Magnesium sulphuricum
Richard Hughes & Jabez P. Dake द्वारा — A Cyclopaedia of Drug Pathogenesy
Volume III — Main text
Hagneflla sulphurica. — Magnesic sulphate, MgS0^.7H30. Epsom salts, I. Frm/ingT. — 1. Nenning. (The usual absence of information, but sec vol. i, p. 30). Soon flow of water into mouth, with loathing and nausea j bitter eructation and la^te of food eaten previous d. fiorborygmus with discharge of flatus. After $ m. burning in middle of chest. — ist d. Some painful tearings from I. lower jaw up into head, p.m. Obtuse stitches In r. side of head. Tearing in 1. temple ftc^ quently. Conmsed pain and hilnesa in forehead. Pain like knife-thru^ts in head, m., wone at i p.m. j the pain In temples, forehead, and nape lasts till midnight and goes off towards m. Obtuse shooting deep in 1. car, 10 a.m. Croaking in 1. ear like frogs, when sitting, for 1 m. Loud intermittent noise in I. ear. Sometimes singing, sometimes rushing like water in I, ear. Tearing in r. facial bones, 3 p.m. Eructa. tion, with ta%te or hard-boilrd e^gs, frcquenrly. Severe stitches in L hypochondrtum for i h., after lying down e., relieved by pressure on head. Shooting bcnind lower 1. ribs when sitting. After rumbling in bowels from noon till c. 5 diarrhccic stools. First flatulent distension, discharge of foetid flatus, rumbling in bowels, then purging. Urine increased. Great heaviness of head during menses. Short cough, witn
y-t--- I -.i- (■T'>rr''i:i !:c- ;;i -iirv !! "'Tiiij; i:i l.i-t r. t:i;-t- ri!»N. Pre->ive pain In i;.. il; <-. t. l,:i!!i- : i>. 1 <. .iv ii,, ii. ln\< r viirLuv nt 1. upper anil. Violent tcdn:.j; in ',. i-i-'. i%':;:i I'lj;!"..., ii ' t'i. ;i:.-I:r ii \t .I. Furinit-.irlon in I. finjjer-t:p''. I». . ! •■ .!;:,.. I., '".i! l-i,!\ i- i a ,i -.r.i-< w.i.- 'iiip;-iit!:iij;. In>uj'era!»!tf irow-.;:.c-" '■■■-■ I- i < . (. il ;; - .i.. A., n:'. r..t -i y.v.t. — iv.A A. t.'ln-tTtul liiifTimir, i-onttirci •.'■;' .':. ',: :.■■.'>'':>■ :-. ;\r.. . r . i i !ir\ !ii >-; , \ « :\ i;iM»my. th::.k^ ^omc mi«.:on'jr.r i- •;■.!! :■- !,\ t ■;■■ t . li.v til. A- i: i.-i i ._.ii' 1:; ii< r m ti 1 ; whdi •ijiinT.injj '•e." ^tr^Kiir 1 J ■ j. ■ 1 1.'. I.-I. J- 1- iji.i i.t [•: « Ki!i., :n t. :ii<ir:.il < .iiijinis tnr .J li. Ji-rkiiii; j>arn in jn I.; . : ",« : --t, "•' p.m. K-m.,!!!.-- ■ "! i'M.^uc .itti r .liriinT tiii t. LiMihin^ ot all toi^i. ]• I !■ I,; i!';.t\ I :•.( '.tf.iTiN. «itli .ni'in \n. Attn -'"'ii .it 6 p.m. Minn- prif'k:ii^ ;iriJ m i.- ;,\ , t'.- ;i pt;!i i:. I'n'ii luj - jit "im! i-im-. )>'>*t stn.il, w ith i>un;:n« in I '■ '.- :: J- tM .1, ii.u-t I .'!■ 'I , : .; tinu- .ii n. tn Miin.i:c. I 'line i;rccr.:vh, J»-::
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:.":ii ", 1" 4 ;-.M.. K:- I'Uin !'\ * iii.!!. -.ij,!!;. i. .ii.il m. Tcirinj; in eye«. n'tth dim v-i'M., in. I'ii'i-t i»i5 li^ir.j; in. I iiiinI i-. i;:ir:ii.; ini-nH". Knictatioii, wiih vi:my t.i-ir. IK tt liiiK!... iiiiii-t'v. itiirilin;; in ilu'>t uiiilii •.iiTniini. rrtinbiing ot' hands I I i;'i;. Ml I. iii}i. K:.,"'! in lud, m. 4tli d, ^.'t■l^■^■l:u^lu■^•.. A"- it not iij;ht in her t:i!.!, - -t! i!..' ;■.■■. jil' ar.Mird. I'Mi'.t all d.»!in:n.; ^K■n■•c^. PiCN»-urc in chc-! at I,., I-.!-.- i !'•. 1 \j-t tiiT iti'-n "t \i-i'd ii; ;< :is, ; .i.tn. P.iin in ccn icil Vcrtcbrir liice t I. !-.■., w :ri; ..,1 .It ii; di rr.i -s \\n n I'-'n lud, "o iji.it '.hr cuiinot He on it, rt-licvcd hy u I k-:i.. sl.tt 'III.,; Ill r. .!!.■! (iiiii-j, i:. I. !ii_.; loi-. Svm at, nu, attiT uaking. — 5ih d. I'l i.M. I.- it,,; il. I, (niuiij a- ir ii wvw t<.rri!ily tni-t(«l, in. Kiui'taiioiiv like rotten < . ..-, ii:. Atiii -n)'}!'!.; <pn iniik pin Ii:ti_. .iii.I iommnti.m in IhiIv as t'nmi a purgative. ':..iii.' !;i !'.:i..; "it in* k. .irv r winli *iii.!i p.ipuli.'"- appi-.ir. On waking ni. back
