Natrium muriaticum

Volume III — Main text

NATRUM CHLORATUM.

The " Liquor Sodce Chlorats '* of the British Phannacopoeia, Labarraque*! solution (of chlorinated Koda).

I. /Vrw'w/. — I. Cooper. Parhogenetic effect* observfd in persons taking the drug. — Very low-spirited and depressed, could cry all d. Rapid emaciation (in a girl of t«'enty-one). Aching in c'ery llimb and feeling as if bereft of all power, and as though she would faint upon slightest moTemcnt. She becomes quite overpowered (from } dr. 3 times a d. in woman of 65). Vertigo caduca, — a very constant and characteristic symptom along with aching across forcheatl. Momentary indescribable sensation all over head. Swimming reeling, as though top of cranium wcT« about to float off, worse when looking upwards. Pain across foretiead, extend, ing down nose and up o?cr entire head, witn great tenderness of scalp, and a thumping noise in eai^, which is worse by lying on either side ; has to place tack of her head agaimrt the pillow in order to gain sleep. Pain in r. side of head, going from behind mastoid process to upper part ot orbit •* across the eye i" causes eye to feel stiff and weak ; aggravated by having slept, but continuing by d, as well as by n. Pain darting from one temple to the other, coming and going with equal suddenness. In a woman, aged 51, great depression, and freling in head as though cranial bones were being crossed one over the other, and as if she mu4t fall forward, a «irt of silly feeling , vrith a nasty ta^te, just m she used to have after taking iodide of potassium, but without the iodine cor)'za. Paralysed feeling of her brain, with similar sen&ation in all limbs, and numbness of tips ot fingers, and recurrent faintings. Throbbing headache in 1. temple, coming on immediately after her midday meal, and going off after tea. Much pain across small of her back, worse on getting up in m., existing along with want of appetite for breakfast, but fiiir appetite for supper. Pain in both htp-jointf and in calves, with tingling extending to loes. Both hands are swollen every m. {observed in vcascs). Extreme weakness in her ankles and knees. Pain under r. ear when swallowing, with much pain, tenderness, and swelling up side of head, followed by a most painful gathering, which bunt and diM-'harged strongly. Sore, irritable spots form in throat and along both sides of tongue. His teeth become brittle. Sores, angry looking and moist, break out about mouth. Sore pimples come on in-tidc of lowcrfip,at tiic commencement of a cold. Sores on inside of her cheeks, which began on I. side, and gradually spread over mouth, with nasal discharge and influenza. His throat invariably becomes fiore (observed in several rases). Neuralgit pain in I. side of face, from lower jaw, extending to upper, and across eyes and nose to forehead, comingon irregularly and lasting from i to i^ h. (produced after taking the drug for 4 d.). Sore-throat, with diflicult deglutition ; a flat ulcer torm» on tongue far back to rtmt after taking drug for a week, ai\d goes away immediately it is discontinued. Swelling upon r. upper jaw, close upon gum (gumboil), very painful to touch. The throat becomes red and sore (in a man aged si, whose health was quite good cxtTpt for a nasal polypus). Swelling, affecting upper and lower jaw of 1. side, with swelling on inside of the jaw between gum and tongue, throbbing in part and shooting pain extending up to temples and down 1. side of neck, relieved by cold applications, mcreased by worry, not interfering with appetite. Tongue is furred in m., and there is constant putrid taste throughout d. The tongue is white and shrivelled at sides, and there b taste as if she had been sucking alum ; appetite for meat fell off. Epistaxis j blood comes away both by n. and d, in clots, and is dark coloured (in a prcgnaut tvoman). Cough, with white tasteless phlegm and tightness across chest a> from a weight, which keeps her from sleeping, and constricted feeling on inspiration at pit of chest (along with general feeling of weakness following a miscarriage). Cough distressing, with a little phlegm, continual during d. (in a woman aet. 35). Pain under heart, with catching inspiration. Pain across upper pan of chest, off and on, and pain with fulness across hypochondria, with pains extending down from both sides of waist to womb, causinga phleg^ny discharge. Pain under T. axilla and I. mamma, aggravated by lying down, with sickish giddy feeling ; when walking about, is obliged to keep sitting down. In a delicate anemic woman suffering from uterine weakness, the N.chl. caused a pain toappeirin 1. infra-mammary region, which affected 1. side of chest, shouldere, and top of head ^ shoulders became

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stiff 2nd painful, and top of her bead and tide felt tender to touch, and ached, an un bearable pain j telt drowklnets after meab; I. hand much swollen one m. ifrcr waking, and next m. r. wu limilarly affected i bowels became confined and lets urioe was voided. She U unable to Mt down without falling asleep, her appetite 6UUoff, but boweU are rerular and tongue clean. In a girl, rt. ii, aching pain in 1. side at waist, preventing her from sitting upright. Swelling low down io abdomen,

foing up to lier chest, and cau^iing dyspncca, worse after eating, with a good deal of atus. A weight f.etmr. to fall from across pit of her cbeM to pir of aMomen, and an aching, dull sensation, indescribable, but different trom an ordinary headache, occurs on top of head after each dose and lasts for | h. Nausea and sick feeling ; she becomes drow«y during d. and wakeful at n. Loss of appnJte for breaktsjt, but fiji appetite for supper. When taken while the patient is recumbent, the N. chl. gave rise to a feeling of sickness. In a decidedly consumptive girl, M. 16, its continued use made her feel drowsy and lazy, as if she could lie in bed all d., ami her tkin became covered with pimples that smarted after washing, and upon going into open air i the slightc«t drop of^cold water as a drink irritates these pimples. Oinfinemeni of bowels for ) d., and then passage of large, hard, offensive motion (in a ^rl of it). Great exhaustion as if about to die before bowels act j sudden and forcible expulsion, with consequent complete relief. In a woman, ict. 4.1, cutting pain like knives in the anus, which comes on every e, between 6 and 7, and goes away during n., but not at any stated h. In a little girl, zt. 3, scalding when urinating, with soreness, itching, and smarting of vagina. Violent metrorrhagia. The monthly period comes on at once, a week before its time (in a perfectly healthy woman, after taking a dose of 1 dr. in water). In a woman suffering from prolapsus from injury, xt a5, it bnmicht on frightful vaginal pruritus, just inside lips of vagina, getting better and worse, and obliging her to tear her^lf to pieces. Uterine bearing down, severe backache and head, ache, anecring temples and back of head, making her feel light-headed and sickish, generally worse at n. She cannot take the N. chl., as it causes feeling of opening and shutting in womb (in a healthy woman, rt. 65). The monthly period delays a week over time, aod during ist d. she has more than usual aching in the back (in a £urly healthy glH, act. ai). Great sexual excitement after each doK in a man, act. «5, of impre$^ionable temperament. Almost unconquerable sexual desire after each doie, with priapism. Heavy sleep, with much disinclination to get out of bed in m. Drowsy during davtiroe, wakeful at n. Drowsiness after meals. The child when a^eep has a ghastly look as if dead ; his sleep is quiet. Much distressed, laughs, cries, and talks in her sleep; keeps her hu&band awake. Small gatherings form on fingers of both her hands. Pimply rash appears on the face, which is very irritable, especially at n. In a woman, xt. 31, from a drop, diluted, red smarting rash oo face and neck, worse after meals or after warm drinks ; a uniform redness with tendency to blister, " as if from a mustard plaster." Its painful part* feel hoc {Brit, J«mrm. i/" Hom.f XXXV, 340.)

NATRUM MURIATICUM.

6odic chloride, NaG. Common salt purified by solution in distilled water and

recrystallization,

I. Provings, — . Hahnemann, CArMjV/>iWf«j, part iv of original, vol. of translation. Contains 1349 symptoms from self and 6 associates.

fl. (Austrian provings, made with Hahnemann's preparation, as above.) Dr. Arneth showed an almost absolute un impressionability to the action of common salt. He proved first, for three weeks, the dilutions from the 30th to the ist (from ij to 2 tablespoonfiils each time) ; and took afterwards of the raw materiaJ from lo, 20, 30 gr. to I oz., the latter every d. at l\ a.m., in a glass of water. Beyond an unendurable salt taste and inclination to vomit after the large doses

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he noticed during the time of the proving no action ; yet for almost fix weclcs after he had taken the last dose his stools were hard, and for several d. after be had no evacuation at all. {Oest. Ztitsch.f. Hom.^ iv).

1. Dr. BoHM merely tried the 1st trit, (5 to 95). In spite of this his proving furnishes several characteristic salt symptoms. He took the remedy each time dissolved in more or less water. On taking, Nov. 5th, 5 gr., he experienced soon after pressing in temples, and for an h. copious flow of saliva into mouth. The following d. he had littJe appetite^ firequent eructations of air, and feeling of nausea in stomach ; he was ill-disposed, and slept uneasily through the first n. On the 3rd d. he was well. Nov. 8th. — 10 gr. soon excited crucutions of air ; half of next d. salt caste of saliva, feeling of weakness, unusually frequent emission of watery urine, urging to stool, which continued for a long time, with burning in anus subsequent to a pappy stool. 10th. — 20 gr. were followed hy exactly similar phenomena. l6th, — After 50 gr., taken in e., B — became soon sleepy ; was obliged, in spite of his sleep being sounder than usual, to rise frequently to micturate, and each time passed much pale urine. At the same time there was tightness and distension of abdomen, with dryness of palate, increased thint, and frequent eructation. The urging to urinate was united sometimes with pressing in rectum. These urinary symptoms were repeated the two following n. 22nd. — logr., 8 a.m., were followed by profuse secretion of saliva, pressing in temples, frequent eructation, nausea, painful contraction in umbilical region, relieved by emission of flatus ; little appetite at dinner, after dinner sleepiness, frequent urging to urinate with only scanty emission of urine j at n. frequent erections with emission of an adhesive fluid, uneasy sleep, many dreams (lascivious or of ghosts). Next m. prover was weak, dejected, illhumoured. No stool for 2 d., very unusual with him. The same phenomena appeared after doses of 100 gr. on Nov. 27th and Dec. 5th and 7th. The pappy evacuations which now followed brought relief to the abdominal symptoms and quieter nights. 130 gr., Dec. 10th, e., created pressing pain in forehead (for j h.) ; after two stools colic, violent yet ineffectual urging to stool^ pinching in umbilical region at n., in m. two fluid stools with burning in anus ; this and following d. morose humour, total loss of appetite, prostration in limbs, continual dampness of orifice of urethra, with drawing in spermatic cords. After 150 ^•> which B — took in m. of 12th, an h. before breakfast, he was first seized with transient drawing pain in both sides of the inferior maxilla, \ h. later pinching in umbilical region with urging to stool without any result. Breakfast was not relished, in forenoon frequent empty eructations, with feeling of discomfort in stomach. After dinner a pappy evacuation of an orange-yellow colour. In e. indisposition to mental occupation. Sleep extremely restless, not refreshing, interrupted by many vivid unpleasant dreams. In m. on waking, feeling of weariness and prostration. These phenomena showed themselves, only less intensely, also during the two following d. On both d., however, there was no stool ; and that which followed on the 3rd d. was hard and insufficient. (Ibid.)

2. Dr. Frolich took at first (March 14th to 3Xst, 1843] ^^^X

early in m., fitting, 3 dr. ckf the 6th dilution^ but noticed no morbid phenomena afterwards. Just as little result followed a second attempt, io which he took for 10 d, early in m., fasting, 10 gr. of i^^ trit. with water. A third attempt began with drinking, Nov. lOth, early in m., fasting, 3J dissolved in water. In afternoon, filling of fulness in hypogastriutn, livelr grumbling in 1. groin and frequent emission of flatus occurred. On ^ov. I ith he again took 5J. In the succeeding n. he had a vivid dream. On the 12th, { b. after taking a similar dose, feeling of nausea, soon passing off. In afternoon for 5 m. continued sticking corresponding exactly with spot against which apex of heart strikes (not influenced by breathing). In e. transient nausea with feeling of fulness and tension in hypogastrium. In n. vivid, connected dream. A similar dream occurred in following n. after taking in e. 5J. On 23rd, at II a.m., he took again a drachm. An h. after a moderattr dinner he was seized with very painful stitches in cardiac region lastin for some m. After a similar dose on 24th he had tn n. very lively ani connected dreams. On 25th took 51], thereupon painful sncking cardiac region coming on after continued loud speaking. 26ch aoi 27th. — No medicine and no symptoms. 28th. — Again took 51]. In e. on walking in the street^ violent stitch in cardiac region so that he stood still with fright and instinctively pressed painful spot with hand, Nov. 30th and Dec. ist, once more ^ij. The evacuations appeared during the time of the last experiment very irregularly and of varying consistence. (Ibid.)

1. Dr. Hampe communicates Co us by letter the two experiments which he made with common salt. We keep to the words of the original : — " I am 40 years old, of sanguine, choleric temperament, powerful, thickset frame, and enjoyed to my 23rd year excellent health. About this time I was attacked, in consequence of a chill, with rheumatism, which recurred ever after for many years on the most triAing occasion and in the most varied forms, once even the cause of paraJysig) of 8 d. duration, of the facial muscles of the 1. side. For 4 or 5 years I have been quite free from this, and, moreover, with the exception of an herpetic afJcction (which will be more fully described below) perfectly well. Fifteen years ago an intermittent fever, which attacked me in Banat, and accompanied by which I was obliged to travel for two months in the mountains of that region, reduced me very much, inasmuch as it frequently returned during a period of nine months.

e. '' Proving with 6 gl. doses of 6th potency. April and, 1 843, took a dose at 10 a,ro. No symptoms. 3rd. — 7 a,m., soft, copious stool and again at 8.30 another profuse and more fluid evacuation with smarting in anus. 10 a*m., a dose, which I took every subsequent d. at nearly the same h. No symptoms except a remarkable diminution of sexual desire. 12th. — A very deep and unusual sleep after dinner on a chair. In e, ticking in Lear as if from a watch for 10 m. 13th, — 6 a.m^ pain in r. car as if one were pulling something out of it with a book, for ^ h. In e. at 9.30, urging to stool with copious evacuation. 14th. — 7 a.m., copious evacuation of half-fluid fxces with smarting in anus. 15th. — 11 a.m.,pressivc nain in forehead and cveballs«so violeni I could raise the

to cease reading. After dinner pains increased to that extent that I was obliged to lie down. After 4 h. I was better, but eyes were suffused with tears. After 2 h. same phenomena returned in same way. From 4 to 7 p.m., continued slight internaJ shivering. At 8.30 p.m., I enjoyed my supper and pipe quite well. Slept through n. quietly and felt perfectly well next m. i6th to 20th. — ^Toolc nothing. 21st. — 8 a.m., took another dose. 22nd to 24th. — No symptoms, 25th, —Another dose ; no symptoms. 26th. — Painfulness and swelling of gum behind I. upper middle incisor ; sensitiveness of teeth in brushing them. 27th. — Same symptoms; stool more consistent.

d. " 28th. — One scruple of pure crystallized salt. Gum about the first affected tooth is healthy, but same condition shows itself in gum of 1. neighbouring tooth. Sensitiveness of teeth has ceased. 29th, — To-day gum of 1. eye-tooth is similarly affected. After dinner, without previous fatigue, and contrary to habit, great sleepiness, so that I again slept for an h. in the chair. 30th. — Gum of last affected tooth gapes and is painful, but at noon is again normal." [Proving was now internipted, but before its resumption in November, H — found that a prurigo papulosa of legs, of 6 to 7 years' standing, had disappeared.]

J. "Took, Nov, T2th, at ia.45 p.m., 2 scruples. 13th. — li a.m., itching on hypogastrium for 5 m. At 11.15,2 scruples. 14th. — Again 2 scruples. Usual stool in m. did not occur. At noon itching of short duration in r. calf, -J- h. later on 1. inner ankle for 10 m., then for some m. in 1. calf. At 4 p.m., after scarcely noticeable warning and with much trouble, inasmuch as rectum did not assist, a very scanty semi-consistent evacuation. 15th. — In m. usual easy stool. At II a.m. 2 scruples. i6th, — 10.30 a.m., again 2 scruples. In c, at 8 violent itching on inner surface of I. forearm near wrist for some m. As I examined it, two red herpetic spots showed themselves, of the size of a small lentil. 17th. — About 5 a.m. I was awakened by pains in abdomen, especially in stomach, with dryness and burning along oesophagus up into throat, which, however, did not prevent me from again falling asleep. When I awoke at 7 a.m. my eyes were quite gummed up; at same time sticking and pressing in 1. eye. No red* ness, however, showed itself. One of the spots which appeared in thee, had gone ; the other, examined with a lens, showed itself to be a cracked or torn vesicle, whereby the whole, examined by the unaided eye, had a rough, tetter-like appearance. At 10.30 a.m., 2 scruples. After Jh, pinching around navel. 5 p.m., sticking in r. side of chest for i h., which returned again an h. afterwards, and then lasted more than an h. 18th. — Took no med. 10 a.m., intermittent drawing from nape of neck towards occiput for i h.; cramp-like pain m r. hipjoint, which became rather troublesome in walking. The drawing in nape of neck recurred in e. at 7 for i h. 8.30 p.m., dulness of head, oppression in chest for j h. ; violent long-lasting stitch in 1. knee; fijeling as if a hair were lying lightly on inner edge of I. thumb towards wrist, from 20th onwards I took no med. The second red spot had quite disappeared by the 24th. On the 22nd I was seized with a fluid corvza, which attacked on the 24th the eyes, the throat, and the larynx, and was united with dulne&s of head and great prostration; the chest

affection of which — short dry cough with feeling of dryness and soreness «-has not yet quite disappeared. 28th. — It is remarkable that I bad given no particular occasion for the above, and that the secretion from the nose ceased without its having assumed a yellow colour and thicker consistence." {Ibid.)

1. a. Adalbert Huber. surgeon in Rcichenau, Bohemia, act. 28, sanguineo-phlegmatic temperament^ leading a simple life ; was never seriously ill ; as a child often troubled with an eruption on the head, latterly with a catarrhal affection of the throat every year, and when that omitted with inflammation of the gums \ began his proving November loth, in m., with 5J of 30X dil., after which, however, he noticed no change in his health. 7 he following d. he took 5J of 2Sth dil. The same d.^and particularly next m. in preparing a trituration, he noticed a sudden weariness of L wrist and r. arm.* After 20th dil., taken oa 13th, he was confused in his mind during whole d,, and felt pressing pain in forehead. After 15th dil. (Nov. X5th in m.) there came on in n. great heat of body, followed by sweat, especially in head. Iith dil. (m. of 17th] excited during whole d. a kind of colic, which was relieved by emission of flatus. After 8th dil, (20th) prover observed in course of d. single stitches in hepatic region, sensitiveness of liver to pressure, stitches in penis towards glans, weakness of 1. arm (felt par* ticularly in shoulder-joint) so that he was not able to lift a pound weight with the outstretched arm. Weakness of arm continued during two following d. 23rd. — 6th dil. was followed by pressure at pr;rcordia, sensitiveness of latter co contact^ painfulness of 1. arm, especially in region of deltoid muscle and shoulder-joint. On being pressed, arm pained as if bruised, and joint would not bear lease movement without pain. The phenomena disappeared gradually during 3 following d. After 4th dil. (27th) troubles occurred during urinarion. Urine was emitted in a weak stream and only during strong pressing. After a normal evacuation he got a troublesome dribbling of urine and pressing pain in rectum, as after a very hard knotty stool, so that he could not sit.

b* Dec. 1st, A. H — took 15 gr. of 3rd trit. Soon after appeared inclination to vomit, weakness in c., trembling of limbs after slightest exertion, with more frequent pulse. 2nd. — 5J of 2nd trit. caused throughout d. frequent micturition and much emission of flatus. 5] of 1st trit. on 6th had same result. The frequent micturition lasted for next 2 or 3 d. The urine looked pale and clear, yet smelt strong and tasted sweetish, roth. — A. H — tried 10 gr. of pure salt. The following n. he was troubled with frightful and anxious dreams of murder and imprisonment. On awaking he found himself bathed in profuse perspiration and felt in m. very weak. The succeeding 4 d., excepting frequent pressure above r. nipple, he noticed no symptom. Repetitions of same dose on 15th and 20th remained totally without result. {Ibid.)

1. a, A. H — further proved salt on 3 girls and a boy. A scrofu* lous girl of 7 began with 27th dil., which was reduced 3 stages each time as far as the 2nd and xst trit. Frequent sticking and burning in

• Wu this phenomenon not the natural conKqucnce of the (perhaps uoaccustomed) exertion during the operation \

forehead, tearing in canthi with darkness before eyes, and solitary stitches in hepatic region, were the few symptoms which ensued.

h. A healthy girl of 12 was seized whilst she took 30th to 20th dil. with violent vertigo as if intoxicated and stitches in region of liver. These symptoms frightened her from any ftirther attempts at proving.

