Antimon. Et Potass. Tart
Tartar emetic, 2 [K(SbO)C4H4O6
By Timothy F. Allen — The Encyclopedia of Pure Materia Medica
] H2 O
Preparation , Triturations.
Authorities. [Symptoms in Stapf (Archive, 3, 2, 146), from Shæfer, Hufel. J., 1810, are omitted , being observed after tartar emetic given in canelle water; also Schœnfelder, do; observed from a solution of antimony glance (crudum) in acetic acid; also Goodwin, do., from tartar emetic mixed with camphor; also Barbier, see Hencke's compilation, A. H. Z., 88, 5, tartar emetic mixed with chicory; also Jankovich, do., from tartar emetic mixed with opium.]
1 , Hartlaub and Trinks, Reine Arznei-mittldehre, 2, 209; 2 , S. Hahnemann, Archive, 3, 2, 146; 3 , Rückert, do.; 4 , Gross, do.; 5 , Stapf, do.; 6 , Fr. H-n, do.; 7 , Hering, Archive, 13 z., 183; 8 , "M.", in Buchner's review, Hygea, 18, 274, took first dil. repeated doses; 9 , do. took one grain at once; 10 , Molin, Comptes rendus du Congrès Méd. Hom. d. Paris, 1851-56, proving with sixth and eighteenth dilutions, repeated doses; 11 , Nœbling, N. Z. f. H. K., 14, 80, proving with several small doses and subcutaneous injection; 12 , Bœcker Beitrage, crude proving; 13 , Mayerhofer, in Bœcker Beit., effects of one one-hundredth of grain; 14 , De Moore, Rev. de l. Mat. Med., 5, 436, proving with one-quarter grain; 15 , Macfarlan, Am. J. Hom. M. M., 4, 60, prov. 3m Fincke; 16 , Woodbury, N. E. Med. Gaz., 4, 238, four grains a day for fifteen days; 17 , Giaccomini, N. Archive, 1, 2, 107, one scruple; 18 , Hutchinson (in Stapf's collection, Archive, 3, 2, 146, effects of inunction), (see also Wibmer); 19 , Blackburne, do.; 20 , Horst, do., inunction (Hufeland's Journ., 1813); , Bonetus, do.; , Elias, do. (Hufel. J., 20), eight grains in a clyster; , White, do.; , Bæumlinus, do.; , Stutz, do. (inunction); , Autenrieth, do. (inunction); , Hecker, do. (inunction); , Walther, do. (four pounds in milk, the curds eaten by two students); , Serres, from Hencke's collection, A. H., Z., 88, 5 (and also from Wibmer); , Troschel, do.; , Driver, do.; , Male, do.; , Duffin, do.; , La Clinique, do.; , Med. Gaz., do.; , Wetzler, do.; , Krebs, Hygea, 20, 289; , Hildebrandt, do.; , Imbert-gourbeye, Brit. Journ., 19, 367, et seq ., eruption from inunction; , Bœckh Frank's Mag.; , Lembert, do.; , Crichton, do.; , Wesener, do.; , Schneider, do.; , Carron, from Wibmer; , Orfila, Toxicologie (from Roth Mat. med.); , Recamier, do.; , Constant, from Roth; , Savory, do.; , Sachi, do.; , Baumbach, do.; , Freer, Lancet, 1847 (effect of two drachms); , Harley, Lancet, 1846 (effect of ten grains on a child); , D. Kiger, O. M. and S. Rep., 5, 171 (child swallowed one-half ounce crude).
MIND
- Furious delirium (third day), 47.
- (Suicidal mood; he raves and does not know what he is doing), 2.
- Excitement of disposition, 11.
- He was talking to himself, 47.
- Despondent and apprehensive about his recovery, 16.
- Hopeless, despondent mood, toward evening , with chilliness, pain in the chest, and great sleepiness, 3.
- 4.30 P.M., very morose, dejected, and sad, 1.
- The anxiety increases with the nausea , together with a slight pressure and some warmth in the abdomen, which moves about with the free flatulence, 5.*
- She is frightened at every trifle, 2. [10.]
- Apprehensive, with fulness about the heart and increased warmth (eighth day), 8.
- Apprehensive and restless, 4.
- Dreaded to be left alone even for a few moments, lest he "should be dreadfully nervous and not know what to do with himself," 16.
- Bad humor, everything goes wrong, 10.
- Bad humor, noise is intolerable, 10.
- Everything displeases her of which she thinks (after two hours), 1.
- Peevish and quarrelsome, 54.
- He rubs his eyes with his hands as if in a stupid sleep, and wakes in a very ill-humor, e. g. , if one looked at him he began to howl, 5.
- The child will not allow itself touched, without whining and crying , whereby the toes and fingers are drawn inwards, 2.
- The whole time an unusual, noticeable (more to others than to herself)
wild gayety, toward evening ; this gave place to fretfulness, peevishness, and anxious thoughts about the future; she thinks she will remain in her present condition, 3. [20.]
- Excited mentally (ninth day), 8.
- Restless, excited mind, 13.
- Became senseless, 17.
- Loss of consciousness; he falls into a state of stupor, interrupted from time to time by spasms, 50.
HEAD
- Head confused (second day), 8.
- Head confused, 9.
- Head much confused (fifth day), 8.
- Head confused in the morning , which disappeared after rising (first day), 8.
- Head confused, with a warm forehead, depression of vigor, and indifference to everything, 36.
- Confusion of the head, like a stupefaction, with a feeling as if he ought to sleep, 4.
- Head confused, with heaviness and pressure in the forehead (eighth day), 8. [30.]
- Confusion of the head, like a pressure in the temples (immediately), 3.
- Marked confusion of the head, with increasing nausea, 5.
- Head heavy, confused, 13.
- Head heavy, much confused (ninth day), 8.
- Head heavy, pressive, and confused, 17.
- Head heavy, confused, with great discomfort on waking, mornings (ninth day), 8.
- The head is heavy, confused, and painful, with internal heat in the head (3 P.M.); it becomes better in the open air, and does not return again in the room, 1.
- Vertigo, 11, 12, 13, 17.
- Vertigo (eighth day), 8.
- Attacks of vertigo (third and fourth day), 3. [40.]
- Vertigo often on closing eyes, 12.
- Vertigo on walking; he totters, 2.
- Vertigo, with flickering before the eyes (third day), 3.
- Whirling in the head (ninth day), 8.
- On trying to lift his head he felt a dizziness which obliged him to replace it on the pillow, 45.
- Dulness, dizziness, 18.
