Asa foetida

Volume I — Main text

ASAFCETIDA.

Fifula Asafoitida^ L. Nat. Ord,, UmbMjlerjt, The gum-resin^ obtained by incision from the living root, is the part employed.

rl* Froviagf, — 1. Franz. [This is a pathogenesis consisting of symptoms from Hahnemann, Gross, Gutmann, Stapf, and Franz himself. Their contributions, however, are not distinguished, and no information is given as to how the drug was taken. — Eds.]

Immediately, tensive shooting in r. upper arm, from above out at inner side. Aher J h*, weakness in head. Superficial twitching on inner side of 1. thigh. After I h., pressure in r. side of face from within outwards. Pressivc shooting pain in r, lower ribs, extending to flank of that side. Attacks of slight pinching in hypogastrium. Drawing preasive pain with tightness of chest. Slight twitching in r, big toe. After J h., obtuse pressure in sternum 5 going ofl' on in- and tx-piration, but returning while writing. After i h., pressure externally in forehead. In region of eyebrow cramp-Hkc drawing across. Pinching in bowels with discharge of flatus.

■ Obtuse shooting m L shoulder. Twitching in 1, shoulder. Boring pressure on inner side of 1. forearm, from within outwards* Pressive pain under r. calf, goen ott on walking. After ij h., pressure in r, temple. After ij h., painless rumbling in bowels. Arter ij h., pressivc pain in r, side of forehead, from within outwards. After a h», sharp shooting near penis In pubes. Fine burning stitches in and behind r. scapula, towards ribs. Pressure in r. side of nape. Fine tensive stitches in r, shoulder.joint towards inside. Quivering in deltoid. Pressure on outer side of 1. forearm. Twitching of muscles of I. thigh. Sharp outward shooting in r. tibia. Quivering in 1, sole towards toes. After ij h., burning shooting in l. eye. After t J h., pressure in forehead with exhaustion of whole body. Pressure in L ear. Fine sharp stitches in navel. Violent sdtch in hypogastrium. Diarrhoea with bellyache, Pressivc pain in r. scapula. After 3 h., whirling in head. Tensive drawing in I. upper ^ arm on its inside. Violent tearing pressive pain in whole r. leg, less when walking.

^m After 3 J h., sharp stitches externally in 1. side of belly, removed by rubbing. After H 4 h., crawling pricking in umbilical region. Quivering in deltoid. Twitching in ^m muscles on outer side of 1. upper arm. Burning shooting in r. patella. Sharp shooting ^ nms down 1. tibia on inner side. Sharp shooting on dorsum of r. foot, goes otf on walking. After 44 h., pricking burning in I, cheek. Drawing shooting pain in L aide of chest. Weak movements in 1. intercostal muscles. After 5 h., pressive pain in forehead, from within outwards. Itching in skin of abdomen below navel. Itching pricking in skin in r. side of hypogastrium. Flatus with diarrhoea. Pressive stitches in r. thoracic cavity, followed by pricks, with pressive pain in ribs near spine. Pressure in I. intercostal muscles from within outwards, aggravated by inspiring and expiring. Fine stitch from r. loin to ribs. Quivering in muscles of r. thigh. After si h., burning in 1, eyeball as from within outwards. After 6 h., pressivc pain in forehead. Pinching in bowels. Stitch in r. ribs. Tiresome backache, especially

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under ^capul^. Backache in r. side. Itching |>ncking in 1. ttbia in front below the knee ; goes off on walking. After 7 h,, burning in r. elbow-joint, on it* outer side. After 8 h., press! ve shooting in back of r, hand. Pressure on roots of middle and index fingers of r. hand. After 9 h., quivering in 1. shoulder -joint towards outer side. Pressure on inner side ot thumb* After 9^ h., pressure on 1. side of occiput. After 1 1 h., rumbling in bowels. After 1 1 h., burning in r. eyeball. Drynefs in ocsophigu* ; when swallowing, tensioa there. Shooting pinching in 1. side of belly. After 11 h., pressive pain out at navel. After 23 h., Quivering shooting in 1. side of belly, when in- and ex-ptring. Cutting pinching in bowels. Twitching in r. ccrvicaj muscles. After X4 h.» pressure in L cheek. Stitches in region of diaphragm, r* side. Obtuse stitcher externally in 1. scapula. Tensive stitch in dorsal muscles of L side, from below upwards. Fine stitcnes in r, 3rd toe, when walking. After 15 h., quivering in r. thigh anteriorly. After %6 h«» tensive burning in r. eyeball, pressive pain in r. side of chesty from within outwards. Tensive shooting in 1. loin continuing during in* and ex-piration, going off when walking. Fine pricks like needles about L loin. Stitcher in 1. shoulder-joint, from within outwards. Shooting pain on inside of I. upper arm. Fine stitch on elbow. After 27 h., pinching sharp stitches on r. inner side of ribs. Itching of skin on patella. After 29 h., burning pricking in navel. Pain in back, especially in r. scapula, Pressive pain from r, wrist to r, index* Obtuse stitches in r. glutafi muscles. Quivering in inner side of r. knee-joint. Obtuse shooting in 1. ankle-joiut on inner side. After ^o h., pressive pain in r. side of head* Can work no longer on account of backache. Itching in r. knee-joint on tts inner side. Unusual desire to sleep. Out of humour and disinclined to v%'ork. After 3 1 h., pressure in nose as though it would burst, especially in r. ala. After 32 h^ pneviiTe shooting in sternum from within outwards. After 34 h., pressive pain in middle of sternum with a kind of nausea up from chest. Twitching sensation in internal mus* cle» of 1. upper arm. After 36 h., coryza. Quivering in l. knce-joint on its inner side. On 1. tibia pressure^ goii^g off on moving. Quivering in r, ankle-joint inferiorly. After 37 h., pressive pain in L intercostal muscles from within outwards. After 41 h,, boring shooting in 1. loin from within outwards^ going off on in- and ex-piration. After 42 h., itching in r, scapula. Quivering in muscles of 1. scapula. Itching pricking under r, inner ankle, goes off on rubbing. Digging in inner side oi 1. foot. After 43 h,, boring shooting on inner surface of r. upper arm, not going off by movement After 45 h., pressure in 1. side of head from within outwards. Digging pressive shooting in L loin from w Ithin outwards to ribs, with anxiety. Obtuse stitch from thumb towards back of hand. After 46 h., pressive pain in r, sole when sittings After 47 h., boring obtuse stitches in L side of ribs outwards, when inspiring and expiring. After 48 h., quivering in 1. shoulder-joint towards inside. Burning stitcli on outer side of r. upper arm. Twitching drawing in 1. thigh. Pressive pain tn dorsum of 1. foot when sitting. After 49 h,, itching in r. eye. Pressive pain in r. ear. Transient stitches in r. side of back. Quivering of anterior muscles of thigh in upper halt. Itching creeping on under surtace at r. big toe. Burning pressure at root of 1. big toe. After 54 h., cutting pain under r. scapula. After 5? n., tensive stitches in I, pectoral muscles. After 60 h,, needle pricks externally in penis. After 61 h , burning drawing in r. intercostal muscles. Fine stitch in 1. knee when sitting. After 62 h.| burning in L eyebrow. Burning stitches in r. eyeball. Obtuse stitches outwards in 1. side of abdomen, with flatulence. After 63 h,, along with constriction of throat pressure in chest. Obtuse stitches in L ribs. Sharp shooting burning in tip of 1. index. After 64 h,, shooting in thoracic cavity extending to fauces^ when standing and sitting. Pressive beating in thoracic cavity extending to tauces wheil^ standing and sitting. Fine stitch in elbow. Fine long stitch in bend of elbow. After 66 h. itching in dorsum of foot. After 67 h., digging shooting outwards from diaphragm to , hypochondrium when inspiring and expiring. After 68 h., pressurt in I. temple from within outwards. Pressive shooting in r. upper arm on its inner] surface from within outwards. Quivering in r. glutei muscles. Burning pricking til I little toe. After 69 h., pressure in thoracic cavity out towards r. side. After 70 h., shooting in 1. side of belly from within outwards. After 72 h., itching in r. cheek. Tensive burning in 1. calf, isr d., rush of blood to head with heat of f^ccij Headache as if muddled in head, during which attention is apt to be overstraioedU Confusion of head with pressure in temples. In forenoon obtuseness of senses, especiail]f; of hearing j be hears nothing distinctly, has always to ask twice. Great feeling of

