LACTUCA.

[Experiments with Lactucarium (the inspissated juice) are here included; the French Lactucarium is chiefly prepared from L. sativa, the German and English from L. virosa, the American from L. elongata. Fronmüller; Die Narkot. Arzneim, 1869.]

Lactuca virosa, Linn.

Natural order , Compositæ.

Common names , Poisonous Lettuce; (Germ.), Gift-lattich; (Fr.), La Laitue vireuse.

Preparation , Tincture (prepared from equal parts of the expressed juice of the herb and 80 per cent. Alcohol).

Authorities. (Nos.

1 to 37 , from Journ. f. Hom. Arzneim., vol. 2, collection of Dr. Ed. Seidel.)

1 , "S," provings with tinct., 10 to 30-drop doses, and with 3 to 4-grain doses of the extract; 1 a , same, effects of teaspoonful doses of the fresh juice of L. sativa; 2 , Ernst, effects of 20 drops of tinct.; 3 , Espe, 10 drops of tinct.; 4 , Theile, 40 drops of tinct., and 2 to 4 grains of extract; 5 , Piper, 16 drops to 1/2 an ounce of tinct., and 10 grains of extract; 6 , Henke, 10 drops of tinct.; 7 , Netolitzky, 4 to 6 grains of extract; 8 , Helbig, 40 to 120 drops of tinct.; 9 , Preu, 5 to 10 drops of tinct.; 10 , a girl of twenty-six, 20 drops of tinct.; 11 , a girl of fifteen, 20 drops of tinct.; 12 , a girl of sixteen, 1-2 grains of extract; 13 , a girl of nineteen, 2 grains of the extract; 14 , a girl of twenty-two, 2 grains of extract; 15 , a woman of thirty, 2 grains of extract, and 20 drops of tinct.; 16 , Andry, Traité des Aliments de carme, from the exhalations; 17 , effects of 10-15 grains of Parisian Lactucarium, Rothamel, Heidelb. Klin. Annal., 5, 2, 277; 18 , Tott, Lactucarium virosum, Rust's Mag., 43, 1, 138; 19 , Halle, Gift-historie, Berlin, 1787, p. 228; , Gmelin, Geschichte der Pflanzengifte, 1777, p. 486; , Vicat, Plant. vén. de la Suisse, p. 209; , Wibmer, Wirk. der Arzn., 3. 3, p. 301; , omitted; , Dioscorides, Mat. Med., L. IV, c. 55; , Plinius, Hist. Nat., xix, 8 et 18; , Silesius, Kräuterbuch, 1577; , Richter, Arzneim., 2 p. 605; , Kolb, Bromatologie, 1829, p. 209; , Burdach, Arzneim., 2d ed.; , Sachs and Dulc, Arzneim.; , Candon, Contr. Med., etc.; , Voigt, Lehrb. d. Pharm.; , Schrœder, Apothekerbuch, 1686; , Francois, Rev. Med., 1824; , Dierbach, Arzneikräfte der Pflanzen, 1831; , Glaser, in Brandes Archiv, 18, p. 252; , Ganzel, Diss. de Lactuca sativa, 1819; , Austrian Soc. Allopath. physicians, Zeit. der Gesell. der Ærz. zu Wien., 1847, provings with the extract, 1/2 to 30 grains at a dose; , Schroff, Lehrbuch der Pharm., experiments with 2/10 dr. of Aust. Lactucarium; , same, experiments on two persons with doses of 1 1/2 dr.; , Fronmüller, loc. cit., effects of doses of 1/2 to 62 grains of Lactucarium, Syrup. Lact. and Lactucin, in several cases; , A. Boe, poisoning of a family by eating a salad of L. virosa, Bull Gén. de Thérap., from Biblioth. Hom., Aug. 1876.

MIND

• Emotional.
• Lively mood (secondary action), 39.
• Merry delirium, which began about midnight and increased until morning; sang, jumped about on his bed, and played all sorts of antics (boy), 42.
• In the evening after grief, stupefying headache, violent contraction in the larynx, inclination to weep caused by the grief; though Lactuca seems to cause sadness with exalted fancies, so that the worst fears and apprehensions are aroused by the merest trifles (after twelve hours), 9.
• Internal uneasiness, anxiety (after eight hours), 6.
• Extremely ill-humored from the slightest cause (second and third day), 1.
• Fretful mood, with disinclination to work (second to eighth days), 6.
• She is fretful, excited by trifles, and aroused to anger (first day), 14.
• Very fretful but depressed mood (first day), 3.
• Peevish mood (first day), 15.
• Intellectual. [10.]
• Unusual disinclination to work, ill-humor; it does not trouble him in bed (second day), 7.
• Diminished power of thought (after a quarter of an hour), 22.
• Mental labor cannot be accomplished; the thoughts become confused; or no connected train of thought can be carried on (first hours), 1.
• Stupefaction, 40.

