprum; 2 , Hamburg Mag., VIII, 442, poisoning by verdigris, from ibid.; 3 , Lauzonus, Misc. Nat. Cur., Dec., III, case 7 to 8, obs., 10, from verdigris, ibid.; 4 , Orfila, Toxicologie, cases of poisoning by verdigris, ibid.; 5 , Percival, Med. Trans, III, 8, from eating coppery pickle, ibid.; 6 , Pet. de Abbano, De Venen., c. 16, effect of verdigris, ibid.; 7 , Pyl, Samml., VIII, 90, poisoning by verdigris, ibid.; 8 , Ramsay, Med. Obs. and Enq., from verdigris in food, ibid.; 9 , Zwinger, Act. Helvet., V, 252, from verdigris, ibid.; 10 , Drouard, Expér. et Obs., Sur l'empoison. par l'oxide de Cuivre, Diss. de Paris, 1802, effects of swallowing about a drachm of Egyptian salve (vert de gris, honey, and vinegar), from Wibmer; 11 , Pyl, Samml., van Aufs., a. d. Staats-arzk., Vol. VIII, poisoning of a girl aged 24, by 4 ounces of vert de gris, Wibmer, same case as number 7; 12 , Duval, Diss. sur la Toxicol., 1806, poisoning of a man by vert de gris, Wibmer; 13 , same, poisoning of a soldier by 1 1/2 ounces, Wibmer; 14 , Reveillé Parise, Gaz. de Santé, 1820, poisoning of a man aged 29, by a large dose, Wibmer; 15 , Albert, Henke's Zeit. f. d. Staats, 1832, poisoning of a family from eating sausages poisoned by V., Wibmer; 16 , Rhodius, Obs. Cent., III, Obs., 95, a gardener poisoned by fishes cooked with salt and oil in copper vessels, Wibmer; 17 , Strack, Journ. de Med.-Chir., etc., t. 24, 1766, poisoning of four children from beans cooked in copper, Wibmer; 18 , Navier, Contre-poisons de l'ars., du subl. cord., du Vert de gris, etc., Paris, 1777, a girl aged 18, poisoned by butter from a copper spoon, Wibmer; 19 , Jeanroy, Mem. de la Soc. Roy. de Méd., 1778, poisoning of a family by meat cooked in copper, Wibmer; 20 , Fahner, Beit. Zar. pr. cud. Ger. Heilk., 1, 297, a girl aged 18, poisoned by beans cooked in copper, Wibmer; 21 , Marizot-Deslandes, from Drouard's Diss., a woman poisoned by fish cooked with vinegar in copper, Wibmer; 22 , Langenbeck, Deutsche Klinik, 1851, thirty-one persons poisoned by food cooked in fat which had become green from remaining two days in copper vessels, Fr. Mag., 4, 859; 23 , Renauldin, Journ. Univ. Med., 1820, a man aged 24 swallowed 3 or 4 grains of verdigris in coffee, Fr. Mag., 4, 511; 24 , Wittcke, Med. Zeit. v. Ver. Preuss., 1838, a man aged 30, took half an ounce of V., Fr. Mag., 1, 44; 25 , Beer, five cases of poisoning by candies colored with copper, from Orfila's Toxicology; 26 , Orfila, a man aged 44, took half an ounce of verdigris; 27 , same, poisoning by food cooked in copper; 28 , Frank, Journ. de Med., 1755, a lady and four daughters by milk soup cooked in copper (Hempel's Mat. Med., II, 249); 29 , Munneke Archiv. f. Hom., 15, 3, 109; persons poisoned by broth cooked in copper; 30 , Escolar, L'Union, 1854, poisoning of an apothecary by pounding verdigris (Herschel's Archiv., 2, 81); 31 , Reinhardt and Henke, a man took 3 ounces for suicid, from the same; 32 , Davidson, Med. Facts and Obs., London, 1792, p. 61, eight persons poisoned by soup served with a copper ladle greened by long exposure to the air; 33 , Clapton, Clin. Soc. Trans., Lond., 1870, a sailor drank lemon-juice which had stood in a copper kettle; 34 , Corrigan, Dubl. Hosp. Gaz., 1854, poisoning of a man by handling verdigris; 35 , Armstrong, five persons poisoned by pudding containing verdigris, Med. Times, 1844 (from Berridge's collection, suppl. to B. J. of Hom., 1874); 36 , Journ. de Chim. Méd., 1854, four persons poisoned by verdigris in soup (Berridge's coll.); 37 , Boggs, lady poisoned by an injection from a brass syringe covered with verdigris, Berridge, from Lancet, 1869; 38 , Fothergill, poisoning by water from a spring impregnated with copper, Berridge, from "Caution to Heads of Families," 1790; 39 , Journ. Gén. de Méd., 1827, sixteen persons poisoned by milk from a goat that had eaten sour soup from a copper vessel (goat died), (Berridge's coll.); 40 , The Chemist, men poisoned by wine from copper vessels, Berridge's co ll.; 41 , Journ. de Connais., 1843, a woman poisoned by verdigris; 42 , Reinhardt, Henke's Zeit., 1854 (Band F. M. Ch. Rev.), a man poisoning by 1 1/2 ounces; 43 , Moore, Lond. Med. Gaz., 44, p. 487, poisoning of Hindoos on shipboard by verdigris; 44 , La Chinque (Lond. Med. Gaz., 4, 155), poisoning by vinegar in which copper coin had been steeped; 45 , Chevallier, Le Cuivre, etc., p. 20, poisoning of four persons by grape-jelly containing acetate of copper; 46 , Pritchard, Lond. Med. Gaz., 11, 211, effects of milk cooked in copper; 47 , Journ. Gén. de Méd. (from Med.-Chir. Rev., 1, 158), poisoning by peas that had stood in copper vessels; 48 , Taylor, Guy's Hosp. Rep., 1866, poisoning of six persons by gravy cooked in copper; 49 , Croserio, Journ. de la Méd. Hom., 1, 1846, poisoning by artichokes kept in a copper vessel; 50 , Breyfogle, Med. Investigator, 8, 481, poisoning of several persons by food cooked in copper; 51 , Elb (from Hering's Cuprum), effects of Cupr, ac., accidentally taken in a large (homœopathic) dose; 52 , Degrange, Journ. de Méd. de Bordeaux (Lond. Med. Gaz., 31), fatal poisoning by the carbonate.