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diyness of mouth, though he has moisture enough in it. Drawing down along 1. side of neck when moving. Loathing at beer, it tastes fWtny. Perceptible pulsation In pit of stomach. Soon after eating pressure in gastric region. Violent pres^sivc p;iin m pit of stomach towards hepatic region^ when sitting. Sudden violent jerky stitch from r. side of abdomen outwards, from within to external integuments. Stitches in 1. side of belly when walking. ' Contracting pain under navel when standing. When walking after dmner, twisting pain in abdomen. Drinking disagrees with liim, causes immediately weight and cooling sensation in bowels. In iliac region, on drawing in abdominal muscles, a pre&sive pain. On bending chest forwards pressure on lower art of sternum. Drawing pressive pain along 4th and 5th last dorsal, and 1st iumbar vertebrae, as if along their bodies. Pressivc ^acraJ pain, especially when bending the body back and forward* Stitches along sacral bone, down to anus. Pain in perinxum, as i( something blunt pressed out there. 5titchei> in latksimus dorst near upper arm. At outer end of clavicle, when sitting, a pressive pain. Drawing pain about head of humerus^ when he held arm still, with a kind of trembling over, excitement (34 after a great debauch) in its muscles which he must alnrays keep moving. Tearing pains up along forearm, on moving fingers. Tearing in 1 femur when sitting. Drawing pressive pain in tendons of hough on stretching them. Great weariness when moving ; as long as he lies or sits still he feels strong, except a feeling of faintness when his mouth becomes dry. In afternoon, flushing of heat on cheeks. — and d., sensation in brain under upper part of frontal bone, like undulation and quivering, m. Near frontal protuberance externally, continued burning pricking, with pain like ulceration, relieved by touching, but immediately returning. Pressure in both eyes. Bellyache in upper abdomen as if chilled, and as if diarrhoea would come on, with a kind of bulimy. In m.^ feeling in gastric region and whole abdomen, as if all were bruised there, with feeling of fulness in stomach and eructations. Pulsation in pit of stomach, perceptible to finger. After eating, pressure in gastric region, with great faintncs*. On merely compressing abdomen, pressure in lower part of stomach (xiphoid cartilage) with nausea and feeling of fubaess in pit of stomach. Shooting outwards in both sides of belly after eating when sitting, going off by pressing on it. Across abdomen^ pinching drawing when sitting, with obtuse stitches going outwards in I. side of belly. In 1. side of hypogastrium violent shooting and drawing that extends along inside of o& ilii, when sitting, m. After eating, tension in abdomen, as if he had over-reached himself. Semation of grvat discomfort in whole abdomen, with great weight in it and pressure in its sides, m. Crossness and anxiety, which seem to come from abdomen, when he has a little difficulty in fixing his attention, m. Soon after dinner, when lying, great oppression of chest with pressure and throbbin|^ in it. Stitches and pressure on chest when lying, with very dimcult, sobbing, jerky mspiration, going off on pressing on chc^t with the hand, and when sitting up. Drawing along 1. side of neck down* wards on moving. Paralytic drawing pain along 1. shoulder and down upper arm, when at rest* Tearing stitches upwards, followed by burning. In r, forearm when at rest. In the wrist bones, pain a* if beaten. Pressive drawing in bones of wrist and instep on moving. When lying and at rest, drawing pressure on backs of fingers, and blows from forearm to elbow,

Nq itme givtn, — ^Dizzy. Stupefying tension in head, especially 1. side. Brain feeU very expanded. Slight headache in forehead. Drawing, undulating pressure through I. half of forehead, ending in a numb pressure on frontal protuberance. Under r, frontal protuberance a slow intermitting pain, like beating outwards. Feeling of tensive confusion and oppressive weight of forehead (after olfaction). Fine needle pricks in L frontal protuberance. Under r. frontal protuberance single quick and deep stitches, like blows, and sensitiveness remains there afterwards Feeling of pressure on crown. In r. parietal bone, pain as from a peg pressed in deep. On 1. side of head a pressure coming on suddenly, quickly increasing, as from a blunt instrument pressed in ; goes off suddenly. A couple of fine superficial pricks on r. side of top of head. In r. side of head, above ear, a drawing, that changes into a simple fhooring. In 1, temple, intermitting inward -pressure almost like beating inwards. Above r. temple, a sudden transient obtuse pressure. In 1. temple, suddenly, a pain like a sharp peg pressed in. Single deep stitches in 1. temple. Slow succes&ive obtuse stitches in 1. temple. On outer border of 1. orbit, dull pre&sure. In upper eyelid, frequently a quivering movement. A transient numb