HEAD

• Confusion and Vertigo.
• Confusion of the head, 38, 39, 41 ; in morning (second day), 4 ; (second morning), 41.
• Confusion of the head, lasting twelve hours, 9.
• Confusion of the head in the morning, as after a debauch (second to fifth day), 1.
• Confusion of the head, in the morning after rising, with pressing from within outward in the forehead and orbits (after eight hours), 1.
• Confusion and dulness of the head (after one hour), 15.
• Somewhat confused in the head (after one hour), 7. [20.]
• The head is confused and heavy (second morning), 3.
• Confusion in the forehead (after one hour), 5.
• Confusion and a feeling of heat in the forehead (while bruising the fresh herb), 1.
• Confusion in the forehead externally, alternately more sensitive, now in the right, now in the left frontal eminence; on stooping, there is at times short transient stitching through the left eminence (second, third, and fourth days), 6.
• Confusion in the right side of the forehead, in the morning, for several minutes, 5.
• The head is befogged, dizzy, though without impairment of the power of judgment, 9.
• Vertigo, 40, 41 ; also from the exhalations, 18, 20 ; (from 10 to 15 grains of Parisian Lactucarium), 17 ; (from Lactucarium Genuinum), 18.
• Even the odor causes vertigo, 19.
• Vertigo; it suddenly became black before the eyes; the threads ran together while sewing; but if she looked off of her work for some time vision became better (after half an hour, and recurring several times during the day), 12. [30.]
• Vertigo in a warm room, with a feeling of too great fulness in the head (after half an hour), 1.
• Vertigo and heaviness, especially in the occiput (soon after taking, and lasting a long time), 1.
• Vertigo, together with heaviness in the limbs, 1.
• Slight vertigo (immediately), .

EYE

• Weakness of the eyes (soon), 1.
• Weakness of the eyes for a few minutes, during the first hours, 15.
• Slight transient burning in the eyes, 1. [80.]
• Biting in the eyes, especially in the external canthi, so that she is obliged to rub them much, which, however, makes them worse, 8.
• Biting pain in the left inner canthus (after one hour), 1.
• Brow.
• Transient griping above the eyebrows (after a quarter of an hour), 1.
• Extremely acute pressive pain in the glabella, lasting ten minutes (after ten and fourteen hours), 6.
• Lids.
• Margins of the lids covered with mucus (first and second days), 6.
• Slight burning in the lids during the day, while writing (first day), 1.
• Burning pain in the lids, especially of the right eye, with dimness of vision and dilated pupils (first and second days), 1.
• Ball.
• Pressive pain, with a feeling of tension in the right eyeball (soon), 1.
• Pupil.
• Dilatation of the pupils, 40, 41 ; (6 to 8 grains of Paris Lactucarium), 17.
• Pupils very much dilated ; in the boy especially the iris was almost invisible (second day), 42.
• Vision. [90.]
• Vision became dim, with burning in the eyes, 1.
• Weak dim vision (from frequent eating of lettuce), 24.
• Vision impaired; the eyes seem clouted, but the film disappears on looking intently at anything (after half an hour), 9.
• Vision is periodically and momentarily obscured by a slight film, in the forenoon (first day), 1.
• He seeks here and there before he can find anything (after a quarter of an hour), 7.
• After closely examining the capital letters in a newspaper he mistook M for P, and O for V, and the effort to read caused strong congestion of the eyes (boy; second day), .

EAR

• Alternating drawings in the ears, 1. [100.]
• Some dull stitches, followed by tension in the left ear (after ten hours), 1.
• Hearing.
• Slight humming and feeling of fulness in the head and before the ears (after half an hour), 15.
• Roaring in the ears, 9 ; (first night), 41.
• Violent whirring before the ears, in the evening in bed (first day), 1.

NOSE

• Frequent sneezing, which aggravates the chest-troubles (fifth day), 3.
• Catarrh, leaving soreness in the nose, with dryness, 1.
• A peculiar pressing-asunder pain in the tip of the nose, in the afternoon (third day), 5.
• A peculiar indescribable odor before the nose, with a similar taste in the mouth (first day), 4.

