Colchicum autumnale, Linn.

Natural Order , Liliaceæ.

Common name (German), Zeitlose.

Preparation , Tincture of bulb dug in spring (Stapf's provings). [According to analyses the bulbs are most active in the fall just after flowering, Schroff, Œst. Zeit. f. p. Heilk., 1856. T. F. A.]

Authorities. ( 1 to 46 , from Reil's treatise and collection, Hom. Vjschfts., 8, 113).

1 , Stoerck held the fresh root against the tongue for two minutes; 2 , same, took 3 grains of root with wine; 3 , same, took 1 grain of fresh root in bread; 4 , Lewins, Edinb. Med. Journ., 1837, a student took tincture, 20 to 60 drops; 5 , same, a student, 30 to 70 drops of wine; 6 , another person, aged 15, took 30 to 40 drops; 7 , another person, aged 17, took 30 to 70 drops; 8 , another, aged 12, took 30 drops of wine, morning and evening; 9 , another, aged 10, took 15 to 25 drops; 10 , Boecker, Beiträge, took 15 to 45 drops; 11 , other provers took 20 to 45 drops; 12 , Schroff, general summary of provings; 13 , Sonnenberg, provings with tincture, from Boecker's Beiträge; 14 , Krahmer, results of five observations (proving of tincture), Boecker's Beiträge; 15 , Bennewitz, a man, aged 60, effect of 50 drops within an hour, in one subject to gout; 16 , a man, aged 40, suffering from chronic rheumatism, took half an ounce of wine; 17 , Andreæ, 1834, a man, aged 30, took tincture of seeds; 18 , Newbrandt, a man, aged 52, took 6 ounces of an infusion of seeds; 19 , Santlus, poisoning of child of 4 years by seeds; 20 , Shilling, a boy, aged 6, ate portions of the plant; 21 , a man, aged 56, took 1 1/2 ounces of wine, Edin. Med. and S. J., 14; 22 , Boecker, effects on urine; 23 , Krahmer, Heller's Archiv., 1847; 24 , experiments by Chelius; 25 , Dr. Lindemann, seven provings with 3d to 15th dils.; 26 , same man, second series of provings, 3d dil.; 27 , same, provings with 2 to 10 drops of tincture; 28 , W. S., proving with 3d and 15th dils.; 29 , same, took tincture; 30 , C. Sch., a girl, aged 30, took 15th dil.; 31 , same, took tincture; 32 , G. Schladt, proving with 3d and 16th dils.; 33 , same, proving with tincture, 2 to 10 drops; 34 , Dr. Link, took tincture, 4 to 20 drops; 35 , same; 36 , Louisa Link, aged 35, took 5 drops of tincture; 37 , Dr. Schlosser, aged 30, provings with tincture; 38 , same, took 3d and 15th dils.; 39 , Dr. Keil, provings with tincture; 40 , Dr. Rückert, aged 59, proving with 1/10th; 41 , E. R., girl, aged 20 (suffering from chronic inflammation of conjunctiva), took the 1/10th; 42 , Dr. Zeichmann, aged 36, took 15th dil.; 43 , same, took tincture; 44 , Dr. Burkner, took tincture; 45 , Dr. Fegerl, took the dilutions; 46 , Dr. Bohler, took 3d dil.; 47 , Dr. Weber, Deutsch St. Arzk., 1864, a man took an infusion of seeds; 48 , another man took the same; 49 , a young man took the same; 50 , a girl, aged 24, took the same; 51 , Bethmann, Stapf's provings, Archiv. f. Hom., 6, 147; 52 , v. Gersdorf, ibid.; 53 , Hahnemann, ibid.; 54 , Schweikert, ibid.; 55 , Stapf, ibid.; 56 , Marges, Journ. d. Med., 23, from Stapf; 57 , Ehrmann, Diss. de Colch., ibid.; 58 , Boerhaave, ibid.; 59 , Peyer, Peonis et Pythag. exercit., 50, ibid.; 60 , Hopf, Comment. Zom., 6 (1800), ibid.; 61 , Actuarius, Method. Med., lib. 3, ibid.; 62 , Nationalzeit, 1810, ibid.; 63 , De Berge, Journ. d. Med., 22, ibid.; 64 , Collin, Ann. Med., P. II, ibid.; 65 , effects of bruising seeds in preparing tincture, from Unsin's collection of cases, A. H. Z., 52, 42; 66 , Dierbach, two children poisoned by seeds, from ibid.; 67 , Ferreday, Lond. Med. and Phys. J., 1832, a man took two ounces of seeds, from ibid.; 68 , Amer. Med. Lib. and Intell., 1839, some soldiers drank some wine of Colchicum, ibid.; 69 , Hufeland's Journ., 1841, effects of a drachm of wine taken daily, ibid.; 70 , Siebert, Trans. of Nat. Hist. Soc. of Brunswick, 1842, general effects, ibid.; 71 , Maclagan, Mon. Journ., 1851, a young man, aged 26, took 20 drops of tincture, ibid.; 72 , same, another man, aged 25, took 10 drops of tincture, afterwards 24 and 30 drops, ibid.; 73 , same, a healthy girl took 5 drops of tincture, ibid.; 74 , the same, B. proved repeated doses of 1 to 5 drops, ibid.; 75 , Ollivier, Archiv. Gén. de Méd., 1836, a girl, 20 years old, took 4 to 5 ounces of tincture; 76 , Forget, Hygeia, 15, 87, a man, aged 60, took tincture in doses of 1 drachm to 1/2 ounce daily, for articular rheumatism; 77 , Roux, l'Union Méd., 1855, five persons, after operations, were given 60 drachms of tincture by mistake for China; 78 , Dr. Freree, Journ. Hebdom., 1835, a girl, 25 years old, took 5 ounces; 79 , Chevallier, J. de Chim. Méd., poisoning; 80 , Goullon, poisoning (by tincture taken for schnapps); 81 , Sir Ev. Home, experiment on self with the wine (Phil. Trans., 1816 and 1817); 82 , Dayton, poisoning by about 2 ounces of wine, Am. Med. Times., 5, 337; 83 , Henderson, poisoning of a woman by nearly 1 ounce of tincture, Lond. Med. Gaz., 24, 763; 84 , Warncke, a boy, aged 14, drank a wine glass and a half of wine of Colch., Hosp. Tidende, 1863; 85 , Balluf, Diss. de Colch., 1845, poisoning of a boy, aged 2 1/2, by the seeds.

MIND

Emotional.
Delirium (second evening), 21.
Delirium at night, 76.
Carphologia, 20.
Lively mood (alternate action), (third day), 37.
Especially lively mood (second day), 27.
Sad mood (third day), 37.
Anxiety, 17, 65, 77.
Anxiety, causing sighing, 27.
Irritable and peevish (second day), 32. [10.]
Very ill-humored; irritable mood (fourth day), 44.
Out of humor; apprehensive of impending evil, 33.
Fretful mood, 11.
Very fretful, 10.
Great peevishness (second day), 32.
Morose, ill-humored, nothing is right, 51.
External impressions, for example, bright light, strong odors, contact, the misdeeds of others, make him quite beside himself, 51.*
Intellectual.
Great flow of thoughts at night, which disturb sleep (second night), 25.
Intellectual faculties very much weakened, 15.
The consciousness of logical connection was entirely destroyed, and his perceptive faculties were impaired by the slightest circumstances which interrupted the sequence of ideas, 15. [20.]
Was unable to write connectedly, 15.
Inability to fix the thoughts, wherewith the forehead seems tense, 27.
Weakness of memory; he forgets the words which he is about to speak, and can with difficulty collect his thoughts and continue to speak (thirteenth and fifteenth days), 51.
Very forgetful and absentminded, 51.
Loss of consciousness, 20.
Loss of consciousness and of pulse (second day), 20.
Became immediately stupefied, when laid in bed; could, however, be easily aroused and made conscious, 85.

HEAD

Confusion and Vertigo.
Confusion of the head, 12 ; (second morning), 30 ; (second day), 32, 34, 77.
Confusion of the head, posteriorly and superiorly, 34.
Confusion of the head, with slight vertigo, 71. [30.]
Confusion of the head, with headache, 55.
Confusion in the forehead (first day), 25.
Confusion of the forehead, worse on walking in the wind, better in the room, 27.
Some confusion of the forehead (after one hour), 27 ; (third day), 26.
Somewhat confused in the head, in the morning, 39.
Vertigo, even to falling, while sitting after walking (soon), 32.
Slight vertigo, on rising (second day), 32.
Momentary slight vertigo, 33.
Sensation of vertigo and dizziness in the head (soon after), 36.
Dizziness of the head, with confusion in the middle of the forehead, 27.
General Head. [40.]
Perceptible pulsation in the head (after one hour), 39.
Head falls backwards, 20.
Congestion of the head, without headache, 39.
The head seems thick, 27.
Great pain in the head, 3.
Headache, 7 ; (soon), 20, 66, 84.*
Headache deep in the head, extending across through the head between the ears and somewhat posteriorly, not very violent, 35.
Headache, coming on in the evening, very violent, and lasting through the night (fifth day), 36.
Transient headache (fourth day), 10.
Transient headache in the evening, 13. [50.]
Feeling as if something tightly bound the head (third day), 83.
Pinching pains in different places, here and there in the head; transient, 52.
Pressive pain in the whole head, on going into a room after walking in the open air, disappearing after some sleep (fourth day), 40.
Pressive, finely burrowing headache, more on the right side and in the vertex (fourth day), 44.
Feeling as though the previous headache would return, especially on shaking the head, after rising in the morning; after washing this became a pressive headache and continued the whole day, becoming worse towards evening, seated in the outer posterior portion of the head, 34.
Frequent slight stitches in the brain, 39.
Transient stitches in the brain, especially in the forepart, beneath the coronal suture (after one hour), 39.
Tearing in the head, especially in the frontal region, 73.
Forehead.
Very severe pain in the whole of the forehead, especially above the eyebrows, and extending into the dorsum of the nose (third day), 71.
A very violent pain in a small spot in the right side of the forehead, on waking in the morning, 34. [60.]
Neuralgic pain in the right frontal eminence, pressive corresponding to a dull pain in the right occipital protuberance, relieved by pressure and cold, 38.
Headache above the left eye immediately after eating, better in the open air, but continues and is very troublesome in the room, 41.
Fine headache in the middle of the forehead, together with a peculiar hyperæsthesia of the cranial nerves, 15.
Slight dull headache in the forehead near the coronal suture (after one hour), 39.
Boring frontal headache above the right eye (second morning), 32.
Boring frontal headache, especially over the left eye (second proving, second day), 32.
Tearing tension in a spot on the left half of the forehead, as if an abscess would form, 52.
Transient drawing headache just above the eyes, pinching, 52.
Pressure in the frontal region, as if everything would press outward, 73.
Pressive sensation in the forehead and eyes (second day), 25. [70.]
Pressive pain in the frontal region, 73.
Pressive pain in the right, and afterwards in the left frontal region, 74.
Pressive pain in the upper part of the forehead, following the pain in the occiput; relieved by warmth and rest in bed, 34.
Pressive frontal headache above the right eye (third day), 33.
Oppressive frontal headache above the eyes, in the afternoon (second day), 32.
Transient stitches in the forehead above the eyes, in the shoulders, elbows, and wrists (first day), 32.
Transient stitches in the forehead above the right eye (first day), 32.
Temples.
Headache in the right temple in the evening, relieved when quiet in bed, 34.
Painful drawing in the left temporal region, 45.
Sticking pressure in the right temple, mostly in the evening, 37. [80.]
Tearing in the right temple, 52 ; (third day), 33.
Jerking tearings in the temples, 71.
Vertex.
Pain in the top of the skull, as if something were boring into the head; this painful spot moves along the sagittal suture, 71.
Slight pressive headache in the vertex (first day), 44.
Oppression in the vertex, 37.
Parietals.
Drawing in the upper part of the left side of the head, extending down into the nose, 52.
Pressive headache in the right parietal eminence (fourth day), 37.
Pressive headache in a small spot on the upper part of the right side of the head, transient, 52.
Tearing in the left half of the head, extending to the vertex, 52.
Sharp, very painful drawing tearing in the left half of the head, which mostly commences in the eyeball of that side, and extends towards the occiput, lasting several days, 51. [90.]
Crawling boring-tearing in a small spot on the upper part of the right side of the head; the same pain appears afterwards in the left side, 52.
Occiput.
The headache extended from the forehead towards the occiput, towards evening, 39.
Dull drawing pain, extending from the nape of the neck across the occiput to the ears, 71.
A pressure, not very violent but very troublesome, deep in the cerebellum, caused by the slightest literary occupation, 51.
Severe pressure in the right side of the occiput (after half an hour), 54.
Oppressive heaviness in the occiput, especially on motion, or on bending a little forward, 51.
Tearing in a small spot on the left side of the occiput, 52.
Pressive-tearing pain in a small spot on the right side of the occiput, 52.
External Head.
The hair falls out freely, 51.
Sensation as though the scalp were drawn from behind forward to the top of the skull, 71. [100.]
Fine tearings in the scalp, 51.
Sleepless nearly the whole night on account of sticking jerks, sometimes only in the skin sometimes deep in the soft parts of the head and face, 51.
Crawling in the head beneath the forehead, 55.

