Sulphur iodatum

Volume IV — Main text

Sulphur iodatiun, iodide of sulphur, Sjlj. V

1. Provirtgs. — I. Some years ago 1 happened to take 10 dr. of linct. of iodine. It was soon followed by symptoms of influenza, which I did not at the time attribute to the action of the drug. Some d. later, however, on repeating the dose, the same symptoms recurred — coryza, headache, febrile excitement, difficulty in expanding chest in inspiration, with prostration of strength. Some years after, I took 2 — 3 gr. of an iodide of sulphur, roughly prepared by myself, and similar symptoms occurred. This led to the proving whose details I subjoin. (Keuall, Monthly Horn. Rtv.^ ii, 154.)

2. a. A. J. P — , dark hair, thin delicate constitution, pale complexion, rather sensitive to medicinal influence. "April ftth, 1850,! was employed in preparing the i, trit., and during the process 1 felt a boring pain, as if at the heart, and some dyspnoea. The same e. symptoms of catarrh set in ; I felt faint and sick ; sides of head ached, with sensation as if head were pressed in a vice. Next m. I had in addition burning tickling pain in r. nostril every time the |>ocket handkerchief was used ; at the same time I perceived a strong odour of iodine. I had also sense of dryness in trachea; thick hard clots of mucus collected about top of windpipe, difficult to detach, causing much tickling and irritation of larynx, with cough. Headache continued. On the 8th I prepared^ the 2x, and on the 9th the 3X trit. My symptoms were now wor^e. ^ had palpitation of heart ; felt sleepy in daytime and restless at n. ; bowels were constipated, eyes dim, lids heavy j there was throbbing of temples, shooting pain on vertex, constant disposition to swallow saliva — throat and gullet being parched (the doing so did not allay the dryness) ; felt thirsty and feverish ; pain under I. shoulder \ inclination to take deep inspirations and to expand chest ; ardor urinx ; thick green mucus formed in nostrils ; pustule on upper lip ; erythema on chuu Odour of iodine was still present. The above symptoms were vefll severe for 4 d,, but gradually decreased from the 5th d. till by tW 14th — i6th they had disappeared. (On the 5th d., after smelling the I, trit., a burning sensation was immediately felt in the nostrils, with a very strong odour of iodine. This lasted \ h., and left dull heaidacbc over eyes and at vertex. Three weeks afterwards I smelt at the bottle containing the 4th dil., and a recurrence of the feelings in throat head ensued.) *' [Ibid.)

h. Mr. P — subsequently wrote out his symptoms in fuller d and schematic order, as follows.

Sleep. — Drowsy in daytime ; unrefreshed by sleep at n. } confu: dreams ; waking in fright ; sleeping with mouth open.

Fever. — Dry heat ; thirst ; occasional chills.

Morale. — Apathy and inaptitude for business; dread of exertion ; unsteadiness of ideas ; anxious and doubtful.

Head. — Headache as if head were compressed in a vice at sid

at sideaj.

toreness of vertex ; shooting and throbbing of temples when stooping ; firootal headache; soreness of scalp j hair feels as if erect; head feels nroUeti.

^ycs.— Sight dim ; lids feel heavy ; inclination to close eyes, as if to press out tears.

Ears, — Itching, tingling, buzzing.

Nose. — Itching and soreness ; burning pain ; yellowish and green mucus secreted ; acuteness of smell ; flow of acrid serum from nostrils ; excoriation of nostrils.

Face. — £rythematous breaking out on upper lip, with yellowish pustules, painful, sore and tender, quickly disappearing in dry scales ; ™* dry, hot, and of yellowish colour.

^eeth. — Feel soft to tongue and are coated with dark fur. Mouth. — Parched ; bitter taste ; tongue dry and hard, furred at 'oot, red at point.

Appetite. — Anorexia ; desire for acids, pickles, lemonade.

Throat. — Uvula and tonsils slightly enlarged and reddened ; drawing

^'^ping sensation at back of throat ; accumulation of dark purulent

'"/'pUs in windpipe, causing continual inclination to swallow saliva,

^'which does not moisten it ; mucus removed with difficulty and by

violent hawking, coughing and straining ; throat dry and painful to

••ch, feeling as if swelled, sore in m. ; tickling in larynx. . Stomach, &c. — Soreness and sinking in epigastrium ; constipation ; ' •'Jg in rectum.

Urine. — Smell as of raspberries ; frequent micturition, especially in "*• * ardor urinae ; itching in urethra.

^ Thorax. — ^Tightness across chest ; inclination to take deep inspi- "^^on, leaving fluttering sensation ; palpitatio cordis ; sense of heat in r^^ion of heart, much worse on awaking in m., when stooping or ^*ning forward, running, or ascending stairs.

Trunk. — Pain and soreness under 1. scapula ; weakness of spinal ^column, with pain in loins as if bruised.