£. A strumous boy of 1 2, who frequently suffered from bellyache and diarrhoea, on taking 28th dil. got bellyache again ; after 23rd dil. distension of abdomen and burning around navel; after 13th diL sticking in hepatic region lasting for 6 to 7 m.; lastly, after 3rd dil., sticking and burning in forehead, and burning, especially in fossa navicularis, during urination.

d. A girl of 19, sanguine, has menstruated three years, always healthy, took 30th down to i6th dils., but perceived nothing important. After 15th dil. she got pain in belly and giddiness. The latter recurred every moment. She was as if drunk, and during whole d. could not take a single step with certainty. The stool from that time forward was harder, rarer, and scantier. 10 gr, of 3rd trit. caused tearing in teeth up into temple, sticking in forehead (e.), pressing in stomacn, a firm dry stool like sheep dung with violent stitches in the rectum, increased emission of urine (she was obliged frequently in the n. to micturate). After 10 gr. of 2nd trit. there followed next d. cough with tickling in chest, pressing in forehead, burning coryza, sticking in middle of chest, a soft stool twice. 10 gr. of ist trit. produced on 1st d. heat in head, sticking in the forehead as if with needles, weakness of the stomach, nausea to fainting. On 2nd d. sticking in region of sternum at each respiration, shortness of breath, stitches in praecordia, worst during motion, coueh with tickling in chest. The catamenia were delayed about 5 d. During this time she felt weak and prostrate, and her feet heavy. Ulrimately the catamenia appeared, accompanied by violent pain in the hypogastric region, nausea, and inclination to vomit. (/^V.)

1. fl. Wenzel Huber, surgeon, in Klcinzell, in Upper Austria, proved salt on himself, his wife, and three children. He began his experiments on himself Nov. nth, 1843; ^^ ^^^^ ^^^ ^''"g always early In m., fasring, diluted with water. 30th to 25th dil. showed no noticeable influence. After 24th dil. (ryth) throughout whole d. there was slight pressing pain above eyebrows. 23rd and 22nd dils. (i8th and 19th) were also without result. 21st, 20th, 15th, and 14th dils., which he took 20th to 23rd, made themselves noticed by a salt taste on the lips. So soon as the moist tongue touched the lips, it was as if it had touched salt water. Nov. 24th to Dec. ist he tried a series of dils., the 13th to the 5th. The symptoms which he noticed thereupon were certainly in number but few; they, however, have distinctly the N. mur. character. The intense salt taste after the higher dils. (13th — loth) gave place in the lower ones to a clayey, insipid taste ; tongue was coated white; hard palate for some d. is as if scalded, and pains on contact ; sometimes he noticed an offensive smell from mouth ; beer tasted bitter (in spite of this appetite remained tolerably good) ; stool either entirely failed or was firmer than usual and evacuated with trouble. At same time there developed itself on edges of eyelids a

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regular catarrhal affection. They became red, burned, especially in e., when reading, and secreted mucus, which in m., on waking, gummed up eyes and formed into crusts. The 4th, 3rdj and, and 1st trits., which provcr tried on different occasions from Dec. 2nd to Jan. 4ih, commencing with jo gr. daily and increasing each dose by lo or 20 gr. as far as 100, produced only a few new symptoms \ feeling in anus as if a small rough, pointed plug stuck in it, or as if anus was full, which was followed by frequent, but ineffectual, urging to stool ; itching in scrotum, or between scrotum and thigh, obliging him to scratch j fulness and distension of stomach and bowels ; heartburn ; increased secretion of saliva ; uneasy nights full of dreams ; late in falling asleep, early awaking. The eye affection continues. During ist trit. stool was very irregular, sometimes hard, sometimes soft. Diarrhtra appeared a few times. The taste showed itself occasionally saltish again.

A. Salt in substance, in doses of lo to 40 gr., 5th to 15th Jan., did not enrich list of symptoms. Only the eye affection became worse, edges of eyelids and canthi (specially external) burned violently throughout whole d. and secreted much acrid fluid. He felt pressing pains in eyes as if they were inflamed. In reading he sees as it were through 2 fog. Was not disposed to work, especially to study. A drachm, on loth, excited, soon after taking it, nausea and burning and fulness in stomach, subsequently ofl^ensive smell from mouth, and offensive flatus, hard inefficient stool, itching in scrotum and prepuce, unquiet sleep. After I J dr. there came feeling of burning heat and fulness in stomach, nausea, and inclination to vomit with accumulation of water in mouth. Nausea recurred frequently during d. He had moreover the whole d. pain in forehead. He felt himself weak. At the thought of the saline solution a shudder ran through him, with loathing and inclination to vomit. The burning, lachrymation, and secretion of mucus in eyes increased. He was h'equcntty seized with contractive (spasmodic) pain about navel. After first dose of i^ drachms (Jan. 17th) anus was swollen ; the feeling of a plug sticking in it caused constant desire to stool ; after 2nd dose on i9tn diarrhoea came on twice. The majority of these symptoms appeared, although less intensely, throughout the subsequent 8 — xo dr. The most obstinate symptom was the affection of the eyes. In the m. he perspired generally profusely ; the sweat smelt sour. Throughout the whole duration of proving the sexual desire was remarkably diminished. (Wzl, H — is 43 years old, powerfully built, melancholic-phlegmatic temperament, txcept the usual diseases of childhood, he was never seriously ill. He led, as country surgeon, a very active life, and exposed himself at all seasons of the year to every change of weather with impunity. His mode of living is very moderate. He takes nothing but soup at breakfast. His dinner consists of soup, veal or smoked meat, and vegetables. In the e. takes soup and potatoes. He drinks neither coffee nor wine nor beer. He smokes tobacco, however, almost the whole d.) {Ibid,)

1. The wife of the last prover proved common salt during a period of more than two months from the 30th dil, to 40 gr. of the raw material. She is forty years old. Descended from healthy parents, she was attacked as a child soon after vaccination by an inflammation

I I

of the eyes which lasted for years. TTie cacamenia appeared in the sixteenth year without any trouble. In her eighteenth year she became affected with the itch. Although the latter was cured partly by internal^ partly by external remedies (especially sulphur), still the prover was not from that period perfectly healthy. Up to her twenty-fifth year, when she married, she had oozing nipples, which symptom disappeared during her first pregnancy. She recovered afterwards easily and successfully from nine pregnancies. After each confinement, however, there appeared on the back of the hand near to the roots of the fingers an herpetic eruption, which often lasted a year and a half i generally so long as until she was again pregnant. Also during the time she proved the salt it was present. Her diet is simple, without coffee, or spirituous drintcs, or seasoned dishes.

a. The 30th to 20th dilutions — a lower dilution taken each day— from Nov. nth to 21st induced no action. On Nov. 17th the cata» mcnia ought to have appieared ; they, however, remained away, most probablyinconsequenceofbecomingpregnant. 22nd. — isthdiJ. On touching the lips with the moist tongue there was a sour taste ; uneasy sleep ; frequent waking. 23rd. — 14th dil. The same phenomena ; sensitiveness of the gums to contact. During the 3 following d., in which the 13th, i2th, and loth dils. were taken, the above symptoms gradually disappeared. 25th. — The stool which otherwise regulariy occurred was absent. After 9th dil. (27tfa) the herpes was aggravated, with violent smarting and burning. After 6th and 5th dils. (Nov. 30th and Dec 1st) a salt taste developed itself on lips and palate ^ the stool was hard and insufficient. After 4th trit. (Dec. 2nd to 8th), repeated in doses of 10 and 20 gr., and after 3rd trit. (9th to 14th) in doses of 10) 20, and 30 gr., the above salt taste disappeared again ; stool harder than usual ; nights continuously more or less uneasy, she awoke frequently and fell asleep again with difficulty. Nausea was felt during n. of 6th. Of 2nd trit. she took, Dec. rsth 10, 16th and 17th 20, i8th, 19th, and 20th 40 gr. On 15th chilliness in e. j cutting pain around navel at intervals at n. ; towards m. pressure on chest, a soft scool, chilliness. On 16th during d. frequent intimations of contractive pains around navel. In n. these pains increased very much, and ceased only after a loose stool, Pains and looseness were repeated in course of n. 8 times. Chilliness even in bed and on getting up. Early in m. dulness in head and vertigo, so that she was obliged to lay hold of something. 17th. — The menses remained away for the second time. During d. chilliness, stupidity in head, heaviness and pre&sure in occiput. In n. again flying contractive pain in bowels around navel, with oppression of breathing. i£ the pain ceases, then single stitches occur from sacrum into thigh. Towards m. pressure on chest ; it is as if cavity of chest were too narrow. On j8th, chilliness throughout whole d. ; in n. pressure on chest, which towards m. became so violent that she was obliged to sit up in bed in order to be able to breathe. I9th,20th, 21st.— Continued chilliness i conjunctiva and edges of eyelids became red and burning; throughout d. frequent attacks of vertigo ; periodical pressing on chest, aggravated at n. and towards m., united with dyspncea^and compelling her to sit up; at same time constant pain in abdomen in region of

navel, of contractive kind ; sometimes stitches from sacrum into thigh ; a kind of ringworm of the size of a penny piece showed itself on thighs, belly, and arms. From Dec. land to Jan. 8th, she took ist irit. in doses rising from ]0 to 30 gr. daily. The above phenomena, which continued throughout whole time with more or less intensity, were accompanied with feeling of great weakness, early before rising, disappearing after getting up during first days of proving, but at last continuing whole d. ; swelling (knotty) of breasts, so that the least contact was painful ; tip of nose became red, hot, and painful, — subsequently there appeared on nose a group of vesicles size of a pin's head, whicK filled with transparent lymph ; at last these united and formed a scab. The ringworm increased from day to day. The breast symptoms one n. were so violent that in order to breathe she was twice obliged to rise out of bed. On last d. of proving (Jan. 8th) she had a peculiar sensation in the hip-joints ; it appeared to her in moving and turning the body as if the heads of the bones came out of the sockets.

h. Jan. 9th. — Prover began with salt in substance. She cook on this and the following d. 5, from nth to i6th 10, on 17th 20, and on 19th 40 gr. On 9th, throughout whole d., chilliness and weakness; only with trouble remained out of bed ; cutting in belly around navel ; difficult evacuation of a soft stool, she was obliged to press violently at the time ; sensitiveness of breasts ; transient attacks of palpitation of heart; difficult falling asleep j frequent dreams. loth and nth. — Same phenomena. 12th. — There was added increased secretion of mucus in genitals. 13th.— Early in m. on rising from bed spasmodic pains proceeding from navel, becoming of drawing character in sacrum, and terminating as stitches in hips and thighs. 14th. — The yellow thick scab fell from the nose without leaving any cicatrix behind. Otherwise phenomena of d. before. Mucous discharge from genitals increased up to 19th. It was white. At same time frequent tickling in anus and stitches through rectum, so that she was forced to cry out. The catamenia remained away for the third time. The herpes disappeared, and arose again in other places, most numerously between the , breasts. The spots are from size of a lentil up to that of a penny piece, and itch, particularly on becoming warm. 40 gr. produced, soon after taking, flow of water in mouth and loathing, — symptoms which were repeated next m. without medicine. At same time great weakness, which forced her to lie down. The symptoms in breasts and abdomen disappeared towards 22nd. On this and following d. she complained of coldness of feet ; little finger and ring finger, likewise whole of I. foot, were for t h. as if paralysed, gone to sleep, and numb. The discharge from the genitals gradually diminished, and by 30th had almost entirely ceased. The sexual desire was during the whole of the proving suppressed. Up to Jan. 2i8t the herpes had spread over the whole body. It had at the end of the month, at the conclusion of the report of the proving, not yet disappeared. (Ibid^

1. Wzl. H— 's three children took the dilutions, the triturations, and the raw material of common salt in the same order as himself, only each of them each time 50 dr. of the dilutions and 5 gr. of the tritura* tions and of the raw salt.

•

a. Carl, act. 9, melancholic, dark, stroDg, large-boned, plump, hardened to heat and cold, never seriously ill, was affected neither by the high nor the low dilutions ; even the raw salt, which he took sometimes exceptionally also in 10 and 20 gr. doses, produced not the slightest disturbance in his feelings.^

b. Emilie, a lively, fair-haired, blue-eyed, delicate girl of 5, always healthy, showed no indications of the action of salt from the 30th to the 13th dil. (Nov. irth to 24th). After the 12th dil. (25th) she complained of smarting and itching in different parts of the skin, which lasted till Dec. 7th, on which d. soliury herpetic patches appeared alt at once on several parts of the body. (She took from Dec. 2nd the 4th trit.) TTiese disappeared after scaling off generally by the 8th or 12th d., only to give place to others, and this continued through the whole period of the proving. On the 23rd there were thirty of them present. Jan. 9th (5 d. after she had begun to take crude salt) edges of eyelids became red, eyes in m. adhered together with scabs. This symptom continued till i6th. The ringworm totally disappeared by Feb. 3rd.

e, GusTAv, act. 4, resembling in temperament and constitution his sister, healthy with the exception of an herpetic eruption about 1. eyc,t had similar ringworm on the body to Emilie while taking the dilutions, only they were in his case much more numerous. Dec. 8th. — He received of the 4th trit., instead of the usual 5, by way of exception lOgr. He was indisposed the whole d.^ easily offended, and cried on the least provocation. 15th (2nd trit.). — He complained much of smarting and itching at anus. He was at same time very ill-humoured, and cried readily. In e. he cried out that there was a needle in anus. Examination showed a living worm (oxyuris). On the following d. there were several more live worms discovered. The smarting and itching continued till 20th, only in less degree. On Jan. 3rd he complained again of violent sticking. Another worm was found. He had up to the end of the proving frequent twitching in anus, although no more worms showed themselves. None were found in the stools during the whole time. The ringworm had not completely disappeared 4 weeks after. (Ihid,)

II. Dr. WiLHELM HuBBR began Nov. 5th, 1843, with the 30th dec. dil. He proved on two consecutive occasions (the second time reducing by fives] the whole of the dilutions down to the first, and then began with the raw material itself; and after he had repeatedly

• Six weeks after the termination of the proving Carl showed ringwonn over the whole body, so that he appeared to his relations just as if he were pickled.— WzL. H.

t This eruption had appeared on the boy a year before. The skin round about the eye was red. On ihts basis appeared many .small, somewhat pointed vesicles. These filled at first with a transparent, thin, yellow fluid, burst or were scratched, and formed on drying scurfy scabs. After falling off the skin below showed new vesicles. By>and>by the skin commenced in the middle of the eruption to crack ; from out of the cracks water oozed, which thickened into scurfy scabs. The lower eyelid was swollen, its conjunctiva slightly reddened. The eniption disappeared after the use of feveral doses of sulphur in the coup<e of six months, but four weeks prior to the commencement of the proving again appearetl. G. remained unchanged during the whole of the proving, only towards the end of it he appeared to diminish somewhat in bulk.— WzL. H.

VOL. lU,

as

tried the latter up to half an ounce a d., be terininated hts proving Jan. 19th, 1844.

a. The first 10 d. trial, during which W. H— took the 30th, 29th, he, according to their order, as far a» the 14th dil. daily^ once or twice in m., or m. and c., produced either none at all or very few symptoms, viz. : — "• Frightful dreams of people being murdered (after 30ih) ; extreme liveliness in m. after waJcing unusually early (20th); cramp-like tension in inferior maxillary joint (19th) ; transient threadlike stitch behind sternum (26th] ; dryness of mouth, increased thirst, pressing heavy scraping feeling like commencement of heartburn in stomach, nausea, disposition to vomit, flatulent distension, rumbling in bowels, frequent yawning (23rd, 22nd, 19th, t6th, and 15th)." '* The time of the appearance of these phenomena varied from \ — \ h. to half a d. Generally they rapidly disappeared in a few seconds or minutes.' "From the 14th dil. down to the ist trit, the symptoms increased and gained^ though not in exact proportion, in durability and in characteristic distinctness. After 5J of the 13th there appeared (in J h.) dryness of mouth ; tension and digging deep in r. hypochondrium as far as back, for some m. \ 2^ h. after, pressing in stomach as if from stone, with much yawning ; an h, later painful stiffness in nape of neck, worse on moving head, with simultaneous fine stitches in first and second molar and painful drawing in a hollow of upper jaw left by a tooth. 5J of the 12th taken in e. of the same d. caused (2 h. after) crawling, drawing and fine sticking in tip of r. index and thumb ; 2^ h. after, strong distension of abdomen j 3 h., cramp in 1. calf, after which, along with loud rumbling in abdomen, pressing and tension in region of r. -hypochondrium as fiir as back, relieved by emission of flatus j 3^ h., nne electric-like sritch in hepatic region, and J h. later pressure in stomach and distension of abdomen. After 5J of the nth (Nov. i6th, m.), first a cramp-like drawing in r. forearm towards joint of the radius, after which colic-like flatulent movements in region of lower ribs for 3 m. As these went off the distension diminished or became less. An h. later fine piercing stitches darted through sphincter ani. At same time hypogastrium, and particularly r. inguinal region, was painfully tense. 5 m. after, 5 or 6 fine pecking stitches deep in region of r. kidney. In c. of the same d., W, H — took 3J of the loth. An h. after he felt whilst sitting as if r, inguinal region was swollen. In coughing it was as if a portion of bowel pressed firmly on that part. Later there appeared pressing in stomach and frequent loud rumbling in belly. After 3J of the 9th (m. of 17th) digging and crawling in tip of r, thumb as with fine point of a needle (for to seconds, returning in a few m.) ; J h. after nausea and heartburn with pressing in stomach. The pressing extended to the spinal column and was increased by inspiration. After 3J of the 8th (in e. of same d,), drawing and tension underneath 1. great toe, returning several times at short intervals \ \ h. after, sensation of pressure and fine needle-like stitches deep in region of r. kidney (as after irth dil.) j violent stitch along urethra ; j h, after, stitch in tip of r. index ; 5 m. later

• This last pltcnDmenoc coDtinued 1^ ra,, ccsKd several it... and frrqucotly returned.— W. H.

extremely painful stab as lY from a knife in fossa navicularis; almost simultaneous itching in inner 1. canthus^ obliging him to rub it, an< fccHng of hardness in r. hypogastric and inguinal regions. (This latter symptom lasted the whole e.) An h. after, stitch in r. inguinal region ; drawing boring pain in r. half of forehead ; i^ h., slight heartburn^ feeling of distension in stomach ; prickling crawling in tip of r. thumb ; 2i h., nausea, heartburn, pressing in stomach as if from stone^ inclination to vomit, distension of belly, frequent yawning. The sym* ptoms last named lasted J h. whilst sitting quietly, and ended with emission of flatus, to which loud ringing in ears was suddenly added. The following n. prover slept well, woke> however, contrary to his habit at 4 a.m., quite lively and as if he had slept enough. A few m. after waking, he felt a gentle sticking and digging in tip of r, thumb and ring and index fingers, followed by threatening heartburn ; he then slept again quietly till 7 a.m. 5] of the 7th, which he took directly after waking, remained totally inactive with the exception of a beating cramp-like pain above 1, external ancle towards tendo Achillis (during the siesta).

