Cyclamen europaeum

Volume II — Main text

CYCLAMΕΝ . Cyclamen europaum, L. Sowbread. Nat. Ord., Primulacee. I. Provings.-1 . HAHNEMANN, Mat. Med. Pura, vol. v of original, vol. i of translation. Contains 5 symptoms from self, and 197 from 4 fellow- observers . 2. D-, medical student, æt. 22, January 27th, 7.50 p.m., 4 dr. tinct. Confusion in 1. side of forehead, gradually spreading all over head, prickling in scalp, going off in a few m., then slight pains in abdomen, frequent eructations tasting of the drug, with acrid taste in pharynx ; drawing pains in flexor muscles of both legs, from hough to tips of toes ; upper extremities heavy; pressure in canthus of 1. eye ; jerking and drawing pain from 1. temple to crown, with confusion of head, especially in forehead, and stiff feeling in nape ; urging to urinate and pressure in anus ; stitches in apex of heart; tearing in 1. maxillary joint and in l. forearm ; rumbling and pinching in abdomen ; sneezing. At n. frequent erections without exciting dreams ; frequent waking with pressure on eyelids and stitches in heart ; slept long in m.; urine much diminished.-28th, 6.22 a.m., 6 dr. Immediately throbbing in upper part of abdomen ; saliva diminished, spits yellowish-white, consistent lumps the size of lentils or beans (this always occurred, for 5 or 6 d.) ; no appetite for breakfast ; after breakfast rumbling,then pains in abdomen, urging to stool; pressure in eyelids as if they stuck together ; confusion of sinciput and itching of scalp; stool forcibly ejected, first lumpy, then soft, with palpitation of heart ; heat in head and belly ; stools inodorous, brownish-yellow, mixed with mucus ; cross without cause ; vertigo ; pressure in stomach, pulse and respiration quickened ; pulse strong, gradually getting calmer ; violent sneezing ; itching in ear, much ear-wax; contractive pain and empty feeling in temporal region ; great internal heat ; frequent sneezing and yawning ; jerkingshooting pains in r. temple, gradually spreading to face, worse when moving ; pulse scarcely perceptible and very quick, as also respiration ; itching in eyelids and elbow ; weak voice when reading ; hiccup ; shooting in urethra and urging to urinate; urine dark reddish-yellow ; drawing pain in hough when standing; scraping and dry feeling in trachea in open air, causing suffocative cough ; light-coloured urine ; expectoration of mucus ; dryness of nose; feeling ofemptiness in head passing into prickling on scalp and skin of face ; a lump the size of a lentil above parotid with painful itching ; itching on scalp, neck, * "A dog was made to swallow 4 ctgrm. of a concentrated solution while fasting. After 3 h. it fell, and gradually lost sensibility ; respiratory movements became feeble, and then ceased ; cornea lost its sensibility ; and heart, which stillcontinued to beat very well, and some slight convulsive movements, alone showed that life was not extinct " (CL. BERNARD, Leçons sur les subst, tox., p. 338) .

shoulders and axillæ ; drawing pain in r. hough changing into formication ; tearing in left leg ; shooting in urethra ; dislocation pain in shoulder-joint ; heat and full feeling in r. side of head ; twitching, cutting pain along inguinal canal ; tearing, shooting, jerking in two of the front r. upper molars ; chilliness in open air ; much urine coming away in a large stream ; hiccup ; great appetite. 8.40 p.m., 8 dr. Constrictive painin throat from smell ofdrug ; pressive pain over nasal bones ; eructation ; severe palpitation ; some stitches in r. side of chest above 6th rib ; tearing pain on outer side of r. thigh ; veins of back of hand swollen ; sore sensation on glans penis and prepuce ; pressure in middle of sternum ; shooting in both sides ofhead, worst in coronal suture ; shooting inhepatic region, 1. inguinal canal and anus ; sneezing ; pain from bladder to urethra when urinating ; frightful dreams ; dryness and painfulness ofthroat.-29th, 5.26 a.m., 10 dr. Frequent expectoration of above-described substance ; itching in l. inguinal canal ; beats of heart and pulse scarcely perceptible ; stool like yesterday; dislocation pain in 1. foot ; pulse dicrotic, very quick ; respiration very quiet ; fluttering in 1. side of chest; pains in stomach and abdomen ; heart's beats slower ; contraction of eyelids as from intense light ; frequent yawning; giddy fulness and heat in head ; sore pain in both heels hindering walking; loss of smelling power ; great thirst when eating dinner ; great hunger; restless sleep; itching in lower jaw ; papular eruption on scalp, face, and other parts of skin ; much hawking ; yawning ; renewed straining after stool.-31st, 4.50 p.m., 2 drachms Ist dil. Stitches in 1. side ofchest increased by inspiration. Confusion in forehead and itching of scalp. Numb feeling in r. hand ; some stitches in stomach ; squeezing together ofjaws ; sore pain in r. upper incisors, especially in their crowns and thence over buccal lining ; drawing pain in r. knee-joint, in acromion and hough ; pressure in stomach ending in eructation ; pulse nearly imperceptible ; some coughing ; joints painful on movement ; itching under shoulders ; excited action of heart ; vibration in cardiacregion; yawning ; eyelids seem contracted.