Sepia officinalis

Volume IV — Main text

SEPIA. The dark brown paint secreted by the cuttlc-fisb, Stpia officiiuUh.

1. Provings. — I. Hahkemann, C/ir«/i;f Z)/«aj«, part v of original -^ vol, of translation. Contains 1657 symptoms, of which 160 ar^^ from five fellow-observers.

2. a. I have myself observed certain effects of S. I used the 3"::^ trit., intermingling some doses of the I2th dil. The action of ch^^ drug showed itself in a peculiar fermentation of the blood, slight fever-^v disagreeable sense of nausea^ ebullition in all the vessels, heat at stomac' and \\ the lungs, noises in the ears, troublesome dreams, determinatio of blood to head. But the most remarkable effect was the being awakened with a start by violent beatings of the heart, slow and regular as in hypertrophy, felt strongly in the head, and producing a slighi feeling of anxiety. After about a m. this ceased abruptly, and it fell as if the cardiac pulsations were entirely arrested. I anxiously soughc::^' to feel the heart beat at its normal place, and did not recover calmness-^ until I had felt it return under my fingers. This was at 4.30 a.m.

b. I had taken the previous e. a dose of the 4th dil., and had felt a contractive sensation in forehead, followed by peculiar itching there Next m. I found at same spot a vivid rose-red eruption, formed of little, round spots encircling like a coronet the roots of the hair. At ix it was still visible on the r. side. On the chest, where I had felt similar itching, little yellow spots appeared. (On another d. I experienced persistent irritation at nucha, with sensation to touch as of the presence of small elevations,) The itching was considerable, very tlifferent from that caused by insects, returning instantly after scratching ; it seemed as if the finger were unable to disperse the ebullition of blood concentrated at this point ; it gave me the impression of an internal irritation without external cause. 1 experienced also at the apex of the chest sh'ght drawing pains, which went immediately to the forehead, becoming there dull and pressive in character, I felt also great feebleness of legs when walking, and a general moisture in the aiimcDtary canal. (K.ruger, Bibl. Hom.^ Aug., 1878, p. 235.)

1. Miss K. de G — , M.D., healthy but delicate, took from Dec. 5th, 1874, 3rd trit. n. and m. for a week. On 6th had 4 stools during d,, with slight pain in transverse colon and some tenesmus. (Bowels were always remarkably regular.) On 7th d. still pain in colon, and stool

• Brunton's account of tlie action of Saponin, based 00 Ave other authors besii iler, addt nothing to the above — Eos,

little^ :lt a^

ahotit every 2 h., natural till p.m., when it became diarrhceic, with tenesmus before and during it, and afterwards burning of anus and intense feeling of bearing down of rectum. On 8th no action of bowels. Several pimples appeared on cheeks and wrists, very sore, pustular, like chickcn-poclc Constant hunger, chiefly for sweet things and meat. From 8th to lOth there was headache on waking, better after moving »bout; and sleep was unrefreshing, leaving tired aching feeling all ihiough body. For lo weeks after proving this last continued, also constipation, pimples on cheeks, and continual hunger, especially for eii. (This proving was conducted by Dr. W. Owens, who saw over daily. The above is her own record. To his interrogations he adds that she had pain all over bowels, with sense of fulness and ireness; pricking at seat of eruption before pimples first appeared, nd burning and soreness in them subsequently. When they opened, blood ind pus were discharged, and pitting remained. She declined to repeat proving with a higher potency on account of the annoying eniption.) {Trans, of Amtr. Inst, of Horn., 1875, p. 177.) ^K 4. a, J. F. Frantze, student, took 3rd trit. every 3 h. from Nov. 1st. ^Piitt lymptom noted occurred after 4th dose — a peculiar wave-like Jcnution extending through body, and down arms and legs to near their extremities, then sudden expansion with sharp rheumatic pain, *t:ng but a m., and then subsiding. On 2nd d. pains in various of body } severe pains over eyes, alternating from one to the Other; swelling and burning of eyes, to which a flow of tears affords Jief. Later, itching in various parts of body, relieved by scratching, iftcr which there is pinkish colour; pain constantly between shoulders nd down back ; stiftness of back of neck ; inclination to sigh ; profuse Ruse-blced several times ; intolerable itching inside nose, which is sore I scratching.

♦. On 5th began to take 30th trit. (no information how). Wan-

Fwiog pains, especially drawing and expanding pain at side of neck j

P>in in hip, worse on walking; dull and drowsy; full feeling in head.