FACE

• Sickly expression (after several repetitions of 6 to 8 grains of Parisian Lactucarium), 17.
• Face pale, distorted, 18. [110.]
• Tense crawling sensation in the face (after a quarter of an hour), 1.
• Swelling of the lymphatic glands in the lips (second day), 9.
• Fine twitching in the lips (after eight hours), 1.
• Stitches extending sideways in the chin (at the exit of the submaxillary nerve), (after half an hour), 9.

MOUTH

• Teeth and Gums.
• Pains suddenly appearing in the left lower back teeth, a though a diseased tooth were twisted about, 8.
• Aching of the gum in a cavity while chewing (third to eighth days), 6.
• Tongue.
• Tongue coated white, 18 ; (first and second days), 6.
• Tongue thickly coated with mucus (from 10 to 15 grains of Parisian Lactucarium), 17.
• Constriction beneath the tongue (as after ink), (soon), 5.
• The tip of the tongue pains as if burnt (soon after, and second day), 4.
• General Mouth. [120.]
• Dryness of the mouth, 39 ; without thirst (after four hours), 3.
• Tension in the posterior portion of the mouth and especially of the palate, which constantly obliges spitting of saliva, 6.
• Saliva.
• Accumulation of saliva (after a quarter of an hour), 9.
• Greater secretion, of saliva than usual in the mouth, 1.
• Saliva, increased, acid (after one hour), 1.
• Taste.
• Flat taste (from 10 to 15 grains of Parisian Lactucarium), 17.
• Bitter taste (after a quarter of an hour), 5.
• Bread and butter leave a bitter taste in the mouth (after three-quarters of an hour), 1.

THROAT

• Tenacious mucus accumulates in the throat, in the morning (first days), 1.
• Slight burning in the throat (soon after taking), 15 ; towards evening (first day), 4. [130.]
• An unpleasant feeling in the throat, as if the part had been exposed to too great heat of the stove (after six days), 3.
• Rawness in the throat, after lecturing (after twelve hours), 9.
• Some rawness and scraping in the throat (after one hour), 15 ; and in the afternoon (first day), 1.
• Mucus accumulates in the fauces (after one hour), 9.
• Swallowing is difficult, with a feeling of burning and rawness on the uvula, 4.
• Swallowing is difficult, not as from an obstruction in the pharynx, or from a constriction, but because the pharyngeal muscles refuse to act (after a quarter of an hour), 9.
• Sticking-drawing pain, extending from the right submaxillary gland to the tongue and ear (after three hours), 8.

STOMACH

• Appetite.
• It caused appetite, 25.
• Increased appetite (fifth day), 3 ; at noon, 10.
• Appetite and loss of thirst (third day), 6. [140.]
• Diminished appetite at noon (second day), 2.
• Loss of appetite (from 10 to 15 grains of Parisian Lactucarium), 17.
• No appetite, 12.
• No appetite at noon, eating is repugnant to her (first day), 11.
• Appetite for bread and meat fails (third day), 6.
• Thirst.
• Increased thirst (first day), 17.
• Much thirst the whole day, beginning in the morning after rising (fifth day), 3.
• Eructation.
• Eructations, 5, 39.
• Frequent eructations (first day), 1 ; during the day, 11.
• Frequent eructations (tasting somewhat of the bitterness ot the extract), lasting only a short time, 7. [150.]
• Frequent eructations, at first without relief, afterwards with relief of the tightness of the chest (soon after, and frequently during the day), 14.
• Slight eructations, 25.
• Frequent eructations of air (after one hour), 7 ; (first day), 12.
• Frequent disagreeable eructations, which cause a transient feeling of coldness along the œsophagus, and leave a long-lasting bitter taste (first day, and soon after taking), 1.
• Acrid eructations several times during the afternoon, 1.
• Acid, acrid eructations (after half an hour), 1.
• Nausea and Vomiting.
• Nausea, 18 ; (2 scruples of Lactucarium), 27 ; soon, 4 ; (after a quarter of an hour), 5.
• Nausea and eructations (soon), 38.
• Nausea and vomiting (from large doses of Lactucarium), .