■ .- !'!•.. :m-i|. 1,i,:i .iini i^ .i-I ■ p "n "ikii;:: in. riitiative pain with ^h»«itin^ in ( .1 ,...\ .i: .. ",;i . Dit tin-'it "■ .i.iiT..,-. I i...!i:.: •■» .ii;d thii'-i nn v\akini;, ni. — 6ih d. M ,! :i. i imir I... .11 toft i.i.id. p.ni. t..! f. 1 1 .mi,., in bat k between ^hoiildeis 'rom I iili.i iir riiiw ii.i-, ini-t ;.-,ii ;jp t'l ;.<t|..li.t. Du.iniv nt' tea-ts and bjll>. — 7th d. ."^rii.il 1 iiiii-t-. ">' .1 :» « h.iid imnp'- 1 vp- !1. .M\itli nun It Inrciiij;, pit ceded by pricking
■ r '. t I.. I'. I; .iMif I ti. il li'tit'.ti i.r..!..; ai.il ■traiiiin.',, t'ril!ti«i,il in -J h. by copious, •; < .1- < th 15 I- .1-. ■•m-i I*!::.' ii.i ' 1^:1. Sti. d. Iies>.i\f pain in both vides ot 1, . ; ;.. ,i:ii;i\ I i.i p:-!'!:!.; 1:1 i. '-.! n" ;:'.i'l «liei. ua.kin;^ in open air. Uicera I.'. , .T, ;i. <i .t I ii. .- ..I i,i,iit;.l. 1 ; I'l! , ti'ntii.ui.c 111 bide. Foul dianhiL'ic ••..' , ■-• ;th 'il :'•. ( !■ .11 "(T'l ilii'p- II. 'Ill iiii-i, «iilitnii enrwa. Fiuent cory/a l^::il ,>> o; ^n.. i. :>•: ?. d. Hiium.j .11;. I i.ii<ia(i\t- p.iin lu-tuttn shoulder^, with : . . r ,, "' .1 li-iii; il.>if a- I-,, .tv 1 (j-i, «>i, .id. unit o! wliieli shv cannot lie on it, I !i ■■.■ ■! ' V 11. i'l' I . , ! . I i.il.v in '■)■ n .tir. t,!!i d. Vti'i^i and weight in head ,,:■■ r .1,- :.• :, 1 ;. : i i . J- ;- .j: rt v ■:,-. t\ cuutat-.-n. N.oi'ea and vomiting n. and ji;. I ; I.- ".n i' !" *li iI- u !i .,'..1.-, »": -' ,1. r., i- x%!ii n -tn-am ot urine is suddenly
■ '..;.■■.!: i.r. v;,ii!i';. . -!i i',,iii u 1'. t- ii' ;; a-- il wniil burst. Frequent sneezing, V i!ii :- hi;.; c.t « i.i/ i. lJi\ 1 if.:.;!!, \MMi biinin.. ti.'iii iar\ nx to serobieulus cordis, all .1. I'l: -v.ir AV.A bt.iiiii;, ill u|i.-i (!;. ^t ir'.iii butlt "-iiiis, d\spii.r.i, when writing.— 1 '". il li.'>:'.'i;,. 'ip I.r v 1*. 1 t"i ; i:. .itu 1 t .:i:... pi't it.. vs. ]-'rt«jtiint empty ciuc- ( .!>.•:.-. Vi.il' III - 11 r li p i'!i I- 1* '»: i- ■' .r •! .i- v. i,. n -hv ha^ the nu-hse>, also p;:in i. .. .. :■ ..:.si-.li II -It;!!... ,1- .; t .i;.i ". .;-.;-n -ibv w.i.ksnu. "hen -he stands thigh": .1 .-. .il 1 .ii'i" ■!- ^"''1 't"i>. •"! -cvi : I. 't . p' n ■!; .1 b\ li.ird st..i>I with prtssing. Two , .j'i'.i • t...il i:i i.ip «! ^'.ac '>-ni,. M. '.-.', ihat li .d 1 1 a eil nn!\ 14 d., letiirncd, the .iiM l;.ii ..I Mill k, I'i.ick, Tii'.rL- mpi.';.- ill .1. iiMLi!. I- im nt mrv/.i, with pain in chest a: ■! I ■". .)■, Ml' I \pi (i.'iatinii. O:, \ ik-n- in. \t\ r iti.,uii:i; diy rough, relieved on
■ti;n.. !.p. L1..1 (. tini;,,li, with '■I- ti!,::. !i: u.lhiji t'tr 2 II. iiihil. I\t '.i-i:, 1 1<'--, ri:ti'>;r. ^:.alp stitches in head, I.- ;■ ti.d il.' i<. a.m. On luirsi ■.• li a>l tn 1. ubfi-i nI.n !i i:i r. sj.Il ot head, on rising ni. li.iii.Ir.;; i-i lip- wiili diy:: '»■, 1. Jhii^t. Ii-.'i-n at 1 p.m. Hollow bass \ M,r. ■■■I ; .1. A ■. I 111 1 K.i ,li .1. 1 in,. ^, till c fti/.i ■!,* u 1 ' ■. Nii.up sliontln^ in sec(.md p'.ai.iiix (j! r. ttiuinls ill lit-, w lull Willi).:; >.i(i.il aril ':.i.,}i paiii" tinlnteirupCcdly