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pressure on middle of 1. upper ryelid* For i d., penodical burning is cyci^m comptession of eyelids as if ^Icep would come. Tirtsomc dryness and dry frelifl^W eyes. A kind ot dimne^ of eyes; when writings the letters are dimmer «» if a Uighfl veil were over them ; goes off after vomiting. On various parts of fmcc, /^. im xvgoma, nasal bones, painless tension, i^ith a kind of numb feeling. Slight mmsicQii drawing on outer border of r. concha. Repeated short drawing in both external mcitijy auditorii. Clear ringing in ear. On rami of lower jaw^ sometimes a tran9iciiE^|fl like prolonged cramp. On 1. angle of chin» in a small space, a numb pft|^^| extending to the tootn exactly opposite. Nausea. Intermitting pinching t& jBB abdomen. Visible pukations in pit of stomach. Burning in aodomen. Pt9|H perineum as if something blunt pressed out there. Increased discharge of ilaiiM Pinching in belly with discharge of flatus. Slight, sometimes almost quite inM 'oluntar) discharge of flatus, which he hardly notices. More frequent -^r ' ' ti usual. For 3 d., two to three loose stools daily with bellyache. For 4 hur , ]

three to four diarrhofic stools with bellyache. Violent sneezing several tiinsr? mu,,u^ d. In trachea, so choky that he must frequently cough, and the cough is hoAr»4 After dinner, stitches in region of last true rib on r, side, and oppression of 1 hevtJ Below r. axilla anteriorly, a pressing inwards, increasing in Hts, without oppreMnom of breathing. Boring ^ititches m I. thoracic cavity from within outwards, €qu|^fl felt when in- and ex-piring, and continued « Below I. axilla^ some Rne suped^H but acute, needle-pricks. Below I, axilla, a transient inward pressure. In 1. sc^fl^| repeated transient drawing. Burning in dorsal vertebrae^ more towards i. tide (M back. Quivering in muscles of lower halt of back when sitting. Nredte*pricki iu all intercostal muscles, when sitting. In the region of short ribs, round about over the back, a jerking constriction. Tearing sacral pain when sitting. In 1. upped amii near shoulder-joint, intermitting cramp^like pres$»ure. In tlow intermiisions, on inside of L forearm, cramp-like drawing radiating upwards. Obtuse shooting otm inner side of r. forearm. Cramp-like twitching in r. tbrcarm downwards, v i r j 1

as if hand would get numb. Scraping sensation on ulnar %ide of wrist. A 1

becomes occasionally stronger on outer side of 1, wrist, at side of thumb. Un mrta-j carpal bone of 1. middle finger a kind of numb pain, as if a heavy body lay upon itJ In the flesh between metacarpal bones of 1. thumb and index, tramp4ike patii.l Cramp-tike painful twitching in metacarpal bone of L thumb. In r. palm adult paisij as from a body pressing on it, with sensation as if hand would become numb. On r«| thumb a transient cramp-like pain, not interfering with its movements; soon atierJ wards in L thumb. On moving fingers, tearing pains up along forvanm. Burning odl anterior surface of thigh when sitting. Pains in flesh of r. thigh, as if a &har}i bod^ were sticking in it. On outer surface of L thigh, on a small spot just below hip-joint;^ dull but painful pulsating stitches. Tensive drawing in r. thigh on its inncf udcM On outer side of thigh paralytic drawing pain when sitting. A restlessness (trcmbiingji in thigh and leg when sitting, like the violent pulsation of the arteries after al pedestrian journey. On inner surface of 1. thigh superiorly, painful twitching iJ slow fits. On anterior surface of 1. thigh near knce^ repeated undulating twitcbingJ Prcssive pain behind 1. patella. Stitches in knee near patella when sitting, the tattrll pains when touched as if sore and ulcerated. In upper part of knee, on a small spot burning pain, which sometimes changes into burnmg pecking. Quivering on out^ side of 1. knee joint. General twitching in muscles at upper part of r. tibia« In I leg (when one is crossed over other and hangs down) feeling as if it would bccoine numb. Ltg'i easily go to sleep where their nerves are ever so slight], Uf^^

when he crosses his leg while sitting the other leg goes to sleep inm Qq

r, instep, tension as from a tight boot in irregular nts. On inner ^luc ui j. foe painful intermitring beating. In ball of 1. sole, feeling as if had stood long on itj In 1. big tot occasionally a painful pecking. In 1. big toe a simple sometimes pcckiuj pain, when at rest or when moving. Painful pecking in tip of big toe. Ncrdlf pricks, fine superficial, but paintul pricks as with pins here and there, must rub On several parts of limbs transient cramp-like drawing, like twitchine. Feeling a heaviness of whole body. Feeling of general exhaustion, the limbs fall down hcavilj and limply, and head is dizzy. Sleep full of dreams of things formerly done, 1 spoken of. Gay dreams of company and feasting. After dinner, febrile state, with hot feeling in face, no thirst, but anxiety and drowsiness. Very irritable and mg indifferent to everything. (ArcAia^^ i.)