ABDOMEN

• Hypochondria.
• The hepatic region is swollen; external pressure causes tensive pain (second day), 3.
• Liver swollen hard, so that it cannot remain under the short ribs, with slight pressive pain (third and fourth days), 3.
• Pinching in the left hypochondrium, for several hours in succession, especially during rest, 8.
• A dull pressure in the right hypochondrium, in the evening (first day), 15.
• A sudden stitch through the right hypochondrium, after eating, 8. [190.]
• Several dull stitches and a feeling of heaviness in the right hypochondrium (first day), 14.
• Sharp stitches in the right hypochondrium, extending to the back, which leave behind a dull sensation (after half an hour), 1.
• Some dull jerks in the hypochondria, especially in the right (first day, 1.
• Dull jerks and stitches in the right hypochondrium, seldom in the left (first day), 1.
• Burrowing pain in the hepatic region (after eleven hours), 3.
• Periodic drawing in the hepatic region (after five days), 1.
• Pressive pain in the hepatic region (after two hours), 3.
• Bruised feeling in the hepatic region, in the morning (fourth day), 1.
• A violent stitch shoots through the region of the spleen several times (fifth day), 1.
• Umbilical.
• Periodic griping above the umbilicus; worse when the legs are crossed (first, second, and third days), 1. [200.]
• Sensitiveness of the umbilical region (soon), 38.
• General Abdomen.
• Distension of the abdomen (soon), 38.
• Diminished peristaltic action of the bowels, 38.
• Some rumbling in the abdomen (soon), 1.
• Rumbling in the abdomen, chiefly in the umbilical region (after one hour), 3.
• Rumbling in the abdomen during dinner (first day), 1.
• Rumbling in the abdomen after dinner, and some dull stitches in the præcordial region (first day), 14.

RECTUM AND ANUS

• Several hæmorrhoidal tumors about the anus, with a sensation of twinging in the rectum; after the discharge of a hard stool there always follows a somewhat thinner stool; lasting eight days. [from 5 drops taken three days in succession by a man suffering from complete amaurosis for three years, but otherwise healthy.]
• Transient drawing in the anus (first day), 1.
• Pressing in the anus, after a soft stool, 1. [230.]
• Some prickling in the anus, towards evening (first day), 4.
• Desire for stool, which however does not take place (first day), 12.
• Stool preceded by urging and griping (after two hours and a half), 1.

STOOL

• Diarrhœa.
• Evacuations of the bowels are rather promoted than retarded, 30.
• Diarrhœa, 18, 28.
• Sometimes diarrhœa (from Parisian Lactucarium), 17.
• (The customary obstructio alvi was lessened), 2.
• The evacuations of the bowels become smaller (mushy), and take place more frequently than usual; two to three times in twenty-four hours, 1.
• It causes easy stools, 29.
• Easy stool, though no diarrhœa, 32. [240.]
• Two soft stools (first day), 15.
• Two pasty evacuations, contrary to habit, during the first twenty-four hours), 14.
• It obliges him to go to stool, with a feeling of great weakness; only a little is passed with difficulty (after two hours and a half), 1.
• Stool with a feeling of general weakness and weariness, so that he was unable to sleep; yawning and accumulation of water in the mouth (after half an hour and one hour), 1.
• Frequent urging to stool, followed by stool with hard pressing, and succeeded by bruised pain in the anus (sixth day), 1.
• Stool hard (after twenty-four hours), 8.
• Stool at the usual time, but hard; for several days, 6.
• Stool hard and dry, only resulting after long pressing (three to six days), 4.
• Constipation.
• Sometimes causes constipation (Parisian Lactucarium), 17.
• Constipation for two days, followed by a very hard and lumpy stool, with burning in anus (fourth day), 3. [250.]
• Stool scanty and dry, 38.
• Insufficient stool (second day), 1.
• Delayed, hard stool (second and third days), 1.
• Stool more seldom, and harder than usual, 7.
• Stool, which usually occurs regularly in the morning, occurs twelve hours later, and is harder than usual (second day), 15.
• Stool omitted (first day), 13.
• Stool entirely wanting (fourth day), and only follows after forty-eight hours; is hard and passed with pressure, .

URINARY ORGANS

• Bladder.
• The increased amount of urine that has collected presses and drags upon the bladder, during the morning hours (first to fourth day), 1.
• Twinging pressing sensation in the region of the bladder (second day), 1.
• Urethra.
• A constant sensation while sitting still as though a drop were flowing through the urethra (the whole second forenoon), 6. [260.]
• Slight burning in the urethra, especially in the orifice (first and second days), 1.
• Urging to urinate, with periodic drawing in the glans penis, which shoots through the whole body (after eight hours), 1.
• It increases the discharge of urine, 29, 41.
• Is obliged to urinate more than usual, 8.
• Very frequent discharge of urine clear as water (first and second days, 4.
• Urine.
• Urine increased and more frequently voided, 10.
• Urine increased during the first twenty-four hours, 7.
• Urine increased in quantity and more frequently voided; she is even obliged to rise at night on account of it, contrary to habit, 14, 15.
• Increased secretion of urine (first day), 1.
• Secretion of urine increased without being obliged to pass urine more frequently than usual (fifth and sixth days), 1. [270.]
• Copious secretion of urine, 32.
• More frequent and profuse discharge of clear urine (after six to twenty hours), 1.
• It increases the diuresis, 30.
• Increased diuresis , lasting several days (after several hours), 5.
• Diminished secretion of urine, 41.
• Urine yellowish, clear, smelling of violets, 5.
• Urine brown, hot, and causing burning in the urethra (second day), 6.