L At 4 p.m. took 15 gr. of 6th trit. In J h. crawling in tip of r. thumb ; lips and mouth became dry ; 2^ h., pressing and scraping in stomach as if spoiled ; then heartburn, as from a red.hot cinder^ lasting j h,, and a few transient tearing stitches in r. index. Next m. (19th), as he repeated same dose same phenomena appeared in same order. The pressing in stomach, which oppressed the breathing, was accompanied with rumbling in epigastrium, dull pressure in back close to last dorsal vertebra, transient threadlike stitch below sternum running along its edge, and subsequently painful distension below navel (like flatulent colic), relieved in i h. by emission of flatus. On e. of same d. he took 15 gr. of the 5th. Thereupon appeared in course of 6 h. these symptoms in the following order : — Distension of abdomen ; hard pressing in the hypogastric region ; on breathing deeply feeling as of tense band around hypogastrium j cramp in calf returning regularly at short intervals ; transient stitches in r. groin ; painful tension of tendons on 1. side of popliteal space while sitting quietly ; frequent fine stitches here and there in skin as if nettlerash were breaking out ; bursting as of small bubbles, creaking and crepitation in r. ear, lasting 1^ h. ; at last violent contractions of heart with intermittent pulse ana filing of oppression in lower portion of pectoral cavity, as if lung had not sufficient space to expand itself {\ h.) The same dose repeated on m. of following d. (20th) caused only feeling of nausea as if from an empty stomach j later, pressure in stomach and pinching (aggravated at intervals] in r. groin. 15 gr. of the 4th (taken on e. of 20th) produced dryness of hard palate and slight heartburn, repeated on m. of 21st, with painful pressure in stomach which at times oppressed breathing and continued i — 2 m.» then ceasing 4 — 5 m., and again returning, was troublesome whole forenoon. This (cramp-like) affection of stomach returned in following e. after W. H — had taken in same way 15 gr. of the 3rd, only more violently. Pain extended across region of inferior r. ribs as far as back ana shoulders. It returned again zo times with frequent yawning i even after he had slept quietly, on awaking

next m. (22nd) it occurred again several times. W. H — again took IS gr. of 3rd. The affection of stomach just described soon returned again, and once more 2 h. later. Besides this, yet independent of the affection of the stomach, at all events not simultaneous with it, there appeared after this dose : — Itching gnawing inclining to rub in tip of r. thumb; distension of abdomen with feeling of nausea ; stitch through pectoralis major in direction of shoulder-joint ; transient stitches at lirst in inner anicle, then in r. tcndo Achillis i violent stitch over symphysis pubis towards r. groin. The above dose was repeated at 4 p.m. The following symptoms appeared in the 3rd and 4th h. after its exhibition : — Crawling in tip of r. index ; pressing pain below sternum, immediately after which the stomach cramp of yesterday and early to-day (4 periodical attacks, which though longer were less violent than previous ones) ; transient stitch in region of r. eyebrow horizontally through brain , after which again stomach cramp for a m. The following n. W. H— slept well ; awoke however in m. (23rd, 4 a.m.) much too lively, and felt at once itching sticking in r. great toe, then 18 painful stitches below r. clavicle (from before backwards); several fine gnawing itching stitches in r. heel, and at last a very sensitive stitch deep in r, nostril. He tried this m. the 3rd trit. once more. Sensitiveness of r. spermatic cord ; sticking as if from a fine splinter in palmar surface of r. thumb; transient stitch in r. ankle — were the symptoms which he afterwards noticed, jss of the 2nd, which he took towards e. of same d., resulted only in feeling of nausea with frequent yawning, and transient stitch in r. shoulder-joint. After repeating same dose next d. (24th) he felt pressing in stomach, with fits of nausea and loud rumbling in belly lasting 5 m. \ then for { h. cooling burning in the stomach, which gradually died out ; lasting cramp-like tension in tendons of back of 1. wrist. In this way the prover at last came to the ist trit. He took in m. of 25th ^ss. (An h. before taking it he suddenly felt an extremely violent stitch in 2nd phalanx of r. index ; it seemed as if part would be torn off.) Beyond a transient stitch in hepatic region (after dinner) and several extensive stitches in front and middle of r. thigh and below nail of 1. thumb he noticed on this d. no symptoms. They appeared so much the more numerous, however, on the repetition of the same trit. (26th and 27th, 5SS, 28th, 3J). They are summed upas follows : — Feeling of dryness in mouth ; mouth is moister than usual whole d, ; mouth is suddenly filled with tasteless fluid ; in e. when masticating a fine stream of dear saliva spirted out of his mouth; pressing in stomach; rumbling in epigastrium ; after dinner and a walk in the open air nausea, proceeding from stomach, lasting an h., with frequent yawning, thirst, increased flow of saliva in the mouth and prostration of body and mind, — ^at same time transient stitch in tipofl, thumb and cracking in 1. ear, with feeling as if tenacious moisture were flowing out of latter ; weakness of

• In the home of the prover — the Austrian frontier of the Budweiser district in Bohemia — rhe country-people are in the habit of applying kitchen salt as a remedy for nausea, when accompanied by water-brash (thcj- call it Hervwurm), and witti good results. W. H — himself has once in his youth instantly removed the evil with one single dose.

memory ; great distraction ; fine stitches in r. meatus auditorius ; tension in 1. sterno-mastoid, with simultaneous roaring In ear, after a walk ; in m. in bed, violent drawing tearing pain in tendons above the inner 1. anlde, immediately followed by a quite similar pain in tendons above wrist joints i cramp-like drawing in I. arm, just above the processus anconxus (resting) and on inner surface of radius above both wristjoints ; Sticking drawing in r. tendo Achillis ; in n. of 29th — 30th very violent drawing tearing pain in region of 1. ischiatic notch, and immediately afterwards similar pain below head of 1, fibula. The sexual inclination was throughout the entire proving unusually small.

£, So early as Dec. 3rd of this year W. H — began a new series of experiments with the attenuations. From 3rd to 6th Dec. he took daily m. and e. 20 gr. of 30th trit. The result was (3rd and 4th) drawing sticking pain, frequently recurring, on palmar surface of tip of r. thumb, and especially of r. index, during rest ; sometimes a similar pain below nails and at their roots; (5th) after same, pressing in stomach, as if from a stone,**^ with feeling of nausea, accompanied with an extensive stitch above the symphysis pubis towards r. groin ; same c. a drawing pain in region of r. inferior ribs towards back, as if from a round but rough body, lasting several m. ; (6th) in e., drawing beating pain as if from commencing suppuration in tip of r. index, with frequent emission of flatulence. 7th to qth, 30 gr. daily m. and e. of 25th. yth. — Half an h. after e. dose fine stitches at measured intervals, occurring simultaneously with pulse deep in region of r. kidney (comp. J6th and 17th Nov.) ; followed by drawing sticking pain, repeated at short intervals, in metacarpal joint of first phalanx of r. thumb ; 3 h. later great distension of epigastrium, with pressing and pain in stomach, as if from fine needle-points, which appeared to penetrate from stomach to below breast-bone in taking deep breath. 8th. — Taking of m. dose was followed ^ h. after by loud grumbling and rumbling in 1. side of breast close to stomach ; subsequently drawing sticking pulsating pain in metacarpal joint of K thumb, and fine flying stitches here and there in skin, particularly in middlcof anterior surface, of r. thigh, like electric sparlcs, leaving behind unpleasant feeling of coldness (comp. Nov. 19th). yth. — In forenoon, violent stitch in abdominal wall ^ in. from navel on r. side ; cramp-like drawing sticking on inner surface of 1. leg followed by a few violent stitches in first phaUnx of r. index along with strong electric shock of whole of r. arm. During dinner he felt on inner sur^ce of r. cheek an open blister in which the warm food caused a burning pain. Afternoon, frequent prickling crawling in 3rd phalanx of r. index. loth — 12th daily, m. and e,, 30 gr. of 20th. loth. — During whole d. scratching in stomach, as if he had eaten something indieestible. iith. — Sensation in rectum, as if a foreign body or rough harcT faeces were lying in it, with uninterrupted looseness of bowels. 12th. — No symptoms. 13th to 15th. — Twice daily 30 gr. of 15th. 13th. — Throughout d. much accumulation of saliva in mouth. Next m. he awoke suddenly from intolerable

• Remarkable is the connection between the affection of the stomach and ilie tip of the index Anger and the thumb of cbe r. hand, which khowcd itvelf throuj^hout the whole of the proving.^W. H,

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3S8

itching in anus, which extended as far as neck of bladder and prostate gland and continued 7 — 8 m. 14th. — During d. mouth unusually moist. At n. woke suddenly with violent urging to stool ; it resulted in a thin pappy stool, followed by painful distension of abdomen above symphysis pubis, as if from flatulence. At same time he felt rtty weak ; tongue was stiff and, like hard palate, uncommonly dry, pulse accelerated, small and weak. In tip of r. thumb he experienced a prickling grawling sensation. In } h. he fell asleep. Next m, he liad another diarrhccic stool. 15th.— Throughout whole of d. scraping feeling in stomach with white-coated, dry, stiff tongue, without ihint. Toward e, cramp-like drawing in r. femoral region j looseness of boweJs. idth and 17th, m. and c., 30 gr. of loth. x6th. — Forenoon, prickling itching in tip of r. index ; fine stitches in r. tonsil ; twitching iu anus. In e. in walking stitch from horizontal ramus of pubes through r. hipjoint ; JO m. a^erwards, sitting, similar but weaker pain in same place in i. side. About 11 p.m., diarrhoeic stool. About 3 a.m. he awoke with urgent desire to go to stool ; latter was yellowish brown and pappy, and smelt strong, followed by distension of abdomen, with loud grumbling and feeling of hardness. In turning over he noticed a sound proceed.ing from stomach resembling croaking of a frog. At same time he felt weakness and inquietude in whole body ; tongue and palate were stiiF and dry. On attempting to fall asleep half r. side of body was shaken as if by a violent electric shock. An h. after he quietly fell asleep. At 7 a.m. there again occurred urgent deure to stool, and diarrhora with much flatus in long streams, grumbling and feeling of hardness in belly. 17th. — About 11 a.m. a diarrhoeic stool ; after dinner pressing in stomach, dryness of mouth, frequent loud rumbling in epigastrium. i8th and 19th, m. and e. 30 gr. of 5th. ]8th. — In course of d. two diarrhccic evacuations. £., flying stitches in r. spermatic cord ts hr as testicle. At n. again diarrhoea, followed by prickling crawling in tip of r. index, alternately with itching in anus, as if an insect were creeping out ; sticking in tendo Achillis first of r. then of I. foot ; at last colicky pain in hypogastric region, as if from flatulence, igth. — Towards e. stitch in r. pcctoralis major, as if from an electric spark j an h. later similar pain in r. nipple, followed by feeling of tightness, as from a band, in lower third of chest, with difficult breathing; tension and sensation ot stiffness in 1. uerno- mastoid ; frequent yawning ; cramp-pain in metacarpal joint of r. thumb; iine stitch in abdominal integument ^ in. to left of umbilicus, alternating with a similar one in middle of anterior surface of thigh ; drawing pain in r. ear, 20th.— In m. 60 gr. of 4th, in afternoon 60 gr. of 3rd. In forenoon, in course of 3 h. much accumulation of saliva in mouth ; pressure in stomach ; distension of belly ; loud grumbling in 1. side of abdomen ; pain in hypogastric region, as with flatulent colic ; frequent yawning ; cracking in Lear on swallowing; sensitive stitches deep in root of nose towards r. frontal sinus ; stitches below nipples ; drawing sticking pain in metacarpal joint of r. thumb ; after dinner diarrhcea. Afternoon (1 h. after dose) sticking below 1. nipple ; \ h. later, fine stitches in 1. external canthus, as if there were sand in it ; 2 h. after, diarrhoea; at last feeling of soreness in 1. nostril with difficulty in inhaling air

through it. Throughout whole d. he had sensation in tongue, as if he had eaten something astringent which blunted sensitiveness of papDlx. ^. Dec. list, 9.30 a.m., took i scruple of kitchen salt. 5 m.> feeling of scraping and pressure in stomach, loud rumbling and grumbling in 1. side of abdomen and about stomach, with loathing and frequent yawning j 3^ h., frequent painless twitching in muscles ot 1. side of chest, below axilla; 5 h., sensation in anus, as if small air-bubbles ^were passing through, one at a time; i h. later, in lying, tension in ^cardiac region, followed by a sudden extremely violent concussion of whole I. side of body -, prickling and crawling in tip of r. index ; and such weakness in thumb, index and middle ^nger of r. hand that he could scarcely hold the pen (lasting 10 m.). In c, great relaxation of body and mind, distraction, dull absence of thought, accompanied with pressive pain in stomach and frequently repeated fits of nausea. Slept well during n, till 4. a.m., when he had very violent contractive pain in hypogastric region, lasting several m. and returning (every 15 m.) 3 times ; tingling, as if asleep, in thumbs index and middle finger of 1. hand (they were as if dead for 5 m.) ; thereupon painless twitching in 1. pectoralis major and fine stitches below skin in hepatic region ; lastly emission of stinking flatus. About 6 a.m., call to stool and evacuation of a pappy yellowish-brown, very offensive stool, mixed with little whitish-grey lumps (almost like masses of tubercle). 22nd.-^ a.m., another scruple. 15 m, after, grumbling in epigastrium (often during d. and always returning with yawning) ; during whole d. frequent crawling in tips of fingers and fine stitches here and there in skin. 23rd. — 9.45 a.m., 3SS. 5 m. after, tension in 1. groin, with rumbling in belly ; \ h., gentle drawing in J. tonsil, simultaneous cramp pain and roaring in I. ear (for 10 m.) ; 2 h., drawing tension in middle of anterior surface of 1. thigh, hindering walking ; 2^ h., pressure in stomach and in hepatic region, with contraction of chest and frequent flow of saliva in mouth j yawning; an itching stitch in heel; 2} h., thin, almost diarrhoeic stool, thereupon loud grumbling in belly, heartburn, and pressure in stomach (lasting several m., frequently returning at short intervals). The pressive pain extended from stomach as far as back, and caused slight contraction in pharynx ; at same time head was dull and clouded, and prover was overpowered by a very peculiar irresolution even in regard to the most indifferent things. 3J h., pressure and tension on spot size of a thaler, below r. false ribs, for 3 m. ; sh ^'^ transient stitch from nape of neck into occiput and two very penetrating stitches in 1. thigh in neighbourhood of scrotum; digging pain above 1. eyebrow deep in brain ; 6| h., thread-like sharp stitch penetrating from below upwards in r. edge of scapula (comp. Nov. 8th) ; 7 h., transient stitch in 1. internal canthus, alternating with a similar one in the ramus of r. ischium ; twitching in inferior orbital ridge of r. eye. In e. tension in nape ; stitch in 1. great toe ; prickling itching in orbital ridge of 1. eye (towards external canthus) ; digging pain deep in hepatic region. In sitting sticking, cutting, extremely violent and lightning-like pain shook whole body, which began behind the anterior spine of r. ilium and spread partly downwards over trochanter towards anterior and external surface of thigh, partly upwards acro<^

back as far as neighbourhood of scapula ; a few m. afterwards there appeared an itching and crawling in first phalanx of middle finger. In m. after waking, a similar sticking cutting pain as on previous c. shook body, which, however, proceeded from 1. hip ; { h, later, fine sticking in back of thumb close to root of nail coming with each beat of pulse and frequently returning, thereupon (after a very thin stool) a similar itching stickmg on dorsum of I. foot. 24.th. — Took in m. another 35s. Immediately after taking it, shaking, loathing, with rumbling in the bcUy and frequent yawning ; an h. after feeling of chilliness in whole body, with frequent shivering, and accompanied with loathing and yawning ; prickling itching in r. ridgeof lower jaw j 2 h. after burning in stomach, with oppression of chest ; frequent yawning ; 7 h. after stitch as if with a needle in root of nail of r. great toe ; 13 h. after similar stitch in r. patella ; spasmodic pains in I. side of belly, lasting 1 — 2 m., relieved by emission of flatus, frequently returning at short intervals. On following m., 25th (without medicine), prickling crawling in tips of several fingers ; violent stitch extending from 1. clavicle down side of breast ; in course of d. and even next, 26th, great sensitiveness of teeth (particularly in lower jaw) whilst inhaling air ; raw place in inner surface of r. check, causing burning pain in contact with warm food ; irritability of edges of eyelids and their mucous membrane. 27th. — In m. 5J. Soon after taking it strong rumbling in 1. side of belly. Little appetite at noon. In afternoon stitches in 1. heel. In e. painful pressure in stomach with oppression of breathing and feeling as if diaphragm were pressed against lungs and thereby hindered their expansion, with frequent yawning, and rumbling in belly. 28th. — In m. jiss. 2 h. after, loathing with shuddering, which recurred repeatedly even at the thought of the medicine taken ; towards noon diarrhcea, with loud rumbling in epigastrium ; later, pressure in stomach and hepatic region with constant rumbling in epigastrium ; dull pressure in occiput and nape (1.) continuing i h. i squeezing, drawing, sticking pain in I. groin j diarrhcea again in e. with subsequent strong rumbling in belly. From Dec. 29th to Jan. 13th medicine was suspended. The diarrhoea came during the next 4d., each d. a few times. On the 5th d. the urine (which had hitherto been quite clear and normal!) showed a dark green colour (as of an infusion of marsh mallow); during its emission it caused slight burning. The whole d. prover was troubled with pressing pain in stomach and Itver. The pressure was aggravated periodically, and was felt as far as the back. These symptoms increased in intensity during the 2 following d. The pressure in the liver and back close to the spinal column became very painful ; the urine became as black as a saturated infusion of roasted coffee and perfectly opaque (urina Uteri' corum) i the colour of the skin, however, showed no alteration ; at night he frequently awoke on account of repeated accumulation of saliva in the mouth. Only 8 d. after did the urine become again dear and of a natural colour. The hepatic symptoms were accompanied temporarily by pains in separate circumscribed parts of r. side of chest.

€. Jan. X4th, 1844, took 5SS. Throughout d. frequent loud rutnbline in r. side of chest. In c. (after a short walk) great weakness in all limbs, especially in arms, with feeling of faintness in stomach and great

inclination to sleep -, constant grumbling in 1. side of bcll)r ; prcssive sticking in the baclc close to spinal column corresponding to part of posterior sur^ce of liver. The stitches appeared periodically every J h, and extended as far as below r. scapula. Thereupon frequent yawning i fine stitch in tip of r. index ; chilliness, as if from taking cold, over whole body ; great sensitiveness of teeth, especially on r. side, to air. Next m. much accumulation of saliva in the mouth with frequent spitting. 15th. — In m. took another 555. In e. frequent emission of flatus with odouruf rotten eggs. i6thand 17th. — Inm.jj. On i6th frequent loud rumbling in 1. side of bclJy, with flying stitches below], scapula, i 7th. — Pain as if strained in r. pectoralis major in moving i i h.later, p.m., drawing-sticking below upper part of sternum; looseness of bowels i at n. flow ofwater out of mouth. 18th. — In m. jij. In i h. loathing, inclination to vomit, increased flow of saliva, shivering ; I h., pappy stool. The whole forenoon shivering, absence of thirst, increased flow of saliva and frequent spitting j at same time unfitness for mental labour, want of ideas, stupidity. In e. prickling itching in back of r. index, and on lower edge of r. orbit, shivering, frequent yawning, rumbling and croaking in belly (continuing whole c.). 19th. — In m. took Jss. With this dose W. H — concluded his proving. Although the action of this dose, on his assertion, extended over an entire month, yet we find only those symptoms furnished which appear immediately after taking the medicine and during the 4 following d. They are as follows : — Shuddering and loathing, with burning at stomach and increased secretion of saliva (^ h.) ; pressure on chest, repeated shuddering, itching in r. external canthus, rumbling in abdomen, urging to stool, diarrhoea (an h. after) ; want of ideas, dulness of intellect. In e. pressure in back on 1. side close to spinal column (corresponding to posterior part of 1. lower ribs) as far as scapula (comp. Jan. 14th) ; pressure in stomach and in hepatic region. 2oth. —The pressure in back and stomach was troublesome whole forenoon, accompanied by increased flow of saliva in mouth, rumbling in belly, and frequent yawning. In e. the same phenomena. Besides this, itching and fine stitches between scrotum and I. thigh ; sticking itching in 1. internal canthus; several violent stitches in r. hip. 2jst. — In m. painful spasm above symphysis pubis, appearing repeatedly ; cramp-pain in r. temple extending into the teeth ; urgent call to stool, which threatened to overpower the sphincter against the will of the prover. However it resulted merely in a pappy, dark brown, very oflensive evacuation. Dryness in mouth. At n. after the usual draught of beer, painful colic in hypogastrium as from wind. 22nd. — Feeling of hardness in hypogastric region. At n. much flow of saliva. 23rd. — In m. thin pappy stool. In afternoon flying stitch from I. pectoralis major towards clavicle. In c. another thin pappy stool. 24th.^At n. much flow of saliva out of mouth and another thin pappy stool. (Ibid,)

1. Dr. Reisinger began his proving with the 3X trit. After he had taken daily for 8 d. 2$ gr. without the appearance of the least alteration in his state of health, he proceeded to a similar dose of the 2X trit. This appeared to him just as little productive as the former. He now took the i^ fasting, i drachm daily. Beyond an inaipid salt tastt;.

which continued for eome time after its exhibition, slight griping in belly and pappy stools, he noticed nothing from this trituration aJso. All experiments with the dilutions, which he took in the course of 6 weelcS) beginning with the X5th down to the lat, in doses of 50 df. daily, remained without result. At last he determined upon trying a saturated solution (of i oz. kitchen salt in -^ pint of water). He had scarcely swallowed this disgusting draught when he was seized with such a violent loathing that he immediately vomited it all up again. He felt indisposed the whole d., had pressive pains in head, insipid sour taste, accumulation of water in mouth, nausea, and inclination to diarrhoea. After a few d. of rest, during which his previous good health returned, he repeated the last experiment. The same phenomena reappeared. After he had subjected himself to a third proof, he experienced an unconquerable repugnance to the saturated solution. He consequently returned to weaker solutions, which, however, like all the previous small doses, evinced no action on him. Rg— * therefore holds chat he is insensible to the dynamic action of sale, and ascribes this to his habit of eating his food much salted. {Ibid,)

