Mercurius iodatus ruber

作者：Richard Hughes & Jabez P. Dake — A Cyclopaedia of Drug Pathogenesy

Volume III — Main text

MercuriUB iodatUB, mercurous iodide, Hg I.

L Prttnngs.-^i. Dr. X. S. P. Lord proved ist trit.* Dull headache on awaking at n. ; dull heary aching at base of brain, in throat and nostrils. Feeling of dryneis in teeth \ grinding >cnsation in roots ot teeth, with occasiunal pains in abdomen (and d.) ; creeping grinding sensation at root&of teeth with pressing together, and senw of forcness deep behind umbilicus (4,th d.) ; sen^tion of fulness, grinding, and drawing in roots of teeth, with constant desire to prc4s teeth together, — he had pres&ed ihcm so hard during sleep that the muscles were lame and tired on awaking ; gums feel slippery ; increased flow of saliva, with congested feeling at the mot ofa tooth(iith — 1 3th d.)> Sense of dryness in throat ; dull, heavy, aching pain in throat ; fauces and roof of mouth dry, gumi and i^ide of mouth moist ^ sensation of nausea and faintness, with pressure high up in rectum (4th d.) j sensation of strings of air-bubbles running transversely across abdomen below umbilicus, — also a shooting pain, as of a knotted string, down, through, and across, above the umbilicu:* j loud rumbling in boweU (md a.) ; occassional pains in abdomen, with grinding ^sensation in roots of teeth (10th d.); frequent short darting pains in 1. abdomen, and occasionally in r., running from deep in pelvis up to hepatic region- for 61 d., constant daily return at « a.m. of a heavy unca-«y sensation below umbilicus, as it full above and empty below, with a kind of pressure towards anus and sensation as it it could not move at all, succeeded by feeling as if an acrid loose stool would be diKharged. and then of fkintness and sickness in hypogastrium, and frequent painless discharge of inodorous flatus. Slight constant diM:hargr of mucus from urethra, with slight soreness around gtans ; diuresis (5th, 7th,and qtn d.). Some tightness and pressure In lungs. Aching and drawing pain in bone^ of 1. forearm, and some pressure in hypogaAtrium» at midday, returning at 9 p.m. with passage from bowels ^ sense of lamenesa in foot. Profuse sweat of genital organs. (Allen's £iuy(iopaJi4t, vi, xSg.)

  • Manner unknown in mil these provingi.— -Boa.

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■IHpiH MERCURIUS lODATUS. 067

*. L. J. B — took ix and ax trits. Fine bright red eruption on roof ot mouth ; several sharp sudden pains in r. chest, from above downward ; while in bed at n., severe pain In 1. femur and dull pain in sAcral region, lasting 24. h., relieved by motion, stretching, and turning from side to side. {I6U.)

  1. Miss R — took 2nd, 3rd, 5th, and lath dec. potencies. Bad headache on awaking, in forehead, as if sword were run through from I. temple to r., al«o in occiput bruised pain as from a blow (after lo^ h.) ; dull pain above I. temple, followed by throbbing pain in r. ; very sharp pain on top of head, lasting a long time, after 4. d. j sharp pain in occipot, after rising in m. Sharp lasting pain in superior arch of ]. orbit, as if irom knife. Tongue coated yellowtiih white ; small, red^ rai^ed elevations on tongue. Burning in throat when swallowing saliva ; burning in throat, with pain when swallowing; tonsils slightly swollen ; empty deglutition, she is obliged to swallow frequently. Burning at stomach with pain as if from a blow (tst and snd d.) ^ bruised burning pain at stomach, more severe than any preceding it (4th d.) ; sharp, cutting pain m stomach, with nausea and inclination to vomit, in m. when awaking, and lastinz all d. Patn in I. hypochondrium, with dizziness on avraking in m., and lasting all d. Sudden darting through r. side, as if from a sword. On the 7th d. excruciating, sharp, sticking pain in back (dor%al region), causing her to shed tears, lasting | h. ; it returned next d., but not so severely. Dull

fiain behind both ankles in m., on rising; sharp, cutting pain in small toe of I. foot, »5ting 1% h. {JhU,)

  1. Erncst W — took ax, jx, 9X, and lax. Pressive aching in frontal region, lasting a short time, after 3rd d. ; dull headache at r, temple. Pinching pain m r. elbow, lasting few m. ^ slight aching pain in r. elbow. Pinching pain in r. knee, lasting a d. and a n., followed shortly alter by pain of same character in r. elbow ; pressing, squeezing pain in 1. knee ; pinching pain behind lower third uf r. leg ; aching

f>ain on anterior surface of 1. leg; achirig on internal surface of 1. leg above ankle, asting about 1 h., followed by aching m forehead ^ severe aching pain in r. leg, on posterior surface, immediately followed by pinching pain on posterior surface of r. tbrearm ; pressing, squcciing nain in r. ankle ; sharp cutting pain in r. ankle, after i h. [ aching on dorsum of r. foot. {Ibid,)

  1. Miss X — look ax and 3X. Dizzy headache, like rush of blood to head, followed by violent pain above r. temple j headache in m. when rising, lasting over I h. i headache with faintness, while m church (38 h.) j general headache (ij d.) \ slight headache all forenoon ; bad headache all over head (as h.) \ violent headache, especially over r. temple (iS h.) \ very violent headache, involving entire head ; very violent headache, lastmg some m., over r. halfof ft'ontal and r. parietal bones (19 h.) ; slight general, dull headache on awaking (11 h.) } sensation in skull as if it were cracking, continuing the whole afternoon (17th d., also on 19th); increased throbbing pain in head, more in forehead, after 49 h. ; headache is always on top of head, or on r. side ; headache is worse in m. before rising, and for short time after rising, also when she walks about in house ; headache over top of head (after 46 h., 8tn d.) ; headache all over top of head, proceeding after some time into forehead ; headache all over top of head, with wave-like motion of the blood, after i h., ist d., recnirring all over bead on 5th d. j slight headache over rop of the head, loth d.; shup pain on top of head, followed by pain in r. hip, after | h. j pain in r. side of head { slight pains in r. side of head j violent pain in 1. side of bead, near 1. temple ; violent pain over entire r. side of head, extending ft-om r, temple to nape of neck, lasting longer than usu.it (13 h.) ; rather violent pain in r. side of head ; very violent pams in r. side of head j sharp, aching pain in r. side of head (3 d.) ; sharp patn in r. side of head, extending to neck and r. eye (4 d.)i several slightly sharp pains in 1. side of head, above I. temple (a d.) ; very short, sharp pains in r. side of head. Sharp pain in the septum narium (4 d.). Sore-throat, with difficulty in swallowing and frequent empty swallowings } severe burning in r. side of neck, as if a coat of fire were laid upon it, continuing, but not so severely, fur a few m. Nausea ^a3 h.) ; nausea, with disgust at iight of^food (before supper) ; nausea, with suffocation about heart, and dixiiness (35 h.) ; white at dinner, inchnation to vomit, obliging her to cease eating ^66 h.) ; inclination to vomit, with dull, dizzy pains over top of head, following immediately after a slight pain at heart (93 h.) \ strong inclination to vomit, after 45 h. j slight pain in I. side of stomach (ajrd d.) ^ several short, rather burning paim in 1,

