Grindelia squarrosa

Volume I — Appendix

Description. — This plant belongs to the natural order of Compositce, and is a small herbaceous plant, indigenous to California.

The whole plant is permeated with a peculiar resin, which is most abundant in the flower-heads. This and O. robusta are very similar in appearance, and belonging to the same genus, their actions on the human organism are verymuch alike.

Preparation. — Tincture of the herb.

Head.

Terrible fulness in the head, similar to the effect produced by a large dose of Quinine. Pain in the left eye, and right kneejoint, precisely like acute rheumatism. The pain in the knee did not last long. The pain in the left eye became very intense, then the right eye was affected ; simultaneously with the affection of the right eye was an unbearable pain in the region of the liver and spleen, so severe that it was impossible to lie still. Pains like acute rheumatism.

The pain of the eyes was in the eyeballs and ran back to the brain ; pain increased by motion of the eyes. Characteristic of the pain wherever occurring was that of rheumatism ; pain with soreness.

The conjunctiva was remarkably injected. Eyes presented the appearance noticed in congestion of the brain.

Nervous System. Full doses act first on the optic nerve, and in a little time influence the par vagum and interrupt respiration. The disturbed respiration prevents sleep. The moment the prover fell asleep respiration ceased, and it would not resume until awakened by the suffocation that resulted from the suspension of respiration.