- No pustules, but an inflammation of the meninges of the brain; the patient ran about delirious (inunction of four grains), 37.
- Congestion to head, 13.
- Headache, 2.
- Headache (second day), . [50.]
EYES
- Squinting eyes, 53.
- Enlarged, swollen eyes, 10.
- Bloodshot eyes, 45.
- Weak and dim eyes, 13.
- Weakness of eyes (eleventh day), 8.
- Eyes feel so tired that they would close, 4. [130.]
- Burning in the eyes, evenings, as if he had studied long by the light, 4.
- Pressure on both eyes, 5.
- Sense of weight on eyes, 10.
- Inclination to press the eyes tightly together, 4.
- Dull pressure over the nose and one eye, 4.
- Violent tearing between the root of the nose and the right eyebrow, as if some one took hold of her there by the skin; very painful and long-lasting (after half an hour), 1.
- Difficulty of moving the lids (second day), 39.
- Sticking, like electric stitches, in both inner canthi, and pressure in the eyes, 3.
- Burning and biting in the right internal canthus and redness of the conjunctiva, 5.
- Acute conjunctivitis, with much lachrymation, 15. [140.]
- Yellowness of the sclerotica, 10.
- The eyeball pains as if bruised, especially on touch, 2.
- Sudden, rather severe, tensive pain in the upper part of the right eyeball, 5.
- Vanishing of sight (ninth day), 8.
- Vanishing of sight and hearing, 9.
- The sight vanishes when she looks at an object for a long time, 4 1/2 P.M., 1.
- Sparks before the eyes, 11.
- Flickering before the eyes, 8, 11, 13.*
- Flickering before the eyes, especially on rising from sitting, several times in an hour, of short duration; she sees only as through a thick veil , with vertigo (several days), 3.
- Blackness before the eyes, , .
EARS. [150.]
- Twitching-tearing in the right concha, in the evening on lying down, which disappears in bed, 1.
- Ulcerative pain in the right concha, in the evening (after two days), 1.
- Twitching, painful tearing in the right ear, in the morning (second day), 1.
- Roaring in the ear (fourth day), 3.
- Fluttering before the left ear, as from a large bird; at the same time a warmth passes to this ear, as if she stood near a hot stove; gradually disappearing (after one and a half hours), 1.
NOSE
- The corners of the nostril are ulcerated and painful (fourth hour), 2.
- Nose pointed, 17.
- Violent sneezing, five times, 13.
- (Twice hearty sneezing), 4.
- Sneezing, fluent coryza, and chilliness, with loss of taste and smell, 2.* [160.]
- Fluent coryza, 2.
- Fluent coryza and tickling cough, with violent eructations, retching, and vomiting of a tough, watery mucus (eleventh day), 8.
- Catarrhal symptoms toward evening (eighth day), 8.
- Catarrhal stoppage of the nose, with thick, mucous discharge, 1.
- Catarrh in the left nostril, with stoppage of the nose and loss of smell (1.30 P.M.), 1.
- Now stoppage of the nose, now a fluent catarrh, 1.
- Nose-bleed at 3 P.M., followed by fluent coryza, with sneezing, 2.
- Stupefying tension across over the root of the nose, as if laced with a band, 4.*
- A tearing and crawling in the left nostril, as of sudden irritation to sneeze, which, however, does not occur (after half an hour), 1.
FACE
- Red face, 45. [170.]
- Face bright-red, 34.
- Face smutty color, 12.
- Livid face, 50.
- Pale face, 17.
- Great paleness, 10.
- Remarkably pale face, for an hour, 5.
- *Pale, sunken face, 11, 12.
- Face unusually pale, and wore an expression of extreme anxiety, 16.
- Countenance livid, bathed in clammy sweat, and expressive of great suffering (one hour), 52. [180.]
- Cold sweat on face, 10.
- Spasmodic agitation of the facial muscles, 48.
- Convulsive twitches in almost every muscle of the face, 19.*
- Countenance distorted, with peculiar tetanic spasms of the jaws, as though she was endeavoring to bite everything within reach, 53.
- Burning heat of face, 11.
- Tensive feeling in face and neck (second day), 39.
- Dull pressure on the left malar bone, 4.
- Sensitive drawing, at last dull pressure, on left malar bone, 4.
- Lips livid, 17.
- Cracked lips, at night on waking (fourth day), 3.
- Dry, scurfy lips (third hour), 2.* [190.]
- The right and left sides of the upper lip are full of clear, itching vesicles, which, on drying up, are replaced by new ones; the itching is especially violent in the evening, 1.
- On the right side of the lower lip several clear vesicles; at the same time the right side of the upper lip is swollen and covered with small pimples, with tensive pain on pressure, 1.
- Burning externally on the right side of the chin, which lasts but a short time (after one hour and a half), 1.
- Burning on the right side of the chin, as if one held a hot coal to it (after one hour and three-quarters), .
MOUTH
- Violent toothache in the morning (fourth day), 3.
- Tearing in three to four teeth of the lower left row, which soon disappears (after an hour and a half), 1.
- Pain in a root of a tooth of the right lower row, as if it were being taken out, which frequently returns, 1.
- Gums bleed, as if scorbutic, 33.
- Several burning blisters on the left side of the tongue, which soon disappear, but return a day later (sixth day), 1.
- Tongue dry and red (one hour), 52. [200.]
- Tongue very red and dry in the centre, 30, 34.
- Tongue coated, 12.
- Tongue in morning thick yellow, thicker in P.M., 12.
- Tongue coated gray, 5.
- Tongue thickly white coated, 33.
- Tongue covered with a thick, white, pasty coat, 16.*
- Tongue coated slimy (fourth day), 8.
- Tongue coated pappy, slimy, 13.
- Moist, clean tongue, 19.
- Tongue difficult to move, 12. [210.]
- It is painful to move the tongue about, 47.
- Tearing pain on the left side, behind the root of the tongue, noticed on swallowing, 5.
- In the morning after rising, the mouth is so sore that she can scarcely swallow, with white tongue and sour taste (second day), 1.
- An unpleasant sensation on the palate the whole time, 3.
- On the posterior part of the palate, sensation of soreness, and as if a hard body lay against it; without swallowing; it disappears on eating bread (8 A.M.), 1.
- Itching below the right corner of the mouth, where, after scratching, three vesicles arise; also under the left corner (second day), 1.
- Mouth dry (ninth day), 8.
- Increase of saliva, 11.
- Saliva increased; must frequently expectorate, 12.
- Salivation, 12. [220.]