1. LEMBK.E. 1 6th March, 1868, 3 p.m.y 5 grs. in water. 4 p.m., pressure and heaviness in forehead. Frequent pressure in shoulders, most in r., in knees, most in r., when sitting. Wandering shooting pains in knees and ankle-joints when sitting, sometimes changing into feeling of pressure. Heat in cheeks and forehead, witn weight, 5 p.m. Frequent collection of saliva in mouth, teeth on edge. Shooting in joints of some fingers. Drawing and pressure in occiput. Drawing pain in r. cervical muscles. Pressure in muscles of r. upper arm. During the continued heat in face and forehead, chills in back and cold hands, 5.30 p.m. Drawing here and there in muscles of r. thigh. Constant eructation of air with garlic taste. Drawing in muscles of 1. scapula. Severe pressure in joint of 1. thumb and later in joints of other fingers. When sitting frequent slight palpitation of heart, more like a trembling of heart. Shooting in r. calf and like pinchmg, lasting long. Then the same pain in muscles above r. knee. Pressure in sternum ; also when walking pressure in ankle-joints and knees. The other pains repeated and alternating all e. The heat of face continues till 7 p.m., and ears very hot externally. Frequent drawing in forehead, 7 p.m. Especially severe pressive pain in r. ankle-joint when walking, lasting long and recurring ; and in 1. ankle-joint the same pain occurs later, also when sitting, but worse when walking. Severe boring above 1. ejrebrow, 7.30 p.m., then the same r. Towards 8 p.m. the symptoms gradually go oft. — 17th, 6.30 a.m., pressure in knees and muscles of r. upper arm. 8 a.m., 6 grs. Pressure in knees and wrist-joints. Pressive pain in 1. thumb-joint. The urine passed smells distinctly of asafoetida. Pressive pain in muscles of inner side of r. thigh, in r. ankle-joint, repeatedly, also attacking 1. ankle-joint, both when sitting and walking. Drawing pam in r. toes. Heat in tace, 8.30 a.m. Frequent eructation of air with taste of asafoetida. Pressive pains in shoulder-joints. Drawing pain in occiput. Pressive pains in knees and ankle-joints when walking. Pressive drawing pains under 1. border of ribs when walking, and in muscles of scapulae. Pains in knees particularly acute and long. lasting, and very often in joint or 1. thumb, 9 a.m. Tearing pains frequently in forehead. Pressure in 1. side of thorax, in elbow -joints, under 1. scapula, in hands, shoulders, Sec, Severe shooting in r. calf when sitting and walking. Cutting in abdomen when walking and sitting, i p.m. Whilst walking and sitting the pains in knees, anklejoints, and muscles of thighs. Same pains in joints of upper extremities and below 1. border of ribs, also in 1. scapula. Frequent tearing in forehead and occiput. Repeated shooting in urethra also observed yesterday e. During e. the pains came in limbs, forehead, and occiput. At 9 p.m. all pains gone, n. good. — x8th, 6.30 a.m., 7 grs. Soon heat in cheeks. Pressive pain in r. knee, ankle-joint, and elbow. Pressure on top of head and r. side of forehead over eye. Drawing pains in occiput and shoulders. Drawing in skin of whole outer surface of 1. leg several times, 7 a.m. and later. Drawing in fingers, muscles of scapulz, thighs, and r. cheek. Above pains in joints return. Drawing in calves. Frequetit eructation of air with taste of drug, 8.30 a.m. Drawing in several finger-joints, back of wrist, and feet. Moving af^cted joints aggravates pain. These symptoms repeatedly. Tearing in r. temple. Shooting drawing pains in r. knee and above it, worse when walking. Much shooting in jerks, especially in joints of 1. little finger, aggravated by movement. All d. when walking several of above pains. Pains less in e. At 6 p.m. severe pressure in wristjoints and temples. Drawing in occiput, later in r. ankle-joint, repeatedly. At 8 p.m. severe drawing in lower incisors. Pressure in shoulders, dorsum of foot, and in joints formerly affected, but less severe. — 19th, 6 a.m., after rising, pressure in forehead, drawing in muscles of r. forearm and muscles of 1. cheek. Pressure on r. tibia and 1. calf. Drawing and pressure on different parts of forehead. 7.30' a m., 6 grs. Drawing in scapular muscles, toes, hands, nape, occiput, repeatedly. Pressure in knees and above them, in bones of toot when sitting, and in forehead. Great heat in cheeks 8 a.m., felt also externally ; great heat in ears, which bum and are red, muscse volitantes. Severe drawing on 1. tibia. Pressure in and on r. side of sternum, in bones above forehead. Along with heat in face, cold hands and feet with chilliness in back, 8.30 a.m., continues till 9 a.m. Continued drawing in muscles of r. thigh, it then goes into knee and down to ankle-joint, where it causes pressure which extends into the knee, when sitting. The pains in lower extremities also when walking. Repetition of former symptoms. At 2 p.m., 7 grs. Besides above symptoms, pressure and drawing in bones of head, knees, and toes. At 1.30 p.m. neat in face, sinciput, ears, also externally in said parts. Shooting and itching in eyelids. The other

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palfts in joints, ihor%x, and dorsal muscles incrcas«. Pressure tn joint o4 u and above r. wrist on its back. Shooting in skin of r. foreaxtn, 4 p.m, Alo continued heat of face and cars, and with warm hancU^ cbillmess in K Soon after hands become ice.cold^ the cold in back increases and continu pulse, continued pressivc pains in joints of toes, hands, feet, and knee?., cr l.: i, n tips of toes, in skin of r. axilla, on r. cheek. At 5 p.m, the cold in back begin* to leteen and hands become warmer. Later the former sj^mptoras recur. At ig in bed, repeated severe pressure in r. wrist-joint and then in r. temple. — ^:iotl| same pains and pressure in nape at 6 a.m, in bed, immediately after wakini rising pressure in 1. knee, then in r. tibia, then in 1. ankle-joint when walk stooping severe shooting below I. scapula* Shooting in toes^ pressure in mu scapulsE and in shoulder-joints^ increased by moving, 7 ajn. Drawing in s«etYraI| of hones of head, in feet, forearms, alternately here and there, in wrist -joints qu ct jumping from one place to another, in dorsum of feet, incalvcs^in temples. Si in skin on outer surface of L thigh. Numb pressure in temples and $h" Drawing in nape muscles* 7.30 a«m., 7 ?rs. Drawing pains in all finger.jotnts^ Soa heat in tace, burning in cheeks and ears, heat in nape and occiput, and constant obtsix pressure in region of lumbar vertebnct and wandering pains in joints. Shooting A skin of forehead, of r, thigh, drawing In calves. Much eructation of air with taste of drug* Drawing and shooting round about L ear, repeatedly. 8 a.m., musr tantes. Drawing in r. side of lower jaw, 8,30 a.m., then tn r. side of fo Drawing behind 1, ear. Shooting in skin of 1. cheek, then of r. Pressure l border of ribs anteriorly. At 9 a in. hands begin to grow cold and there is ch in back, the pain& coutinue uninterruptedly, now here, now there, with heat 01 i.. -. and face. Severe pressure in some dorsal vertcbrx, 9 a.m. Some bruised pain jn elbows and shoulder-joints. 3 p.m., 7 grs. The former symptoms repeated. Sometimes slight shoots in urethra. 3.30 p.m., heat in head, face, and ears, with external heat of these parts, muscae 'oli tantes. Pressure in forehead, drawing in L tide of lower jaw, in shoulders, fingers, toes, and their joints. Shooting and itching ia borders of eyelidsj 4 p.m. Drawing in muscles of legs. Shooting in tip of tongue and pressure in joint of lower jaw. Along with outward heat and pressure in head there occurred, about 5 p.m., a transient attack of confusion when sitting and reading, followed by recurrence of heat in head, but soon afterwards there was chilltnest ia back, whikt face, head, ears and hands were still hot, especially the heat in eyes and cheeks, with itching, pricking, and burning in eyelids, especially r. Then the coldness in back increased, went to arms and legs, hand«» became cold, a shivering through whole body, nails blue, much saliva in mouth, and occasional eructation witn taste of drug. 5.30 P.m., uncomfortable feeling in pit of stomach like pressure, not exactly pain fnl, crawling in skin of back, pressure and drawing in the above p3 " ^ limbs and head. The coldness lasted till 6 p.m., but the hands got warm. < ness and heat went off by 6,30 p m. Towards e. all the symptoms diminished. — i*>u» 7.30 a.m., 10 grs. The pains came on more severely, especially those in knees, shoulders, and bonc?i of head. At 8 a.m. heat and burning in checks, with increase of former pains. At 8.30 a.m. coldness of hands with blue nails, with continuance of heat of face and head^ visible twitching of r. lower eyelid, shooting in tip of toiiiuc. pressure 00 sternum, chilliness in back, wandering pains. Pressute in I. ank! for a long time while walking. 3 p.m., took 2 teaspoonfulsof an emulsion madi I drachm of asafort. (quantity of cxcipient in cmuUion not stated, hence dose of asaf. not given). Soon heat, not only m head but feeling of heat along back, and increase of the well-known pains, especially in feet, forehead, wrist-jomis, knees; boring in r. inner canthus, pains worse when sitting than when walking. Drawing and shooting in calves, muf^cles of arms here and there, most in flexors. Pressure and weight in head. 4 p.m., 3 teaspoonfuls. Taste loathsome and scraping in mouthcannot be got rid of. Constant flow of saliva. Chilliness in back, cold hand drawing in muscles above knee. Pressure in thumb-joints. Feeling of hung longing for something strengthening and refreshing. Stronger and weaker flusfae heat in face, with cold hands, severe drawing and pressure here and theie in rnus of r. thigh, weight and pressure in sinciput and forehead, cheeks and ears extremei hot, witli chilliness in back, shooting in tongue. Pressure under 1. border of no anteriorly. Hands alternately warm. Pressure here and there in thoracic walls aQ dorsal muscles. Some biu\sed y^vvl vn \imw^t% uV >x^^ct -arttk^^wi vbv ^«m&c[oint9