SEXUAL ORGANS

• Male.
• Persistent swelling of the lymphatic vessels of the penis after erections in the morning (second day), 9.
• Painful erections during the morning sleep (first day), 1.
• Dull drawing at the root of the penis (second and third days), 1. [280.]
• Sharp drawing in the right spermatic cord and down the inner side of the leg (second day), 4.
• Desire for coition seems increased, 1.
• (It removes lasciviousness and voluptuous dreams), 25 . (From the seeds of Lactuca, in wine.)
• Emission (third night), 1.
• Emissions twice during sound sleep, without his knowledge (first night), 1.
• Female.
• It promotes menstruation, 24, 31.
• Menstruation six days too early, 13.
• Menstruation occurs four days too early, with some cramplike pain in the abdomen, 15.

RESPIRATORY ORGANS

• Larynx and Trachea.
• Feeling of dryness and scraping in the larynx and upper part of the chest, 7.
• Feeling of scraping disappears, while the feeling of fulness in the trachea continues, 7. [290.]
• On bending the body backward, the fulness in the trachea is somewhat relieved, 7.
• Rawness in the larynx (after one hour), 9.
• Rawness in the trachea obliging deep breathing (after one hour), 7.
• Voice.
• Greatly increased register of the voice (after twelve hours), 9.
• Hoarseness, 39.
• Hoarse and raw in the throat in the morning (second day), 5.
• Hoarseness in the evening (first and second days), 5.
• Cough and Expectoration.
• Some cough, with a dry, burning sensation in the throat (fifth day), 3.
• Periodic cough in short paroxysms, shaking the abdomen (first and second days), 15.
• Frequent cough (second day), 4. [300.]
• Tickling in the throat provoking frequent cough (second day), 1.
• Tickling in the throat provoking frequent cough, with a feeling of constriction over the whole chest (first and second days), 14.
• *Incessant spasmodic cough, which threatens to burst the chest; it is always caused by a peculiar tickling in the fauces, which in turn seems to be produced by a sensation of suffocation in the throat (third to eighth day), (and lasting still longer at times), 6.
• It provokes a hacking cough at times (soon), 7.
• (The cough, which before the proving had been easy and loose, changed to a dry, barking, painful cough), (second day), 4.
• Some dry cough now and then (first two days), 11.
• Dry cough in short paroxysms, with shaking of the chest and occiput (after one hour), 9.*
• Hollow, dry, spasmodic cough in the forenoon (third day), 6.

CHEST

• Feeling of heaviness of the chest, in the evening, with a feeling of filling of the air passages (after twelve hours), 7.
• Pain in the left chest, aggravated by the short hacking cough; the same sensation in the right half of the chest was also caused by coughing (after three hours), 7.
• Sensation after waking, in the lower anterior portion of the thorax, especially the left side, like that felt in the muscles after physical exertion (second day), 7.
• The whole chest is full, painful, as if beaten, with slight trembling in it (after one hour), 1. [330.]
• The feeling of fulness in the chest increases towards evening (first day), 3.
• Feeling of anxious fulness in the chest (after four hours), 3.
• Feeling of tightness in the chest, which is felt about the heart, in the afternoon (first day), 10.
• Feeling as though the thorax were too tight and constricted (fourth day), 3.
• Wakes from sleep several times at night on account of great tightness in the chest, so that he suddenly rises up anxious, and in the morning is very tired (first night), 1.
• A sensation of orgasm in the chest suddenly causes a transient tightness, with subsequent spasmodic pain in the chest externally (first day), 1.
• Readily attacked by orgasm and tightness of the chest after moderate exertion, 1.
• She feared to take a deep breath on account of tightness in the lower portion of the chest; there was then felt a slight shock (after two hours and a half), 8.
• Frequent alternations of tightness in the chest, heaviness on the chest and need of deep breathing, yawning and stretching relieved for the moment, 1.
• He is sometimes awakened from sleep at night on account of great tightness of the chest, so that he suddenly starts up anxiously (first night), 1. [340.]
• Constrictive sensation, with a feeling of heaviness low down in the chest, oppression and increased warmth, periodically increasing and decreasing, lasting through the day (after one hour), 1.
• The thorax seems constricted; on deep breathing he is unable to expand it completely (after ten hours, lasting till eighth day), 6.
• Feeling as if the region of the short ribs, especially the right side, were spasmodically constricted (after eight hours, lasting till fourth day), .