- Copious saliva runs from the mouth (fourth day), .
THROAT
- Increased mucous secretion in the throat, 11, 13.
- Much mucus in throat and short breathing (eighth day), 8.
- Sharp pain at the throat, 46.
- Choking sensation, 10.
- Roughness in the throat, with sensation as if a small leaf obstructed the windpipe, on hawking; for one hour (after one hour), 1.
- Great roughness in the throat, which soon disappears (7 P.M.), 1.
- Throat raw; swallowing difficult and painful, 12.
- Itching and dryness in the throat, which provokes a hacking in the morning (seventeenth day), 1. [250.]
- The soft palate and pharynx very red, covered with vesicles; many are opened, swollen, and covered with mucus, 33.
- Rapid swelling of the cervical glands and tonsils, 2.
- Sensitiveness of œsophagus, so that unchewed morsels cause much pain, 13.
- Swallowing sensitive, 12.
- Difficulty in swallowing, 11, 30.
- Great dysphagia, 46.
- Deglutition is impossible, 45.
STOMACH
- Appetite increased (second day), 8.
- Canine hunger on walking in open air, 2.
- Though food tastes good and he has some appetite, yet he can only gradually get some food into his stomach, from which he feels better, and the pressure in the abdomen is somewhat relieved (first day), 3. [260.]
- On eating, soon satiated, almost nauseated, must stop eating, 12.
- He eats at noon with appetite, but after he is satisfied a kind of nausea attacks him at times, 4.*
- Some appetite, but food was quickly rejected, 16.
- Usually good appetite, only sometimes poor, 3.
- Extraordinary appetite for apples, and thirst for cool water; evenings he is soon sleepy, against his usual habit, 4.*
- No more desire for tobacco, 7.
- Cannot eat, on account of nausea and aversion, 12.
- Appetite diminished (third day, et seq .), 8, 12.
- Loss of appetite, 11, 36.
- Appetite completely lost (fifth day), 8. [270.]
- Loss of appetite in the morning, 10.
- The child eats little but drinks much, 2.
- Thirst (second day), 8.
- Great thirst, 53.
- Thirst increased (fourth day), 8.
- Urgent thirst, 10.
- Thirst constant and insatiable, 16.
- Much thirst one day, the next none at all, 2.
- Thirst, with internal heat, 5.
- Thirst for beer or sour milk, with dryness in the throat (6 P.M.), 1. [280.]
- Desire for strong liquors and acids, 10.
- Desire for acids, 7.*
- *Absence of thirst, .
ABDOMEN
- Around, below the short ribs, sensitive painful tension, so that he can hardly sit, but would rather lie, from incarcerated flatulence, which passes off from time to time, 4.
- Dulness over the liver, increased one finger's breadth at the base, 11. [390.]
- Epigastric and liver region some what tense (fifth day), 8.
- Liver sensitive to contact, 11.
- Warmth about the navel, gradually extending over the whole abdomen (after quarter of an hour), 1.
- Colic around the umbilicus, early in morning, 10.
- Inflammation of the abdomen, 41.
- Inflated abdomen, 10.
- The abdomen is somewhat distended, and there is gurgling in it, perceptible externally, 5.
- Abdominal meteorism, 47.
- Distension and tension in the abdomen, relieved somewhat by discharge of flatulence, but often returning, 1.
- Upper abdomen distended and painful, 26. [400.]
- Bowels relaxed (second day), 39.
- Rumbling in abdomen as if water were in it, relieved by passage of wind, up and down, 12.
- Much rumbling in the not-distended abdomen, before the diarrhœa, 5.
- Rumbling and gurgling in the abdomen, 22.
- Rumbling in abdomen, after eating, 12.
- Much commotion in the abdomen, soon after taking, 1, 5.
- Slight moving about in the whole abdomen, with fine pinching, as if stool would occur (after one and a half hours), 1.
- As the nausea paroxysmally increases, and slight retching motions arise in the throat, a spasmodic motion is perceptible in the upper abdomen, 5.
- Astonishing amount of flatulence, with rumbling in the abdomen, and only slight griping; the easy passage of it relieved (second day), 3.
- Frequent offensive flatulence, preceded by rumbling and uneasiness in abdomen, 12. [410.]
- Pains in abdomen, after eating, 10.
- Violent pains in abdomen, after vomiting, .
STOOL AND ANUS
- Several painful tearings in the rectum, after dinner, 1.
- Sticking pain in the rectum (second day), 3.
- Transient stitch in the rectum (ninth hour), 3.
- Sudden, violent, alarming stitch from the lower abdomen, down through the rectum (fourth hour), 3.
- (Hæmorrhoids), 2.
- Burning in the anus after stool, 5. [470.]
- Violent tension in the perineum, especially on walking, with strong desire to urinate (uninterrupted for several days), 3.
- In the morning, after rising, the usual stool, with cutting in the rectum, preceded by pinching in the abdomen (fourth day), 1.
- Stool after eating, 12.
- Stool solid at first, then pasty, with tenesmus (fifth day), 8.
- After repeated desire, stool, which seems to be almost thin fluid, but really is only pasty, 4.
- Pasty stool (three in twelve hours), 36.
- Copious alvine evacuation, 44.
- Soft copious evacuation, 10.
- Liquid, greenish stool, with heat at anus, 10.
- Stool, thin mucus, with rumbling and pressure in the bowels (ninth day), 8. [480.]
- Stool soft, half fluid (sixth and seventh days), 8.
- Soft stool every day, for four days, 10.
- In the evening, two soft stools, 1.
- Two thin fluid stools, with sensitive drawing pains in the abdomen (eleventh day), 8.
- Though he had his usual stool a few hours before, yet he is obliged to go again to stool, 4.
- Repeated tendency to stool, 4.
- Diarrhœa, 11.
- Abundant diarrhœa, 48.
- Diarrhœa yellowish-brown, 5.
- Thin, bilious, mucous diarrhœa, 12. [490.]
- Diarrhœa slimy, appears like yeast, with a marked cadaverous smell, 54.
- Diarrhœa is very watery, 5.
URINARY ORGANS
- A very sensitive sticking pain in the lower part of the bladder; he believes that the pain must be caused by troubles from a stone (third day), 3.
- Burning in the urethra while urinating (eighth day), 1.*
- Violent burning in the urethra after urinating (third day), 3.*
- Slight tearing pain in the forepart of the urethra, 5.
- Continued sticking pain in the posterior portion of the urethra, the whole forenoon (second day), 3.