EYE

Objective.
Eyes wide open, staring, like one intoxicated, 85.
Eyes surrounded by dark rings, (84); (after eighteen hours), 17.
Eyes surrounded by deep dark rings, 65.
Convulsive rolling of the eyes (after four weeks), 20.
Distortion of the eyes, 85.
Subjective.
Dryness of the eyes, 74.
Heaviness in the eyes, as though he had not slept enough, with injected vessels, 39. [110.]
Aching in the eyes, 52.
Pressive pain in the right eye, 52.
Short, violent sharp tearing in and around the right eye, 52.
Biting in the right eye, especially in the external canthus, with some lachrymation and feeling as if the lids were agglutinated, 52.
Brow.
Pain in the bone over the left eye, on every motion; in the afternoon and evening, it increased to such a severe ache above the left eye, that every slight noise seemed intolerable; the pains remained constant at the same place (soon after taking), next day, the headache returned to the same place; aggravated by every motion of the head; on the third day, the same pain, but instead of over the left eye, it was in the right side of the occiput; aggravated by bending the head backward, or raising the eyes; next day, very severe headache, commencing at 6 P.M., above the left eye, and extending over the whole left side of the head, disappearing after supper (fourth day); on the next day, she awoke without headache, returned in a short time in the left side of the occiput, and extended to the left eye, and even into the face, 36.
Constrictive sensation above the eyes (second day), 44.
Slight momentary pressure in the eyebrows, 27.
Deeply piercing sticking in the upper part of the left eyebrow, with a feeling as though it were drawn upward, 73.
Fine stitches above the right eye (second day), 33.
Lid.
Ulceration of the Meibomian glands of the left lower lid, with swelling of the lid and great irritability of the nerves generally, 52. [120.]
Eyelids in constant motion (second day), 20.
Twitching in the right upper lid, 52.
Slow but visible drawing (similar to twitching), in the left lower lid, towards the inner canthus, 52.
Burning and redness of the margins of the lids, as in blepharitis (fourth day), 37.
Lachrymal Apparatus.
Lachrymation in the open air, so that I could scarcely see for several days, 34.
Ball.
Corner of the left eye (which was usually perfectly clear like the right) became affected by a small white clearly defined macula, with some redness of the sclerotic (fourth day); [This symptom occurred after antidotes of Tartar emetic, Ipecac, Cinnamon, etc. -T. F. A.] on the next day the ball was enlarged, the macula could be noticed only on the most careful examination; the cornea was somewhat dim, and a small quantity of purulent matter was found at the bottom of the anterior chamber; the lens and lens capsule seemed obscured; a complete capsular cataract seemed to have developed in a few hours; it was treated with Acetate of lead locally, with Tartar emetic ointment on the neck, and leeches on the left temple after some days, the inflammatory symptoms subsided; the lens was obscured and had a greenish reflex; afterwards a membranous flake was seen in the anterior chamber attached by its upper extremity to the lower margin of the pupil, with the lower extremity directed towards the lachrymal canal; it was about two lines long and half a line broad; the lens was distinctly seen to be obscured, the iris turbid, the pupil extremely sensitive to light; after two weeks the greenish turbidity of the lens seemed to lie farther back, 20.
The cornea became very convex and pointed; the lens, which was opaque, seemed to be enlarged, and pressed forward against the iris (ninth day). On the twelfth day, the eye had improved; there was still some dimness in the posterior chamber, due to the lens, which had a greenish reflex; around the margin of the pupil, behind the iris, could be noticed a yellowish membranous exudation, which afterwards became firmly adherent in the posterior chamber; the iris was brown and dim; the pupils, however, extremely sensitive to the light; this membranous exudation afterwards sank to the bottom of the anterior chamber, 20.
Sclerotic of left eye became slightly red, cornea covered with sharply defined white spots; some purulent fluid collected in the anterior chamber, and a capsular cataract seemed to form in the posterior chamber (fifth and sixth days), 20.
The lens hand the color of verdigris (after two weeks), 20.
Drawing digging deep in the eyeballs, 51. [130.]
Pressive pain in the left eyeball, 34.
Feeling in the right eye as if the ball were compressed lasting several seconds, and frequently returning (third day), 71.
Pupil.
Uneasiness of the pupils (after half an hours), 44.
Pupils dilated, 20.
Pupils somewhat dilated, 85.
Pupils slightly dilated, 19.
Pupils much dilated (second day), 20.
Pupils contracted, 65, 68 ; (after eighteen hours), 17.
The right pupil moderately dilated, the left extremely contracted (after six weeks), 20.
Vision.
Visual power was unusually acute, 15. [140.]
Eyes dim (second day), 32.
On attempting to stand, it became black before the eyes, 67.

EAR

External.
Pain behind the left ear, as if the gland were swollen, 41.
Tearing behind the right ear, in the region of the articulation of the lower jaw; the place was painful to touch for some time, 52.
Internal.
The ears feel stopped, with roaring in them, if he takes a few steps about the room, 51.
Right ear feels stopped (fourth day), 26.
Earache, then sticking as with needles in the ears, deep in, 52.
Digging in the right ear, soon, 33.
Pinching pains in the ears, 51.
Twinging sticking in the left ear, 52. [150.]
Stitches in the left ear, 41.
Transient stitches in the left ear (after seven hours), 39.
Tearing in the right meatus auditorius, 51.
Itching deep in the ears; inclination to bore into the ears, which were internally very dry; boring does not relieve the sensation, and does not even reach the itching painful spot, 35.
Hearing.
Difficult hearing, 20.
Ringing in the right ear, 33.
Roaring in the ears, 31.
Great roaring in the right ear, 73.

NOSE

Objective.
Sneezing (soon after taking), 52.
Catarrh in the nose and fauces (fourth day), 37. [160.]
Violent coryza, 35.
Obstinate coryza, which is never thin, and with which much tough mucus is discharged from the nose, 52.
Decided fluent coryza (fifth day), 37.
Transient fluent coryza (second to fourth days), 25.
Epistaxis, in the evening, 51, 73.
Subjective.
Nostrils dry and blackish, 20.
Slight irritation to sneeze, 71.
Sensation in the mucous membrane of the nose as of commencing coryza, 71.
Sensation of warmth and crawling within the nose, as in nosebleed (after a quarter and half an hour), 54.
Pinching sensation in the upper part of the nose, 52. [170.]
Pressure and tearing in the nostrils, 71.
Pressure in the nasal bones, 71.
Pressure in the bones of the nose and face, 71.
Sensation in the nasal bones, as from the pressure of a weight (after one hour and a half), 54.
Sore pain in the septum of the nose, in the right nostril; especially violent on touching the spot, and on moving the nose, 52.
Crawling in the nose, 52.
Crawling in the nose, with sneezing, 52.
Crawling in the tip of the nose, 54.
Smell.
Smell became very acute, 11.
Smell so acute that the laboratory work was almost unendurable, 10. [180.]
The sense of smell is so morbidly acute, that the odor substances to which he was usually quite indifferent, as, for example, broth, nauseates him, 51.
The odor of a freshly beaten egg makes him almost faint (fourth day), 51.
Smell as of smoked ham, 34.

FACE

Objective.
Expression very suffering, 80.
Complaining, sad expression, 51.
Expression of anxiety, 13.
Face expresses great anxiety, 67.
Paleness of the face, 48, 50.
Very great paleness, 78.
Face pale (second day), 32. [190.]
Face pale and sunken, 16, 65 ; (after eighteen hours), 17.
Face very pale, 80, 85.
Face bluish-white, 84.
Face sunken, 68.
Face sunken, Hippocratic, 19.
Features drawn, 76.
The features are completely changed, and look as if he had been long sick (after five hours), 51.
Subjective.
Pain in the face, in a small spot on the right side, near the temple (fourth day), 44.
Pain in the face, or twinges in the ears, near the right articulation of the jaw (second day), 44.
A very unpleasant sensation in the bones of the face, as if they were widely drawn asunder; with some drawing jerkings in them, 51. [200.]
Jerking-drawing pain in the muscles of the face, deep into the bones, 51.
Tearing and tension in the left side of the face, extending to the ear and head, 53.
Cheeks.
Cheeks red and hot, 27.
Cheeks, lips, and right eyelids purple-red, 13.
Cheeks, lips, and eyelids purple, 67.
Cheeks and chin alternately pale and red (after six weeks), 20.
Sensation in both cheeks as if they would be drawn asunder, 71.
Slight drawing in the upper jaw, on the right side, extending to the margin of the orbit, transient, and alternating with irritation in the throat (I am not subject to toothache), (after half an hour), 46.
Stitches in the left cheek, 73.
Tearing in the right upper and lower jaws, with a sensation as if the teeth were too long, 54. [210.]
Dull pain in the left cheek, as from a bruise or blow, 74.
Lips.
The lips became very pale and tender; the slightest motion of the mouth cracked the skin of the lower lip, 41.
Lips only slightly red, 80.
Lips bluish, 85.
Lips and tongue bluish and dry, 84.
Blue lips and nails, 77.
Lips violet, 78.
Hydroa on the upper lip, 25.
Lips cracked, 56.
Sharp cutting tearing in the vermilion border of the upper lip, left side, 52.
Lower Jaw. [220.]
Severe tension in the articulation of the lower jaw, so that he was obliged to lay aside the cigar, and felt relieved when he had finished it, 34.
Pinching pain in the right articulation of the jaw, 52.
Sticking pressure beneath the left lower jaw (after four hours), 39.
Stitches in the left side of the lower jaw, sudden and transient, 39.
The masseter muscles seem increased in breadth, allowing him to open his mouth only a little, and with pain, 51.

MOUTH

Teeth.
Grinding of the teeth (after three days), 20.
Sensation of bluntness of the teeth, with drawing pain extending from the tips of the teeth of the upper jaw into the jaw-bone, 71.
The teeth seem too long, 71.
Toothache; the teeth seem too long, 73.
Painful grumbling in the upper back teeth, 52. [230.]
(Decayed teeth became painful when chewing), (second day), 32.
Drawing and cold sensation in the incisors of the lower jaw, 74.
Drawing pain in the teeth, caused by taking anything cold immediately after something warm (after two hours and a half), 54.
Pressive toothache in the left lower back teeth, 52.
Stitches in the teeth of the right side, 41.
Tearing in the roots of the left lower teeth, 52.
Toothache, making the teeth sore, 52.
The teeth are so sensitive that he is unable to bite upon them, 51.
Gums.
Follicular inflammation of the gum, about the right incisors, 38.
Tearing in the right lower gum, 35. [240.]
Tearing in the gum of the left lower front teeth, 52.
Tearing in the upper part of the gum, in the upper part of the right side of the mouth, above a hollow tooth, 52.
Tongue.
Tongue very white, 85.*
Tongue pale-blue, and cold, 72.
Tongue very yellow, 65.
Tongue, red, covered with mucus, 49.
Tongue bright-red, coated only at the root, 19.
Tongue coated in the morning, 11.
Tongue somewhat coated in the morning, 10.
Tongue coated white (second day), 32. [250.]
Tongue thickly coated yellow (after eighteen hours), 17.
Tongue covered with thick brown fur (after eight days), 20.
Heaviness of the tongue; it was difficult to find the right word, and, when found, to articulate it, 15.
The tongue became at first heavy, then stiff, and lastly insensible, so that it was almost without sensation for six hours, after which it gradually recovered, 1.
Velvety sensation on the tongue, 39.
Burning in the tongue, 57.
Prickling burning on the margin of the tongue (after one hour and three-quarters), 37.
Sensation of burning, and fine sticking on the tongue, 56.
Fulness of the tongue, 74.
Sensation as though the tongue were enlarged, 74. [260.]
On moving the tongue, and in swallowing, she experienced sharp pain about the root of the tongue (third day), 83.
Tearing in the back part of the left side of the tongue, 52.
Some transient stitches in the middle of the tongue (after nine and thirteen hours), 54.
Biting sensation on the tongue and in the throat, 46.
General Mouth.
A small follicular ulcer of the size of a pea in the commissure of the upper lip and gum, with burning pain; it continues to enlarge till after a dose of Kali bichrom. (third day), 37.
Blunted sensibility of the whole mouth, especially of the tip of the tongue; immediately, 71.
Dryness of the mouth (first night), 32.
Sensation of warmth and dryness in the mouth (after two hours), 39.
Heat in the mouth, rather more thirst than usual, 55.
Burning in the mouth and stomach, 70. [270.]
Burning in the mouth and whole of the pharynx, 11.
Excessive burning in the mouth, 17, 65.
Scraping, with pasty taste and great hunger, 39.
Constant scraping-crawling sensation in the posterior portion of the palate, as in coryza, 52.
An agreeable prickling sensation in the mouth (as after the carbonic acid of champagne), with increased secretion of saliva, 37.
Saliva.
Increased secretion of saliva, 74 ; (after a quarter of an hour), 54.
Increased secretion of agreeable-tasting saliva, 38.
Secretion of saliva greatly increased immediately, 71.
Profuse salivation, the whole day, 54.
Very profuse salivation (eighth day), 51. [280.]
Expectoration of much watery saliva, 51.
Great collection of watery saliva, with nausea, fulness, and discomfort in the abdomen (after four hours), 51.
Constant accumulation of watery saliva for several days, with dryness of the throat, 51.
Salty saliva, having a peculiar piquant taste (after one hour and a quarter), 37.
Collection of water in the mouth (after a quarter of an hour), 54.
Some greenish mucus is involuntarily thrown out of the mouth, while sneezing, 52.
Taste.
Taste pasty (second morning), 32.
Bitter taste in the mouth, 74.
Bitter flat taste in the mouth (second day), 44.
Taste bitter and flat, 27. [290.]
Transient bitter taste (soon after), 27.
Even strongly tasting food causes a sensation as if he were chewing a piece of old linen, 51.