PULSE

• Pulsations 81 (before taking), 88 (after taking), 80 (next morning), (average of all cases), 41.
• Rather frequent pulse (half an hour after 1 drachm of Lactucarium), 37.
• Pulse not remarkably changed, perhaps a few beats slower than usual, 1.
• Pulse retarded, 30.
• Pulse slower (from 10 to 15 grains of Parisian Lactucarium), 17.
• Pulse slow and tense (after twenty-four hours), 3.
• Pulse a few beats slower than usual (first day), 1, 15.
• Depression of the pulse from 75 to 62 within an hour and a half, 39.
• Pulse diminished (from 6 to 8 grains of Parisian Lactucarium taken at intervals of three or four hours during the day), 17. [390.]
• Pulse reduced from 67 to 60; in some persons the pulse was reduced from 10 to 12 beats, and in one individual still more, 34.

NECK AND BACK

• Neck.
• Pain in the nape of the neck when coughing (after seven hours), 8.
• Tension in the cervical muscles of both sides (after twenty minutes), 1.
• Tensive cramplike pain in the muscles of the neck in the right side (after half an hour), 1.
• Drawing and tension in the nape of the neck, shoulders, and cervical muscles (first and second days), 1.
• Back.
• Pain in the spine, extending into the cauda equina, and also streaming through the coccyx (after two hours), 9.
• Pinching pain, periodically extending through the back, in various directions, 1.
• Drawing, frequently extending from the small of the back to the groin towards evening (first day), 15.
• Bruised pain in the lumbar region (after ten hours to fourth day), 6.

EXTREMITIES IN GENERAL

• Heaviness ot the limbs (first day), 11. [400.]
• Limbs tremulous and weak (first day), 1.
• Great weakness of the limbs, and disinclination to work, in the morning after rising, for fourteen days, 4.
• The limbs frequently fall asleep (first and second day), 11.
• Pain in the limbs, 18.
• Cramplike pains, here and there (elbows, hands, fingers, lower legs), which impede the function of the limbs; they do not last long, and soon reappear in other places, 8.
• All the limbs feel bruised, obliging lying in bed the whole day (fourth day), 6.

SUPERIOR EXTREMITIES

• Drawing in the arms, especially starting from the elbow-joints, 1.
• Frequent drawing and jerking in the arms (soon), 15.
• Periodic drawing and jerking in the arms (soon), 15.
• Fine stitch beneath the right arm (soon), 4.
• Shoulder. [410.]
• Transient paralytic feeling in left shoulder-joint (second day), 4.
• Pains in the shoulders and limbs (from 10 to 15 grains of Parisian Lactucarium), 17.
• Sticking in the right axilla, as from a small sharp instrument, lasting several days; the pain is aggravated by pressure and by raising the arm, 4.
• Wandering-tearing pain as if in the bones in the joints of the right shoulder and elbow, in the open air; it afterwards extends, now into the wrist, now into the knees, now into the leg, now into the ankle, neck, temples, etc., for a short time, lasting till the eighth day (after eight hours), 6.
• Arm.
• Dull, very transient pain in the deltoid and pectoral muscles, afterwards extending to the shoulders, during rest, 7.
• Cramplike pain on the back of the lower portion of the upper arm, which is relieved by moving it (first and second days), 8.
• Dull drawing and feeling of weakness in the left upper arm (first day), 1.
• Pain as from a sprain in the deltoid muscle of the left arm, only while the forearm is bent (after eighteen hours), 6.
• Elbow.
• Dull drawing in the tip of the right elbow (soon), 1.
• Forearm.
• Tearing pain in the right forearm, with a subsequent paralyzed feeling in the little finger (after two hours), 1.
• Wrist. [420.]
• Drawing pain in the external condyle of the left wrist (after one hour and a half), 1.
• Hand.
• Trembling of the hands, 18.
• Painful jerkings in the hands, 1.
• Cramplike drawing in the left hand (first day), .

