Carduus marianus
Richard Hughes & Jabez P. Dake tarafından — A Cyclopaedia of Drug Pathogenesy
Volume II — Main text
Carduus Marianus, our Lady's thistle. I. Provings.-1 . a. REIL. From 1st to 5th of March, 1852, took 5 dr., from 6th to 12th, 10 dr. of tinct. 4 times daily without sensible effect. On 13th and 14th took 12 dr, in same manner. M. stool on 14th harder than usual. On 15th, 4 doses of 15 dr.; very hard evacuation at 8.45 a.m., another similar one at 6.45 p.m. On 16th, 4 doses of 20 dr. One hard stool at 9 p.m. On 17th, 4 doses of 30 dr. Some nausea after each, ending in sense of inflation of stomach, which was increased by a horseback ride p.m. No stool. On 18th, 4 doses of 40 dr. Last n. restless, with frequent waking; lying on back produced nightmare, which woke him twice. Very hard,unsatisfactory, difficult evacuation of brown knotty fæces immediately after dinner, somewhat relieving inflation,which nevertheless obliged him to draw long breaths. Slight dulness of head. On 19th, 4 doses of 50 dr. Very decided nausea after ist dose, much lessened after others by diluting them more; appetite small; urine cloudy, without sediment, golden-yellow, acid ; no stool; increasing epigastric uneasiness . b. Prepared decoction of zj of seeds to zxij of water, boiled down to zvj. On 20th, took tablespoonful 4 times, with 10 dr. of tinct. to each dose. Nausea after every dose, but somewhat slighter than yesterday; dulness of head alld., with occasional transitory headache in forehead and temples; tongue white in middle, red at tip and edges; empty eructations after food taken without desire ; no stool, but inclination for one ; urine whey-like, yellowish brown, diminished in quantity, acid. On 21st, same doses with 20 dr. of tinct. in each. Same subjective symptoms ; at 10 a.m. hard scanty stool; at 11, copious pappy one, but little coloured by bile, more of a chocolate colour, preceded by violent rumbling and colic. Urine as yesterday; reallyless; after 6-8 h. depositing sediment consist consisting chiefly of chloride ofsodium and lime. Experiments with solution of sugar and sulphuric acid gave traces of biliary colouring matter. On 22nd, the same. Restless, dreaming n.; increased nausea after doses ; loss of appetite ; feeling of inflation so strong, especially on r. side, that he expected to discover by percussion great enlargement of liver, but it was not so, though whole region was painful to pressure ; frequent urgings to deep breathing, followed by indefinable painful sensations in abdomen; every sudden and strong movement of body painful, both in chest and abdomen; stool at 8 a.m., pappy, loamy, destitute of bilious colouring; urine scanty, brownish, showing presence of biliary colouring matter as before. On 23rd, 3 similar doses with 30 dr. oftinct, in each. After 1st, violent nausea very soon, and, 10 m. later, painful retching and vomiting of acid greenish fluid; pains in stomach for 2 h. After and dose, great nausea, but no vomiting ; painful griping in stomach, and cutting here and there in bowels, with rumbling. After 3rd dose, nausea so bad he was obliged to excite vomiting to relieve it. Great debility all d.; no stool ; urine as before. On 24th, one spoonful, followed by such nausea that he concluded system was saturated with
drug, and omitted it. At6p.m. unsatisfactory, hard, loamy stool; urine as before. Sense of fulness and tension in epigastrium continued, gradually decreasing, till 28th. From 26th, stools began to be pappy as usual , and somewhat tinted with bile ; urine remained cloudy till 28th, but on that d. had lost all trace of biliary colouring matter. On 29th, quite well. ( Hom. Vierteljahschr., iii, 452.) 2. Dr. BUCHMANN, on December 4th, 1877, took from 1.45 to 2.45 p.m. 5 dr. oftinct, every 10 m. Immediately scraping in throat causing cough. After 3 m. shooting pain on a small spot of 6th 1. rib in linea axillaris, with continual drawing pain inthat line. After 10 m. drawing pain on inside of 1. scapula. After 15 m. pressive pain on a spot the size of a shilling on 1. side of nape at level of mastoid process; soon afterwards on the corresponding part of r. side. After 20 m. drawing pain through 1. pectoralis muscle and 1. intercostal muscles below axilla ; the shooting pain, which affects breathing, gradually forges forwards. After 25 m. pressure in eyeballs as ifpressed into orbits; burning in edges of upper lids. After 30m. tensive pressive pain in sagittal suture as if something contracted round skull After 35 m. transient drawing pain between navel and scrob. cordis in peritoneum from r. to l., followed by burning pain,with hot feeling in a spot the size of a hen's egg midway betwixt navel and l. inguinal region. Great discharge of flatus. After 40 m. burning pain in skin on inner side of lower half of I. forearm, also on outer aspect of 1. index. After 45 m. drawing pain in skin on outer side of 1. knee, drawing pain through r. pectoralis muscle and on inner border of r. scapula; afterwards, while driving, continued drawing pain in 1. side of thorax up to axilla ; the shooting pain only felt during expiration and deep inspiration. At 4 p.m. weariness and sleep for 10 m. 7p.m., after supper, drawing and shooting pain in region of 5th rib during expiration, burning in edges of upper eyelids. 