(NO2 )O3

Preparation , Dilutions with alcohol.

Authorities. ( Nos.

1 to 121, from Hering's revised Monograph in N. E. Med. Gaz., 1874 and 1875 ).

1 , B., from Dudgeon's provings, B. J. of Hom., 11, p. 284, took tincture; 2 , Battman took 1st centesimal; 3 , Belding took 2 drops of 2d centes. dil., Hahn. M., 4, 120; 4 , Benson, 1st dil. (probably), ibid.; 5 , Berridge, effects of 20 drops of 1st centes. dil.; 6 , Brangwin (Dudgeon's provings) took 1 drop of 1/10th; 7 , Brink took 1/250th; 8 , Bute, from Hering; 9 , S. B. (Lippe's provings) took the 1/50th; 10 , Miss C. (Dudgeon's provings) took 3 globules of 1/10th every day for three days; 11 , Castle took 1/100th, repeated in twenty minutes; 12 , D. J. Chaffee, Hahn. M., 4, 120; 13 , W. G. Chaffee, ibid.; 14 , P. Champion (from Hering); 15 , Cheveril, Chemistry (Hering); 16 , Colby, Am. Inst. Proc., 17, took 1/100th; 17 , Cutmore (Dudgeon's provings) took 1 drop of 1/10th; 18 , G. F. Davis took 1/100th, and after fifteen minutes the 1/50th; 19 , Morris Davis, touched crude to the tongue, and after some days took a drop of 1/10th; 20 , Dr. Demme took 10 drops of a 1/10th alcoholic solution; 21 , Dr. R. E. Dudgeon, provings, from B. J. of Hom., 11, 268; , A. D. (Dudgeon's provings) took 1/10th; , Mrs. A. D., ibid., took 1/10th; , J. J. D., ibid., took 3 pills of 1/10th; , R. E. D., ibid., took tincture and 1/100th; , W. D. (Okie's provings) took 1/250th; , Eichorn, Zeit. d. Ver. Hom. Aezt. Oest., 2, 18, took 3d dec. dil. (10 drops), after two days, the 2d dil., 5 to 30 drops, two days after last dose, took 1st dil., 6 to 15 drops; , Engall (Dudgeon's provings) took 1 drop of 1/10th; , Epps, ibid., 2 globules of 1/10th; , Esry, symptoms only after 1/100th; , H. E. took 1/30th; , F. (Dudgeon's provings) took 1 drop of sat. sol.; , Fellger, preparation not stated; , Field, Med. Times and Gaz., 1858 and 1859, 2 drops of 1/10th and sat. sol.; , Fisher (Dudgeon's provings) 1 drop of 1/10th; , Fiske, Hahn. M., 4, 119, 2 drops of 1st centes.; , (omitted); , Fr. (Rau) took 1/200th; , J. Fr. took 1/20th; , Fuller, Med. Times and Gaz., 1858, took 1/6th of a drop, repeated till 1 drop was taken within an hour; , Gardiner took 1/250th, repeated in ten minutes; , Geist, effects of olfaction of crude oil; , Mrs. Geist, effects of olfaction of 1/100th; , Gellar (Dudgeon's provings), 2 drops of 1/10th; , H. G. took 1/30th; , Süss Hahnneman (Dudgeon's provings) took a small drop of sat. sol.; , Hardenstein, preparation not given; , Hauk took 1/10th, repeated after two days; , W. A. Hawley (H. M., 4, 120), 2 drops of 1st centes. dil.; , Dr. C. Hering, effects of olfaction and different dils., from 1/500th to 1/20th; , Hupfield, various provers, dose never more than 1/1000th; , Jackson took 1/3d of a drop three times, and after some days one whole drop of sat. sol. at once; , Dr. Jeanes took about the 30th part of a drop; , Johns, effects of olfaction during preparation; , Junod (Dudgeon's provings), 6 pills of 1/10th; , S. J., 1/30th of a drop; , K., 1/50th; , N. Koller (Hering), 1/12th; , W. K. took 1/10th; , L. took 1/100th; , Leadham (Dudgeon's provings) took 1 drop of sat. sol.; , Lembke, Zeit. f. H. Kl., 2, 122, took 10 drops of a sol. of 3 grains in 1 drachm of alcohol (=1/6th of Glonoine); , Liebe, effects of preparation, Ann. Ch. Pharm., 109, p. 122 (Hering), 1/100th, 1/250th; , A. Lippe, provings, 1/500th, 1/250th, 1/100th; , Dr. Little, general provings with 1/250th; , M. L. (Lippe's provings) took 1/50th; , omitted; , Mrs. M. (Hering); , N. took 1/200th; , Neidhard took 1/50th; , "O." took 1/250th; and , Dr. Okie took 1/100th; , "P." took 1/25th; , E. P. took 1/20th; , omitted; , Pelouse, Chem. (Hering); , Dr. Phearson (Hering), preparation not stated; , "R." took 1/50th; , M. R. took 1/250th; , Raue took 1/250th; , same took 1/50th; to , Reil and three colleagues (Reil touched tongue to finger wet with pure oil, "A." took 1/100th twice and 1 drop pure, "B." took 1 drop pure, "C." took 1/100th twice and 4 drops pure); , Rhees took 1/125th, 1/60th, 1/50th, and afterwards 1/250th and 1/125th; , Riehle took 1/10th, afterwards 1/50th; , Robertson (Dudgeon's proving), 1 globule of 1/10th; , Roth (Dudgeon), 2 globules of 1/10th; , Roussell (Emma) took 1/10th; , Rr. took 1/500th, 1/250th, and 1/150th; , "S." (Dudgeon) took 1 drop sat. sol.; , S. and F. (Hering); , Dr. S. proving, 1/20th; , C. G. S. took 1/100th, 1/200th; , E. S. (Dudgeon), 1 drop of 1/10th; , J. R. S. took 1/100th and 1/200th; , Mrs. St., 1/200th and afterwards 1/250th; , Dr. Schiek took 1/100th and 1/250th; , a man of 40 took 1/100th; , a girl of 20 took 1/250th; , a man of 33, 1/250th and 1/100th; , a woman of 48 took 1/160th; , a man of 26 took 1/130th; , Schuchardt, action of, Chem. Centralbl., 1866, No. 31; , Small, effects on self and others with sixth centes. dil., 1/200th and 1/300th; , (omitted); , Dr. E. Smith took 1/500th, 1/250th, 1/200th, and 1/150th; , Sobrero, from Hering; , T. Dwight Stow, provings with 1st dil., Hahn. Month., 4, p. 117; , Mrs. M. M., ibid., took 1st centes.; , Streintz, from Hering; , Tafel, ibid.; , Waage, 1/300th, one dose; , Dr. A. E. Wallace, 1st dil., H. M., 4, 119; , J. W. took 1/250th; , J. Wh., 1/50th; , W. P. W., 1/300th; , Dr. Wg. took 1/200th; , Dr. Whitey, 1/20th; , Dr. Williamson, 1/30th, 1/150th; , Dr. J. G. Wood, Am. Inst. Trans., 1/30th; , Dr. Wyld (Dudgeon's provings), 1/10th; and , Zumbrock, effects of olfaction and of different preparations; 1/30th to 1/300th; , Vinal, 1/300th; , ( ); , B. J. of Hom., 18, p. 139, effects on a woman of one globule of Glonoine, 1st.; , Brady, Med. Times and Gaz., 1859, Mar., a chemist took 1 drop of a 5 per cent. sol. for faceache; , V. A. Pierce, W. Hom. Obs., 3, p. 130, took 1 drop first day, 24 drops between 10 A.M. and 1 and 2 P.M., fourth day, 150 drops between 12 M. and 2.30 P.M., fifth day; , ibid., T. M. P. took 6 drops of 1st dec. in evening; , ibid., H. W. W. took 3 drops of 1st centes. dil. (repeated in five minutes); , Dr. Bayes, M. Hom. Rev., 10, p. 107, effects of inserting a bit of cotton soaked in Glonoine 1st, in an aching tooth; , J. M. Merrick, Jr., Am. J. of Sc. and Arts, v, 36, No. 107, effects of vapor and of "minute quantities;" , E. Mystroem, Upsala Lükareförmengs Forhandlinger, ii, p. 232 (Syd. Soc. Year-book, 1867-8), effects of a little; , ibid., a railway workman drank a quantity by mistake; , Honert, Deut. Klin., 1867, p. 83, effects of a few drops for a furuncle; , Holst. Prag. Vierteljhrschft, 1873, a railway laborer swallowed a few mouthfuls from a flask; , Dr. Thorowgood, Med. Times and Gaz., 1858, p. 331, effects of less than 1 drop of 1st dil.

