Juglans regia
de Richard Hughes & Jabez P. Dake — A Cyclopaedia of Drug Pathogenesy
Volume III — Main text
Juglans regia. Walnut.
I. Proviftgs.—i. a. Cl. MUller, nt. 14, Dhle^atic-choleric temperamcnEa >■ good health, took Sept. amd, 184a, 9 a.m., 10 ar. tmct. of outer hull. After § b. repeated eructations. — 13rd. 10 dr., frequent eructations, sometimct witb hicCTipt good appetite. After dinner distended abdomen and discharge of nnicb flaina. 4 p.m., very copious soft stool, latterly nearly liquid, abdomen much dirtcadcd all d. — 24th, 30 dr., soon violent eructation. After 1. h. pain in 1. side of ■**'ttmiHi under false ribs, increased by deep breathing, laughing, and stooping, till 6 pja. About noon frequent flushes of heat with conhision of head and pretuve pain ~ eyes, worse on moving. In afternoon frequent yawning and stretching. Ap| good, no stool. — 15th. 40 dr., after ^ h. much eructation, pain in 1. side ttf m men only when walking quickly, extending almost all over abdomen, appetite goods abdomen greatly distended. 7 p.m., stool scanty and hard, with straittmg.-ii-aAdl. No med., abdomen still distended, no stool. — i7tn. 60 dr., immediately nauaea and feeling ot burning in stomach, eructation ; on walking quickly dull pain on 1. aide oC abdomen, head confused and pain in forehead, especially when shaken and on eyes, till noon, z p.m., healthy stool, afterwards disagreeable feeling of fulness of abdomen. — 28th. 100 dr., during forenoon violent loud From 1 1 a.m. occa.sional flushes of heat and coldness, with heaviness of head, increased to pain after eating, but was gone by 3 p.m. After 4 p.m. itduar long time on hack of r. hand, making him scratch, then on foot, forehead^ ] scalp, abdomen, but nothing visible on bktn. No slool, distended abdomen, a flatus, profuse discharge of urine. From 9 p.m. till he went to sleep hot with cold extremities. — 19th. No med. On waking m., tongue furred white* bitter, slimy taste. Afternoon, normal stool, much urine. £., burning hot bead and very cold extremities, pulse quick.— From Sept. 30th to Oct. $th no med., no nmptoms. — Oct. 6th, 9 a.m., 40 dr. tinct. of leaves. Immediately nausea, nasty bittv taste lasting i h., frequent eructations. 10 a.m., pressive pain in forehead, etpeci^ly over], eye and in eyes; in nose and head feeling as of commencing cor)-za,confuaionp sometimes vertigo, but very good appetite and normal stools. From 4 P.m. bead free and light. Passed 56 oz. urine 01 normal character, no increase of thirst.<^7tb. Slimy taste on waking, and tongue covered with white mucus. 9 a.m., 60 dr., after which violent eructation, distended abdomen, normal stool, 61 oz. dark red urine,— 8th, 9 a.m., 80 dr. Eructation, headache especially over 1. eye; no stool, 64 Ob urine. — 9th. No med. Normal stool, urine 40 oz. — 10th. No stool, urine 44 oa... nth. Normal stool, urine 38 oz. — nth to iSth. Daily normal stool, urine ftoni 40 to 45 oz. — 19th, m., 40 dr. tinct. of hull. Repeated eructation, normal itoid, 47 oz. of normal urine. — zoth. 40 dr., soon nausea, retching. After 1 h. aligibt wandering pains in bowels, confusion of head, burning in eyes, a p.m., normal stool. Thirst, urine 55 oz., passed at six time!*, once in middle of n., quite unumal. — 2 1 St. 60 dr., violent eructation and flatulence. After i h. confusion and *
ne«s of head, pain in forehead, especially 1. side, general weariness and disinclination for usual occi)pation&. After dinner head free and light; no •ttool, 46 oz. urine. To>d.iy and yesterday burning. itching in anus, very violent, compelling constant iicralching.^iiQd. Mo med. Forenoon, when sitting, very severe short stitches in sacral region, making him start, stool ^-ery 6rni, urine 54 oz. — a^rd. Nothing but trequcnt itching in anus and copious di&chargr of urine. — 14th. No stool. Itching in anus very severe in bed at n. in fits of about 5 m. ; painful stitches in anus, so that he must frequently rise up, and for a h. could not sleep.
