Nuphar luteum
di Richard Hughes & Jabez P. Dake — A Cyclopaedia of Drug Pathogenesy
Volume IV — Appendix
NUPHAR.
Nupkar bUtum, Smith. Small-flowered yellow pond lily, Nat. Ord., Nymphdcacex,
I. Prwingi. — 1. a. Dr. Pitet took 4lh dil. irregularly for several d. On 6ih
d. he had some colic, and Frequent prickings on post, surface of 1. thigh. On 9th
^jmd 10th d., pressive headache in forehead and I. temple. On nth there was txcrs-
^Kve moral sensibility, causing great pain on witnessing sufferings of animals ; head-
^^■hc in forehead, and at times in 1. temple, ceasing in open air. There was diminu.
^Hon of sexual thinking and feeling during 10 d., opposite effect occurring during
^^ccecding 4 d. After 10— i a d. there appeared on different parts of body a number
^of red blotches, tolerably regular in outline, ovoid or circular, prominent, and covered
with Utile scales of silvery while— in short, resembling psoriasis. There were a few
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6s8
on post, jurface of artnii, but they were most numerous on ant. surface of legi; (hty itched violently, especially in e. ; friction removed the little »ca]e^, \Thich wtrenpidlj reproduced, remained a few day^ and then fell off again from the scratching muuctd by the itching. This eruption lasted six weeks; as it disappeared, and theioln ceased to be reproduced, skin at seat of each blotch became pale red or ycllowisl).
b. Subsequently, Dr. P. took frequent doses of 4th and 6th diU. — 4tn d.,»wKtiJ) taste several times. 7th d., boring pain, in transitory attacks, in 1. forchud, e. 8th d., soft stools, preceded by some colic, for several d. ; complete absence of sexual desire, penis retracted, scrotum relaxed ; lancinations in r. great toe, c. 9th d.,paioful sensation behind sternum, when running, as though subjacent organs wer« tiolently shaken. lolh d., heaviness of whole head, at midday ; dull or tearing pa>U* sometimes in forehead, at others in whole upper half of head ; dull deep lancicaiioe^behind I. frontal eminence; face pale, discoloured eyes, though not feeling ill; stiU entire sexual insensibility and atony ; constant restlessness and fatigue in legs; piinlul drawings in ant. muscles of 1, leg j great impatience at slightest contndiciioo ■ iith d., very painful bruising shaking pain in brain at every step in walking; •''•'^ pains in 1. ant. cerebral lobe, and occasionally beneath orbital plate, taih d., paintisi bruising shocks in r. brain anteriorly when walking. 1 5th d., diarrhceic stools S3« and e., preceded by violent colic pains in rectum. x6th d., same all n. 171b d-
4 diarrhceic stools, smarting and oumiag in anus after each; in e. some fUtuks^i colic; urine deposits a reddish sand, which is hard and adheres to vessel, ilihildull deep colic pains during d., all round waist ; 4 diarrhceic stools as before; co^' tinued sexual depression. 19th d., 4 similar stools, two 4 — 5 a.m.; slight painhtl' ncss over whole ant. surface of stomach, with senw of weakness at epigiitriuink lancinations in r, testicle; general sense of weakness. loth d,, diarrhceic stool i^f in. ; some pain in r. testicle, ajrd d., dull pain and sense of painful weight int. orl>« all d., and since m, also in r, ant. cerebral lobe and occiput ; (when standing in nia, ' quantity of brilliant sparks filled field of vision, converging froni tircMmfcrcDct C centre), — this was frequently perceived subsequently, principally after hard coughing^ (paroxysms of very acute but transitory pain in r. great foe, when walking), tft" d., dull pains, sometimes lancinating, about r. ant. cerebral lobe ; painful heavines i* orbit, at base of skull, — a very frequent symptom since beginning of proving. 9* the a9th d., strength, flesh and healthy complexion, which had diminished, bega^ to return.
r. Same proved 6th, 7th, and gth dils. during la d. — Sth d., deep dull pa>D * lowest part of 1, lumbar region and in post, sup. part of cxt. iliac loss*, coiocidia with a similar but not constant pain in internal iliac fossa of same side; >eD>a/tiu0^ like f!eabites, in different parts, for several d. 9th d., lancinations in I, anterior loth d,,saine, and similar but less violent sensations on other side ; painful in r. temple, nth d., diminution of erections and sexual appetite; walLinig, slowly, causes painful stitch in 1. flank, relieved by pressure ; weakness of limb? e. ; yellow diarrhoea, especially in m., had occurred for 3 d. past; to-day then
5 or 6 stools, without colic or epigastric trouble, except at times a sense of weal there. On following days all symptoms of nth d. continued, stools being more numerous about 5—6 a.m. 101 h and following day», dull pains in axiterror of base of brain, on level with floor of orbits ; very painful feeling of weigl temples, m. ; stitches, as from needles, in rectum, above anus ; sensation like bites on different parts of skin of body and limbs. 35th d., dull pains at has; «'' orbit, forehead, and occiput ; soft diarrhceic stool, preceded by colic, " ' appeared after the stool ; dull transitory pain in r. testicle, for several d. in <u< similar pain at extremity of penis, r. side, several lancinations in I. testicle thctr On 20th and follo»ing days, a red, slightly prominent patch, covered niib white scales, and itching violently, on inner surface of r. arm, near a>"! on 25th (1. by a red, oval, prominent patch on I. arm, exactly like a p.-i: covered with silvery scales, which fall off and are renewed every iew ii., ■'•■ violently, especially in e.* (Joura. de la Sec. Gail,, iii, 119.)
• With reference to these cutaneous symptoms. Dr. Pitei thinks it rigit •" mention that he is of scrofulous constitution; and that though he had never hid ".' eruptions previously 10 his proving N., four years later he sufTertd from jjnic^ psoriasis, and every year since then two or three patches of it have appeared. — Ef-