(/w.,p. 179-)

1. William Dietz, student, proved 3rd trit. Nov. 2nd, took 4 3.30 p.m., heavy pressing pain over 1. eye, extending towards

i of head. 4, sense of great fulness deep in 1. orbit ; headache conwd to I. side, better in e., increased by shaking head, better in open 3rd. — Woke at 7 a.m. with darting-pressing pain in r. eye, last- ; about 15 m., when it changed to 1. eye ; occasionally darting pains Bm L eye over side of head to occiput. Took medicine f times to-d. »avv prcssive pain or fulness all d. in I. orbit and head, with occa- 'onif darts j better after meals. 4th. — Felt well on waking at 7.15. About 8 had some pain as yesterday, and it lasted all d. ; both eyes heavy, with tendency to keep them closed ; indisposition to mental l»bour, which aggravates headache. 5th. — Same doses and same headthe. 6th. — Took 6 doses of 200th dil., but though he awoke with headache, it had gone by midday, and p.m. he felt quite well. Repetition of latter doses 7th to loih produced no symptoms, [Ibid.., p. 181 ."^

1. a. E. Cranch, M.D., xt. 2j, in perfect health. Urine "\n ^— sr quantity about 40 oz. j $p. gr., a.m. 1029, p.m. lOll.

I ok. rwaj \ k., h y lining it ne

ater a Sew h. a white fUi , «r bf acxoc add ; but nit pvoved Bohmt to HWQ. xocfa.— Ur

t iLM^ 1031. At 9.70 a.iiu.

oat I ia.lMck from bead

Hei

:40gF-'

8.30 and II p.(

1331,

found

adlMTcnt film.

tirfai

(-tfcyi

rao^]

He;

Ben

MHxplioasi tikis m. (l$t I 8.1; a.m.

macm nok jo p. At 9.4^5 plsl d^jht ddl WadarV through both KafiES« aal tired fcc^ag; da^faig m. MKana ■riaariin. i6th. — tJnae of hit a. k» a Waij wkiK depone, ihoariag shdc characters as hdbve. H^kBmkteke^imwmaammmaamtpa^tomxiaait, At8.15a.n1. faaed 15 ok. of nae, a^ p'. xtm. At 9^45, luTiiig been constipated aace (41k, a saddca viokat ada^ ia aaas came on, and condaaed (icfiewed bf 6at waB^iag) ifll wbca fieoB b«a to psB. Slight adaagMaeckof hiaMerjattafegyaactaiAtiui^aadtMigKng in urethra sMgbK Cwiigcs of hrrfirbr in odes of head ; unacof aiaiiiia | hmapj feeling in stomach as soon as s Ik «fcer a aKd i ifi^jhc achtag ia r^;iaa of kadnejs. On 17th and iSiii some lia^g in aRdaaioa 191k wdL (/U^p.196.}

y. IX. CSyfrnssMMJaarr gare 3ni trit. to 5 wtimen students,

a. ]fiMA.S.ly| — » taking i4gr. in 5 d>, had no symptoms whatever.

. Min Jdua H. S— , whose ** general condition was exceedingly hagoid in the mocaing,'* took dnig for 4 d., and after 2od d. experienoed iinmasl ckarncas of tntelkct, greater strength, and general fediag of iw«-^rr.

r. aln. M — took drag oooe or twice a d^ April 23rd to 25th. On m. of 24th Ceeiing of prostration and ■'■ goneness,' principally in stoqsach ; cravii^ for food ; inclination to take a long breath ; sense of we^kt in chest as trom outward pressure -, e-erTthing seemed an exertion. On 25th same prostration, and n. was disturbed by unpleasant dream*. On m. of May 21 st took another dose, and reports, " Tired feeling all over. Lasting all d. Prolapsus uteri, with inclination of ftindus to 1. side, producing a numb feeling in entire lower half of I. side of body, with constant dull aching there and in pelvic region, Utter somewhat relieved by recumbent posture, especially when lying on r. side. Tenderness of 05 uteri." On 23rd took another powder, and had same symptoms as on 21st, with — in addition — sharp piercing pain in lower lobe of r. lung, coming in paroxysms, and so severe as almost to make her cry out.

^/. Miss C. H — took same at n. for a week. No symptoms save general clearing and improvement as in 7 h.

f. Miss Caroline A. H — "has suffered from enlargement of the

Womb, 'a tumour cured by galvanism' at our hospital." Had not

menstruated since February. She took a dose at noon, April 21st. In

40 ra. hot flush over face and whole head^ lasting but a few seconds,

instantly followed by slight perspiration, and that by headache in r.

head and face, not severe, but with surging sensation in forehead, like

waves of pain rolling up and beating against frontal bone, i.30, pain

"1 r. head more severe. It somewhat abated after dinner, but increased

again 10 m. later. 2.45, flush over head, with great increase of pain,

which extended somewhat to 1. side. 4, pain less severe. 5, slight

flush and perspiration, and slight increase of pain. Headache lasted till

she went to bed, with — in c. — feeling in nostrils as if she had taken

cold, 22nd. — At 7 a.m. took 2nd dose. Headache returned, but not so

Violently ; also burning pain in nose, especially at rest. From 10 till

Spain in forehead became severe, extending to malar bones, with heat

'_" ferchead, pale face, eyes feeling tired and looking injected. She lay

"Wn from 3 till 6, and slept ; headache relieved thereby. 23rd. — At

9«.ni, took 3rd dose. At noon some pain in head and face, but not

"marked unless she thinks about it, when it is quite severe. At 6 p.m.