b. Sept. 7th, 1844, took ao dr. of tinct. of leaves. After i h. slight drawing in bowels, abdomen distended, extreme hunger, constant itching on r. hand. 8 p.m., ^ after supper, nau^a, loathing of tobacco smoke, tliscontented feeling. In bed there came on burning and itching on skin of lower extremities, arms, and body, here and there, with restless tossing about and inability to sleep. Unusually copious urine. — 8th. No med., no symptoms. — grh, m., 5° ^- Repetition of the drawing in hypogastrium, eructation, flatulence. After 1 h. frequent shooting and itching in r. thigh, in afternoon in fingers of r. hand. 5 p.m., copiou«i stool, followed by burning pain and pressing in anus, con^^tant urging to urinate, the urine dribbles away involuntarily. — loth. 50 dr., after i n. the drawing in abdomen recurred, with slight pressure in spleen and eructation, pain in forehead over eyes with giddiness, itching on skin here and there. On nape small pimples, exuding when scratched (ordinary acne). In bed, e., excited as if tipsy, felt as it hovering in air.— iith, 9 a.m., 80 dr. After ^ b. drawing and Umc feeling in legs and knees, with peculiar weakness interfering with walking on account of frequent giving way of knees until noon y a similar but slighter feeling in r. hand, lasting only a short time. Some pressivc pain in forehead. In afternoon itching in several fingers of r. hand. 5 p.m., peculiar drawing pain in first phalanx of 1. thumb and wrist, worse when moved, not mcreascd by pressure, as if dislocated, lasting all c. In bed, same pain in r. big toe, many and restless dreams. Much urine.— lalh. On waking m. pain in thumb and toe still prrsent^ chat in toe gues ufT after getting up, but that in thumb la^ts all d., often only when moved, hut occasionally when at rest. — 13th, 9 a.m., 70 dr. Thumb still painful. Frequent irching and burning in anus. Ct p.m., nausea, very bitter taste, collection of saliva in mouth, frequent yawning, good appetite. — 14th. Thumb still sometimes painful, sometimes the same sensation in r. index. Three pimples on the face. Burning in anus. — 16th. 30 dr., two fresh and larger pimples on mouth. Was travelling till Sept. 34th, The pimples healed up after becoming pustular and forming scabs. In beginning of October took 3 times at intervals uf 3 d 30 dr. ist dec. dil., which caused symptoms similar to those recorded, but milder. — t2th and iSth. 30 dr. tinct., same symptoms, only stronger, appeared. About this time ihe r. axilla began to itch and bum, and the skin became sore and chapped. In Nov. the skin was quite red, desquamated, exuded, and a patch of eczema as big as half.a.crown appeared, with vesicles at its margin, which burned violently. The eC2croa became much worse after getting in a perspiration, sweat and discharge together made the linen grcenish.ycllow and stiff. Sometimes the pain was so severe that movement of the arm was impo&.sible. The increased burning and itching was alwaj-s attended by an aggravation and extension of the eczematous patch and vesicles, which came on a few h. after the burning. In Dec. a similar eruption came in the r. axilla, but never got so bad as the first. In Jan, a small furuncle appeared on the coracoid process of the r. shoulder, which suppurated and healed up in a few d., then on Jan. loth a very large painful boil came on the biceps muscle about a inches above elbow, with a hard and red areola, that after poulticing discharged much pus and then healed quickly. — Feb. 8th. There appeared on the r. elbow 1 red spots an inch square, which itched violently, and on which a small yellow ulceration filled with pus appeared. They lasted about i week. — nth. The eczema in axilla not yet gone. — i6th. In r. axilla hardly anything to be seen, but in 1. there is a fresh eruption ot small burning vesicles, which afterwards form a rrtl exuding spot. The burning and discharge much increased by sweating, and the linen is stained greenish yellow and stiffened to a large extent.— i8lh. A large boil appeared on r. side between ninth and tenth ribs, with considerable hardness and violent pain ^ it burst after 9 d., and discharged thick bloody pus, but soon healed, but left considerable hardnes.s for a long time. In the middle of February there appeared on the arm, not far trom the seat of the second boil, a red spot, which gradually rose up, at the end of 10 d.