- The urging to urinate and the burning in the urethra increase, only a little urine passes; the last drops are bloody and accompanied by violent pain in the bladder (fourth day), 3.* [510.]
- Increased desire to urinate (ninth day), 8.
- Frequent desire to urinate (eighth day), 8.
- Violent urging to urinate, during which it burns in the urethra (second day), 3.
- (He can hold his water no longer), 2.
- Diuresis, 18.
- Frequent urinating, and pressure to urinary passages, 12.
- Urinates more frequently (fourth day), 8.
- Frequent passage of dark urine (fifth day), 8.
- Frequent urinating, forenoons and evening (sixth day), 8.
- Frequent urinating, followed by relief of symptoms (eleventh day), 8. [520.]
- Increased urination, 11.
- Copious urination, 10.
- Profuse urination, 17.
- Urine profuse (second day), 39.
- Urine increased; clear, watery, 12.
- Urine increased, dark, turbid (ninth day), 8.
- Urine more copious and frequent; diminishes at last, 4.
- Retention of urine followed by fatal eclampsia (inunction), Krebs, 37.
- The urinary troubles last from two to six days continually, at first increasing, then gradually decreasing, 3.
- Urine dark brownish-red, turbid, and with a strong odor, .* [530.]
ANTIMON. ET POTASS. TART. SEXUAL ORGANS
- Sexual organs first excited, then relaxed, 12.
- A burning irritation, very singular, more like a tickling, though not at all voluptuous; rather very troublesome; not relieved by anything; extends from the region of the rectum, through the urethra, to the glans, where the tickling is most severe (lasts six to seven days without interruption, and is his most distressing symptom), 3.
- Sexual desire aroused (eleventh day), 8.
- Leucorrhœa for two days only, 1. [540.]
- The menses six days too early, weak, and only for two days, 1.
RESPIRATORY APPARATUS
- Tough secretion of mucus from air-passages (fifth day), 8.
- Large increase in amount of carbonic acid expired, 12.
- Violent tickling in the air-passages provokes a short cough, 5.
- Pain in larynx, and short cough on talking, 12.
- Fulness and oppression in bronchi (third day), 8.
- Irritation to cough, with tough mucus in the throat, oppressed breathing, and sensitive stitches in the left breast (ninth day), 8.
- Voice small, changed; evening (ninth day), 8.
- Morning hoarseness, 12.
- Hoarseness, worse on talking, 12. [550.]
- Increased hoarseness, with cough, hawking, and expectoration, 12.
- Cough for half an hour before midnight, 2.
- Cough after eating; the child vomits his food and mucus, 2.
- The catarrh provokes a cough, though she had no power to cough, 2.
- Much cough and sneezing, 2.
- Dry, frequent cough, 10.
- Slight, dry cough, 10.
- Two attacks of dry cough (after one hour), 1.
- Difficult cough, with some expectoration, 12.
- At the beginning of every paroxysm of coughing she often snuffed for air, as if she could not get it, before she got the strength to cough, 2. [560.]
- Cough and hawking of mucus in morning; comes up easily, 12.
- Cough about 2 or 3 A.M., with expectoration, 2.
- Sputa white, frothy; expectoration abundant, 54.
- Easy expectoration of a great deal of sweetish, transparent mucus, 14.
- Rapid breathing, 9, 43.*
- Respiration short, 29.*
- Respiration heavy anxious, 9.*
- Respiration hard and anxious (third day), .
CHEST
- *The mucus rattles in the chest; oppression of the chest, 2. [580.]
- Large pustules on the chest and neck, like cow-pox, with a red areola; after three weeks it is covered with a crust, and leaves a deep scar, 25.
- Anxious feeling in chest and around heart, 13.
- Anxious, with oppression of the chest and rising of warmth from the heart, 4.*
- Pain deep in chest and pharynx, after violent sneezing, 7.
- Burning in the chest (before each of his usual epileptic attacks), which rises into the throat, 6.
- Fulness in the chest (sixth and seventh days), 8, 10.
- Chest feels all the time very full, 10.*
- Fullness in lungs, 12.
- Constriction of chest (fifth day), 8.*
- Constriction in chest, frequently associated with cough, 12. [590.]
- Oppression of chest, 10.*
- Uncommon oppression of the chest (fourth day), 3.
- Pain, as if bruised, in the upper part of the chest, on bending the head forward; on rising, it is relieved, but returns on stooping again (after two hours), 1.
- An almost sore, paroxysmal feeling in the chest, especially in the left side, toward evening, the second day, with a hopeless, despairing mood, 3.
- Rawness and constriction in chest, and expectoration of mucus, 12.
- On stooping, a fine stitch on the right lowest rib (after one and a half hours), 1.
- Pain in right side, behind and at base of chest, aggravated by deep breathing, 10.
- An itching stitch on the right nipple (after three-quarters of an hour), 1.
- Burning in the left breast, near the shoulder, more externally; on pressure or rubbing, it is worse; then it diminishes and intermits somewhat of itself (after half an hour), 1.
- Long-lasting painful stitching in the upper left side of the chest, near the clavicle, and at the same time in the left axilla (after two hours), . [600.]
HEART AND PULSE
- Pulsation of the heart small and irregular (fifth day), 8.
- Heart's action accelerated, irregular (eighth day), 8.
- Palpitation (almost), (fourth day), 8.
- Palpitation of the heart, 10.*
- Frequent palpitation, 12. [610.]
- Violent palpitation , with the purging, 2.
- Repeatedly apprehensive and warm about the heart, with violent beating of the heart, so that it seems as though he felt it in his head, 4.
- This whirling and beating of the heart comes on every night regularly, and lasts until he breaks out into a sweat, 2.
- Oppression at the heart (fifth day), 8.*
- Pulse rapid and almost audible; a general pulsating which she believes must be audible to the bystanders (fourth day), 3.
- Pulse somewhat excited (third day), 8.
- Pulse full and rapid, 9.
- Full, rapid pulse, 18.
- Pulse full, accelerated (thirteenth day), 8.
- Pulse full, irregular, accelerated (fifth day), 8. [620.]
- Frequent, irregular, full pulse, 12.
- *Pulse rapid, weak, trembling, 19.
- Pulse 88, 33.
- Pulse full and hard; the skin warmer than usual, 34.
- Slow, full pulse, 50.
- Decreased action of the heart; retarded pulse (after repeated small doses), 11.
- In general, pulse slower and weaker, 12.
- Pulse 10 beats slower, 28.
- Pulse sank from 78 to 60, 16.
- Pulse weak (sixth to seventh day), 8. [630.]