THROAT

Objective.
Perceptible pulsation in the carotids (after nine hours), 39.
Inflammation of the whole throat, 51.
Much mucus collects in the throat; it has a greenish look when expectorated, 52.
Frequent hawking of scanty mucus, 39.
Subjective.
Dryness of the throat (after two hours), 38, 48, 50.
Dryness and scraping in the throat, 34.
Some dryness in the throat, 27.
Great dryness in the throat, as if painful on swallowing, like a commencing catarrh, 35. [300.]
Scraping dryness in the throat, 34.
Sensation of dryness in the throat; the uvula, as well as the arches of the palate, is slightly red (first day), 26.
Scraping dry sensation in the throat, with tickling cough (after half an hour), 46.
Constriction of the throat, 58.
Pinching in the posterior portion of the throat, as in commencing angina; with great dryness in the throat, and somewhat impeded swallowing (second day), 44.
Tearing far back in the throat, more on the left side, 52.
Rawness in the throat, with a hoarse voice, in the morning, 52.
Constant crawling in the thorax, with loosening of thin mucus, so that it must be frequently expectorated, 52.
Severe crawling in the throat, which provokes a hacking cough and hawking of mucus, 52.
Biting crawling in the back of the throat, 52.
Uvula. [310.]
Uvula painful and red, 27.
Burning in the uvula, soon followed by profuse pale urine (after a few minutes), 2.
Pharynx and Œsophagus.
Slight constriction of the pharynx, 71.
Burning heat in the pharynx and along the œsophagus, 77.
Sensation at the commencement of the œsophagus, on drinking, as if there were a large round swelling there, 51.
Swallowing.
Difficult swallowing, 17.
Swallowing difficult, 65.
Swallowing difficult, with pain along the œsophagus (after eighteen hours), 17.

STOMACH

Appetite.
Increased appetite (after four hours), 27, 45.
Appetite increased, at noon (first day), 33. [320.]
Appetite for dinner increased (second day), 32.
Great appetite, 31.
Great appetite, in the evening (first day), 25.
Appetite was very voracious during the whole proving, 26.
Enormous appetite (third day), 25.
Hunger in the afternoon (first and second days), 25.
Sensation of hunger, soon, 28.
Sensation of gnawing hunger; almost a throbbing in the stomach (after a quarter of an hour), 44.
Appetite diminished, 11.
Loss of appetite, 7, 51 ; (third day), 5. [330.]
Entire loss of appetite, 3.
No appetite for breakfast, 10.
He has appetite for different things, but as soon as he sees them, or still more, smells them, he shudders from nausea and is unable to eat anything, 51.*
Thirst.
Thirst (soon), 20.
Thirst increased, 10, 11.
Much thirst, 58.
Great thirst, 84, 85 ; (after four hours), 82.*
Great thirst, in the afternoon, 74.
Excessive thirst, 3, 79.
Extreme thirst, with the most violent pain in the stomach and bowels, 21. [340.]
Unquenchable thirst, 17, 19, 65 ; (after fifteen hours), 67 , etc.
Tormenting thirst, 69.
Burning thirst, 78.
Desire for cold drinks, 17.
Eructation and Hiccough.
Eructations, 45, 71 ; (after five minutes), 73.
Eructations and profuse vomiting of yellow fluid, 13.
Eructations, with burning in the stomach (after half an hours), 74.*
Frequent eructations (second day), 30, 69.
Frequent eructations and yawning (nothing unusual), 39.
Constant eructations and retching, without vomiting, 13. [350.]
Empty eructations (third day), 33.
Empty, tasteless eructations, 39.
Frequent empty eructations, soon, 32.
Many empty eructations, in the forenoon, 52.
Constant eructations of air, 51.
Eructations of water, 29.
Hiccough, 59.
Hiccough, for fours at a time, 51.
Heartburn.
Slight heartburn (after one hour), 1.
Nausea and Vomiting.
Nausea, 45, 66 ; (immediately), 55. [360.]
Nausea in the throat, caused by pressure from below, 34.
Nausea after dinner of which he could eat only a little, 11.
Nausea at times, during dinner, 54.
Nausea, on assuming an erect position, 51.
Nausea, and inclination to vomit (second day), 32.
Nausea, with inclination to vomit if he swallows the saliva, 51.
Nausea, with copious and easy vomiting, immediately followed by appetite, 6.
Nausea, and vomiting of bile, 7.
Nausea, and vomiting of tenacious bile, 9. [370.]
Nausea, increasing after every dose until he vomited three times; after which he ate a little, but it was immediately vomited, 6.
Nausea, becoming very violent; continuing until the next day, when he vomited, in the morning, more than a quart of a thick whitish substance; and again vomiting, at 11 A.M., of much tenacious greenish matter; soon repeated; also, at 3 P.M., vomiting of some brandy and water which he had taken; and again, vomiting at 4 P.M.; the nausea still continued on the third day, during which it gradually abated, 5.
Slight nausea, after eating, 10.
Great nausea, with trembling of the abdomen, and painful contractions and gripings, in the morning, on waking (third day), 71.
He feels so very much nauseated and so qualmish, with constant accumulation of saliva and dryness in the throat, that he turns hither and thither discouraged, with great distraction of mind and loss of physical power (after five hours), 51.
Standing up increases the nausea and causes vomiting of bitter fluid, 71.
The nausea is relieved for a short time after every attack of vomiting, 51.
Qualmishness, 39.
Retching and eructations (after one hour), 71.
Violent retching; after retching a long time, vomiting of a large mass of yellowish mucus, bitter as gall, and leaving a bilious bitter taste in the throat, 51. [380.]
Inclination to vomit, 45.
Vomiting, 59, 69.
Vomiting frequent, but scanty, 7.
Vomiting of a whitish-gray fluid, 80.
Vomiting of green fluid, 20.
Vomiting of much yellowish-green water, 65.
Thin and slimy vomiting, 79.
Vomiting of food and pale greenish mucus, 19.
Vomiting of undigested food and yellow liquid, followed by diarrhœa, 84.
Vomiting what he had taken for breakfast (after one hour), 82. [390.]
Vomiting, first of food taken the night before, followed by a great quantity of thick, yellow bile, several basinfuls (after three hours). The matter vomited became thinner and less yellow, and ultimately (after twenty hours), it was of a pale straw-color, containing a large quantity of small white shreddy particles, 83.
Vomiting, with watery diarrhœa, 85.*
Repeated vomiting, 75.
Vomiting frequent, throwing up his drinks, tinged with bile (after four hours), 82.
Frequent vomiting of a yellowish-green fluid, lasting the whole day; and so violent that he was unable to retain the slightest food or drink, 16.
Frequent vomiting of bile, with violent griping in the abdomen, followed by bitter taste in the mouth and throat, 51.
Constant vomiting, 77.
Almost incessant vomiting of colorless and inodorous fluid, 78.
Excessive vomiting and retching, 48.
Violent vomiting of a brown substance, 76. [400.]
Violent vomiting of all the food eaten three hours previously (after six hours), 51.
Violent vomiting and diarrhœa, 17, 65.
Violent vomiting (with trembling and cramps), 60.
Vomiting, very violent, at first of greenish water, afterwards of the contents of the stomach, 66.
He was obliged to bend himself up and lie quite still the whole day, without the slightest movement, else he was seized with the most violent vomiting, 51.*
Frightful vomiting, 49.
Frightful vomiting, at first of food mingled with a brown, bitter powder, at last of water, partly bitter, partly flat-tasting mucus, 47.
He was only able to lie upon the right side; frightful vomiting was renewed on every motion or change of position, 51.
Stomach.
Rumbling and moving in the stomach, 37.
Gastritis, 19. [410.]
Desire to hiccough, 3.
Weakness and oppression of the pit of the stomach, 84.
Uneasiness at stomach (after one hour), 82.
An unpleasant sensation in the stomach, extending backwards to the spinal column (after one hour), 71.
Sensation of emptiness and faintness in the stomach, even breakfast, 72.
Sensation of warmth and fulness in the epigastric region, 27.
Sensation of increased warmth and fulness in the stomach, 71.
The stomach seems constantly icy cold, 51.*
Feeling of disordered stomach, with many eructations, tasting of undigested food (fifth day), 40.
Pain in the stomach, 45. [420.]
Pains in the stomach and abdomen, 66.
Pain in the epigastric region; although the stomach feels swollen, this is not the case; it endures no pressure, so that even light clothing is annoying (fifth day), 36.
Pain over region of stomach, with nausea and frequent vomiting; the pain gradually extended itself over the abdomen (after one hour), 82.
Great pain at stomach (after three hours), 83.
Severe pain and tenderness over region of stomach, and extending over bowels (after four hours), 82.
Violent pains in the stomach, 69.
Violent pain in the stomach, in the morning, 30.
Violent pains in the epigastrium (after ten hours), 67, 75.
Intolerable pain in the epigastrium and in the whole of the abdomen, 77.
Epigastrium painful, especially to pressure, 78. [430.]
Burning in the stomach after a quarter of an hour, continuing for an hour; at last it seemed to spread upward along the sternum, 3.
Burning and heaviness in the stomach, 61.
*Violent burning, in the epigastrium, 77.
Violent burning and pain in the stomach, 72.*
Fulness of the stomach, as though she had eaten very much, 73.
Fulness of the stomach, as if sensitive to the pressure of the clothes (fourth day), 44.
Fulness, tension, and oppression in the epigastric region, especially while walking (third day), 44.
Severe tension in the epigastric region, 3.
Constriction in the stomach (after three-quarters of an hour), 71.
Cramp in the stomach, 45. [440.]
The stomach became spasmodically contracted when touched, 18.
Pressure in the stomach, 12.
Pressure in the stomach, after a light meal (third day), 33.
Pressure and discomfort in the epigastric region (after three-quarters of an hour), 71.
Slight pressure in the stomach, 39.
Slight pressure in the stomach, extending into the left side of the abdomen (after half an hour), 39.
Pressive pain in the stomach; in the evening, while walking (second day), 44.
Oppression and violent pressure in the epigastric region (after five hours), 17.
Oppression and excessive pressure in the pit of the stomach, 65.
Slight oppression in the pit of the stomach, 52. [450.]
Violent tearing pains in the stomach when he began to vomit and purge (after one hour), 21.
Unpleasant sensation in the stomach, as if sore, 55.
Epigastric region sensitive to pressure, 48, 80.
Epigastrium extremely sensitive to pressure, 50.
Epigastric region cannot endure the slightest touch, 51.
Crawling in the stomach, 51.
Crawling in the stomach on becoming erect, amounting even to vomiting, 51.