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for » n. L. foot goes to sleep m. in bed. Sweat several muming«. — Mlh d. Head as if screwed in, on moving head in bed, e., and on moving eyes. On moving head brain feels loose. Anorexia for 1 d., diAtastc for meat, feels very ill. Stream of urine stops, then urine comes by drops, with burning at orifice of urethra. When coughing and speaking pain in posterior nares as if air were forced through them. Mucn mucu.-i in no%c. Great sorcne:^ in interior of chest when coughing, like burning, feeUasif sheshoutd cough up a piece of lungs. Tearing in bone of r. thigh. Sleeps badly and 1% restless. Sometimes hot, sometimes shivering, face sometimes red, sometime* pale. — 13th d. Ou waking rn,, anxiety as if conscicncc.struck. Dry cough in bed, e. Great weakness of legs. A %mall red tetter on r. upper arm and one on forearm, itching much since 8 d. — ijlh d. Soft stool, followed by tenesmus. Quivering between I. thumb and index. Throbbing in whole r. index like a whitlow, 5 m. Dreams of being injured by a. horse and ot wandering in a wood. — 18th d. Pressure on both sides of root of nose. Stitches from buth sides of chest towards one another on coming from open air into room. — aist d. Pain in occiput from carrying a weight on shoulders. — aind d. Photophobia with lachrymation. As if a ball lay on I. eye. Fmjucnt !>hooling under 1. car. Prcssiirr in chest, with tickling irritaiiun in larynx, a teeling as if lung were too large, in bed m., relieveil by getting up. Feels hot when lying. — a^rii d. Violent shoolmg in both tcmp]e<. for 1 n. Prtrs^ive pain as if a hard ball lay on upper orbital borticr. Frequent rigor over back, c. — N9 thru pnjcn. Unusually cheerKil, as if somewhat intoxicated. Extremely sad, lachrymose, thinks something bad is going to happen. Cross, disinclined to talk, p.m. Lazy, tired, sleepy, unable to work. Excited, sensitive, discontented. Weariness of legs, malaise, faintness, extremely anxious, thinks she must die, with earthy complexion. Stupid in head, a-^ though her mind was going. Vertigo as though she would tall forwards during and after dinner, for | h. Giddy and confusi-d, Ixittcr in open air. Vertigo e,, eyes close but not sleepy. On waking m. weight and dazedness, goes off on rising. Headache, confused as if bound or sereweil up. with heat and sweat. At every step painful rumbling in head !or \ h. after dinner. Brain moves when she rooves. Fiequent beating and hammeringas of a clock, first in forehead then in whole head, p.m. and e. Prcssive pain in occiput, e., goes off in open air. Prcssive pain from both sides of occiput. Boring pam in I. side of bead, with internal heat, p.m. Compressive hradachc from both side*, with heat of head and red face. Heat in crown and pain as if hair was pulled. Boring in r. side of crown, followed hy stupid feeling, a.m. Freijuent painful tearing on crown. Pricking in both temples, a.m. Tearing in 1. temple when spinning, p,m. On rising up from stooping feeling as if something pressed forwards in forehead, like congestion. Great sensitiveneiis in occiput, and on stooping feeling as if something fell forwards in forehead, worst when lying, coughing shakes him. Weight in forehead with heat in head, and feeling as if all would