NO16 , obtained from Solanums, especially from S. nigrum and S. dulcamara.

Preparation , Triturations.

Authorities.

Reil's Journ. f. Pharmacodynam., 1857.

1 , Dr. Clarus, took 1/2 grain of the acetate first day, 1 grain second day, 6 1/2 grains third day; 2 , Schroff, Lehrbuch f. Pharm., 4th ed., p. 623, proving of Solanin from S. dulcamara on four persons; 3 , Froumüller, Klin. Studien, etc., gave to several persons doses of 1 to 4 grains of S. from S. tuberosum and nigrum, no symptoms; afterwards took 6 grains; 3 a , same, persons took 15 grains.

MIND

Stupefaction without previous excitement, 2.

HEAD

Vertigo, 2, 3a.
Head hot, heavy, dull painful, 2.
Heaviness of the head, 1.
Pain in the occiput, 1.

EYE

The pupils were not much affected, perhaps somewhat contracted, 1.

MOUTH

Salivation, 2.
The pure alkaloid has a cooling, acid, and salt taste, and when chewed, it causes a glutinous sensation in the pharynx and throat, with scraping, which extends down to the stomach, where it becomes a peculiar sticking pain, 2.
Bitter taste, 3.

THROAT. [10.]

Scraping in the throat, 1, 2, 3a.

STOMACH

Constant eructations, 2.
Nausea and diarrhœa, 3a.
Nausea, and violent ineffectual efforts to vomit, 2.
Nausea and vomiting, 3.
About 5 P.M., vomiting three times without previous nausea, without pain and without any intestinal symptoms, 1.

ABDOMEN

Rumbling in the abdomen, 2.

URINARY ORGANS

(The next morning, examination of the urine showed albumen!), 1.

RESPIRATORY ORGANS

Hoarseness, 2.
Respiration slightly slower than natural, temperature not affected, 3a. [20.]
Very superficial slow respiration, 15 or 16 to 14 to the minute, 1.
Difficult respiration, with oppression of the chest, 2.
Oppressed respiration, 1.

PULSE

Pulse increased in rapidity, weak (72 to 88), 1.
Increased frequency of the pulse, sometimes as much as 25 beats, lasting four hours (the next morning, somewhat slower than natural), 2.
The pulse ran up to 95 and 100, was remarkably soft, small, and weak, 1.
Pulse rose from 76 to 92 in fifteen minutes; in twenty minutes more it returned to the normal, 3a.
It caused after ten hours slight slowness of the pulse and respiration, but no change in the temperature, 3.
Pulse small, weak, thready, 2.

INFERIOR EXTREMITIES

Slight tonic spasms of the lower extremities, 2. [30.]
The next morning the prover felt quite well, with the exception of some weakness in the lower extremities, 1.

GENERALITIES

Weakness, 1.
Sensation of great weakness, 2.
Sensitiveness to light, noise, and to touch, 1.

SKIN

Skin dry, 2.
Hyperæsthesia of the skin; creeping along the spine when touching the skin; more easily tickled than natural, 2.
Itching of the skin, 2.

SLEEP

Frequent yawning, 2.
Great sleepiness, with inability to sleep, 2.
Sleepiness, 2. [40.]
Sleep very restless, frequently disturbed by frightful dreams, 2.
Sleep frequently interrupted during the night, but without dreams, 1.

FEVER

Extremities cold, 2.
Profuse perspiration without weakness, 1.

Solaninum