itoroich (10th d.) { dull, conitrictive pain in itomich, followed shortly ahcr

diaht I ude of

by aching pains in r. arm and shoulder (Sx h.); rather severe cramps in stomach, followed immediately by pain in r. side of back ; sudden, sharp, momentary pain in stomach, as if a knife were driven in. Aching pain in region of liver, proceeding from r. side to 1., producing dizziness and nausea j two successive shaip pains in r. hypochrondrium, followed by sharp pain through stomach, with sensation as if |»in had turned around ; slight sharp pain in r. hepatic region j very sharp pain under r, floating ribs ; very sharp pain in 1. hypochondrium. Several successive violent pains in chest (i^ h.) ; sharp pain in the chest, behind sternum j rheumatic pain in r. side of chest (17 h.) ; dull, continuous pains in r. side of chest, at n. while in bed ; aching pain in r. side of chest j sharp pain in 1. side of chest j sharp pain in r. side of chest, followed by slightly sharp pain in i, side ; sharp pains in 1. side below axilla, followed by a double pain on top of head ; short, sharp pain in r. side, — a few m. after, the same pain appeared further back under arms, with aching in r. side of chest, followed by soreness in chest as if from a cold ; stitches in r. side of chest (15 h.) ; sharp throbbing pain in 1. side of chest } the pains in chest appear on 1. side, those whi£fi appear on the r. side always proceed to 1. Sudden but lasting pain in 1. side, about heart, taking away her breath ; slight pain tn heart, when yawnmg; sharp pain about heart (3 d.) ; rather sharp pain at heart ; slight stitching pain at heart (14 h.) $ sudden spasmodic action 01 heart, as if it jumped out of its place. Slight, sharp pain in 1. side of neck j several violent pains in back (1 h.) ; aching pain in back (} o.) ; sharp sudden pain in 1. shoulder-blade; sharp pain in 1. scapula (a i h.) j sharp, cutting pain in the back, between shoulders, — x h. after, same pain appeared lower down, about last dorsal vertebra (a d.) j throbbing pain between shouldeis ; sharp pain is lumbar region ; sharp pain in small of the back. Pain in r. arm and sole of r. foot (9a h.) ; dull, lasting pain in r. forearm, and simultaneously in I. hip ; sharp paun in 1. shoulder (45 h.) ; sharp pain in r. shoulder, with aching pain in back ; pam in 1. arm above elbow (39 h.) ; dull, aching pain in 1. elbow (65 h.) ; rheumatic pain in 1. arm below elbow, proceeding afterwards into 1. thumb ; dull, aching pains in both forearms (75 h.); pain on back of r. hand (91 h.) ; pain in r. hand, followed by rheumatic pain above 1. elbow (3 d.) ; rheumatic pain in r. hand at n. in bed ; rather sharp pain m palm of r. hand ; several sharp pains in 1. forefinger ; rather sharp pain in palmar surface of r. thumb, with slight pain on top of head (75 h.). Rather sharp pain in r. lower limb, extending into loot (3) d.); sharp pain in r. thigh (i^ h.)s sharp pain in r. thigh, followed shortly after by slight pain in the nose; slightly sharp pain in r. thigh, above knee; pain on anterior surface of r. leg above ankle; four successive pains on 1. teg above ankle, at intervals of 15 m. (i h.) ; sharp pain in L leg, between foot and knee ; slight lasting pain in sole of 1. font, followed by sharp pain in 1. chest (56 h.) ; pain in sole of 1. foot, with feeling of faintness through tbc whole body (99 h.) ; pain in sole of 1. foot, extending through into large toe and proceeding halfway across dorsum of foot (4 d.) ; pain in sole of 1. foot, relieved by movement (5 d.) ; pain in large toe of 1. foot, with itching on large toes of both ftctj pain on dorsum of large toe of 1. foot, with sharp pains in fingers of r. hand ; slightly sharp pain in large toe of r. foot ; short, sharp pains in 4th and 5th toes of r. foot, Faintness, with feeling that it would be relieved by lying down ; deadly faintnes% with entire loss of muscular power, followed by spasmodic motion upward and down. ward of lower jaw, which continued throughout next d. ; while in church felt as if she would faint. The following symptoms appeared in rapid succession at n. 1 pain behind I. ear, followed by pain in tips of fingers of r. hand and a pain in sole of r. foot near the toes ; slight pains in toes of I. foot, followed by pain in back part of head, then in forehead, and finally near r. ear; sharp pain in toes of r. foot; sl^ht pain about heart ; violent pain in r. side of head, pain in heel of r. foot, followed fay pain above r. temple, and afterwards by sharp pain in 1. side of neck. A small, stinging pimple appeared on r. cheek, shortly after one in exactly the same position on f. cheek, the latter was more itching than stinging; itching on sole (rf* 1. foot; slight stinging in 1. cheek. Frightful dreams and nightmare ; frightful dreams of drowning and of coffins ; nightmare, she thought that an immense sheet of letter-paper was coming down over her to smother her. Occasional general chilliness ; chills with trembling all over body (3 d.) The pains are felt more on the r. side ; the pains are better during pressure, but as soon as this is removed the relief passes awav. (iiMgf.) 6. Dr. Jas. BLAKELEYtook ist to6thtrit. Lively, good-natured, and talkatiTC; he feels very lively, whistles, sings, and is disposed to be decidedly meny'and gbod-