come out at forehead on rising up from stooping. Shattered pain in forehead, a.m. Tearing in forehead, then in whole head, better in open air, P^es^ing.tearing in forehead at 6 p.m. Painful buring-in above 1. eye^ in bed, e., for 1 h., then stupid feeling in head. Frequent darts as with an awl above I. orbit. Dimness o^ eyes with drowMnevL Eyes bum all d. Pricking a& with needles in eyei all d. On turning eyes to r. or I. violent pain in r. eye as though it would come out of orbit. Shooting in 1. ear when standing. Painful boring in I. ear. Ulcerative pain on r. side of none when pn»Aed. Pain when couched on r. ala nasi. Repeated epistaxis, also at 1 a.m. with relief to headache. Epl<uxis without relief to headache. Tearing in l.xygoma, which remains sensitive for a long time, also at 1 a.m. A pus-tule with tenMve pain behind 1. angle of jaw. Papules on r. side o\ chin and 1. ^ide of no^e, which iich when they coramrncc ; they disappear after id. A papule under r. angle of mouth, burning when touched. Teeth ache on coming into room from open air for \ h.,aIso in e. when lying down, aggravated by warm and cold things, and by contact of tood. Slight darting in 1. hollow upper molar, c. Throbbing in 1. molar, with heat of head. A blister with cutting pains on {.border of tongue. Often phlegm in throat which he cannot bring up or do^vn. Frequent hawking of tasteless mucus, m. Sour mucous expectoration, m. and during d. Constant yawning. Dryness and pains in throat. Shooting pain in oesophagus, worst when swallowing, n. Burning and shooting deep in throat, wortt when swallowing. Throat and mouth very dry, but with bitter. sweet twte, m. Bitter taste on waiting, m. Bitter taste, anorexia, prtNSurc in stomach, distended abdumen, itching 00 back. No appetite. Loaihiug at all food, even wb«i thinking of it, till
e. Water nwn from stomach into mouth frequently, with loathing at all food. At n. loathing and nausea, restless tossing about. Vomiting, p.m., finil of food, then of mucus. Trembling in stomach, general weakness, then belching of water, with nausea. Cold and stric at stomach, in bed, m. Stomach feels deranged. PrcMure in scrobiculus cordis, which is tender externally. Boring stitches externally in epigastrium, m. Shooting in I. hypochundrium, c., going off" when lying on back. Pain in belly, scrobiculus cordis, and chest. A kind of shooting in whole belly, a.m. Violent shooting about navel, increased by movement. During dinner pinching in belly with call to ^tuol. Abdomen tense and hard. Flatulent d stension, e., dia. rharijc of Aaius ni. Forcing in both iliac regions, and pain in sacrum as (rom flatulence, followed by hard stool. Nipping externally down to iliac region, p.m. and e. Itching in 1. groin. Alternately hard and s-oit stools. Urine xcanty. After micturition shooting in orifice of ureihia. Erections without seiual desire. Frctjucnt shooting in penis when ^itting and walking. Menses 7 d. too soon but scanty. Menses » d. too soon. Menses more copious than usua:, especially the 1st d. Bloody discharge from vagina not at menstrual period. Menses last only 1 d., cease 1 d., and return tor 1 d. Leucorrhoea of thick consistence, as copious as menstrual flux, with paralysed pain in sacrum and thighs. Acrid Icucorrhcea. Boring in 1. nostril as in coryia. Severe coryxa with stoppage of 1. nostril. Stuffed coryzi on