ABDOMEN

Hypochondria.
Increased secretion of bile, 69.
The secretion of bile was constantly increased after Colchicum, as shown not only in the stools, which were always very bilious and copious, but also in the bilious vomiting, 22.
Pain, as from incarcerated flatus, immediately under the short ribs of the right side, 52. [460.]
Inability to sleep, on account of not being able to lie on the left side according to habit; it constantly seemed as though a fold, or something of that kind, pressed against me; this however, was not the case, and I found that a pain in the region of the spleen was the cause, and that it was especially noticed on external pressure, 34.
Tensive sensation transversely across the hypochondria (after four hours and a half), 39.
Slight sticking in the left hypochondrium, 39.
Tearing in the left hypochondrium, 34.
Cutting-tearing pains in the hepatic region, 34.
Transient stitches in the spleen in the evening (first day), 33.
Umbilical.
Sharp pressing-outward pain above the navel, somewhat to the left side, 52.
Violent sharp stitches in the umbilical region, 52.
Pressive colic about the umbilical region, with flatulence, before and at the commencement of the midday meal, 52.
Sticking colic here and there below the umbilical region, 52.
General Abdomen. [470.]
Abdomen distended (third day), 33.*
Abdomen distended, tense, and hard, 19.
Abdomen greatly distended, 85.
Great distension of the abdomen, 63.
Great distension of the abdomen, as if she had eaten too much , although she had not taken the slightest food; after taking a moderate amount of very light food this sensation became much more troublesome (after three hours), 55.*
The abdomen became extremely distended in a short time, 62.
Abdomen not distended but doughy, and painful on the slightest pressure (after four weeks), 20.
Abdomen sunken, 80.
Violent enteritis, 79.
Movings about in the abdomen, as though diarrhœa would ensue, 51. [480.]
Rumbling in the abdomen, soon, 33 ; (first day), 32.
Rumbling in the abdomen, as with diarrhœa (nothing unusual), 39.
Rumbling in the abdomen, as from wandering gases in the transverse colon (second day), 37.
Rumbling in the abdomen, with griping colic, 70.
Rumbling in the abdomen and urging to stool, 11.
Rumbling in the bowels, with urging to stool, 10.
Rumbling in the intestines, followed by soft stool and after half an hour by a second still softer (second day), 46.
Slight rumbling in the abdomen, soon giving place to a sensation of hunger, 39.
Passage of flatus (second day), 30.
Passage of odorless flatus (second day), 32. [490.]
Very offensive flatus in the evening, 72.*
Much forcible offensive flatus, 35.
Discomfort in the abdomen (second day), 44.
Uneasiness in the abdomen, with movings and urging to stool, 72.
An unpleasant sensation (ache) in the upper abdomen, on pressure (second day), 25.
Sensation of weakness in the abdomen, becoming hunger, 39.
Feeling as though flatulence was incarcerated in the abdomen, 39.
Pains in the abdomen (after one hour and a half), 67.
Pain in the abdomen, as from incarcerated flatus, 55.
Violent pain in the bowels, 76. [500.]
Some burning in the abdomen below the navel, with slight dragging towards the small of the back, 39.
Slight burning here and there in the abdomen, which gradually became violent, and changed to a transient but severe griping (after a few hours), 3.
Fulness in the abdomen, 39.
Fulness of the abdomen after eating, relieved after a copious, thin, pasty stool, 11.
Sensation of fulness in the abdomen (fifth day), 36.
Feeling of fulness in the abdomen after supper, 10.
Slight tension in the upper abdomen, extending to the right hypochondrium, 39.
Painful constriction of the abdomen precedes vomiting, 51.
Cramps in the muscles of the abdomen and flexors of the limbs, 68.
Very violent cutting cramplike pain in the upper abdomen, extending to the navel, in the evening, lasting half an hour, similar to a colic or premonitions of diarrhœa, 34. [510.]
Griping in the abdomen, 18, 69, 73.
Griping in the abdomen, with unsatisfactory stool (third day), 33.
Griping in the abdomen, followed by pasty stool (second day), 33.
Gripings and movings in the abdomen (after three-quarters of an hour), 18.
Slight griping, as from flatulence or diarrhœa (fourth day), 46.
Griping pains in the abdomen, 72.
Pinching pain in the abdomen near the right hip, 52.
Aching and discomfort in the whole abdomen, 51.
Constant slight drawing sensation in the abdomen, as if colic would occur, 39.
Dragging and moving in the transverse colon, 37. [520.]
Dragging sensation, extending from the abdomen to the chest, with anxiety and heat, especially of the head, lasting two hours (after one hour), 54.
Gnawing in the abdomen, 11.
Some gnawing in the abdomen, 10.
Pressure in the abdomen, 55.
Pressure in the left side of the abdomen, as from incarcerated flatus; the place is also sensitive to pressure, 39.
Pressure and discomfort in the region of the transverse colon (sixth day), 43.
Some pressure in the upper abdomen, in the morning, on waking, 52.
Sticking pressure in the left portion of the transverse colon, momentary (second day), 37.
A painful, uncomfortable sensation of pressure in the abdomen, relieved by rubbing with the hand, followed by tasteless eructations and passage of flatus, 43.
Pinching-pressive sensation in the left side of the upper abdomen, extending to the region of the hip, relieved for a short time by eructations, 52. [530.]
Cutting pain in the lower right side of the abdomen, afterwards in the upper left side, though not like the previous cutting in the intestines; indeed it was not in the intestines, 34.
Sensation of cutting in the abdomen (fourth day), 36.
Constant sensation of cutting in the abdomen (fifth day), 36.
Transient stitches transversely through the abdomen, 39.
Tearing in the abdomen just to the left of the right hip, 52.
Several cutting tearings in the right side of the upper abdomen, 52.
Colic, 60.
Colic and diarrhœa, immediately after rising, 41.
Colic-like pains and vomiting, with diarrhœa, 77.
Violent colic, 80. [540.]
Violent colic and frequent vomiting through the night, 19.
A pressing-out colic during supper, just beneath the pit of the stomach, relieved by eructations, 52.
A pain, as from internal soreness, even on touch, between the left hip and ribs, 52.
Sensation of pulsation in the abdomen and chest, like a great rush of blood to the chest (second morning), 40.
Hypogastrium.
Irritation in the lower abdomen and anus, as from diarrhœa, after dinner; urging to stool, with aching in the abdomen, 35.
Frequent and constant colic in the lower abdomen, as with diarrhœa, and almost involuntary passage of slimy, watery stools, 35.
Pressure in the ileum to the left of the navel (after two hours), 37.

RECTUM AND ANUS

Rectum.
Prolapsus of the rectum, 63.
Sensation as of diarrhœa, preceded by cutting pain, without watery or thin evacuations, 35.
Slight throbbing smarting in the rectum, 39.
Anus. [550.]
Spasms in the sphincter ani, with chilliness running up the back, followed by urging to stool without being able to sufficiently evacuate the bowels, 51.*
Sensation in the anus as of diarrhœa; copious evacuations, not thin, followed by sensation as of diarrhœa in the rectum, with sore pain in the anus, 35.
Sensation of warmth and slight prickling in the anus, 27.
Very painful anus, 63.
Burning in the anus, 52.
Intermitting burning in the anus, 52.
Transient stitches in the anterior part of the anus, in the urethra, and in the left hip, 27.
Fine sticking tearing in the anus, 52.
Pain in the sphincter, as if it would be torn, with a hard stool, 35.
Crawling and violent jerking in the anus, 52. [560.]
Sudden severe itching in the anus, 27.
Urging.
Urging to stool in the afternoon, followed by an evacuation which was extremely painful, and had to be accomplished with great care, since it seemed as though the whole sphincter would be torn asunder, 35.
Urging to stool, relieved by frequent passage of flatus, 27.*
Urging to stool, with rumbling in the abdomen and pressure in the epigastric region (after eight hours), 71.
Urging to stool, with passage of flatus (third day), 27.
Urging to stool, with passage of some hardened fæces, or even no passage at all, with pain in the anus, several times during the day, 54.
Considerable urging to stool, which is unsatisfactory, 38.*
Much urging to stool, which is difficult to pass, though soft, and is followed by pain in the small of the back (fifth day), 36.
Frequent urging to stool, without result, 10.
Frequent urging to stool and some rumbling in the abdomen, but without result, 11. [570.]
Constant urging to stool, without result (third day), 26.
Constant urging to stool, with very copious evacuation and very violent griping pain, followed, after a quarter of an hour, by a sensation of much motion in the colon, after which there were six copious, watery, yellow evacuations, 4.
Ineffectual urging to stool; the rectum seemed quite inactive; nothing was accomplished, although the fæces were felt in the rectum, 35.
Very painful urging to stool; at first only a little fæces passed, but afterwards there followed a transparent, gelatinous, and very membranous mucus, with some relief of the pain in the abdomen (after three hours), 3.
Inclination to diarrhœa, 55.
*Tenesmus, 67, 77.
Constant tenesmus, with evacuation of only a small quantity of fæces, 13.
Much tenesmus with stool, 74.
She was frequently obliged to go to stool, without being able to pass anything; preceded by colic, 51.

STOOL

Diarrhœa.
Diarrhœa consisting of mucus like rice-water, 84. [580.]
Incessant diarrhœa, 63.
Bilious diarrhœa, afterwards mixed with white membranous pieces, 14.*
Watery diarrhœa, 51.
Severe purging of bilious fluid (after three hours), 83.
Dysentery; the evacuations slimy and bloody, with tenesmus, 68.*
Frequent stools, 9, 66.
Frequent stools and vomiting, 18.
Frequent stools, alternating with vomiting, 18.
Frequent liquid stools, with gripings in the abdomen, 76.
Stools watery, frequent, 85. [590.]
Stool frequent, offensive, consisting of orange-yellow slimy fluid, mingled with many bright yellow flakes, without any fæces, 17.*
Frequent evacuations from bowels, with pain; discharges large and watery; colored with bile resembling the matter vomited (after four hours), 82.
Several large watery evacuations, accompanied by severe griping pain at each discharge (after four hours), 82.
Two stools during the first night, 28.
Two unusually easy stools (second afternoon), 25.
Two pasty stools during the day (third day), 37.
Four yellow, watery stools (first day), 5.
Stool and urine passed involuntarily (after three days), 20.
Stool often involuntary during the first night, but not bloody, 21.
Frequent watery stools, without any sensation, 51. [600.]
Stools profuse, liquid, becoming involuntary before death, of a black color, and of an extremely offensive odor, 67.
Copious yellowish watery stools, 69.*
Stools yellow, bloody, thin, 80.
Stools watery, yellow, 77.
Watery stools, without any pain, 8.
*Discharges from bowels containing a large quantity of small white shreddy particles (after twenty hours), 83.
Stools without tenesmus, offensive, orange-yellow, slimy fluid, with many bright-yellow flakes, without fæces, 65.
Bloody stools, with gripings in the intestines, 61.
Semi-diarrœalike stool in the morning following the usual stool (second morning), 46.
Very copious thin yellow stool, preceded by some pain, with rumbling and sensation of moving about in the abdomen; these sensations returned soon after the stool, with urging to stool without result, 11. [610.]
Soft stool, with slight tenesmus (after nine hours), 71.
Pasty stool, 39.
Pasty stool, with flatulence, after dinner, followed by emission of offensive flatus (after six hours), 39.
Thin stool, preceded by colic, 51.
A thin watery stool passes, without any sensation, 51.
Stool thin, watery, frothy, painless, 11.
Stool as thin as water, frothy, without pain, 10.
Stool thin, yellow, pasty, evacuated with force; during the stool and afterwards an uncomfortable almost painful sensation in the abdomen, 11.
Stool thin, yellow, copious, followed by some pain, with rumbling and movings in the abdomen, together with some tenesmus, 10.
Stool thin, yellowish, pasty, evacuated with great force, accompanied by an uncomfortable almost painful sensation in the abdomen, 10. [620.]
Slimy stool, with great pressure and tenesmus, in the afternoon (third day), 74.
Stool watery, slimy, brownish-black, of a serpentine look, feculent, as though mixed with fresh bile or fresh blood, 10.
Stool very watery, slimy, greenish-black, offensive, smelling like fresh bile, or fresh blood which has stood for some minutes in a water-bath, 11.
Stool offensive, rather liquid, containing small pieces of a white membrane (after twelve hours), 18.*
Stool, with tenesmus and sensation as in diarrhœa, 71.
Passage of much offensive fæces (third day), 26.
Constipation.
Constipation (third day), 33.
Constipation for several days, and when the stool appeared it was very small, not in proportion to the amount eaten, 52.
Constipation, with sensation of fulness in the rectum (third day), 44.
Stool very sluggish and scanty, 26. [630.]
Stool, soft difficult to discharge; a portion of it remained in the anus, 34.
Stool not hard, but more difficult to pass than usual (second day), 44.
The stool not hardened, but very scanty; was evacuated with great exertion, 52.

URINARY ORGANS

Urethra.
Burning through the whole urethra, with slight contraction of the neck of the bladder on urinating (after nine hours), 71.
Slight burning in the urethra (third day), 33.
Violent burning in the urinary passages, 63.
Intolerable crawling burning in the urethra, in the morning, in bed, after urinating, with sensation as though more urine would pass, and burning when passing a few drops, as if it were glowing hot; together with burning in the anus (same pain repeat after eight days, also in the morning, in bed), 52.
Burning sensation in the urethra, as if it were sore, on urinating, 51.
Drawing and tearing in the urethra, 51.
Pressive drawing in the urethra, 52. [640.]
Drawing sensation in the lowest portion of the urethra, 52.
Drawing pain in the urethra, 51.
Cutting in the forepart of the urethra, 52.
Slight cutting on micturition (third day), 33.
Tickling in the navicular fossa, 39.
Urging to urinate, 37, 55, 70.
Great urging to urinate, 27.
Micturition.
Frequent micturition, 20.
Frequent micturition, day and night (third day), 27.
Frequent deep-yellow urine, more profuse than usual, 39. [650.]
Micturition more frequent than usual, 52.
Diabetic urine was passed every half hour (after two weeks), 20.
Increased secretion of urine, 51.
Increased dark-colored urine, 70.
Urine somewhat increased during the first twelve hours, with some urging therewith, 54.
Urine copious, golden-yellow, clear, afterwards with white floating clouds (third day), 33.
Urine profuse and hot, 27.
Urine profuse, turbid, with a specific gravity of 1034 to 1014, 69.
Diminished micturition, 63.*
Urine scanty, 85 ; (after fifteen hours), 67.* [660.]
Urine scanty, fiery red, and burning (after three hours), 3.
Urinary secretion scanty, 16.
Retention of the urine, 77, 80.
No urine, 76.
Urine.
Urine darker than usual, 55.*
Brown-black urine, 64.*
Bloody urine, with strangury, 70.*
Urine at first turbid, then clear and yellow, 52.
Urine like lime-water; the turbidity caused by urate of ammonia, 69.
Colchicum has no remarkable action upon the excretion of urine; when a diminution of the constituents of the urine is noticed, it is associated with increased evacuations of the bowels, 10. [670.]
In two provers the solid constituents, and especially the nitrogenous portions of the urine, were diminished; the fæces, however, were more copious than natural during both provings, which may account for the diminished constituents of the urine, 22.
Uric acid was decidedly increased while using Colchicum, 24.
Decided increase of uric acid (during four observations), 23.
Decided increase of uric acid, and also of the urea, 14.
The uric acid disappeared entirely during the proving, 22.
The urea was in three provings increased, as also the fixed salts, while the whole amount of urine was diminished, 23.
He excreted 1.02 grammes of nitrogen daily less than the normal, corresponding to 2.18 grammes of urea, 13.
Fixed salts seemed to be increased, earthy phosphates diminished, 22.