INFERIOR EXTREMITIES

• Objective.
• Gait unsteady; he reels to and fro (soon), 1.
• Staggering while walking (from 10 to 15 grains of Parisian Lactucarium, 17 ; on attempting to walk, 18.
• Great weariness of the limbs and right arm (after half an hour), 5.
• Subjective.
• The limb falls asleep while sitting (first day), 6. [430.]
• Heaviness of the limbs and tension in the hollows of the knees, while walking, 1.
• Drawing in the limbs and back (first day), 15.
• Painful whizzing in the limbs, in the afternoon, while sitting quietly, 1.
• Thigh.
• Jerking in the left thigh (after half an hour, and three hours), 1.
• Knee.
• Tension in the hollows of the knees on rising from a seat; the thighs feel bruised (after eight hours), 1.
• Leg.
• Trembling of the left lower leg, in the afternoon (second day), 6.
• Feeling of heaviness like a stoppage of blood in the lower legs, while sitting (first day), 14.
• Cramp in the left calf while walking, lasting about a quarter of an hour (after nine hours), 6.
• Drawing and a feeling of stoppage in the right lower leg, especially during rest, 1.
• Dull drawing pain with a feeling of stiffness in the right lower leg, at times extending up into the hip, 1.
• Foot. [440.]
• A pain in the ball of the foot on the digital border of the second metatarsal bone, and in the great toe of the left foot; the toes feel grown together and drawn back, only when stepping upon them (fifth to eighth days), 6.
• Pain in the sole of the left foot as from a stone-bruise, during rest, disappearing when stepping upon it, 8.
• Toes.
• Sensation beneath the nail of the fourth toe as if suppurating, without any external alteration; and pain on pressure (third day), .

GENERALITIES

• Objective.
• It causes good nutrition, and diminishes corpulency, 26.
• Alarming convulsions in a lying-in woman (from the juice of the ordinary salad), 16.
• Weariness for twelve hours), 5.
• Weary and sleepy, contrary to habit (first day), 15.
• He is as weary and sick after a slight exertion in the house, as if he had taken a long walk, in the forenoon (first day), 1.
• Great weariness and sleepiness throughout the day (first day), 14.
• Astonishing weariness (after one hour), 12. [450.]
• Great weakness (from 10 to 15 grains of Parisian Lactucarium), 17.
• Great weakness, immobility and general exhaustion, 18.
• General Exhaustion (from 10 to 15 grains of Parisian Lactucarium), 17.
• Subjective.
• (A truly enlivening, invigorating power, from Lactucarium, in a hysterical woman), 18.
• Increased feeling of lightness (from 6 to 8 grains of Parisian Lactucarium), 17.
• Unusual lightness of the body in the open air (after some hours), 1.
• Great lightness in the open air, and an agreeable, healthy feeling in the whole body (after twelve hours), 1.
• A peculiar indescribable sensation of lightness in the whole body without narcotic effect and without any abnormality of the pulse (from 3 to 5 grains of Parisian Lactucarium), 17.
• Feeling as if the body were swimming, in bed (soon), 1.
• Periodic drawing in various parts of the body (first and second days), 1. [460.]
• Sharp, cramplike, jerking pain becomes firmly seated close to those parts of the body which bend (the neck, hypochondria, elbows, hips), and especially occurs in the evening and during rest; it is not in the joints, but only near them, and seems to prefer the extensor rather than the flexor surface, and also to be worse in the morning, 8.
• Desire for the open air, 5.
• She recovers in the open air; especially the chest becomes freer, 13.
• Inclination to sit upright, 9.

SKIN

• Inflammation and slight eruption caused on delicate parts of the skin by the external application of the extract, 35, 36.
• Fine sticking twinging and biting, here and there beneath the skin, suddenly, 8.
• Slight pain under the skin, here and there, in the limbs, almost like a fine sticking, 8.
• Prickling pain beneath the skin of the nape of the neck, which gradually becomes seated in a small spot beneath the right scapula, 4.
• Crawling itching on the left toes, and left fingers (third day), 5.