Legs. — Aching with feeling of weakness ; tingling in calves and %et ; soles of feet burn and ache, and are sore when standing ; weakness of knee-joints ; trembling and aching of ankle-joints. {Ibid.)

1. An elderly military officer, of somewhat shattered constitution, but remarkably sensitive to attenuated medicines, one Thursday dissolved a gr. of 3rd trit. in 3 spoonfuls of water, and took one spoonful an h. before breakfast. Singing in ears commenced 5 m. afterwards. An h. before dinner took second spoonful, and same disagreeable sensation came on, accompanied by feeling of tightness above eyes, as if a band were drawn tightly over the forehead. Both symptoms were increased on taking last dose on going to bed. Much troubled with cough during earlv part of n., with nasty taste in mouth and foetid breath. On the Saturday he dissolved 2 gr. and took it in same manner. The first spoonful produced singing in ears as before. The second did the same, with greater feeling of tightness over forehead, increasing to dull heavy pain. ** After third symptoms became much aggravated, with feeling of soreness in throat, accompanied by a whistling noise ; also sensation of heat about pit of stomach, which increased to such a

degree as to become quite painful, extending over chest, and giving me all the feelings of an attack of bronchitis, with nasty cough, expectoration, foetid breath, perspiration, &c. ; eyes also watered a great deal. In about an h. I fell asleep ; and in m. eyes were bleared, particularly 1. one. Throat still continued sore, but was relieved by expectoration.

" After the ist d.'s experiment," prover writes, " my arms became covered with an itching rash like nettle-rash. At present I feel debilitated, as if I had had influenza." {Ibid.)

1. Experiments on animals. — 3iij of freshly prepared and pulverised Suiph. iod. were given to a terrier bitch of moderate size. No vomiting was observed to follow. Next d. the animal showed no marked sign of depression, save that she refused to take her food. The whole of the 3rd d. was spent in the recumbent posture, the animal evidently labouring under great lowness of spirits ; on the 4th d. she could not support herself properly on her legs, and eyes were dry and glassy. On 5th and 6th d. voluntary power was gradually restored. On 7th, for first time since 2nd, she took some nourishment, and thenceforward improved till by 12th d. no faculty appeared to be defective. Alvine dejections during above period were few, hard, and scanty. {CooswztL, Jodine and its Compounds. 1837.)

Volume IV — Appendix

SULPHUR IODATUM. (Bee vol. iv, p. 250.)

I, 4. W.S, Mostanper, at. 24, subject to inflamed acne of face, took one dose of 6x trit. A number of symptoms followed, but record was lost, The principal objective symptom was a series of boils upon anterior part of neck and in vicinity of mouth. They persisted for a number of weeks. (Dr. J. C. Moraay’s provings, Trans. of Amer. Inst. of Hom. 1889, p- 379-)

1. R. W. Mowrcomeny, Feb. 7th, 1887, took 1 gr. of same at 8.40 a.m, 10, slight drowsiness, with sense of heat in head and face. 2 pam. feeling of oppression in vertex, lasting till 8 p.m. Frequent sneezing during later afternoon and e., with slight coryza. 10, very frequent coughing, without expectoration, 8th.—Great restlessness during n., with some sweating. gth.—Slight pain in region of r. kidney, lasting about 15 m., worse on motion, 11th.—9.45 a.m, sharp pain, beginning at elbow and extending along inner side of forearm to ends of litele and ring fingers, lasting about 10 m. It returned again at 11.0, lasting 15—20 m, but not so severe. (Ibid.)

2. E. E. Bashore, March 7th, took same at 4 p.m. During nsuing n. was restless, dreaming about a variety of things. 8th. —

Headache on rising in m. ; it was dull, head feeling thick ; worse towards dinner-time. At noon there was full sensation in head, also throbbing, as if blood was pumped up, better when head was elevated on pillows, worse on sitting up or standing, or from least motion, with 'ticking pains. Dizziness, lasting only a few moments, better in open 3'r and when lying on side; weakened memory. 6 p.m., head hot; ll^adichc just above eyes, with aching in eyes. 9, felt a little better, during n. rested pretty well. 9th. — About noon repeated chills, afterwards heat ; temp, toi's"; pulse 100: slight perspiration, lessening ^ 3 p.m. 6 p.m., temp. ior7°, with increased sweat; pulse no. ■^Uring d. had also following symptoms: Pupils dilated; aching in "''Oat, worse on any kind of swallowing, and on r. side, with dryness '.'}^ Scraping; a small red spot just behind base of tongue; r. tonsil .'SHtly inflamed, worse on external pressure; tired feeling in lower ^Os, as after long walk, aching bruised pain in them, going up limbs ^ Spinal column to lumbar vertebrje, better when moving and on .^^^Overing limbs, worse during rest; limbs felt stiff, so that he had to . ^g them along. 10th. — 8 a.m., less pain and swelling in throat, and ^* on r. side only, i ith. — Mouth sore on r. side ; diarrhoea. {Ibid.)