(flush of heat in face and head, followed by perspiration on same parts;

jnfadache abated. 24th. — Some headache on rising, and a general good-

ror-nothing feeling. Took 4th dose at 10 a.m. At 11 flush in head

*nd /ace, with perspiration. General dull heavy headache ail d., with

paiior of face ; eyes tired and red ; sensation of bearing down in pelvic

"■fgiora, with slight dragging pain from sacrum. 25th. — No medicine j

""t s^me dull headache, pale face, tired and reddened eyes, and pelvic

jymptoms, as yesterday, with inactive bowels and constriction of

sphincter ani, 26th. — Headache abating j pelvic symptoms worse —

mor^ weight and bearing down, more pain extending into loins and

down thighs in front, with constriction of sphincter hindering action of

bowels 27th, — All symptoms abating. Those of pelvic region lasted

longest. On May 9th took dose at 12.30 p.m., and repeated it daily

till I 8th, 9 p.m., colic in upper abdomen j abdomen hard and distended j

|orcness and pain in sacra! region of back. 10th. — Abdomen same, and

^nde^r to touch; sacral region do., with sense of bearing down; some

"™ in forehead and stinging in nostrils, as from a cold. 9 p.m., dart-

'"g. Plains in vagina, 1, side, from below upwards, iith.— Slight colic

" '^g d. J 2th, 10 a.m., desire for but inability to pass stool ; intense

''^"^ t: riction of sphincter ani. 3 p.m., hardness and tension of whole

abdcknien, with flatus and occasional colic ; weight and bearing down in

P^'^*s. 13th. — Weight and bearing down in pelvis and tension in ab-

flotr^^P . verydifficult movement of softsmail stool, insufficient, with con-

stam urging; some flatulence. 14th. — Pelvic and abdominal symptoms

'he Same ; pains in hips and thighs, extending to near knees ; stool soft,

$mai^ insufficient, with great straining, followed by heaviness in abdo-

•n^^ and aching in pelvis and thighs. 15th. — Stool as before, and bear-

itv& down ; other symptoms not marked, 1 6th. — Abdominal and

pC'Vic symptoms the same ; constriction of sphincter to-day so intense

as utterly to prevent stool, 17th. — On rising pain in sacrum and

bc*ting down, with some yellowish leucorrhceaj which later became

too

profuse, creamy, and slightly bloody. There was pain in abdomen and back, extending down legs, as at menstruation ; and the same ineffectual urging to stool. i8th. — Symptoms better in m., but returned in e, Sphincter was less constricted, and a small stool occurred, igth. — All hypogastric symptoms continued -, some glairy, amber-coloured, slightly offensive, occasionally bloody leucorrhcca ; constriction of sphincrer gone, but no stool or desire for it. 20th. — Stool free, with little straining i abdomino-pelvic symptoms continue, with lassitude in lower limbs when moving, and slight frontal headache. 21st. — Pain aai tenderness in abdomen ; pain in back across hips ; some bearmg down; < sanguineous leucorrhcea, in gushes, but not profuse; headache in fore* 'head and below temples. (Here the record abruptly stops.*) (/W., p. 198.)

1. Dr. C. Wesselhceft also instituted some provings on i female and 7 male students with the 30th trit., of which a grain was ukcn n. and m. for 3 — 5 d.

a, ^, d and e (the woman) had no symptoms whatever.

f, after l gr. at retiring and one the next m., had, p.m., burning heat in throat, with fulness and pressure in head ; this gradually increased to a severe frontal headache, most severe over I. orbit. At n. took i g'with increase of symptoms ; also tightness and constrictive sensation >• chest, and hard, dry, concussive cough. These troubles continued 4 — 5 d. He repeated medicine several times afterwards, with sattt effects.

/ took 1 gr. at 8.30 a.m. 2 p.m., face flushed, nose dry, ever)' symptom of cold in head, which felt swollen ; sleepy, and must li' down, which relieved him. 3, repeated dose. Late p.m., stuffed nose '■ e., watery mucus from nose ; slight frontal headache, passing round t. side to occiput ; voice like that of one with cold in head. All symptoo^'' gone next m.

g began, Nov. isth, by taking a gr. n. and m. After 3 d. he took * gr. every n. till the 30th. On e. of [6th had severe headache, outward' pressing in temples, which continued till next m. (He had had simil*'' headaches after strong coffee, but was taking no coffee now.) O" 30th, 10 m. after taking nightly dose, felt dull pain in r. upper chcs*' then boring pain in I. testicle, finally pain in r. groin. This last remained constant, while the other two came and went at short interval till he fell asleep. Nothing more was felt.

