Cedron

Volume II — Main text

CEDRON.

Simaba Cèdron, Planchon. Rattlesnake beans. Nat. Ord., Simarubacee.

1. Provings.-I . CASANOVA. Result of provings on 14 healthy persons of different sex and age, drug being taken (1) in concentrated aqueous solution and I, and 3, dilutions of same, and (2) in substance and 1-3, trit. of same. Mind.-Gloomy, depressed spirits ; disposition to weep ; inquietude and excessive anguish ; dulness of senses, torpor of mental faculties ; dread of friends, females especially. Greater part of these symptoms were repeated in the m. (sic), and aggravated at n. Head.-Dull andheavy in e.; distensive ache, increased during n.; temporal arteries enlarged ; bending head backwards caused pressure in occipital and parietal regions, as if they would burst ; forehead cold, and as if empty in m. These symptoms were principally manifested in provers of voluptuous disposition and ofexcitable nervous temperament ; more also in women than in men ; they were, more or less, repeated every d. while under influence ofdrug. Eyes.- Prominent and red, with pressive pain extending to forehead ; pupils fixed and dilated ; in female prover, æt. 18, objects appeared red at n. and yellowish during d. for 7 d., until bellad. was taken as antidote ; lids injected, bright red, and painful on pressure ; swelling of meibomian glands. Ears. Buzzing towards noon ; hardness of hearing at n. Face.-Flying heat, alternated with chills, towards e., with bloated appearance ; cheeks red and burning at n., pale and cold in m.; pressing or tearing pain in one or both cheeks with occasional shoots under orbits ; spasmodic twitchings of upper lids, in 2 provers for 3 successive n. Mouth.- Dryness, with viscid saliva, while talking; thirst, with desire for cold water at noon and warm at n. and aversion to cold water

in e.; saliva becomes sour at n.; pricking of tongue early in m., going off after breakfast . Stomach and Abdomen.-Sense of heat and fulness ingastric region ; distension, and disposition to nausea, generally aggravated by rest, but relieved by walking and eating ; abdomen hard and distended towards e.; some flatulent colic in m.; stitches in spleen and liver ; constipation, with unsuccessful urging ; in some provers, after large doses yellowish or whitish loose evacuations . Urinary organs.-Scanty urine ; dark urine, with sediment, in both sexes ; frequent but ineffectual urging to micturate. Genital organs.-Much genital excitement ; in a young man discharge like gonorrhea, lasting 3 d., and only ceasing on medicine being omitted ; in a woman leucorrhea, and swelling of breasts with some pain. Respiratory organs.-Larynx constricted and tender ; dysphagia ; difficult respiration, with partial loss of voice, recurring at different intervals . Circulatory system. Oppression of chest and throbbing of heart, in almost all provers, especially those in whom febrile paroxysms were developed. Febrile paroxysms every d. in some provers, every other d. in others, towards 8 p.m., preceded by depressed spirits, dulness of senses, and pressive headache (at noon), cramps, then contracting and tearing pains in extremities, with cold sensation in hands and feet ; mouth dry, great thirst and desire for cold water ; chills and shivering, sometimes very strong shuddering of whole body ; palpitation and hurried breathing ; pulse weak and oppressed. These symptoms lasted 1-2 h., and varied much in intensity ; they were followed by sensation of dry heat, and then by profuse perspiration, full and quick pulse, with animated red face. Coldness and paleness in apyrexia, with thirst and desire for warm drinks. Extremities.-Pressing pains in elbows and forearms, with cold sensation, extending to hands ; lancing pains in knee-joints ; contracting pains in legs, as if produced from contusion, in e. When not precursors of fever, these pains were relieved by friction. Sleep.-Restless with confused dreams (in some of both sexes), in others very profound ; a general feeling of fatigue after awaking if time has exceeded 6 h., and weakness of body and mind. (Monthly Hom. Review, ν, 251.) 2. M. G. B-, man of 24, blond, delicate, but in good health at time of proving, mixed 10 dr. of 6th dil. in a tumblerful of water, and took tablespoonful every m. for 4 d., and m. and e. on 5th d. On 6th d., Aug. 30th, 1851, at 3 p.m. shuddering all over body, with malaise and desire to lie down ; shuddering is renewed on movement ; hands, feet, and nose are cold ; flying heat in face several times, which towards 6 became constant, face looking animated, with smarting in eyes (especially when closing them), lips dry, with desire to moisten them often, and headache, especially at bottom of orbits, compelling him to close eyes, and extending to occiput. While this congestion of head lasts shuddering continues all the time ; hands, feet, and nose remain cold ; urine dark red. 31st.-Malaise, with much weakness ; loss of appe-