MIND

Emotional.
Unusually animated and talkative; great flow of thought and inclination to jest; for four hours, 121.
Great mental agitation, 117.
Delirious and insensible, and speedily became comatose, 131.
Great depression, 123.
Anxiety (after seven minutes), 57.
Anxiety and inclination to run away, 119.
Anxiety, with headache, 119.
Feeling of impending misfortune, with the sensations in the chest, 99.
Fear and terror, 111. [10.]
Great fear, with a sensation as if the chest were screwed together, 65.
Great fear, with a feeling as if the throat was swollen, 36.
Though naturally cheerful she became apprehensive of her approaching death, 91.
When asked, a day or two after, how she felt, she said, that at one time she was frightened for fear she had been poisoned, and that no one would catch her taking any more, 106a.
Recalls old grievances (second day); he was constantly thinking of persons who had offended him, with determination to justify his own conduct, 116.
Intellectual.
My intellect returned almost immediately, and I remember saying, "This has nothing to do with homœopathy, but with a very powerful poison," 34.
Though still greatly confused, scarcely knowing where he was or what he was about , yet, when his attention was fixed by any effort of the will, remembered his patients perfectly, all their symptoms, and medicines prescribed, without once mistaking, 117.
Cannot collect my thoughts, 12.
Immediate, effect, confusion of ideas and loss of strength, 16 ; with diminished power of tongue, 117.
Confusion of ideas so great that he could not tell where he was, 117.*
A kind of transient bewilderment, followed by a kind of blindness, 50b. [20.]
When the effect (in head and arms), which she exactly described, ceased after five minutes, it seemed to her as if she awoke from a dream; she moved her arms like one awaking from a dream, .

HEAD

Confusion and Vertigo.
Confused feeling, 12.
Confused feeling, with pains in the vertex, 35. [30.]
With palpitation, confusion of the head; flushed, hot face; the eyes looked dim and tearful; pupils not altered; lasting three hours, 62.
Vertigo, 117, 108, 47 , etc.*
Vertigo in the forehead, 38.
Vertigo in occiput, 64.
Vertigo in the occiput, then pain in the vertex, 64.
Attack of vertigo, in the afternoon, 41.
Vertigo when he throws back his head, 113 ; when he shakes his head, 73.
When turning around, vertigo, 41.
When turning to descend from his carriage in the afternoon, he was seized with a sudden and violent vertigo, and would have fallen had he not supported himself by a tree, 41.
Feeling of vertigo and dimness, which, however, soon passed off (after three days), 86. [40.]
Vertigo, with rocking of every object, and reeling of the body, 78.
Vertigo, with nausea, 91, 106, 34, 6, 47, 16.
In five minutes vertigo, with weakness of sight, pains in forehead, and beating in temples, 101.
Vertigo; face red, eyes weeping, pupils unchanged for three-quarters of an hour; after several minutes. (No authority.)
Slight feeling of vertigo (after one minute, first day); increased (fourth day), 125.
No increase of headache, but violent vertigo, with transient dimness of vision, 39, 86.
A kind of vertigo when going into the open air; reeling gait as after a sea-voyage, 109.
Dizziness (fifth day), 125 ; (after fifteen minutes), 126.
Dizzy when shaking the head, 73.

Nux vom . 200 in the evening, after which he improved, 64.

Headache and nausea, with diarrhœa, 100d, 97.
Headache and accelerated pulse (in five persons), 65.
Headache without acceleration of the pulse, with dull heaviness in the head, 100.
The following morning, headache, and much general heat, and expulsion of fetid flatus (a most unusual symptom), 21.
Evenings, continual headache, 30.
Slight headache all the afternoon, 96.
The fulness in the head lasted some time, and was followed by a slight headache, 122. [160.]
Slight headache, and dull heavy pain in the stomach , with a decided feeling of sickness, though without any apprehension that it would amount to vomiting, 34.
Severe headache which seems to impede the breathing (after fifteen minutes), 126.
Intense headache (after four hours), 132.
Violent headache after nausea, then repeated violent vomiting of yellow mucus, 100c.
Headache so violent that he cannot even think to take an antidote, 54.
Headache set in in less than fifteen minutes, slight at first, but increasing in intensity by degrees, until, in an hour and a half, it became almost intolerable; it was accompanied by considerable faintness and exhaustion, intolerance of light and a feeling of great general distress and alarm in addition to the racking pain; relief was only obtained at length by the inhalation of large quantities of Ether, the insensibility produced by which was followed by broken and disturbed sleep, lasting until the following day, which was marked by weakness, exhaustion, and slight headache; these unpleasant symptoms did not finally disappear for three or four days, 129.
The effect ended with a dull headache, which ceased during sleep, 39.
Lessening and increasing of the headache without cause, 82, 81, 38 , etc.
Headache and pulse increase and diminish simultaneously, 11, 31, 98, 104.
The headache returned after one minute, 18 ; after ten to twenty minutes, lasted about thirty minutes, 19 ; headache returned directly after a renewed dose, . [170.]

(after three hours), 50b.

Throbbing of the brain, from within outward, 36.
Feels something rising from right hypochondrium, through the chest to the head, as if the blood were mounting to the head, and throbbed there; immediately, 111.
Throbbing in the head, mostly in the forehead, increased by every motion of the head, 80, 119.* [210.]
Throbbing in the whole head, especially in the temples and over the eyes, with excessive heat in the head; worse when moving, better when sitting still and lying; also relieved by pressure upon it, 48.*
Throbbing and bursting, especially above the ears and in the temples, and I experienced a choking sensation, as if a ligature were tied around my neck which prevented blood returning from the head, 25.
After twenty minutes the pulsation in the head changes to a slight, throbbing headache; the same during exercise in the open air, 81.
Next day, slight throbbing in the head, if he exerts himself or moves more than usual, 104.
Headache becomes throbbing when stooping, 119, 104, 66, 81.
Throbbing in the head during motion, 81, 4, 36 ; most when going upstairs (after thirty minutes), 104, 81, 46 ; at every step on the stairs, 50 ; worse left, 116.*
Throbbing, pulsation, and confusion of all the senses; sensation of balancing, requiring a constant effort to keep the head erect , which inclined to drop as on going to sleep, 16.
At 5 P.M., a slight throbbing headache commenced, and continued with intermissions for about three hours; occasional spells of nausea, with slight but continued congestion of brain till midnight (after one hour), 51.
Immediately, a violent throbbing in the head, especially in the temples; the pain is mostly in the front part of the head, and from temple to temple, 50a.
Throbbing in the head so violent that the pulse could be counted by it (pulse 110), .* [220.]

Nux, Bell., Aconite , nor Coffee relieve, 64.