SLEEP AND DREAMS

• Sleepiness.
• Yawning and stretching of the limbs (from 10 to 15 grains of Parisian Lactucarium), 17. [470.]
• Frequent yawning, 5 ; (first day), 12.
• It promotes sleep, 26.
• Hypnotic effect, 41.
• Inclination to sleep, 39.
• Inclination to sleep, which, however, does not follow, 17.
• Great sleepiness (after a quarter of an hour), 22.
• Great sleepiness, without being able to completely overcome his previous wakefulness (half an hour after 10 grains of Lactucarium), 37.
• Great sleepiness, with frequent yawning (after two hours), 11 ; (first day), 1.
• Is obliged to go to bed earlier than usual, on account of great sleepiness, 14.
• Irresistible sleepiness (from 2 scruples of Lactucarium), 27. [480.]
• Overpowering sleepiness, with nausea (from 2 scruples of Lactucarium), 37.
• It causes sleep (when put into a foot bath), 33.
• She falls asleep while at work, in the afternoon (first day), 13.
• Quiet sleep (in a hysterical woman), 18.
• Quiet sleep, in one suffering from chronic wakefulness (from 5 to 8 grains of Parisian Lactucarium, taken in the evening), 17.
• Quiet and refreshing sleep, when taken in the evening (from 6 to 8 grains of Parisian Lactucarium, 17.
• Quiet, natural, and refreshing sleep, with diminished warmth (from moderate doses of Lactucarium), 32.
• Quiet and gentle sleep at night, but little sleep in the morning, contrary to habit (first day), 1.
• Very good sleep at night (first night), 6.
• Sleep at night sound and without dreams, 4. [490.]
• Sound sleep full of dreams (first night), 1.
• Sound sleep, with emission of semen without any sensation of it (first night), 1.
• Deep sleep, lasting five hours and a half (half an hour after 1 drachm of Lactucarium), 37.

FEVER

• Chilliness.
• The temperature of the axilla was reduced from 1 to 1 1/2 Cent., by the use of lettuce, 34.
• Chilliness in a warm room (after one hour), 11.
• Chilliness in a warm room; the hands and feet are cold, with cold creeping over the head and back (after one hour), 1.
• She easily becomes chilly during the day (first day), 15.
• An unusual sensation, allied to coldness, but not unpleasant, 34.
• Slight shivering (after a quarter of an hour), 5. [520.]
• Diminished temperature of the hands, 39.
• Coldness extending over the head and back, alternating with heat in the face, in the forenoon (first day), 1.
• Feeling of coldness in the chest (from 10 to 15 grains of Parisian Lactucarium), 17.
• Frequent coldness creeps over the back and head (first hours), 1, 13.
• Cold feet (after two and three days), 1.
• Shivering as if creeping under the hairs, 4.
• Heat.
• Temperature 29.9° C. (before taking); 30° (after taking), 29.9° (next morning); (average of all cases), 41.
• Sensation of heat, intolerably dry, especially on the lower legs, coincident with aching like that after excessive exertion in walking; from 3 to 6 A.M. (third day), 6.
• Fever; very decided headache; even the scalp is painful to touch, increased by tearing, which also affects the joints of the limbs, nape of the neck, and face; towards evening the head became so heavy that she was obliged to incline it forward; unusually dry, extremely distressing heat in the head and upper part of the body, with icy coldness of the feet, burning and lachrymation of the eyes; incessant, dry, hollow, spasmodic cough, recurring periodically, increasing to threatened suffocation, violently shaking the chest and head, together with spasmodic and painful constriction of the abdominal muscles, and region of the short ribs; at noon (third day), 6.
• Heat in the face, with a feeling of swelling and trembling of the lips, several minutes after taking.
• Sweat. [530.]
• Sweat, during the night, .

CONDITIONS

• Aggravation.
• ( Morning ), Mucus in throat; after rising, pain in chest; pressure on both sides of chest; after rising, weakness of limbs, etc.; pressure on both sides of chest; after rising, weakness of limbs, etc.
• ( Afternoon ), Headache; towards evening, feeling in chest.
• ( Evening ), After lying down, dyspnœa, etc.
• ( In open air ), Pain in shoulder, etc.
• ( Walking in open air ), Pressure in upper chest; feeling in chest.
• ( After eating ), Stitch through hypochondrium.
• ( Rest ), Pain in deltoid muscle; drawing, etc., in lower leg; pain in left sole.
• ( Standing ), Feeling of weight upon abdomen.
• ( Warm room ), Vertigo, etc.; pain in forehead.
• ( Writing ), Burning in lids.
• Amelioration.
• ( In open air ), General relief, 1 ; especially of chest, 13.
• ( In bed ), Ill-humor.
• ( Sitting erect ), Chest symptoms.

SUPPLEMENT: LACTUCA. Authority.

43 , Dr. Fischer, in Rust's Mag., Lond. Med. Gaz., 1839-40, vol. i, p. 862 (Am. Obs., 1876, p. 80), general effects.

• It quiets without previously exciting, and produces sleep without insensibility, lessens the action of the heart, and produces a general tranquillity throughout the whole constitution. In large doses it causes delirium without stimulating, diminution of nervous power, disturbance of the digestive functions without vomiting, 43.