h took I gr. on n. of Nov. 14th and on m. of 15th. About 2 p. had severe pain in a spot about ij in. in diameter over spleen, dec ^ This continued till 3, when he began to have flushed face and di*' frontal headache, with pulse of 100 — 1 10. 4.30, very hungry, but aftc^' a little food was satisfied, and stomach felt full ; pain was relieved, an<Jt

• We have given these provings of Dr. Wesselha?ft's because they are his; bu' besides the obvious fact of a giving negative, and b and J merely curative results w"^ are not satisfied about r and e. The abrupt termination of the latter's narrative i" paralleled in the former's, and in that the pelvic changes are no less abruptly inlrc duced. We are told nothing, moreover, of e's previous uterine health ; while the slight and vague account ot'e's is just enough to raise doubr as to the purity of symptoms arising in this quarter. The provings must be regarded as given for confjinijlion rather than with any endorsement on 01 ~

^

SEPIA. loi

feeling drowsy, he slept till 7.30, On awaking, pain was in lumbar tegjion, more on 1. sidej dull aching was felt there all n. i6th. — Pain in Imns better to-day, but far from gone. L. eye ached badly p.m., with dimmed sight as if mist was before it ; pain ceased in e., and then came feeling as if head was stuffed. 17th. — Both pains again to-day } dtat over eve, coming on p.m., kept him awake a long time after going to bed. 1 8th. — All symptoms decreased, but general languid feeling. 19th.— Pains gone ; but he felt all d. as if he did not care what happened. [IhiJ.^ p. 182.)

9.* a. W. A. French, in good health, urine 28 — 30 oz. daily,

gr. 1022. On Jan. nth, 1875, took 200th dil. every ^ h. all d.

rine 20 oz. only, sp. gr. 1027 ; on standing it clouded, and deposited

white sediment. From 12th to 15th it was 23 — 24 oz., sp. gr. 21 — 24,

clear and without sediment.

i. On 1 6th took 30th trit. all d. in same manner. Next d.'s urine was 19 oz., sp. gr. 1028 ; on standing, brick-dust sediment formed, and vessel was coated on sides with a white sediment, making glass look as ■Aground. Last n. restless, from very distressing dreams ; saw mice, '3^, and snakes; heard noises in street, and people talking, running, &c. loth.— Again could not sleep from sights he saw and noises he heard ; 'oned about in bed. Urine 19 oz., sp. gr. 1027, bad odour, deposit of "eeperred; smarting of urethra while passing it. Could not keep mind on books or follow lectures } moody feeling. 19th. — Similar n. Urine I '* oz., sp. gr. 1023, looks healthy and gives no deposit. At 9.30 f P-pi. dull pain over both eyes, seemingly in bone. On 20th, 21st, 22nd, '■ '"*'»e was 24, 28, 31 oz. } sp. gr. i02i-2 ; otherwise natural.

c. On 23rd took 30th again in like manner. At noon passed water, J^ich was clear, sp. gr. 1026; but after standing 4 h. there was brick- ""st sediment, and sides of vessel were coated white. At 9 p.m. urine f^ 1034, flocculent when voided ; and after standing 2 h. there was ^PQsit and coating as before. He had same restless feelings as on l^^h. On 24th his mind wandered very much, and be felt moody and

"•"esseo. , There was at no time any change in pulse, resp., or temp., and ^^els always acted daily. (7^/V., p. 184.)

1. Alfred Wanstall took same every i h. — 3 h. from Jan. ^^b to 22nd. Quantity and sp. gr. of urine were noted daily } first l^kand latter rose till 21st inclusive,on 22nd and 23rd reverse obtaining, .'^thing is said of deposit, &c. 17th. — Teeth sensitive to cold air. ^11, tired pains about back and neck, specially r. side. N. restless. ^^Ii. — Same pains about back and neck, also in r. forearm and thigh, ^^r r. eye, and in forehead. 19th. — Slight frontal headache off and on ^ting this d. and next, specially on I. side. Back and neck pains felt >^Casionally. Great sensitiveness to cold. {Ibid.^ p. 186.)

2. H. H. Tinker observed his normal state Nov. 4th to 15th,

^d found temp. 97*'— 98° ; pulse 72 — 80 j urine about 6 oz. 5 times

"*Uy, sp. gr. rather high, 1028 — 1030 (p.m.), normal otherwise. Dec.

15th, took 30th trit. every ^ h. from 6 a.m., being then perfectly well.