Headache worse when writing, reading, and smoking, 64.
As soon as the pulse became normal the usual head symptoms subsided also, 104.
The headache ceases over night, 119 ; during sleep, 39. [490.]
Headache better in the open air, 119, 27.
Drinking coffee lessened it, but only after several hours (strong tea lessened effect of watery solution Glonoine better than coffee, 50 ), 119.
Combing relieves the head, 50.
After five drops of Glycerin the headache ceased in five minutes, which with the same dose had lasted seven hours the day before, 99.
Holds the head with both hands, 53.
Sitting with head in hands and elbows on knees, 50b, 51.
Lying down lessens headache, 48.
Pressing upon it relieves the head, 53 ; (three cases), 48.
Headache better during repose, 119.
Is obliged to rest his head, 31. [500.]
Was obliged to sit down during headache, 39 ; abated while sitting still, 50, 48.
Smoking alleviated the headache, 35.
Drinking tea relieved headache, 119.
When throwing back the head he had no pain (after fourteen minutes), 104.
Headache ceases when going to walk, 119, 19, 31.
Cold bathing does not lessen the headache, 50.

EYE

Objective.
Staring, wild look; protrusion of eyes, 47.
The eyes have a lifeless appearance; the provers wink a good deal and look strangely about; blue rings appear under the eyes of many, 100.
Fixed look, 100.
Eyes injected, seemed to protrude; pupils somewhat enlarged, 52. [510.]
Redness of the left eye, as if injected, during headache, 119.
Bluish pallor under the eyes (after three minutes), 100b.
Blue rings under the eyes, 100, 62.
Subjective.
Sensation as if water were running out of the eyes, 108.
Eyes felt warm, while the temperature of the body was unchanged, 107.
Heat in the eyes, with feeling of tension (after one hour and a half), 123.
7 P.M., the headache of the morning increased, removed to the eyes, followed by drowsiness and heaviness of the lids, 107.
Drawing in forehead extends to the eyes and root of the nose, 27.
Pressive downward towards the eyes, 42.
Pressure straight across the eyes (from smelling), 119. [520.]
Pressure deep in the right eye, at 7 P.M., while walking home; for two minutes, 31.
Prickling in right eye, 27.
Eyes feel sore on being moved, 12, 36.
Quivering of the eyes, could not see straight, could not keep his eyes still, 109.
Brow and Orbit.
Pain over the eyes, 116, 12, 27 ; and in the forehead, 11, 27

(after twenty minutes), 19, 51 ; from sides of the head, 13 ; over right eye, 15.

Pain over the right eye, and at the same time over the supraorbital ridges across from right to left (after six minutes), 113.
Pain over the right eye (after one minute, first day); increased (fourth day), 125.
Pain behind left eye and left ear, but not lasting, 27.
Dull pain over the right eye (fifth day), 125.
Dull heavy pain over the eyes; heaviness over the eyes, towards the temples, 75. [530.]
Pressure extends from the forehead to right margo superciliaris, 27.
Pressure in the right orbit, 119.
Pressing headache over the eyes, and sensitive aching in the temples; when pressing the temples it grows misty before the eyes; lasted all day, 27.
Stitches in the right orbit (after six minutes), 119 ; stitch (after seventy minutes), 15.
Twitching pains in the left orbit, 119.
Pain as if sore on the supraorbital ridge, 116.
Throbbing over the eyes, 48.
Beating over the orbits, 72, 48.
Under the right eye and in the bone a strange whirling sensation; later, the same above the eye (several persons), 65.
Lids.
In nearly all who took it the lower eyelids have a dead, dirty look, as if the lower lid were sunken; the eyes are unsteady, wander unsteadily about, 100. [540.]
The lower lids puffed and swelled (after one or two minutes), 39.
The eyes contracted early in the evening, as if by sleep, cannot keep them open, 64.
Sensation of heaviness in the lids, mornings, with difficult awakening, 107.
Heat in right exterior canthus of the eye, 116.
Lachrymal Apparatus.
Lachrymation, 108 ; with hot eyes, 35.
The eyes fill with water; no headache, but throbbing throughout the whole body, most in occiput and neck, 108.

EAR

External. [570.]
Pain below the left mastoid process when pressing upon it, at 9 A.M., 119.
Fulness about the ears, 64.
A tensive pain behind the right ear, which had been felt occasionally for several days, became stronger, 27.
Dull, tensive pain in region of right mastoid process; the painful point can be covered with the end of the finger; no effect from pressure, but worse after pressure, 27.
Pressing tensive pain behind the right ear; worse during, but especially after, pressure; pressive pain in the right ear, as if swollen; tension in the right temple (some days before taking

Glonoine , pain had been felt behind right ear), 27.

Piercing pain from the region of the right ear towards the right eye (twenty minutes), 53.
Especially above the ears , throbbing, 25.
Internal.
Fulness in the ears, 57 , head, 27 , and nostrils, 30.
Fulness worse in left ear, 30.
It darts to his ears; it feels as if stopped up in the inner ear, 81. [580.]
Stitch in the right ear (after thirty minutes), 31.
Stitches in the ears, alternately, with pressure in the forehead, 27.
Dull stitches in the right ear, 27.
Dull stitch alternating in right or left ear, 27.
Throbbing pain, piercing from within outward, in the right ear, 50.
Hearing.
Heaviness, deafness, and sensation of being stopped up , in the ears, 64.
Partial deafness, followed by indistinctness of vision, 51.
Buzzing in the ears, 129.
When the headache was very violent, a fine buzzing began in the left ear, and redness of the left eye as injected, 119.
Crackling in the left ear (three or four minutes after), 53. [590.]
Ringing in the ears , and audible pulse, 96.
Rushing noise in the ears like escaping steam, 34.
Humming in the ears, 86b.

NOSE

Objective.
Thickening of the Schneiderian membrane, as in dry coryza (after two minutes), 126.
Sneezing, without increase of headache, with running of the nose, 50.
Late in the evening sudden sneezing and fluent coryza, 50.
Stoppage of the nose, as in a cold (after two minutes); increased after second dose, 127.
Subjective.
Sensation as if both nostrils were stopped up at the root of the nose, 74.
Pain over the nose and in the petrous portion of the temporal bone of the right side, 4.
Dull pain in the root of the nose, 82. [600.]
Twitching pain in the root of the nose, right, 119.
Twitching in the wings of the nose, and prickling-twitching in the face, 18.
Darting, twitching pains in the right side of the root of the nose and right side of forehead (after one hour and a half), 119.

FACE

Objective.
Redness of the face, 66 , and others.
The face grows red, especially in the upper part of the cheeks, and still more in the lower eyelids, likewise the ears, but not the forehead, 11.
His face grew red, his temples throbbed, his pulse increased from 80 to 112; he felt a weariness, like a weight over his eyes, whence it extended to the temples; he began to yawn, and yawned every moment; felt sleepy; shaking the head made the head worse; lasting several hours, and ending with a dull, heavy pain over the eyes (after one to two minutes), 75.
Redness of the face, and fear, during headache, 119.
Face grew red during headache, 75.*
Face alternately flushed and pale, 106b.
Blue in the face (after one hour); face afterwards red and swollen, 131. [610.]
Pale face, 51 ; after sweating, 112.
Countenance pale and agitated, even after a long time, 17, 91, 112.
Pale face with nausea and congestion to chest, 50b.
Face pale, or at times a little flushed; at times a livid hue, 47.
Afterwards looked remarkably pale in the face (unusual for her), complaining of extreme languor and heaviness in the limbs, 91.
Since he took the medicine he has looked remarkably pale, and although not complaining of anything, had a fainting fit, in the evening, after returning from his drive (is a coachman), which threw him down senseless, 17.
Subjective.
Feeling of heat in the face, as if sitting by a hot stove, 49.
Face feels hot, full, and bloated, 110.
In five minutes slight heat in the face; this was followed by a painless throbbing in the head, beneath the os frontis , and extending entirely across the temples, 51.
Sensation of flying heat, rising from the chest to the face and heat, 38, , . [620.]