- Pulse depressed, 10.
- Pulse small, contracted, 29.
NECK AND BACK
- Cramp in muscles of neck, 8, 12.
- Pressive sense of fatigue in the cervical muscles, close to the occiput, especially on the right side, 5. [640.]
- Does not like anything to touch him; inclination to unbutton the collar of his shirt, 10.
- On turning the neck, over the left scapula, and also on taking hold of anything, painful aching, which comes suddenly, and then becomes continuous; twenty-four hours later, over the right scapula, 4.
- A fine stitch between the shoulder-blades (after two hours), 1.
- Pain in the back, as from fatigue, several days, especially after eating and while sitting, 3.
- Short sticking-tearing pain, especially in the lower right side of the back, near the right hip, 5.
- A pain in the small of the back, before and on rising from the bed, as if one had carried a weight there; after rising, it disappears.
- Rheumatic pain in the lower part of the back, just above the sacrum, mornings, 5.
- Sharp stitches in the region of the kidneys on moving the arm, 2.
- Pain in the loins, 10.
EXTREMITIES IN GENERAL
- Insensibility and coldness of limbs; weak, almost imperceptible pulse , without vomiting (child), 32. [650.]
- Right arm and hand and both great toes were cold to the touch, 16.
- Heaviness in all the limbs (eighth day), 8.
- Great heaviness in the feet and arms, so that she must let them sink down, 4.
- Constant inclination to stretch the limbs, 10.
- Weakness of the limbs, 50.
- Weakness in all limbs (sixth and seventh days), 8.*
- Weakness of limbs, especially legs, 13.
- Extremities tired and weak (second day), 8.
- Fatigue in the limbs, 5.
- Burning and tearing in the joints (sixth to seventh day), 8. [660.]
- Drawing and tearing in the joints (eleventh day), 8.
- Slight rheumatic drawings through the whole right hand, immediately afterward, drawing through both legs from above downward, especially in the region of the knee, and noticed on walking (two hours), 5.
- (Tearing in the limbs), 2.
- Tearing and drawing in joints, 11, 13.
- Tearing and drawing in the extremities (eighth day), 8.
- Rheumatic and bruised sensation in the limbs, on rising and shortly before it, 5.
UPPER EXTREMITIES
- Frequent twitching of the tendons in the arms and hands, 19.
- A kind of dislocated pain in the right shoulder, 4.
- A cracking in the shoulder-joint, with tearing pains to the hands, 2.
- Soreness in shoulder-blades, 15. [670.]
- Short, rheumatic pain, around and in the shoulder-joint, and the left breast, 5.
- A violent tearing, externally in the right shoulder, followed by itching (after one hour), 1.
- Violent itching in the left shoulder; after scratching, a number of small vesicles arise, and she must scratch till they bleed, without relief to be itching whereupon the spot burns; the vesicles dry after three days, 1.
- Fine stitching and twinging below the left axilla; then a stitch, with twinging, on the condyles of the left elbow (after two hours), 1.
- A twinging sensation in front of the left axilla, as if one raised the skin (after two hours), 1.
- Tearing twitching in the arm and left side, 2.
- Severe jerking in the right arm, is not relieved by motion (immediately), 3.
- Burning on the inner surface of the right upper arm, toward the shoulder, with yawning (after two hours), 1.
- A drawing down along the outer surface of the left upper arm, almost as if in the bone, in several short paroxysms, 4.
- A fine boring in the right humerus, as if in the marrow, which frequently increases, then extending into the shoulder, frequently somewhat diminished; it disappears on pressure, and is relieved on motion of the arm, but frequently returns (after one hour), 1. [680.]
- Short, rheumatic pain in the left elbow, 5.
- Itching on the external surface of the right elbow, which disappears on scratching (after three-quarters of an hour), 1.
- On the forearm near the wrist, an eruption of pimples like the itch, also on the upper arm; the itching is relieved by scratching, 2.
- Transient, rather severe tearing in the muscles of the left forearm, 5.
- A twinging or sensation as if something would raise the skin, on the inner surface of the left forearm; on pressure it disappears, but returns again (after half an hour), 1.
- Violent itching on the external surface of the left forearm; on scratching, small pimples appear, which burn, and the skin becomes rose-red, but white on pressure; the redness continues two hours (6 P.M.), .
LOWER EXTREMITIES
- Numbness and coldness in the legs, 16.
- Lower extremities heavy and stiff, as if lamed, 12.
- Drawing, tensive pain in lower extremities (fourth day), 8.
- Tension and tearings in lower extremities, 12.
- Rheumatic pain in and over the left hip, 5.
- Just below the left hip, transient rheumatic pains, 5.
- Spasmodic twitchings of the muscles of the thigh (eleventh day), 8.
- Tension in the hamstrings on walking, evening, 2.*
- Rheumatic drawing in the upper part of the right thigh, 5. [710.]
- Twinging on the anterior surface of the left thigh, as if one pinched him, or raised his skin with a needle; the spot continued to pain still longer in the open air (after two hours), 1.
- Fatigue in the knees, 7.
- Burning pricking in the knees, 4.
- In the morning in bed, and on rising, aching in the bones of the knee-joint, as if the limb had no power, and as if the tendons were overstretched and strained, 2.
- Tearing, a hand's breadth above and below the knee, on the external surface (after two hours), 1.
- Evenings in bed, sticking in the knee and hip (first day), 3.
- On the left side below the left knee, a slow, throbbing, sensitive picking, in rest and motion, 4.
- Painful cramps in the calves, 31.
- Cramp in the calves frequently wake him, 16.
- Cramp in the calves, afternoons, disappears on walking about (fifth day), 3. [720.]
- Spasmodic drawing sensation in the calves (ninth day), 8.
- Soreness in calves, 15.
- Tearing internally in the right calf, and at the same time burning externally (after half an hour), 1.
- Slight twitches in the left calf (second day), 3.
- Rheumatic pain on the left side of the left calf, 5.
- Tearing and itching on the external surface of the left calf (after two hours), 1.
- Violent pinching and clutching in the left calf, and from the popliteal space to the external malleolus; extremely painful, .
GENERALITIES
- Face and whole body very pale (twelfth hour), 19.
- Loss of seven pounds, in weight, in three weeks, 11.
- Spasmodic movements, 24.
- Convulsions (death in a few hours), 19.
- Convulsions and loss of consciousness, 29.
- Convulsions and tetanic spasms, 53.
- She lay on the ground distorted by cramps, rigid, as if dead; one foot was gangrenous and afflicted with most violent pain, 21.