1. Dr. Simon Reiss proved salt on himself and his housekeeper, Marie E — - Both provings deserve our respect in a high degree, even if accident should have supplemented the copious array of symptoms furnished by them. According to the character which R — sketches of himself, he is 33 years of age, melancholic-sanguine temperament, with black eyes and hair, pale brown complexion, big-boned, middle height, with inclination to corpulency ; in childhood and early youth healthy, suffered from frequent pollutions in his adolescence, and became affected (probably in consequence of mercurial treatment after a chill) with rheumatic swelling of joints of wrist and fingers, which was followed, after twelve weeks of partly successful allopathic treatment, by hemorrhoids that disappeared in a month. Only from time to time slight return of rheumatic symptoms showed themselves. Since his 30th year he has been, with the exception of a periodical almost monthly recurring discharge from r, ear which lasted z to 2 d., quite healthy. His appetite is good. He drinks after dinner and supper wine and water, coffee twice a d. i smokes tobacco ; has an evacuation every S. after dinner ; sleeps well generally from midnight till 7 a.m., and has not subjected himself in his mode of living to. any (restrictions during the time of proving,

. , tf, Nov. 14th — 18th, 1843, took 3 times a d. 100 gtt. of 30th dil. '15th. — II p.m., call to stool with feeling as if rectum were forced out^ hard friable stool ; after stool shooting in anus, especially in walking } after midnight, sleeplessness. 16th. — Frequent emission of ffatus throughout whole d. In e., 10 m. after takijig dose, fine shoots in different parts of body, particularly in tip of r- thumb, 1. side of navel, and thighs. 17th. — Frequent emission of flatus through whole d. Towards 1 1 p.m., pressure in r. eye ^ feeling as if a mist were before bi>th eyes, returning 3 times in quick succession. 18th. — Frequent emission of flatus during whole d. About i p.m. unusually hard, dry, friable stool, without pain i copious micturition during stool \ micturition every 10 m.^ with sensible shoots along urethra from behind

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-forwards, 19th-— 24th. — Every d. 100 gtt. m> and e. of the 29th to a3rd dil. i9Ch. — After dinner hard, firm, unusual stool with tenesmus ; less frequent micturitioo than on previous d., yet more than usual. 20th. — In forenoon, on walking, flatulence, with feeling 2$ if looseness would come on, 3 p.m., urging to stool s stool scanty, hard. 2ist. — Uneasy sleep, strong palpitation during sleep which awoke him. (It was better after a glass of water.) In m.> whiJe walking, itching in anus. Frequent emission of flatus, with feeling as if moisture escaped with every emission. Afternoon, feeling as if looseness would ensue ; call to urinate, and six emissions of urine at intervals of i h, soon a/ter dinner. 22nd, 23rd, and 24th. — M., headache (after smoking), which continued whole forenoon, and only disappeared after dmner and drinking cofTee i no stool. In c. particular appetite for fish ; at first mouthful such loathing that it was impossible for him to eat more of it i on the contrary appetite for white bread, which was very tasteful. The loathing of Ash first disappeared after drinking black coffee. 25th. — In m. 22nd, afternoon 21st, e. 20ch dil. Tobacco is not at all tasteful to-d. (the last few d. this was more or less the case). 3 p.m., stool with tenesmus, first hard dry stool, then soft ; afterwards burning in anus in walking. On 26th, the i9tb, 18th, ijthy i6th ; on 27th, the 15th, i+th, 13th dil. 27th. — After dinner easy, very scanty, soft evacuation. On 28th, 12th, i tth, and loth dil. Forenoon, frequent emission of flatus i pinching in belly as if before looseness of bowels ; after dinner no stool > frequent micturition. On 29th, 9th, 8th, and 7th diL After dinner soft stool. In e. in bed, lo m. after taking med., burning in the scrobiculus cordis (this seemed to lie between stomach and external integument) ; immediately after feeling of wcaknc&s, like paralysis, of r. leg, so that he believed he could not move the limb; burning coldness {sic) in r. patella. Dec. ist, 2nd, and 3rd^ the 3rd, 2nd, and ist dil. 2nd. — £., burning in stomach (apparently in external coat) i spasmodic contraction of stomach ; paralytic heaviness in both hands as if asleep; in ring finger of 1. hand, on side of middle phalanx, shooting pain, lasting about 10 m. ; fine shoots in various parts of skin of whole body (resembling pricks with a needle), soon ceasing. Disinclination to coition (since 8 d.) 3rd. — Frequent micturition whole d. ; frequent emission of flatus, particularly in forenoon. 4th. — 20 gr. of 3rd trit, 5th. — In walking squeezing shooting obliquely through base of bladder, continuing several m. ; soon after, shoots in rectum; frequent emission of flatus, especially in forenoon. For 2 h. after dinner every \ h. urging to urinate, with emission of clear pale urine, later at rather longer intervals, lasting on until e. ; frequent chilliness in different parts of body throughout whole d. 6th. — -Sour taste in mouth, continuing till e. ; frequent micturition after dinner. On same d. in e, took 20 gr. of 1st trit. 7th. — In m., in bed, weakness and heaviness in limbs, disappearing after rising ; cheerful humour > frequent micturition after dinner. ^ ^

A. Dec. 8th. — Took 15 gr. of the raw material. 9th and lOth. — Took 3 drachms of same. 8th and 9th. — No symptoms. lOth. — Frequent micturition after dinner; stool loose, with tenesmus; thereupon shooting in rectum, lith. — E.^ 4 drachms. 5 m. after taking the above

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frequent yawning, recurring every m., which up till 9 o'clock bccunc much more violent and ultimately spasmodic. After drinking wine it ceased. During the yawning constant nausea ; weakness of hands ; itching over whole head ; fine stitches in di^rent parts of bodv ; frequent shuddering over body ; pale complexion and lips i loss of appetite. Food has no taste whatever. After dnnking wine several times taste returned, and appetite also was aroused ; only there remained still great weakness and sleepiness, so that he was obliged to go earlier to bed than usual. I2th. — In m. hoarseness, without pain. 1 1 a.m., fine painful shoots through tip of r, thumb ; in second phalanx of thumb pain as if dislocated. Distraction while conversing. 13th and 14th. — -In e.,about 7 p.m., 3 drachms, rjth. — Took same dose about 10 a.m. A few m. after that nausea and vomiting, with dryness in mouth and burning feeling in stomach; loathing of food i very great thirst for wine ; after wine more appetite. After dinner call to stool ; the latter was consistent, i z p.m., again 3 drachms. Soon after, fine shoots in various places in body, rapidly passing off ; shouting in sleep. 1 6th. — Frequent urination whole d. Urine pale, clear. 6 p.m., 4 drachms. 5 m. after yawned 8 times at short intervals i then accumulation of water in mouth and spitting of same i after that hiccough, alternately with yawning ^ ultimately hiccough only, lasting I h. ; all this time nausea and inclination to vomit, with total relaxation and weakness of body ; contraction of skin in vertex ; in L half of forehead pressive pain ; some h. after, great dryness of mouth ; uneasiness in whole body, which allows no rest anywhere. He was morose, went to the theatre, but was obliged immediately to come out again on account of inquietude and discomfort j thereupon great weakness, particularly in legs. Desire for wine ; he could scarcely wait till it was brought to him in the hotel ; in a few m. he drank a pint with two pints of water. Unquenchable thirst ; loss of appetite » loathing of animal and other food ; avidity for bread. He ate four small loaves of white bread, with constant drinking and involuntary movement of muscles of mastication, and great appetite. Distension and swelling of abdomen, which prevented further eating. He still had good appetite, but only for bread, after which great sleepiness. He slept soundly. He was awakened about i a.m. On aviraking, pappy taste in mouth, with much thirst. He drank 2 glasses of water, went out, came back, and slept quietly till m. 17th. — Frequent micturition whole d., especially after dinner. After dinner, in sitting, cramp pain in 1. index and thumb (first phalanx), particularly if he leaned arm upon anything ; soon after that same pain in r. thumb j weakness of hands. He was quite unable on account of weakness to play on the piano. Stool small, although there was feeling as if he should have an abundant one; shoots in skin in different parts of the body; frequent emission of flatus, offensive in m. but not after dinner; pale lips ; dissolute look. Tobacco is distasteful. i8th. — After supper obtuse shoots in r. hand, especially in thumb and index. He could not keep hand still ; it moved involuntarily as in chorea, at same time it was so weak that he was unable to hold cards m playing' Stool insufficient. 19th.— 10 a.m., burning shooting in anus and feeling as if it were rav

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especially in walking. In c. he could scarcely sit on account of painful protruding piles. 11 p.m., 3 drachms. In bed yawning, hiccough, nausea ; late falling asleep, early waking. On awaking r. leg was weak, as if he could not raise it, from knee downwards particularly. 20th, 5 p.m., tickling in larynx and short dry cough. Weakness during whole d. Was awakened towards 2 a.m. Whilst awaking, cough from tickling in larynx. Each time he expectorated a considerable quantity of frothy saliva. The inclination to cough was increased by lying on back. Yawning alternately with coughing. 4 p.m., cutting in abdomen, quickly passing off, with urging to stool, as if looseness would come on ; however, there came only 2 consistent lumps j after that tenesmus; dull shoots below r. nipple, likewise in belly to r. of navel ; squeezing pain in second phalanx of 1. thumb. About 6 a.m. all the symptoms ceased, and he slept on quietly. 2ist.^ii p.m., great inquietude in legs, beginning at knees, which would not allow him to sit. He was compelled to rise and walkabout, on which the uneasiness always went off, 22nd. — Made a journey into the country. About 6 p.m. in the carriage frequent fits of yawning one after another, thereupon hiccough six times; tickling in throat, which provoked coughing; dry cough for an h. ii p.m., heat and uneasiness in legs, which scarcely allowed him to remain in the carriage. As soon as he arrived at the end of his journey the uneasiness and heat also ceased. 23rd. — On the road home, throughout whole forenoon, nausea, frequent inclination to vomit ; loathing of tobacco, wine, and beer ; absence of appetite. Not until following d. at dinner did appetite return. The frequent emission of urine and flatus ceased after a few d., ; there only remained a disinclination to tobacco smoking. The loathing of the medicine was so great that he could not think of salt without feeling sick. Dislike to society. 31st, — Before going to bed at n. took 4 drachms. Directly after, inclination to vomit ; repeated yawning ; compression of the scalp and of the head, beginning at the temples; pressive feeling from stomach upwards into pharynx. Awoke at 5 a.m. quite lively with much thirst. Jan. 1st, 1844. — In forenoon emission of flatus, with feeling as if soft stool would follow. After dinner, urging to urinate, with frequent emission. Before going to bed again, 4 drachms. At 5 a.m. awoke in a good humour. 2nd. — Forenoon, much emission of flatus. After dinner frequent micturition. When he puts his hands into his coat pockets, prickling with painful feeling as if asleep in hands (during whole d.). 1 1 p.m., uneasiness in the lower limbs which will not allow him to sit, especially strong when laying the hands on a hard body ; cramp-like pain in r. thumb. 3rd. — Before going to bed 3 drachms. Awoke at 5 a.m. perfectly refreshed. In riding in a carriage into the country, each time he exposed his nose to the open air much watery secretion of mucus, now in r,, now in 1. nos* tril. 4th — 9th. — No medicine and no symptoms.

c, Jan. loth. — M., afternoon, and e., 20 gr. of ist trit. Pain as of dislocation in r, wrist-joint and in last phalanx of index, with weakness and feeling as if asleep in both hands, especially when he laid them on a hard object or put them in his pocket ; throughout whole d. fine shoots, which rapidly disappeared, in different parts of general integu-

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mcnt, with itching obliging him to scratch, especially on toes, r. index, lips, gUns penis, and prepuce, and in axilla ; much appetite. I Ith. — j a.m., wide awake and completely refreshed. Took. 3 doses each of 20 gr. of 2nd trit. Fine shoots in various parts of body, especially lips and through whole length of urethra ; feeling as if asleep in I. hand and arm ; painful weakness in arms ; tension above knee, with feeling as if lower limbs were too short, in going upstairs ^ constipation -, sour taste of saliva ; frequent accumulation of water in mouth. 1 1 p.m., much thirst. I2th. — Fine shoots in various parts of the body, quickly passing off. 9 p.m., took 5iij of the raw material. Directly after, iiH clination to vomit; yawning, with lively humour, is disposed to make nonsense ; in sitting, great uneasiness in lower limbs ; burning shooting on back of toes ; in standing, feeling as if net were before eyes, not lasting long, recurring three times ; feeling as if 1. eye were smaller than r. ; fine shoots in skin, especially of lips, in axitlz, on breast; scraping feeling in pharynx j pressive pain in r. half of bead towards vertex, of short continuance; much thirst, particular desire for wine ; involuntary movements with r. hand ; shooting in rectum, feeling as if raw in same part, so that he cannot sit ; redness round about anus. 13th. — In m. on going out much secretion of mucus from posterior nares obliging him to hawk constantly , much hawking of watery mucus ; emission of much otfensive flatus. After dinner, urging to stool , hard friable stool j burning in rectum in walking throughout d. 14th. — M., in bed, feeling of weakness, as if paralysed, in both hands and r. foot, disappearing after rising ^ emission of much offensive flatus in forenoon ; frequent micturition whole d. ; urging to stool as if looseness would come on, all d. ; after dinner, consistent stool. Very much appetite ; ate almost twice as much as usuaL 10 p.m., great uneasiness with shoots in feet, so that he cannot remain seated and is obliged to keep moving the feet backwards and forwards. In going about this is relieved. Much thirst, particularly for wine. He has oecomc during the last few d. remarkably stout and looks very well. Great desire for coition, ijih, — Emission of much flatus; frequent micturition, particularly after dinner. Bread tastes the best j he can scarcely eat enough of it. Much thirst for wine. All wines appear sour to him, although others do not confirm this. l6th. — In m. in bed feeling of weakness of r. inferior extremity as if it were lame; relieved by standing up. 17th. — Boil on lobe of I. car, which pains very much, burst in 6 d. and discharged pus and blood. In consequence of taking cold was seized with influenza, which confined him to bed. From this period all the salt symptoms ceased. For the subsequent 8 d. he had still constant soft evacuations. From time to time there showed themselves, even after four weeks, many of the previous phenomena, particularly weakness of r. hand in holding an object, and uneasiness in legs about 10 to 1 1 p.m. {J6id.)

1. Marie E — , housekeeper for Dr. Reiss, is 24 years of age, vaccinated, brown hair with black eyes, bright complexion, choleric temperament, active mind, strong constitution, menstruated in her thirteenth year. Through suppression of the catamenial flow by a cold bath she became chlorotic and affected with leucorrhoea, which disease

3<57

continued up to her i8th year. From that time till now she has been perfectly heaJthv. During the proving she has not made the least alteration in her mode of living. She took salt only from 13th to 16th Jan., and always about 10 p.m.; 3J on 13th and 5ij on 14th, i8th, 20th, 31st, 24th, 25th, and 26th. The following symptoms are given in her own language.

a. "13th. — Soon after taking dose much thirst, 14th. — M., after rising pinching in belly, as if looseness would come on ; a few m. after twitching and quivering of r. upper eyelid ; much emission of flatus whole d, ; uneasy sleep full of dreams ; frequent micturition during n. i5ih, — M., heaviness and dull feeling in head, as if she were downright sleepy ; strong shooting in r. temple towards front j feeling as if upper r. eyelid would fall down ; heaviness and weakness of arms ; in r. wristjoint, when attempting to grasp anything tightly, shooting; sometimes she cannot grasp firmly on account of weakness of hand -, weakness of the legs ; much emission of flatus, whole forenoon. After a break^st of coffee, pains in belly, as if a double-edged knife were being worked about there, continuing i h.; towards e. chilliness over back} later much thirst. i6th. — M-, after rising, heaviness of head, though less than yesterday. After a breakfast of coffee cutting pain in belly and two loose stools ; feeling of weakness in hands and legs. When she stands her legs double under her, so that she would fall. Frequent micturition, in forenoon. After dinner all the symptoms were relieved, 17th. — After drinking coffee cutting pain in belly and two loose stools $ less emission of flatus than yesterday ; frequent micturition, forenoon. E,, feeling of weakness in whole body ; the longer she remains up, the weaker she becomes, i8th. — M., after drinking coffee pains in belly without looseness ; frequent micturirion, forenoon j urine turbid, with strong smell, — it seems acrid. 19th. — Uneasy anxious sleep; frequent waking, with dread of something which she cannot describe ; after rising no desire for coffee. — After coflTce cutting pain in belly with straining and stool, frequently recurring during forenoon. — Afternoon, cutring in belly, not so violent as in forenoon ; in 1. foot above and around ankle pain, as if sore ; weakness in hands and feet. soth. — M., after coffee, violent cutting in belly. TTiis is repeated frequently during d., but not so violently as in m, 21st, — M., on rising much thirst, also during whole d. 3 p.m., cutting pain in whole head. In r. side it abates somewhat at intervals, though not entirely ; then each time it is worse in 1. side (increased in open air). On I. side pain extends like drawing from forehead over 1. eve, from zygoma down as far as angle of inferior maxilla, lasting only a few m. (This pain, unlike the former, comes each time she enters a room from the open air). E., before taking dose trembHng over whole body. There is a flush of heat up to head, with anxiety and feeling of nausea till she becomes unconscious. The objects around her appear quite different. The vertigo is relieved by keeping still. After taking the dose uneasy sleep. 22nd. — On awaking, in bed, shooting pains in whole belly, especially in hepatic region below last ribs on r. side ; at same time chilliness over whole l^y lasting i h. After drinking coffee pain in belly, not violent. At 10 a.m. weakness in hands, more marked in

feet. The pain in hepatic region comes on frequently throughout d., as well as the nausea and vertigo. About 3 p.m. same cutting pain, to and fro, in head as yesterday, but only in r. half and not lasting so long. 23rd. — M., after rising, cutting pain in belly, especially below ribs on r. side, lasting J h., also after drinking coffee, yet shorter and slighter in character ; at same time urging to stool, without result. After dinner cutting pains in whole belly, more violent than in m., lasting an h. i bitter taste in mouth and inclination to vomit. After 5 p.m. sleepiness so that she oould not sit upright. She fell asleep while sitting. After \ h. sleep she felt better, 24th. — Pain in hepatic region in walking; it goes through liver from before backwards, is relieved by bending body forwards and to r. and lasts several h. No evacuation ; urine since 8 d. turbid j for some d. lately melancholy humour, she likes best to be alone. Pale, faded look. She is notably thinner. £., after taking dose, chilliness. 25th. — On awaking and subsequently shooting pain in r. side below last ribs, continuing whole forenoon, improvea after dinner. E., it returned on going out ; on coming home again it disappeared. Stool with exertion, hard; headache, undefined, through whole d. ; at same time, although she was in a bad humour the whole d., yet she felt obliged to hum and sing to herself, she had scarcely left off when she had to begin again. (Never sings otherwise.) E., in bed, 5 m. after taking medicine, violent cutting pains in bcUy, ftequently returning, round about navel. She fell asleep and was awakened. After awaking, in bed, much thirst. On rising she had no pains ; as she got into bed pains returned. She again fell asleep and was again awakened. On getting up she felt well, only she had much thirst. As she again got into bed she became giddy, had pains in belly, with nausea. She was awakened once more, and had again much thirst on rising. As she again got into bed pains around navel directly returned. She was unable to sleep soundly any more. 26th. — In m. on rising hot twitching (?) on back of both hands and passing out by tips of all toes, with weakness of the feet, less of the hands. After rising very violent cutting in belly continuing for J h. as if everything were being drawn from behind forwards towards navel, with anxiety. The cutting was renewed after drinking coffee, after dinner, and in e. She had very little relish for the coffee. Much thirst throughout whole d., neither for water nor beer, but only for wine; loose stool in forenoon ; frequent micturition whole d. ; urine turbid and dark ; much appetite at dinner; dulness of head whole d., as if too heavy. She does not see so distinctly as usual ; the eyes seem all d. as if veiled. In afternoon great appetite for cold things (ices). Between 6 and 7 p.m. chilliness over whole body ; sleepiness during chilliness, she had to force herself to remain awake. The sleepiness was kept off by rising and walking about. She talks more and more pleasantly than usual, yet does not like it when she is spoken to. If she has nothing to say she is pensive and melancholy. Of late she has become remarkably thinner and looks pale and sunken, particularly in m. and after dinner. In e. directly after taking medicine (to-day she took the last dose) chilliness, which lasted until she fell asleep. 27th. — She was unable to sleep any more after 5 a.m. She was anxious. When she fell into a slumber, she