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ankle-joints, and very severe in some parts and some attacks. Frequent eructation of air with taste of drug and great flov%' of saliva* Drawing in finger-joints. Several times alternation of chilliness in back and cold hands with heat, whereby the head is always heavy and with pressive pain in it ; slight movement in warm room causes immediately severe chilliness, 5 p.m. On walking up and down room several times there occur chilliness in back, cold feet, cold hands and blue nails. When walking about pressure in r. ankle-joint and up to calf. Smarting burning pain in tip of tongue several times, repeated later. Prewive pains, sometimes very severe, on both sides of spine in neighbourhood of short ribs, sometimes aggravated by moving body, repeated later. Urine darker than usual, Freouent burning in r. eyelids, drawing pains in joints of lower extremities, frequently. The fever went off at 530 p.m., and there remained only a feeling of heat, 6 p.m., y tcaspoonfuls. Same symptoms as before. 9 p.m., 3 teaspoonfuls. Between 6 and 9 p.m., appetite not affected. In fiict, during the proving hitherto there has been no disturbance of digestion or stool. After this o p.m. dose the same symptoms ; among the others visible twitching in upper eyclicf, burning in skin on outside of I. leg, the pains under border of 1, ribs. — 22nd, 6.30 a.m,, some pain In knees, wrists^ fingers, shoulders, pressure in forehead, or on 1. side of back near short ribs. 7 a.m., 1 teai^poonfuls, which produced the diarrhoea of asaf. The well-known pains come on and leap from one part to another, heat in head and cheeks. 7.15 a.m., stronger pressure in occiput and forehead, on muscles of forearm^ in wrists, in L angle of lower jaw. No alteration in »tools. 8.15 a-m,, coldness as before with the pains in ankles, knees, elbows. Pressing asunder in both temples several times, often very severe. Drawing in toes. Severe wandering pains in occiput. The coldness lasts till 9 a.m, 1 1 a.m., nausea and hunger at same time, Tnc former symptoms occur all d., are ameliorated in c., and arc gone at n, — 13rd, m., immediately after rising pains in knees^ ankles, muscles of extremities — ^thesenot felt in bed. 7 a.m., 10 grs. asaf.dep. Soon the well-known pains increase. At 7.30 heat in head^ face, and ears, muscae volitantcs. Increase of pain!i in finger.joints and nape muscles, 8 a.m., 12 grs, Verv' great heat of face and head along with the former pain, especially severe pressure m some dorsal vertebrae. Burning in border of r, eyelid, pressure on zygoma and in muscles of legs, burning in tip of tongue, 8,45, chilliness in back, cool hands, severe pressive pains in knees when walking, 9 a.m., 16 grn. For long time shooting and burning in end of urethra, but not when urinating. Whilst walking same pains as before, 1.30 p jn., ao grs. 3 p.m., also 20 grs. Increase ot heat and paini^, especially in back about 1. short ribs and in joints of legs. Severe pressure in knees and ankle-joints, when fitting. Pressure in frontal bone on different parts, sometimes along with shooting and burning pain. Bruised pain in lower limbs when sitting, especially in knees. Pressure in some toc-joints, in shoulder and clbow.joints. Shooting in tips of toes, pressure and drawing in calves. Severe pressure in small spots of skull, 5 p.m. Repetition of the same symptoms, especially drawing in r, tibia. 9 p,m., pains much abated, none at n. — i^th, 5.30 a.m., after waking in bed tearing in r. snoutder and several times in 1. tibia, after rising in I, ankle.joint, toes and finger-joints, Drawing in 1. calf and I, chest. When stooping some pain behind near L short ribs. Several times severe pressure in 1, shoulder, wrist -joints, muscles of legs. Drawing and pressure in muscles and joints of arms. — a 5th. On rising the pressive drawing pains in joints of limbs, in skull, calves, muscles of arms, fingers, wrists return, weaker than yesterday ; they occur both when moving and when at rest, more so in latter case. Drawing and pressure In facial bones, sometimes very violent. — 26th, Some, but very slight symptoms. — ^3 7th, 7 a.m., 5^- ^^ ^ ' i ^ ^^^ heal in head, face, back, and the well-known pains in limbs recommence, 7.30, another Jss. Among other symptoms especially i«vere pressure and asunder- pressing in temples, continued. Constant pressure behind near I. short ribs, 8.30 a.m. About 9 a.m. there began chilliness in back, coldness of hand* with constant heat of head and face, shivering through limbs. Pressure in frontal bone for several h,, and in maxillary joint. Heaviness in forehead and sinciput lasts all d, 3 p.m., 5^, and 3.30 p.m. another 5ss. Former symptoms repeated. In n. and next m. on rising some pains in joints and skull. — a8th, 7 a.m,, 5S *nd the same at 7,15 a.m. Repetition of former symptoms. — 29th, Several symptoms, but rarer and weaker, especially drawing and pressure in knees, ankle-joints, skull bones, muscles of limbs, wrists, tibiae. On 30th all symptoms gone. (iSr, Z,/ Hem. Kim.^ xiii, 119.)