• The following provings, to the 1 3th, were conducted by students under the Xiperrision of Dr. Alien of New York.

l6th, — In e. head felt heavy on r. side. 17th. — Feeling, a. side of head, nose, and throat as if he had taken cold ; thick ye discharge from r. nostril, which on putting finger into nose becc bloody ; r. eye looked red and felt sore \ head stupid, cannot remen or do any real mental work ; pulse 90. No stool since beginning d 2 p.m. very severe headache from r. to 1. temple, extending into and nose, all feeling as if raw. 4, weakness about pelvis, fore back, and dragging pain round anus. In e. hoarseness, and si swelling of r. parotid. Urine all d, high-coloured ; passed 3 ti only, and in smaller quantity \ sp. gr. 1030. Pulse 80 in e. l8tl Yellowish-red deposit adherent to sides of chamber in m. ; sore fee at anus ; profuse yellow discharge from nose, with epistaxis after m and raw feeling constantly ; felt irritable, and found it hard worl fix mind on studies. In e., besides these symptoms, and the for headache through temples, eyes felt very sore as if bruised, and he great weakness with some pain in r. sacro-iliac region. Bowels confined ; urine deeply red, 4 oz. passed three times, sp. gr. I all d. 19th. — Throat still feels " skinned ;" great dragging on mi ment in r. sacro-iliac region, with dull heavy ache constantly. I feel very dry, and crack. No desire for water even at mealed! Mind as before. Urine very scanty, deep red, sp, gr. 1030. 20t] Throat the same, hip and back easier. At last a stool, cau painful raw feeling in anus. Nausea all m., and distaste for fc tongue coated brown with red edges. Mind still stupid, and inci to worry. Quantity of urine to-day not mentioned, but sp. gr. i was 1025. 2ist. — Tongue yellow coated at middle and back j tip edges red. Thick yellow discharge from nose ; both ears ki\ i plugged, and he is a little deaf. Back still aches, and causes nil and faintness on standing. Urine very scanty, giving red coatinj glass ; sp. gr. 1025. 22nd. — Same in m. ; urine very scanty and h coloured, but sp. gr. only 1022. In e. head and throat were imp ing, but back still uncomfortable. Symptoms now gradually di peared, but urine remained very dark red up to Jan. 4th. {Ibid.^ p. l 12. S. B. Barchet, art. 31, nervous temperament, in good he but not robust. Observed sp. gr, of urine from Nov. 7th to Dec. I and found m. average 1020, e. 1023. Temp, was subnormal, 97 9S'' m., g6° to 97° e. Dec. 14th to 24th, he took small doses of: trit. every h. 14th. — I h. after 1st dose shooting in a r. upper m< During 2nd h. heaviness in forehead and temples; dizzy, unst( feeling when getting up to walk ; smarting pain in urethra. 15U Going into cold air in m. caused great discharge of tears from r. ■

going oft' in warm room. Dull pain in upper 1. lung. 17th Shoo

in 1, molars and in finger-tips, a,m. Again dizzy on rising to wi weakness and weariness in all joints, especially knees ; headache d., worse 5 to 6 p.m. i least movement of head causes dizziness, tm ment from side to side produces feeling as if brain mass were swa] to and fro, 5 p.m., a slight chill. 6, flashes of heat, skin get slightly moist ; shooting pains along inner side of whole r. arm. gr. of e. urine 1032. 18th. — Long-lasting pain under r. shoulc sharp pain along canal of urethra ; smarting pain on outer

hand. SUght nausea after lunch. 19th. — To-d. urine high-coloured, quickly becoming turbid and staining bottom of vessel. Sp. gr., e., 1030. Nothing specially felt till 5 p.m., when he had occasional stitches along urethra, stitching-smarting pains in I. knee and on inner side of thighs and arms. 20th. — Nothing special during d., save lame feeling in joints and stitching pains in temples ; these last very marked on lying down at n. Sp. gr. in e. again 1030. 21st. — Same pains as yesterday, more severe on 1. side. Sp. gr., m. 1028, e. 1030. aand. — Severe shooting in 1. temple from noon till 7 p.m., also higher up on side of head ; repeated shootings in heel ; sour eructations. Old symptoms reappeared towards e. Sp. gr., m. 1026, e. 1032. 23rd. — No new symptoms. 24th. — Sharp shooting through heart, like an electric shock, at noon. He now went away till Jan. 5th on vacation, but frontal headache and pain in temples came on daily ; mind was slow and dull ; urine continued high-coloured, became turbid quickly, and showed in m. a fine reddish sediment. He could not take sp. gr. while away. Jan. 8th. — Sharp pains in finger-tips, upper incisors, and eyes. 9th.— Unpleasant exhalation from body on getting warm in bed ; flashes of heat all over body about 8.30 p.m. 12th.— -Sp. gr., m. 1028, e. 1030. Pains in various parts came and went for next fortnight ; and from the 14th he had a vesicular eruption on scalp, chest, back of shoulders, calves, and knees. Some of the vesicles became pustules, and when squeezed yielded a tough sticky matter ; but pressure was painful and made them look angry. Those on scalp itched. Sleep, hitherto good, was now restless. Urine often scanty, and then there was some vesical irritation. {Ibid.^ p. 191.)