- Feb. 1st, 9 a.m., some dr. of Ist dil. introduced into eye. Immediately pupils contracted but soon dilated, the vessels of iris could be seen ; contraction and dilatation alternated every second, and connected with respiration in this way, that they occur only after each in- or ex-piration. This phenomenon lasts h. in diminishing degree. 9.45, the drops again instilled ; great contraction of pupil followed in 3 or 4 seconds by dilatation and so on, till at last great contraction of pupils remains ; many pimples appear on face, which fill with yellowish-white lymph, and then shrivel up. The cicatrices of former varicella reappear, of a dark red colour; the forehead thickly studded with similarly coloured spots the size of lentils ; uvula and tonsils very contracted and white ; eructation ; pulse scarcely perceptible ; confusion of forehead ; dislocation pain in 1. hough. 2 p.m., 3ss of Ist dil., eructation ; confusion of head ; bowels painful to touch ; some pain in abdomen ; pressive pain in forehead ; abdominal pain increased ; yawning ; blood-vessels visible in white of l. eye ; tinnitus aurium; contraction offrontal muscles as if angry ; weakness of memory ; out of spirits ; distension of abdomen with flatulence ; vision sharper, can distinguish colours at agreat dis

tance ; pressive pain in pit of stomach ; painfulness of abdomen on pressure ; stitches in umbilical region ; buccal and faucial cavity redder ; quivering of r. upper eyelid; sharp stitches in coronal suture ; urine dark coloured and many flakes in it ; the pains in belly persist ; itching in r. inner canthus ; whole head confused ; noise in ears.-2nd, 12.30 p.m., 3j of 1st dil. Pressive pain in 1. temple; heat in head ; confusion ofr. side ofhead ; eructation with greasy odour ; exhaustion ; quivering of eyelids ; chilliness, then after crossness attacks of heat and throbbing in head ; nearly complete loss of appetite and thirst ; pressive-tearing pain in r. upper jaw and crown of r. canine tooth ; much expectoration ; pupils very contracted ; tongue covered with yellowish-white fur; shooting in coronal suture and pulsation of temporal arteries ; itching in hairy scalp; stool delayed 9 h.; pain in r. lower row of teeth; constriction in throat ; shooting in stomach ; tearing pains in elbows and wrists ; quivering in eyelids when pressed or rubbed ; many pimples on jaw, rapidly filling with white lymph ; stool of hard lumps, thereafter confusion of head, great forgetfulness, makes mistakes in words ; pressure on sternum ; pressive-tearing pain in l. upper row of teeth; starting out ofsleep ; liquid stool; boring pain firstin r. metatarsal bones and r. temple, thence into r. upper row of teeth, then in 1. temple; burning in r. eye ; thirst after 5 d. absence of thirst ; retracted prepuce in open air.-4th, 4 p.m., 3j of 4th dil.-5th, m. , stool at first normal, then quite liquid, of light yellow colour ; urine light coloured, containing many epithelial cells. 9 a.m., shooting in 1. temple, then in whole sinciput with vertigo ; later, pressure in forehead, yawning. 11.44 a.m., zij, eructation . 3 p.m., drawing pain in 1. hough.-8th . After inhaling vapour of tinct. 2 p.m. , pressive, stupefying, frontal pain.-9th, 3 p.m., transient sore pain in 1. acromion, especially when taking off coat.- 10th. Pressure in l. inner canthus ; pressive stupefying pain in r. side of sinciput, then nausea and eructation ; retraction of prepuce ; much sediment in urine, which is acid and contains much chloride.- 11th. Slimy stool, which passes unobserved.- 15th and 16th. From inhaling vapour of tinct., pressure, later shooting in r. coronal suture, with general confusion of head ; quivering of r. upper eyelid every 4 or 5 m., also when he rubs eyes or forehead ; this symptom lasted several d. In face and forehead reddish spots and some large pustules ; pulse ranged during proving from 60 to 108, resp. from 6 to 19 (normal resp. 15). (HAMPE, Zeitsch. des Vereins d. hom. Aerzte Oesterr., 1857, ii, 445.) 3. Dr. EIDHERR, æt. 29, took on Oct. 21st, 5, 22nd, 7, 23rd, 9, 24th, 11 , 25th, 13, 26th, 15, 27th, 20 dr. About 2 h. after taking drug there always occurred slight headache lasting some h., and after the 2 last doses also nausea and inclination to vomit ; no other symptoms. (Ibid, 444.) 4. A girl, æt. 17, regularly menstruated since æt. 15. Oct. 27th, 6 p.m., 5 dr. 1st dil. 8 p.m., felt very unwell, vertigo for 5 m., objects seemed to go round in a circle, must go to bed ; repeated eructation, then fell quietly asleep, and woke next m. quite well.-28th. 6 dr. 8.30 p.m., felt anxious, head felt bound up, objects seemed to have a swinging movement, all gone in 15 m. except confusion of head.