rising m., gets loose p.m. Fluent coryza with noarse voice. Cough in m. with little expectoration, but with sore pain as if cut to pieces in chest. Pressure in chest with dyspnfra for 1^ h. Pressure on lower pan of chest as from a sveight, with short breath. Oppression of chest with burning there when walking. Fine shooting from 1. axilla to chest, transient. Obtuse shooting under r. breast over scrobiculus cordis, on rising from stooping, a.m. Some fine sittches here and there tn chen. Bunting and itclitng on back, as trom lice, p.m. and e. As if beaten betwixt shoulders all d. Tension and shooting between shuultiers and in nape. Tension in tendons ot r. side of nape. Tension in nape and betwixt shoulders on rising, m. Thrice twitching in arms. Tearing in whole r. arm. Frequent tearing in 1. shoulder wlun at rest, p.m. Tearing in posterior aspect of upper arm, in bed, m., relieved by Jetting up. Papules on inner a^pect of forearm after itcbmg. Tearing in tendons of I, foiTinn, 1 1 a.m. Painful tearing on I. wria.joint from noon till e., then great lendriness of the part. Itching in r palm. Drawing in 1. hand, the fingers drawn inwards. Ulcerative pain in ball of I. thumb when moved and pressed. Pricking in tip of r. thumb after dinner. Tearing in finger-tips uf both hands, n. Noon, pain in thigh. Bruised pain in 1. natis, wor^t when walking. Tearing in posterior Kurface of r. hip, ajn. Tearing in both legs down to foot and weakness in r. thigh. Tearing in I, knee when spinning, it cracks when extended. Tension in r. hou^ when nalking. Cracking m ligaments over heel. Transient tearii^g-shooiing in ball of I. f<iot,nuun. Itching in r. toes. Pricking in I. big toe after dinner. Tearing in I. toes, which coniiact, for a m. Extreme prostration, staggers when walking. Trembling jll over and weary in legs, and small itching papules all over body. Hard itching pimples k\ il stung by nettles, which burn after scratching and go off after S4 h, I'lmtplaitis all n. of violent belly-ache, for which she cannot sleep j on rising, m,, quite inconsolable. Starts frequently at n., but does not quite awake. Cannot sUcp at n. on account of violent pains in head and abdomen, weariness of feet and tearing in sacrum, on account of which she cannot lie on back. Bruificd feeling prevriiiing sleep ni n. Lung of fallmg asleep, frequent waking, many dreams, of weddings, country matters, 5cc. Gay dreams. Dreams that her dead mother appeared. Anxious dreams, that she was pursued and shot at by soldiers ; she w.ikcs in a fright, and on falling asleep again dreams that she fell into the water. Dreams ot the death ol his lather. Drtuns that she has to go to the theatre, but cannot get dresaed in time. Dreams that the next house is in flames. Dreams of danger from hones. Urrani« th.-»t \hc found a dead child in a churchyard. Dreams that she saw yellow mire, which diNgu^lnl her. In c, chilly, which goes off after lying down i on waking m. luthed tit sweat and thirsty. Shivettng witti watering of eyes, coryza, and hcaTinrss itf head. Chilly all n. till 10 a.m., it gets less after 9 a.m., thirst a.m., must go to Ind at noon.at 3 p.m. perspiration. Rigor during the headache. Rigor .it 9 p.m., which goes off on lying down, afterwards thirst. Transient heat In head coming up fiom chest, with sweat m upper part of bo<iy, later again chilly, .ind so on alternately lili r. Ou rising up in bed neat for a few in., venigo and sweat on forehead with
