Anilinum

(Amidobenzene.) C6H5

NH2

• Lailler (Gaz. Heb., 1873) (M. H. Rev., Jl., 1873).
• Local application of 10 per cent. solution of the hypochlorate to psoriasis caused, in a hour and a half, vomiting; repeated fifteen or twenty times during the night; incontinence of urine, with a little tenesmus; night restless; the next morning the face and nearly the whole of body cyanotic ; pulse 116, small, regular; slight râles in chest; severe pains in heels and calves. A second application (afterward) of a 5 per cent. solution caused, in two hours, headache, irresistible drowsiness, coldness, and dyspnœa; cyanosis very marked; voice very feeble.
• In another case, a solution of 2 per cent. caused, in four hours, loss of consciousness (lasted fifteen minutes), deep cyanosis (lasted five hours); respiration regular; cyanosis, followed by great paleness and cold sweats; following night sleepless; urine high-colored.
• A boy, cleaning an aniline vat, inhaled the fumes, and was suddenly seized with giddiness, and became insensible; the face and body became cold, pulse slow and almost imperceptible, action of the heart feeble, respiration heavy and labored; after rallying a little he complained of pain in the head and giddiness; his face had a purple hue, as also his lips, mouth, and nails; this blue color (like a patient in last stage of cholera) continued the next day.
• Case related by Mr. Knagg, of Huddersfield, Hom. Obs. (Eng.) , 1, 64. James K., aged 39, of average health, was directed, about noon, to empty four carboys of the nitrate of benzole into a still. By mistake, the last one contained aniline. On lifting it, he struck it against the edge of the still, and it was broken, the whole contents pouring over him; none entered his mouth, but the fumes were freely inhaled. About an hour afterward "he broke out into a sweat, and felt quite giddy, and weak in the head and stomach." At 11 P.M., he presented the following appearance: Face and whole body of livid, leaden hue; lips, gums, tongue, and eyes of a corpse-like yellow; gasping for breath, as though it was his last. There was no convulsions, and he was perfectly sensible and able to give a correct account of his feelings; pulse extremely small and irregular. The only pain of which he complained was in the head and chest. He recovered under the free use of brandy, ammonia, chloric ether, and cold affusions to the head, and mustard sinapisms on legs and thighs.

SUPPLEMENT: ANILINUM. Authorities. 3 , A. L. Carroll, M.D., Phila. Med. Times, April, 1873, p. 419, a woman, aged thirty years, suffering with rheumatic pains in the knees, bandaged them with red flannel; 4 , Same, a man wore a glove, the wristband of which was ornamented with a broad stripe of Aniline purple; 5 , M. Laboulbène, Gaz. Hebdom., 1876 (Med. Rec., vol xi, p. 382), effects on workers; 6 , M. Bergeron, ibid., effects of fumes on workers; 7 , Dr. Murray, Phila. Med. and Surg. Rep., 1877, p. 69, a girl, aged three years and a half, wore a pair of new scarlet stockings for a day; 8 , Henry P. Wensel, ibid., p. 188, Mrs. W. aged sixty-four years, took a teacupful of acetous solution of Aniline.

MIND

• Hebetude, 6.

HEAD

• Vertigo, 6.
• After three months he began to suffer from vertigo, 5.

EYE

• Eyes irritated, 5.

MOUTH

• After three months, bitter taste in mouth, 5.

SEXUAL ORGANS. [10.]

• After two months he began to complain of pains in the penis and scrotum, and these parts become swollen, and have remained so since. One month after these symptoms he began to suffer from loss of sexual power, 5.

GENERALITIES

• She had intense burning pain at the stomach, and in the head, after swallowing et, and she "could not get her breath." She took salt and water, but did not vomit until eight hours afterwards, when violent emesis and purgation set in, and continued until I saw her, when she vomited stringy mucus, mixed with blood; she was almost exhausted. Her extremities were icy cold, and the head cold and clammy; intense pain on pressure over the stomach which was hard and enlarged; tongue pallid in centre, and very smooth and red at the tips and edges; eyes injected, lower lids puffed; complained of burning pain in the eyes, and said "Oh my head will burst;" hard pulse, 84; temperature 98 1/4°; respiration labored, 44, 8.
• Sometimes epileptiform attacks, tetanic spasms, etc., 6.
• Weakness, 6.

SKIN

• Marked and permanent amaranthine discoloration of the hands, feet, and hair; this discoloration made its appearance since he began to work near the vats, from which acrid Aniline fumes escaped, 5.
• In the end, the workmen fall into a condition of profound anæmia, with discoloration of the skin, lilac tint of the lips, anorexia, gastric disturbances, etc.; but this state of affairs is promptly corrected by the respiration of pure air, or by inhalations of oxygen, and the use of evacuants, 6.
• A vesicular eruption forming a complete bracelet about the wrist, 4.
• Eczematous eruption affecting both knees. There was considerable tumefaction, much redness, and an intolerable itching of the skin; the condition being that of eczema rubrum, 2.
• The next day, the left leg was much swollen, covered with small blisters and presenting a mottled appearance, much like castile soap. A day or two afterward the right one became similarly affected, 7.

SLEEP

• Somnolence, 6.