After several cold compresses on forehead, head became free and she could read. After 45 m. she had a sort of faint, all objects flew round her in a circle, darkness before eyes ; violent vomiting ended the scene. Next N. restless, frequent attacks of anxiety and nausea disturbed rest. d. exhausted, face pale, eyes sunken, pulse 108, appetite gone, great thirst. Next n. the menses, that had only stopped 14 d., returned.- 30th. Gastric symptoms, such as very furred tongue, frequent eructation, very distended stomach and inclination to vomit. Could only take lemonade, everything else made her sick.-31st. Menses stopped, same symptoms, but slighter.-Nov. 4th. Quite well.-7th. Menses returned, and ran regular course. (Ibid., 455.) 5. A girl, æt. 17, of melancholy temperament, but in good health, took on Oct. 27th 5 dr. 1st dil.; no effect.-28th. 6 dr., after 2 h . slight confusion of head that soon passed off.-29th . Io dr. , same as yesterday.- 30th. 15 dr., deep sleep, with confused, fright-inspiring dreams. Next d. more melancholy than ever, complained of feeling like to weep and of heaviness in feet.-31st. 20 dr., menses came on 4 d. too soon, with relief to above symptoms. E., observed a ring round candle, on account of which she had to leave off her sewing several times . Nov. Ist. 25 dr., slight confusion of head and dimness of vision, so that she could not work ; could not see distinctly the outline of fingers held before her. Menses ceased.- 2nd. No med.; a little flickering before eyes. 4 p.m., menses again came on, and ran a regular course. At n. some griping in belly. Till 9th without med. E., 5 dr. tinct. Slight flickering before eyes and confusion of head. Went on increasing dose by 2 dr. every d. till she took 15 dr. Confusion of head and dimness of vision always ensued.-29th. Menses came on and were regular and painless. (Ibid., 456.) 6. A girl, æt. 16, had menstruated 14 times. In June took a cold bath. Menses came on immediately afterwards, but ceased same n ., and had not since reappeared. Of late had been lethargic and cross. -Oct. 23rd. 5 dr. 1st dil .; after 4 h. confusion of head and noise in ears.-24th. 8 dr., after 2 h. severe headache and transient nausea. Restless at n.-28th . 10 dr. , after 2 h. headache which lasted till e. , constant nausea. Restless n.- 26th . 12 dr. , after 2 h. severe headache ; after 3 h. vomiting, followed by great confusion of head. Sleepless at n. and pressing down in abdomen.-27th. No med. In the n. menses came on, with great pain in abdomen, went on for 6 d. without more pain. Menses again occurred on Nov. 23rd, and were quite normal . ( Ibid., 457.) 7. Dr. v. KACSKOWSKI, Oct. 22nd, 9.30 a.m. , I dr. tinct. Burning in throat immediately. After dinner frequent micturition, increased heat of head, much flatulence. Fell asleep before 10 p.m. as if from fatigue, confused dreams.-23rd. Looks more tired than when he went to bed ; stool with much straining. 9.30 a.m., 20 dr. Burning in œsophagus, frequent discharge of flatus upwards and downwards ; frequent discharge of watery urine. After dinner great exhaustion, cold feeling all over ; confusion and heat of head ; flow of saliva. After 10 p.m. profound sleep with confused dreams.-24th. Woke tired, depressed ; sudden call to stool, which was liquid, and attended with

burning and straining, some blood passed; head hot, confused; taste flat, cold feeling in body, frequent micturition, with pains in bladder and rectum ; frequent discharge of wind upwards and downwards. 10 a.m., 3 dr. Immediately burning in œsophagus for 15 m.; watery mouth, with pasty taste ; flatus and frequent micturition continued. After dinner cold feeling in body, head warm and confused. E., great exhaustion, profound sleep and confused dreams.-25th. Woke tired, cross, confusion of head, pasty taste ; after breakfast, frequent micturition, with pressure in stomach ; consistent stool, with burning in rectum. 10 a.m., 4 dr. After dinner general coldness and congestion of brain ; exhaustion, crossness, discharge of wind upwards and downwards, frequent micturition with straining. E., exhaustion, sleep restless, confused dreams .-26th. Woke tired, with sticky mouth and excited humour ; frequent eructation, with disagreeable feeling in stomach. 