natured, (soon after great deprfsuon) j from noon till 4 p.m., feels depressed, From 4 to 6 p.m., is lively and cheerful, from 6 till i», all symptoms arc a??ravated j while in opm air always feels cheerful, in a warm room he h generally dull and deprcued. Dulness of head, with severe, dull, frontal headache, when awakmg at n, ; dull, heavy condition of head, with dull *soreness« of bones of face (this last constant throughout whole proving) ; head feels dull and heavy (6 h.) ; dull headache on awaking in m., which continues till he exercises, after which It passes off ; dull headache entire forenoon i dull headache with soreness of face and nose, the entire e, ; when he awakenft at n. alway!^ has a dull headache ^ dull headache, aggravated by pressure; dull head, ache, e-ipecially at r. temple, with nausea and fcelimg as if he would vomit; dull headache, with dtdness of the head, in a warm room; entire head feeU dull and compressed, and as if pressed down upon pillow by a heavy weight (i» h.) ; dull pressivc ncadachc after dinner (3 h.) ; occasional sharp stitches through head and face; the severe lasting pains occur on the r. side ; the pains in hea<l and tace are relieved during pressure, but are worse after this is removed ; in bed at n., very severe headache over the r. half of forehead and r. e^r, with severe pain or dull soreness in r. orbit and eye> ball ; dull heavy pain over forehead and temples, extending down sides of face (| h.) ; dull frontal headache, especially affecting 1. orbit (4 h.) ; dull frontal headache, with pain at root of nose (| h.) ; dull frontal headache the entire d., with occasional sharp stitches through head and face (a h.) ; dulUrontal headache the entire e. (3 h.) ; dull frontal headache with pain in orbits and root of the nose, when awaking at n. ; sudden severe and sharp pain m r. side ot forehead, above r. temple; severe shooting pain in forehead, superior arch of the r. orbit, and root of nose ; steady, aching patn in r. temple (} h.) ; momentary pressivc pain in both temples (j h.) ; occasional shooting pains in remples (| h.) ; severe sharp pains in r. temple, at n, in bed; severe sharp stitches in both temples, while going down stairs ; pain in 1. parietal bone, aggravated by touching part, and by combing hair(i|h.); dull pains in the r. and T. sides of head, in front of ears (| n.) ; dull pains in entire r. side of the head, with stiffness in nape of neck, and sensation as if r, ear were closed up ; numbness of occiput and nape of neck, with stiffness of neck ; numbness and tingling of scalp (11 h.) ; itching of scalp ; persistent itching on top of head, at n. in bed. Pain and soreness of entire r. orbit (} h.) ; pain in superior arch of!, orbit with headache, aggravated by noise and talking ; (lull pain in inferior arch of r, orbit; dull pain in superior arch of 1. orbit, with dull frontal headache ; slightly dull pain in superior arch of 1. orbit, and in 1. malar bones, painful when touched i sharp pain in superior arch of 1. orbit ; sharp pain in inferior arch of L orbit and 1. eyeball, with feeling as if lachrymation would occur ; sudden sharp pain in superior arch of r. orbit, aggravated by stooping (la h.) ; severely acute pain in superior arch of r. orbit, on rising in m. ; when lying on 1. side, black clouds float before eyes, this never occurs when lying on r, side. Dull pain in front of both ears ; sudden, sharp pain in external meatus ofr. car ; stinging throbbing pain in 1. external ear; sensation as if r. ear were closed up, although his hearing remained good ; at n., while in bed, dull pain in Internal meatus of r. ear, followea immediately by itching of small spot on top of head ; boring pain in internal meatus of r. ear; sharp, intermitting boring in internal meatus of r, ear (1 h.); sharp throbbing, boring pain from within outward, deep in 1. earj touching r, ear, or introducing finger, causes sore pain in ear, and also aggravates the headache on that side. A great deal of mucus in nose, obliging him constantly to clear it; pain at root of nose (la h.) ; steady, dull pain at root of nose; severe shooting pains at root of nose; severe throbbing pam on r. side of nose, deep in bone; r. side of septum narium and r. nostril are very sore and much swollen ; for 3 d. sore painfid spot on I. wing of nose. Dull soreness of the whole r. side of face, especially r. half ot inferior maxillary bone ; dull painft in 1. tnaiar and r. orbital boners ; slightly dull pain in 1. malar bone, which ig paintul when touched ; sharp pain in 1. cheek, with soreness of I. half of inferior maxillary bone ; steady sharp paJn m upper portion of I. malar bone, which is painful when pressed ; sharp throbbing pain in r. cheek, with same on external surface of r, forearm ; dull bruised pain in r. malar bone, radiating into forehead and r. side of head ; at same time a small spot at end of one of the radii pulsates and bums like fire (| h) ; dryness of lips, with burning dryness of lower Hp, and sensation as if upper teeth were pressed tightly together j deep boring pain in ramiu of r. side of inferior maxillary bone, extending up to r. orbit. L. lower molar teeth fielt so long that he could not eat ; pain in a I. molar teeth.

igrihcFj with freling a% if they

long; dt>

aggravated bv bringing^ lh«

agreeable feeling in terlh, as il they were veiy tight in their sockets (i d.) ; sensation in upper teeth as if ihey were pre^wd tightly together (3rd and loth d.). The cool* ing on the tongiie prescntx occasionally a light brown colour ^ tongue thickly coated with yellowish brown fur; tongue is coated bright yellow, lip and edges being red ^ the tongue retained through entire proving a thick, dirty yellow coating ; on rising to m. back part of tongue is covered witb a thick, dirty )tIIow coating; tongue thickly covered with a yeIlowi«h>white coating { tongue slightly coated at back part; coating on tongue is always on back part, front, with edges and tip, being clean i the papillr can be prominently seen through the coating on tongue; small raised blisters on back part of tongue ; dryness of mouth and throat, with frequent empty swallow* ings ; dry and sticky condition of mouth, gums, and teeth ^ constant secretion ot mucus in throat, dimciik to dislodge, and causing retching; exce^Mve secretion of mucus in throat ; in m. there is very much mucus in throat ; a great deal of mucus descends through posterior nares into throat ; dryness of throat, with sharp pain above epiglottis and in I. tonsil when stvallowing, also in I. halt of hard palate ^ throat dry and burning, with pain when swallowing ; the throat and nose are dry, and feel as if entirely closed up with mucus; sensation as if a lump were in throat ; burning in throat; for several d. throat has felt swollen ; tonsils, uvula, and pharynx are red and congested ; the mucous patches on tonsils and walls of pharynx are easily detached ; pain and swelling of r. tonsil ^ slight pain in r. tonsil^ wiih sensation as if it were swollen, with pain when swallowing; posterior wall of pharynx is red, irri. tated, and inflamed, and dotted with patches of mucus and small spots which look ulcerated ; pricking*burning pain in r. side of pharynx j steady, sharp pain in r. side of neck, extending over r. side of head (% h.) ; soreness, with sensation of stiffness (but without actual stiffness) in r. side oi the neck, followed by slight pain in internal meatus of r. ear, going through into throat, and causing dulness in ear and sensation of swelling in the throat, with disposition to swallow frequently. Desire for acids not very great, but stronger than he ever had before ; frequent want of appetite, with di»gust at seeing food. During proving appetite was very variable, at one time excellent, and at another entirely wanting; sometimes an excellent appetite until sitting down to eat, when, at sight of food, it would vanish ; the smell ol food while cooking would sometimes remove the appetite ; during proving there was great thirst (principally in e.) for water, of which he drank large quantities ; occasionally there was thirst for acid drinks. Slight nausea ^ weak, empty feeling at stomach, with slight sensation of nausea (aj h.) } steady, sharp pain in stomach, with hardness of the stomach and abdomen, pain increased by pressure. Slight aching in I. hypochondrium ; excessively acute, stitching pain in r. side below ribt, he could not speak without gasping, and had to stand with his hand pressed against his side, which gave Bome relief j Kvcre stitching pain (immediately) at umbilicus, with dull, tired feeling in small of the back, oppression of chest, dull pain above r. temple, and pain in r. shoulder, worse when using arm, immediately after lying down at n. ; hardness of abdomen, as if from incarcerated flatus j rumbling in abdomen, with escape of flatus, at n. while in bed; feeling in abdomen as if diarrhoea would come on ; cutting pain in abdomen, with great discharge of flatus, followed by a small stool, consistmg of hard black farces, with stinging and burning at anus (at 11. } ; slight cutting pain in abdomen, 1^ith inclination to stool, but with evacuations only of wind ; colic pain in abdomen, with sensation as if escape of flatus would relieve ; slight colic on awaking ; slight colic pain in abdomen, with great discharge of flatus on awaking in m. ; severe colic pain in abdomen. Small, soft, diarrhtelc stool j copious, very (hm, light brown stool, accompanied by froth and wind, and preceded by cutting pains in the abdomen ; in m., thin, light. coloured stool ; emission of exceedingly foul. smelling flatus, followed by immediate inclination to stool, which was small, thin, and very foul smelling; copious, soft, dark'brown stool, with soreness at anus; copious, soft, dark brown stool, with buming.stinging at anus; slight cutting pain in abdomen, followed immediately by a copious, soft, yellowish brown stool (the stools always follow immediately after the colic pains); copious light'brown stool, consisting first of tolerably compact fxces, then of soft f<eces, and finally of froth ; small stool of very tough faeces, almost of consistency of putty, requiring great straining for their evacuation | after much straining and exertion he passed two small lumps», about the size of beana, of hard black fieces, covered with white and green mucus, at n. ; the stools which