tite ; red urine ; no stool. Sept. Ist.-As yesterday ; in e. copious stool. 2nd. Weakness ; in m. flatulent colic, with discharge of fœtid urine ; after talking, saliva becomes thick and white, like cream. At 3 p.m. paroxysm of 6th d. recurs, but much feebler. 3rd.-Weakness ; appetite returns ; transitory lancing pains in joints, especially r. elbow. 4th. All symptoms have disappeared. 5th.-Slight shuddering only towards 3 p.m. (TESTE, Mat. Med., sub voce.) 3. Mrs. T-, æt. 27, sanguine temperament, delicate constitution, disposed to cerebral congestions, though head is very small ; very sensitive to action of drugs . Of similar solution took tablespoonful m. and e. for 2 d. only. Ist d., 9 a.m., pain at elbow and r. forearm, as from shock or blow, for h.; oppressive pain in chest, extending every now and then to back, with frequent desire to moan and take long breath ; pressure at right temple, causing dull pain in whole r. head. These symptoms continue part of m., but disappear towards noon. Towards 6p.m. (immediately after dinner) cold all over, shuddering in back, icy coldness of feet, hands burning ; sensation in eyes as if one had wept a good deal. 2nd d., 9 a.m., pain in arm as yesterday ; distended abdomen, with borborygmi on 1. side. 6.30 p.m., shuddering in back and legs, unusual pallor of hands, red face, heaviness of head ; towards 7 stretching ; general coldness all e.; towards 9, in open air, increase of headache, pressive pain over eyes, as from a band. No thirst during shuddering. Dry heat at n. 3rd d., no perceptible symptoms in m. Towards 5 p.m. intolerable pricking-itching of tongue, obliging her to rub it incessantly against palate ; at same time taste as of iron in mouth, causing profuse flow of saliva, sour taste ; colic at dinner ; unsuccessful urging to stool. At 6.30 febrile paroxysm as on d. previous, but more intense, with smarting in eyes, which is only stopped for a moment by rubbing ; burning and weary pains in shoulders ; profuse emission of watery urine. 4th d., in m. pain at heel as from an abscess, only when walking, for I h. Towards 6 p.m. feverish paroxysm, similar to that of previous d., but less marked. 5th d., constipation. 6th d., pains in loins and back on rising in m.; towards 5.30 p.m. pricking at tongue and itching in eyes. On these d., and for three weeks from first, the febrile paroxysm returned, one d. stronger, another weaker. Various unpleasant sensations, such as bruised pain at elbow, or pains as from an abscess in heel, returned during first week every m. about 9. From third d. appetite decreased considerably ; alvine evacuations became less frequent, and headache, generally consisting in pressure on vertex, somewhat violent only at moment when shuddering commenced, soon ceased altogether. Face was generally slightly bloated. (Ibid.) 4. Miss C-, æt. 17, also very sensitive to action of drugs, took for a nervous affection of heart four globules of 6th dissolved in water. It did heart no good, and towards 6 p.m. (medicine having been taken at 9 a.m.) she had shuddering, soon followed by dull and heavy frontal headache, spreading to both parietal regions, with redness of eyes and itching of inner and outer surfaces of lids ; icy coldness of hands and tip of nose, even in midst of febrile reaction (pulse 80), rest of face being red and burning ; lastly, dimness of sight, dilatation of pupils ; VOL . II . 4