10 a.m., 5 dr. Burning in cœsophagus and secretion of saliva and mucus in mouth ; eructation, with pressure in stomach increased ; no stool ; much flatus ; head hot. After dinner general coldness and congestion of head. Towards e. hot head, distension of abdomen ; later, discharge of flatus ; cold feeling continued. At 10 p.m. took tea with a tablespoonful of rum, the body became warm. At 11.30 deep sleep, with lascivious dreams.- 27th . Woke tired, cross, with pasty taste. After breakfast confusion of head, watery mouth, eructation and pressure in stomach. 9.30 a.m.,6 dr. Immediatelyburning in cœsophagus for h., much saliva and mucus in mouth, eructation with disagreeable feeling in stomach. After siesta crossness, tension in abdomen, discharge of wind up and down, great flow of urine, with pressing on bladder and rectum, heat of head and chilliness over back. E., exhaustion and prostration ; confused dreams.- 28th. On waking, great laziness, mouth pasty, head hot, pressure in stomach, wind up and down. 10 a.m. , 7 dr. Burning in œsophagus for h ; much saliva and mucus in mouth, with frequent hawking,tension in hypochondria, eructations, heat of head, stretching of limbs as before a febrile attack. After siesta coldness over back, great heat in head and eyes, frequent urging to urinate, with pressure on rectum. E., great exhaustion ; n., many dreams.-29th, 10a.m., same symptoms, and in addition tension in inguinal region.-30th. Woke with usual symptoms and pressure in temples. I p.m., 9 dr. Same symptoms.-Oct. 31st. Usual m. symptoms. II a.m. , 10 dr. Usual symptoms, and in addition swelling of hæmorrhoidal vessels.-Nov. 1st. More tired on waking than when went to bed, flow of saliva, head hot, pressure in forehead,tight feeling in chest, tension in hypochondrium, pressure on bladder and rectum. 10 a.m., II dr. Burning in cœsophagus for h., tension in hypochondria. After dinner coldness over back, pressure on bladder, heat in rectum, with swelling in hæmorrhoidal vessels.-2nd, m., exhausted, cross. 9 a.m., 10 dr. The same symptoms repeated. (Ibid., 458.) 8. Dr. W. Löw, Oct. 22nd to 27th, took daily 4 dr. of tinct. The first 4 d. no effect.-26th. Feeling as if objects turned round in a circle. 27th. Vertigo repeated and more persistent,worse when walking in open, better when sitting in room.-28th. 8 dr., intoxicated con VOL. II . 32

fusion and heaviness of head, transient.- 29th. 12 dr., soon general discomfort, no appetite for breakfast, which was followed by nausea and vomiting. All d. felt unwell, periodical vertigo, loss of appetite, and fulness of stomach. After a very restless n., often waking up with a start from disagreeable dreams, woke on 30th exhausted and dejected. All d. no appetite ; after a cup of coffee in e. inclination to vomit and belching up of acidity. To-day and yesterday distaste for beer, which he usually relished. Discontinued medicine. The discomfort, heat in face, andcoldness ofextremities lasted till midnight, and caused restless sleep. After midnight feeling ofgreat comfort, slept profoundly, awoke late refreshed and well.-31st. Only constipation and scanty urine.- Nov. Ist. 12 dr., the former symptoms recurred, vertigo andderangement of digestion, and stool with violent tenesmus, and discharge of drops of blood ; also slight epistaxis. (Ibid., 462.) 9. K. MAYRHOFER took from Oct. 13th to 31st increasing doses every d., from 2 to 32 dr.-Nov. 3rd, 9 p.m., 40 dr. Left off on account of some diarrhea.-Dec. 6th to 10th daily from 44 to 56 dr. -10th. On r. side of chest a spot of eczema 1 inch by 4 lines.- 1 Ith, 8.30 p.m., a sudden violent rigor, went to bed, but had a sleepless n. , with febrile heat. Next d. felt very unwell, forenoon moderate fever with headache, lasting till afternoon. A more intense fever in e.,lasting till 2 a.m. (Ibid., 463.) 10. Dr. S. SCHWARZ, æt. 23, is subject to attacks of a peculiar headache in front of head, otherwise well.-Oct. 22nd. 6 dr. tinct, m. and e., no symptoms.-23rd, m. and e., 6 dr.-24th. 10 dr. , nothing observed but scraping feeling in throat on swallowing dose.-26th, m ., 20 dr. After breakfast and after dinner eructations of wind. An attack of his usual headache, along with heaviness of head, and irrepressible yawning. Slept all through n., an unusual circumstance.