- Constant contraction of all the muscles, especially of the abdomen and upper extremities (two hours), 52. [750.]
- Vomiting and epileptic spasms (inunction on a child), 38.
- As soon as he got warm in bed, at night, he sprang into the air, 2.
- *Trembling, 19.
- Whole body trembled and felt very sick, 12.
- A very peculiar internal trembling (third day), 3.
- Long-continued trembling of the head, and a paralytic trembling in the hands on every motion (15 grains), 19.*
- Throbbing and pulsating in all the vessels of the body , perceptible externally, yet without anxiety, only with ill-humor, 2.
- Relaxed condition of the whole body, 3.
- His condition was such, that he might have been taken for a man intoxicated on wine, 47.
- Blood loses fibrin, and becomes thinner, 12. [760.]
- Restlessness excessive (ninth day), 8.*
- Either general restlessness or nausea, 18.*
- Restlessness, vertigo, syncope, 50.
- Anxious restlessness and tossing about (fifth day), 8.
- Great general discomfort, which starts from the abdomen; he groans and moans involuntarily; restlessness drives him from sitting to standing, and walking about, .
ANTIMON. ET POTASS. TART. SKIN
- Rash, where the salve had been rubbed in, 25.
- Reddish rash, 2.
- Rash on the arms, breast, and occiput, 2.
- Itching eruption on the skin, 39.
- Eruption of bright red, small, conical, distinct, hard pimples, with an inflamed base like lichen simplex , thickly covered the breast, anterior surfaces of the upper arms, wrists, hypogastrium, and inner surfaces of the thighs, 16. [800.]
- Vesicular eruption over the body (internal use), 42.
- A very itching rash, which suppurates, 20.
- Rash over the face and whole body, with profuse sweat; respiration very difficult with continued heat, thirst, and headache, 20.
- Painful pustular eruption, 18.
- Pustules, when it is rubbed in, also on other parts of body, as nasal fossæ, margin of anus, glans penis, genitals, arms, etc., 39.
- A thick eruption like pocks, often pustular, as large as a pea, filled with pus, 27.
- Eruption of itching pustules, which soon dry up, 12.
- From applying antimonial ointment to the dorsal region considerable local eruption was produced; in six days itching on scrotum; on ninth day five pustules on scrotum and three on penis, 39.
- Eruption of pimples and vesicles, which in two days are filled with pus, are like the pustules of small-pox and are very painful; these pustules dry up and form crusts; this eruption appears first on the internal surface of the forearm, then on the back (from internal use), 40.
- At first small, red pustules; the third day increased in number and size; the fourth day most of them had a brown everted margin, were covered by crusts similar to cow-pox, and contained much matter in the centre; the sixth and seventh days some were as large as the thumb-nail, shaped like a flat ulcer, and contained much thin matter, 20. [810.]
- Most of the suppurating places became confluent the eighth day, and discharged blood and matter, 20.
- The corners of the nostrils are ulcerated and painful (four hours), 2.
- Cracked lips, at night, on waking (fourth day), .
SLEEP AND DREAMS
- Yawning, 50.
- Frequent yawning, 14.
- Frequent, great yawning, 4.
- Frequent yawning, although she has slept sufficiently, 1. [860.]
- Yawning and stretching the limbs, 4.
- Constant stretching and yawnings, forenoons, 3.
- Inclination to sleep, 11.
- Inclined to rest and sleep, 12.
- Inclined to sleep, with anxious dreams, 12.
- Great desire to sleep, 33.
- *Great sleepiness (ninth day), 8.
- Exceptional sleepiness and overweening inclination to sleep, 18.
- Forenoons, great desire to sleep; if he sits still he sleeps immediately, with vivid dreams of a continuation of his previous thoughts (second day), 3.
- The eyes close involuntarily, forenoons; he falls asleep, and often starts up violently, but at once goes off again (first day), 3. [870.]
- In the morning, at 10 o'clock, could not get out of bed from sleepiness, and was so heavy and inclined to sleep, and his limbs were so tired and gone-to-sleep that he could hardly stand, 28.
- At 10 A.M., he still feels a disposition to sleep, which he is unable to shake off; he is so fatigued and prostrated that he can scarcely keep himself up, 42.
- Sleepiness by day, 2.
- Such an irresistible inclination to sleep by day that when he went about and stood, fell asleep as soon as he sat down, 2.
- Even when getting on horseback, in the strong air, he feels sleepy, and can hardly overcome his drowsiness, 42.
- Could hardly keep awake, and was dizzy when riding in the open air, 28.
- Evenings (quite contrary to custom), he is sleepy very early that he can hardly keep awake, and half an hour later he becomes wide awake and remains so till late at night, 4.
- Unusual sleepiness at night, 28.
- Great drowsiness and inactivity, for two days, .
FEVER
- Cold skin, 44.
- Cold sensation on skin, 11.
- Chills, 11, 14.
- Chilliness, 3.
- He is chilly and very cold, 2.
- Violent shivers through whole body, 17.
- Slight chilliness (third day), 8.
- Feeling as if cold run through all the vessels (soon after taking it), 4. [920.]
- Feverish chills, 13.
- Constant chilliness with very warm clothing (sixth and seventh days), 8.
- Chilliness from within outward, spreads from the spine over the abdomen and extremities (fourth day), 8.
- Chill at night and on rising in the morning, 2.
- Severe chill several forenoons, 3.
- From morning till evening constantly chilly, as soon as she goes from the room into the open air, 1.
- During normal stool cold shivers through the skin, 12.
- Chill over whole body, with trembling and shaking at 3 P.M. (for several hours), 2.
- He looks pale and suffering, and is so chilly on going into the open air that he trembles, 4.
- Chilliness, as if cold water had been dashed over him, with gooseflesh on the arms, and repeated yawning (soon after taking it), 4. [930.]
- In the morning after rising, for half an hour, chill, with gooseflesh, and likewise at 7 P.M., for two hours, after which thirst follows, at 9 o'clock (third day), 1.
- Chilliness, with gooseflesh and cold skin over the whole body, which remained a long time on the hands (ninth day), 8.
- Trembling and chilliness over whole body, always from within outward, without ability to get warm, with a general sick feeling (eighth day), 8.*
- Slight chill, drowsiness, and weakness, 14.
- Warmth of skin, 11.
- Temperature elevated, 12.
- Unusual heat of the body, 18.
- Violent heat, .
CONDITIONS
- Aggravation.