MOUTH

Teeth.
Slight pain in the lower molars, worse right (after thirty-two minutes); worse in the left molars (after forty-seven minutes), 50.
The headache was accompanied by toothache, and drawing in all the teeth, right, as if after taking cold, alternating in the ear and lower jaw, 119.
*Throbbing pain in all the teeth, 102.
Tongue.
Tongue somewhat numb, 50.
Tongue white and enlarged, with indentations of the front teeth (third day), 116.
Tongue feels as if enlarged, and is coated white, 116. [650.]
Tongue feels swelled and raw, with spasmodic twitchings, 52.
Stinging in the tongue near the centre and tip, 106.
Biting, pricking, and burning on a small spot on the left side of the tongue, as if the spot were sore, 50, 4.
Pricking-biting on the tongue, as severe as if he had bitten it sore, 50.
Pricking on the tongue, a chilling, burning sensation, 50.
Almost immediately after taking the medicine, I felt a pricking on the tongue and in the fauces, with beating and throbbing in the vertex and through the temples, and slightly in the occiput; the latter sensations came in paroxysms, and were worse on movement, 4.
Prickling sensation on the left side of the tongue near the tip (after three minutes), 3.
Prickling in the point of the tongue, left, lasting several seconds, 69.
Tongue and mouth as if burnt, 52.
General Mouth.
Pimples on the inner right cheek, 9. [660.]
Mouth dry and clammy, throat dry, and painful during empty swallowing, 58.
That night I could scarcely sleep for excessive dryness and parched feeling in the mouth, with great thirst, which, there being no water in the bedroom, I was unable to quench; this symptom was still present when I rose in the morning, 25.
Mouth feels parched, 25.
Burning sensation in the hard palate (second minutes), .

Chloric ether, 40.

Taste slightly like Ether and aromatic; it left a fatty taste in the mouth, 53. [680.]
Scratching, piercing, cinnamon-like taste, 50.
The taste after 1/10th drop of pure Glonoine was piercing, sharp, and aromatic, something like cinnamon, 19.
Taste in the mouth like pine wood (after twenty minutes), 116.
Taste like pine roots, 88.
Remarked a fatty taste, but at the same time an aromatic one, like cinnamon, 113.
The taste seemed to him fatty, 56.
Taste sharp, disgusting, fatty, 119.
Oily, disagreeable taste in the mouth (tenth minute), 121.
Taste sharp and very tenacious, 95.
Sharp, scratchy taste in pharynx, 112. [690.]
Biting, sharp taste, and prickling on the tongue, 50.
Speech.
Great difficulty in conversing, from diminished power of the tongue and confusion of ideas, 117.

THROAT

Thick mucus in the throat, 64, 116.
Throat dry and painful during empty swallowing, 58.
Sensation of heat in throat next day, and several days after, 64.
Sharp burning in throat, 30.
Feeling of fulness in throat, 28.
Fulness, as if swelling in her throat, 91.
Momentary sensation as if the throat were swelling, and fear , which caused her to feel of it constantly; she thought others must also be able to feel it, 100.
Choking sensation in the throat, 123. [700.]
Tight and choky feeling about the throat, like strangulation, followed the tensive headache, 134.
During the night, with continued dryness of the mouth and throat, and headache, feeling of choking at throat, and frequent inclination to swallow, 21.
Tingling sensation in the throat, and increased saliva, 20.
Awoke at 2 o'clock in the night with a sensation like tickling, and pain at the same time as if something sharp, like a rough feather, were being drawn up his throat; it caused coughing; ceased after drinking water; had the same once before, 31.
Sharp tickling in the throat, 19.
Soreness in the throat, 65.
Uncomfortable sense of irritation in the throat, 130.
Slight roughness in the throat (after fourteen minutes), 104.
Pulsation in the neck, fulness in the head, throbbing in the temples, and slight nausea, 34.
Uvula and Tonsils.
Great dryness of the soft palate, more towards the back, and downwards (first hour), 53. [710.]
Contractive sensation in the soft palate, 82.
Sensation as if the soft palate were drawn up, 82.
Sweet taste, itching of the soft palate and throat , and frequent need to spit; the itching increased in severity, until it became unbearable, and spread over the whole surface of the throat, 107.
Stitches in the left tonsil, .

STOMACH

Appetite.
Increased desire to smoke , and the smoking regulates the bowels, 119.
One who took a cold (coryza), and could not smoke, but as soon as he had taken

Glonoine had a great desire to smoke, 119.

Entire loss of appetite, though strong five minutes before taking the drug, 117, 75.
Thirst.
Thirst, 123.
Desire to drink cold water, with nausea and faintness, 39.
Eructation.
Eructation, 116, 50 ; with taste of Glonoine (after ten minutes), 31.
Eructation before the headache, 119.
One or two heavy, long, but easy eructations, 106.
Belching of wind from the stomach, 51 ; with feeling of pressure at pit of stomach, 110. [730.]
Flatus from stomach, 28.
Regurgitation of the food (after fifteen minutes); supper did not digest well, 126.
Nausea and Vomiting.
Nausea (after third dose), 86, 123.
Nausea for an hour, 100.
Nausea, with pain desire to vomit, but inability to do so (fifth day), 125.
Nausea, with pain in the stomach, 27 ; with headache, 41, 42, 21, 91, 64.
Nausea, and pain in the stomach , with rumbling in the intestines, 11.
Nausea, accompanied by congestion of brain and lungs, 51.
Nausea, with congestion to the head and chest rapidly increasing, face pale, 50 ; with headache, better in open air, 106.
Attacks of nausea, with congestion to the chest and head, till midnight, 50b. [740.]
Kind of nausea and bitter taste (after twelve minutes), 115.
Great nausea (after four hours), 132.
A feeling of sickness and pain at the epigastrium came on shortly, and he left his desk to pace about the shop, thinking to walk the uncomfortable sensations off; instead of this they grew worse, .

ABDOMEN

Hypochondria. [770.]
Blood seems to rise from the left hypochondrium, 111.
Pain at a small spot in left hypochondrium, 28.
Pain in the left hypochondrium , half way between the pit of the stomach and side, 116.
Violent piercing pain in the left hypochondrium, the following morning, 98.
After two hours I felt, while standing, an extremely violent shooting pain under the ribs in the right side (region of gall-bladder), that caused me to bend forward while it lasted, which was about half a minute, 25.
Umbilical.
Pinching around umbilicus, 28.
Pain in the abdomen, cutting under the navel, the following morning, lasting several days, 31.
Sinking beating in the aorta, behind umbilicus, 106.
General Abdomen.
Peristaltic motion retarded, 132.
Rumbling and bursting of flatus in middle and lower abdomen, 106. [780.]
Rumbling in the abdomen mornings, with diarrhœa, 121.
Rumbling in the abdomen, with pain in stomach, 11.
Rumbling in abdomen, belching of wind , loss of appetite, 58.
During stool, after 10 P.M., a rumbling and growling began, more in the lower abdomen as in diarrhœa, grew worse in bed, still worse when lying on the left side and lasted till going to sleep, 31.
Rumbling in the bowels as in flatulence, with feeling as if diarrhœa were coming on; also prickings in the pudenda, and a feeling of dryness and parchedness in the throat, 21.
Rumbling in the transverse colon, 116.
Flatus in the abdomen all the evening, 116.
A quantity of flatus from the rectum, 28.
Frequent passage of flatus during stools , with a loud sharp noise, 116.
Offensive flatus, giving relief, 107. [790.]

RECTUM AND ANUS

(Hæmorrhoids), 48.
During evacuation the anus seemed more contracted, closer than usual, 116.
The urgency to stool could be very easily suppressed, 116.
Inclination to diarrhœa before proving had disappeared the next morning, but returned the third morning, 1.

