Zincum iodatum

por Richard Hughes & Jabez P. DakeA Cyclopaedia of Drug Pathogenesy

Volume IV — Main text

Zincom iodatmn, Zincic iodide, Znl,.

  1. Proving!. — i. Joseph Rhodes, jet, 24, health good. Proved 3X trit. in 2 gr. powders, ist, 2nd and 4th d. — Took powder in m., which caused temporary nausea (as sac. lac. does), soon relieved by food. On latter d. repeated dose at 3 p.m., when nausea was followed by burning in stomach and cramp-like pains in bowels. These soon passed ol^' while walking. Doses were repeated on 6th and again oo iqth d., with no further effect. {Trans, of Amtr. Jnst.^ 1888, p. 167.)

  2. H. E. KisTLER, XX.. 29, took 5 gr. doses of same 8 times in ad. No effect was observed, save, an h. after first, painful undulation from free border of ribs, r. side, upwards to 3rd rib, lasting 10 m. {Ibid.)

  3. Everett B. Finnev took 3 gr. of same 8 times in 4 L without any effect. {Ibid.)

  4. D. M. Landis, xt. 24, healthy, took 3 gr. of same 12 times in 3 d. without result. On 4th d. took 5 gr. at 9 a.m., 1 and 6 p.m. In afternoon felt very sleepy, with slight headache, continuing till e. At 5 p.m. felt slight pain in 1. lumbar region for a short time. On 5th d. took 5 gr. 4 times. Symptoms of previous d. recurred. On 6tb<L repeated dose 3 times. At different intervals felt splinter-like pains in throat. Very sleepy p.m., with headache, which continued till late inc. On 7th d. repeated dose at 9.25 a.m. and 1.30 p.m. Headache between 8 and 9 a.m., beginning again at 3.45 p.m. and continuing rest of d. At 12.30 p.m. cramp-like pain in I. thigh, which continued till 3.45 p.m. On 8th d. pain in thighs again, felt after rising early, but gradually subsiding after 8 a.m. (Ibid.)

  5. a, John N. Yates, xt. 47, feels well, though dyspeptic, but urine, 29 oz. daily, leaves dark deposit on sides of vessel, and is slightly albuminous. Has stool only every other d. After a negative test with sacch, lact., took i gr. of 3X trit. at 7.30 a.m. In 2 h. cold danamv sweat in palms 5 tremulous feeling in lower extremities, followed by shifting crampy pains in muscles of legs ; the same tremulous feeling and muscular pains were present in arms, but came on later in d. At 9.30 a.m. peculiar feeling of coldness in stomach and bowels, with tendency to perspire; pulse was slow, feeble and wiry, about 71 i hid taste in mouth like carbonate of soda ; vertigo, and belching of wind, attended with feeling of coldness in lumbar region. About 3 p.m. these symptoms had all disappeared, leaving tired and aching sensation in legs and arms, and slight neuralgic pains in 1. side of head. Bj 1 1 p.m. these symptoms began rapidly to disappear ; pulse and tempe> rature became normal. Slept well during n. 2nd d. — At 7 a.m. puUe

mp. normal; experienced slight giddiness in head on rising, with creeping sensation in backs of legs and soles of feet, and aching in lumbar vertebrae. 12 m., these symptoms had entirely passed off, and he felt in his normal condition. The symptoms above referred to were attended with feeling of emptiness at pit of stomach.

b. After an interval of a few d. took similar powder at 7 a.m. Temp. 9&^°, pulse 71. 10 a.m., felt slight chill, attended with trembling of lower extremities, and nausea. 12 m., felt sinking at pit of stomach with inclination to vomit, which soon passed oF. 4 p.m., had cold perspiration in umbilical and lumbar region. 8, temp. 98^°, pulse quick and wiry ; slight headache and nausea, with inclination to sleep. II p.m., went to bed, and slept very uneasily through n. till about 3 a.m., from then till 7 a.m. slept well. He then got up, feeling a little giddy, which soon passed ofF; had no other symptoms during d., except slight tremor in legs after walking \h. 8 p.m., temp. 99^^*; pulse 80, strong. 10.30, went to bed, with no symptoms to note. 3rd d. — Temp, and pulse normal. No symptoms to report. {Trans, of Horn. Med. Soc. of Pennsylvania^ 1889, p. 199.)

  1. a. Frederick VAN GuNTEN,jr.,sBt. 21, single, medical student; height, 5 feet 'j\ inches ; weight, 140 pounds ; has acquired catarrh of nasal mucous membrane, particularly on 1. side, no hereditary tendencies, temp, bilious; of stimulants takes coffee only; normal pulse, lying down 76, sitting 80, standing 84 ; normal respiration 18 ; normal temperature, m. 98°, e. 98*6°; urine normal ; stools usually regular, ist d. — At 8 a.m. took a i-gr. powder of 3X trit. No symptoms. At 11 a.m. took another powder. 11.20, passed a rather soft but wellformed stool, preceded by a little flatus. li'35, beginning of dulness in head. 12.30 p.m., dulness continues, 1.37, had a small stool, well-formed, and again preceded by a little flatus. 2.55, a tickling in throat, giving rise to a dry cough — the more he coughs the worse the tickling becomes. 3.5, dull pains in r. chest. 3.15, tickling still continues } brain seems to be clouded, so that it seems hard to keep mind on what is read. 4, tickling continues. 4.5, passed a stool much smaller than last, and not so much flatus. 5.30, took another powder. No symptoms.

b. Same, after an interval of 4 d., at 1 1 a.m. took a powder. No symptoms, r p.m. repeated dose. 6.25, passed a small well-formed stool with little flatus. 2nd d. — At 8.30 and 1 1.30 a.m. took a powder. 12.35 p.m. had a stool, but with little flatus. 3.30, took another powder. 6.30, passed another well-formed brown stool, with a good deal of flatus. 8.15, peculiar tingling on r. side of face, extending from zygoma to top of vertex ; the skin (in the same region) also feels tense, 3rd d, — Passed a somewhat restless n., having awakened once or twice, feeling as though he could not get rested ; this m. feels dull, and does not seem disposed to do anything. At 8.40 a.m. constant tickling of nasal mucous membrane, causing constant ineffectual desire to sneeze ; tickling lasted some time. Skin is very dry ; and scattered over face can be seen patches where it is scaling, giving appearance of whitish spots. 10.15, took a powder. At varying intervals experienced dull, lancinating pains in r. vertex ; during course of m. passed con-

siderablc flatus. 3.15, took another powder. 6.20 p.m., pjssed 1 medium stool, well-formed, and with flatus.

c. Same, after another 4 d., at 9 a.m. took 3 gr. During d. h»d several ineffectual efforts to stool, daily passage in m, having been very small. 10.45 P-iOm <1u'1 lancinating pains in r. groin, worse from walking. 2nd d. — At 10 a.m. took 3 gr. Felt dull all d., did not have animation enough to do anything. 2 p.m., repeated dose. 3.15, tingling in region of I. nipple; constipation continues, having had several ineffectual efforts to stool ; during d. there was clear discharge of mucus from nasal passages. 7, repeated dose. No symptoms. 3rd d. — At 9.15 a.m. took another gr. No symptoms. Bowels are a little better to-day, but stool was voided with difficulty, and not large enough for the amount of food eaten. [Ibid.)

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