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red face. Heat all over body for houn, p.m. After midnight wakes fretjuentljr with sweat. After midnight swear and thirst, but at same time chilliness. Chilliness wiih shivering from 7.30 p.m., cannot get warm in b«d for i h., feet especially cold, then increasad heat towards m., tweat, no thint. Chilly and hot alternately at n., next n. onU chilliness. Though she feels hot, feet arc cold all d. Heal of head, coIdne« of rest of body, better p.m. (Better in open air). {Annal. J. A»w. KHmkt iv, 466.)
I. Dec. 7th, 7 a.m., Mag. sul. i, 1 gr. Powder tastes bitter. — 8th, 7 a.m., 4 gr. No stool. Disagreeable heavy feeling in hypogastrium and nen<>itivene!i!> of groinS| relieved by discharge of flatus p.m. — 9th. Sleep disturbed by cough, caused by tickling in back of throat. Tickling continues in m. from adherent viscid mucui. I a.ra., 8 gr. Noon, the scraping-lickling irritation in throat gone, no stool. 4 p.m. till 8 p.m., tensive heavy feeling in hypogastrium with confusion of head, which went off after a difficult loose stool with great straining, but the confusion of head then increased to pressive headache in 1. tuber frontale. There came on a feeling of raalaise, pro*«tration of strength, with dry heat of skin, and drawing pains in L tibia and 1. shoulder. — loth. Sleep disturbed by frequent waking. Confusion of head on rising, lasting 1 h. 8 a.m., 11 gr. Nuon, a soft unsatit^tactory stool followed by liquid fieces. From noon till e. 4 liquid copious stools in rapid succession, after the last stool at 11 p.m. slight pain in umbilical region. — nth. A.m., 2 liquid painless stools, some coryza, and sore pain in upper Tip lielow no^e. P.m., much xudible rumbling in belly as though di.irrhcra would come on. Towards c. more naul secretion, hoame voice, irritation causing short cough, sometimes with expectoration of viscid mucus, which seera.s to come from posterior nares into pharynx. 9 p.m., feeling of dry heat, confusion of head, slight drawing in limbs, prostration, disinclination for work, wearinesc. — nth. No sleep till after midnight, after that disturbed «leep, frequent waking. Noon, no stool. E., upper lip under nose red and tense, viscid mucus from nuse. — 13th. Slept well. Noon, no stool. P.m., confusion of head with pncssive frontal pain, flatulent distension oi abdomen, heat of face. 8 p.m., general malaise, rigor with cold hands and feet, must go to bed. After 9 p.m. the chill gradually went off, then came on fluent coryza and dry heat with great thirst. Could not >leep on account of internal uneasiness, though he was very tired and prostrated. After midnight, perspiration with relief to other symptoms.. Towards m. fell into restless sleep, disturbed by many dreams. — 14th. In forenoon felt ill, but had only a little cough caused by irritation in fauces. Had an unsatisfactory soft stool. Appetite diminished, tongue slightly furred. Dislike* tobacco. — 15th, Slept well though he dreamt much. Noon, nostool, tongue furred, little appetite, no desire to smuke. Better in open air, 5 p.m., some confusion of head, full feeling in abdomen, frequent Irritation to cough. 