-27th, m., 30 dr. Before and after breakfast, after griping in bowels, 2 diarrheic stools. Same symptoms as yesterday, only the headache was limited to 1. side, and was of a dazed and heavy character. Great yawning in e., tired and sleepy, went to bed at 8 p.m., but could not read as usual, on account of burning and flickering of eyes. Slept soundly for 12 h., never sleeps more than 7. The next 3 d. he increased the dose by 10 dr. daily, till he took 60 dr. on 30th, but had no new symptoms ; the former ones continued in the same intensity. Further trials of the 3rd dil. caused no new symptoms. The tired feeling, sleepiness and yawning lasted 14 d. after ceasing the proving. ( Ibid., 464.) 11. Dr. A. v. SZONTAGH, æt. 26. Began on Oct. 6th with 3 dr. tinct., increased the dose every d. by I dr. till 9th. Then increased every d. by 5 dr. Finally, on 20th, took 60, on 21st 70, on 22nd, 90 dr. The only symptoms he observed were burning scraping in cæsophagus for 1 h. after the dose, later passing into a feeling of swelling of palate ; increase of stools, 2 on some d., disturbed sleep, and noise in ears while walking after the last dose. (Ibid., 465.) 12. Dr. RUD. VIVENOT, æt. 23.-Nov. 22nd. 5 dr. tinct., immediately persistent scraping in œsophagus, and eructation with taste of drug.- 10 and 15 dr. on nextd. caused same effect.-26th 25 dr., 27th 30 dr., 28th 40 dr. In all these d. the scraping and eructation as before,

also confusion of head, pressure in temples, general prostration, weariness oflegs and drowsiness, withyawning. Throughout proving burning in eyes, especially when reading, injection of conjunctiva.- 29th. At n. awoke with violent pinching in umbilical region, relieved by kneading and removedby stool; full feeling and slight distension of abdomen remained. During d. 2 loose motions, frequent rumbling in bowels and flatus.-Dec. 4th 50 dr., 5th 60 dr. , 6th 80 dr.; precisely similar symptoms occurred.-7th., forenoon, 2 liquid stools, then took 100 dr., which caused diarrhea for 5 d. (Ibid., 466.) 13. A maidservant, æt. 35, menses had been delayed a week.- Dec. 4th, 6 dr., 5th, 8 dr. tinct., each time in a wineglassful of water, a teaspoonful every 2 h. The Ist. d., e., great confusion of head, vertigo as ifall objects were swaying around her, a stupid feeling in head, which was hot, eyes sparkling, alternation of heat and cold, pulse hard, more than 100, then nausea, rumbling and cutting in bowels followed by watery diarrhea. Long of falling asleep, many dreams, often woke suddenly, woke up completely at 4 a.m. and went to sleep at 6.30 a.m., great disinclination to rise in m. when she had violent coryza, which was most likelythe cause of the febrile symptoms. The secondd.the same symptoms continued. The diarrhoea continued. Shooting pain in r. forehead and temple for h., stitches in brain on stooping ; flickering before eyes, as from many-coloured glittering needles, vision as through smoke or mist ; eyes deeply sunk, surrounded with blue circles ; great weariness and prostration of whole body, paralytic heaviness offeet rendering walking difficult; felt as if everything would drop out of her hands ; cross and low-spirited, no inclination to work; anxiety as if some misfortune were about to happen. The following n. menses came on with violent labour-like pains, all d. abdomen so distended she could scarcely stoop ; the blood came away in large black clots, usually her menses were painless and the discharge bright red and fluid. Having gained her object, which was the restoration of menses, she would not continue the medicine, as she felt very poorly. After 8 d. she returned complaining that she was not right, thought she must be pregnant, as she had the same symptoms as during her former pregnancy 13 years previously. She had sour eructations, flow ofwater into mouth, sometimes great hunger, then again complete anorexia. Abdomen and stomach constantly swollen, felt in bowels under liver a ball-like swelling which could be distinctly felt by others ; also moving about there as if something alive were in it. The sensation extended to breasts with a feeling as wind streamed out of nipples ; the breasts felt enlarged and she had tension and stitches in them ; the breasts were in fact enlarged, hard, and painful ; milk exuded from nipples ; it was watery milk like what occurs in the first days after delivery ; it flowed out of itself and could also be pressed out. This continued off and on for 14 d. and the disagreeable feelings in the breasts went off. Examination did not show pregnancy, and as the symptoms continued though the drug had not been taken for 2 weeks she got pulsatilla, which soon made her quite well. Since then the menses have occurred regularly without any discomfort. (Ibid. , 468.)