1. GoNT7>on March jtst, 1814, took i gr. in piU-fonn at 9 a.m. On A\ml rtH^ at 9 a.m., took 5 grs., followed at 5 p.m. by pressing pain in cardiac region, as if from ovcr-fiUing and distension of heart, lasting, with bncfintcrvals, 4 h, and accompanied by smaller pulse ; at 8 p.m. 1 loose stool. On April 9th, a(ter 6 grs*. felt occasional rumbling in bowels. Same result followed a 10 gr, dose. On April i7th» at 9 a.n^j took 15 grs. Towards c. and next d. in forenoon had slight nausea, a* if from flfl empty stomach, with distaste for food. By midday both symptom* had disappcard" {J oKC, op. r/V.)

2. Lip PERT on March agth^ 1824, at 9 a.m,, took i gr. Towards 10 a.m. con^ fusion of head came on, changing^ gradually into heavy pain as if whole brain ^cH pressed together ; this was accompanied by giddiness, warmth of skin, and arcel-nt^ circulation. These lasted till towards 4 p.m. At 5 pm. ire<iucnt ft '|| eructations set in, ceasing only next m. at 9 a.ra,, alter abundant, soft, br u-I smelling evacuation. On March 30th, at 9 a.m., took 1 gn. At 10 a.m. felt prrvvflg ^nsation at epigastrium, at 5 p,m. slight transient giddiness. No stool pa«Acd thi 4, Next m. was seized with confusion of head, increasing gradually to actual pain, which kept coming and going periodically until late at n. On April ist, ait ex mucU straining, passed a copious hard stool. Repeated same dose on and with same rt%ut|d except that stool next m. was inclined to be loose. On this d. too (3rd) in c. c^^^lfl siderable headache came on. Sleep was not disturbed, but on 4th pain ^vas still tbeit and lasted all d. with varying intensltyj but never ceasing entirely. After dose* of 4 and 6 grs., experienced only belching and confusion of head. After latter <io<^ bowels acted several times during d., but were not actually relaxed ; much flatus wa also evacuated. Similar results followed dose of 8 grs., except that bowels remain^M con6ned until next m., when a scmi-relaxed stool was pas?fed. Aitcr to grs. taXdfl April 10th, at 9 a.m., head remained quite dear; usual belching* occurred during afternoon, and next d. two diarrhoeic stools were passed. Same effects followed do*e of I a grs. (Ibid.)

3. Otto took i grs, on March 19th, 1814, at 9 a.m. After J h., pressing pains in occiput came on, spreading gradually over whole head, and causing sensation **of brain being surrounded and pressed together by a cloth. Whilst this s}'mproflll increased^ thorax was seized with spasmodic contraction, in consequence of which Q seemed as if lungs could not expand completely, although respiration was meanwhile normal. These symptoms disappeared gradually after i^ n., first head and then chest becoming quite free. 20th, 9 a.m., took % grs. After J h., constrictive pain in head came on, but less than yesterdays on other hand, constriction of chest was increased so that pulse was small, contracted, and irregular, beating only 60 insteai| of 65 per m. After a h., symptoms began to pass off; pulse, however, was neaiM

4 h. in resuming ordinary rate. During d., before and during micturition, drawing in glans penis was felt several times, a 2nd, 9 a.m., took 4 gi5. After 4 h,» uM pleasant taste, soon passing on to nausea, set in. At 10 a.m. came on grnil^

Ijicssing and drawing pain in region of cardia, spreading first towards spleen and ater towajds liver, and aggravated by pressing diaphragm downwards, preceded by considerable rumbling in intestines and a few eructations, and accompanied also by previous contraction of chest and acceleration of respiration, although to a moderate extent ; pulse meanwhile being more rapid and smaller than usual. These symptoms disappeared during afternoon, but evacuations later on were soft and yellowish, containing less bile than usual, but without any odour of drug. 13 rd, 9 a.m., took

5 grs. with same results, only that bowels did not act till next d*, when motion %ms firm, dark brown, and smelt not unlike drug. In chest only slight drawing w^ respiration being only slightly accelerated, and pulse smaller, quicker, and contracted than usual. Head during afternoon was confuted and seized with prcsMH pains, as if a cord were tied tightly round brain. Towards c,, drawing in gj« penis came on ^ urine was dark brown, easily passed, and deposited no woimcnt, bu nad rather strong and pungent smell. a4th, 8.30 a.m., took 6 giv. Rumbbng ill intestines, and increased warmth and pressing in gastric region soon followed i Ta%t» mentioned this time to greater extent, spreading less to 1. side and not at all to r., but ascending more upwards into oesophagus, and causing sensation as of foreign body rising. These symptoms ceased at noon, but abdomen remained distended, although neither wind nor faeces passed this d. Contraction of chest lasted irom 1 o till 11, and was accompanied by quickened pulse and respiration, former being small