objects look red ; mouth dry, with thick viscid saliva ; constriction of throat, which scarcely allows her to swallow saliva ; anxiety, restlessness, general malaise. N. restless ; no sleep, with flow of confused ideas until 5 in m. (patient till then had slept well) . On 2nd d. no other symptoms but those of malady till 5.30 p.m., when paroxysm similar to previous one occurred. She took a dose of lachesis, and had no recurrence. (Ibid.) 5. I. DOUGLASS, æt. 29, took, Jan. 7th, 1859, at 7 p.m., I dr. of tinct. In 20 m., pulse increased by 15 beats. In 10 m. more, pulsating in temple, and twisting pain behind r. ear, changing to dull pain, and extending to temples, head felt as if swollen ; singing in ears as of crickets. Had (unusual) erotic dreams, with priapism in m. Before rising on 8th, rising of bitter wind from stomach, with dull pain in temples. At 7 p.m. took 2 dr. Inth. pulse increased by 15 beats, very full ; pulsations in temporal arteries ; pressure in ears ; soon sensation as if whole head was swollen ; sharp pain in occiput. At 9.30, head same, burning sensation in upper lids. All n. very restless, frequent waking, fatigued from lying long in one position. On m. of 9th pressure in occiput ; slightly yellowish coat far back on tongue, with nasty, sickish, bitter taste in mouth. That n. as on 7th, and gastric symptoms same next m. (10th). At 10.30 a.m. occasional sharp, jerking pains in occiput. At noon sharp pain by turns in cæcum, liver, and spleen, successively in occiput, abdomen, and legs. Pains in head all dull, save those in occiput, which are acute. At 10 p.m. dull pain on vertex, with sharp flying pains in all joints of extremities, worse in feet, especially in great-toe joint. Took 2 dr. and went to bed. In about 20 m., with former increase of pulse, pains over ears. On getting warm in bed, severe sharp flying pains in all parts. Those in limbs seated in joints, especially great-toe joint, and streaking up bones ; those in abdomen chiefly in ascending colon, liver and spleen ; was kept awake by these most of n., pains of lower extremities being especially severe. 11th.-Awoke late, after sound sleep, with dull pain in vertex ; 1. eyelid seemed dried to ball ; conjunctiva inflamed and dry; tongue coated yellow, even to tip ; sickish, slimy taste ; pulse 95, full. II a.m., considerable fever, pulse 100, pains continue ; redness of white of eyes, which were exposed. 12th.-Slept well, awoke with dull pain in whole upper head ; mouth as before ; copious stool, with excessive tenesmus. 10 a.m., with headache, throbbing in temples ; pulse 90. The flying arthritic pains continued, more or less, for more than four weeks ; relieved by motion and cold before soreness of joints set in, then aggravated, worse at n. From first, urine scanty and high coloured. Thirst at n. and during febrile symptoms. (N. Am. Four. ofHom., viii, 120. ) 6. Miss C-, æt. 18, bilious plethoric habit, took, Jan. 8th 3 dr. of tinct. In h., pulse 90 ; throbbing in temples, increasing to pain ; eyes felt swollen ; misty vision as from thick smoke ; pain from temple to temple over eyes ; rolling pain in stomach. 9th.-Awake and restless all n., waking dreams ; pain in temples ; excessive thirst ; feet very cold, went out barefooted in snow and returned to bed, when they

warmed up. Rose early, was dizzy, and could not see to light a candle or when it was lighted. Did not know her friends ; was obliged to go to bed, but could not undress herself; fell asleep and dreamed of quarrelling with a dead sister and other dead friends, cried about it, and awoke with a nightmare, with sensation as of stone on stomach. Rose with pain in region of liver. At II a.m. slight dizziness. (Ibid.) 7. Mr. W-, æt. 19, nervous-bilious, took I dr. In h. pulse quickened by 12 beats, firm, full; beating in temples, increasing to pain, and extending over ears. During n. restless sleep ; priapism in m. Sharp lame pain in r. ankle ; tongue coated yellow ; nasty taste in mouth. (Ibid.) 8. Mrs. M-, æt. 33, took 1 dr. In h. pulse and head as in No. 7 ; pain in a decayed tooth for first time ; restless sleep. (Ibid. ) 9. Mrs. B- took 2 dr. 2 e. in succession. Same symptoms of pulse and head ; alternate dryness and smarting with moisture of eyes ; smart rheumatic pains in joints of all limbs, with swelling of feet ; frequent emission of large quantities ofpale urine. (Ibid.)