nttainril the si7c nf a hazel-nut ami frit rathrr hard, something like s smmll mcyited tumour or an iniluratcd glantl, but quite painle<««. About the same time as chc trniihli- in the axilla ramc there ajipeared. first on the 1. in«tep ihen on the r., a peculiar i-utuiicous affection, which MKin became trouhlesomrt a red itching^ place the uie ot lialt-a-cruwn f on it zntsc small pimples, which became covered with small hard scabs. The whole spot became graJually elevated and ver)' painfull the small scab* caused severe pain when pressed on by the bi>ot. When they were icratched off healthy epidermis wa< found beneath them. Thi« alfeciion continued till March, and then gradually went off, but the part remained during the next ^tw moathi of a bluish-red colour, and wa> swollen. By May the eczema in the axillae iw completely trone, and aUu the small hard swelling on the arm, only a red colour remained there — May icth to i6th. Took every other day 30 dr. ittt dec. dil. On the sndd. felt a violent burning and itching, and there came a red Apot size of faali-a-crown ou The outer side at forearm near elb«*w.joinr, in the centre oi which a small pimple rote. Next d. the red spot had disappeared, but the pimple increased in Hxe, was venr painful, and pus appeared in it, but it disappeared without bursting, and After 6 d, it was quite gone. He had never before suffered from any skin af&ction. ^HjiggM^ xxii, 70.)
z. a. Laurenz Fritz, surgeon, xt. 25, venous-bilious constitution. Sept. x6th, 1842, took 10 dr. tinct. of hulK. No symptoms. — arth. After ao dr., cmctatioii, distended abdomen, hard stool. — zSth. 30 dr., violent eructation, distension and liardne<^s of abdomen, flatulence, great hunger all d. — X9th. 40 dr., yesterdaj** symptoms recurred, the flatulence wa.« vef)- truublesfime, stool hard, frequent micturition, double the usual quantity of urine, causing htm to get up at n. — 30th. 70 dr., after 3 h. pressive pain on 1. side of abdomen, with wandering pinching in bowels^ abdomen very distended and hard, very hard stool, with little relief to abdiHDen, Urine copious and frequent. — Oct. ist and and. Same symptoms, but slighter.
b. Oct. 3rd, 5 a.m.. 40 dr. of tinct. of leaves, eructation. — 4th. 80 dr., fiata* Icnce, rumbling in abdomen, firm stool» tympanitic distension of abdoment with unusually ^reat hunger, but not increased thirst, passed a or ) times the usual quantity of dark red urine, had to get up 3 times at n. to pas^ it. — 5th, 6th, ytb. Same symptoms. — 4th. After coitus slight burning in penis, and there appeared a chap or excoriation where the prepuce is attached to penis. This increased, and after S d. developed into a suppurating stripe several lines in breadth half way round between glans and prepuce. Then it took on a worse appearance, the ulcer bccaosc deeper, its borders hard, its fundus lardaceous and easily bleeding, it looked veiy like a i liaiuTe. Often slight crusts formed, but the suppuration continued under these and they i'ell off, leaving the suppuiating ulcer as before. Thus 19 d. passed, during which the ulcer continued to increase. After some d. more there was formed on the centre a firm healthy scab, which eventually fell off, and the skin beneath was healthr. The ulcer nt>w changed into 2 small round ulcers, in appearance ju5t like typhilia. These little ulcers became covered with scabs, and when they fell off the ulcers were healed. The whole process lasted 37 d.
c Sept. 7th, 1844, m., took 30 dr. ist dec. dil. tinct. of leaves, the same 9th and nth. Flatulence, eructations, distension and hardness of abdomen, copious secretion of urine. — 13th, 15th, 17th. 10 dr. tinct., same symptoms. On 17th oliscrvtil a swelling on 1. check and upper lip. (During the la^t two years had suffered severely from toothache and gumboils in 1. upper incivirs, though the teeth were sound.) Now on the same place there came on swelling without toothache, and after 5 d. the cheek over this pan commenced to swell. — 14th. On 1. cheek a hard, red, very painful swelling, in the centre of which, 14 in, from ala nasi, was a nomsal, snarply-defined circular depression, dark red, soft, and yielding. Suppuration outwards being threatened, the to<Jth was extracted, and a large quantity ot pus was discharged through the hole thus made. In a few days the swelling and redncaa wtre gone. (/W., 79.)