SEXUAL ORGANS

Male.
Tearing in the glans penis, 52.
Very sensitive fine pains in the left testicle, as if crushed, only noticed when stepping on the left foot; apparently caused by the jar, since it was not noticed on pressure, 34. [680.]
Tearing in the left spermatic cord, 51.
Excessive and unusual desire for coition (second day), 26.
Excessive sexual desire, after eating, 27.
Female.
Menstruation some days too early, 41.
Menstruation seven days, earlier than usual, 53.
Menstruation that had just appeared, disappeared, 51.

RESPIRATORY ORGANS

Larynx, Trachea, and Bronchi.
While swallowing the tincture, the air-passages became irritated by it, causing a slight dry cough, 2.
Pain in the larynx, with croupous expectoration from it, 35.
Pressive pain in the muscles above the larynx, somewhat to the left side, internally and externally, 52.
Scraping in the larynx (soon), 33. [690.]
Tickling in the larynx, 33.
Crawling in the trachea and in the chest, with cough, 52.
Voice.
Hollow, deep voice, 33.
Slight hoarseness (soon), 33 ; (second day), 32.
Loss of voice, as in cholera, 76.
Cough and Expectoration.
(Cough alternating with coryza), 26.
Cough and deep respiration (second day), 25.
Frequent easy expectoration from the larynx, of mucus in gelatinous or starchlike lumps, without any cough, 35.
Respiration.
Notwithstanding the transpiration from the skin and the evacuation of the bowels were increased in quantity, the carbonic acid expired by the lungs remained about the same, and, on one day, was much above the normal, 11.
Irregular respiration (after three days), 20. [700.]
Respiration continued intermitting; convulsions became more frequent involving, the neck and face, and the jaws became more firmly clenched, with frothing from the mouth and distortion of the eyes (after six weeks), 20.
Desire to take frequent deep inspiration, 27.
Difficult breathing, 63, 65.
Difficult breathing, and great anxiety (after eighteen hours), 17.
Dyspnœa, 63.
Dyspnœa, and contraction of the chest, 69.
Extreme dyspnœa, 75.

CHEST

Feeling of orgasm in the chest, and a peculiar sensation as if something alive were working in it; frequently through the day, but especially in the evening, after eating (second day), 40.
Transient anxiety in the chest, especially in the left side (fourth day), 71.
Fulness and oppression of the chest (fourth day), 44. [710.]
Sensation of fulness in the chest, with pulsations in the abdomen, 39.
Frequent tensive sensation in the chest, 52.
Constriction of the chest, 78.
Some constriction of the chest, with necessity for breathing deeply (after nine hours), 39.
Frequent constriction of the chest, with sticking and boring pains through the chest, always worse beneath the left nipple, 72.
Sensation of constriction in the chest, 65.
Sensation of constriction in the chest, with difficult breathing (after five hours), 17.
Pressive pain in the chest, the whole day, 54.
Pinching-pressive sensation in the chest, 53.
Oppression of the chest, 84. [720.]
Oppression of the chest, while walking (second day), 44.
An alternating oppression of the chest (after half an hour), 54.
Anxious oppression of the chest, lasting the whole day (after three hours), 54.
Feeling of oppression of the chest, 75.*
Stitches in the pectoral muscles, on moving the thorax, 33.
Frequent stitches here and there in the chest, piercing, though without affecting respiration (fifth day), 40.
Cutting-tearing pains across the chest, 34.
Front.
Drawing-boring pain, extending from the middle of the sternum to the left nipple; the pain was transient, but was felt here and there in the right side of the chest; also, though much worse in the left, it was not only not aggravated by deep inspiration, but was rather relieved; it afterwards extended over the whole chest and caused a sensation of constriction there as if a heavy weight were lying upon it, 72.
Feeling as if the sternum and spine were screwed together; the pressure commences on the sternum, 71.
Short stitches beginning in the anterior wall of the chest, and shooting through to the posterior wall (fourth day), 71.
Sides. [730.]
Twitching in the right pectoral muscles (soon), 33.
Such violent pains around the right side of the thorax on writing, that I was obliged to cease, 34.
Boring pains in the left side of the chest, which were especially violent at night, about 10 o'clock, and the tightness of the chest became so severe that he could with difficulty get his breath, and immediately became very anxious, 72.
Sudden violent constriction in the right side of the chest, causing me to start up, 34.
Spasmodic compression of the left half of the chest, with difficult respiration (after nine hours), 71.
Intermitting pressure, now in the upper, now in the lower part, in small places, in the right side of the chest, 52.
Dull sticking pressure in the upper part of the right side of the chest, near the arm, 52.
Slight oppression in the left side of the chest, starting from the heart, necessitating deep inspiration, 27.
Cutting pain in the forepart of the left side of the chest, lower portion, on blowing the nose, 34.
Cutting pain in the left side of the chest, not affecting respiration, 34. [740.]
Cutting or pinching pains in small spots, sometimes on the right side, in the anterior and lower portion of the chest, sometimes deep in the hepatic region, and then again on the left side in the region of the spleen, 34.
Very violent cutting pain, as if with sharp knives, in the right side of the chest, almost taking away the breath and causing her to cry out; these very violent pains lasted about a quarter of an hour, and then diminished to a slight cutting in the chest; it seemed as if the sharp cuttings which were constantly felt did not penetrate deeply nor affect the less sensitive portions (fourth day), 36.
Pinching-cutting pains, here and there, in the anterior and lower portions of the left side of the chest, 34.
Dull sticking, deep in the left side of the chest, on complete expiration, but not on inspiration; soon afterwards, however, only on inspiration, 52.
Momentary sticking, rheumatic-like pain in the right wall of the chest, 38.
Stitches in the right side of the chest, 45.
Stitches in the left side of the chest, near the eighth rib, 73.
Stitches in the right lower side of the chest, in the lungs, 35.
Stitches in the left side of the chest, on inspiration, and also, though less, on coughing, 52.
Transient stitches beneath the left clavicle (after eleven hours), 39. [750.]
Dull stitches in the right side of the chest, 52.
Violent stitches from within outward, in the right side of the chest, 52.
Violent stitches in the upper part of the left side of the chest, 52.
Dull sticking tearing very deep within the right chest, where it is difficult to distinguish whether it is more in the back whence it seems to extend, or more in the chest, 52.
Several violent stitches in the left side of the chest, in the morning, in bed, also later on some physical exertion, 52.
Sharp, pointed stitches in the right side of the chest, 52.
Burning stitch, as if external, on the right side of the chest, 52.
Sore pain in the region of the left nipple, in a small spot scarcely an inch across, deep in the chest, very sensitive, more painful on inspiration, the deeper the inspiration the more painful the place; relieved after rising from bed, 35.
Dull tearing pain in the right side of the chest, near the axilla, afterwards becoming a sore sensation, even on touch and motion, 52.

HEART AND PULSE

Præcordium.
Slight momentary beating, and transient stitches, in the præcordial region, 27. [760.]
Fulness and oppression, as from stagnation of blood, in the heart, at night while lying on the left side, so that he was obliged to lie on the right side, 38.
Pressure and anxiety in the præcordial region, 16.
Pressure and oppression in the præcordial region, with a feeling as if he would be attacked by apoplexy, relieved by walking around (fourth day), 37.
Transient pressure in the præcordial region, in the afternoon (first day), 26.
Oppression of the heart, 33 ; (soon), 32.
Oppression in the præcordial region, with slight beating of the heart (second day), 25.
Slight oppression in the præcordial region, 27.
Stitches in the heart, 45.
Transient stitches in the præcordial region (soon), 33, 45.
Tearing in the præcordial region, 52. [770.]
Præcordial region sensitive to pressure, 49.
Palpitation, 31, 59 ; (soon), 32.*
Palpitation in the afternoon, 28.
Periodic palpitation, with oppression of the heart (second day), 32.
Palpitation, on waking (third day), 33.
Violent palpitation, 51.
Violent palpitation of the heart, on going to sleep (from 12th dil.), 41.
Audible palpitation, at night, 32 ; (second day), 33.
Some dull, irregular, seemingly suppressed beats of the heart, with a peculiar, indescribable sensation in the chest (soon), 34.
Beating of the heart scarcely perceptible, with however, very perceptible pulsation in the abdomen, 39.
Pulse. [780.]
Rapid pulse, 76.
Pulse rapid, 3, 39.
Pulse rapid, small, not intermitting, 85.
*Pulse small, rapid, 18, 60.
Pulse small, and somewhat accelerated (after twelve hours), 18.
Pulse weak, between 80 and 90, 80.
Pulse large, full, and hard; from 90 to 100 beats in a minute, 51.
Pulse 170; weak, and thready, 69.
Pulse 190 (ninth day), 20.
Pulse after taking (third dose, third day) 50; after an hour 60; next morning 60; at noon 70, 29. [790.]
Pulse slow, 66 (soon), 32.
Pulse slow, 61 (soon), 33.
Pulse slow, 45 and very feeble (after four hours), 82.
Pulse small, slow weak, 67.
Pulse weak and slow, as long as the nausea continued, 9.
Pulse small, slow, and weak, 13.
Pulse thready, very slow, 78.
Frequency of pulse diminished ten or twenty beats in a minute (after twelve hours), 81.
Pulse 70 before taking, two hours afterwards 60; twelve hours afterwards, in the evening, 65 (from the 3d dil.), 28.
Pulse before taking 70; after two hours 65; very weak; after twelve hours in the evening 57; in an hour afterwards 70, 29. [800.]
Pulse weak and slow during the first twenty-four hours, afterwards 100 for twenty-four hours, without any morbid symptoms, except weakness, 7.
Pulse 108, weak, irritable, very irregular, at times rapid at times slow, 48.
Pulse intermitting, scarcely perceptible (after fifteen hours), 67.
Contracted, spasmodic pulse, 80, 17, 65.
Pulse small, 177.
Pulse small, contracted, 19.
Pulse small and tense, 16.
Pulse small, scarcely perceptible, 84.
Pulse smaller and smaller, more contracted, 75. [810.]
Pulse not perceptible; but after some hours, it became thready and tremulous, 20.

NECK AND BACK

Neck.
Visible throbbing in the cervical arteries, especially noticed on sitting still, 39.
Paralysis of the muscles of the neck, so that when the child was raised up, the head fell backward, with the mouth wide open (ninth day), 20.
Rheumatism in the neck, especially in the right trapezius, which is so painful that when he makes a wrong movement of the neck, he is obliged to cry out, lasting two or three weeks, 71.
Great stiffness and pain in back of neck and occiput, aggravated by moving the head (third day), 83.
Pains and stiffness in the neck and occiput (third day), 14.
Pains in the nape of the neck, 84.
Burning on the right side of the nape of the neck, externally, 52.
Tensive pain in the right cervical muscles noticed externally and on swallowing (after half an hour), 54.
Pressive pain in the upper part of the neck, beneath the ear, near the articulation of the jaws; with some soreness to the touch, 52. [820.]
Some stitches in the cervical muscles, 51.
Back.
Drawing backache when lying quiet, better when moving (second day), 32.
Tearing in the back to the left of the spine, 52.
Dorsal.
Pain in the scapulæ, coming from the chest; on sitting a long time (fifth day), 40.
Very severe rheumatic pains in the scapulæ and nape of the neck, mostly tensive and pressive alternating, preventing free motion of the neck, especially turning it to the left side or stretching it far backward, 35.
Rheumatic pain, pressive periodic; more in the scapulæ than in the nape of the neck, 35.
Constant dull stitch on the superior left angle of the right scapula, 52.
Violent, pressive, dull, constant stitch beneath and between the scapulæ, in the back, 52.
Lumbar.
Pains in the lumbar region, 54.
Dull pressure on both sides of the lumbar vertebræ (after nine hours), 7. [830.]
Constant sticking-tearing pains in the lumbar region, 34.
Violent writhing in the region of the loins and urinary passages , with constant desire to urinate (after two hours), 3.*
Feeling of heaviness in the small of the back, with sensation as if the rectum were stuffed, 39.
Pain in the small of the back, 45.
Drawing in the small of the back, on waking, 39.
Drawing in the small of the back, aggravated by motion, 51.
Slight drawing pain in the small of the back (third day), 33.
Sticking stitches in the small of the back, 51.
Bruised feeling in the small of the back, in the morning, 39.
(Bruised pain in the small of the back), 25, 26 . [This symptom, which frequently recurs during the provings of this individual, is only noticed to reject it, since it was one of the usual symptoms before the proving. -T. F. A.] [840.]
(Bruised pain in the small of the back disappears), 25 . [This is curative, since the prover usually suffered from rheumatic pains in the small of back.]
Tension in the region of the kidneys, 70.
Sacral.
A constant pain in the sacrum woke him frequently at night (first night), 37.
Pressure deep in the sacrum, in the afternoon (first day), 37.
Sticking pain in the region of the sacrum and coccyx, 45.
Constant pressive pain at the union of the last vertebræ with the sacrum, increased by standing or walking, 37 . [Had formerly been observed (before the proving) as a rheumatic affection.]
Burning stitches in the sacrum, 52.
An excessively painful spot as if suppurating, in the middle of the sacrum, of the size of the palm of the hand, which aches intolerably on the slightest touch, 51.
Pain in the back, just above the anus, with a warm itching burning sensation, as from a blister; that portion of the skin seemed sensitive to slight touch, but not to hard pressure; inclination to scratch it, which relieved and caused some redness, 27.