MIND

Emotional.
Attacks of rage frequently returning; she tried to bite the bystanders, 8.
Attacks of mania ; he fancies that he is a military officer; a fancy that he is selling green vegetables; a fancy that he is repairing old chairs. Merry singing. He spits in the faces of the attendants, and laughs heartily at it, 8.
Attacks of mania, with full, rapid, hard pulse, inflamed eyes, wild look, and disconnected talking, ending with sweat, 8.*
Attacks of surly, ill-natured mania, 8.
Delirium, 8, 13.*
Delirium furious during the first day (in only one boy), 22.
Delirium (appeared in seven of the worst cases) of a quiet kind, consisting of unintelligible murmurings, at times interrupted by lamentations, 22.
Delirium or constant sopor, in some amounting to complete coma, in others, on the contrary, to complete sleeplessness, 22.
Slight delirium, 23. [10.]
*Disconnected, delirious talking, 8.
Raving during sleep (second day), 29.
Talks all the time (third day), 49.*
Taciturnity (second day), 44.
*Crying like a child, 8.
Frequent crying out, 14.
Their look is confused, but they are in full possession of their mental faculties, and their speech is easy and perfectly rational. Nevertheless they are still liable to these paroxysms of howling, which always come unexpectedly, 28.
Anxiety, 15, 21 , etc.
Great anxiety (soon after), 41 ; (third day), 49.*
*Great anxiety, with unusual tossing about the bed, 29. [20.]
That anxiety peculiar to pain in the stomach, 4.
Apprehensiveness, 17.
Loss of sensitiveness, and moping in a corner, .