14.* F-, a working girl, æt. 22, subject to palpitation of heart, regularly men. struated ; at present copious menses for 10 d..-Sept. 28th. 5 dr. tinct., vertigoas if going down a hill; sleep restless ; menses increased ; palpitation.-29th. 10dr., menses ceased; great palpitation ; exhaustion; restless sleep disturbed bydreams.- 30th. 15 dr., violent palpitation; burning in 1. side of chest; sees objects double; n. very restless as though big beasts were running over her body; constipation for 3 d. (before that had diarrhea), general exhaustion.-Oct. 1st. 16 dr., contraction in throat, constipation, sleeplessness, sweat at n.; trembling of hands and feet; great inclination to vomit, at last vomiting; dimness ofvision; vertigo and exhaustion.-2nd. 18 dr., great palpitation; went to bed and perspired profusely.- 3rd. 24 dr., constipation continues; less palpitation and vertigo; e. inclination to vomit.-4th. 30 dr., vertigo, constipation and exhaustion. (Ibid., 470.) 15. M. R-, a girl, æt, 17, menses regular, until last 6 m.,when they have remained suppressed. Sept. 28th. 5 dr. tinct., immediately vomiting, vertigo, later, weariness in legs ; sleeplessness.- 29th. 10 dr., after 6 h. vomiting; vertigo, exhaustion ; no sleep, great restlessness at n.- 30th. 3 dr., no symptoms.-Oct. 1st. 15 dr., frontal headache; sleeplessness part of n.,then restless sleep with disagreeable dreams.-2nd. 20dr., only frontal headache, less than yesterday. (Ibid., 471). 16. J. B-, a girl, æt. 17, in good health,menses regular, has them copiously at present.-Sept. 28th. 5dr. tinct., immediately vomited twice, then drowsy.-29th. 10dr., vomited twice watery slime, then became giddy, went to bed, had alternately heat and cold, after which profuse sweat, menses unaffected.-30th. 3 dr., must lie down on account of vertigo, restless sleep, often cried out; sees green and yellow before eyes.-Oct. 1st. 5 dr., immediately vomiting of a slimy mass ; this was followed by sleep which was restless and broken by starting up and disagreeable dreams; all objects seen double; heat of head; e., rigor followed by sweat. Exhaustion and prostration. The proving had to be interrupted as she had an attack of erysipelas of the face with high fever.- 16th. 30 dr., m., cutting pain in belly, pains in sacrum; sudden sore-throat.- 17th. 5 dr., pains in bellyandback less, some diarrhea.-18th. 2 dr., repeateddiarrhea; pains less. (Ibid., 472.) 17. W. T-, a girl, æt. 19, always regular in menses from her sixteenth year, but nomenses for nine weeks. Sept. 28th. 5 dr.tinct., after h., headache and vertigo. -29th. 10dr., roaring in ears, shooting in forehead.-30th. 15 dr., restless at n., shooting in belly, roaring in ears.-Oct. 1st. 20 dr., only roaring in ears.-2nd. 25 dr., sometimes black, sometimes yellow before eyes, sometimes diplopia ; traces of menses.-3rd. 30 dr., roaring in ears, dimness of vision; traces of menses.- 11th. 1 dr., vertigo greater than before, dim vision, spots before eyes.- 12th. 2dr., spots before eyes, vertigo, especially when walking ; loose stool.- 13th. 3 dr., same symptoms.-14th. 4 dr., violent frontal headache, spots before eyes.- 15th. 6 dr., only roaring in ears.-16th, 15 dr., some roaring in ears.-17th. 25 dr., increased secretion of urine, e., roaring in ears.- 18th. 30 dr. , violent frontal headache which lasted all n. (Ibid., 473.) 18. D. T-, girl, æt. 16, had her menses 8 d. previously.-Sept. 28th. 5dr. tinct., shooting frontal pain; exhaustion.-29th. 10 dr., stabbing in both temples, as if with apointed knife. -30th. 15 dr.,menses came on after 10 d.-Oct. 1st. 20dr., heat of head, feeling as if head turned round in bed; great inclination to vomit ; menses increased.-2nd. 24 dr., in e., heat of head, restlessness and exhaustion.- 3rd. 26dr., menses continue.11th, 1 dr., only heat ofhead.- 12th. 2dr.-13th. 10 dr., same symptoms.-14th. 15 dr., heat ofwhole body, violentfrontal headache, all d., diplopia ; no appetite.-15th. 16 dr., immediately violent headache in temple, thenheat,thirst; n. sleepless.- 16th. 20dr., some frontal headache and vertigo ; n. sleepless ; appetite diminished, no stoolfor 2 d.-17th. to dr., headache, vertigo, thirst, drank 8 glasses of water.-18th. 5 dr., same symptoms. (Ibid., 474.) 19. S. F-, girl, æt. 21, menses regular since 14th year, none for 1 year. Sept. 27th. 5 dr. tinct., no effect.-28th. 10 dr., immediately vertigo.-29th. 10 dr., noeffect.-30th. 15 dr., vertigo all afternoon ; occasional dim vision.-Oct. Ist. 20 dr., heat of head, till e.; slight vertigo, dimness of vision less.-2nd. 25 dr., vertigo,

• Cases 14 to 27 inclusive were girls in a Lock Hospital who had been under treat. ment for gonorrhea, condylomata or excoriations of vagina. They had mostly some derangement of menstrual function, but were otherwise well.