EXTREMITIES IN GENERAL

Objective.
Left elbow and knee-joints swollen, hot, painful, while the right side was partially paralyzed and nearly devoid of sensation, 20. [850.]
Toes and fingers painfully flexed at times (after eleven hours), 83.
Slight twitchings in the limbs, 85.
Jerkings, as from electric shocks, in all the limbs, especially in the metatarsal joints (after twenty-four hours), 71.
Trembling of the limbs that increased to an attack of violent convulsive movements (after eight hours); three hours later, a similar paroxysm occurred, ending with two attacks of vomiting, 20.
Trembling in the extremities; these motions became more violent and convulsive, with flow of much whitish froth from the mouth; the attack was after a quarter of an hour similar to opisthotonos; after a quiet sleep, from 11 to 2 at night, another attack of a similar kind and duration, 20.
Weakness of the limbs, so that she was unable to walk, 79.
Weakness in the limbs, in the morning, 28.
Great weakness, faintness, sleepiness and prostration in all the limbs, with disinclination to work, 11.
Paralysis of the right foot and left arm, 20.
The limbs feel weary in the morning, 74. [860.]
Feeling of weakness and prostration throughout the limbs, 73.
She experienced such great weakness in the muscles of the extremities, that she thought she would fall, 51.
On attempting to walk, the limbs seem to have lost their power, 67.
Numbness of feet and hands, succeeded by a prickling feeling, as if "they had been asleep" (after eleven hours), 83.
Uneasiness in all the limbs, at night (fifth day), 36.
Pain in the limbs, 84.
Pains in all the limbs, 77.
All the joints of the fingers and toes, and also the wrists and ankles, were very painful (after eleven hours), 83.
The most remarkable feature of the case was the intense rheumatic kind of pain in the hands and feet, which began first, and continued during the origin and progress of the affection, becoming very severe, so much so that she could not bear to have her finger-joints pressed nor extended from their semiflexed condition, 83.
The shoulders and knees are painful during rest, better during motion; uneasiness, obliging him to move the limbs constantly (first day), 33. [870.]
Violent drawing pains in the shoulders, limbs and spine (after six days), (after antidotes). Ultimately, almost all the bones and joints were affected with pain, which was of a gnawing-dragging character, 83.
Sometimes sticking, sometimes jerking drawing (especially in the morning), now in the muscles of the shoulder, now in the hip of the right side, 51.

SUPERIOR EXTREMITIES

Objective.
Right arm and hand paralyzed, with the thumb drawn inward, the rest of the fingers being spasmodically closed over it (after four weeks), 20.
Subjective.
Sensation of weakness in the right arm, at noon, 33.
The left upper and forearm felt lame, weakened, 27.
Sensation of paralysis in the whole of the left arm, 71.
Arms feel heavy, 73.
*A paralytic pain in the arms, so violent that he cannot hold the lightest thing firmly, 51.
Tearing in the arms, with paralyzed sensation, 73. [880.]
Cutting-tearing pains in the left arm, 34.
Shoulder.
Pain in the shoulder-joint (second day), 14.
Pain in shoulder-joints, followed by pains in hips and loins; it increased in intensity so that she said she thought she should go mad (after eleven hours), 83.
Pinching pain on the left shoulder, 52.
Tearings in the right shoulder (second day), 33.
Dull tearing pressure in the right side beneath the axilla, 52.
Frequent tearing-pressive pain, now in the right, now in the left axilla, 52.
Tearing in the right shoulder and right forearm, 71.
Transient stitches in the right shoulder (after five hours), 39.
Pain in a small spot beneath and almost in the right axilla, as after a blow, 52. [890.]
Severe bubbling sensation in the left axilla, even perceptible externally, 52.
Arm.
Sensation of pressure in the left upper arm above the elbow, which, during the afternoon, became a violent pain on moving the arm, especially on raising it, so that it was impossible to put on my coat alone; not felt when at rest, nor during the night, 42.
Burning-pressive pain on the inner side of the left upper arm near the axilla, 52.
Very sensitive tearings in the left upper arm, 35.
Elbow.
Tearing on the inner side of both elbows, extending from the upper arms, 52.
Transient stitches in the left elbow, soon, 33.
Long stitches in the left elbow, after which the place was sensitive to touch, 34.
Forearm.
Constant complaints of pain in both forearms (second day), 20.
Pains in both forearms, which were very sensitive to the slightest touch (after sixteen hours), 20.
Drawings from the left thumb up along the whole radial surface of the forearm, 71. [900.]
Tearing in the forearm near the wrist, 52.
Tearings in the flexor surface of the whole of the left forearm, extending up to the elbow-joint, 71.
Very sensitive tearing on the extensor surface of the forearm, as if some of the nerves were torn, at intervals, 34.
Fine tearings in the extensor surface of the left forearm, extending into some of the fingers, 34.
Very sensitive fine tearing in the right forearm, especially on the outer side of the muscles, without being affected by rest or motion, 35.
Very fine piercing tearings on the extensor surface of the forearm, extending into the fingers, as from electric shocks, 34.
Tearing pain on the outer side of the left forearm, as if in the fascia, 34.
Jerklike tearing pains, extending from the elbow into the wrist in the right arm; this was frequently repeated, but lasted only a second each time; afterwards a similar pain extended from the wrist to the tips of the fingers, 72.
Bubbling sensation on the outer side of the left forearm, 32.
Wrist.
Pain in the right wrist (soon), 20. [910.]
Sticking and heat in the left wrist (volar surface), afterwards in the right wrist, 38.
Slight stitches in both wrists and elbows (first night), 32.
Tearing in the right wrist, 52.
Hand.
Spasmodic contraction of the hands, so that the fingers were stretched out and the ball of the thumb turned into the palm, 50.
Trembling of the hands, 48.
The right hand is so tremulous that it almost prevents writing, 52.
The hands feel so powerless that it seems as though she could not avoid letting objects which she held fall to the ground, 73.
Pains in the left metacarpus, especially between the third and fourth fingers, on motion, especially on flexion of the hand, 43.
Constant drawing in the hands, extending into the fingers, 73.
Tearing on the back of the right hand, 52. [920.]
Tearing in the right hand and beneath the last phalanx of the little finger; at times very violent, 52.
Sticking tearing, especially in the lower portion of the right hand, 52.
Fingers.
Tips of the fingers and nails blue, 84.
Nails blue, 68.
Fingers spasmodically flexed, though in constant motion, 84.
The third and fourth fingers of the right hand are drawn inwards, 51.
Rheumatic drawing in the metacarpal joints of the right thumb, 52.
Pressive drawing in the posterior portion and ball of the right thumb, 52.
Pain in the metacarpal joint of the right thumb, as if a splinter were sticking in it, 52.
Pain in the tips of the fingers on the volar surface, as from a splinter, 34. [930.]
Stitches in the left thumb (after one hour and a half), 39.
Tearing in the joints of the right fingers, 52.
Tearing beneath the nail of the left index finger, 52.
Tearing in the metacarpal bones of the right middle and ring fingers, 52.
Tearings in the left little finger, 34.
Tearing in the last phalanges of the little and ring fingers of the left hand, 52.
Sticking tearing in the ligaments of the right little finger, 51.

INFERIOR EXTREMITIES

On attempting to walk, it seems as though he would lose the use of his limbs, 13.
Hip.
Slight snapping in the left hip, 27.
Sensation as of something living in the left hip, 27. [940.]
Pains in the hips and loins (third day), 14.
Drawing in the hip-joints (soon), 33.
Slight drawing pain in the hip-bone, on moving about at night (second day), 32.
Pinching pressure on and above the right hip, 52.
Transient stitches in the hips, especially in the left, 27.
Tearing in the region of the hip, 52.
Slight tearing in the right hip-joint, extending through the thigh to the knee (after seven hours), 71.
Drawing tearing deep in the region of the left hip, which seems to have its seat in the ligaments; worse at night, 51.
Thigh.
Thighs abducted, 80.
Stiffness of the left thigh, making walking difficult, 71. [950.]
Pinching in the thigh like a cramps, as if it were asleep, 52.
Drawing deep in the muscles of the thigh, 51.
Drawing pains in the left femur, at times worse, at times better, as from excessive fatigue, or like growing pains, 34.
Sudden sticking-drawing pain beneath the left nates, extending into the perineum, lasting half a minute, 39.
Severe paralytic drawing in the whole of the right thigh, in the evening in bed, 52.
Pressure upon the bones of the thighs; the middle portion is especially painful, 35.
Tearing in the thigh, extending towards the hip, 52.
Tearing in the upper part of the left thigh, 52.
Tearing high up on the inner side of the right thigh, 52.
Tearing deep in the nates towards the anus, 52. [960.]
Tearing in the middle of the left thigh, in the evening, in bed, 52.
Jerking-like tearing in the upper portion of the right thigh, 52.
Transient tearing shooting from the left hip-joint to the leg, 52.
Knee.
Slight momentary snapping on the left surface of the right knee, 27.
The knee feels broken (weary) on going up steps, 27.
The right knee-joints is painful, in the evening, in bed, with sensation as if it were paralyzed (fifth day), 71.
Painful sensation in the bend of the right knee, extending down the calf, where it was tensive; during a long walk, 43.
Very violent constant pain in the left knee, 75.
Pressive pain in the inner side of the right knee, 52.
Transient stitches in the knees and ankles (first day), 32. [970.]
Tearings just below the patella, 34.
Tearing pain just above the left knee, in the evening, in bed, 52.
Tearing pains beneath the patella, posteriorly, 34.
Stitches in the knee-joint (second day), 33.
Leg.
Pains in the legs, 76.
Pains in the calves and feet, 19.
Pain on the forepart of the tibiæ, like a chilliness in the bones, not relieved by warmth, 34.
Violent pain in the forepart of the leg, as from chilliness, especially on the tibia, with coldness of the lower legs, even in bed, 34.
Very sensitive pain in the forepart of the tibia, a dull pain, feeling as if the bone were chilled, or like growing pains, 34.
Cramps in the legs, 69.* [980.]
Drawing in both calves and in the right metatarsus (after seven hours), 71.
Tearing in the lower portion of the right calf, 52.
Tearing in the left side of the left calf, 52.
Tensive tearing on the left lower portion of the left tibia, 52.
Pinching-tearing pain at the insertion of the right tendo Achillis, 34.
Ankle.
Tearing in the left tarsal joints, 52.
Painful pressure in the right external malleolus, as from fatigue, at 8 P.M. (first day), 37.
Foot.
Weakness of the feet (soon), 33.
Sensation of weakness in the feet, 30.
Great heaviness of the feet, extending down into the lower legs (second day), 44. [990.]
Cramp in the feet, 77.
Very painful cramps in both feet , especially in the left, 75.
Tearing in the feet, feeling as if they were paralyzed, 73.
Tearings through the whole of the left foot, 73.
Tearings on the inner side of the metatarsal joints, 34.
Tearing on the back of the left foot, 52.
Drawing tearing on the right instep, 52.
Violent painful cramps in both plantar regions (soon), 78.
Tearing in the sole of the left foot, not far from the toes, 52.
Tearing on the inner curvature of the right foot, between the ball of the great toe and the heel, 52. [1000.]
Tearing in a small spot in the forepart of the right foot, three finger's breadth from the malleolus, near the sole of the foot, 52.
Drawing tearing in the sole of the left foot, 51.
Tearing pains in the sole of the left foot, in a small spot in the metatarsus, 34.
Tearing in the right heel near the sole, 52.
Toes.
Pain in the left great toe, as though the nail would enter the flesh, 52.
Pressive-drawing pain in the whole of the left great toe, afterwards also in the right, and then in the left middle toes; the pain seems to be more on the lower surface of the toes, 52.
Sticking-drawing sensation in the right great toe, 39.
Very sensitive, sharp, boring stitches across the top of the nail, at the tip of the right great toe, 52.
Sticking tearing in the ball of the right great toe, near its lower side, 52.