dreamcdi and was soon awake again. At same time she felt heat in the head internally and pains in belly, as if looseness would come on. In rising cutting in belly ^ thereupon great looseness, without straining. After the looseness violent cutting pains in whole body, especially around navel and in hepatic region. About 10 a.m. heaviness and duJncss of head with vertigo in stooping; there appears to be a thick fog before eyes, lasting till 3 p.m. 5 p.m., hot twitching {?) in whole body, alternating with chilliness. She was hot all over and yet she felt starved. Yawning during chill. After 7 p.m. she was better, only legs were still heavy,so that she believed she could not rise. After lying down, chilliness. Sheslept well, but had a heavy dream. 28th. — M., after rising nausea with vertigo and empty eructations ; heaviness in head ; prcssive pain in forehead. She can scarcely open her eyes from heaviness of the lids. Difficulty in breaching ; quick breathing whilst standing, still more in walking i appetite for coffee ; surly and ill-humoured, particularly when she addresses anyone ; melancholy ; whatever she looks at puts her in a bad humour. Thinking becomes difficult to her. When she exerts herself to think, or when she must talk much, she has sensation on both sides of forehead directly above arch of eyebrows, as if one beat with the finger on the part. On scalp where hair is parted, itching, also so much itching in both eyebrows that she was compelled to scratch these places the whole d., but chiefly in m. Taste in mouth as if she had eaten tallow ; all kinds of food appear to her bitter. In first upper molar, r. side, twitching pain as if one pulled something sharp in and out. In forenoon pain in same tooth for } h. j when she presses corresponding part of cheek opposite tooth with finger, it seems as if something cutting shot through root of tooth. Frequent micturition ; urine pale. Difficulty in breathing less than on previous days. Afternoon, on going out, chilliness over whole body (she is, however, not cold to touch) lasting an h. During the chilliness pulse seemed to her to beat quicker ; at same time ill-humour and indisposition to talk, even with her lover. She did not relish the beer she drank [only ^ pint). Loss of appetite ; fulness in belly, as if blown up, as if she had eaten and drunk a good deal ; lazy, weak, and sleepy. £., sees things as if through a veil. Pulse 92 at lO p.m. The last week in going upstairs palpitation of heart ; uneasiness in fi:et, she was obliged to move them constantly, on walking it was relieved. She went to bed early; slept, however, uneasily. 11 p.m., was awake with vertigo, nausea, weakness, trembling of limbs, and relaxation of all nerves. At 1 2 it drove her out of bed. In rising she became giddy as if she would fall, with inclination to vomit. She returned to bed again. In a few m. after, in bed, vertigo with unconsciousness and three times vomiting of food. What was vomited tasted like red wine (claret). After vomiting chilliness over whole body. She fell asleep about 2, dreamed much, and disputed and quarrelled in her dreams. 29th. — Awoke at 5 a.m. with pain in belly below ribs on 1. side, as if she would be loose in her bowels. At same time vertigo with nausea. The vertigo was relieved by lying higher. It returned on rising, particular! v on bending forwards, ft lasted, although relieved by applying cold bandages, through whole d. in afternoon it was su bad that she nearly tell trom

VOL. 111. 24 j

her scat. Loss of appetite ; no desire for coffee, but, on the contrary, for wine-soup ; emptiness In stomach ; obtuse patn in head whole d.j shooting pain in both halves of forehead directly above eyebrows. Forenoon, urging to stool ; stool with exertion, although it was quite normal ; much emission of flatus and frequent micturition ; urine daxk. Good appetite at dinner. Between 4 and 6 p.m. slight chilliness ; at same time itching on skin, especially in 1. breast, on head, arms, throat and thigh. On latter there came at times during d. sensation as if flesh were being scraped off" bones. Difliculty of breathing, especially great between 5 and 7 p.m., even when she kept quiet. Pulse appears to beat more rapidly. Weakness in hands and feet. At 7 she lay down in bed. She was awakened twice. In rising strong chill over whole body. When alone to-day, she felt as if she could always cry; she did not, however, know why. If anyone were with her, she was disposed to quarrel. Moreover she was ill-humoured the whole d. (particularly inc.), laconic, sensitive, and sleepy. 30th. — Awoke early. She felt giddy, even when in bed. The giddiness became worse after rising, but was relieved by applying cold bandages. Heat of head internally, especially in front ; no desire for coffee. When, in spite of this, she had drunk coffee, cutting pain on 1. side in region of spleen. Trembling in whole body, especially in hands and feet. In going upstairs feeling as if someone struck her in the bend of the knees. Trembling of knees when she puts her foot on a stair. (This trembling lasts whole d.). DifEcuhy of breathing whole d., aggravated by walking. Good appetite at dinner. Afternoon, so weak that she could not carry a basket of wood. Itching whole d. in both nostrils j paleness of face ; sorrowful humour. Latterly dislike to men. from 4.30 till 7 p.m. great chilliness, especially in warm room. When she went into open air she did not feel chilly. At 1 1 p.m. she was awakened out of sleep. On rising trembling of hands and feet ; she cannot hold anything steadily from weakness in hands. As she got into bed again a chill went through whole body (except head). At same time heat in head, and skin all over warm to touch. Soon after burning heat in hands, less in feet. It was an h. before she fell asleep again, was obliged to turn over and over in bed, and slept at last very uneasily with constant dreaming of quarrels and contentions. 3r5t..^M., in waking, pinching pain in belly, as if before looseness of the bowels. She had hunger, and coffee was agreeable. After a while contractive pain in belly with urging to stool ; hard and painful stool. Forenoon micturated 6 times ; urine pale. After dinner shooting pain in h half of forehead immediately above arch of eyebrows, lasting until c. About 6 p.m. when she looked at an object for a long time, particularly in sewing, it became suddenly dark before her eyes, and she saw nothing until she fixed the eyes on another object j at same time sleepiness. She went out. On returning home shooting pain in r, side below last ribs, with frequent yawning. When she goes into open air her checks become very red, so that people speak to her about it. At home she is pale. General weakness, yet less than usual, as is also the trembling of hands and feet ; cheerful humour. Uneasy sleep with much dreaming ; frequent waking ; she is obliged constantly to turn over and stretch herself.

■

1. Feb. 1st. — M., on waking, dulness in head j feeling of emptiness in stomach ; no desire for cofFee. After drinking coffee inclination to vomit. About lo a.m. immoderate appetite and longing for something very tasty. She received a letter containing unpleasant news. After reading it violent trembling in hands and feet. Strong appetite at noon. Afternoon after coffee feeling over whole body as if one poured boiling water over her, lasting lo m. ; thereupon burning heat in r, ear, whole of r. ear was scarlet red for J h. Towards 5 p.m. chilliness over whole body, only in warm room, at same time frequent yawning. If she went into open air she had no chilliness. In returning home between 6 and 7 p.m. shooting pain around navel. In r. side below ribs line shoots, continuing ^ h., then call to stool. During stool shooting pains around navel and in both hypochondria, aa if the parts were being screwed together; stool first hard then soft j feeling at same time as if the rectum had protruded; feeling as if stupefied after stool, with nausea ; soon after that vertigo ; everything turns round with her, and she almost loses her consciousness at the time. Sleep full of dreams of evil things. 2nd. — M., on rising, headache. In church yawning lasting ^ h., with shooting in r. side below last ribs ; dulness of head, inclination to vomit and empty eructations, with difficult respiration and trembling of hands and feet. In going upstairs difficulty of breathing ; palpitation of heart ; drawing pain internally in bones from thigh to ankle, most violent from knee downwards. It seems to her at the time as if someone would pull her backwards in ascending. After breakfasting off coffee, cutting pain, with audible grumbling and rumbling in belly, particularly at rest. During d. fine shoots in different parts of integument, especially on chest, scrobiculus cordis, both wrists and thigh. Good-humoured whole d. In e. heaviness and uneasiness in legs, which increases after drinking moderately of beer. (Before the appearance of the catamenia, which arc due on the 9th, she always suffers from heaviness and uneasiness in the legs.) Before going to bed vertigo with inclination to vomit and trembling of whole body; pressive pain in forehead; heaviness of upper eyelids. She was awakened about 12 o'clock. In rising dulness of head, as if stupid ; stomach as if too full ; at same time feeling of weakness and trembling in stomach ; dryness in mouth ; trembling of fingers ; she cannot hold anything fast in the hand, or even close it, for weakness. 3rd. — Awakened about 4.30 a.m., in rising shooting pain in the shoulder-joint, and from mastoid process of r. temporal bone as far as anterior part of the throat, lasting i h.. Increased by motion ; at same time constrictive pain in stomach, then cutting and rumbling in belly. Ill-humoured in forenoon ; sleepy in afternoon ; chilUness in back. 4th. — M., in church, empty eructations ; frequent yawning ; shooting in scrobiculus cordis ; pressive pain in stomach, as if something heavy lay in stomach, with trembling of hands and feet; difficulty of breathing, even when she keeps herself quiet. In going upstairs palpitation ofthe heart. Afternoon, she could not bear to be anywhere. She was sorrowful, as if mortified. Between 4 and 7 p.m. in warm room chilliness in whole body ; she felt warm to touch, only not in face. Repugnance to beer and wine, although she was

37»

thirsty; beer had a watery insipid Caste. In going home heat in head, with redness of face and ebullition of blood to head ; cutting pain around navel, which ceased after pressing on belly, throughout whole d. ; stool hard and dry; sulicy, pensive j dulncss of head. (Since she commenced the proving the head has never been free from pain.) Sth. — Frequent micturition throughout d. ; after urinating each time burning in vagina, as if it were raw, lasting a short ^ h. \ urine turbid, yellowish red ; shooting pains from r. lumbar region downwards towards uterus, more violent and constant in forenoon, frequently intermittent in afternoon ; insufficient stool ; lazy and quarrelsome. 6th, — M., shooting from region of kidneys towards uterus, ameliorated by sitting bent forwards, pressing on belly, or sitting down, increased by walking. Whilst drinking coffee grumbling in belly. After coffee above pain ceased, but returned from 9 till 11.30 a.m., and again, more violently than before, after dinner. Urine scanty ; ill-humoured. 7tb. —In m. in bed menses appear more profusely than usual ; blood darker ; vertigo in stooping. Boring pain in umbilical region, and violent palpitation of the heart throughout d. Feeling of weakness in whole body. Urine scanty, acrid, corrosive, dark, like brown beer, deposits a red sediment which adheres to the vessel. Sth. — Menses as profuse as yesterday. Great restlessness during sleep, with frequent dreams which she cannot recollect, and frequent waking. She is generally restless in n. during catamcnial flow, though not so much so as now. After cofiee pinching in belly i desire for sweet mucilaginous things (otherwise at that time always for beer, which to-day is repugnant to her). 9th. — Restless sleep full of dreams ; she dreamed that she pulled a very fine tooth out of her mouth. Menses as yesterday. After coffee, loud grumbling in belly. Forenoon, nausea, so that she believes herself scarcely able to sit up. Prcssive headache now in r. now in 1. half of forehead. After dinner trembling and twitching of I. upper eyelid. Feeling as if flesh were being scraped or torn off bone from below upwards, beginning from lower Jaw, over zygoma to r. temple, lasting about 10 m., returning every 5 m., and always becoming more violent from 4 till 7 p.m. Much thirst, particularly for beer ; trembling of hands ; frequent micturition ; urine pale, not acrid ; menses less profuse than in forenoon, loth. — M., menses have ceased. Throughout d, extremely sensitive and peevish. In e. after violent vexation reappearance of catamcnia. 1 1 th. — M. and forenoon, dulness of head. Throughout whole d, and also in n. frequent micturition. The catamcnia have again ceased to flow. 12th. — In m. urine milky, as if milk had been added, later with white sediment. After going out^ still more on returning home, shooting pain now in r. now in 1. side of forehead. Cutting pain as if with a sharp knife from 1. half of forehead to occiput; weak dim eyes; little appetite ; taste bitter ; cutting pains in bowels, slightly intermittent ; two loose stools ; shooting in scrobiculus cordis ; cold and hot flushes over body ; trembling in whole body; general weakness; difficulty of breathing in walking, and in going upstairs also palpitation of the heart. All these phenomena lasted whole d., and alternated frequently one with another. Towards noon she became so sick that she was obliged to lie down in bed. In

£illi

deep twitching in limbs as if sh<

electrified. If shi

P

k

twitcning in iimos as u sne were dosed eyes she saw many people, large cities, great waters pass before her. After rising she did not improve, pulse quick and full. In e. it was long before she could fall asleep. When she tried to sleep she was seized with twitching in limbs and electric shoclcs of whole body. Once it appeared to her as if her knees and chin would be knocked together. Slept well after midnight. 13th. — In m., after rising, pinching in belly ; fine shooting in forehead ; trembling of hands. Subsequently there showed itself for an h. slight leucorrhoea ; loathing of animal food; even bread is not relished. After dinner shooting pain first in r. then in 1. half of forehead, lasting for hours. Towards 4 p.m., after she had drunk a very little coffee, nausea, inclination to vomit with empty eructations ; trembling of stomach j yawning for 1} h. ; internal chilliness during which she was quite pale. Pulse very quick and intermittent. Also the headache became at this time more violent, and if she took hold of her forehead she had the feeling as if there was a hammering in head. Difficulty of breathing ; tearing pain in spinal column from above downwards j during whole d. frequent urination; urine turbid. 14th. — Headache; Icucorrhoea, a few times in d, ; tearing in different teeth, now in r. upper, now in I. lower jaw; tearing pain in spinal column whole d. She could not for a long time fall asleep on account of pains in back; sleep was restless. 15th. — In forenoon shooting in chest from xiphoid cartilage of sternum through to back, worse afternoon ; loss of appetite ; much thirst ; shooting in r, side of cavity of chest, during which she was obliged to sit with knees up to stomach, increased by walking. No pain in taking a deep breath. After midnight sleeplessness. i6th. — In m. two loose stools without pain ; shooting pain in temples. In afternoon it appeared to her as if there were a gauze before eyes. She could scarcely see to knit. Heaviness of the legs. 17th. — In m. during breakfast (coffee) screwing cutting pain in belly with grumbling. Latterly remarkable forgetfulness. {IhiJ.)

1. Dr. ScHWARZ made repeated experiments with the 1st trit. and with salt in substance.* The trit. showed sometimes none, sometimes only a slight and transient action. Pinching, grumbling in belly, sleepiness with frequent yawning, heaviness and weakness of limbs, indifferent or sorrowful state of mind, indolent hard evacuations, frequent micturition without having drunk much, — were constant symptoms. More transient and only sometimes present were sensitiveness of scalp, heaviness in head, stitches through head into nape of neck and chest, roaring in ears, heartburn, eructations, unusual hunger alternately with loss of appetite, sensitiveness of teeth, vesicles on tongue,

• SCHW— took: (a) From March ^rd— 14th, 184 J, daily 5 gr. isttrit (i : 100) j (b) »me dose daily from March 13rd till April ist ; (f) From April «nd till May i»t of »amc trit daily 10 gr. ; (^ Jurt as many gr. of xst tnt. (jo : 90) daily firom Oct, 6th— 19th i (t) Oct. 34ih I, asth a scrupltt i a6th 1, 17th i^, aSth a, »9th 3, 3olh 4, Nov. i!»t, 6 drachms of cnidc salt ; (J) from Nov. 6th— i jth, 5, lo, 1^ 30, and 110 gr. of lit trit. (10 1 90). daily, every ind d., or every 3rd d. j (g) From Nov. 13rd— jolh and from Dec. ath— 14th, the same i« tnt., beginnmg with 10 gr. daily, iocrcaiing by 10 gr., and from Dec. i4tli onwards dimimihing in same way

back again to to gr.

$74

distraction, irritability, starting of limbs, particularly of muscJes of

thigh. Salt in substance excited : — Scraping in throat, very violent thirst, loathing, loss of appetite, much eructation of tasteless and odourless gas. All these symptoms, however, disappeared always a few h. after taking it. (UU,)

i6. Schwarz induced a weakly woman 7 months advanced in pregnancy, between 20 and 30 years of age, to prove common salt. She noticed after 10 gr. of ist trit. under a strictly regulated mode of living the following symptoms : — The sleep, otherwise usually interrupted by frightful dreams, particularly during the first 3 d, sound and composed ; after a previous disposition to constipation, a regular easy stool daily ; thirst, which had formerly been quite absent j sorrowfulness, tearfulness without cause; prostration, weakness, trembling ot limbs ; sensitiveness of body to contact ; sweat induced by least exertion. Besides these, dulness of head, pain in temporal region ; burning in eyes with increased secretion of mucus ; eyelids adhere together in m. i great sensitiveness to light of lamp ; violent roaring in ears ; spas, modic constriction on chest, very troublesome in taking deep breath ; stitches in abdomen i cutting in belly, relieved by emission of flatus j grumbling and rumbling in bowels ; very frequent micturition. (As the last symptom continued long after the other symptoms had quite disappeared, Schw^ ascribes it to the pressure of the uterus on the bladder.) (/A/V.)

1. Dr. Wachtgl describes a series of four provings of salt. Feb, 2ist, 1843, I took, carl^ in m., 10 gr. 1st trit. (10 : 90).

Towards

No symptoms, 22nd. — 10 gr. 1 o wards 11 a.m. nnging m ears, which continued whole d., and only at intervals alternated with feeling as if air were blowing into 1. ear. In e. heaviness of lower extremities. 23rd. — to gr. The roaring and ringing in ears continues. At noon during dinner, pulsation in scrobiculus cordis, which lasted some m. In afternoon in walking, cramp-like pressive pain on r. shin-bone near ankle. It seemed to me as if the drawers were too tightly tied at this part. On sole of I. foot towards middle toe there appeared a white spot about the size of a sixpence, not elevated above the surrounding skin, very painful in walking. In e. swelling of lower extremities from halfway up the leg down wards,with feeling as if the feet were loaded with lead. 24th. — 10 gr. The feeling of heaviness in lower extremities continues ; the pain in r. foot extended further upwards towards middle of tibia. Inn. itching in 1, leg, obliging him to scratch. 2Sth. — 10 gr. The pain in r. tibia has considerably diminished, but there came on in walking a feeling as if in one spot the bone were loosened, so that I commenced to walk with anxiety. In afternoon itching in r. palm. In e. dull pain as if bruised in r. zygoma and in coccyx, causing feeling on being touched as if he had fallen on that part ; the former pain soon went away, the latter continued whole d. In e. the white spot above described had almost disappeared, but further forwards a vesicle the size of a pea had formed, which discharged bloody serum. 26th and lyth. — I took no med. and perceived beyond a burning in urinating nothing worthy of notice. After 10 gr., which I took 28th and on Mar, 1st, I felt, parricularly in getting out of bed, very tired and pros-

tratc. On 2nd to 7th March I took no mcd. The syoipcoms which appeared during those d. may be summed up as follows ;— Constrictive pain in stomach ; feeling of heat in rectum ; colicky urging to stool ; chills down back ; prostration of limbs ; vivid pleasant dreams, so that I could recollect after waking perfectly connected conversations. On 8th, early in m., 10 gr. Soon after, frequent sneezing, shooting in uvula. About 11 a.m., pain in I. half of head, which extended into eyeball and produced feeling as if a nerve were tightened and suddenly relaxed again (a kind of springing pain). Before dinner constrictive and cutting pain in stomach, lasting several m. and frequently returning, which terminated in e. with feeling of pressure, 9th. — 10 gr. The pain in stomach previously described appeared again towards noon, but lasted only a short time. In e., itching in hair on pubes ; slight swelling of inguinal glands; pressivepain in r. testicle; urging to stool, but without result. Very restless n. On loth to 14th took no med., and could note nothing particular excepting hard evacuations and uneasy nights. I5^h. — 10 gr. In course of forenoon there appeared dulncss of head and prcssive pain in temples, which was twice interrupted, but only for a moment, by springing pain in 1. half of head. After dinner these symptoms disappeared ; on the other hand, I was seized by a very painful rhythmical pulsation, shooting, lasting a few m., in one of the cervical muscles on r. side. Quiet n,, dreams vivid. i6th. — No med., and so also on S following d. The pain described above appeared to-day, yet in a slighter degree, in deltoid near its point of insertion into arm. In afternoon frequent emission of Rhus per anum. In e. there appeared a regular pulsating shooting in glans, with transient solitary fine stitches in orifice of urethra. There flowed probably also a drop of sticky mucus from urethra, as I found the shirt stuck together. Sleep tolerably quiet excepting being awakened 3 times, when I perceived feeling in rectum as if I had taken cold, with involuntary emission of asmall quantity of slimy fluid, 17th. — In forenoon, with exception of feeling of coldness and emptiness in stomachy nothing particular to relate. Directly after (a plain) dinner I noticed a considerable disten- Kton of abdomen, violent constriction of stomach, call to stool, yet without result, and after frequent ineffectual efforts 7 to 8 thin fluid evacuations with colic. Thereupon all pains ceased, and I felt again quite well. Quiet n., vivid but not pleasant dreams. i8th. — Prostration in limbs ; rumbling in abdomen ; feeling of coldness in stomach, and 4.diarrhoeic painless stools. In e. distension of the abdomen ; painf\ii sensibility of whole linca alba ; distended navel, sensitive to the touch. Restless n. 19th. — The whole forenoon remarkable weakness of body ; heat of head with roaring in cars ; oppression of chest and shortness of breath ; feeling of coldness and emptiness in stomach ; 3 thin fluid evacuations ; loss of appetite. Afternoon, extraordinary sleepiness, so that in the moment of sitting down I already began to slumber. About 6 p.m., frequent chills, followed by heat and sweat, which lasted until 7.30 p.m. 20th and 21st. — The thin fluid stools continue. Vibration in muscles of back, r. arm, and calves. Restless nights. 22nd. — 10 gr. After dinner distension of abdomen with emission of flatus. Towards 5 p.m. colicky urging to stool, without result ; pres-

sive feeling in stomach. About 7 p.m. 3 evacuations rapidly following one another, without relief. The whole n. feeling of soreness in bowels y constant waking out ot very vivid unpleasant dreams. 23rd. — Flying stitches in r. Icnec-joint ; drawing pinching pain in 1. carpal joint, increased by contact, diminished by heat. No evacuation. Quiet n. Up to the end of the month, the flying stitches in joints, u well in upper as lower extremities, frequently appeared. The abovementioned pinching and drawing patn in 1. carpus continued incessantly for several d. On the 5th d. for the first time occurred evacuation, with straining and chills. The costivcness lasted for 3 weeks.

b. My second proving with pure salt, of which I took, April 19th and every succeeding d. up to 30th, 5 gr. dissolved in half a glass of water, furnished but a thin harvest. The phenomena subsequently observed were the following : — Shooting and tearing in shoulder and knee-joint ; beating in pit of stomach, particularly after a meal ; pinching pain in 1. forearm ; in region of navel sensation as if abdominal wall were pressed upon by a solid body from within outwards ; costive* ncss i restless nights with vivid dreams.