occur in the ciaytime are copious, *oft, and of a dark or light yellowish-brown colour, the stools St n. are H'anty, hard^ and black. During entire proving urine has been copious, ind of dark colour. Occa.Monal sharp shooting stitches in end of pents^ through glans ; Kminal emi&fiion, of which he knew nothing until m. ; copious seminal emission, preceded by lewd dreams. Slight hacking cough, when inspiring. Oppressed feeling in chesty dull boring pain in r. side of chest, at 6th rib; sharp stitches, as from needles, in I. side of chest, produced by pressure on stomach. Pulse weak, irregular, and labouring, about 80 per m. Stiifness of neck; stiffness of entire neck, with pain when turning head (*yd d.) j great soreness and Miffness of neck, with sorene&s and numbness of back between the scapulae ; dull pain over the I. scapula; sharp sticking pain in dorsal region of back j very severe pain, as if bruised, over entire scapular region ; throbbing pain on r. scapula. Wearied feeling of all limbs, especially when lying on 1. side, relieved by lying on r. side ; heaviness of limbs, with laziness and drowsiness; bone pains, generally felt deep in bones. R. arm is lame and tired after writing; slight numbness and wearied feeling in r. arm, aggravated by writtne (while other motion but very rarely produced or aggravated this s^'mptom, it constantly appeared as soon as he began to write, and disappeared when nc had finished) ; lame numbness of I. shoulder and entire I. arm { dull, heavy fieeiing in entire r. arm ; r. arm, especially in bend oi elbow, is very painful on rising m m., none from passive motion ; laming rheumatic pain in r. arm, aggravated by writing; severe dull pain in the r. arm, deep in the bones, aggravated by writing ; soreness and lameness of the 1. shoulder and arm every n. when ^tng on the 1. side (previous to proving the drug he always lay on his I. side, and without inconvenience; now he must frequently lie on his r. side); entire r, arm is very sore and painful, worse from pressure, rubbing, and passive motion ; the pains in r. shoulder, arm, and hand, are reproduced and exaggerated by writing ; lameness and ftiffriesA of the r. shoulder; severe pain in r. shoulder, obliging him to cease writing; sharp pain in the r. axilla; sharp pricking pain at back of r, shoulder; nain and soreness of I. arm and elbow, in e., at n., and in ro. on waking; sharp Doring in r. arm, above the elbow ; continual dull pain in bend of r. elbow ; sharp, stabbing pain in bend of r. elbow; dull laming pain of 1. forearm and hand; sharp pain in I. wrist, extending (but more severe) into thumb, followed immediately by snarp intermitting pain on dorsum of I. foot, extending into the 3rd and 4th toes; sharp aching pain in radial side of the r. wrist, aggravated by using limb or by twisting wrist (on awaking in m., and continuing all d.) ; weak, numb feeling, with cramp-like pains, of r. hand ; dull pain in palm of I. hand, with numbness ot fingers and inability to grasp objects (at n. while in bed) ; throbbing pain in palm of I. hand, extending up arm into 1. chest; numbness of fingers of both hands; sharp throbbing sticking pain at base of 1. forefinger, with lameness and stiffness of whole finger ; sharp prickings, as it (rom needles, appear simultaneously in first joints of 3rd and 4th fingers of both hands, with stiffness of fingers, — the prickings are aggravated by moving or bending the fingers; throbbing pain on palmar surface at base of the I. thumb, with paralysed feeling of thumb. Weariness of lower limbs, with dull pains and tingling (3 h.) ; tearing pain along anterior surface of r. thigh and leg from hip to middle third of the leg, relieved by pressure and motion, wofbe when at rest (4 h.); pa&sive motion causes tingling through entire r. lower limb, even to toes ; aching pain m r. hip-joint ; deep boring pain on the external surface of I. thigh, apparently in femur, confined to a small spot, and very persistent (pain is dull, and thigh feels as if it had been beaten),— pain in thigh left after lasting 3 h., but was reproduced by shaking limb, and was then accompanied by tingling in r. and 1. legs, feet, and toes, aft if they were going to sleep ; throbbing pain on internal surface of r. knee the whole c.; heavy laming pains in calves of both legs, with pain in I. knee-joint ; deep throbbing pain on external surface of r. leg, apparently in tibia (this pain returned after 4 d.) ; severe laming pains on posterior surface of both ankles (on awaking in m.); sharp boring pain on anterior surface of I. ankle ; cramp-like pain in 1. -side of sole of I. foot, with numbness of I. leg. At 4 p.m. he had to lie down from great weariness; disposition to sleep, with sleeplessness; he felt better after lying down a short time; indisposition to do anything, with desire to lie down and rest; he feels languid and sleepy; excessively tired feeling of whole body, especially of Umb$, with indisposition 10 do anything, and desire to lie down, with dull aching in forehead and bones of ^ce. T^e pains are steady, dull, throbbing, and boring, also sudden, sharp, stinging,