STOOL

Diarrhœa. [800.]
The following day he had diarrhœa, copious, loose, blackish, lumpy, 118.
Diarrhœa in the morning, with sharp burning, 119 , with rumbling, 121.
After eating peaches in the evening, diarrhœa during the night, 96.
Diarrhœa and vomiting lasted without interruption for an hour and a quarter; the vomited matters still smelled strongly of the poison. Motions at first greenish and then frothy, had a similar smell, 133 . [The diarrhœa and vomiting may have been the result of the emetic.]
Diarrhœa, with sudden cessation of the menses, 21.
Slight diarrhœa in the morning (after fourteen hours), with much rumbling in the abdomen and passage of flatus (after nineteen hours), at 1 P.M., 121.
Several thin stools after vomiting and diarrhœa, 100.
After luncheon, 2 P.M., a copious, loose motion; later, while driving about, griping pain in the rectum, and urging; I succeeded in restraining this until 6 o'clock, when I was forced to return home, and my bowels were moved; the evacuation was loose but not copious; it seemed as if much more were to come, but that there was an obstruction high up in the rectum; before the evacuation I felt sickish and faint; the urging was less felt while driving in the open air than in the warm room; after dinner I had another loose, scanty evacuation, after which all the symptoms went off, 25.
Copious evacuation of very soft fæces (one hour and thirty minutes after second dose, and three hours after), 116.
Thin stool and nausea, with headache, 42.
Constipation. [810.]
Constipation and hæmorrhoids, which itched and pained ( , or accidental), 48.
After 10 in the evening, an unaccustomed time, a hard and unusual stool, pinching in the abdomen before and after it till going to sleep, 31.
No stool; something very unusual, 116.
No motion in the bowels two days afterwards, 46.

URINARY ORGANS

Micturition.
Abundant urine, containing large quantities of albumen, 64.
In congestion with unconsciousness, it causes unusual evacuation of urine, 64.
Considerably increased passage of light urine the following day, and continuing for a week, in one who had scanty evacuations of urine for months, 64.
Much yellow and frothy urine, voided painlessly (second day), 106.
Urine.
Urine high-colored, causing a sensation of burning and heat in the urethra, while passing it (third day), 58.

SEXUAL ORGANS

Sensation in the genitals, as after repeated coitus, without weakness, 50. [820.]
Prickings in pudenda, 21.
The catamenia ceased immediately, and the headache increased in violence towards evening, when severe diarrhœa came on; the catamenia did not resume their flow until the following morning on walking briskly, 21.
The next day the catamenia, which had ceased six days, returned profusely, and lasted for the usual time; she had never experienced the same accident before; but I am by no means certain that it is attributable to the Glonoine, for three days previously she had taken a hot bath at a much too elevated temperature, which had caused her to feel faint and weak; yet she had never before been injuriously affected by warm baths at a high temperature, 21.

RESPIRATORY ORGANS

Larynx, Trachea, and Bronchi.
Rattling of mucus in the air-passages (after four hours), 132.
Undefined sensation in the region of the larynx, and in the articulation of the jaw, and below the larynx, 38.
Sense of constriction in the larynx, obliging one to swallow (fourth day), 125.
Constriction at top of larynx, 36.
Spasmodic constriction of the larynx and upper portion of the trachea (fifth day), 125.
Prickling sensation in the epiglottis, 57.
Cough.
Cough from tickling in throat, 31.
Respiration. [830.]
Breathing stertorous, 34.
Offensive breath, 121.
Inclination to deep inspiration, 107, 64, 116.
Frequent urgency to deep respiration, 64.
Inclination to sigh, 99 ; (after several minutes), 80.
Deep heavy respiration, 50b.
Superficial breathing; no inclination to deep respiration for half an hour, 64, 99.
Breathing very superficial, with occasional deeper inspiration (after six hours and a quarter), 133.
Respiration free, although the chest feels as if contracted, 52.
Breathing accelerated, 110 ; 16 per minute; respiration more rapid and the pause after it longer, 50. [840.]
Respiration diminished (after four hours), 132.
Breathing oppressive, respirations decreased from 19 (normal) to 11 per minute (fifth day), 125.
Shortness of breath and oppression of the chest, with inclination to sigh, 99.
With decrease of headache, shortness of breath and oppression of the chest, 99.
Difficulty of breathing lasted several minutes, then throbbing and pain in the head returned, .

CHEST

Congestion to the chest and head (twentieth minute), 50b.
Mucous membranes of the chest again become sensitive to the fumes of chlorine and nitric acid, 54.
Uneasiness in the chest, 7.
Indescribable sensation in the chest, as if some misfortune were impending, 41. [850.]
Disagreeable, nervous sensation of uneasiness in the chest, 7.
Feeling of fulness through the chest, 110.
A fulness begins in the chest, and rises to the head , throbbing in the head, and a sensation as if the skull were too small (in five persons), 65.
Pain in the chest like tension, and frequent inclination to deep respiration, 64.
Contraction of the whole chest, as if chains were being placed around it, and tightened more and more, 111.
Sensation of constriction and oppression of the chest , with perceptible palpitation, compelling to draw the breath deep (after two minutes), 107.
After throbbing headache, a compression of the chest as if he had worked too hard, as if a spasm constricted the chest; lasted two hours, 50c.
A feeling of tightness about the lower part of the chest, 110 ; as if the chest were being screwed together, 100.
In the chest, left, "incipient headache," 65.
Sensation of oppression at the chest (after one hour and a half), 133. [860.]
Oppression of the chest, causing deep and heavy respiration (fifth minute), 50b, 51.
With throbbing of temples, oppression of chest, 50, 99.
Oppression of the chest as if laced together , and no headache, in one who formerly had heart disease, 65.
Felt as if there were a heavy weight upon the chest (fifth day), 125.
Occasionally sharp catching pain under the left ribs (second day), 46.
Sharp, cutting pains in the chest and stomach, with sickness, griping pain in the bowels, and an inclination for an action of the bowels, which lasted till the next morning, when the bowels were relieved, .

HEART AND PULSE

Præcordium. [870.]
Felt the remedy first in the heart, and later in his head, 73.
When he feels it in his head, he perceives it less in his heart, and thus alternating, 73.
Feels his heart beat (after four minutes), 95.
Can count the pulse by the heartstrokes, 110.
Sensation of weakness in præcordia, 106.
Sensation as if about to have an attack of palpitation of the heart, as he had formerly had, 41.
For three months, anxiety about the heart after dinner when leaning black in chair (Nat. mur. helped), 42.
Evenings, after lying down, an anxious sensation about the heart, with throbbing; a purring noise and intermittent pulse; was obliged to lie with his head high; insufferable when lying on left side, better when lying on the right side; ceases after rising and walking about, 42.
Great anxiety in the præcordial region (after third dose), 86.
Sensation of heaviness and disagreeable feelings about the heart, 52. [880.]
Heat in the heart, 69.
Sensation of fulness about the heart, almost increased to pain; it seems as if it would rise to the throat; pulse decreased from 72 to 64, 42.
Undefined aching in the heart, followed by sensation of heat and warmth, 69.
Pressure in the heart and as if it were being contracted, 65.
Oppression of the heart, with heat in the forehead, 114.
Sharp pains in the heart, lasting two minutes (after ten minutes), 57.
Sharp stitches in the heart, 110.
Shocks about the heart, with pricking pains in the hands and arms, 110.
Heart's Action.
Increased rapidity of the heart's action, with nausea, 21.
One prover, after one drop, was affected with great increase of the rapidity of the heart's action, violent throbbing in the head, followed by faintness and sickness, terminating in retching, but not coming to actual emesis, . [890.]

NECK AND BACK

Neck.
The muscles of the neck seemed to weary so from constant headache, that at last he could scarcely hold up his head, 119.
Stiffness and pain, left, in back of neck, 116.
Indescribable sensation up in the back of the neck, verging on pain, 18.
Pain extending to the back of the neck, 73, 27.
During night, pain in nape of neck, lasting until next day, when headache followed (aching all over), with giddiness; better after drinking tea, 108.
Considerable pain in the back of the neck, soon, 133. [970.]
Severe pain in the cords of the neck (after two minutes), 127.
Dull pain up in the back of the neck when moving the head (after fifteen minutes), 82.
Sensation of fulness, as of congestion to the back of the neck, throat, and head, 95.
"I laughed at my friend's credulity, and offered to take as much as he chose to give me; in about three minutes (after two drops of 1st dil.) a sensation of fulness in both sides of the neck; to this succeeded nausea, and I said 'I shall be sick." 34.
Tensive pain extended deep into the sides of the neck; not increased by moving the neck, 27.
Tightening around neck, 34, 25, 122.
When throwing back his head, he felt a pain like a cramp in the back of his neck , to the left, in the region of the sixth and seventh cervical vertebræ (after three minutes), 104.
Throbbing in the neck and arteries of the brain, 52, 25, 119.
Throbbing extends to the back of the neck, 119.
Unpleasant throbbing in the arteries of the neck and head, and extending rapidly to the temples and forehead, 83.
Back. [980.]
Constriction in the chest was followed by a pain in the spinal column, down the entire back, 50c.
Afternoons and evenings, acute pain in back, especially in the region of the lumbar vertebræ, .