HEAD

Confusion and Vertigo.
*Great confusion of the head, 22. [30.]
Great confusion of the head, with beating pains in it (second day), 29.
Vertigo, 22, 25, 29.
Vertigo, even to falling down if she arose from bed; this was especially distressing when she was obliged to rise on account of her bowels, 29.
Vertigo , a very marked and persistent symptom, mostly violent; it usually outlasted all the other symptoms, though it was generally relieved by the evacuations of the bowels; it was always combined with a certain degree of stupefaction, 22.
Vertigo, so violent that the patient is unable to sit up in bed, 22.
Spinning vertigo, 51.
Reeling from side to side, increasing so that patients were obliged at last to go to bed, 22.
General Head.
The head is drawn obliquely, 8.
The head is drawn backward, 4.
Violent congestion to the head, 29. [40.]
Dulness and headache, 8.
Heaviness of the head, 22 ; (third day), 49 , etc.
Head heavy and pained (second day), 41.
Feeling of heaviness in the head, 26.
Pain in the head (after half an hour), 42.
Most violent pains in the head, chest, and abdomen, 29.
Pains in the head, becoming more and more intolerable (two cases), 45.
Compressive pain in different parts of the head (third day), 49.
Headache, 25 ; (after twenty-five hours); (after forty-two hours), 45 , etc.
Headache in nearly all cases; in severe cases very violent, especially in the forehead and vertex, becoming less after one or two days, sometimes, however, returning, 22. [50.]
Headache in the evening, .

EYE

Objective.
Red inflamed eyes, with a wild look (during the delirium), 8.
Brilliant eyes (soon), 41. [70.]
Sparkling eyes (soon after), 41.
Staring, sunken eyes, 8.
Eyes prominent (second day), 41.
Eyes sunken, 26.
Eyes sunken and dim, 22.
Eyes sunken, deeply seated, surrounded by blue rings, 4.
Fixed eyes, 8.
Eyes fixed upward, 52.
Brow.
Severe pain over eyes (after half an hour), 42.
Lids.
Eyelids very red and swollen, so that they could hardly be opened (third day), 49.
Conjunctiva. [80.]
Conjunctiva yellow, of a greenish hue, 30.
White of the eye somewhat red (second day), 29.
Conjunctiva of eyes bloodshot, 43.
Pupil.
Pupils dilated, 22 ; (second day), 44.
Pupils always very much dilated, but sensitive to light, 22.
Pupils contracted (second day), 29.
Pupils contracted in only three cases (out of thirty-one) in which there was much congestion of the head during the first days, 22.
Vision.
Photophobia (second day), 29.
Eyes cannot tolerate the lamp-light, 29.
Frequent blackness before the eyes, flickering and vision of sparks, 22.

EAR. [90.]

Difficult hearing, 26.
Slight deafness, 4.
Complete deafness, in a girl of 22, 22.
Roaring and ringing in the ears (second day), 29.
Roaring and ringing in the ears, in some cases continuing a long time, and associated with difficult hearing, which only gradually disappeared during convalescence, 22.

NOSE

Nose red and swollen (third day), 49.
Very violent fluent coryza, with lachrymation and smarting in the eyes (third day), 49.
Epistaxis (fifth day), 41.
Profuse epistaxis, with petechiæ, in a child, twenty-four hours before death, 22.

FACE

Objective.
Countenance heavy (second day), 41. [100.]
Features sad, depressed, 4.
He was a miserable-looking man, 33.
Face expressed the greatest anxiety, 14.
Countenance expressive of pain (soon), 41.
Face expressive of great pain, 24.
Paleness (second day), 44.
Pale face, 17, 52 ; (third day), 41.
Face pale, collapsed, 22.
Face pale, with expression of the greatest prostration, or even of complete stupidity, 22.
Jaundice, with quiet expression, 4. [110.]
Jaundice appeared on the second day, was still worse on the third, with vomiting and eructations, sensation of heaviness in the head, difficult hearing, grayish stools, great thirst, dark turbid urine, with yellowish sediment; jaundice disappeared after about two weeks, 26.
Face and eyelids red (second day), 41.
Face, in some cases, red and turgid, during the first days, 22.
Face in one case red, in the others pale, 25.
Face very red and swollen (third day), 49.
Face flushed (second day), 41.
Features altered, full of anxiety, 4.
Swelling of face (soon after), 41.
Face and eyelids swollen and red (second day), 41.
Face puffy, red, hot, 29. [120.]
Sunken face, 22.
Face sunken, yellow, 30.
Features distorted (from larger quantities), 43.
Spasmodic distortion of the face, 8.
Face at times spasmodically distorted, when the eyes seemed staring and retracted in the orbits, 29.
Lips.
Lips swollen (third day), 41.
Chin.