1. a. Mrs. A. G. S — , xt. 32, mother of 3 children, with fine

delicate sensitive skin which chafes easily. Dec. 9th, 1874, took 2 gr.

of 30th trit. at 9 p.m. Slept well till 4 a.m., when she awoke with

sense of fulness in transverse colon ; felt warm all over, perspiring on

(^t and neck j veins feeling full and ready to burst ; seemed as if she

could not move. Took dose of aconite, and in a few m. went to

sleep again. loth. — At 10 a.m. repeated dose. 4.30 p.m., sensation

^ if upper abdomen were bloated, with feeling as if something were

moving about there. Hard stool at 6, faeces covered with slime}

slimy bilious stool at 8, and again at 11. Slept well all n. nth. —

A distinct chill at 9 a.m., followed by fever with chilliness across

stomach and bowels and between shoulders. Urine thick, slimy, and

very offensive, depositing yellowish pasty sediment on standing. Sweat

following fever was also exceedingly offensive and pungent. The

sense of fulness in abdomen continued 5 d., without other symptoms,

'^ve that she remained languid, and was troubled with offensive sour-

smelling gaseous eructations.

i>. On 19th, at 3 p.m., Mrs. S — took another dose. One h. after, ^Idness between shoulders, then general chilliness over body, followed oy sudden loss of strength and weakness about chest, and she broke put into profuse perspiration over chest and neck ; hands and feet ''^'^e cold as ice, face pale } she thought she should vomit, but was relieved on getting up and moving about. She bad pain and foreness throu^ bowels all e. ; slept 10 — 1 1, and then woke, feeling a« if a

load was resting across epigastrium. After a dose of aconite she slept till m. On 2oth she had a fine rash over body, particularly about bends of elbows and knees, attended by priclcing, tingling, and itching. While in a warm room it remained out, and she felt well ; if she went into cold air eruption would disappear, and she would then have severe rheumatic pains about these joints (elbows and Icnees). The rash, with these characters, remained some time, extending to axilla: and groins ; when it reappeared after suppression by cold, profuse sweat accompanied it. [This lady proved under the superintendence of Dr. Owens.] {Ibid., p. 174.)

1. a. A. J. Sherman took, Dec. loth — 17th, a grain of 30th trit. every h. At end of week he had severe itching on r. side of pubes, worse at n. on going to bed ; becoming moist after scratching, and forming a thin scale easily pulled off. By the 28th this eruption had nearly disappeared.

b. On Jan. 14th he took 5 one-grain doses at hourly intervals from 1 p.m. At 8 p.m. a sharp pain under ensiform cartilage, as if a nerve were made tense, in a spot that could be covered by end of finger, worse from inspiring and going upstairs. Heart's impulse and rapidity were increased, especially during inspiration. (He had occasionally in the past noticed slight irregularity of pulse.) 17th. — Pain and disturbed action of heart have entirely gone off, but eruption on pubes, which had almost disappeared, has increased. {Ibid., p. 195.}

15.* L. A. Snyder took 30th trit. every 3 h. from 5 p.m., Oct. 31st, to 10 p.m., Nov. 1st. On latter d. slight dull frontal headache, which lasted 2 following d., on which also there was unwonted inclination to wonder over future events. This mental state lasted into next d. (4th), accompanied with dull, stupid, sleepy, confused feeling in head ; dulness of comprehension ; inability to collect or express his thoughts. On 5th took medicine every ^ h., continuing it till e. of 10th. Only effect produced was, on 6th, slight itching and soreness in 1. outer canthus, which on 7th had increased and spread ; on 8th upper lid was much swollen, eye half closed ; lower lid also oedematous, as if stung by a bee ; lids sore to touch and on closing eye \ slight itching. By nth eye was better. Throughout proving there was distension of stomach after meals, especially supper. {Ibid.^ p. 177.)

t6. a. C.Franklin Manson took joth, manner not stated. Burning pains in dilFcrent parts of body, especially in I. hypochondrium ? great itching of margins of eyelids; tongue white-coated ; small white blisters inside cheeks; tip of tongue feel* as if scalded ; great dryness of lips; stitching in anus.

b, Same took aooth dil. Sores on septum nariuni ; disgust for tobacco after smoking. Three or four d. after leaving off medicine had radiating pains in back of neck and occiput ; and, later, alternate cold hands and feet. (IbiJ., p. 179.)

1. J. W. Bechtel, jun., took a dose of looth on Oct. jut. He experienced nothing extraordinary till Nov. 4th and 5th, on which he had short-lasting rheumatic pains in insertion of r. temporal muscle and t. shoulder-joint. On 5th took dose of 30th. On 6th and 7th sudden stitching pains, leaving more gradually but very soon, in 1. palm, I. lung, and r. foot. Appetite impaired while taking medicine. (IbU., p. 178.)

I I

• The provings from the 15th to the i8ih were instituted under the direction of the late Dr. Farrington.

