SOLANINUM.

NO16 , obtained from Solanums, especially from S. nigrum and S. dulcamara.

Preparation , Triturations.

Authorities.

Reil's Journ. f. Pharmacodynam., 1857.

1 , Dr. Clarus, took 1/2 grain of the acetate first day, 1 grain second day, 6 1/2 grains third day; 2 , Schroff, Lehrbuch f. Pharm., 4th ed., p. 623, proving of Solanin from S. dulcamara on four persons; 3 , Froumüller, Klin. Studien, etc., gave to several persons doses of 1 to 4 grains of S. from S. tuberosum and nigrum, no symptoms; afterwards took 6 grains; 3 a , same, persons took 15 grains.

MIND

• Stupefaction without previous excitement, 2.

HEAD

• Vertigo, 2, 3a.
• Head hot, heavy, dull painful, 2.
• Heaviness of the head, 1.
• Pain in the occiput, 1.

EYE

• The pupils were not much affected, perhaps somewhat contracted, 1.

MOUTH

• Salivation, 2.
• The pure alkaloid has a cooling, acid, and salt taste, and when chewed, it causes a glutinous sensation in the pharynx and throat, with scraping, which extends down to the stomach, where it becomes a peculiar sticking pain, 2.
• Bitter taste, 3.

THROAT. [10.]

• Scraping in the throat, 1, 2, 3a.

STOMACH

• Constant eructations, 2.
• Nausea and diarrhœa, 3a.
• Nausea, and violent ineffectual efforts to vomit, 2.
• Nausea and vomiting, 3.
• About 5 P.M., vomiting three times without previous nausea, without pain and without any intestinal symptoms, 1.

ABDOMEN

• Rumbling in the abdomen, 2.

URINARY ORGANS

• (The next morning, examination of the urine showed albumen!), 1.

RESPIRATORY ORGANS

• Hoarseness, 2.
• Respiration slightly slower than natural, temperature not affected, 3a. [20.]
• Very superficial slow respiration, 15 or 16 to 14 to the minute, 1.
• Difficult respiration, with oppression of the chest, 2.
• Oppressed respiration, 1.

PULSE

• Pulse increased in rapidity, weak (72 to 88), 1.
• Increased frequency of the pulse, sometimes as much as 25 beats, lasting four hours (the next morning, somewhat slower than natural), 2.
• The pulse ran up to 95 and 100, was remarkably soft, small, and weak, 1.
• Pulse rose from 76 to 92 in fifteen minutes; in twenty minutes more it returned to the normal, 3a.
• It caused after ten hours slight slowness of the pulse and respiration, but no change in the temperature, 3.
• Pulse small, weak, thready, 2.

INFERIOR EXTREMITIES

• Slight tonic spasms of the lower extremities, 2. [30.]
• The next morning the prover felt quite well, with the exception of some weakness in the lower extremities, 1.

GENERALITIES

• Weakness, 1.
• Sensation of great weakness, 2.
• Sensitiveness to light, noise, and to touch, 1.

SKIN

• Skin dry, 2.
• Hyperæsthesia of the skin; creeping along the spine when touching the skin; more easily tickled than natural, 2.
• Itching of the skin, 2.

SLEEP

• Frequent yawning, 2.
• Great sleepiness, with inability to sleep, 2.
• Sleepiness, 2. [40.]
• Sleep very restless, frequently disturbed by frightful dreams, 2.
• Sleep frequently interrupted during the night, but without dreams, 1.

FEVER

• Extremities cold, 2.
• Profuse perspiration without weakness, 1.