MOUTH

Gums.
Gums ulcerated (third day), 41.
Tongue. [130.]
Tongue swollen and pale, 46.
Tongue rather white (second day), 49.
White furred tongue, 5.
Tongue at first coated white or yellowish, moist; in worse cases the margins became red, after one or two days, while the back remained pale, or the whole tongue seemed red with enlarged papillæ, but moist; in the worst cases it became very red and dry, the papillæ very prominent, giving the tongue a rough look; when the disease was at its height it was cracked and brownish; in other cases the epithelium came off on the eighth day, and the whole mucous membrane of the mouth was loosened in large flakes; in another case on the sixth day some roundish ulcers with a yellow base appeared at the tip and on the margins, 22.
Tongue green, 23.
Tongue greenish, 30.
Tongue, in several cases, red, in other moist, and covered with a whitish or yellow fur, 22.
Tongue furred and clammy, 43.
Tongue moist and flabby, 33 . or yellowish fur, 22.
Tongue, in mild cases, moist and pale, or only red on the margins, but in most cases, red, dry, rough, with enlarged papillæ, 22. [140.]
Tongue dry, 29.
Tongue and throat affected, as well as the mucous membrane of the mouth (second day), 41.
General Mouth.
Dryness of the mouth, 25.
Dryness of the mouth and throat, 29.
Mouth dry (second day), 49.
Dry mouth, without thirst (third day), 49.
Pretty sharp pain in mouth and pharynx, 45.
Saliva accumulating, and flowing from mouth, 51.
Saliva.
Much viscid saliva (third day), 41.
Saliva accumulating, and flowing from mouth, 51.
Accumulation of water in the mouth, .

THROAT

Objective.
Inflammation of the throat, preventing swallowing, 4.
Swelling of throat (second day), 41. [160.]
Throat very much swollen (second day), 41.
Throat hard and swollen; could not swallow; in course of day, the difficulty of deglutition had increased so much that the patient did not wish to swallow any more (second day), 41.
Spasm of the throat, which prevents speaking, 4.
Dryness of the throat, with thirst, 3.
Burning sensation in throat (after twelve hours), (one case), 48.
Burning heat in throat (soon), 41.
Sense of constriction in throat, 37, 45.
Pressive pain in the throat, 29.
Pricking sensations in throat, 36.
Uvula.
Diffuse redness of the velum, with croupous exudation on the tonsils, 22. [170.]
Velum palati and posterior wall of the pharynx dark brownish-red, dry, without a trace of mucus, with great difficulty in swallowing, and rough voice, 22.
Fauces and Œsophagus.
Spotted redness of the faces, 22.
Constriction of gullet (soon), 41.
With ineffectual attempts at vomiting, they suffered from a distressing feeling of constriction in the course of the œsophagus, and across the chest, in the direction of the diaphragm, 43.*
Swallowing.
Swallowing difficult (third day), 13.
Swallowing painful, 52 ; (second day), 41.

STOMACH

Appetite.
Disinclination to eat, 52.
Loss of appetite, 22, 43.
Loss of appetite, even aversion to food, 22.
Appetite completely lost, 22. [180.]
No appetite; although stomach felt empty, as if wanting food (third day), 49.
Anorexia, 26.
A very great desire for acids; they want nothing else, for several days, 50.
Thirst.
Thirst, 10, 13 , etc.
Great thirst, 22, 26, 51.
Great thirst for cold water, 29.
Thirst urgent, 37, 43.
Intense thirst, 45.
Severe thirst (after twelve hours), (one case), 48.
Violent thirst, 24. [190.]
Very violent thirst, 26, 29.
Extremely violent thirst, 4.
Unquenchable thirst, 25.
Eructations and Hiccough.
Eructations, 26.
Constant eructations, 5 . [Not found. -Hughes.]
Frequent eructations of sourish bitter water preceded by hiccough (sixth day), 29.
Frequent bitter and sourish eructations, as from heartburn, rising into the throat, so that it was spasmodically constricted, and swallowing was prevented (sixth day), 29.
Hiccough (after three hours), 44.
Hiccough, with spasmodic contractions of the pharynx, 29.
Violent hiccough (after three hours), 13. [200.]
Frequent singultus, often loud enough to be heard all over the house, the patient being unconscious, 50.
Nausea and Vomiting.