1. G. Rhoaos took same at 5 p.m. He had dryness of throat ^*on after taking drug, followed by soreness in e. Early in m.

pain in abdomen as though diarrhœa was coming on ; stool was soft. After 24 h. watery discharge from nose, and in 48 h. considerable phlegm in throat, expectorated easily, [Ibid,)

o. H. LiNDLEV took same March 7th at 5 p.m. About 8, noticed stitching pain in belly, such as is produced by running after drinking. About 1 1, in open air, noticed ropy phlegm, tasting salty, and constant desire to clear throat, with cough relieved almost instantly on getting into warm room. The salt-tasting phlegm appeared again next d., gradually decreasing. On 9th and loth, slight tenderness at end of nose, as from a boil, going off on nth ; on which d. and on 12th he had crampy pain in abdomen. {Ibid.)

1. H. L. Northrop took same one Monday. On following Thursday appeared papular eruption on face. Next d. came a boil on 1. side of neck just below angle of jaw, which opened about 10 d. later. Within a short time of its doing so, two others appeared near it, then others, during two weeks 14 in all. {Ibid.)

2. Jos. S. Garrison took same on Monday at 5 p.m. On Tuesday a violent attack of sneezing set in, lasting, with short intervals, for 4 d., accompanied by much running from nose, and followed by constriction of chest. {Ibid.)

3. O. H. Paxson took same at It. 15 a.m. P.m. noticed slight throbbing pain in 1. temporal region, which continued till 10 at n. {Ibid.)

4. J. B. Given took same Jan. 27th at 1 1.20 a.m. At 3.40 p.m., griping pain in bowels, just beneath umbilicus, extending downwards, with desire for stool. Cutting sensation in anus while at stool, with •ore feeling in bowels afterwards. Dull pain in bowels all afternoon,

with tendency to nausea; loss of appetite, with thirst. 28ch.— 6.30 a.m. tired languid feeling ; sleep has’ not refreshed ; tongue coated; pain gone, and more appetite. 10.30, unsettled feeling in stomach and bowels, and thirst. Dull feeling across forehead and in eyes. 2gth.—Felt a little better; bowels rather loose. 4 p.m., slight headache, and bad feeling at stomach. 30th, 31st.—Tired depressed feeling continued, with coated tongue ; and a pustule appeared on neck, soon becoming a painful boil. He continued to feel poorly in same way throughout its course, (Jbid.)

13, R, Bamey, zt. 19. Took same at 11.20 a.m., Jan. 28th, In Feb. 1st had feeling of soreness all over body, especially joints, and constipation. and.—Much the same feeling on rising, also sensation as if back would break. Could not straighten up after bending forward without this pain, especially in loins. At 11.30, feeling as if he would faint, felt so weak in head, and as though he would fall at each movement.” Bowels constipated urine orange-coloured, and Heller's test showed a trace of albumen. Constipation continued for a week more. (Jbid.)

1. H. M. Parker, Jan. 27th, 11 a.m. took same, In 15 m. slight tickling to cough lasting 4h, 28th.—Eyes injected generally inl, in r. one bright red clot opposite to ciliary vein, 6 p.m., sore throat, aggravated by empty swallowing, and better in open air; this continued all next d. 3oth.—On rising, sore throat had entirely ppeared. 3.30, violent general headache, accompanied by dizziness and nausea, continuing to 6 p.m., when it passed off on going into air. A small pustule on back of neck ; bowels constipated, stools hard and knotty. —(Jbid.)

2. C.G. Caprox, Jan, 27th, 11 a.m., took same, 11.13, slight running (sic) or warm feeling in stomach, worse near cardiac orifice ; and slight pharyngeal cough, lasting 1h. 2.15, dull frontal headache, I. side, ‘occasionally radiating to occipital region, worse on motion. 3.45, epis~ taxis, r. side—dark clotted blood—on blowing nose ; it recurred every time he did so (and only then) for 5 m, (had never had nose bleed in hislife), Post-sternal pain, of stinging type, worse at end of expiration, and slightly to I. of sternum. 6.45, cutting pain in I. groin, worse on taking a deep breath, 28th.—A stuffy cod set in, and Tasted a week,

bid.)

(WL. Buat. On Monday, took same at 5.45 p.m., and experienced an unconquerable drowsiness alle, At 6.30, when washing hands they felt numb ; 10 m. later, while sitting, same feeling in feet. During c, more or less perspiration ; great languor, and tendency to do silly things ; study impossible, can read, but cannot take in sense of words ; on falling asleep would wake with a start and feeling as if a pin was running into instep. The following Saturday m,, and for two successive Saturdays thereafter, woke with a tearing neuralgia in 1, side of face, with pains darting into eye, nose, temple, ar, and teeth ; temper very irritable with it. (Had never had neuralgia before.) (Jbid.)