n

n

17%

and pncJcing ; slight itickmg pains in both' scapular, in r. temple, r. side of tbeaf, 1. car, along outer border of both hands and both little fingers, within a few m. after taking the medicine (pains in the head» body, and extremities occur oftener aiul more iiirvcrely on r. side; many pains appear on the 1. side, but they are less severe and lasting ; the pains proceed trom r. to I. ; many symptoms appear at n., while in bed « passive movement of the part while sitting or lying always aggravates, it renden the pains more peaeptible, and reproduces pains which had di-appcared j a state of rent seems to favour the action of tnis remedy, as the symptom.^ appear during rest and at n., and are worse during rest, whereas ihey arc ameborated and leave during actire motion ; better after rising until noon, and from 4 to 6 pjn. ; however badly be feel*, the open air will dissipate all his unpleasant symptoms. The action of the remedy is materially influenced by the condition of the mind, and is affected or retarded hy care, grief, anxiety, &c,). •' On Feb. 17th I took 6 gr. of »x trit. : in course of next ^ d. I was in close attendance upon a severe case, which caused roe great anxiety ^ during this time I did not experience a single symptom, but as soon as my anxiety was relieved, the sj-mptoms appeared as regularly and even more violently than before." The pains which he has at n. while lying on the 1. ride arc relieved by lying on the r. side; steady pressure sometimes relieves the pains. Chest, stomach and abdomen are covered with a fine, bright red eruption, consisting of innumerable points, but appearing as a universal redness, pitting and disappearing after pressure, but returning when it has been removed j a painful pimples appear on and joint of the r. thumb, and remain several d. ; itching and burning pimple on r. scapula nrjr lower border, which, after scratching, becomes exceedingly sore and painful (at n. in bed) ; pimple on r. side of septum narium, sore and painful for several d. j itching without eruption ; itching rather increased by scratching; universal itching, not relieved by scratching; itching on various parts of body; nightly itching; persistent itching spots over whole body, following each other in rapid succession ; very troublesome itching over whole body in daytime j very troublesome itching all over body, at n. j •■rxcessive itching, especially of chest, abdomen, back, and hips j the itching in d. and Lc. is not relieved by scratching, but at n. in bed scratching relieves ; itching is woru LbI n., and especially while in bed; pricking pain on povterior surface of^r. thigh, Eremoved by rubbing and scratching} fine pricking pain in bend of the I. knee>joint, • causing him to scratch at n. ; sharp stinging on back of r. hand } sharp stinging on dorsum of large toe of I. foot; itching behind r. car at n. in bed ; itching on variotis parts of r. side of face, at n. in bed; itching on r. buttock, at n. in bed ; a small Itching spot on r. cheek, which he has scratched, pulsates and atings as if fVom needles (f b.) ; persistent itching on r. ->ide of chest, about 5th rib, disappears after scratching ; ncnistcnt itching on r. side of neck (at n. in bed) j persistent itching on

ristcrior surface of 1. elbow (at n.) ; pricking-itching in r. axilla; stinging -itching on scapula as if Jagged with a needle (6 h.) j stinging. itching on external border of r. foot, relieved for a time by scratching, followed by itching on r, leg above ankle; stinging.itching on r, knee, and afterwards on 1, foot, at n. in bed. Slept very well after I a.m., wakefulness till then ; he awakens early in m., and cannot sleep again j I •ftleeplessness without restlessness, lies awake quiet and calm, not being able to sleep { Lhe dreamed that he was proving the drug, — this was followed by a seminal emission. Burning heat in nape of the neck and occiput (5 h.). {Ibid.)

  1. Dr. KeyeSj perfectly well, counted his blood-corpuscles (red) and found them up to his usual average (4,775,275). He then took gr. ^ of mere. iod. 3 times a d. for two weeks, beginning Sept. 1 0th. On the 10th he found the corpuscles 5,572,200 in number. On the 24thj having been up greater part of n. with a patient, and feeling no appetite for breakfast, they were 5,I75>875. Next d., having slept well, and appetite returned, they were 5,562,062. (Amtr. yourn. of Med, Sc.^ Jxxi, 36).

8, Same gave to a patient with chancroid gr.j of same daily for 4 mo. At enaof time his corpuscles were 5,365,125 (average being (5,000,000). Three weeks later, dose having been gradually diminished to gr. I, they were 5,302,375. {/5/V,)

IIL Experimtnts on animals, — I. a. 5j was administered along with food to a pointer dog at 4 p.m. The consequences were, — vomiting, with black semi-fluid alvine evacuations in course of n. ; glassincss of eyes and thick ropy discharge from nostrils by 3rd d. ; and about close of 5th d. prostration, and regular slow motion of extremities to and fro at each respiration. On the succeeding n. the animal died. Up to the last d. he was able to stand, showed no want of appetite, and had not suffered any perceptible sensorial derangement.

b. Dissection exposed to viewed a half decolorised coagulum in 1. ventricle of heart, and a little dark semifluid blood in r. , strong prominent corrugation of lining membrane of stomach, with redness of apices of rugrc, dotted red patches at sides, and a string of extravasated blood in every furrow. (Cogswell, Iodine and Its Cotnpoundiy p. 160.)

  1. a. 3] was given to a strong male rabbit at 9 a.m. In a few h. animal voided a copious semifluid stool ^ the d. following he was affected with tremors and debility, and gave utterance to low plaintive cries in course of n. succeeding which death took place. Shortly before this he passed a scanty semifluid evacuation.

b. Lining membrane of stomach was excessively injected about I in. from pyloric orifice, and presented a small quantity of extravasated blood upon its surface. Its contents were soft, blackish green, and homogeneous, as were those of the small intestines. Rectum and bladder were empty. {Ibid.)

Merciirius biniodatus, mercuric iodide, Hg I,.

  1. Provings. — I. A man, a.'t. 22, lymphatic, took every 2 d. 10 ccntgr. of 3X trit. The 22nd d. there appeared 2 boils, one on inner side of middle of I. thigh, the other on 1. Jeg. At same time 2 smaller boils on 1, side of face about malar region and inflammation of a sebaceous follicle on r. check. 18 d. later there was a painful follicular inflammation at level of chin and a small boil on 1. natis. Finally a pustular eruption at orifice of nostrils. (Andrieu, Journ, de la Soc. Gall.^ viii, J40, 1856.)

  2. A man, xt. 30, lymphatico-sanguine, took every d, 20 centgr. of same. On 14th d. a small red tubercle in centre of I. temple, which lasted 9 d. (/W., H^-)

  3. A woman, *ct. 40, stout, lymphatico-sanguine, took every m. 20 centgr. of same. On 9th d., on middle of 1. maxillary region, a projecting pustule the size of a pea with hard red areola. A similar smaller but very red tubercle above middle of 1. eyebrow. A similar tubercle above r. eyebrow. All were gone in the space of a week. [Ibid,)

  4. A man, xt. 25, lymphatic, took every m. 20 centgr. of same. The 7th d. there appeared 2 tubercles of bright-red colour, the size of a large shot, one on 1. temple, the other on 1. side of forehead, a finger's breadth below the commencement of the hair. There were at same time weight and dull pain in frontal region. They went off in 1 1 d. (Ibid.)

  5. A girl, act. 5, took every m. 5 ccntgr. of same. On the 13th d. there appeared 2 boilSj one on the front of 1. thigh about its middle,

VOL. ni. 18

the other on the inside of 1. leg. TTie 15th <1. a stye appeared, (Ibid.)

  1. A woman, aet. 30, lymphaticoncrvous, took every m. and c. 10 centgr. ofsame. 1 he first 6d. she had great weakness of stomach, accompanied by much weakness of limbs, which came on after each dose and lasted about 2 h. From 7th to 14th d. no symptoms, but on i5ch d. she had great heaviness in hypogastrium, with a feeling when she walked as if something would come out of vagina. The uterus in fact was so much prolapsed that it projected from the vulva the size of an egg. At same time drawing pain is more severe ^ the womb was enormously congested. The medicine was discontinued, and 12 d. later the womb had resumed its ordinary size ; but it was considerably lower than normal, though all thesymptoms had disappeared. (/A/V, 146.)