1. W. H. ToMLiNSON took sooth at times between Oct. 31st and Nov. 3id. In 14 h. after ist dose sense of fulness in 1. axilla, after a few m. shifting to r. side. An h. later, while walking, same sensation in r. groin, soon passing o<F. Nov. ist. —In e., after walking in cold wind, had sore, rough, burning feeling in eyes, aggravated by gaslight and on attempting to read. 2nd. — Headache all d, with great mental depression ; cannot collect thoughts or recall things he knew very well. These qrmptoms passed off by noon next d. ; but sense of fulness returned i — 2 p.m., first in 1. axilla, then in r., then in groin, as before. On 5th resumed medicine, taking a dose at 3, 5 and 7 n.m. Mental dulness in afternoon; sore bruised feeling at r. of tip of nose and c^j, also in 1. elbow. 6th, — Continued medicine till noon. Sensation in nose and cMu increased ; spot on nose was quite red, but there was no point. 4— 5 p.m. sev.-re headache, beginning at root of nose and going to temples; It passed off in e., with nose and chin symptoms. On nth, and slightly on 12th, sharp stitching pai% in prepuce and frenum,with smarting raw feeling as if abraded ; nothing found b'at some redness. Still occasional uneasiness in axillae. {Ibid., p. I So.)

19.* Mis' E. F. S — proved 200th dil., taking a doses Nov. loth, i dose on aist, s doci on 2snd, and i on Dec. loth. A long array of symptoms set in, chiefly of Jie pelvic organs and the nervous system, and continued till Dec. 20th. Several 'jmes after this, especially when for other symptoms she had occasion to take a dosr of nux vomica, the sepia symptoms recurred, lasting some days each time. (2W< ., p. 157.)

so. Miss M. E. K — proved same, taking a dose Nov. loth, nth, and i6th, .xid Dec. 4th, with a similar result. The record of symptoms extends to Jan. 24th. She, too, found symptoms recur (Feb. 28th) after a dose of nux, (Ibid., p, 164.)

»i. Mrs. , aet. 41, widow with 3 children, catamenia regular but scanty and

dark, in excellent health, proved same, taking a dose every h. from 10 a.m. to 3 p.m. on Jan. 5th, » doses on 8th, 2 on 12th, a on 24th, Pelvic and nervous symptoms set in as before, but latter were on the side of depression instead of, as in No. %o and (partially) No. 19, on that of excitement. Pelvic symptoms were still present on Feb. 13th, when the record ceases. The next menstrual flow was brighter and more copious. [This lady's report is furnished by Dr. Emma Scott, who vouches for the healthy condition of her uterus at the beginning of the proving, and adds that " when the leucorrhcea began" she examined her and found " uterus congested and a yellowish discharge pounng from it, beginning to prolapse, slightly displaced." Nothing, however, is said in the daily reports of the occurrence of any leucorrhcea.] {Ibid., ^. 171.)

%. Mr. H, Robinson gave a young woman, every 3rd m., a teaspoonful of a sol. of I gl. of 30th in ^viij of water. She had had a leucorrhcea for a very long time, and this left her completely during the proving. After 2 doses she had depression on waking in m. ; extreme nervous restlessness ; ftontal headache ; eyes heavy, lids inclined to close ; dry throat, with sense of thickness ; taste very mawkish — sour after eating; no appetite ; first relaxed bowels, then constipation; urine thick and turbid ; anxious oppression in upper chest ; strange tickling in lower chest ; pain and weakness in small of back ; weary pain in I. shoulder-joint ; fatigue and power lessness of both arms on waking; bruised aching in sockets of shoulders extending to elbows — intermittent, and generally only in one arm at a time ; feeling as of weight pressing on thighs — momentary ; very restless sleep; she is quite hot, then cold, with great feintness; m. perspiration, sometimes hot, sometimes cold, particularly in hands and feet ; constant disposition to sweat, both n. and d. Menses came a week too soon; were scanty, and lasted only i d. {Brit, Joum. of Horn,, xxv, 33 lO

1. Another young woman took, of a similar sol., a dessertspoonful each m. After 7 — 8 d. sad and discontented with everything; pressive headache at vertex ; eyelids heavy, with much frontal pain ; feeling as of a painful sore at tip of nose, followed by an eruption at spot, lasting 2 d. ; constant sneezing for several d. ; wrenching pain in all molars ; bleeding from gums at slightest touch ; lips sore, smarting, and disposed to crack ; cutting pain in throat, with raw feel and much phlegm ; tickling scraping, and again loose phlegmy, cough ; pain in both sides of chest, passing round to between scapulae ; intolerable aching at coccyx just before

• Nos. 19 and 20 are furnished by Dr. A. K. Hills.

ro6

action of bowdn (several times) ; aching acrou loins, wonte on noTcment; twisting pain in r. knee, and drawing pain on inside of r. thigh ; dry burning »«n»rton w Miles ; burning swollen feeling of feet ; very heavy and drowsy ; restless sleep, tvidi conliited dreams; flushes of heat, she feels in a kind of glow, then chills j profuK perspiration after coughing j sick and feverish all d., with thirst; heavy sweat, a* from a told ; hard and inflamed boil on r. natis ; feels weary, and trembles all ovtr, (\fense$, which were usually accompanied by cold aching pains in lower bowels came on without the least distress.) (/A/V.)