Volume II — Appendix

Cedron.-(Additional provings.) 10. A. W. W-, man of 20, in good health, Dec. 1st, 1866, at 7 a.m., took 5 dr.oftinct. In 10 m. felt flush or feverish glow over body, pulse 10 beats quicker, burning and smarting in mouth and fauces. At noon 6 dr., with same result. At 5 p.m., 15 dr. Pricking and tingling in throat and fauces, seeming to extend some way down œsophagus; bad taste in mouth; slight pain in temples; febrile symptoms as before. All had disappeared in 2 h. 2nd.-At 7 a.m., 30 dr. Besides former symptoms, metallic taste and pain in bowels-these for but a few m. At noon, 50 dr. Besides former symptoms, some pain in region of kidneys, profuse secretion of urine, smarting and burning in urethra. At 6 p.m., 60 dr. Only new result was uneasy feeling in lumbar region,with feeling as if there was a drop of urine in glans penis. 10th.-Again took 60 dr. at 7 a.m. Profuse secretion of urine; warm feeling over surface of body ; pain in kidneys ; burning in mouth, fauces, œsophagus, and stomach, as if m.m. was raw; colicky pain in small intes. tines; continued pain in temples, passing from side to side; pain and burning in urethra when not voiding urine; feeling as if there was a drop of urine in urethra, or a constant dropping from it. (Dr. STENNETT'S Provings, West. Hom. Obs., ii, 11.) 11. S. M. P-, man of 24, healthy and not susceptible to medicine. Dec. 1st, at 7 a.m., took 5 dr. of tinct. At 10, sharp cutting pain in both elbows; pain under scapula and in pelvis. At noon, 15 dr.; at 4.30 p.m., 30 dr., after which profuse discharge of light-coloured urine. 2nd.-At 7 a.m., 50 dr.; at noon, 60 dr., after which sharp darting cutting pains under both ribs, continuing till 4 p.m.; also profuse secretion of urine,with numb, uneasy sensation in urethra. At 6 p.m., 100 dr., which caused in h. all above-named symptoms, with pain in r. side for 3 h. 3rd.-Pains in side and under scapula returned at 3 p.m., although no medicine was taken; also at 4 p.m. next d., though less severely. 5th.-At noon 60 dr. Pain under floating ribs and r. scapula, also in elbows; abundant glassy mucus in nose ; copious urine. (Ibid.) 12. a. S-, man of 27, in good health,but very susceptible to drugs. Dec. 1st, at 7 a.m., took 10 dr.oftinct. In few m. burning and scraping in mouth andthroat, with profuse discharge of thin saliva. At 8 tingling sensation in mouth. At 9 took 10 dr. Caused same symptoms as before, with heat over entire body; pain in occiput and forehead; slight pain in kidneys. At noon, 15 dr. In 1 h. severe pain in kidneys, and soon after profuse discharge of thin, clear, transparent urine. At 3.30 p.m. severe shooting pain over 1. eye ; numbness in r. leg; numbness and dead feeling in r. hand and forearm, so that he could not hold pen; felt debilitated. At 4p.m., 20 dr. Some pain andnumbness again, lasting 2 h. 2nd.-At 7 a.m., 40 dr. Caused all previously noted symptoms,with excessive pain and burning feeling in kidneys and along ureters, as if boiling water were passing through them; colic and cramp insmall intestines; slight nausea; pressure onchest, as from a heavy weight ; malaise; profuse secretion of clear,thin mucus in bronchi ; acrid tears,seeming to scald cheeks. These symptoms passed off in about 4h. At 9 took 40 dr. Could not sleep; restless and very nervous; all above-noted symptoms again present save pain in temples, and continued till 5 a.m. next d. 3rd.-At 7 a.m., 50 dr. New symptoms were profuse discharge of thin, clear, acrid mucus from nose; smarting andburning in eyes, with great discharge oftears. At 11 took 65dr. Pulse somewhat accelerated; pain over r. eye and in temples, with numb, dead feeling in legs, as if much enlarged; sleepy and drowsy. At 6 took 75 dr. Severe sharp, griping, cutting pain in lower abdomen; profuse secretion of saliva, with metallic taste. Last-named symptoms increased in e. and lasted through n. into next d. 6th.- Having gotwell again, took at noon 150 dr. No new symptoms. At 7.30p.m., 150dr. Onlynew symptom present was a sort ofjerking and twitching of tendons of legs, especially of tendo Achillis and in r. foot. All old symptoms likewise pre-

sent. 7th.-Took 100 dr. Neuralgic pains, soon followed by numbness over entire body, with smarting and burning in nose, were produced by this dose, with all urinary symptoms much aggravated. These distressing pains continued with more or less severity for nearly 3 d., by end of which they were all gone,having disappeared gradually. 12th.-200dr. All old symptoms, strongly marked, came on in about I h. Urine very high-coloured, and, on standing for some time, threw down a branny precipitate. 15th.-300 dr. during d. Burning in mouth, throat, and stomach; colic and cramp in small intestines ; pain in kidneys, burning in urethra and along ureters, profuse secretion of urine; oppression on chest; numbness of hands, arms and legs ; and all previously noted symptoms,were present during next d., and those affecting kidneys lasted for 2 d. They did not pass away as rapidly as they came on, and seemed to take a deeper hold on the structures affected than had been the case before. b. Same proved powdered nut. Dec. 18th took 5 gr., on 19th 15 gr., on 20th 80 gr. Symptoms were not different from those produced by tinct., but seemed longer in coming on. 21st.-Took 160 gr. Profuse secretion of tears, which instantly ran down face ; also burning in urethra, and thin gleety discharge d. and n. , with feeling as if ants were crawling over body. Pain in kidneys was excessive. 22nd.-Took 200 gr. Before-noticed symptoms came on again to-day, and lasted some 36 h . For 2 d. more or less pain in kidneys, with slight derangement of biliary secretion, evinced by colour ofurine and by stools. (Ibid.) P. 49, 1. 3, for " urine " read " wind. " L. 6, before " All " read " Nearly." L. 9, for " very small " read " rather small than large." L. 29, for " burning " read " stiffness ."*