ABDOMEN

Hypochondria.
Pains in the right hypochondrium, extending to the right shoulder, on the fifth day, 22. [270.]
Left hypochondrium tender to pressure, 31 ; (after half an hour), 42.
Umbilical.
Dull pain in the umbilical region (after one hour), 23.
Violent pain in the umbilical region, 25.
Very violent pain in the umbilical region, less noticed in the epigastric region, not aggravated by pressure, 23.
General Abdomen.
Distension of abdomen (soon), 41.
Distension abdomen (second day), 13.
Abdomen distended, painful to touch, 25.
Abdomen distended, somewhat hard and painful to touch, 14.
Abdomen greatly distended, 10.
Rapid swelling of the abdomen, 4. [280.]
Abdomen tympanitic and painful on least pressure (second day), 41.
Tympanites; in one case very distressing; her abdomen becoming tense as a drum, which, however, was not very long in subsiding, 35.
Abdomen meteoric, painful to pressure, 30.
Abdomen flattened, but sensitive (second day), 41.
Abdomen contracted slightly painful to pressure, 26.
Belly contracted, hard, and very sensitive all over to the slightest pressure (second day), 44.
Retracted abdomen, 4.
Hardness of the abdomen, with great painfulness when touched, 4.
Abdomen hard, retracted (in a boy of ten years), drawn backward, almost to the spine, not sensitive to pressure, 22.
Violent spasmodic motions in the intestines and in the stomach, 3. [290.]
Chronic gastro-enteritis, 33.
Pains in the abdomen, 1, 3, 8 , etc.

RECTUM AND ANUS

Rectum so inflamed and sensitive that an enema could not be administered (second day), 41. [330.]
Sensation of heaviness and uneasiness at the rectum, after stool (third day), 49.
Smarting at the anus, after stool (third day), 49.
Frequent urging to stool, 24.
Tenesmus, after stool (third day), 49.
Constant tenesmus, 27.
Severe tenesmus, and burning sensation felt within the rectum, and close to the sphincter ani (in all cases), 43.
Violent, painful tenesmus (third day), 49.

STOOL

Diarrhœa.
Diarrhœa, 3, 12 ; (after twelve hours), 48 , etc.
Constant diarrhœa, 17.
Profuse diarrhœa; the stools continued for a long time with tenesmus and prostration, only relieved after eight days, 10. [340.]
Violent diarrhœa, 3.
Diarrhœa, slimy, mucous, brown, afterwards greenish, mixed with streaks of blood, 29.
Purging, 33.
Purging; stools copious, watery, and dark, 37.
Purging, with tenesmus, 47.
Stools very frequent (at first), 22.
Very frequent liquid stools, with a great deal of bright-red blood, and shreds of membrane, sometimes very scanty, sometimes more abundant, sometimes containing fragments of solid fæcal matter (third day), 49.
Frequent evacuations (one case), 45.
Frequent small bilious stools, with burning and tenesmus, 30.
Frequent calls to evacuate the bowels. Every half hour, or even less, sometimes in the course of twenty minutes, they were forced to go to the ship's chains; but seldom, in the attempt to relieve the bowels, was feculent matter discharged. Blood in small quantities, and slimy mucus stools tinged with blood, were passed from the rectum. Shreds of lymph and frothy ashen-colored secretions were forced from the bowels by dint of straining. Without affording relief in a single case, these discharges from the bowels aggravated the sufferings of the patient, 43. [350.]
Stools involuntary, liquid, not very copious, coming either at the commencement of the disease, or after two or three days, 22.
Profuse involuntary, liquid, green, and offensive stools (after three hours), 23.
In two cases (children) the stools were involuntary during the collapse; one bloody, the other not, 50.
Copious stools (third day), 41.
Copious stool, containing a pretty large quantity of acetate of copper (third day), 41.
Liquid stools, 25, 49.
Thin liquid stools, .

