Natrium bromatum

Volume I — Main text

Natrum bromatum, bromide of sodium, Na Br.

L Pravirtgs. i. During course of an c. 1 took 25 gr. on an empty stomach, in two doses of 10 and one of 5 gr., at i h. intervals. The efl'ect on pulse and temperature was negative ; upon retiring to rest as usual, I experienced a somewhat pleasant drowsy sensation and slept remarkably well, though 1 awoke several times during the n., as is customary with me. Towards m., however, I felt a numbness and tingling in both forearms and in my 1. leg, which did not entirely disappear for some h. subsequently. I ought to state that shortly after each dose 1 experienced a burning sensation at the epigastrium, which quickly passed off, (HoLUS, Pract, xi, 81.)

1. Laborde took 16 grms., and experienced thirst, salivation, great wish to sleep, stupor on waking, melancholy, vertigo — ground under his feet seemed to move, ataxia, slow pulse, loss of power of will, and insensibility of throat. (J, fh Z., Ixxxvii, 46, — Referred to ^irch. de Pk^ihl, for i8b9, but not to be found there.)

II. ExperimtMis Oft attimali, — 1. Harmailynjinouuttr n^^ LoniiLLtuit ^vitn : _ tcryol cockcr.dog ■ 50 ^j. hromidc at jiodiam, m jij witcr, into jugular* Ml ''frhosc highest mark na» jj in,, Icll directly to level, and ruiuiricti there 60 &ccoi oiscillatiom distinguishable, in i miu. after injection, column began to rise, an 1 regained former level, osi'ilJatioiis less frequent, but stronger than before opciuM-.m. 4 min. after operation, heart seemed restored* he was set louse. Had lost power of moving limbs, but retained come iousn ess, Puptl dilated, HcartS action became synchronous with respiration^ being 54 in niinntc. One h. after operation was in »same state, but gradually recovered, (GtovtR, /or. cii.)

1. A hundred gr.^ injiij water, were thrown Intojugulaj' of terrier bitch (largt and strougj. Only symptom wa§^ much quickened and excited heart. Animal m being act loose seemed Hvely and excited, \lbid,)

• For other bromides seethe substances with which the B. i» compouniled, — Kos,