heat ofhead, some perspiration. Since yesterday papular eruption on forehead.- 3rd. 26 dr., heat of head; bellyache at n. (Ibid., 475.) 20. L-, girl, menses always regular, but none for 7 weeks.-Oct. rith. 3 dr. tinct.,headache in e.,disgusting taste,much thirst at 1.-12th. 6 dr., at n. sleepless, thirst, heat andheadache; great exhaustion.-13th. 8 dr.,sleep restless, heat ofbody and sweat; headache with great exhaustion and disgusting taste. -14th. 10 dr., only bitter taste. - 15th. 15 dr., frontal headache, then heat of all body, no sleep at n.- 16th, 25 dr., felt occasionally as if bed turned round ; dark before eyes.- 17th. 15 dr., in afternoon attack ofvertigo and dim vision. (Ibid., 475.) 21. H. F-, girl, æt, 26, miscarriage 3 months ago.-Oct. 10th. 5 dr. tinct., no effect.- 11th. 10 dr., pains in belly.- 12th. 15 dr., low spirits for 1 h., inclination to vomit, for 2 h. headache.-13th. 10 dr. , pains in belly.- 14th. 25 dr., nausea all afternoon,weak and disinclined for work ; drawing in-sacrum ; stool loose.- 15th. 30 dr., inclination to vomit; disinclination for work. In e., spasmodic pain in belly.adache ; n.very restless 16th. 35 dr. , immediately pains in belly, and headache rath restless.-17th. All forenoon pains in belly made him keep his bed. (Ibid., 476.) 22. H. E-, girl, always healthy except that menses often stop for year ; the lastmenses 6weeks ago.-Oct. 10th. 5 dr. tinct.,slept betterthan usual.- 11th. 10

dr., afternoon, mist before eyes.-12th. 15 dr. , all afternoon and n, troubled with pains in belly, stool loose.- 13th. 20 dr., restless at n, owing to frontal headache.- 14th. 30dr., all afternoon spasmodic pains in belly and headache, especially in forehead.-16th. 35 dr., violent pains in belly all d., mist before eyes ; shooting pains in forehead; very restless 1.-17th , 2 dr., violent spasm in abdomen, frontal headache. (Ibid.,476.) 23. R.A-, girl, æt. 25, always healthy, except subject to violent spasms in abdomen, and irregularity of menses; has had none for 3 months. Sept. 28th. 5 dr. tinct., violent spasm in abdomen, headache and vertigo all afternoon.-29th. 10dr., heaviness of head.-30th. 15 dr., great ebullition ofblood in head, violent headache, anxiety, dim vision. Oct. 1st. 20 dr., immediately vomiting, again in n.; pretty soon diarrhœa ; towards m. vomited again, then sound sleep.-3rd. 20 dr., in e., inclination to vomit ; dim vision, diplopia ; at n. profuse sweat, headache ; in m. very exhausted and prostrated.-4th. 24 dr. , menses appeared. (Ibid., 477.) 24. S. M-, girl, æt. 18, healthy, menses regular, the last 8 d. ago.-Oct, roth. 5 dr. tinct., after pains in abdomen, menses reappeared.- 11th. 10 dr., after rh. vertigo and dim vision; later vomited mucus twice.- 12th. 12 dr. , immediately vomited twice food and mucus, with vertigo, exhaustion, vision of colours, diplopia; restless at n.- 13th. I dr., no symptoms.-14th. 6 dr., vomiting, followed by exhaustion, vertigo, dim vision, frontal headache ; restless n.- 15th. 7 dr., vomited twice greenish fluid, preceded by headache, vertigo, dim vision ; feels weak and perspires much; restless n., disturbed by great heat. Has had nausea 4 d.- 16th. 6 dr., vomiting of green fluid. (Ibid.,478.) 25. K. P-, girl, æt. 25, always healthy, no menses for 3 months.-Oct. roth. 5dr. tinct., some nausea with headache; vertigo in e.- 11th, 10 dr., towards e. vertigo, then headache, drawing in sacrum.-12th. 15 dr. , towards e, inclination to vomit, vertigo, exhaustion; low spirits; n. restless, loose stool.-13th. 16 dr., loose stool; towards e. headache; n., sleeplessness on account of violent pains in belly. In m., great inclination to vomit, exhaustion, vertigo, dim vision.-14th. 20 dr., pain in belly, especially n.; nausea, anorexia.- 15th. 25 dr., all n. nausea, inclination to vomit, drawing in sacrum, vertigo, headache. (Ibid., 478.) ER 26. E. R-, strong healthy girl, menses always regular, but the last has continued 4weeks.- Oct. 11th. Idr. tinct., in e, headache.-12th. 2dr., m. and e. headache . -13th. 3 dr., ringing and shooting in ears, especially at n., with headache.- 14th, 4dr., ringing and shooting in ears, eructations.- 15th. 10 dr., spasmodic pain in abdomen.-16th. 20 dr., very violent frontal headache, vertigo, roaring in ears.- 17th, 21 dr. , headache continues.-18th. 25 dr., same report. (Ibid., 479.) 27. E. F. , robust girl,the menses, usually regular, have not appeared for 2 months. -Oct. 11th . 2dr. tinct., in e. headache.-12th. 4 dr., same symptoms.-13th. 6 dr., headache slight ; stitches in l. side.-14th. 10 dr., stitches in side continue.-15th. 15 dr., spasmodic pains in belly for some m., they suddenly cease and recur.- 16th. 20dr., stitches in r. side.-17th. 25 dr., no symptoms.-18th. 30 dr., same report. (Ibid., 479.)