- ( Morning ), Head confused; on waking, head heavy, etc.; heat on forehead; heaviness in head, etc.; twitching-tearing in right ear; violent toothache tongue thick yellow; after rising, mouth sore, etc.; after waking, sour taste in mouth; on waking, sour taste at back of tongue; dryness in throat, etc.; loss of appetite; frequent eructations, etc.; early, colic around umbilicus; after rising, cutting in rectum, with stool; cough, etc.; pain in lower part of back; in bed and on rising, aching in knee-joint; on rising, chill; after rising, chill, etc.; on waking, profuse, general sweat.
- ( Forenoon ), Head heavy, etc.; sticking in urethra; frequent urination; stretching and yawning; eyes close involuntarily, etc.; severe chill.
- ( Afternoon ), Headache, etc.; coating on tongue thicker; on motion, surging toward neck upwards, etc.; on sitting crawling in abdomen; cramp in calves; constant heat.
- ( Toward evening ), Hopeless, etc., etc.; fretfulness, etc.; catarrhal symptoms; sore feeling in chest, etc.
- ( Evening ), Pain in side of forehead, etc.; heaviness in head, etc.; burning in eyes; on lying down, twitching-tearing in right concha; ulcerative pain in right concha; itching heat in upper lip; on going to sleep, whirling in pit of stomach, etc.; late, aching in pit of stomach; toward 9 o'clock, cutting in abdomen; two soft stools; frequent urinating; voice changed; in bed, suffocative feeling; on waking, tension in hamstrings; in bed, sticking in knee, etc.; on lying in bed, itching in the sore; in bed, itching biting in left sole; heat all over.
- ( Night ), On waking, bad headache etc.; on waking, cracked lips; violent nausea and vomiting; stomach feels loathed, etc.; whirling, etc., of the heart; chill screams, etc.; chill.
- ( Before midnight ), Cough; sleeplessness.
- ( Midnight ), Wakes with thirst, etc.
- ( Morning till evening ), Constantly chilly.
- ( Morning till 5 P.M .), Headache, etc.
- ( 11 A.M. till evening ), Stitches in head.
- ( 2 P.M. till 3 A.M .), Sticking in forehead.
- ( 2 to 3 A.M .), Cough, with expectoration.
- ( About 3 A.M .), Suffocated.
1 P.M .), Headache etc.; cramp, etc., in bowels; pain above pubis, etc.
- (
3 P.M. ). Head heavy, etc.; nose-bleed; chills all over, etc.
- (
4 P.M .), Feeling of heat in head.
- ( Toward 6 P.M .), Tension in abdomen.
- (
6 P.M .), Febrile chill.
- (
7 P.M .), Chill, etc.
- ( Towards 8 P.M .), Fever.
- ( Open air ), Twitching on left thigh; from warm room, constantly chilly; chilly.
- ( Motion in open air ), Tearing in left temple.
- ( Walking in open air ), Canine hunger; head, etc., feel swollen.
- ( Anger ), Cough.
- ( Bending head forward ), Pain in upper chest.
- ( Sitting bent ), Pressure in abdominal; pressure in abdomen, etc.
- ( Deep breathing ), Pain in right side.
- ( Closing eyes ), Vertigo.
- ( Coughing ), Heat, etc., of forehead; dull pain in forehead; vomiting of food; heat, etc., of hands, etc.
- ( After dinner ), Qualmishness in stomach; sensation as if overloaded in stomach, etc.; tearings in rectum; sleep.
- ( Drawing in the abdomen ), Sticking from below pit of stomach; small spot in abdomen hurts.
- ( After drinking ), nausea.
- ( After eating ), Nausea; nausea and vomiting; rumbling in abdomen; pain in abdomen; cough; pain in the back; violent heat, etc.
- ( Expiration ), Stitch in abdomen aches.
- ( Before each epileptic attack ), Burning in chest.
- ( Taking hold of anything ), Aching in neck.
- ( Trying to lift head from pillow ), Dizziness.
- ( Looking at object a long time ), Sight vanishes.
- ( After a meal ), Creeping, etc., in abdomen.
- ( Motion ), Heat in head; stitches in head; pressure in forehead; trembling of hands; chill, etc.
- ( Rapid and violent motion ), Pain.
- ( Moving arm ), Stitches in region of kidneys.
- ( Pressure ), Pain in pimples on upper arm; burning in left breast; stitching in fingers; pimples on buttock pain.
SUPPLEMENT: ANTIMON. ET POTASS. TART. Authorities.
55 , Dr. Mackintosh, Lancet, 1827-8 (2), 536, A. B. took 20 grains in a little sugar; 56 , Usher Parsons, Bost. Med. and Surg. Journ., vol. iii, 1830, three servants took over 40 grains each; 57 , Wm. F. Porter, M.D., Lancet, 1832 (1), p. 46, effects of a large quantity; 58 , George Lefevre, M.D., ibid., 1844 (1), p. 444, a lady swallowed 25 grains; 59 , J. T. Gleaves, M.D., West. Journ. of Med. and Surg., 1848, R. æt. twenty-four years, took a tablespoonful; 60 , John S. Beale, Lancet, 1854 (1), p. 68, a girl, æt. sixteen years, swallowed from 40 to 60 grains, death; 61 , C. Ellis, M.D., Bost. Med. and Surg. Journ., vol. lv., p. 400, fatal poisoning of Miss ---, æt. twenty-one years; 62 , John Gabb, Med. Times and Gaz., 1866 (2), p. 379, a man, æt. forty-three years, took 3 teaspoonfuls; 63 , Alfred Nobiling, Versuche uber die Wirkungen des Brechweinsteines in kleiner Dose bei längerena Fortgebrauche, München, 1868; 64 , Sharp's Essays on Medicine, 1874, p. 725, took Ant. tart. 1st, 1 drachm; 65 , John Morley, Brit. Med. Journ., 1876, p. 492, a lady, æt. eighteen years, took over a teaspoonful; 66 , F. Mason, ibid., 1877 (1), p. 674, a man swallowed 80 grains.
- Pustular eruptions of the tongue and lining membrane of the mouth, of the character of those produced on the skin by the application of the ointment, 57.
- Pulse 72 (before experiment); 70 (after two minutes); 72 (after five minutes); 67 (after ten minutes); 72 (after fifteen minutes); 71 (after twenty minutes); 74 (after twenty-five minutes); 68 (after thirty minutes); quickened by the deep breathing, 70 (after thirty-five minutes); 72 (after forty minutes); 77 (after fifty minutes); 66 (after one, and two hours), 64.