URINARY ORGANS

Micturition.
Evacuations of the bladder and bowels on the fourth day, with relief of the symptoms, 13.
Micturition every five or ten minutes; she was, however, able to pass only a little urine; the passage was attended with smarting, as from soreness in the urethra, 29.
Involuntary passage of urine, 50.
Micturition, with burning, 31.
Urine scanty, 37.
Urine scanty and scalding (second day), 44. [380.]
Retention of urine, 25.
Suppression of urine (third day), 49.
Suppression of urine and fæces (fifth day), 41.
Complete suppression of urine and fæces, 41.
Urine suppressed altogether (or retained in the bladder), 43.
Urine.
Urine high-colored and tinged with blood, 43.
Urine dark-red, turbid, with yellowish sediment, 4.
Urine usually brownish turbid, depositing a sediment (in many cases normal), 22.
Urine turbid and jumentous, 22.
Urine turbid, dark-red, with yellowish sediment, 26.

RESPIRATORY ORGANS

Cough and Expectoration. [390.]
Frequent, violent, dry cough, with tearing pain in the head; the cough was followed by violent pulsation of the heart, lasting several minutes; at this time the anxiety and pressure in the chest returned, especially while sitting; cough came on at night between 11 and 1 (sixth day), 29.*
Much expectoration (one case), 45.
Respiration.
Respiration accelerated, 23, 24.
Respiration, though rapid, was free, 52.
Breathing short (after three hours), 44.
*Difficult respiration, 45.
Dyspnœa (second day), 44.
Suffocative loss of breath, 6.*

CHEST

The chest was spasmodically constricted, whereby the respiration was impeded, increasing her already great anxiety, 29.*
In one case the vomiting was followed immediately by a succession of sharp cramping spasm in the chest, causing the young lady to scream out, 50.

HEART AND PULSE

Heart's Action. [400.]
Violent palpitation of the heart, 51.
Pulse.
Pulse quick, and at the same time so small and weak and thready as scarcely to be felt, 43.
Rapid spasmodic pulse, 15.
Pulse small, rapid, spasmodic, 24.
Pulse hard, full, and frequent (third day), 49.
Pulse moderately accelerated, soft, 22.
Pulse moderately accelerated, small and soft, 22.
Pulse in many cases not altered in frequency; in other especially towards the termination of the disease accelerated, seldom above 90, soft, becoming small and weak, 22.
Small regular pulse, about 90 a minute, 26.
Pulse from 120 to 140; small and wiry, 43. [410.]
Slow pulse, 24 to the minute, 4.
Quick and irregular pulse, 45.
Pulse small and irregular, 37.
Pulse small, irregular, at times convulsive, 19.
Pulse large, slow, and intermitting (second day), 44.
Pulse, in four cases small, contracted, and slow, in one case (a full-blooded boy) hard, full, and frequent, with red face and dry skin, 25.
Pulse hard, small, and very slow (after three hours), 44.
Pulse full and hard, 33.
Pulse hard (third day), 13.
Hard and contracted pulse (second day), 44. [420.]
Pulse contracted, 23.
Hard and contracted, 18.
Pulse small, contracted, but regular, 14.
Pulse small, weak, hard, contracted, 29.
Depressed pulse (soon), 41 ; (second day), 44.
Pulse oppressed (second day), 41.
Laboring pulse (soon after), 41.

NECK AND BACK

Lancinating pain at nape of neck, on bending head backwards (third day), 49.
Stitch in the left shoulder-blade, on moving the head (third day), 49.
Pain between the shoulders, 28. [430.]
Pain in the loins, 25.
In the loins and sacrum, at the navel and in the iliac region acute lancinating pains were complained of in each case, 43.