7 p.m., rigor very severe, had to go to bed. After 1 h. heat with cold feet for a considerable time, great thirst, confusion of head, frequent irritation to cough and fluent coryxa. The heat lasted till midnight with great drowsiness but inability to sleep, then sweat came on, during which he fell asleep. — 16th. All d. confusion of head, furred tongue, little appetite, dislikes tobacco, full feeling in abdomen, no stool, copious red sediment in urine, coryza, cough shaking chest and head, bruised pains in all limbs, disinclinatiun for all work, drowMness. Took nux v, 3. — i7lh. Slept well. 8 p.m., a moderate rigor lasting | h., followed by heal lasting bcvcral h. and ending in profuse sweat. Took during heal another dose of nux v. 3, — i8th. Sleep with confused dreams. Copious discharge of urine, m., the urine was bright yellow, soon became turbid, and had a copious red sediment. During d. frequent urging to stool, but nothing came. Furred tongue, bad appctiie, dislike to tobacco, abdomen distended but soft and painless. Coryxa and cough troublesome, disinclination for work,^i9th. Slept quietly. A.m., an insufficient soft stool passed with straining, followed p.m. by a copioiis evacuation. Tuiigue cleaner, appetite still poor, diitlike (o tobacco. —xoth. Slept well and perspired a little. Normal stool, m. Had to go a journey during which he was very hungry, and ale well. (Hencke, N. Archiv, lii, 185.)
II. Poitomifigi. — I. A boy, ast. 10, took Jij panly dissolved, partly mixed in a teacupful of water, and had hardly swallowed it bt;forc he was observed to stagger and become unwell. When the surgeon saw him, \ h. after, the pulse was imperceptible, the breathing slow and difficult, the whole frame in a stale of extreme dcoility, and in 10 m, more the child died without any other symptoms uf note, and
in particular without any vomiting. On the most careful inspection of the bod/i no morbid appearance whatsoever could be found in any part of it. (CIIRISTISON, 9p» at.)
a. An old man dranic several pint< of beer, which, it was afterwards proved, had been drugged with magn. sulph. He was seized with violent purging, and died within 48 h. On P.M. examination the lining membrane of the alimentary canal was found to be inflamed. (Taylor, op. cit.)
- Giacomini saw ^ij taken ac a single dose without producing any evacuation but chilliness instead with paleness, inability to move, trembling of the limb?<, and repeated syncope. In another case the dose was ^is^ but the same general symptoms occurred, and vomiting likewise. (Stille, op. at.)
III. ExpirimfnU on ammaU. — 1. Moreau's experiments {Arch. Gen, di MfJ., J870, August, p. 254) were made by opening the abdomen of an animal, and tying four ligatures tightly round the small intestine a few inches apart from each other, so as to isolate three portions of intestine. Magn. sulph. was then injected by means of a hypodermic syringe into the middle part, and the intestine being then returned into the abdominal cavity the wound in the abdominal panetcs was scvrn up. A few h. afterwards the animal was kilted, and on examinatian the middle portion was found full of fluid, while the portion on each side was completely empty. Thew experiments have been confirmed by Vulpian {Bull. Gen. de TAr-r., Ixxxiv, 5*1). The fluid contained in the intestine appears to be a secretion, and not a transudation, for it does not contain a» much albumen at a transudate woukl do. (Bruntom, Prmct^^ »»» 3+5—350)