ASAFCETIDA. 4^7

and contracrted. During afternoon drawing in glans penis was more evident than from previous do^ew, and kept coming and gomg although micturition wa« nnalfected, except that urine had strong pungent odour. At 8 p.m,, was suddenly seized with giddiness and dimness of vision. Shortly afterwards cold sweat broke out on forehead and extremities, with cutting pains in abdomen so severe as to oblige him to go to bed ; here symptoms moderated, but lasted fully an h. Stool next m, was firm, dark brown, and smelt of drug. Took 8 gre. on a6th, at 9 a,m. After aj h., nauseous taste in mouth came on» which soon changed to that of onions, lasting nearly whole d., pulse and beat of heart being meanwhile small, cjuick, and irregular. Chest lymptoms were slighter than usual. Towards midday, rumbling in intestines came on, becoming gradually more marked, and changing during early afternoon to pressing in stomach. At same time spasmodic constriction ot chest, coupled with dry irritating cough, caused by tickling in windpipe, was felt. When former bad lasted 4 h», O — felt slight ri^or reaching from last dorsal to md lumbar vertebra, but not beyond this point. After rigor ceased, pressure in stomach came on, changing later to stretching pain, and spreading to r. and 1., and increased by pressing diaphragm downwards, or if gastric region was touched externally. Pulse as in torcnoon was small and quick. When these thoracic and abdominal symptoms had lasted nearly 3 h,, general malaise came on gradually. Constriction of chest increased to anguish^ respiration became impeded, causing general restlessness, which compelled him to go hither and thither. Head meanwhile fck muddled, and thinking difficult. Felt also mentally restless, and unable to keep to one subject. From time to time rigors spread over whole body, but without subsequent heat* These symptoms were much relieved by an hour's walk in open air, but had not disappeared at jo p.m. Abdomen remained distended during afternoon and e., because neither faeces nor wind were evacuated. On other hand, during e. was troubled with feeling as of substance rising from stomach through oesophagus into pharynx, causing him to swallow frequently ; this relieved him, but only temporarily. Urine was lighter than from previous doses, but smelt as before. Next m,, on awaking^ noticed head muddled, very slight constriction of thorax, with somewhat quicker cardiac and arterial pulse, gentle

Sressure in gastric region, becoming worse after a little time, and fulness and intension of abdomen. Bowels acted before 7 a.m., motion being small and yellowish brown, consistent at first and then pappy and soft, smelling not unlike drug. These symptoms gradually disappeared, muddled condition of head lasting longest (till e.), From this dose appetite was decidedly diminished. After 9 grs., early symptoms were much as before. Shortly after i p.m., chest became so constricted that it appeared as if same were s<^ueezed by heavy body lying on sternum. Respiration and pulse were affected as before, with occasional coughing and yawning. Coupled with these thoracic symptoms felt congestion towards head, face became hot, and head began to ache. Feeling came on in eyes as of grains of sand between eyeball and lids, and as if cool wind were blowing upon eyes from without, pupils meanwhile being unusually dilated ; at same time peculiar drawing developed in articulations of lower Jaw, changing to moderate pain j this soon abated, but was repeated once during e. Other symptom* were same as from last experiment, but milder. After quiet n,, awoke with slight pressing headache and distension of abdomen ; both vanished after bowels acted at 7 a.m. After dose of 10 grs., all these symptoms were repeated with addition of scraping feeling in oesophagus. At 4 p.m., abdomen became unusually distended. Bo%vels acted shortly afterwards, excreta being hard, dark brown, and foul smelling, and gave pain at anus in passings after awhile this relieved distension of abdomen ; latter was distended from time to time, but was relieved by passage of 6atus* All symptoms gradually decreased until towards 8 p.m., when all reappeared; headache spread this time from 1, frontal region over whole head, and pains in jaws spread to muscles of neck. Condition reached it"* worst at 1 1 pm., then moderating rapidl^^, so that by 11 nearly all symptoms had ceased. After restless n., felt some contusion and pres.ing pain in head on awaking, with considerable distension of abdomen and very moderate feeling of constriction of chest Soon after rising had dark brown, soft, yeasty, and foul-smelling stool. All symptoms had vanished by midday. Repetition of dose was followed by same symptoms. Next m. remarked constriction of chest, quickened respiration and pulse, and distension of abdomen. At 9 a.m., pressure in stomach came on again, and distension of abdomen became very troublesome. During m., felt drawing and tearing pains in neq

extending from occiput down neck to arms, resembling rheuroadc pains. Urine liid pungent and ammoniacal odour, (Ibid.)

1. PiENiTZ took I gr, on March i8th, 1815, at 9 a,m. Next d., at 8 ajn., was seized with sharp colicky pains in abdomen, with rumbling 111 intestines, distension ol abdomen and loss of appetite, followed by three watery stools. Coupled with these J were heaviness and confusion of head, with pressing pain spreading over whole head,! Puiie was small and les* frequent, skin cold and dry. By midday these symptoii»J had entirely ceased. After 2 gn>., noticed no ill-effects until next d., when he haiH four watery evacuations, without pain^ but with much passage of flatus dowuM^riM in spire of which abdomen remained distended during whole d. Pulse was meaix^^H small and frequent. After 3 gt^,, felt nothing till next d,^ when two soft evacu^^^| and much flatus passed, without pain in alxlominal organs. Had, however, feeli^^H heaviness and fulness in abdomen lasting till midday. Pulse was small, weak/lHI somewhat frequent. On April i5th> at 9 a.m., took + grs. At ji a.m.* felfl trembling over whole body, skin being cold, and pulse small and weak. At midday 1 had no appetite. In afternoon felt two transient stitches, one after another, in head, commencing in forehead and extending to occiput, leaving conftision of head, lasting under J h., and accompanied by slight acceleration of pulse. Next m, had iwtfl liquid stools, followed by rumbling in intestines, heaviness and distension of same^l lifting till midday. Next d. had three liquid stools with acute pressing pain to^vmrdffl rectum. After 6 grs., bowels acted twice towards c., evacuations being yeasty • samJ thing occurred on following d. During same d. that this dose was taken^ genitiiM remained tor several hours in excited condition. {Ibid.) I

2. SiEBENHAAtt took I gr. on March a6th, at 9 a.m. This was followed bvl rumbling and gurgling in abdomen. Aft:er a gt^., noticed same symptoms. witiiJ confusion of head and full and quick pulse, lasting till towards c. Same rtsuh&l followed 3 gns., with addition of actual pain, especially in region of stomach. A 111 symptoms only lasted till tow^ards e. Dose of 4 grs. was followed -i !/ byfl following effects ; Heaviness and conftision of head \ peculiar pressing f '^t^«J relieved after mucous expectoration ; bellyache with active movements ;iiig nimblingl in intestines; some loss of appetite at midday ; persistent inclination to go tu stdot, j followed either by hard farces or nathing at all ; full and quick pulse ; and genenil J malaise. These symptoms lasted nearly whole d. to same extent. After 5 grs,> felti same effects, but more intensely. On rising next m., felt very marked nausea amll great inclination to vomit ; latter remained undiminished after brcakfa<it (of bread I and butter) and he felt quite out of sorts generally. Both symptoms lasted till mid J day, and instead of appetite for dinner he felt considerable urging to vomit. N<» vomiting occurred, bur frequent belching of foul-tasting flatus, At j pjn,, nauscJ abated, and condition improved generally. After walking for x h, \n open air during! afternoon perceived a peculiar affection of genitals, in consequence of which letticle J became pamful, especially to touch or on movement, lasting 4 h. (Ibid,} I