EXTREMITIES IN GENERAL

Objective.
Trembling of the limbs, 4, 19 , etc.
Convulsive movements of the limbs, 4, 45.
Slight convulsions in limbs (second day), 44.
Spasms of the limbs, 4.
Constant painful jerkings in the hands and feet, extending upward into the upper arm and into the legs, with cramps in the calves; this jerking very plainly alternated between the flexor and extensor tendons, 29.
Periodic spasmodic contraction of the fingers and toes, frequently so severe that the fingers could scarcely be extended by any force; these contractions were painful, 29.*
Unusual loss of power of the arms and limbs (after several day), 20.
Weakness of the limbs, 21. [440.]
A gradually increasing weakness and prostration of the limbs, 22.
Weakness and pain (aching) in the limbs for several days, 50.
Subjective.
Extremities benumbed, 43.
Pains and cramp in the extremities, 39.
Pain in the limbs as from exhaustion (third day), 23.
Pain at the elbow, in the bend of the knees, etc., with a feeling of languor in all the limbs, 28.
Cramps in the extremities, 27.
Cramps in the extremities, and convulsive movements of the limbs, 1.*
Violent drawing and tension in the limbs, frequently associated with shuddering and chilliness, though the skin was not cold, 22.*
Bruised sensation and feeling of paralysis in the extremities and small of the back, so that it was difficult to use the limbs, associated with tearing pains (fourth day), 29.

SUPERIOR EXTREMITIES

Objective. [450.]
No power to hold anything in the hand (fourth day), 29.
Subjective.
Tearing pains in the upper extremities, 25.
Hands.
Hands became numbed (after twelve hours), (one case), 48.
Fingers.
Nails white (after twelve hours), (one case), 48.

INFERIOR EXTREMITIES

Objective.
Great weakness of the legs, 30.
Remarkable weakness of the legs, 4 . (See S. 493.)
Subjective.
*Cramps in the lower extremities, especially in the calves, 25.
Thighs.
Pains in the thighs, 21.
Dull pain in the muscles of the thighs on the anterior surface, 4.
Legs.
Lies constantly with the legs drawn up, 30. [460.]
Cramps in the calves, 4, 21.
Violent cramps in the calves, 24.
As the pulse rose and they became warm, violent cramping, paroxysmally, in the calves, appeared in two cases, drawing one limbs sideways and backward, but always relieved by rubbing, 50.
Toes.
Both large toes were tetanically drawn downwards, with most violent pains in the soles of the feet, 24.

GENERAL SYMPTOMS

Objective.
Emaciation, 9.
Emaciation of a greater or less degree, in all cases, lasting a long time, and only after several months did the natural weight and healthy color return, 22.
Great loss of flesh, 34.
On venesection, the blood showed an inflammatory crust (second day), 41.
Most of the patients lay still and apathetic, looking straight ahead with dim, lustreless eyes and a stupid relaxed expression, 22.
Lying on the back, with the head bent backward, 14. [470.]
The limbs and trunk were stiff, the jaws clenched, 4.
Great trembling, especially of the hands, which incapacitated them from holding anything with safety, 35.
The whole frame seemed to writhe under the pain, 43.
Frequent twitchings at nig ("during sleep"), 8.
Convulsions, 26 ; (fifth day), 41.
Convulsions; his limbs and body were stiff, jaws clenched, 13.*
Convulsions, with constant vomiting and violent pains in the abdomen, which gradually passed into a paralysis, 7.
Convulsions (in only one case out of thirty-one, a robust woman of 47) after violent pains in the last dorsal vertebræ, which were not sensitive to pressure; the pains extended suddenly into the left arm, as far as the wrist; the arm was spasmodically flexed and extended for several minutes, followed by loss of power (with perfect sensibility), lasting several hours; these attacks returned on the two following days, gradually becoming weaker; the paralytic weakness of the arm and pain in the back disappeared on the following day, 22.
Convulsions that seemed to involve more particularly the abdomen and the upper and lower extremities; when thus attacked, they uttered a horrible cry, a sort of howl, or croaking resembling the croaking of frogs. They rose in their beds with irresistible force, so that the strongest men were unable to keep them down. They were quite crazy, looked frightened and attempted to escape; their eyes glistened and seemed to start from their sockets. They stared and looked wild. These paroxysms came so frequently that they seemed to continue without any interruption. If one was attacked, the other persons, upon hearing the cries of their companion, were likewise attacked with rage. Thus they kept up a sort of reciprocal howling. Two of these persons are even now in this sort of sympathetic state of suffering, although they occupy entirely separate rooms; as soon as one feels the attack coming on, the other is likewise affected, .