  2. A young woman took 3 gr. of 2x trit. three times a d. After 4 d. following symptoms occurred, in order as recorded : intense shivering, followed by feverishness \ pain on pressure at epigastrium ; painf^ul swelling of tonsils and submaxillary glands ; distension of abdomen about navel, with pain at that part on pressure; loud and bitter belchings ; hot perspiration ; nausea, while passing a diarrhceic stool ; frightful dreams ; aching pains from hips to ankles, as though she had walked many miles, felt more particularly in bones ; catching pain under r. breast, oppressing breathing ; urine thick and dark when passed ; frequent desire to micturate, she cannot hold her water fur a minute; bitter taste; profuse flow of saliva, and aching in teeth of lower Jaw; hot and inflamed state of r. side of nose, with coryza } feeling in forehead as if head were bound round with tight cord ; pains in bones of head, chiefly occipital ; low spirits, and disposition to cry j excessive giddiness, everything seems Co reel round her. (Robinson^ Brii, yourn, of Ham, ^ xxiv, 517.)

. [The following (8 — 18) arc reiults of a proving by the Philadelphia Provers* Union, made in 1855, of which we only know that the porencirs from 1 — ^o were employed, and whose only rttord now extant is (he schematic pathogenesis given by Hcring.]

Dr. Armor. 111. humour and lilimy taste on waking in m. Slight headache in region of compariiion (3rd d.) Dimnct>k of slight (ist d.). Fine Minging in teeth at times (7th d.) j salivation (5th d.) j large flow of water in mouth ( jrd and fth d.), not so much, but obliged to expectorate (8th d.). Hawking and spitting of small quantity ot white, tough expectoration through d. (and d.) j disposition to hHwk,!ienMtlon asof lump in throat, with disposition to hawk it out all rth d., hawked up a hard greenish lump on 8th d, i sore-throAt, fecUas if&calded on waking, wor^e during empty swallow, ing, all d. quite irouble&ome (6ih d.); v>re-ihroat, worse during empty deglutition (}rd, 4lh, 7lh, and 8ih d.). Nausea and sure.throat alter ^ h. (ist d.). Pain around umbilicus (lit d.). Urine red (md and jrd dj. Hoarse and hu^ky \ h. after getting a little wet in a shower, in t. (5th d.). Cough, with a little loose, whitish, &liniy expettoraiion through d., and with slight difficulty of breathing (loth d.). Cough with white, thick expectoration, became dry in c. (iilh d.), better afterward*, but prevented him from making another proving \ breathing morr difficult than usual (9tU d.). On waking, Mitfnes^ and pain in neck, in rrgiunot i»t or and cervical vertebra, going off in >hori time (+th d.)- Wcaknew uf knee-joints (i>t d.). Fooliih dreams (3rd tl.) ; dreams about gunning and fanning (7th d.), gunning and travelling (1 tih d ) i anxious dreams (itid d.), about rtmoving and hi* relations (4lh d.). Chilly and aching in lower limbs, through forenoon (mdj.) j flushes of heat, and tickling scmatiun over face [\y,\ d.) (Heriho, Mat. Mr./ ^ %ol. i.)

  1. Mrs. Aruok. Pain m forehead ^iM J.). Eyes watery, took slightly swollen.

*7S

Running from nosf, with a good deal of sneezing (tnd d.). Tongue constantly dry, with desire to wet the mouth. De*ircto drink, but small quanlitie-s. Loud rumbling Id bowcU (»nd d.). Pulse accelrnttcd, beating utiongcr. An almost insupportable pain and aching in lower lirobj, in e., better on moving, disappearing during a walk (and d.). Chilliness at bedtime, folluwed by flush of heat over face (!« d.) ; flush of heat and »mation of being tiikled over the whole body (4th d.) j flushes In face, face hot and hands cold. (^Ji/iJ.)

  1. Mr. KoTTNER. Ifritation of mucous membrane of nose, causing constant snuffling {i h., ist d.). (N'U)

  2. Dr, J. R. CoxEjjun. Severe headache all over, from 8 p.m. on ist d,, and all and d.j sharp pain in Mncipur, over both eye»(ti a.m., ist d.). Ej« inflamed, r. eye worst, bright light irritates greatly ( 3rd d.) ; r. eye inflamed, and flight lachryiiiacion(istd.)i pains in and over 1. eye (ind d,). Much saliva in nmiith (4rh d.1. Throat slightly sore, disposition to cough (istd.)) quite sore and inflamed, cough frequent, and expectoration more than usual {2nd d.) ; 1. tonsil inflamed and swollen, velum elongated, which secm^ to cau« coughing (3rd d.) i both tonsiU swollen and inflamed, and velum the same (4th d.) j not so much, but headache very- severe, un jih d.i lessening on 6th d. Occasionally pain in chest or heart, mo^t on l.side (5th d.); constriction across chest (6th d.) ; stricture across chest, most p;iinful I. side (4th d.) i pressing pain acros!^ chest (5th d.); nharp cutting pain in chest, and sticking pain m heart (8ih d.^. Feels weary, and a sort of aching as if bruised in whole body i+th d.). Could not sleep well, very restless, headache. (IhU.)

  3. Same proved on a woman. Pain in head, and flight pain in throat and I. eye (10th to 1 2th d.) i pressure in head, and pain in chc-st (mo>t on 9th d.) j prcssivc pain in head, all d. j dull pressing pain tn lorehead and I. side aI 9 p.m., drawing and sticking at lo p.m. ( ist d.) ; dull pressing pain in forchcail, most severe in r. side, cunt nuing at intervals from 7 to 10 p.m. (znd d.), with sticking pain in heart, till 9 p.m. (3rd d.)i slightly, 3 p.m. (4th d ) ^ pain in forehead and heart (6th d.) 4 pressing. stitching pain in forehead, throat, I. e)'c and 1. check (7lh d.) ; prc&sing.stiiching pain at sides of head, just above ears (4 p.m., 4th d.). R. eye mucn inflamed, blood vesMrU injected (ind d>) ; both eyeti, r, eye weeps greatly (4tli d.) } still inflamed, and weeping, while both eyes pain (6th d.) i at hing pain in I. cheek and eye, which appears slightly inflamed (Gth d.) ; albuginea considerably inflamed, and same pains (8ih d.). Sticking pain in throat (6th d.). In the waist, 1. ^ide, sore feeling on bending. Aching pain across chest (lolh to itth d.). Dull arhing pain in heart (loih to nth d.) ; shooting pain in heart (all 7th d ) ; sticking pains wither without hcadathe (ind, 3rd, and 5lh d,). Sticking pain along I. side of neck and in heart, continuing till she fell asleep (7 to 10.50 p.m., 4th d.) } severe pain in back of neck, as if she had been struck (7 p.m., 5lh d.). {IhU.)