EXTREMITIES IN GENERAL

Great weakness in middle portion of thighs and arms, 16.
Sensation of weakness and trembling in the limbs, 26.
The limbs on which I lay went to sleep directly (third day), 58. [990.]
The feeling in the limbs passed off with a whirling sensation, 26.
After repeatedly exposing himself to the influence of the drug, an uneasiness was caused in every limb, which impelled him to rise as often as he sat down, 119.
Her extremities feel bloated, 106b.
Sharp, pricking pain in the arms and legs; cramp in the right leg, 28.
The very first sensations after taking the medicine went from below upwards; but after two minutes, from above downward into the arms, and thence farther into the knees, 53.

SUPERIOR EXTREMITIES

Slight weakness in arms and hands, 51.
She could not raise her drooping arms for several minutes, 50c.
Sensation of weakness in the arms and hands, 50b.
Disagreeable, nervous sensation of uneasiness in the arms and hands, so that he is obliged to turn and twist them, 7.
After throbbing headache, a sensation of numbness in both arms, and a heaviness in them which made moving them perceptibly difficult; this lasts as long as the throbbing headache, 50c. [1000.]
Numbness , and a sensation of weariness in the left arm , so that it requires a great effort to raise the arm (with stiffness in the middle joints of the fingers), (in several persons), 51.
Heaviness in the arms, as if circulation were checked, or as if the arms were going to sleep, 81.
Dull pain in the arms, as if in the bones (third day), 38.
Shoulder.
Pain in left shoulder, 50.
Pain across the shoulders, which soon extended to the arms, and was especially violent on the back of the right hand, at the finger end of third finger metacarpus (after two minutes), 53.
The headache extended over the shoulders and down under the arms, 50c.
Drawing through the shoulders, 110.
Elbow.
The left elbow feels weeks, and aches, 12.
Painful sensation in both elbows, especially in the right one, in the hollow between the inner condyle of the upper arm and the olecranon, where the cubital nerve descends; first left, then right, more violently right, but still painful left, after the pain had ceased (after twenty-nine minutes); similar pain in the elbow, but on the exterior margin, 11.
Contracted sensation in the right elbow, 116.
Wrist. [10.]
In right wrist a feeling as if it were tied up, which produced a kind of lamed feeling all along the right arm, 46.
Hand.
His hands, especially the left one, begin to tremble and grow cooler, .

INFERIOR EXTREMITIES

Twitching of muscles of lower extremities, 20.
Cracking in the right hip and knee, then in the left, 53. [1020.]
As if overtired in the lower limbs after walking a few steps, 26.
Going to sleep of the legs when sitting, 64.
Hip.
When walking a cracking in the right hip-joint twice, and soon after, twice in the right knee (third minute), 53.
Thigh.
Weakness and numbness in the left thigh and leg, which began to lessen from above downward, and remained longest in the foot, on the lower half and exterior side of the tibia, at the ankles and in the toes, 26.
Sensation of weakness in the left thigh, and a pain from the buttocks to the heel, on the interior side, along the course of the ischiatic nerve, most violent in the calf (second day), 99.
As if the thigh were giving way, would break down under him, for three hours (second day), 99.
The felt thigh as if gone to sleep, 26.
Knee.
Crackling in the right knee while walking (seventh minute), 53.
When she tries to bend the knee a loud, painful cracking ensues; for several years, since a fall on the patella; dose every fortnight, 8.
The left knee feels weak and aches, 12. [1030.]
Pain in both knees under the patella, not in the tendon, but on both sides of it (after three and four minutes), 53.
Pain under the left patella, 116.
Slight pain below right knee, 13.
Sharp pain in left knee, 13.
Leg.
Pain in the left leg below the knee, 12.
Pain worse in the calf, 99.
Pain deep in the left calf, of long duration, 50.
Foot.
Burning-itching pain externally on the right heel, worse downward and inwardly, .

GENERAL SYMPTOMS

Objective.
Excessive excitement of the vascular system, and forcible palpitation, 132.
Congestion, with nausea, 50b. [1040.]
I learn from the physician, to whom I am indebted for this overdose (2 drops of the 1st dil.), that my head fell backward, my jaw dropped, I was perfectly white, breathing stertorous, and no pulse at the wrist for the space of about two minutes, 34.
After three hours, walk vacillating, increasing palpitation; with palpitation began slight pain in head, pressure here and there , especially in occiput, wearisome, growing less till 9 P.M.; at 5 1/2 o'clock feeling better, but face remained looking pale and sickly, with blue rings under eyes, 62.
Could neither lie, sit, nor walk, but pitched about like one intoxicated, incapable of controlling the muscles of locomotion, 117.
Tremor, sopor, and lassitude, 106.
Cold water now poured upon the top of the head produced spasms, which ended in vomiting, after which (7 o'clock) became comparatively easy for a few minutes; very soon, however, pressure and throbbing in the brain returned, and continued to increase till a second vomiting, followed, as before, by a considerable relief for a few moments, after which the throbbing and pressure again returned, followed by a third vomiting; a cup of warm tea, now taken, seemed to afford decided relief, relief, however, of but short duration; took

Camphor at 3 o'clock, and Belladonna at 5 o'clock, but without any relief; after this, slow recovery after several days, 117.

Complete paralysis of all the voluntary muscles; the muscles of mastication and of the face and eyes were only partially paralyzed, 132.
Strength much affected, 11.
General languor, 111, 13.
Languid, but conscious at the same time that I could exert myself, 34.
Great lassitude and weariness in the limbs, dull pains in the arms, tingling in the fingers, 58. [1050.]
Next morning weariness, as after a night's debauch, 51, 13, 106, 111.
Weakness and apathy, 106.
Weak and tremulous (second day), 106.
The way home seemed three times as long as usual, 19.
Faintness and exhaustion, 129.
Faintness before nausea, 39.
Faintness and fainting also during headache, 42.
Fell into a chair and said his strength had left him; grew faint and deadly pale; could not see, but did not lose consciousness, and moved when he was jostled; for ten minutes, 50d.
She became partially insensible, disliking very much to be aroused; when fully sensible she felt headache, 34.
In about five minutes, after feeling giddy and sick with headache, she became insensible, 34.* [1060.]
He had barely time to call his assistant, when he fell back insensible; cold water was freely dashed over the face, and the unconsciousness soon passed away, 124.
In a minute he said he should faint; almost instantly his knees gave way; he fell senseless on the pavement; it was noon; he lay breathless a minute or more, drawing at long intervals a deep sigh, face pale; came to consciousness in two minutes; perspired some; excessively faint and sick at stomach, cold hands and feet, pulse feeble; could not allow his head to be on a level with his body, but must have it elevated ; it felt full; could not see objects distinctly; dizzy, face pale, or at times a little flushed, at times a dark, livid hue, sickly; motion aggravated or augmented the symptoms very much; Belladonna did no apparent good, Camphor relieved some; at 5 o'clock still somewhat cold hands and feet; previous to this, hot foot-baths relieved him very much; took him to Walnut Hills in a carriage; vomited on the way twice, produced by the jostling of the carriage; left him at 5 o'clock tolerably comfortable in bed; any motion increased nausea and head symptoms very much; pains in occiput, stitches; frequent yawning after some hours; ; on the fourth day still ailing; took black coffee, which relieved immediately all suffering, and continued so; after twelve days, still feeble and nervous, and sore mouth, .