- Dr. M. MUller, art. 58, of lively, irascible temperament, quite healthy, took, Dec. 6th, 1842, 8.30 a.m., 10 dr. of tinct. of hulls. After ^ h. slight pain in boweb above navel. After i h. urging to urinate. After 1 h. scanty discharge of clear urine. After 2^ h. rheumatic pain in interior of knee-joint lor i m.. rendering walking difficult. After 4 h., contrary to custom, is calm and comfortable, intellectual Iuziue>^, no inclination for speaking or quarrelling. After 3^ h. no inclinatioa
10 drink during or after dinner, he feel« a kind ot pirasurc in keeping his moutli ilry. After 6 h. Ie^« urine than mual. After 6^ h. cannot have lii« iiMial \icsta, though he fell disposed tor it earlier than usual ; electric shock* in both Forearm'i and hands woke him up as toon as he be^n to «leep. Urinates at 4, 6, and 8 p.m.. each time hut little urine form5. At supper Ktill without thirst, doc« not rclt^h hi!> wine, is inattcnti-c when readings, pulse quicker and fuller than uiual. {Il'uJ.t 84.}
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Edward Begand, surgeon, art. 35, of robust conMinition, and lazy apathetic mind, took. Sept. 5th, 1S44. 5 dr. tinct. of hulls. No symptoms. — 6th. 40 dr., eructations, flatulence, distended abdomen, ^reat appetite, hanl ttool. During d. frequent short stitches as if in both lungs, not affected by breathing or moving. — 8lh. ^o dr. tinct. of leaves caused eructation and flatulence. — nth. 60 dr., after ^ h. violent eructations and rumbling in abdomen; e., pre ^sive pain in head, especially forehead. Frequent erections d, and n. — itth. 60 dr., eructation and flatulence, rcstlc&» sleep at n, on account of itching of i^kin in various places ^ many dream.^ and erections. — 13th. 80 dr., eructation, rumbling in belly, transient stitches in chest and discharge of much flatus; 8 or lo erections during d. — From 14th to »olh, when he took no mcd., eruption of small red papulc-s, some of which were larger and contained a viscid fluid (a Kind of acne), apprnrrd on neck, face, shoulder, and back. Frequent erections d. and n., restless sleep and frightful dreams. (Wtii., 85.)
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Otto Kesslkr, Divinity student, x^t. 23, of scrofulous h.ihitns took, Oct. 7th, 1841, 10 dr. of tinct of hulk Frquent eructation, distension of abdomen, rumbling, and flatus, a fluid stool. — €th. zo dr., abdomen tympanitically distended, 1 liquid stools, head confused and heavy, hawked up much mucu% and mutt urinate frequently and copiously. — 9tb. 40 dr., abdominal distension m> great that in spite of good appetite he dared not eat much on account of the feeling of fiilness no stool, violent headache (to which he was accustomed). — loth. 50 dr., increase of yesterday's symptoms, stool after much straining, urtnc about double the u*ua] quantity, though thimt wa^ not increased. — nth. Stool hard, urine still copious, abdominal distension less. (IhiJ.. 86.)