  4. Dr. SiEMERs made five proving^. Good-humoured, even merry, though head is worse (lath d.) j ill-humour about little things in m. of md d.,n'jt on 4th d., again un 5th d. DulneHs in head, occurring often in course of proving, in afternoon j didncss ot head, and slight pressing pain on I. side, as during a coryza (8th d,), relieved by walking in air (loth d.); dull patn in I. hulf of brain, with sensation in anus as of piles ^4th d.) ; every d. some headache ; in m., heatlache, dtsapjitaring with a cor)'za which cea!>es at noon (lolh d.) \ on 6th d., headache at n., continues in m., later only r. side, congestion as with a cold, in afternoon changing <<ides, next d. still more congestive, during e. x. side only, of unusual continuance till late, towards m. oi 8th d. same in bed, less after rising, better 9th d. j headache while sitting still, alter sleeping during d. (ind d.) ; slight pressing pain in 1. brain (6 to 7 p.m., 3rd and 4ih d.) ; pressing aching in head and ear (7th d.) ; headache, I. side (ist d.) ; headache, attrr aw hilc onesided, goes from r. to I., disappears alter dinner (jih d.) ; on waking, pressing headache 1. side, di»appeaiing in c. (nth d ) ; several small pimples on hairy scalp, without itching, containing some pus, and forming crusts {7th lu ^(b d.); small pustules on head (is^h ^ncl t^^^ t^O' ^ V'*^^ '" '■ ^unm-orbital bone he had once bdbre returns (and d.) ^ eyelids affected by the catarrh (8rh d.). [This prover (and he only) had a series of l.ymptom^ referable to hearing, but as one of them is ** hearing as usual dull tn the morning," he would seem to have been labouring under (probably catarrhal) deafness, which would explain— and vitiate — his singular expeiicnces.l Much nasal catarrh throughout proving j also toothache, to which he italc» he is nablc. On point of tongue a small blister (md and 3id d.); scalded

•ennition of tongiie i h. afttr bi-cakfakt (i«t, 7th, and 12th d.) ; MitKaiion in inoutli as if there were fibre* in it (lotli d.) i soreness iniide I. check (and d.>i tmtarioD of being burned in month (forenoon, i4ih d.); laste right, but flabby (6th d.) ; pappj ta";tc, but :i good appetite (5th and 7th d.). Phlegm in throat ; much phlegm m throat and no^c {8lh d,), hawking it out ot throat (loth d.); throat and noMriU dfy. Inclination to have the food more waited (lath d.) ; heartburn after dinner (1 5ih d.) | squcami»bness during meals !ieveral d. Pain in stomach (10 a m^4Jh d.) Pam in r. hypochondrium (yesterday !n I.), with drawing Kenxation in anus as if hemorrhoids were coming ( I n. after doKr), coniinurd somewhat till 6th d.j tran<iicnt drawing uainK in 1. hyporhondrium, afterwards a lame sensation there (m,, Sth d.) ^ sprain* like pain in r. hypochondrium, near pelTi!> (13th and i^-th d.) ; kuddcn cutting pain in region of liver (14th d.) ; rumbling in abdomen (loih d.) j pain in abdomen as before a stool (e., 7th and 9th d.) i in m. after good night's rd^r, pain as if sprained in r. pelvic region, towards ba«-k,it disappeared while walking (5th d.). Diarrhcra in m. ; soft stool 6th and Sth d. j 4 firm stool&in }4h.,moreat n. (loth d.)' Prewing bearing down on bladder (3rd d.)^ st-nsation in urethra as if the urine were hot, during normal Ktool in m. (5th d.). Sen\itiveness of r, testicle and spermatic cord (towards a p.m., 3rd d.). Voice veiled and rough (Sth d.) j hoane, with coryza (7ih d,); spelts ot cough during d. ($th to7thd.)j profuse ycllowi^h expectoration (loth d,). During a w:ilk, sudden sticking in muscles of chest, I. ilde, exactly on spot where, a years before, he had commencement of aciJte rheumatism (iith d.) ; stickmgpain in mu<tclc^ of ribs, I. side, after walking out during thawing weather (9th d., somewhat the same loth d.)' Rheumatic pain, for short time, in muscles of neck and back of neck (6ih d.) ; pain in os coccygls, ist, 3rd, and Sth d., like a pain he had before proving. Siiffhess of limbs, better after walking (9th d.). Rheumatic pain in r. knee and hip, during forepart ot d.j disappeared latter part of d. (19th d.) j pain in I. hip-joint as if spraineti (9th d.) j feet are painful (6lh d,), particularly soles (7th d.) ; pain in Sail ot foot and large toe, relieved by walking (10th d.) j taward<> m., pain in r. big toe, like podagra, but without ^welling and redness, it disappeared after rising (3rd d., returned 6th and jih d.l ; sore pain iKtwcen toes oi r. loot (19th d.). Painful itching on several parts of skin of r. forearm (9th to iith d.}. Deep sleep, afternoon, several d. in sucression ; quarrelsome dream^. (7W.)

  1. Dr. Pehrson. Great heat in vertex, only ohjeciJve, all d. ; at it p.m. frit it very hot, and a hlight puUation in it (6th d.). Increase of saliva, almnr noon {6fh d.). Weakness in bowels and stomach, partly extending into chest, from 6 a.m. till 3 p.m., tecling as if he would have a stool; during tht-t time had to belch up wind frequently (ist d.). Easier stool, and not so thick as usual (and and 5th d.). Awoke from feeling of great soreness in whole breast, but only fur a few tn. (4tb d.). Synovial inflammation of I. index; on snd d., about 3 p.m., a pricking-itching over r. hand, lasted I h., followed next d. at 6 p.m. by itching pricking at lower part of upper arm, all round it, lasting ^ h., and same sensation in upper part of upper arm, mostly in armpit, lasted only tew m., — all this on r. side. (IbiJ,)

1$. Dr. Nerendank- Eye^ inflamed, particularly the r. (8th d.). i6. Symptoms obtained by Drs. Miller and Pavne, discrimination being Impossible. (Sec Hcring*K list of sources.) Heaviness in head, with soreness over the bowcU(i3th d.) i dull heavy pain in head (5th d.); pain and heat in the head; fulness m head (md d.) ; headache, worMr in forehead (4 p.m., 7th d.) j headache, panicularly in afternoon and e., with a drowsy stolid feeling in head (3rd d.) ; violent Headache with nausea, from m. till a p.m.. returns in c., particularly in forehead (aist d.); dull heavy aching pains at base of brain, throat, and nouriU (latter dry) ; after 1 gr. ot tnd trlt., taken in e., slight heavy feeling right through forehead up to vertex, also same sensation outside ttkull, next d. heavy feeling m forehead all d., more severe than d. before, and in e. with severe throbbing In r. side of head, from front to vertex i «.light heaviness, and in ahernonn slight throbbing from vertex to nose, r. side (6ih d.) ; headache r. side, disappearing alter rising ; heavy feeling out. Hide of skull. Eyes much inflamed, and burn (11st d.) ; burning in forehead at z p.m., eyes bum and arc inflamed till 10, next m. better (4th d.), less inflamed, but weak and hot (9th and loth d.), this rerumed (i4fh d.) A cold in head, divappeir. ing in open air, but returning in a warm room, with it a cough from irritation (i«t d.). Heavy dull aching in upper jaw, then in lower, mostly on the Mdcs, worse r. ; he pressed the teeth so much during sleep that the muscles were tired and lame on