(. After more than 5 mos. I commenced my third proving with 10 gr. of 1st trit (10: 90). Symptoms: In m. great hawking up of mucus ; in urinating flying stitches in bladder, which after complete evacuation of the urine disappeared again j towards noon startingshooting in muscles of 1. arm, in region of elbow, lasting 10 — 15 m. and returning in afternoon. Aftcrdinnerdistcnsion of abdomen, with frequent emission of flatus ; a mucous evacuation, with straining and burning in anus. In e. repugnance to beer and tobacco. In n, flying chilk in sacral region, and involuntary emission of a few drops of slimy fluid from anus, nth — 14th. — No symptoms, with exception of thin fluid mucous stools, and nights full of dreams. On the 15th, 10 gr. Feeling of heaviness in lower extremities as if after a long tour on foot j frequent sneezing, In afternoon sudden call to urinate, with emission of a considerable quantity of pale urine. This urging was repeated 3 times at short intervals, whereon much urine always followed. In c. violent stitches in 1. instep, as if with a red-hot needle. Two slimy evacuations. j6th, t7th, and iSth, daily 10 gr. Except heaviness in legs no medicinal action. On 1 9th, external meatus of 1 . ear was swollen and painful to contact. On following d. these morbid phenomena remained unchanged. 21st, — Pressive pain in root of nose j great flow of mucus, with occasional stoppage of 1. nostril. In e. on 1. tibia pressive pain, as if a band were bound round it too tightly. On 22nd and 23rd no medicinal action. On 24th, 10 er. In course of forenoon four tenacious mucous stools. In n. tearmg and drawing pains in wrists and ankles, so that I was aroused out of sleep. Although perfectly awake, yet I could open the eyes only with effort. On 25th, 26th, and 27th, no symptoms. On 28th, 10 gr. Appearance of a vesicle the size of a pea filled with bloody serum on nape of neck near hairy scalp. Four diarrhccic stools. On 30th the vesicle had dried up, and there remained only a scab. Although I took no more medicine, yet phenomena appeared up to Nov, 15th which I was obliged to ascribe to the action of salt ; tickling cough, with hawking up of mucus, especially in

natrum muriaticum.

m., long-lasting swelling of glands on I. side of neck ; irregular evacuations, so that for several d. I had 2 to 3 stools daily, then afterwards suffered from constipation. One constant symptom 1 noticed, namely, frequent urging to stool, but without result; besides occasional appearance of drawing and paralytic pains in almost al! joints, easily tired and inclined to sweat.

d. On Nov. i8th I took \ oz. of salt dissolved in a glass of water. About 3 p.m. violent pressive pain in sternum, along with sensation as if that place had been struck. This feeling was not increased by taking a deep breath, but certainly was by contact, and also by movement in open air. Towards e. it totally disappeared, but returned next m. and lasted till e. of 20th. On 21st I swallowed, an h. after breakfast, a whole ounce dissolved in water. Soon after, accumulation of saliva in mouth, with inclination to vomit; feeling of chilliness in whole body, with heat of forehead and pressure near root of nose ; great thirst. In e, itching and smarting on lower extremities, as after a mustard bath. J I p.m., 5 or 6 violent shoots rapidly after each other in breast, crossing one another from without inwards, with oppression of breathing. Next m. on awaking paralytic pain, extending from nape of neck over shoulder as ^r as middle of arm, and continuing with short remissions till c. Extraordinary weakness of upper part of body, less in legs. In n. in urinating burning along whole of urethra, as after new not properly fermented beer, 22nd. — Pressive pain in sacrum, with desire to assume the erect posture. Towards c. in open air twitching pain in 1. temporal bone, which extended towards external canthus and ultimately spread over eyeball. Later, pressive pain in K knee-joint, rendering walking difficult. On 23rd and 34th no phenomena worthy of remark. 2$th. — I took in afternoon again \ oz. I noticed afterwards the following phenomena : — Pressure in region of stomach and forehead ; pulsation in scrobiculus cordis ; slight drawing in 1. fibula. Frequent waking in n. On 26th, in afternoon, slight chilliness, and in e. burning heat in hands. 27th. — In course of forenoon twice shooting in region of spleen, increased by walking. 28th. — In e. twitching-tcaring m I. eyeball ; in abdomen feeling of burning, increased by pressure. 29th. — Thumb of 1. hand feels as if sprained, and often paralytic drawing with simultaneous obtuse shoots in os coccygis. In e. heat of head^ with subsequent sweat. In n. feeling of burning in vertex ; restless sleep. 30th, and Dec. 1st and 2nd. — No remarkable symptoms. 3rd. — In afternoon dulness of head, with great pressure in temporal bones and root of nose ; sensation also as o? reeling in brain, with fits of urging towards forehead, continuing till e. In n. these symptoms somewhat relaxed ; returned^ however, next d, with renewed violence. 5th. — I felt for a few h. tn forenoon quite well, yet about ii the sensation of reeling and urging in brain towards front commenced so violently whilst I was walking down some steps that I was obliged to hold on by the handrail ; at same time lower limbs trembled, and there was feeling as if feet were swollen and without sensation. This condition went off almost totally in \ h., but returned about 3 and 5 p.m., although in less degree. In e., after previous feeling of anxiety, heat in whole body and sweat, which lasted x ) h. 6th. — Drawing pains in

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joints. At 6 p.m. again anxiety, with heat in head ^ afterwards great sweat. 7th. — Sweat recurred in e. at same h. 8th, 9th, and loih. — No symptoms. Involuntary emission of a small quantity of urine. This symptom was repeated also on 13th in walking. Up to end of January of the next year morbid phenomena appeared, which I must ascribe to the action of salt. To these I add : prostration of whole body; easy inclination to sweat ; constipation, and restless nights full of dreams. {Ibid.)

1. Dr. Wagner conHned his provings exclusively to ist and 2nd trits. After 2 gr. of 2nd, which he took March 7th, 1844, about 9 p.m. after having fasted since dinner, he dreamed after midnight of offensive things (especially of diseases) and slept uninterruptedly. Next ra. his head was dull, heavy, dizzy i he felt pressure in forehead, in temples pressing from within outwards. A sensation of heaviness and fatigue extended itself along posterior surface of thigh downwards towards bend of knee. At same time unusual urging to urinate, and on protracted retention of urine troublesome drawing along ureters and feeling of pressure and heaviness in 1. side of forehead. On following e. at (o Wg — took 5 gr, of same trit. Next m. dulness of head and weakness oflower limbs, especially of knee-joints. These symptoms disappeared, however, towards noon. After taking 10 gr. of 1st trit.^ on i ith and 1 2th, no indications showed themselves excepting increased urging to urinate. Wg — now returned again to the small doses, and took on 13th 2 gr. of 2nd. The following n. he dreamt vividly and remembered them accurately next m. (which was unusual with him). Throughout d. limbs were prostrated, chest heavy and oppressed ; sometimes slight stitches darted out of depth of chest cowards back (particularly in taking deep breath). For a few h. of the forenoon unpleasant pressure in scrobiculus cordis. When Wg — had rested five weeks he began a fresh experiment 20th April at 10 p.m. with 5 gr. of 2nd trit. During n. and on following m. he remarked besides increased urging to urinate no phenomena. In forenoon whilst walking transient stitches, running deep through 1. half of forehead, spreading towards temple and ear, alternately with pressure and feeling of heaviness above orbital cavities. A few times peculiar pressure on posterior wall of larynx and pharynx, running along Eustachian tube and towards tonsils. Towards e. there gradually formed itself a pain in face which occupied whole of 1. side, particularly region of eyes, nose, and temple. Wg — closed his proving next e. (aisi) with 10 gr. of same trit. Thereupon, about \ h. after he was seized with peculiar feeling of heat, which spread itself from stomach at iirst over chest, later towards abdomen, but fixed itself particularly in region of navel. Besides this Hying stitches, and fulness and heaviness in r. hypochondrium ; rumbling and feeling as of air-bubbles which ascend and burst in intestines j increased urging to urinate^ with very clear limpid urine. After midnight he awoke with considerable pressivc pain in L half of forehead \ subsequently profound sleep full of dreams. The following d. unusual prostration, especially felt in thighs, arms, and shoulder-joints ; periodical pressive shooting in brain. The whole of the above symptoms were relieved by walking. (Wg^ —

f

the character he has slcctchcd of himseJf, is upwards of 29 years old, nervous venous constitution, with prominent bilious disposition, rigid fibre, strong muscular system ; for the most part healthy, deducting the diseases of children, up to the period of adolescence, subjected in later years especially to diseases of the nervous system (aifections of the liver with great sensibility and easy excitability of the nervous system). Hardened in his youth) he is not easily affected by physical influences, whilst moral ones act rapidly and continuously upon him. A chill, for instance, never induces a cough in him, but vexation very soon, and the cough bears then generally a violently spasmodic character. Further, he has the peculiarity of being affected in a scarcely noticeable degree by powerful drugs, even poisons, with which he made formerly some experiments, whilst he offers a not inconsiderable impressionability to small doses of medicine, such as the homoeopathic potencies. He has also a particular idiosyncrasy towards various things, for instance, strawberries, which always produce an eruption and nausea in him.) (/W.)

1. Dr. Watzice made 7 provings with salt.

a. The first I began on March 2nd, 1843, at noon fasting with 12 globules of 30th attenuation (prepared according to Hahnemann's directions). 5 h. later, as well as the following d. {3rd), I took early in m. and in e., 20 of such globules. I repeated same dose fasting early on m. of 4th. During these 3 d. 1 observed the most rigid homceopachicdiet. On the 3rd, afternoon, I noticed, as I walked over a stone bridge, a very transient fit of giddiness. It was as if the stones beneath my feet were sinking down. On same d. a few h. later, I was seized, while walking in the street, with some long stitches in r. knee (which came and went slowly), i had, moreover, during these 3 d., each d. a few small more watery than pappy evacuations. I am, however, not inclined to bring these phenomena in causal connection with the medicine exhibited, because they bear a stamp foreign to that of salt, and may be explained partly — the vertigo and the stitches in the knee — as the result of the intense observation paid to myself, partly — the evacuations — as the consequence of the unusual mode of living induced by the strict regimen. On the 9th I took at 4 and 8 p.m. each time a teaspoonful of the 3X tnt. 1 repeated same dose following 4. m. and e. No trace of any medicinal action whatever appeared thereafter. Just as fruitless in results was the third experiment, with 5 dr. of the zist dil. taken on m. of nth. On the 13th, 8 a.m., I took 3 drachms of crystallized salt, dissolved in a tumbler of water. I repeated the dose on 14th at 8 a.m. and at 3 p.m. On the 13th and 14th, in forenoon no other phenomena showed themselves besides increased thirst and somewhat more frequent micturition. On the 14th in e. a fluid evacuation without straining and pain in belly occurred. 15th. — Feeling of roughness in throat, not lasting long ; in m. and after dinner two small fluid evacuations, also without straining or pain in belly ; after the stools smarting in anus, which continued whole afternoon. Pressive pain in vertex, which likewise occurred after dinner, must not be ascribed to the salt, as I am frequently affected in a like manner after a disturbed n» and continued exertion of the brain.

3^0

The t6th and ryth I took each m. a teaspoonful of the 6th trit.* I perceived afterwards no trace of any drug symptoms. The same result followed after 1 had talcen on j8th, i9th, and 23rd on each occasion a teaspoonful of the 5th trit. Also after 3 teaspoonfuls of the same trit., 24th,, e., no indications of medicinal action were present. On the 1st April at noon, shortly before dinner, I took 3 drachms of salt dissolved in a glass of water. Soon after dinner, preceded by borborygmi, two watery stools quickly succeeding each other, without straining and almost without griping in belly. When out walking shortly after that painless pressing outwards (lasting 5 m.) occurred in middle of belly a few fingers' breadth to r. of navel, resembling that which pregnant females complain of sometimes, as if some part of the foetus pushed against the place. Also, whole abdomen was extraordinarily ten»c and distended. In riding in a carriage I was seized with frequent painful stitches in 1. thigh. In e. of same d., sensitiveness of external wall of chest, great prostration, indolence of mind, unconquerable sleepiness. 1 was, contrary to custom, at 10 p.m. no longer able to read. In lying in bed considerable painfulness of spinal column, which was increased when I lay on my back. On following m. about 4 o'clock, in driving, a few stitches in 1. maxillary joint. On same d. (2nd) I took at 8 a.in. I drachm of common salt in half a glass of water. In afternoon, on walking, tensive pain in r. popliteal space, as if tendons were too short, lasting several m., almost obliging me to limp ; thereon on sitting suddenly a few very sensitive stitches in r. great toe. On 3rd, early in m., again 3J. In course of forenoon frequent violent stitches from back and partly from chest towards middle of arm, as if produced by drawing sparks from an elcctrophorus. In e. troublesome distension of abdomen, which occurred also, though in a less degree, on previous e. Restless n,, full of vivid exciting dreams, with frequent tossing in bed. On 4th, 9 a.m., again 5J. In forenoon faintness, slight pressure in stomach, tension in abdomen as if I had eaten too much, threatening of retching in throat, inclination to vomit. On same d., | h. after dinner, another drachm. In afternoon, a scanty fluid evacuation with some straining ; in e. tension in inguinal region. At bedtime (lO p.m.] again 3J. 5th and 6th.-— I took each m. y] ; on 7th, shortly before dinner, ^iij. With exception of slight tension in bowels and a few loose stools no symptoms showed themselves during these 3 d. On 8th, 11 a.m., I again took ^iij in a glass of water, this time, however, with almost invincible loathing. Immediately thereon, inclination to vomit, with eructations of air and some accumulation of water in mouth. The inclination to vomit continued ^ h., and it was only with effort that I could keep from vomiting. It was better after a plateful of clear soup. Thereon, commotion, gurgling, rumbling, and griping in belly, hasty call to stool^and an evacuation, which during the several m. that it required, brought away a great quantity of a thin, fluid, almost watery, stuf^', with noisy violence and great flatulence. An h. later there followed a similar, only shorter and lesa violent stool, with

• I purposely interrupted the experiroent with the unsuccessful dilutions by interpolating instead the raw roaterial, in order to ascertain whether it were pos&ible to create a sensibility to the smaller doKs by means of previous large ones.

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burning in anus ; it returned to a slight extent once more 4 h. after. No other phenomena showed themselves. On 9th, 8 a.m., I tried again 3J. In afternoon I was seized in I. calf and 1. natis with sensation as if I had fallen on those parts. On following d., on which no mcd. had been taken, there occurred tension in the bend of r. elbow, as if arm had been exerted too much. April I5thj i6th, and 17th, each d. 5J. The first drachm created (an h. after) urging to stool accom* panied by slight griping and commotion in belly and almost fluid evacuation. The other 2 drachms caused no more looseness.

b. The phenomena developed in me during the proving by common salt led me to believe that its action upon me is just as transient as superficial. I deceived myself, however. It proved to be more permanent and powerful than I wished.* Soon after my last proving there appeared remarkable weakness and prostration of the body. I was not able to make my usual rounds in the suburbs on foot. The painful tension, already noticed in the former experiments, here and there in the joints as if the tendons were too short, or as if I had been struck there, occurred now more frequently. The tensive pain in the groin and popliteal space was sometimes so great that in walking in the street it was with trouble that I could get on for a few m. The irregularity in respect to the time and repetition, and with regard to the quality of the evacuations, which I observed during the whole course of my proving (with the larger quantities), continued far into May. I had, namely, now no evacuation, now only one in the d., now two, three, even four. These were sometimes soft, sometimes quite fluid, sometimes hard. Frequently they were followed by smarting in anus. At same time I had continuously rather a small appetite, no quiet sleep, very vivid connected dreams, looked badly, got much thinner and was unusually depressed. The indifFerence to the absence of salt in my food showed itself in a strongly pronounced manner long and continuously. For some weelcs my food could scarcely contain too little salt. Strongly salted things suited me remarkably ill. A very small portion of salted herring which I ate one e. resulted in commotion in the bowels, distension, loss of appetite, and a very uneasy sleep interrupted by frequent drinking. Towards middle of the month of May a peculiar very troublesome periodical affection of the urethra and rectum developed itself, for which 1 knew no other cause than the considerable quantity of salt which I had taken. There occurred frequently during the d., though irregularly, often several times in an h., often at intervals of 5

• My proving of common salt docs not fiiraibh exactly a particular support to the hypothtrsb that a medicine requim another special impressionability (diiipo^ition) than that of general human frailtVi in order to unfold it^ actions on the organism. At the same time it provided me with the key to the secret how to become drug-diseascd. It could not be easy for anyone to show themselves teu susceptible to small as well ajv large doses of common salt than I showed myself at the beginning of my experiments. The small doses made none or almost no particular impression ; the larger were ejected by the org:iniftm in the shortest way and in all

Sossible ha&te. And yet the medium doses, used continuously for a longer period, evetoped the ult|discaAc in me almost to complete cachexia ^ and of all the medicines which I have hitherto proved, none created ultimately such a deep penetrating tenacious action in mc as common salt.

38»

and 10 m., often only im 2, 3,4 h., sensitiveness of urethra not increased by external pressure, contractive pain in the part and in rectum, with urging to urinate and to stool. The urine was clear, in sufficient quantity, and passed without pain. After micturating, as a rule, the urging to stool disappeared. The latter could in general be suppressed, but still threatened several times in the course of the d. The stool was soft, more fluid, without previous griping, not accompanied or followed by straining ; moreover there was no kind of discharge from the urethra and no affection of the sexual organs present. The affection just described disappeared completely by the end of May with the use of colocynthin. Whether the sensibility and swelling of the testicles which appeared subsequently from June 7th to lOth, and the tension in the inguinal region connected therewith — ^this tension was aggravated by movement and was accompanied with stitches from sacrum towards groin — whether these symptoms be further effects of salt I will not take upon me to decide positively. {Ibid.)