»4. Another took i gl, of 30th dry on the tongue each m. After $—6 d. setcrt pressure in forehead over r. eye; r. eye inflamed, with great burning and hchrynatiuD ; jumping aching pains in lower molars ; dryness and sorene-^s of throat— at n. if feels quite parched ; middle of tongue blistered ; stitches in I. hypochondrium ; ufiiic vinusually turbid ; pains in tendons of r, foot about ankle; swelling of feet, which burn and are very dry. (IbU.)

1. Another took i pilule ot joth a. and ta., and had foul and Hlthy ttttei ut different kinds; griping diarrhcea-like feel in abdomen, followed aftenvsidj l<> exhausting diarrhoea. (IbiJ.)

2. Another took same, and had cr«mp.like pain in calves and shooting pain in ill'iJ.)

A young man took same, and had intense headache, frontal and tempunl.

ankles. »7-

a8.

(No information as to dose, prover or time). Pressure and cutting in throji on swallowing, with much mucus in throat ; on attempting to hawk it up rlu' pressure, pincning and cutting are aggravated, as though the throat were cut wiib scissors, and blood comes; at same time confusion ot head, heat of whole Mji fever, pulse 108 j towards e. in an intermediate state between sleeping and wiking- At n. frequent waking with much mucus in throat and tiresome dreams. On rifing weakness, sweat on forehead, and nausea, so that he must lie down again imine>lii'c|y- Slimy diarrhoea 3 times, with discharge of a round-worms and ascaridrs. Mois-t cough as after a tedious catarrh, especially n. Cough with expectoration, unl ' Mime time pain in r. side of chest, especially violent on stooping and lying on t. s\ii^' Itching of nipple, which sometimes bleeds and seems to be about to ulctta^c- Yellowish -brown spots round neck, about a square inch in si«, which desquiW*' when rubbed. (GROSS, Archiv, xix, 3, 187.) ^i

1. Feb. 13th, took a globs, of 8th dil. — i4.th. Shooting pain in liver ^ kidney, pale face. — 17th. Accumulation of flatulence. — i8th. Same dose,— >? ^ Pain in gall-bladder, accumulation of flatulence, stretching with yawning, heavi^of bowels. — aoth — 24th. Very cold feet, frequent fever, much toothache, bur** ___^ on palate. — 15th. Same dose. After 4 '»• acute stitches in gall-bladder.— 16'''* ^ i8tn. Very cold feet, much headache, especially towards e. and m., also n. G*"^j,. prostration and laziness in all limbs.— ist — 3rd March. As la.st report. — j*- t„ Smelt at same dil. — 4th — loth. Very cold feet, coldness of all body. — 15th. Pai**^^ throit, shooting in uvula, both sides rather red, very painful when swallowing, la*'^| all d. and was very painful, with rigor and deposit of viscid mucus, which could •'--j be detached. — 17th. Coldness of all the body ; icy cold, sweaty feet ; icy coldnes*^ ^ stomach vvith borborygmus. — i8th. As yesterday, borborygmus when stretching^ , abdomen. Before a meal frequent belching with cold fechng in stomach, the bow^' feel tied up. Frequent fits of pinching pain in liver. Gall-bladder shooting ''* before, which is relieved by discharge ot wind up or down. After unusual stof'' a.m., of bright-coloured faeces in tnin strips, looking almost like porridge, soitie drawing pain in r. side, just above hip ; then extending up to ribs and down toward'' kidney, going off^ after discharge of flatus. — t4th. Got chilled in church, so that he could scarcely get warm again. After dinner violent toothache in r. posterior upper molar. Thence the pain spreads to sinciput, and lastly enters head, cheeks and both rows of teeth on r. side; it eocs off at n. in bed. — i5ih — i8th. Severe coryia, sore throat, chest feels raw, hcacT or teeth ache, especially after eating. As a rule had .seldom good appetite, often insipid taste, sometimes nausea. Had usually \ or 4 h. of good sleep at n., then frequent waking and restless tossing about, (^Ibid)

Volume IV — Appendix

SEPIA.

I. 7. #. Dr. Wesselhcbft informs us that the subject of this proving died a year or two later of cancer of the lungs, and that at the autopsy the tumour (a fibroid 6 in. in diameter) was found uncured. H.«t \aVi\s. •jrmptoms while proving S. must therefore be lecemdi -mx^ cvxosoicu