GENERAL SYMPTOMS

Objective.
The solid constituents of defibrinated blood were diminished, as also was the absolute amount of blood-corpuscles and of the plasma, 22. [1010.]
The quantity of colored corpuscles in the blood was somewhat diminished, 11.
The gait is very unsteady and tottering, partly on account of weakness, and partly on account of sudden sticking-tearing jerks which shoot through the periosteum, always with a sensation of paralysis, and with actual transient paralysis, 51.
Stretching, 39.
Convulsions; the right arm could not be extended, the left could not be flexed; both feet were drawn upward; the soles formed a half circle, and the toes were spasmodically drawn inward (after seven weeks), 20.
Convulsions of the left side and muscles of the face (tenth day), 20.
The patient gradually developed convulsions, in which the extremities were spasmodically flexed; fingers and toes flexed; the eyes convulsively rotated; the left hand, which constantly kept hold of the penis, trembled; the convulsions became more and more frequent, extending to the muscles of the neck; the lower jaw became firmly pressed against the upper; and the patient frothed at the mouth, 20 . [The remaining symptoms noted during the progress of this case, subsequent to the administration of antidotes. Tartar emetic, Ipecac, etc., have not been taken.]
Weakness, 39.
Weakness, as after exertion, 55.
Weakness and weariness the whole day, disappearing in the evening, 13 ; (fifth day), 10.
Great weakness in the morning, 37. [1020.]
Great weakness and exhaustion, 69.*
General weakness, 39 ; (soon), 33.
Sudden sinking of the strength, so that after ten hours he was scarcely able to speak or walk across the room, 51.
Painful loss of power in the muscles, especially about the knee-joints, so that the knees frequently give way, particularly on raising the leg to step over a high object, as for example, over a doorstep, 51.
He is quite powerless, and the whole body feels paralyzed, especially the arms, 51.
Exhaustion, 50.
*Great exhaustion, 19, 80 ; (second evening), 21.
General prostration, 19.
Great prostration and weakness (after twenty-four hours), 71.
Complete paralysis of the right side with only slight sensation; the toes were on the slightest touch drawn towards the sole (ninth day), 20. [1030.]
Faintness after a copious stool, 7.
Restlessness, 11.
Extremely restless, constantly turning the head from left to right (second morning), 20.
Uneasiness, 85.
Great uneasiness (after sixteen hours), 20.
Subjective.
Very sensitive to the slightest touch (second day), 20.*
Disinclination to work, 39.
Weariness in the morning on waking (second day), 32.
Great weariness in the morning, on rising, 30.
Great weariness, indolence, sleepiness, prostration of the limbs, and disinclination to work after a stool, 10. [1040.]
Very great weariness and prostration, 16.
Sensation of weariness on ascending steps (after ten minutes), 27.
Sensation of weakness over the whole body; the feet feel weary (after five hours), 71.
Very severe distressing sensation of weakness in the whole body, while sitting quiet, with a kind of nausea in the throat, and confusion of the head; immediately relieved on moving, especially in the open air, but returning at once on sitting down, 35.
Great feeling of prostration accompanied with restlessness (after four hours), 82.
Complaints of excessive prostration, 78.*
Such great prostration of mind, such weariness, painfulness, and sensitiveness of the whole body, that he could scarcely refrain from weeping, 51.
All the muscles, especially those of the limbs seem paralyzed, 51.
Inclination to faint.
Great discomfort (fifth day), 36. [1050.]
His sufferings seem intolerable, 51.
Attack similar to cholera, with constant rice water vomiting, and similar evacuation of the bowels, which were forcible and accompanied by tenesmus, 68.
Rheumatic pain in the whole body, especially in the back, upper arms, and shoulders, in the evening, 35.
Asked is she had not got rheumatic fever. Some females in the room were also struck with the similarity of the symptoms, 83.
(Various most severe muscular pains in the legs and abdomen, less in the chest, arms, and back; they may possibly be ascribed to a five hours' horseback ride; they continued nearly eight days), 46.
A tremulous sensation in the whole body as from fasting, in the afternoon, especially immediately after dinner, 52.
Tearing tension in small spots here and there in the body, for example, somewhat below the pit of the stomach, in the ribs of the left side, a little below the axilla, in the right popliteal space, 52.
Griping and crawling in some of the toes, in the ball of the right foot, in the fingers, ears, and several places of the skin of the face, as after taking cold, or change in the weather, in the evening, 54.
Slight drawing and jerking, also tearing in the incisors, eyelids, muscles of the face, and other parts of the body here and there, 51.
Sudden tearing jerks all through one-half of the body, like electric shocks, 52. [1060.]
Frequent single tearing jerks, mostly in the left side, 54.
The pains seem to become intolerable in the evening; he could get into a rage with himself if he had the strength, 51.
Very much affected by any work, especially reading or writing (sixth day), 36.
Relieved after a dose of Pulsatilla (fifth day), 36.

SKIN

Objective.
Paleness of the skin, 77.
Skin livid, dry, and hot (second day), 20.
The whole body became scarlet-red (after a few hours), 20.
Eruptions.
Pityriasis on the inner surface of the left thigh and corresponding portion of the scrotum (after one month), 37.
(During this proving two dry wartlike pimples on the nape of the neck, lasting six weeks, and disappearing with desquamation), 32.
A small round ulcer on the vermilion margin of the lip, 34. [1070.]
Sticking in the skin, so that it jerks through the whole body, 51.
Violent jerking stitches, as from fleabites, in various places, obliging me to scratch, and then disappearing, 34.
Itching over the whole body, 30.
Itching over the whole body, as from burning nettles or from jelly-fish, 61.
Itching of the skin in various parts of the body, 51.
Burning itching in small places here and there; after scratching the skin becomes red, and the itching changes to another place, 34.
Sticking itching in various parts of the body (first day), 34.
Very burning sticking-itching, here and there, in the skin, obliging scratching, whereby it was driven to another part, 34.
Crawling on the inner surface of the great, second, and third toes of the right foot, as if they were asleep, 52.
Itching and eruption on the face, 56. [1080.]
Sensitive itching of the skin of both forearms on the ulnar side, where, without scratching, the skin becomes red, 71.
Obstinate itching of the hands, 56.

SLEEP AND DREAMS

Yawning, 39.
Yawning, with rumbling in the abdomen, after dinner, followed by very copious stool (second day), 46.
Repeated yawning (soon), 32.
Was frequently obliged to yawn, 51.
Sleepiness during the day, 51.
Sleepiness; disinclination to work; with confusion of the head (after half an hour), 54.
Unusual sleepiness in the afternoon (first day), 33 ; (second day), 32.
Unusual sleepiness in the evening (first day), 32. [1090.]
Excessive sleepiness soon after supper (after five hours), 27.
Overpowering sleepiness in the afternoon, 35.
Very sleepy till midnight, then waking with sensation of heavy oppression in the stomach, after which he was wide awake for two hours, 32.
Unusually strong desire to sleep (third night), 25.
Irresistible desire to sleep in the evening (first day), 25.
At night deep sleep, with vivid dreams and grinding of the teeth, 32.
Soporous condition for two hours and a half, 12.
The child was found in a soporous condition, lying on its back in bed, with half open eyes and loud respiration, 19.
Sleeplessness.
Sleeplessness, 76.
Uneasy sleep, 55. [1100.]
Uneasy sleep, with anxious dreams (third day), 26.
Sleep uneasy, unrefreshing, 74.
Sleep very uneasy (second day), 30.
Afternoon nap on the sofa very uneasy, only slightly refreshing, 10.
The afternoon nap did not refresh him, 11.
Sleep restless and exhausting, 71.
Sleep restless, with many dreams, 39.
Very restless night, with heavy dreams, 28.
Frequent waking from sleep in fright, with the idea that there were mice in the bed; two nights in succession, 52.
Many dreams at night (first night), 27. [1110.]
Lascivious dreams towards morning, with erections, 39.

FEVER

Chilliness.
Temperature diminished, 16.
Cold temperature of the skin, 17.
Skin cool, 65.
Cold skin and tongue, 69.
Skin tongue, and breath cold, 68.
Chilliness (soon), 33 ; (second day), 32.
Chilliness in the room, 29.
Chilliness the whole day, 10.
Chilliness of the whole body, even in the room, 34. [1120.]
Chilliness the whole day, lasting till 7 P.M., 11.
Chilliness in the afternoon (second day), 40.
Chilliness in the open air in the afternoon (first day), 25.
Chilliness in the room, soon afterwards vertigo, 28.
Chilliness and heat alternating, 65.
Chilliness and heat alternating, 17.
Chilliness, with heat of the head at night (second day), 32.
Constant chilliness (second day), 32.
Constant chilliness in the afternoon (second day), 32.
Coldness in the afternoon after dinner (third day), 10. [1130.]
General coldness, 77, 78.
Progressive coldness, 75.
Sensation of coldness, 45.
Sensation of coldness in the evening relieved by warm coverings, but returning on going to bed as a chilliness, with chattering of the teeth, disappearing after a short time while lying still; to bed as a it threatened to return on motion, 35.
General lack of warmth in the body, even in bed, 34.
Chilliness in the scalp, 45.
Chilliness in the knees, 34.
Slight chilly sensation in the abdomen, especially in the stomach, with pain and weakness, 51.
Shivering in the back (second day), 33.
Shivering through all the limbs, 51. [1140.]
Frequent shivering down the back (after a quarter of an hour), 3.
Nose, cheeks, and soles of the feet cold, 20.
Diminished temperature of the extremities, 80.
Remarkable coldness of the skin of the hands and legs, even in bed, 34.
*Cold extremities, 17, 19 ; (after four hours), 82 , etc.
Cold feet and hands, 52 ; (second day), 33.
Hands, feet, and forehead cold, 48.
Fingers cold (second day), 25.
The fingers feel cold and fuzzy, 71.
Feet cold, 67. [1150.]
Cold feet in the afternoon (second day), 40.
Heat.
Heat in the body at night, 55.
Dry heat at night, 32.
Dry heat of the skin, 51.
Some dry heat, 28.
Skin hot, 85.
Skin hot, 76.
Frequently repeated flushes of heat in the afternoon (from three to forty-four days), 46.
Fever, with gastric disturbances, 12.
Symptom of warmth, like rush of blood, through the skin of the chest and head, in bed (soon), 34. [1160.]
Sensation of warmth in the small of the back, extending into the rectum (after eleven hours), 39.
Sensation of warmth and throbbing on the side, in the small of the back, while sitting, 27.
Heat passing into headache, 39.
Heat in the anterior part of the head, 29.
Flushes of heat in the head (after a quarter of an hour), 3.
Great heat of the face, 41.
Flushes of heat rising up along the spine in a warm room, 27.
Sensation of flushes of heat in the hands and feet, 73.
Palms of the hands hot (second day), 25.
Burning externally on the right side, near the pit of the stomach, 52.
Sweat. [1170.]
Increased secretion from the skin, 69.
Sweat, 55.
Slight sweat at night (first day), 33.
Slight sweat on waking after midnight (first day), 32.
General sweat, smelling slightly sour (first night), 25.
Very easy, profuse sweat, in spite of thin clothing, 11.
Very profuse sweats, of a very sour odor (after eleven hours), 83.
Skin covered with clammy sweat and blue spots, especially along the spine, 84.
Sour-smelling sweat, 14.
Sweating easily on walking, 10. [1180.]
Slight perspiration the whole night, 11 ; (first night), 10.
Transpiration of the skin was constantly increased by Colchicum; it frequently amounted to profuse sweat, 22.
Skin moist, clammy, cold as in cholera, 80.
Suppressed transpiration, 51.
Skin dry, hot, leaden-colored, 20.
Skin dry, body hot, 19.
Forehead covered with clammy sweat, 19.
Face covered with sweat (after six weeks), 20.