1. Dr. F. C. Weinke undertook three experiments. He has furnished the following report thereon.

a. ix trit., March 4th to 8th. Every d. in forenoon 10 er., without any noticeable effects. loth. — 20 gr. Half an h. after dull pressure in 1. half of thorax, which ceased after walking for \h. 3 p.m., a few dull stitches in r. half of chest. At n. (afrer much walking) considerable cough with scraping sensation in chest in m. isth and 13th.— 20 gr. No particular effect except weariness and ill-humour (perhaps ascribable to the annoyances incidental to our profession).

b. 6th dil., April 1 2th, 9 a.m., 6 dr. without water. Hereupon dryness of mouth, particularly of tongue, lasting more than ^ h. 13th.— Same dose. Weariness and flatulence throughout whole d. 14th.— Awoke in m. in very bad humour, which became angry irritability. The latter disappeared at the commencement of my visiting. At 7 p.m. prickling pain and feeling of coldness in scrobiculus cordis, from which srirches extended backwards and up into chest. Half an h. later (whilst walking) prickling feeling in under surface of 2nd toe of r, foot, 10 p.m. (after having taken wine), very violent sneezing followed by shaking dry cough. A good sleep { h. after. 15th. — 6 a.m., 10 dr. At I p.m. on inner side of 1. knee, stitches from within outwards as if a fine nail had been driven in there. i6th.-^ a.m., 10 At. Shortlr after transient pressure in 1. half of chest. 18th.' — 7 p.m., 10 dr. Hereon considerable dryness of touguefor ^ h. At 2 a.m. awoke in perspiration and with feeling of painful anxiety as if I were enclosed in a deep dark cellar, which feeling first disappeared when I perceived the first streak of light through my window. Hereafter sound sleep. 26th. — 11.30 a.m., 20 dr. Half an h. after while smoking tobacco, gnawing feeling in a carious tooth in 1. lower jaw. At same time feeling of sinking in stomach and several times empty eructations. In spite of this had excellent appetite at dinner. Afternoon, unusual cheerfulness i heart -elevating consciousness of physical and mental power \ unmitigated assiduity during very far excursions in the most unremunerttive parish practice. 7 p.m., whilst walking, at each time of raising I. foot yery sensitive, pre&sive shooting, at same time convul-

sive pain from Icnee upwards along axis of thigh. This pain disappeared after about 3 m. further walking. Later an extraordinary longing for wine, increased still more by partaking of Italian sasuage. After drinking half a measure of wine excellent sleep. 28th. — 1 1 a.m., 20 dr. without water. After 7 p.m., in walking electric shock from r. hipjoint downwards and inwards. 29th. — At n, verj' vivid dream of burning thirst which was not quenched by beer drunk wholesale (of course only in the dream). On awaking dry tongue.

r. Dec. 6th. — 10.30 a.m., 3 drachms of salt in a glass of water. Directly after, burning in stomach, and at same time shivering in periphery of body; feeling of sinking in stomach; constant spitting. Half an h. after shivering in a well-heated room. An h. after that diarrhocic stool, followed by inodorous eructations, which disappeared some time after, but which again returned during dinner. The appetite, hitherto excellent, considerably diminished. 2 p.m., a second fluid evacuation. 3, after partaking of black coffee, giddy fulness of head, which continued j h, 5, I drachm in water, without any effect except laintness in stomach. 7th. — 10.30 a.m., 2 drachms in water, soon after which coolness and slight pinching in belly, flatulence, indisposition to naental exertion, sleepiness. In an h. a sufiicient evacuation, partly watery, partly pappy. At noon tolerable appetite. About 2 p.m. a small fluid evacuation. At 5.30 ^ drachms in 2 tumblerfuls of water, which dose was borne remarkably easier. No other effect than very confused yet vivid dreams in n., whose chief content was the proving. At 3 a.m. awoke quite lively, which has not happened to me for years. Towards 3 I fell asleep again, and was only with trouble awakened about 7.30. nth. — Ac 9.30 a.m. J oz. in a tumblerfulot water. Immediately thereon feeling of coldness and pressure in stomach ; general coldness ; Inclination to vomit. An h. after tolerably copious, fluid, dark-brown evacuations. At ix.30 a.m. a second copious watery stool, coming away tumultuously ; immediately after it a strong erection, without any sexual provocation. — At noon tolerable appetite. At 2.30 p.m. a third watery copious stool. At n. a very vivid long dream (correctly remembered next m.), respecting a dangerous journey by water in a small boat. During the whole time of the proving with large quantities of salt I noticed a frequent easy expectoration of grey, globular, compact mucus, {/hi^.)

1. Dr. J. N. Wdrstl, a;t. 40, sanguinco-choleric temperament, strong constitution, troubled frequently in early life^ particularly after a chill in the feet, with gouty-rheumatic affections of the extremities and diarrhoea, but at time of proving perfectly well. He undertook four experiments, and exclusively with the dilutions. His report 6A' the results of the same is literally 2s follows :

a, March 2nd, 1843, at 9 a.m., 5 dr. of 9th dil. In f h. aftjer taking it, I noticed in region of stomach, for about breadth of hand, a pressure, which continued almost ) h. and again disappeared, during which eructations of wind occurred several times. Two h. later I had feeling as if stomach hung by a thread, which feeling, however, lasted only a short period, but the emptiness of the stomach only first disappeared towards noon. About 3 h. after dinner head suddenly felt

very dull, with slight pressure from forehead towards temples and stoppage in cars, which, however, again disappeared everv time he yawned. 3rd. — M., 5 dr. The emptiness in stomach returned an h. after taking medicine, but ceased 4 h. afterwards with emission of flatus, more down* wards than upwards. Head was frequently dull in course of forenoon, with giddiness. In afternoon again the troublesome feeling of stoppage in botn cars. 4th. — M., 5 dr. in forenoon I noticed, with exception of feeling of emptiness in stomach, no phenomena -, towards noon great desire for food, which increased almost to bulimy. Appetite very good ; after dinner, however, great weakness and sleepiness. Towards e. incarceration of flatus and frequent rumbling in the hypogastrium. In n. frequent frightful dreams. 5th. — 6 dr. Directly after walking I felt great looseness of bowels, which was followed in 4 h. by a pappf^ stool, with emission of much wind, without the feeling as if diarrhoea would come on ceasing. After the evacuation I took the 6 dr., whereupon soon constant and great borborygmus followed, and 2 h. after (hat a second copious almost watery evacuation. Throughout whole d. great weariness, and in afternoon great inclination to sleep. 6th. — As the rumbling and threatening of diarrhoea continued till this m. I took no medicine -, subsequently the feeling of emptiness was less remarkable, and the yawning seldomer. Appetite good. In afternoon again great sleepiness, and about 7 p.m. great duJness of head, with vertigo. There also showed itself after waking a large vesicle in red part of upper lip, which already began to dry towards e. 7th. — Early in m., ^ting, 6 dr. Half an h. after breakfast I felt great distension of bowels, which, however, abated after a loose motion and emission of much flatus of a strong, almost putrid odour. To-day I noticed the lower lip greatly swollen and rather burning, after which again a lar, vesicle showed itself, that formed next d. into a scab and scaled ofl all round. In afternoon great sleepiness and profound sleep with vivid dreams, as during n. At 7 p.m. strong pressive frontal pains, with threatening of vertigo and great weariness. 8th. — Early in m. 6 dr. An h. after its administration I had again that pressive sensation in stomach ; later frequent yawning and eructation of mere gas, which symptoms disappeared towards noon, when I had a very good appetite. In afternoon slight propensity to sleep ^ towards 5 — 7 p.m. frequent returns of giddiness. On lower lip a second vesicle, which contains much lymph. Although I took no medicine, still the same pressive sensation in stomach, with emptiness and frequent yawning, recurred about same h. as on previous d., and disappeared towards noon. In a^emoon head was less dull and giddy. Stools became again more regular, firmer, and only once a d. The scabs on both lips began to dry up ; at same time epidermis cracks, lip bleeds easily, and causes burning, 1 0th. — 6 dr. The abdomen feels tense, but loses this tension in about 3 h. ; in afternoon great weakness, with great dulness of head, nth and 12th. — No medicine. Inclination to constipation, inasmuch as the evacuations first occurred in afternoon, and are more solid than usual. In course of these 2 d. frequently during d. slight drawing in both legs, in 1. arm and thumb. Scabs on lips are falling off, the epidermis cracks and bleeds easily. 14th and 15th. — Each d. 10 dr. An h.

after each time of talcing medicine I noticed Ailnefls in stomach, and soon afterwards below that organ slight tension, which disappeared again 2 h. after; at same time I had constantly a very good appetite, which bordered almost on bulimy. From 5 to 6 p.m. head was dull and giddy. i6th, 17th, and 1 8th, — Without medicine. The forenoon passed without any remarkable phenomena, yet no afternoon came without the head being dull, with ringing in ears, beginning at 5 o'clock, but only lasting an h. 19th. — 15 dr. Even in an h. after talcing them 1 felt region of stomach greatly distended and whole abdomen tense, with rumbling therein, which, however, again disappeared in 4 h. About 4.30 p.m. I suddenly felt violent pressive pain in frontal region above both eyes ; whole of head felt dull ; heaviness in occiput, with pulsation and stiffness in nape of neck j chiming and ringing as of bells in both ears, with feeling as if J would fall to the ground in attempting to stand. These phenomena continued alternating for about 2 h., and a cup of coifee seemed to aggravate the pains. Although I took no medicine for 5 d., I felt still every afternoon at same hour the above phenomena, which, however, became daily weaker and less troublesome, until they ceased entirely on May 2Sth. 26th, — 15 dr. In forenoon I observed nothing particular, but in afternoon phenomena similar to those of March 19th appeared, and were repeated daily for 4— 5d.

b. From 15th to 17th April, each d. 5 dr. 5th dil. Excepting frequent yawning and incarceration of flatus with feeling of tension in the abdomen, I remarked in course of forenoon no phenomena. From 5 p.m. slight threatening of pressive headache, which, however, continued only a short time. 20th — lyd. — Daily 10 dr. Abdomen wa$ dunng these d. more distended. The pressure in stomach returned again frequently, during which for sake of relief 1 was obliged to yawn frequently. Stools certainly regular, yet looser. In afternoon great inclination to sleep ; fits of giddiness. Subsequently head was more dull. Pressure in r. forehead, sensitiveness of eyes, pulsation and stiffness in neck upwards towards occiput, which symptom first began to abate in about 2 h. Even the nights were more restless and disturbed by vivid dreams, so that on awaking I felt head still very dull and heavy.

c. The 13th, 14th, and 15th Nov., 5 dr. of 4th dil. In forenoon I was troubled with fulness and tension in abdomen, with the feeling as if an emission of flatus would follow constantly \ if an emission did take place, or an empty eructation was repeated a few times, then tension soon abated. Evacuations became daily scantier^ and it was only with trouble that I parted with very dry stools. The 17th, l8th| and 19th, 15 dr. The diflicult scanty stool passed into actual constipation, during which a hard stool followed only every 2nd d. — an extraordinary phenomenon in me for years ; at same time I felt very well and had a particularly good appetite. I was attacked on 20th with a catarrhal fever that lasted 4 d. ; on which account I took no medicine. During this time the constipation ceased again, and the stools appeared daily as usual. The 2^th, 28th, and 29th, 10 dr. 3rd dil., daily. A couple of h. after each act ministration of the above I noticed repeatedly congestion

i^OL. in. 25

and heaviness of head, which became more violent every d., and in afternoons degenerated into severe, semi-lateral, shooting headache in r. forehead, with transient painful shooting in eyeball, recurring in three attacks of 2 — 3 h. and first disappearing completely towards 9 p.m. Even the nights were more restless than usual, and on awaking 1 felt still heaviness and dulness of head.

d. The 2nd, 3rd, and 4th Dec, 5 dr. of 2nd dil, daily. With exception of slight dulness in head, with vertigo and emptiness of stomach, I perceived during forenoon nothing ; in afternoon, however, head was duller, with beating in occiput. 5th, 6th, and 7th. — lodr. daily. As the ordinary stool did not appear, abdomen was distended whole forenoon, and tension first commenced to abate in afternoon after several emissions of offensive gas. Frequent tickling in rectum. Frequent urination; urine seemed hotter; also I experienced slight itching in orifice of urethra. Frequent erections during n.,and dreams that he had gonorrhoea. 8th and 9th. — Without medicine. The stool certainly appeared again daily, but with greater effort. The itching con* tinued in rectum, and was relieved by scratching ; I also perceived itching in legs, particularly inner side of calves. lOth, iTth, and I2th. — 15 dr. of I St dil. m. and e. daily In course of d. I perceived no troublesome phenomenon ; instead, however, the sleep was very uneasy, and disturbed by frequent waking and constant vivid dreams. In spite of taking no more medicine for 7 d., the irregularity of stools, which were always difficult, the dulness of head, the periodical attacks of giddiness, especially in forenoon, the beating in occiput and the itching and burning in rectum continued. 20th. — Early in m. 20 dr. of ist dil. Two h. after taking dose head became very dull and giddy, with sparkling before eyes. At same time frequent yawning, which always relieved head. Towards afternoon frequent eructations of empty gas without any odour. Nevertheless appetite was excellent. Alter the meal I was seized with great sleepiness, which I could scarcely keep off. There suddenly occurred at 5 p.m. an exceedingly violent pressive headache proceeding from r. temporal region towards half of forehead and r. eye. At same time ball of eye was very sensitive. The slightest touch aggravated the pains, and made them almost unbearable ; light also was extremely troublesome. These attacks continued alternately for about 4 h. ; after drinking much water became somewhat better, but first ceased completely after a full supper which I thoroughly relished, and which was followed by a good n. Since 20th I took no medicine, and yet for 3 d. the above phenomena returned always at 5 p.m., in less degree every d. [Ibid*)

1. Dr. WuRMB proved first the dilutions, then the raw material, and then returned to the dilutions. He took on each occasion 10 dr. of the dils.

a. The 30th dil., taken Feb. 24th, 1843, in e., on 26th, 27th, and 28th, and March 2nd, 3rd, and 4th, m. and e., showed itself on n. of 24th by vivid dreams, on 25th in forenoon and 26th by dulness of head, accompanied on 3rd during whole forenoon by rumbling in belly and four pappy diarrhoeic stools, in e. by chilliness even in neighbourhood of warm stove, and accelerated pulse <ioo). Usual evacuation

\d on 4Ch. From March 6th to toth a dose of 27th dil. dailv m. and e. produced no symptoms, excepting that on 7th the stool did not appear as usual in m. but Hrst towards e., and insufficient, loose, with much straining ; but on 8th totally failed, — a phenomenon which the prover believes he may ascribe with so much the greater certainty to the medicine taken as he has every m. (punctually) immediately after rising a proper evacuation of the bowels. The 2+th dil. was taken on iich and 12th, m. and e., without any effect whatever. But much more powerful effect had the zist dil., which he took on 13th, 14th, and 15th, and after omitting on 16th continued for 3 d. further m. and c. On 13th he had in m. an insufficient evacuation, but felt quite well rest of d. About 7 p.m., however, he had feeling of chilliness in arms, thirst, accelerated pulse, repugnance to food. The feeling of chilliness spread itself gradually over whole body, and disappeared first 4 h. after, followed by heat with shooting in integument of whole body. The heat continued 1 h. During tnat time he sneezed frequently. Sweat now appeared, which had a sour smell and lasted till 2 a.m., at which hour the attack of fever terminated instantaneously. He was fetched at 2 a.m. to a patient, but felt himself, in spite of previous fever, quite well. About 3 he returned to bed, and soon fell asleep. The sleep, however, was not composed, but disturbed by vivid fearful dreams, by frequent waking, and constant tossing about in bed. The following a. head was dull, he felt weary, but only in sitting, had now chilliness, now heat or sweat. The pulse was accelerated the whole d. (a few beats in m.). After dinner frequent emission of flatus. At 4 p.m. an insufficient evacuation appeared after much straining. In e. he frequently sneezed j he had sensation as if cold in head would come on. He was frequently awakened out of his sleep at n. by vivid dreams. On isth in m. he had an insufficient stool with much flatulence. The ]6th and )7[h passed without any symptoms. On i8th felt a few times painful pulsation in I. temple towards occiput ; Indisposition to mental exertion (want of ideas) ; forgetfulness i no evacuation that d. In e. in walking feeling of heaviness in feet ; sleep disturbed by vivid unpleasant dreams and frequent waking ; each time he awoke dull pain in head, and sweat. On 19th in m. in spite of violent urging to stool only an insufficient evacuation, accompanied with much emission of gas (which was repeated after dinner). The iSth dil. was only tried for 3 d. (20th, 21st, and 22nd). On ist d. no symptom showed itself. On 2nd, delay of stool till e., when an insufficient evacuation with loss of blood from the hemorrhoidal vc^isels followed. Thereupon pain as if bruised in sacrum. On the 3rd m. dulness of head, as if from impendmg coryza i an insufficient evacuation with shooting in anus. The pain as if bruised in sacrum showed itself alternately weaker or stronger, and lasted whole d,, particularly when sitting. The i5ih dil., taken from 23rd to 26th like the previous dilutions, was followed on 23rd by sensation in I. popliteal space as if tendons were tense j during whole d. troublesome gnawing in I. os calcis ; in afternoon in sitting, chilliness, which disappeared when he went out at 5, but returned in e., though weaker, in sitting j before falling asleep pressure in sacrum. At n, vivid dreams and frequent awaking. At midnight

profuse sweat, especially oa chest- On 2+th short cough, dry returning dunng d. frequently, dov at shorter, now at longer intervals ; pressure in middle of sternum and in lack below 1. shoulder j dulncss of head, troublesome pulsation at base of skull ; constipation ; the gnawing in the heel occurs again for a moment in e. i at n. vexatious dreams and frequent waking. On zsth no symptoms showed themselves. On 26th constipation. After the prover had omitted several d. on account of a violent cold he commenced in the above manner on March 31st till April 2nd with the 12th dil. The first n. he had again vivid dreams and awoke often. On 2nd he had in m. an insufficient evacuation, distended hamorrhoidaJ veins, painful to contact, pappy taste in mouth. In second half of n. vivid dreams and frequent awaking J on 3rd d. the same hemorrhoidal troubles as on previous d., slimy, bitter taste in mouth, with proper taste of food ; in e. frequent hawking up of bitter mucus. The gch dil, was proved from 3rd— 6th, and after an interruption of a week from April 14th to i6th. 3rd.— ^ In m. scanty opening of bowels j slimy, bitter taste in mouth ; whitecoated tongue (particularly at base) i frequent hawking up of phlegm j towards c. cutting in belJy (flatulent colic), call to stool and a pappy evacuation, whereupon abdominal symptoms disappeared j in e. a scraped, raked condition of throat. 4th. — Constipation ; tongue, taste and hawking up of mucus as yesterday ; sensation of heat in anus and I. testicle ; pressure on sternum, m afternoon ; in 1. popliteal space and in 3rd, 4th, and 5th toes of r. foot, feeling as if tendons were too short i at n. anxious dreams, so that he cried aloud ; frequent awaking. 5th.— Constipation ; at n. frequent erections ; at the same time burning in fbftsa navicularis of urethra. 6th. — Burning in urethra in early m. in urinating i scanty stool; throughout d. frequent threatening of headache j night's rest disturbed by painful erections j towards m. a seminal emission. 14th and 15th. — No symptoms. 16th. — Constipation, distension of belly, emission of much Batus. The 6th dil., taken from April 17th to 21st, like all the previous ones in doses of 10 dr. m. and e,, effected on ist d. no remarkable change j on 2nd unusually frequent micturition y on 3rd d. constipation j on 4th in m. a hard inmficient stool after much straining and violent pains, as if rectum would burst, followed by bleeding from hemorrhoidal vessels, and the vbolc forenoon pressive pain in rectum and frequent urination; in Afternoon tension in 1. foot, particularly on inner side of thigh, and some very sensitive shoots in 1. popliteal space ; on 5th, almost whole d. through, pressive beating pains in head, particularly in 1. region of Ibfchead, failure of usual stool in m., after dinner contractive pains in bcAXt hereon emission of much flatus and a hard scanty stool with burning in anus^ which continued almost whole e.

J^ The 3rd, 2nd,* and ist irits., prepared in the proportions of 1

of medicine to 99 of sugar of milk, and taken from 3 to 4 d. m. and e.

lin <k9et of 10 gr., produced partly none, partly only very few symptoms ;

f^ 3rd trit. on 1st d. induced delay of stool tiJl e., when a hard, scanty

[«\ai'uaiion appeared after great discharge of flatus j on 2nd d. constipa-

and trequent micturition. The ist trit,, on 2nd d., caused slimy

• Bftwccn the proviD^t ul the jrU and &Dd irit. conies vi inten-al of 6 moathi.