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Dr. ICUcHENMEisTVR, ffii. a6, Sept. 4th, 1844, took so dr. tinct. of hulls. Soon, great eructation, and in afternoon a frequently recurring itching on sternum, compelling scratching. — 5th. 10 dr., eructation, oppression of chest, frequent itching of hands, and uncommonly good appetite. — 6th, 7 a.m., 30 dr. Forenoon, shooting in 1. hypochondrium under lowest ribs for wmc m., continual eructations. About noon, pain interfering with walking in r. patella. During dinner sudden call to stool, with extreme ftilneu in abdomen, and on the way home shooting and hindrance to walking, as if in inner side of condyle of tibia at knee-joint, for 10 m. Then stool, broken up but not hard, and anotlier at a. 45 p.m. — 8th. 45 dr., besides eructations, fulness of abdomen, pain in I. leg similar to that ot 6th, very transient. — 9th. Dull tearing toothache in carious teeth, worse in warmth of bed, and going oflF towards m.— I oth. 50 dr., forenoon, a hitherto unknown megrim in a spot onT. parietal region, the size of a crown, lasting some hours, and becoming at one time so severe when speaking that he had to cease; went off" after 1 h. — nth, 14th, i6th. Took each d. 40 dr. Observed the following gastric s)'mptoms : hiccup, especially after greasy food, to a very violent degree; fulness causing necessity to go to stool ; stool m. and generally again between i and 3 p.m., one afternoon a ^ttooU, ne%cr verj copious ; flatus that came away chiefly when lying i appetite only once affected, then, though hungry, he did not relish his dinner. Thirst increased, drank much. An old eczema which he had had for years on dorsal aspect of thumb, the size of a sixpence, which had almost di<iappeared under mezereum, commenced to itch and got red and sore. (IbiJ., 86.)
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Paul Radelli, cabinet-maker, set. 2t, of robust frame. — Oct. i8th, 1841, m., 10 dr. tinct. of hulls. Eructation and flatus. — 19th. 10 dr., sickness and inclination to vomit, soon followed by pressive pain in epigastrium, and distension of abdomen. 1 1 p.m., woke suddenly from sleep, and vomited the food he had taken 3 h, before. — lotn. 40 dr., nausea, rumbling in abdomen, flatus, stool with much straining; copious discharge of urine. — list. After 50 dr. violent pain all through abdomen, somewhat relieved by eructation or discharge of flatus; urine so much increased that he had to pass it 7 times, whereas his usual number was j. Two stools, — xind, 31 dr., much flatus profuse flow of urine. — 16th. 71 dr., could not butcaw. clothe% the distension of abdomen was so great, at sakSiuc Vwsvt V\s\«v\ -^xtvww.^ "«»■
Ktomach till no<Hi, urinated t times in coune of fermoon. Appetite vcrj great, j stool?> with great »traiaing.~s7th and ilth. Still shooting pauu in hypoganric region when moving and stooping ; urine very profuse. (IHa,, SS.)
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A. KuRTZEL, let. 33, robust, nervous, bilious temperuncnt, took 8c|it. aClh, 1843, m., lodr. tinct.ofhulls. Great appetite— a7lh. 10 dr., thin stool, coiilnMn of head, distension of abdomen, frequent eructation. — s8th. 30 dr., 10 mjm.^ aoft stool, heaviness and dull pain in head. ) p.m., a second thin stool, occvuonal acconnlation of saliva in mouth. From noon, buming hot hands and quick puW (9 pjB, lolt). £., perspiration all over. — S9th. 40 dr., confusion of head, % liquid itDob before noon, good appetite. 4 p.m., another liquid stool with fiill, hani abdomen, aod much flatus. £., heat in whole bodv, pulse 86.— From 30th till Oct. 3rd no ncd. Stools regular. — 4th. 50 dr., 5 liquid stools with rumbling and pinching in bowels, but constant good appetite— 5tn. 55 dr., 3 diarrhoric stools with rumbling.— 6th. 60 dr., a diarrhoeic stools, tongue white, bitter taite, anorexia and headache. (IbiJ, 89.)