CONDITIONS

Aggravation.
( Morning ), Confusion in the head; after rising, especially on shaking head, feeling in head; on waking, pain in right forehead; tongue coated ; rawness in throat, etc.; on waking, nausea, etc., pain in stomach; on waking, pressure in upper abdomen; diarrhœa-like stool; in bed, burning in urethra; in bed, stitches in left chest; on waking, palpitation; on waking, drawing in small of back; bruised feeling in small of back; weakness of limbs; limbs feel weary; drawing in muscles of shoulders, eyes; weakness; on waking, weariness; on rising, weariness.
( Forenoon ), Eructations.
( Afternoon ), Frontal headache; towards evening, headache from forehead towards occiput; hunger; thirst; urging to stool; slimy stool; pressure in præcordial region; palpitation; pressure in sacrum, especially immediately after dinner; sensation in whole body; sleepiness; chilliness ; after dinner, coldness; cold feet; flushes of heat.
( Evening ), Headache ; headache in temple; pressure in temple; epistaxis; great appetite; while walking, pain in stomach; stitches in spleen; pain in abdomen; after eating, feeling in chest; in bed, drawing in thigh; in bed, tearing in middle of thigh; in bed, knee-joint painful; in bed, pain above knee; pain in whole body; griping, etc.; in toes; pains become intolerable; sensation of coldness.
( Night ), From beginning of night to break of day, all the varieties of pain; delirium; great flow of thoughts; colic, etc.; about 10 o'clock, pains in left chest; while lying on left side, fulness, etc., in heart; audible palpitation; pain in sacrum; uneasiness in all limbs; on moving about, pain in hip-bone; tearing in region of hip; towards morning, lascivious dreams; chilliness, etc.; heat of body; dry heat; sweat.
( After midnight ), After waking, slight sweat.
( Open air ), Lachrymation.
( Bending forward ), Heaviness in occiput.
( Bending head backward ), Headache in occiput.
( On blowing nose ), Pain in left chest.
( Coffee ), Aggravation.
( During dinner ), Nausea.
( After dinner ), Nausea; irritation in lower abdomen; pasty stool; yawning, etc.
( After eating ), Headache above eye; nausea; fulness in abdomen; sexual desire.
( Erect position ), Nausea; crawling in stomach.
( Lying quiet ), Backache.
( Mental exertion ), Symptoms very greatly aggravated.
( Motion ), Heaviness in occiput; pain over eye; vomiting; drawing in small of back; especially on flexion of hand, pain in metacarpus.
( Pressure ), Pain in region of spleen; sensation in upper abdomen.
( Raising eyes ), Headache in occiput.
( On rising ), Vertigo.
( Rising up in bed ), The symptoms.
( On going into room after walking in open air ), Pain in head.
( While sitting ), Sensation of warmth, etc.
( Sitting a long time ), Pain in scapula.
( Sitting still ), Throbbing in cervical arteries.
( While sitting after walking ), Vertigo.
( On going to sleep ), Palpitation of heart.
( Standing ), Nausea, etc.; pain at union of last vertebræ with sacrum.
( On going up steps ), Knee feels broken.
( After stool ), Faintness; weariness, etc.
( Walking ), Fulness, etc., in epigastric region; oppression of chest; pain at union of last vertebræ with sacrum.
( During long walk ), Sensation in bend of knee.
( Walking in wind ), Confusion of forehead.
( Work ), Especially reading or writing, very much affected.
Amelioration.
( Night ), Sensation in upper arm.
( Open air ), General relief; headache above eyes.
( Cold ), Pain in frontal eminence.
( Eructation ), Sensation in abdomen; colic.
( Motion ), Backache; especially in open air, sensation in whole body.
( Pressure ), Pain in frontal eminence.
( Rest ), Sensation in upper abdomen.
( Rest in bed ), Pain in forehead; headache in temple; chilliness.
( In room ), Confusion of forehead.
( Rubbing with hand ), Sensation in abdomen.
( Sleep ), Headache.
( Vomiting ), Nausea.
( Walking around ), Pressure, etc., in præcordial region.
( Warmth ), Pain in forehead.

SUPPLEMENT: COLCHICUM. Authorities.

86 , J. Y. Clark, M.D., Am. Med. Rec., vol. i, 1818, p. 369, John R. Peckworth took 100 drops of tincture; 87 , ibid., the author took 100 drops; 88 , Thos. Kennard, M.D., Am. J. of M. S., 1857 (1), p. 69, a woman, æt. fifty-six years, took one ounce of Colch. wine in twelve hours; 89 , Dr. Fifield, Bost. Med. and Surg. Journ., vol. lvi, 1857, p. 78, a man, æt. twenty-eight years, suffering from rheumatism, took half an ounce of Colch. wine; 90 , W. A. Hammond, M.D., Am. Med. Monthly, Feb., 1861, p. 83, took 1 fluid drachm at 8 A.M., 2 and 10 P.M. (first day); 1 1/2 fluid drachms three times (second and third days); 1/2 drachm (fourth day); 1 1/2 drachms (fifth day); 91 , ibid., a man, æt. twenty-three years, took 1 drachm tincture three times (first day); 1 1/2 drachms three times (second day); 92 , John H. Garner, M.D., Canada Lancet, vol. iii, 1871, p. 307, R. H. drank about a pint of tincture; 93 , ibid., J. M. J. took same quantity; 94 , ibid. T. H. took a small quantity; 95 , W. E. Porter, Med. Times and Gaz., 1874 (2), 723, poisoning of two children, æt. four and two years; 96 , Canada Pharm. Journ. (Pacif. M. and S. Journ., April, 1874, p. 572), a party of seventeen persons drank from one or two ounces to a pint each, of the wine, seven died; 97 , J. Pierre, Comptes Rendus, vol. lxxix, p. 633 (Pharm. Journ. and Trans., Oct., 1864, p. 325), the author plucked some fully expanded flowers, afterwards extended his hand over a large clump of flowers, carefully avoiding all contact, with the same result.

MIND

Muttered and raved wildly at times, but it only lasted a few minutes, 93.
Comatose, 92.

HEAD. [1190.]

Intense headache, 92.

EYE

Eyes red and watery, and the pupils dilated, 92.

EAR

Much tinnitus aurium, 92.

FACE

Expression of countenance anxious and haggard, 92.
Hectic flush occasionally on cheek-bones, 92.

MOUTH

Tongue dry and brown in the centre, and red along the edges, 92.

STOMACH

Great thirst, 92, 95.
Nausea, 94.
Sickness, 95.
Vomiting in from three-fourths of an hour to an hour and a half, 96. [1200.]
The ejecta were bilious, and then of the rice-water character, 96.

ABDOMEN

Extreme tenderness over abdomen, and the intermittent severe pains precisely similar to peritonitis, 92.
Tormina, 95.

RECTUM AND ANUS

Tenesmus, 95.

STOOL

Purging, 96.
Severe diarrhœa (second day), 91.
Purged and vomited violently, 92.
Purging in from three-fourths of an hour to an hour and a half, when a large quantity was taken; later when the quantity was small, 96.

URINARY ORGANS

In three days immediately preceding commencement of experiment, the average quantity of urine for each day was 1425 cubic cent. of sp. gr. 1021.73. The average amount of solid matter was 64.28 grams; of which 30.18 were inorganic, and 34.10 organic substance. The average amount of uric acid excreted for each period of twenty-four hours was 0.77 grams. Quantity of urine excreted 1685 cubic cent., sp. gr. 1021.5; total amount of solids 70.15 grams, of which 30.90 were inorganic, and 39.25 organic matter; quantity of uric acid 0.81 gram (first day). Quantity of urine 1720 cc., sp. gr. 1020.87; total solids 75.29 grams; inorganic solids 32.44 grams; organic solids 42.85 grams; uric acid 0.69 grams (second day). Quantity of urine 1784 cc.; sp. gr. 1022.57; total solids 80.13 grams; inorganic salts 35.11 grams; organic solids 45.03 grams; uric acid 0.82 gram (third day). Quantity of urine 1540 c.c.; sp. gr. 1023.17; total solids 69.23 grams; inorganic solids 31.09; organic solids 38.14; uric acid 0.78 gram (fourth day). Quantity of urine 1698 cc.; sp. gr. 1023.68; total solids 76.14 grams; inorganic solids 32.36 grams; organic solids 42.88 grams; uric acid 0.76 gram (fifth day), 90.
Average daily quantity of urine 989 cc.; sp. gr. 1020.14; total solids 51.20 grams; inorganic solids 22.45 grams; organic solids 28.75 grams; uric acid 0.47 gram (before experiment); quantity of urine 1021 cc.; sp. gr. 1024.18; total solids 63.25 grams. inorganic solids 23.57 grams; organic solids 40.68 grams; uric acid 0.59 gram (first day); quantity of urine 8875 cc.; sp. gr. 1026.11; total solids 60.25 grams; inorganic solids 20.38 grams; organic solids 39.87 grams; uric acid 0.51 gram (second day), 91.

RESPIRATORY ORGANS. [1210.]

Coughed severely at regular intervals, 92.
Blood in sputa, 92.
Breathing rapid; heavy, almost stertorous (after a few hours), 92.

CHEST

Great fulness of the chest, 92.

PULSE

Pulse 80 (before experiment); 78 (in five and ten minutes); 76 (in fifteen and twenty minutes); 78 (in twenty-five and thirty minutes); 80 (in thirty-five, forty, and forty-five minutes); 78 (in fifty minutes); 76 (in fifty-five minutes); 72 (in sixty minutes); 70 (in sixty-five minutes); 68 (in seventy and seventy-five minutes); 72 (in eighty and ninety-five minutes); 70 (in one hundred minutes); 72 (in one hundred and five, one hundred and ten, and one hundred and fifteen minutes); 76 (in one hundred and twenty minutes); 80 (in one hundred and eighty and two hundred and forty minutes), 86.
In five minutes after taking the medicine, his pulse became considerably reduced, both in force and frequency; in thirty-five minutes he had a copious discharge of pale-colored urine, his pulse much increased; in fifty minutes, very sleepy, pulse again reduced; in seventy minutes, his mental faculties became much exhilarated, pulse very slow and soft; in ninety minutes, perfectly free from any peculiar feelings, pulse somewhat increased; in one hundred and eighty minutes, pulse very natural, 86.
Pulse 70 (before experiment); 52 (in five minutes); 48 (in ten minutes); 46 (in fifteen minutes); 42 (in twenty and twenty-five minutes); 48 (in thirty minutes); 43 (in thirty-five minutes); 45 (in forty and forty-five minutes); 39 (in fifty minutes); 43 (in fifty-five minutes); 46 (in sixty minutes); 50 (in sixty-five, seventy, and seventy-five minutes); 45 (in eighty, eighty-five, and ninety minutes); 47 (in ninety-five minutes); 50 (in one hundred, one hundred and five, one hundred and ten, one hundred and fifteen, one hundred and twenty, and one hundred and twenty-five minutes); 53 (in one hundred and thirty minutes); 55 (in one hundred and thirty-five minutes); 57 (in one hundred and forty minutes); 60 (in one hundred and forty-five, one hundred and fifty, one hundred and fifty-five, one hundred and sixty, and one hundred and sixty-five minutes); 65 (in two hundred minutes); 70 (in two hundred and seventy-five and three hundred minutes), 87.
In five minutes after taking the medicine my pulse became diminished, both in force and frequency; in fifteen minutes I felt considerable flushes of heat passing over my face, and followed by a considerable degree of vertigo; in fifty minutes, my pulse became still more diminished; in sixty-five minutes, I was somewhat sleepy; and in seventy-five minutes, I was very sleepy, attended with a slight diaphoresis; in one hundred and thirty minutes, my pulse began to increase in frequency, but continued diminished in force; and in two hundred and thirty-five minutes, was natural, both as to force and frequency, 57.
Pulse 160; grew feeble (after a few hours), 92.

SUPERIOR EXTREMITIES

Numbness in the arms, 97. [1220.]
In a few seconds his fingers changed color, and took the livid greenish tint characteristic of a corpse in a state of incipient decomposition. After about ten seconds the skin regained its color, 97.
Cramps of the fingers, 96.

GENERALITIES

Convulsions, 95.
Extreme prostration, suffering from excessive nausea and vomiting, with slight purging, heat and burning in the fauces, inordinate thirst, cold, clammy skin, feeble pulse, violent supra orbital pain, and distressing gastralgia, with very anxious countenance, 88.
Pale, cold, vomiting constantly, purging, and complaining of great thirst and pain at the epigastrium, 89.
The symptoms were mainly those of violent cholera morbus, 96.
Debility, 94.
Very much exhausted, 92.
Similar symptoms, but milder, except the headache, which he described as most intense, 93.

SLEEP

Insomnia, 96.

FEVER. [1230.]

Shivering, 95.
Coldness, 95.
Whole body clammy and cold, 92.
Feet and hands cold, 92.
Cold sweat on forehead, 92.

MIND

HEAD

EYE

EAR

NOSE

FACE

MOUTH

THROAT

STOMACH

ABDOMEN

RECTUM AND ANUS

STOOL

URINARY ORGANS

SEXUAL ORGANS

RESPIRATORY ORGANS

CHEST

HEART AND PULSE

NECK AND BACK

EXTREMITIES IN GENERAL

SUPERIOR EXTREMITIES

INFERIOR EXTREMITIES

GENERAL SYMPTOMS

SKIN

SLEEP AND DREAMS

FEVER

CONDITIONS

MIND

HEAD. [1190.]

EYE

EAR

FACE

MOUTH

STOMACH

ABDOMEN

RECTUM AND ANUS

STOOL

URINARY ORGANS

RESPIRATORY ORGANS. [1210.]

CHEST

PULSE

SUPERIOR EXTREMITIES

GENERALITIES

SLEEP

FEVER. [1230.]

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