SKIN

Since taking the medicine has a rash on her face after washing; this symptom she never had before, 91.
Sensation as if cold sweat were on the forehead and temples; but there was none, 86.
There passed from the head, down through the shoulder, into the arms to the tips of the fingers, and then through the whole body to the soles of the feet, a kind of crawling, and like magneto-galvanic currents, 109. [1100.]
Constant inclination to rub the forehead ; he had a crawling sensation there, 53, 100.
Itching on the face, 18.
Itching on the back, 50.
Itching of the hands, 18.

SLEEP AND DREAMS

Sleepiness.
Yawning and inclination to deep inspiration, 116.
Yawning, and inclination to stretch backwards, 18.
Frequent yawning, 28 ; after several hours, 47.
Constant yawning during congestion to the head, 75.
Sleepy, 50, 11

(several persons), 51, 110, 106b , at 2 P.M. (second day), for two days, 106.

Sleepy, hot face, and paler than usual, 80. [1110.]
During headache, a drowsy stupid feeling, as if the head were too heavy, 48.
Sleep, with congestion to the head, 75.
Slept better than usual the second night, 116.
Slept unusually well that night, and experienced no ill effects in the morning, 86b.
Immediately fell into a heavy sleep, 117.
Heavy, but restless and unrefreshing sleep the whole afternoon, 86b.
Restless sleep on account of the pains, but very heavy morning sleep, although habitual, more than usual, 35.
Night sleep as usual, and even till nine o'clock in the morning, 119.
Difficult waking up in the morning, eyelids heavy, 9.
Difficult waking from deep sleep, and difficulty in getting aroused on being called at the usual time; after getting up he remains as wakeful as usual, 31.
Sleeplessness. [1120.]
Restless sleep on account of the pains, 35, 27.
Wakes very early the following day, 11.
During the night felt very restless an unable to sleep, thirsty and hot, and inclined to vomit, 97.
When falling asleep wakes up with fear of apoplexy, 119.
Cannot sleep; awakes in fear of an apoplectic stroke, 50.
Dreams.
Dreams in the morning, 31.
Wild, confused, and unpleasant dreams, 86b.
The unusually early sleep was full of dreams, till finally a dream of homesickness, which moved him to tears, 107.
In the morning remembers dreams about people who were moving grain and clover, 31.
During the early part of the night my sleep was disturbed with visions of innumerable multitudes of heads , with comical expression to the features; awoke about 3 A.M. without being much refreshed; in about two hours I slept again till morning, 44.

FEVER

Chilliness. [1130.]
Congestion to head causes sensation of coldness, 30.
Cold feet (second day), 123.
Cold feet, with palpitation, nausea (B. J., vol. 18, p. 139).
Limbs deathly cold (after four hours), 132.
After stooping, a cold shudder runs down the back, and after continued walking, some flushes of heat follow (after ten minutes), 52.
Heat.
Sensation of warmth through the body, 100b.
Sensation of warmth and heat (several persons), 51.
General warmth , through the whole body, 100 , especially of head and face, 50, 69.
Strange, weakly, warm sensation over the whole body; more when standing, less when sitting, with flushes of heat to the face and dizziness in the forehead, 34.
General heat (after three minutes), and moist skin (after six minutes), 79. [1140.]
Heat, with profuse sweat for a quarter of an hour (immediately after taking one-sixth of a drop), 62.
One evening after smelling the tincture, felt heat all over the frame and perspiration in the hands , to which he was never subject, 1.
Heat, with fulness of the head, 50, 66.
Immediately, great heat throughout the body, especially in the face, with copious hot sweat, lasting a quarter of an hour, 62.
With the headache the inner heat increases, but the skin is not dry nor sweaty, 50.
Flushes of heat, 81, 82, 34.*
Hot flushes over whole body, with feeling as though the whole surface would break out in sweat, continuing for hours, 34.*
Sensation of warmth and fulness as if in the sciatic nerves; warm, dull aching in loins for a short time, 46.
Felt a sensation of warmth and fulness down the arms, as if in the course of the cutaneous nerves; also a similar sensation in the sciatic nerve, and some warm, dull aching in the loins; but these symptoms lasted but a very short time, .

CONDITIONS

Aggravation.
( Morning ), When stooping, stitches in head; heaviness in eyelids.
( Afternoon ), Headache.
( Evening ), Pain in forehead; pain in vertex; headache.
( Open air ), Vertigo; headache.
( Ascending stairs ), Throbbing headache.
( Change of position ), Headache.
( After dinner ), Headache.
( After eructation ), Headache.
( Holding breath in open air ), Headache.
( Looking long in one direction ), Pain in forehead.
( Motion ), All symptoms; throbbing in temporal regions; pressure in vertex, etc.; after rising, pain under vertex; sensation in sides of head; headache; nausea, etc.
( Moving head ), Symptoms of head, etc.; pressure in head; throbbing in head; headache; headache in temples.
( Pressure ), Headache; pain behind ear.
( Reading ), Headache.
( Rest ), The symptoms.
( Rising ), Blindness, etc.
( Rising suddenly ), Headache, etc.
( Shaking head ), Dizziness; pressure in head; soreness in head ; headache, etc.; pain in forehead; pain in temple; pain in occiput; headache , etc.
( Shaking head lightly ), Dullness of head.
( After shaking head ), Fulness in occiput.
( Smoking ), Headache.
( Standing ), The symptoms; pain under vertex.
( Stepping ), Soreness under vertex; headache.
( Stooping ), Sensation in head; darting in head; stitches in head; soreness under vertex; ; black spots before eyes, etc.; palpitation; pain in region of heart.

SUPPLEMENT: GLONOIN. Authorities. ( 135 and 136 , from Berridge, Hom. World; vol. xiii, p. 401); 135 , Dr. George Harley, Med. Times and Gaz., 1858, vol. xvi, p. 356, experiments; 136 , Mr. F. A. James, ibid., p. 383, experiment; 137 , Allinson, Times, July 31st (Pharm. Journ., 1866-7, p. 263), a man drank a quantity; 138 , Conrad Wesselhoeft, M.D., North Amer. Journ. of Hom., New Ser., vol. vii, 1876, p. 6, experiments.

I touched my tongue with the cork moistened with the 1st cent. dil., but experiencing no effects beyond that which usually follows the application of Alcohol or Ether to the tongue, I put 2 drops into my mouth: At first I felt a kind of sweet and burning sensation, and soon afterwards a sense of fulness in head and slight tightness about throat, but without nausea or faintness. In a minute or two these effects went off, and could not help thinking that they were partially due to imagination. I now took 5 drops more, and as these did not cause any increased uneasiness, I took in the course of a few minutes 10 more drops. Being at the time quite alone, I became somewhat alarmed lest I should have taken an overdose, and very soon my pulse rose to above 100. The fulness in head and constriction in throat I thought were more marked than before. In a minute or two my courage returned, and the pulse soon fell to 90. The fulness in head lasted some time, and was followed by a slight headache. I took a drop of pure Glonoin by degrees, and found that on bringing it in contact with the tongue it at first gave rise to a sweet flavor, which was rapidly followed by a most disagreeable acrid burning sensation, lasting several minutes. Immediately after taking the drop the pulse was 105. I imagined, too, that I felt fulness in head and some tightness about, throat; but as the effects gradually passed off in the course of a few minutes, I thought they were most probably due to fear and imagination. March 29th, at 12.45 P.M.; my pulse being 80 and my breathing 22, I took a solution containing 1 part of Glonoin to 6 3/4 of spirit, a quantity equal to 1/6 drop of pure Glonoin. At 1 P.M. pulse was 90. I felt some fulness in head and slight tightness about throat. At 1.5 P.M. I took 1/3 drop of pure Glonoin. In three minutes more pulse was 98. At 1.16 P.M. I took 1/2 drop, and in four minutes afterwards, my attention having been directed to another subject, the pulse was 94. At 1.30 P.M. I took a drop of pure Glonoin, and in six minutes the pulse was 106. In ten minutes more, when I had become convinced that I ran no risk, the pulse fell to 78, the breathing being 18. The effect on the heart's action I consider to be entirely due to fear. The head and neck symptoms are too constant to be attributed to the same cause, though I have no doubt the imagination exaggerates them, 135.