1. N. N-, suffers from weak sight, can only readby d. for 1 h., in e. still less.- Oct. 13th. 5dr., 1st dil.- 13th. 10 dr. , no symptoms.-14th. On rising in m. great headache and flickering before eyes. The headache lasted alld., and next d. in equal severity, diminished 3rd d., and ceased 4th d. The flickering before r. eye lasted 6d., andwent off entirely on 7th d. It was still observed in l. eye in a slight degree for 3 weeks. The sight inclined to get worse every d. Objects seemed veiled. On 7th d., the outlines of even large objects were indistinct, andhe could not read byd. or n. The candle flame appeared like a luminous ball. This went off in r. eye after 8 d., but in the l. eye it continued till Nov. 3rd. He noticed, when eyes were open or shut, at a distance of about 2 feet a dark disc about the size of sixpence, which was often traversed by flashes as of lightning. This symptom went off after 8 d. After this the l. eye seemed to be looking through a dark blue glass. This phenomenon continued till Nov. 3rd. At first the stools were more frequent for 3 d. Urine also increased. (Ibid. , 480.) 29. a. LEMBKE .-Oct 3rd, 7 a.m., 10 dr. tinct. 8 a.m., continued pressure in stomach with distension and fulness. Frequent urination and much clear urine.-6th, 7 a.m. , 20 dr. No effect.-10th, 8 a.m., 30 dr. 7.30 p.m., without griping a sudden copious liquid stool.- 12th, 7 a.m., 40dr. Severe drawing in 1. leg from 10 to 12 a.m. I p.m., violent cutting at back of l. inner ankle when walking ; pulsating tearing on under aspect of r. toes for a few m. Scraping in fauces all d, Burning and rancid eructation of air, very frequent, eating has no effect on it, almost all d. 2 p.m., burning and shooting on 1. side of tongue, repeatedly. In 1. some pressure and painfulness as after a blow or great fatigue, whilst walking, lasts some m.; drawing in l. big toe. No stool at usual time. E., burning intip oftongue.-13th. Increased redness of tip of tongue with several small vesicles, frequent burning in it, making speech and chewing painful ; flow of saliva; fluent coryza, -14th. Coryza gone ; the symptoms of tip of tongue continue in undiminished intensity ; saliva tastes salt and so does all food ; tongue white. Frequent tickling in larynx and dry cough.-15th. Much slime in mouth ; fauces red ; tongue symptoms unaltered; sudden scraping in larynx ; sudden severe tearing in r. frontal bone ; slight jerking through upper teeth.- 16th. Much mucus in fauces ; tip of tongue red, burning, studded with small yellow vesicles ; sudden violent boring in 1. parietal bone; repeated tickling and scraping in larynx, with dry cough ; lachrymation of eyes and accumulation of watery saliva ; violent scraping in fauces and pain there when swallowing.- 17th. Fauces very red, painful when swallowing, much viscid mucus there ; tongue better ; frequent coughing ; violent sharp stitches in region of 1. nipple, lasting some m., twice repeated at 4 p.m. when walking. Atn. violent cough, much scraping in larynx ; pain and thick mucus in fauces ; salt taste ofall food.- 18th. Same state ; especially repeated sudden attacks of violent tickling in larynx with some fits of coughing ; pain and much mucus in fauces ; rough voice ; slight burning in tip of tongue. At n. severe cough and tickling in larynx. -19th. Samestate, but especially at n. violent tickling in larynx with severe dry cough and pain in throat. Several times at n. sudden discharge from nose of a large quantity of clear watery-looking mucus without sneezing (his coryzas are generally attended with marked sneezing). Much speaking or walking even against cold wind never caused or excited the fits of coughing,which usually were worst in sleep,

For several n. has passed much clear urine which bears no relation to the quantity drunk. Thequantity did not vary whether the room was warm or cool.-20th. All symptoms gone. b. 29th, 9 a.m., 40 dr. Liquid stools at 10 and 10.30 a.m. Repeated shooting in rectum at 12 and 4 p.m. Much scraping in larynx and dry cough. On same d. coryza with much sneezing, cough, and expectoration of mucus, scraping in larynx, rough voice.-Nov. Ist. Slight fever, some heat, and confused head. The cough, which was at first, especially at n., violent and dry, with much tickling and scraping in larynx, was afterwards accompanied by white, yellow, and green expectoration. By the 12th it had nearly ceased. The coryza lasted till the 20th.-20th, 7 a.m., 40 dr. Confusion and heat of sinciput at 7.30 a.m., lasting several h. Soon after taking med. scraping in fauces all d.-Dec. 19th, 7.30 a.m., 50 dr. Head confused; pressure in lumbar vertebræ, aggravated by bending and pressure, lasts all d. with intermissions.-30th, 6.30 a.m., 60 dr. 7 a.m., sinciput confused and heat for 2 h. No other symptoms. (LEMBKE, N. Z. f. h. Kl., iii, 65.)