- Breathings 18 (before experiment); 20 (after four minutes); 18 (after eight minutes); 14 (after twelve minutes); 13 (after eighteen minutes); 12 (after twenty-four minutes); 10 (after twenty-eight minutes); deep uncomfortable sighings, 8 (after thirty-four minutes); 7 (after thirty-eight minutes); 6 (after forty-two minutes); 12 (after fifty-two minutes); 18, natural (after one hour), 64.
- Rolling upon the ground in great agony, vomiting blood, and tormented by agonizing colic pains, 58.
- In half an hour violent nausea was induced, but vomiting did not commence till 2 P.M. (after three hours), after which it became more violent till three, when it seemed at its height; a quantity of bile was at first ejected, afterwards painful strong retching, with an obtuse fixed pain at the epigastrium, which was not always referred to the same spot, and accompanied by great thirst; a slight discharge of mucus at intervals ensued. About 4 P.M., the above-mentioned symptoms gradually disappeared, and were succeeded by great and universal prostration; two very copious, bilious stools were passed. In the evening, after taking some tea, a profuse perspiration broke out, which appeared to be the last effect of the medicine, 55.
- Unable to stand; scarcely able to speak; exhausting evacuations, both from the stomach and bowels; weak, contracted pulse; cold clammy sweat; extreme paleness; prostration of strength, 56.
- In about two hours he felt an inclination to evacuate his bowels, and the alvine discharges continued involuntarily. Breathing slow and laborious; face pale and altered, features shrunken; eyes fixed and turned upward, pupils dilated; surface cold; appeared to be unconscious, but stated afterwards that he knew what was passing around him; the action of the heart was intermitting and extremely feeble, and no pulse could be felt at the wrist (in three hours); complained of great thirst, and a sense of burning in fauces, œsophagus, stomach, and lower bowels (in seven hours); throat sore; fauces covered with pustules, some of which, having discharged their matter, have left soft superficial ulcers (second day), 59. [980.]
- Within a quarter of an hour after vomiting came on, very sharp; and a little while after smart purging. These symptoms continued for about three hours. She also complained of pain down the œsophagus, and described it as "burning her." She then fell asleep. The vomited matter was very dark. Delirious during the six or-eight hours previous to her death, .
SUPPLEMENT: ANTIMON. ET POTASS. TART. Authority.
67 , Dr. Molin, Des Spécifiques en Médecine, Paris, 1847 (Brit. Journ., vol. vi, 1858, p. 118).
Observation 1.
- Being in a good state of health, my pulse beating 64 per minute, I took at 8 A.m., before breakfast, 5 milligrams of Tartar emetic in water. This dose was repeated for five days without perceptible effect. The sixth day I felt nothing until 4 P.M. The respiration then appeared to me a little less free. Feeling no further effects, and my appetite continuing good, I took on going to bed about 9 o'clock, a dose of 1 centigram. The night was passed in a restless manner, and the sleep interrupted by a fatiguing heat; I felt necessitated to drink several times; the respiration was slightly impeded; on rising, general uneasiness, weariness, similar to what follows a febrile fit, the mouth clammy. I took at 8 o'clock in the morning, 1 centigram. No appetite; a simple soup for breakfast without relish. All the day I was in the same state. About 5 P.M., greater uneasiness, especially about the epigastric region; nausea; desire to vomit, but without result; respiration more impeded; short dry cough, pretty frequent; great thirst; heat in the head; white tongue; drinks appear always too sweet; clammy mouth; two loose evacuations during the day; palpitation of the heart; bruised feeling and general weariness, compelling me to go to bed at 8 o'clock. The ear applied to the chest gave evidence of nothing abnormal, except that the respiration appeared much too rough. At 9 o'clock I took another dose of 5 milligrams. Agitated sleep, difficult respiration, feeling of pressure on the chest during sleep. At 5 A.M., I was awakened by a violent rigor, it lasted twenty minutes, and was followed by heat; the pulse, which had been little affected during the two previous days, increased to 78, was full and strong; skin hot; face red; thirst urgent; heat in the head; pretty strong palpitation of the heart; slight burning at the stomach; fulness and inclination to vomit; respiration very much impeded; feeling of pressure and constriction of the chest; cough frequent, and a little moister; on auscultation, the respiration appeared rougher than the previous evening, and deep inspiration was accompanied by slight pain under the left nipple. Night very agitated; nightmare; disagreeable dreams. I felt much the same in the morning as I had the previous day, but deemed it advisable not to carry the experiment further. During the subsequent days, the following symptoms occurred. The tenth day no stool; towards evening, pulse 72; respiration somewhat less difficult; cough the same; hardly any pain in the side; great thirst; a good deal of uneasiness; no inclination to vomit; night, a little less restless. The eleventh day, a little less roughness of respiration on auscultation; cessation of the pain; pulse nearly normal; skin still hot; thirst less; uneasiness diminished; appetite in part returned; respiration still obstructed; cough a little less; the night more tranquil. Twelfth day, appetite; breathing nearly free; the cough continues; still a little uneasiness; scarcely any thirst; tranquil night. The symptoms continued to diminish the subsequent days, so that by the eighteenth there remained no trace of indisposition, except slight cough, which persisted some time longer. Not being sufficiently edified by this single experiment, three months subsequently, I commenced another.
Observation 2.
- During eight days, I took each morning, 5 milligrams of Tartar emetic, without feeling anything. The ninth day, at 8 P.M., I took another dose of 1 centigram; night somewhat disturbed; the respiration appeared somewhat less free, but that was not very distinct. The tenth day, on rising, a little weariness; I again took 1 centigram. During the day I had some uneasiness; mouth clammy; little appetite; breathing impeded. About 10 P.M., I took another close of 5 milligrams; sleep very disturbed, and towards morning uneasiness, especially at the epigastrium; some nausea; loss of appetite; respiration impeded; a watery stool at night; great fatigue; urgent thirst. From the morning of the eighth day the cough appeared, and went on increasing; it is short, frequent, and painful; auscultation gave no results. At 9 A.M., 1 centigram was taken. In the course of the day, rigor, which lasted half an hour, with burning in the head and beating of the heart; thirst; inclination to vomit; pulse 80, strong; skin hot; cough dry and painful; considerable difficulty of respiration; sensation of weight on the chest; auscultation shows rough respiratory sounds; general bruised feeling. This state continued all day and night, which was very much disturbed by strange and fatiguing dreams. There were two watery stools during the twenty-four hours. The following days the symptoms declined, but more slowly than the first time, so that by the twenty-fifth day I had not entirely recovered my health, 67.