wftkbg; pain in jiws and temples (7ih d.)- During dinner pain in all the tctrth f'ram mastication (8th d.) ; the gum of the upper jaw over ?>econd r. muUr excessively tender, a& if an at)sce^s na^ forming, continuing 4 d.j on 6th d. it had entirely diuppeared without forming an abscess; unusual flow of saliva for the finJt 11 h., salivation returned later again, with constant decided metallic taste; in e. (after ind dose in m.) rocnllic taste and ta^te of iodine j gums feel sore, as if he was going 10 be ulivatcd. Slight superficial ulcers in throat, in patches.; almost constant desire for empty deglutition, apparently from large collection of water in raouth, and frum sense o! fulness in throat ( jnld.); during eructations pain in region of r. parotid gland for 2 h., for a+ h, there was soreness to touch there. Nausea and sinking at eptga%trium, with general sick feeling (J3lh d.) ; squeamishness of stomach, with uneasiness and laziness all over limbs, with rheumatic pains, inclination to vomit, and constant strong desire for stuol. In region of liver, pancreas, and spleen, heavy painful sensation, which does not continue all the time fijth d.) ; aching and full feeling in r. hypochondrium (3rd d.); sensation like threatening colic, e. till fully asleep (i!>t d.). Frequent dcMre to stool, with pain in abdomen; ■notion in abdomen, and urging to stool, without stool, from 11 p.m. the whole n. through (13th d.); pain in abdomen, with diarrhoea, from 11 p.m. the whole n. through (loth d.). Severe griping and colic pains, forcing him to stool, followed by a very large, copious, but nut loose discharge of rather a light-brown colour, could not pavs any urmc xs long a^ discharge lasted, after discharge urging; for evacuation continued, with irritation and itching in rectum and anu^, which felt as if it wuuld

f»rotrudc i about 11 again had severe colic pain**, which left him after a pretty loose, ight-ycUowish brown, somewhat watery discharge, coated with mucus, and of slight bloody appearance ; after the discharge a slight tenesmus existed for a time, but colic pains disappeared more and more, only great soreness oi the boweU remained i after dinner (a p.m ) colic pains again returned, with a thin, loose discharge, and slight tenesmus} in afternoon and e. only a sorenesis in bowels. Incivased now of urine (3rd, 4th, $th, and 6th d.). In attcrnoon he felt several times sharp shooting through r. ^ide of chest, like rheumatism, going down arm. Aching and stiffening feeling in r. splcnius capitis (3rd d.). Rheumatic shifting pains, general in limbs, and mostly muscular, alternately in arms and hands, legs and feet, occa.>iunaliy pains of like character iu 1. ear, xs if it would be a violent and long-continued otalgia, it lasted only for a niumtnt at a time, but fretjuently returned (13th d.). Rheumatic nains, soreness and stiffness, in 1. arm, worse by motion and during middle of d., l>etter in e., and at n. could lie on the arm i rheumatic pain — more in r. forearm and hand, with sense of great weakness, at n. pains got so violent as to disturb his sleep } dull, aching, strained sensation in middle o\ os humeri as if about to break, wavering stitches through all the muvcles, and sensation as if they were sore, desire to stretch limbs and body ; aching and drawing pain in bones of 1. forearm; jerking in fingers of I. hand in e. till he fell asleep. At 8,30, when walking, acute pain passed through and around head ot r. tibia at knee-joint, in 3 or 4 successive throbs, passed off in 5 m., returned in same degree and form, and at same time came in r. parotid gland ; \a

4 h. pain in knee disappeared; 1 throbs of a like pain fell in 1. rectus femoris, and in

5 m. renewal of similar pain in same place (13th d.). Weariness in m,, all d. sore pain in 1. fmgers (1 d.); from midnight till m. very restless feeling, with constriction ra diaphragm almost like cramp. Nearly a month after rhe other symptoms, several d. after ixth dose, a small pustules on outer side of r. leg, jubt below knee, about a in. apart, •slightly itching, sore to touch, with inflamed bases; on 3nl d. after their appearance they scabbed over, but matter continued to accumulate under scabs ^ they were quite sure, and were not healed till 1 3 d. afterwants ; later, another sore of same character appeared in front of same leg, below knee, which healtrd in 3 d., and no mure appeared. A wen which had existed behind r, car from infancy, in a young woman of 34, burst open and discharged 19 d. after 1st duse, and 11 d. after last dose. Very strong itching on neck and dorsum of hands, particularly on fingers of r. hand (ijih d.). Very sleepy and drow%y in e., with s(|ueami«hness of stomach and great uncaiiness and laiiness all over limbs (5th d.) ; sleep disturbed by troublesome dreams, such as swimming and wading in water, and pushing through low places, and under a shed; half conscious hleep with fearfulncss,drcinied of detecting robbers in n. attempting to enter dwelling ( tath d.) j dreams a great deal (1 ith, tzih, and i}lh n.). Sometiino a chilly feeling and creeping sensation all over skin, and uneasy

sore feeling all uvtr howrls j often firit chilly, and then inin quite wmnn, lUthcnigh his pulse was natural (intl d.) ; felt pretty warm all over, but not feverish, fiutnetimes a chilly feeling, and creeping over the back. (lifiJ.)

i7« Dr. Raue. Dull pressure in cerebellum below occipital protuberance, after awhile pressure over eyes (from inhaling the vapour). Almost con<(tant drsinc for empty deglutition, apparently from large collection of water in mouth, and from sense of fulness in throat (3rd d.). {IbiJ.)

  1. RiBsEBERO. fFrom external application to forehead.) Dull, rending, tear* ing, giianing pains in lorehe;4d, worse during n., disturbing sleep (3rd d.). Skin on forehead pale reddish colour (|U d.), dtrty grey (jth d.), afterwards quite full o( the finest wrinkles, peeling oft' in small scaleft atter 7th d. ; numerous Mnall cracki and rhagades in all directions on forehead. {IbU.)

Ill, Experiments on animals. — i. A strong male rabbit took, at 8 a.m., 3] along with its food. In the progress of the d., the animal graduaJIy became much enfeebled, evacuating the contents of the bowels, and on the following m. life was found extinct. On examination, the inner surface of the stomach was seen occupied, for about the space of an inch near the pyloric orifice, by some of the poison mixed with vegetable matter, which mere washing with cold water would not remove, while the immediate neighbourhood presented a crowd of minute yellowish elevations. The genera! surface of the inner membrane was prcternaturatly reddened. (C6t;sWELL, op. cit.)

  1. I ogr. were dissolved injjssof watercontainingSjofhydriodatcof potash, and the whole of the fluid was administered to a large, young Newfoundland dog. The animal manifested strong dislike to the taste and in 4 or 5 m. vomited a quantity of frothy mucus, with violent retching, which was repeated about four times within the h,, the last matter brought up exhibiting streaks of blood. During this time great uneasiness was indicated by constant changes from the standing to the lying posture, and the reverse ; and after several attempts to relieve the bowels, the animal succeeded in about | h. in evacuating a loose stool. The whole of the following d. was spent in a state of marked depression, after which he began to take nourishment, and in 4 or 5 d. seemed to be not at all under the influence of the poison. {UU.)

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