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Carl Tenzler, medical student, st. 19, strong, healthjr, Oct iTth, it4a» took 10 dr. tinct. of hulls. No symptoms— iSth. ao dr., in e. dull headache ana exertion. Stool normal, urine very scanty. — 19th. 30 dr., after dinner abdomen foil and distended, urine scanty. — aoth. 40 dr., abdomen very tense and full | after dinner dull headache. Stools always normal, urine always scanty, (ttid.^ 90.J
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Th S — , housemaid, art. 26, menses since 16 always regular.— Oct aiat, m., 10 dr. tinct ot Itraves. Slight nausea, and disagreeable feeling of fulness of abdooicn. — sind. so dr., drawing pains in abdomen, nausea and retching. — ajrd. 30 dr., violent pains in whole lower part of abdomen and nausea all d. with short interrak. — 14th. 40 dr., abdominal pains very severe, preitking and drawing, aKgravatCKl hy movement, menses came on 15 d. too early, whereupon the pains modmited. For the next 8 d. the menstrual discharge was profuse and blackish, often large lumps came away, the discharge used only to last 3 d. She also complained m gcncisl weakness and anorexia. — Nov. 2nd. 30 dr., 2 stools, preceded by piDching.— -jid. 40 dr., 4 liquid stools with pressive pains in belly. — 4th. 50 dr., 4 djarrfaioeSc stools with pinching. Urine not increased. The three nextd. the stooIswerenormaJ, no pain in bowels. — 8th. 60 dr., distension of abdomen, with frequent discharge chT flatus, rumbling in bowels, and pressive pains in epigastrium; 4 diarrhoeic stooli.^ — 9th. 70 dr., same abdominal symptoms, only more violent, preuive pains in fort' head. Appetite good. — loth. 80 dr., diarrhcea and frontal headache, and pains in abdomen continued for some d. (IbiJ.^ 91.)
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a. Oct. 1st, 1869, I procured a walnut, and after bruising it, hull and all, prepared a tincture with 95 per cent, alcohol. On 28th of same month, at 10 I took 5 dr. of this tinct. in 45 dr. of water, which was followed in | h. by tions tasting of the drug; at jx took 10 dr.; eructations tasting as after eating fio, and considerable yawning. 19th, 9 a.m., 20 dr. 3.30 p.m. 25 dr.; no new nmptoms. Bowels confined since commencing proving. 30th. — Had evacuation non bowels ; urine increased at least one half in quantity. At iz took 30 dr., and at 4, 35 dr., followed by eructations and flatulence. 31st. — At lotook^o dr. At I took 50 dr., which was followed in \ h. by throbbing in both temples, and a sharp pain in front part of head, relieved by going into open air, and returning on entering the warm room. Nov. 1st. — Headache continues; increased flow of urine; boweht confined. At 10 took 60 dr.; at 12 80 dr. Had ouite natural evacuation from the bowels. The increased urination, eructations, and flatulency were now becoming rather annoying. At 3 took 90 dr., and at 8 had sharp cutting pains in r. hypogaatric region, lasting a few m. At 9 took 100 dr. Slept well during n., and all next d. had frontal headache, with yawning, and great desire to sleep. 4th. — Headache, and flushed face; no evacuation of bowels ; urine diminished in quanrit}-. 6th.— Mjr r. ear aching, with feeling of fulness, and on 8th my left ear commenced in same way, I then had a discharge of pus from both ears until Dec. loth. External part of r. ear was very much inflamed, and had two large and painful sores on it, similar to thoae 1 had seen on children who had eaten freely of the nuts.
/'. Three months later (March ist, 1870), feeling quite well, I took at 11 a.m. lo dr., and at 1.30 20 dr., followed in ^ h. with eructations tasting of dnig, waA increased flow of urine. At 8 took 20 dr., which was followed by sharp lancinating pain in forehead for several m. ; and after lying awake for an h. that n. slept welE
snd. — At 10 and is took lo dr., and at 2.30 ray I. car commenced burning severely; became very red and swollen, and before bedtime: a pimple began to term on the inside ; slept well during n. ^rd. — BoweU constipated, 9, took +0 dr. j no new iiymptomt. iz, took 50 dr. j 3, took 60 dr. Burning in 1. ear increased. $^ took 70 dr., and at 9 took loo dr. For 8 d., to nth, I bad a discharge of pus from my ears (I. more than r.) with severe burning and redness of the external [.) car. When walking, there ^vas a feeling a> if something wa« dropping inside the ear at every %tcp. During the greater part of the time that I wi$ taking the drug I could not lay the 1. side of my head on the pillow, on account of the soreness. (For vcvcral years during the winter I had been annoyed with a burning itching eruption on the lower extremity, always commencing a.> soon as I would undress. After taking the Jiiglans regia I was relievett of that trouble.) (H. L. SOOK, M.D., OAio Med. and Surg. Rfp.y iv, ai6,)