I took a minim of Glonoin, my pulse being 80. Half an hour before I had seen my brother take the same dose without any serious effect, and we now purposely changed the subject of conversation. In the course of a few minutes I exclaimed, "I feel drunk." This sensation was quickly followed by a dull aching pain at back of head, which was alternately better and worse, each accession becoming more and more severe. It soon extended to the forehead and the back of the neck, in which there was a decided feeling of stiffness. There was also some difficulty of swallowing, succeeded by nausea, retching, and flatulence. A profuse perspiration ensued, and in fifteen minutes the symptoms began to abate, but I continued dull and heavy. My pulse was now 100. Considerable headache remained, which increased in the afterpart of the day to such an extent that, at 6 P.M., I was compelled to go to bed. At daybreak I was not relieved, but after a few hours more sleep I arose in my usual health, 136.
Was instantly seized with great pain, and his body became diffused with a dark-blue tinge. The unfortunate man only survived a few hours, 137.

The Glonoin used was the dilute nitroglycerin of commerce in proportion of 1 to 80.

Table I.

Table I.

Six provers first ascertained their normal pulse, then excited it by running at their utmost speed for about five minutes out of doors; immediately on returning to the room each prover's pulse was counted by another person, and at the same time, just as the counting began, four provers each took a drop of Glonoin in a teaspoonful of water. In five minutes the pulse of each prover was again counted; the result, as exhibited by the table, shows the pulse of the two who took no Glonoin to have been reduced 10 and 14 beats respectively; while the pulse of the other four who took Glonoin after running was reduced 40, 56, 56, and 14 beats respectively. So far the result agrees with that obtained by Dr. Hering. But the experiment shows also, certain undulations of the pulse. This was counted again ten or fifteen minutes after running.

No. 1 , who took no Glonoin, shows the pulse to have risen to 104 beats, after having previously sunk to 100.

No. 2 , without Glonoin, shows a steady decline from 125 to 88.

No. 3 , with Glonoin, shows a steady decline from 140 to 88. in five and ten minutes.

No. 4 , with Glonoin, shows a decline from 144 to 88 in five and ten minutes, and then a rise to 96 in fifteen minutes.

No. 5 was still more remarkable in this respect, showing a rapid diminution of pulse, from 176 to 120 in five and to 104 in ten minutes, and then a rise up to 116 in ten minutes. Prover

No. 6 showed a gradual decline. We have then a falling and rising of pulse, after severe exercise, without Glonoin, but the falling and rising is much more marked in two out of four provers who took Glonoin . The next table exhibits the effects of Glonoin on the pulse of eight provers, without preceding exercise.

Table II.

Table II.

Eight provers, five women and three men after ascertaining their normal pulse during rest, took 1 or 2 drops of Glonoin, and then counted the pulse every five minutes; the result was remarkable. The pulse of

No. 1 sank from 88 to 86, and then to 84, as also observed by Dr. Hering.

Nos. 2, 3, and 4 showed a rise after five minutes.

No. 5 showed first a falling in five minutes, then a rise after ten minutes.

No. 6 showed a rapid fall after two minutes, a rise in five, and a fall again in ten minutes.

No. 7 , having taken 2 drops, showed a decided fall in five minutes, and a rise in ten minutes.

No. 8 , like No. 1 , after two drops, showed a decline both in five and ten minutes. Aside from the probable homœopathic effect, we see in Table I that in two out of four instances (Nos. 4 and 5) there is a depression preceding a rise in the pulse, under the effect of Glonoin given during excitement by running. And Table II shows four out of eight provers to have experienced a gradual increase of the pulse, and four others a very marked decline immediately after the medicine.

This shows clearly in both tables that the primary action of Glonoin may be depression as well as elevation of the pulse. And we would be justified in drawing the inference that all other symptoms are liable to exhibit such a fluctuation, illustrating how in one or in different individuals the same drug may produce opposite effects, which are not necessarily primary or secondary.

Table III.

Table III is introduced to show that the pulse, having subsided after exercise, and having been excited again soon afterwards by a second effort, will be reduced by Glonoin. This was the case with three provers out of five. In Nos. 1, 3, and 6 the pulse was reduced lower in eight minutes after Glonoin than it was without it. This most probably finds its explanation in Table II, showing that the primary effect may be both diminished and increased action of the pulse, according to the individuality of the prover. It will therefore not always act homœopathically. Supposing, for instance, the prover to be one whose pulse is primarily depressed by Glonoin, it is then possible that the prover's pulse, when increased by running, would not be met by Glonoin homœopathically, but antipathically; for it may be found higher eight minutes after glonoin was taken during arterial excitement, than it was eight minutes after such excitement without the Glonoin . If homœopathic, it should have reduced the pulse more quickly than it would have subsided of its own accord. The instance is illustrated by Nos. 2 and 4 of Table III. It is to be hoped that the subject will be established by further experiments.

Table IV.

Table IV shows very similar results, illustrated by a larger number of counts. The columns of Series I show a steady decline of the pulse after running without Glonoin; while the columns of Series II show a decidedly irregular falling and rising of the pulse, which first diminishes, then increased and finally diminishes again. This was the case with provers 1, 2, and 5.

No. 1 had after excitement and Glonoin a diminution of pulse, till in eight minutes it rose from 102 to 108, then fell off again in ten minutes.

No. 2 , after a decided fall of pulse to 88 in three minutes, had an increase to 100 in four minutes, then a gradual decline. And

No. 5 , after having his pulse diminished to 92 in four minutes, had an increase to 96 in five minutes, and 104 in six and eight minutes, before falling to 100.

It Will be observed that prover No. 2 , whose pulse was primarily depressed in Table II, showed considerable fluctuation in Table IV; he is the only prover who appears in both tables. So far we are able to conclude that the conditions of a prover may vary at different times, showing different results from the same experiment. Furthermore, that Glonoin may raise the pulse at once in some provers, and that it may primarily diminish it in others before elevating, it during the quiescent condition of provers (Table II), and that it will affect it in a similar manner when the pulse has been excited by exercise (Table IV).

Though in a fair number of cases Glonoin will diminish the pulse quicker after its excitement by exercise than it would diminish without Glonoin, we also learn by Table IV that such homœopathic diminution does not always occur, but that the pulse may sink even more slowly under Glonoin than without it, as also shown by provers 2 and 4 in Table III.

Another purely physiological effect is also apparent, when provers excite the pulse by running a second time in ten or fifteen minutes. It will then be slower to sink under Glonoin than if only one effort to excite the pulse had been made, as in Tables I and III.

The dose is also a matter of importance. In the above experiments drop doses of the tincture (1.80) were used, and it was observed several times that increase of dose caused differences of results; thus in Table II provers 7 and 8 had 2-drop doses, followed by rapid primary depression; these were men. Two women (Nos. 1 and 5), taking only 1 drop, experienced from it the same effect as the men did from 2 drops.

Experiments are yet wanting to determine if higher attenuations will diminish the pulse quicker and with more certainty after running than the drop doses of tincture used by the provers above named, and which failed in Table IV to produce a constant decline, but tended rather to elevate the pulse.

As for Glonoin as a substance, it is one of those whose active qualities are not latent or difficult to develop. Like its new relative, Nitrite of amyl, it acts more quickly upon the organism than most other substances. It is therefore well adapted to proving, and to illustrate to novices the effects of drugs upon the body, 138.

Glonoine