3. JoRG, on March 3ist| at 9 am., took i gr. After J h. cutting in umbilicill region came on. increased on sitting down and pressing abdomen^ and lasting till e. S coupled with this i'th peculiar movements in stomach and in oral cavit)", spasmodtcl conti^ctlons of former alternating with increasing nausea and inclination to vomit,! appearing frequently a^ if peristaltic movements of intestines were inclinetl to bccomJ reversed, and as if this inclination had been already communicated to gullet i nal vomiting followed, but, after much urging to stool, passed four evacuations of hard! or pappy faeces. Abdomen remained distended all rest of d. in spite of frequenci passage of flatus. Next m. woke with same inclination to go to stool, but bowels did! not open all d. After ij grs. felt again cutting in umbilical region, lasting as before, ■ and along with this several transient stitches in and under frontal bone, and later pressing and burning under sternum with frequenr irritation and cough. Taste was after I h, better, became after 1 h. foul and acrid, with slight nausea. After 1 h, J distension of intestinal canal came on, with same apparent reversal of peristaltic I action, lasting with occasional intermissions till late in e.j former being worse in after- ] noon and e., apparently from fact that after constant attempts to evacuate bowel only 1 small, dry, hard f^ccs were passed. Next d. had repeated cutting in umbilical region j with distension of abdomen, and persistent constipation in spite of constant urgiog J to stool ; pains like spasms at stomach, and a feeling kept coming and going a^ u I

urns were raw- Constipaiion las»ted all next d. On Aptitjth^at 9 a.m., tooJL a Ma«.J

Very shortly felt severe cutting pains in abdomen, burning in region of stomach and diaphragm, distension of abdomen and freouent urging to stool, very littk hard or soft forces being passed. Simultaneously felt confusion of head with frequent stitches in frontal and temporal regions, lasting till nearly midday. During fore* and afternoon had same feeling ot rcvcrstcd peristaltic movement of bowels^ and feeling of urging in gullet from stomach towards mouth. During afternoon rheumatic pains icame on In upper and lower extremities. In region of scapula, but more ei^peciafly in 'jomts, situation changing at tlmes^ lasting till e. During e. noticed rancid tatty taAtc in mouth. Next d. noticed same symptoms as from previous doses, with irritable condition of gullet and taste In mouth as if he had eaten and drunk too much the d, before, Appetite during d, was lessened, and in e. felt very tired and sleepy.

1. Frau Ch., after i gr,, felt slight cutting In umbilical region, with mild pressing headache, especially in forehead. After i^ gr^, besides above symptoms had troublesome dryness in gullet without thirst and constant urging to stool although consti* pated. After 1 gn^ early symptoms were same as before. Later on had waterbrash several times and occasional cutting pains in abdomen. Next d. felt nearly all d. pressure in stomach, pressing pain in forehead, and dryness in gulteL Had constant but fruitless urging to stool. July aSth, 8 a.m., took a J grs. After 5 m. felt burning in g^illet^ after J h. burning in stomach. After ij h. felt pressing headache^ especially in r. half; and after a h. acute labour-llke pain in region of uterus, lasting 5 m., and recurring twice within i h. During afternoon and e. felt great lassitude and weariness with desire for sleep. Burning in throat and stomach lasted all next d., changing into dryness, without thirst, lasting till 3rd d. Bowels remained constipated. Took 3 grs. at 8 a.m. Felt immediately burning in gullet and stomach. After 1 h. felt pressing headache, especially in forehead, with small and quickened pulse (10 beats per m. above normal). This state of pulse moderated towards midday, and cca-scd towards 3 p.m. After 4 p.m. had several attacks of above- mentioned uterine pains. Burning and pressing in stomach lasted till next d., when they were replaced by dryness in gullet and sensitive pressing pain in stomach; this alternation continued tilt 4th d., experi* meiiter meanwhile complaining each d. of great lassitude towards e. Bowels remained constipated. After 14 h. catamenia appeared^ 10 d. before usual time j flow was very scanty for 3 d., later became natural. {Ibid.)

2. L— took 1^ grs. on July 18th, at 9 a.m. Felt pressure at stomach lasting whole d. with heaviness and confusion of head, changing towards e. to troublesome weariness. Heaviness of head frequently amounted to veritable pressure over eyes, as if from great sleepiness. Same symptoms followed dose of 3 grs., pressure at stomach appearing also next d., lasting all forenoon.

1 1. Th,, after 3 grs. taken at 8 a.m., felt pressing headache, especially in forehead, burning in throat, pressure in stomach, and heaviness in whole body, all symptoms except last vanishing before 4 p,m, {Ibid,)

la. Eduaud JoRG took %\ grs. on July 28th, at 8 a.m. After ^ h, felt pressing and cutting pains in stomach and abdomen, lasting till midday \ contusion of head proceeding from 1. half of vertex, changing to pressure towards eyes lasting with varymg intensity till midday. After 3 gth. felt same pressure at stomach lasting 3 h., and simultaneously confusion of head, changing at noon to vertigo. (Ibid)

13, Theodor JtiRG, on July a8th, at 9 a.m., took %i grs. After i h. felt ansient stabbing in I. thorax ; after 2 h. pressing headache, especially in forehead and vtr eyes, together with dryness in mouth. After 3 grs., felt after j h. pressure at Stomach j after 1 h. premising headache descending towawls eyes and nose, fasting 4 h. Pressure in stomach was associated with much gnimblirtg and rumbling in abdomen, passing off late in the e. with abundant passage of flatus downwards, (ibid.)

II. Poisonings. — ^i. "In the very frequent employment I have made of asafcctlda as a plaster on the abdomen, I have seen in men undoubted swelling of testicles, and in women inflammation and great swelling of genitals; a short time ago this happened to such a great degree in a woman at Bergen that I had to treat her antiphlogistically. Although the woman was 50 years old, and the catamenia had long ceased, her breasts swelled as much and secreted a milky fluid as though she w-as In the 9th month of pregnancy," (Boas, Casper's med, Wochmsch.^ No. 51, p. 83a. 1841.)

a. Jahn reports nymphomania as occurring in a full>blooded woman after taking strong d osics of asaf. {mat* Med. , i , 4s 3 . )