SKIN

Objective.
Skin, pale, earthy, yellowish, without a real jaundice, 22.
Skin of a light-yellow color, especially on the face and conjunctiva (third day), 49.
Skin flabby and relaxed, especially with a sunken face, 22.
Contraction of the skin of all the limbs, 4.
Eruptions.
Eruptions on the skin, 2. [530.]
Eruption seemingly of a leprous kind, consisting of spots of different sizes, the largest of which were white and scaly, with moist base, appearing as if something acrimonious had been secreted under the cuticle, with thickened, rose and separated from the cutis. It was more or less all over the body, and very much amongst the hair of the head. There was no itching and no particular pain. The quantity of eruption was in exact proportion to the amount of soup eaten (after two days), 32.
Rash on the chest and hands, 5.
Petechial spots on neck and arms (third day), 41.
Subjective.
Sensation like pin-pricks from within outwards in the skin of the face, and on the cheeks, forehead, head, and various other parts of the body (third day), 49.
Formication in the hands, especially the finger-tips (third day), 49.

SLEEP AND DREAMS

Sleepiness.
Yawns and is sleepy, yet cannot get to sleep, on account of a crowd of ideas which he cannot drive off (third day), 49.
Great sleepiness (second day), 41.
Great inclination to slumber, which, however, was frequently interrupted by dreams, 22.
Lethargic sleep after vomiting, 4.
Soporous condition, especially in children, 22. [540.]
Inclination to coma (third day), 41.
Great disposition to coma, which existed in three cases, 25.
Comatose state, 52.
Sleeplessness.
Complete sleeplessness, frequently lasting three or four days, 22.
Sleep uneasy, not refreshing, 22.
Sleep, restless, interrupted by dreams, 22.
Dreams.
Anxious dreams, frightening her in sleep so that she awoke (second day), 29.

FEVER

Chilliness.
Coldness (after forty-two hours), (after twelve hours), 48.
Coldness of surface (fifth day), 41.
Surface cold, and bathed in perspiration, 37. [550.]
Coldness of the skin, 22.
Skin became cold, 43.
Icy coldness of the whole body, 29.
Repeated shaking chill, so that the patient seemed to be affected with an intermittent (in one case), 22.
Shivering, 41.
Shivering in body (after twenty-five hours), 48.
Sensation of coldness along sternum, 51.
Coldness of the extremities, 45.*
Coldness and severe cramp in extremities (soon after), 41.*
Cold extremities, 15.* [560.]
Extremities icy cold, 25.
Upper and lower extremities of icy coldness, and covered with a cold sweat, 52.
Coldness and cramps of limbs (soon), 41.*
Coldness of legs, hands, and feet (after twelve hours), 48.*
Hands and feet cold, 29.
The legs continue cold for four days, 29.
Heat.
Skin warm, frequently covered with profuse sweat, 22.
Skin warm and dry, 22.
Pungent heat of skin, 43.
Fever (second day), 13, 18, 21. [570.]
Some fever, with a full, hard, frequent pulse, which was very variable without sufficient cause, even in the same case, in only four individuals out of thirty-one, 22.
Symptoms of acute fever set in immediately after the vomiting, etc., .

CONDITIONS

Aggravation.
( Morning ), Pains in bones.
( Evening ), Headache.
( Night ), Sweat.
( After drinking ), Vomiting.
( Lying down ), General symptoms, except retention of urine.
( Pressure ), Headache; pains in intestines.
( Sitting ), Anxiety, etc., in chest.
( Diarrhœic stools ), The sufferings.
( Vomiting ), Distress in stomach, etc.
Amelioration.
( Rubbing ), Cramps in calves.
( Diarrhœic stools ), Vertigo; general symptoms; pains, etc., of abdomen.

CUPRUM ACETICUM.