I p

taste in mouth, scraping in throat, and in e. an attack of tickling cough, which lasted almost i h., and terminated with coughing up of tenacious mucus. Not much more productive was a seven days* trial with the first trituration prepared in the proportion of 10 : 90. On 1st and 2nd d. (after 55 gr. at 9 a.m.) he had towards c. a profuse, pappVj and \ h. later a Buid evacuation, although he had in m. his usual normal stool. On 2nd d. he had, prior to the appearance of the fluid stool, cutting in hypogasirium. On 3rd and 4th d. (after 55 gr. m. and e.) stool did not make its appearance ; the appetite was considerably increased. On latter d. in e. attack of tickling cough came on, which ended after 10 m. with coughing up of saltish phlegm. On 5th d. (after a similar dose) the (scanty) evacuation was retarded until afternon, and occurred only after much straining. In e. several attacks o( tickling cough appeared. The same attacks were repeated in e. of the 6th d. (after iio gr. in m.). Tonsils, soft palate, and uvula greatly injected. The 7th d. (after another 110 gr.) passed without any symptoms. A further trial of 3 d. with the 1st irit. prepared in proportion of i : 5 was likewise without results.

c. Wb^ now proceeded to the proving of the raw material. He took of it on Nov. 10th, iith, and 12th every m. 5); from 13th — l8th 5ij ; 20th 5iij j 22nd ^ oz., which he repeated on 25th, 26th, 27th, and 29th. The 30th he increased the dose to 3VJ, and concluded on Dec, ist with r oz. The salt for this purpose was on each occasion dissolved in water (4 tablespoonfuls to 1 drachm). These large doses enriched the sphere of action of salt by only a few symptoms. The results are comprised in the following: loth. — Increased desire for food ; sensation in 1. popliteal space as if tendons were too short, returning frequently in course of forenoon, most frequent in rising from a scat ; in e. cutting in hypogascrium ; frequent attacks of dry tickling cough ; stoppage of nose ; sneezing i frequent urination (also during n.;. The latter phenomenon continued also the following d., iith. After 2 a.m. he was frequently awakened out of sleep by vivid dreams. I2th. — Constipation j frequent micturition. The n. from 13th to 14th was sleeple>s from 2 o'clock. 14th. — The stool failed; following d. was insufficient. The 1 6th was completely void of symptoms. The 17th he had again constipation. In n. prior to i8th he awoke about 3.30 and lay wide awake for an h. When he fell asleep after that he was tormented with anxious dreams. From lOth to 18th the sexual instinct was unusually active. The .-^iij of the 20th created .soon after their administration nausea^ accumulation of water in mouth, vomiting of a watery fluid with subsequent great thirst, which first ceased after drinking much water, in course of d. secretion of urine was diminished, stool constipated. Sleep was disturbed from 3 a.m. by vivid dreams and frequent awaking. He was also obliged during n. to rise once to micturate. 2i5t, — Frequent urination. The following n. the phenomena of the previous d. j besides these, great sweat. 22nd. — After 4 oz. no stool for 2 d,, then the 3rd d. an insufficient stool, e. 25th. — Same dose caused constipation, frequent micturition, sensation of shortened tendon in hough, night's rest broken by vivid dreams and frequent waking. Similar

nocturnal disturbance occurred after same dose the 2 following n.— .a7ih. M., a scanty stool; noon, a copious pappy stool ; n., liquid stool; ^abdomen much distended. Frequent hawking of salt-tasting phlegm, violent, almost unquenchable thirst, frequent and copious micturition. On ^qih after i oz., and on 30th after 6 drm., immediately violent thirsty slimy, bitter taste, hawking of salt phlegm. AJl symptoms went off after breakfest. On 29th repeated feeling of shortened kneetendon, a.m. On 30th cutting pain in hypogastrium, with violent urging to stool, followed by copious pappy stool, and after i h. watery diarrhoea. Dec. 1st.— i oz. in J pint of water. This caused imme- ■diatcly flow of saliva into mouth, inclination to vomit, cough, frequent blowing of nose, scarcely quenchable thirstj disgusting pappy taste. After 1 h. cutting in hypogastrium, frequent urging to stool, and very copious evacuation, partly pappy, partly watery. After dinner quite well except tensive sensation in legs, especially houghs. Next 4 d. no or very scanty stool, and (3rd) increased secretion of urine ; heartburn and frequent hawking of salt mucus, e. ; on going to sleep violent itching in both calves. Frequent waking n. — 4th. After dinner very exhausted, as after great exertion, but only when sitting. Ftom Dec. loth to 18th took 10 dr. of 30th and 27th dil. n. and m,, and had very similar symptoms, and in addition cramp-like contraction in calf-muscles for several h. [Ibid,)

1. Prof. V. Zlatarovich proved drug on 11 of his students.

a. As — , <cc. 22, took from Nov. 7th, 1843, ^^ J*"* '8th, 1844, every m. 10 gr. jst dec. trit. During all the proving his digestion w.is deranged, he had little appetite, very furred tongue, insipid pappy taste, increased saliva, much flatus smelling of sulphuretted hydrogen, occasional purging. Urine diminished, yellow, causing burning in urethra. Sleep always restless (though very sleepy e.) ; dreamt much, which was unusual. After waking often headache \ sometimes transient tearing pain in calves. In the middle of the proving troubled with great itching of skin for 14 d. ; after scratching small vesicles appeared.

b, Kr — , St. 21, made a similar proving. During past month experienced nothing but increase of saliva, slight burning in stomach and bowels soon after taking the dose. Afterwards had itching in various parts, especially about I, knee-joint. After scratching nettlctash-likc spots soon going ofl'. Stools irregular, sometimes liquid, sometimes none. N. frequently restless, full of dreams, sometimes quite sleepless.

f, Kk — made a similar proving, but had to stop taking the mcd, from 8th to 26th Dec. on account of bilious fever. From Nov. 7th to Dec. 8th his report is : — In the first days no effect except a moderate headache, to which he was not subject. On 6th d. a diarrhceic stool, and this happened daily throughout the proving. He had previously been very irregular in his stools. He had also been subject to painful fits of piles twice a month, but had none during the proving. But his sleep, which had previously generally been sound, was often disturbed and broken, and he was 'often very drowsy by d. In the second period of the proving, from Dec. 26th to Jan. 14th, the symptoms observed during the flrst period recurred (excepting the head-

39 »

ache), and there was an extremely disagreeable itching all over the skin of the body, which was particularly bad at n. and did not allow him to sleep well.

d. Mt — ,a;t. 2i,madeasimilar proving. During the first week he was much troubled with flatulence, but the digestion was unimpaired. Afterwards he had congestion of blood to head, restless, short, broken sleep with many dreams, often complete sleeplessness, increased sexual excitement, occasional emissions. In the m, he was generally cross. Towards the end of the proving his digestion was deranged, he had furred tongue, bitter flat taste, especially m., sometimes vertigo and stitchings in head. Urine and perspiration rarely increased.

e. Pd — , aec. 23, made a similar proving. The past 5 d. he had, immediately after the dose, shooting in temples, aher dinner great drowsiness. Later on increased saliva, flatulence and swelling in bowels, itching all over body, especially on head.

f. Pj — , a£t. 25, made a similar proving. He previously suffered from constipation, but since commencing the med. the bowels became regular, he felt stronger, was not so sleepy in e., his disposition became more cheerful. Immediately after commencing proving, there broke out on his back numerous pustules which gradually became small lumps and disappeared after he ceased to take the medicine.

^. Ro — J xt. 22, made a similar proving. Before this his bowels were opened only every 3 or 4 d. and the motions were hard. They now became normal. The symptoms he observed were, low spirits, vivid dreams, which disturbed sleep, especially after midnight, hawking up of much phlegm, after waking, m., subsultus tendinum in thighs, often for several m., itching in sacrum, spreading to belly and hepatic region and thighs, weariness of lower extremities, mostly m.

A, Sk. — , art. 23, made a similar proving, The first weeks he only had great drowiiness, exciting dreams, transient stitches about pylorus. Later great sliminess of mouthy flatulence, rumbling in stomach, uncommon urging to urinate, nocturnal emissions, very hard stool, constipation. The constipation only occurred when he took the dose before breakfast, not if he took it after breakfast.

I. So — made a similar proving. He observed diminished perspiration, increased saliva and urine, restless sleep, vivid dreams, seminal lemissions. Before the proving his digestion was usually bad, he had pressure in stomach after a meal, usually 2 stools ad. During proving he had good appetite, his digestion was good, and he had one normal stool per diem.

j, Ss — , act. 21, made a similar proving. He complained at first of flatulence, but his digestion was better than before ; increase of mucous secretion in mouth, especially m., occasionally spasmodic contractions in muscles of upper arm. On Dec. 8th he had an attack of hxmoptysis which he ascribed to unusual exertion. But as this attack was renewed more severely and without apparent cause, on the 17th he stopped his proving. On the i ith it was without any effect, (Ibid,)

1. PoGGJALE examined the blood of a man, both at the time that the usual diet was taken, and whilst 154 gr. of salt were consumed daily. The following are the results :

During usual meal. While talt wa» taken. Water .... 7799 • • • 767'6 Blood-corpuscles 1 301 ... 143*0

Albumen .... 774 ... 740

Fibrin .... 2-i ... 2*3

Fatty matters . I'l ... 1*3

Extractive and salts . . 9*3 ... 11 '8

{Cemptes-renduSy t, xxv. 1847).

1. Confirming conclusions already published by Voit {Brit, and For. Rev.^ ii, 1862), Rabuteau has shown that N. m. increases vital combustion ; for while taking an extra daily dose of 10 grm., his excretion of urea was 20 per cent, more and his temp, half a degree higher, than when under a dietary from which salt was excluded. Similarly Knapp found that with taking I grm. of salt, the amount of urea excreted was increased 4 centigr., the other soluble constituents of the

urine being diminished An excess of dose causes not only

thirst and disordered digestion but also impaired blood conditions. . . . Very large and concentrated doses cause vomiting, watery purging, and even gastritis. (Phillips, op, at.)

IL Poisonings. — i. A girl, set. 184, of scrofulous constitution, had suffered till her 14th year from various scrofulous affections, such as ophthalmia, tinea capitis and running ears. Before the menses came at 17 she had a kind of chlorosis, pale face, nausea, anorexia, weakness and emaciation. The menses were for a long time of a morbid character^ scanty, irregular, pale and watery. During that time,/./, for i^ J^sat, she had an insuperable desire to eat salt and sugar alternately and she often had voracious hunger for bread and ht thmgs. From this time there appeared on her hand innumerable warts (she had previously only 2 or 3) so that not a pin*s head in size of the hands was free from them. She also had for a year slight attacks of spasms in the stomach which gradually increased and were accompanied by spasms in abdomen. She also grew thinner and paler. She only sought medical advice on Dec. 7th, 1832. She presented then the following symptoms, which correspond tolerably to symptoms of Natr. mur. recorded in Hahnemann's Chronic Diseases, Very pale suffering appearance with sunken dull eyes surrounded by blue rings. On account of weakness she slips from one chair to another, but feels best when lying, which she does for several hours during d. Her countenance betrays the highest degree of sadness, crossness, irritation of disposition with tendency to anger and quarrelsomeness j she readily bursts out crying. Disinclination for work. She is vexed at having to answer questions. The circumference of her body has strikingly diminished. She has become thin. Heat of mouth ; heartburn, sour taste, loss of appetite, constant loathing, nausea, with flow of saliva into mouth. Feels as if a plug were sticking in her diroat, with contraction. Sour and slimy vomiting, generally 2 h. after eating, followed by headache ; after a meal immediately feeling of fulness and pressure in stomach with contraction ; shooting and cutting in bowels i burning in abdomen from below upwards. Chill all over body after vomiting -, great chilliness of back ; tearing in back from above downwards, worst in afternoon. Menses irregular and scanty. Hands full

of warts. For 2 months she was treated with nux vomica, ipecacuanha, veratum album, bryonia, Arsenicum and rhus tox., but in vain. On the 31st Jan. the antidote of Natr. m., sp, nitr. dulc, was commenced, and in 6 d. almost all the morbid symptoms were gone. She regained her appetite and could retain food. All the warts dried off in a short time. She recovered her former good spirits and cheerfulness and became strong and blooming. (Engelhardt, Oest. Zeits.f. Hom,^ iv, 17.)

1. A big, thin, darlc-complexioned man, act. 32, complained of the following symptoms : — Loss of memory, so that he can with difficulty find the right word, forgetfulness, dazedness in forehead, and loss of ideas \ want of sympathy, misanthropy, prefers to be alone, low spirits, sadness, fear of some serious illness, though he is indiif'erent to life. Pressure and heaviness in occiput, worst after eating -, weariness ; heat in head when eating \ pressure and heaviness of eyelids, so that he can with difficulty keep them open. Itching ulcers in nose ; aching in right lower maxilla ; yellow spots in face. Burning in tip of white furred tongue ; white watery saliva accumulates in mouth when speaking ; undefined toothache in afternoon. Itching eruption on scrob. cordis. Pressure in stomach after food \ many flatulent sufferings j stool pappy, followed by exhaustion. Constant irritation in genitals. Intermittent heart-beats with anxiety, in afternoon. Bruised feeling in sacrum, especially m.^ when standing or walking j lame feeling in sacrum ; boring pressure in sacrum when sitting ; prickling and formication on skin of sacrum. Tearing in bones, at one time of arms, at another of legs; slight tearing-drawing in hands and feet ; prickling in tips of r. fingers and in r. big toe ; falling asleep of hands and feet. Great exhaustion, especially m. Itching all over body in different places ; dislike to cold air, chilliness in open air. The doctor thought these symptoms had such a strong resemblance to those of Natr. m. that he prescribed that as a remedy. But as the patient became worse, he made inquiries and found that he was a great salt eater, so he gave sp. nitr. dulc. 2 dr. in a tablespoonful of water to be taken during the d. by teaspoonfulsj and in 4. d. the chief symptoms were gone. (Neumann, Ihid.y 19.)

2. [in the 8th vol. of this journal (p. 435) is described a case of " purpura hamorrhagica," which the present writer considers one of *< scorbutus pctechialis.'' It was curious in that the patient bore venesection to a surprising extent, — 86 oz. of blood having been taken (independent of the haemorrhages) in 18 d. ; and that the blood had a thick and firm " bufFy coat." The writer goes on : — ] "This copious appearance of coagulable lymph would, at one period of medical opinion, have been thought incompatible with so high a state of scurvy. But I have met with several cases of scorbutus petechialis similarly characterised, and unexposed to any of those causes which are generally considered as alone productive of this malady. In every one of these cases 1 discovered that the patients had indulged an inordinate inclination to common salt ; and there is one expression in the case so well related by Dr. Jeffreys which inclines me to believe that the disease in his patient had a similar origin — * He craved much for his usual diet of salt beef.' .... I have no doubt that a free use

of common salt during a certain length of time will be capable of scorbuticising the system with the same certainty that mercury will produce salivation.'* (SHERWEN, Ed, Med, and Surg, Joum,^ x, 44.)

1. Mr. T — , suffering from dyspeptic symptoms, prepared, Oct. loth, a mixture of two tablespoonfuls of salt to Oss of brandy, of which he took about two teaspoonfuls m. and e., shaking vial before each dose. On m. of 14th, shortly after taking his dose, he noticed slight itching of skin about neck and under chin. He found that scratching did not relieve him, but itching rather grew worse. Upon examining parts affected, he perceived a faint blush of red and very trifling svi^iing, but no distinct eruption. He now began to experience considnable burning of skin accompanying the itching, and during d. irritation extended down chest and arms, then down body to lower extremideSi even to feet. He began to suspect the salt and brandy, but took his usual e. dose. After tea itching and burning began again with tenfold violence, and was almost intolerable. It passed from above downwards as before to soles of feet, where he experienced the greatest suffering. To use his own words, — " I could not have suffered more if I had been walking upon red-hot coals." His feet felt swollen, but no swelling was perceptible to eye. This intense suffering lasted nearly } h., when the irritation went off, leaving him comparatively comfortable. He had slight itching of body during n. Next d. he omitted m. dose, but after break^st and again after tea he experienced a similar attack to yesterday's, that in the e. being even worse than before. On 3rd and 4th d. he suffered in like manner, but less in degree, being always worse after tea. (Bartlett, N, A, J. o/H.y ii, 132.)

2. A child of 6, healthy save for a lameness of r. leg, was for this ordered complete rest. In consequence constipation occurred, and to overcome it she was ordered an enema in which a considerable quantity of common salt had been dissolved. During following n. she became very thirsty, and drank large quantities of water, passing also much urine. These symptoms continued, rather increasing than otherwise, from May, 1868, till November, when Professor Abelin saw patient.

The amount of fluid taken in 24 h. at beginning of June was over a gallon^ and the quantity of urine voided in same space of time was somewhat under a gallon. Patient by that time had commenced to lose flesh and strength. Her appetite diminished, and sleep was interrupted by need of allaying thirst and voiding urine. Bowels have been regular ; no perspiration, skin being generally cold. Temper has become irritable and peevish. Nov. I2th. — Patient is of ordinary size and development for age ; face tolerably plump, but body thin. Skin pale, dry, elastic to feel ; temp, normal. Thorax laterally somewhat compressed ; resp. even, uniform, and calm. Heart normal ; pulse full, soft, 92. Tongue slightly coated whitish yellow ; appetite indifferent i bowels regular ; abdomen somewhat enlarged, but soft and resonant. Urine clear, of peculiar greenish colour and feebly acid reaction ; becomes frothy when shaken, its sp. gr. in m. is X005 ; p.m. 1 004. M. urine shows by nitric acid test evidence of albumen ; in afternoon no trace of it. In the specimens hitherto microscopically examined no tubular casts found. At end of i ^ years A— heard that

I I

patient's state had not changed, in spite of treatment. (Brit, yourn.oj Hom,y xxxi, 415.)

1. E. A — 5 at. 28, having enjoyed almost uninterrupted health until a year ago, since then had been in a very infirm state, and compelled to relinquish the teaching by which she lived. Dr. Hare saw her March 2Ist, 1B54. Her mind seemed hopeless and confused. Her chief complaint was of great chilliness, accompanied by languor; headache and great dyspncea every m. about 3, followed by great heat with thirst, which terminated in profuse perspiration. It was elicited that just before her illness she began to eat salt as a vermifuge, and in course of time acquired a taste for it and habitually ate it in great quantities. Xhc quantity consumed daily seems to have been about ^j or .^'^s* ^^ further inquiry, the following symptoms were ascertained : — Constant craving for food, but is unable to eat more than a (ew mouthfuls, immediately after which she feels distended almost to suffocation, and has violent palpitation \ thirst constant \ great pain at przcordium after eating or drinking; heartburn and waterbrash daily, occasionally empty vomitings ; gums arc sore and swollen, and bleed easily ; breath foul \ submaxillary glands swollen, stiff^, and painful ; tongue red and shining; bloody saliva runs from mouth at n. ; voice completely changed, is husky and monotonous, resembling that of a woman addicted to ardent spirits ; uvula much swollen and elongated, clinging to r. tonsil ; vessels of throat much congested. Periods very uncertain, at first every 2 weeks, now 6 or 7 weeks frequently intervene. She is generally chilly, but each n. suffers excessively from rigors, followed by heat and profuse perspiration ; as the rigors come on, and during their continuance, her languor is excessive, and the headache and dyspncea almost indescribable. Urine is scanty, but there is constant desire to micturate; it is painfully acrid, contains three times its proportion of chlorine, and deposits large quantities of uric acid. She is naturally constipated, but for last 3 mos. has suffered much from constant diarrhuea. She complains of rheumatic pains in arms and legs ; feet and ankles are particularly painful and stiff. Her hair has fallen off, and she is occasionally troubled with an itching eruption on her scalp. Her perspiration was so saline as to produce excoriation on parts of body where skin was thinnest. His mind was much weakened ; her once keen sense of honour and of right and wrong seemed blunted ; she was in turns vehement and passionate, moody and silent. Omission of the salts effected little change, nor did arsenicum, but sp. nitr. dulc. speedily initiated improvement, which under other remedies went on to complete recovery. [Alonthl. Horn. Rev,^ iii, 211.)

2. I always suffer when 1 have eaten anything salted, as bloaters, &c. When salt is used as a condiment I suffer from thirst and a sensation of heat over the whole body, a kind of fever. After having uken much salt I suffer from eructations, even vomitings; flatulency; bad taste in mouth, &c. (LiEDUECK, Brit. Journ. of Ham.^xxx^ 405-)

3. A patient tells me that whenever &he eats salt her breath becomes short and chest tight and as if a dry stick of wood were down throat, with cough. (Berridge, M T. Journ. of Hom,^ i, 31a.)