9 p.m., to dr. Soon, scraping inthroat causing cough, tickling in mucous membrane of outer orifice of nostrils, great discharge of flatus. 11.30 p.m., waking with chilliness and urging to urinate, about 2 tablespoonfuls of urine passed; stitches after deep inspiration as before; paralytic pain in l. tibia, drawing pain in cutaneous nerves below patella on outer side of leg; tickling in 1. nostril ; very uncomfortable general feeling, with drawing pain in r. scapula and 1. side of chest ; crawling sensation as if a body the size of a pea were moving in a narrow channel on posterior side of liver from r. to l. in pit ofstomach at the level ofthe edge of the ribs, 3 times after a minute's pause, each time lasting 3 seconds; feeling of roughness and dryness in palate and fauces causing drycough, collection of fluid in nasal cavity towards external orifice.-5th, m., on waking, drawing pain in all back, watery discharge from nostrils, cough from irritation in fauces, slight burning in palate. Noon, flat taste of moderately salt soup , good taste of well salted soup, but repugnance to salted meat. 2 p.m., eructation of air with burning feeling in mouth of stomach as from acidity. 10 p.m., drawing pain in 1, side of thorax. 2 a.m., wakes with pressure in stomach, burning in eyelids and anus; drawing pain in r. upper arm and cardiac region, after passing urine burning inorifice ofurethra; 5 dr., after some moments increased burning in eyelids, several attacks of short dry cough without tickling, rheumatic drawing in 1st joint of1. 4th finger, remission of stomach-ache, pressure in precordium, burning in stomach as from acidity, coughcaused by rough feeling in fauces and œsophagus. 2.15 a.m., burning in pharynx, rheumatic drawing in first joint of r. index, burning pain in bowels in hypogastrium ; raw feeling in pharynx causing cough. 2.30 a.m. , drawing pain with burning in bladder, pressive pain on inner surface of skull at coronal suture, pressure in r. pectoralis muscle; drawing pain through bowels in hypogastrium, rough feeling in larynx causing cough, drawing pain in lumbar muscles,when lying on 1. side tension and pressure in liver.-6th, m., pressive-burning in eyelids with swelling and weight of them chiefly in 1. eye, which can only be opened with difficulty, confusionofhead with tensive pain in suture of 1. parietal bone. 4p.m., when driving, pressive pain betwixt ribs and hip on r. side of belly lasting h., drawing pain from r. scapula down back, tensive pain in r. hypochondrium. 5 p.m., weariness and sleep for some m. 7 p.m. , sudden painful cramp in muscles of r. sole flexing toes, after that has ceased great itching in sole in front ofheel ; drawing pain on outer side of r. 4th finger.- 7th, 5 p.m., drawing pain in back for h., followed by weariness. 10 p.m., 2 dr. After 3 m. drawing pains in r. deltoid and back ; burning in eyelids.-8th, 3 a.m., wakes with erection, violent rheumatic pains in r. deltoid and in muscles covering r. radius ; drawing pain all over back; great discom.
fort and stomach-ache, pressure in eyelids, especially 1., with feeling of its being swollen. 3.15 a.m., drawing pain in muscles covering 1. radius ; empty feeling in stomach, burning in anus and nostrils; pains in r. upper arm become periodically so violent that he cannot refrain from groaning; on raising r. upper arm pain in shoulder-joint. 10 a.m., for the last h. drawing pains in r. side of back from scapula to lumbar region, changing from one place to another after 1 m., also on outer border of 1. scapula and through muscles of r. or 1. radius ; pain in sole in front of heel increased by moving ankle; painless flatulent distension of ileum ; pressure and same feeling in ileum on 1. side ; pressure in nape and r. temple ; pressure in urethral part of glans; drawing pain from 1. side of chest to back, then towards 1. pectoralis muscle ; drawing pain through r. groin. 5 p.m., drawing pains in back. 6 p.m., when walking stiff feeling inknees, at patella and in tendons of hough, with paralysed feeling in legs, uncertain, staggering gait.-9th, m., pain in hip-joints spreading through nates, making rising difficult, aggravated by stooping ; drawing pain through back and from outer side of knee to external ankle ; burning in eyelids ; bruised pain in nates.- 28th, 11.30 a.m., 5 dr., 1st dil. After 3 m. burning in 1. nostril; drawing pain in back and inner border of r. scapula; cold feeling in soles; drawing pain on inner side of r. leg to internal ankle; drawing pain in 1. side of chest; burning in eyelids ; empty feeling in stomach; drawing pain in 1. scapula ; drawing pain in lambdoidal suture. After 10 m. drawing pain from 1. and r. through scrob. cordis and epigastrium ; drawing pain through 1. pectoralis muscle; hot feeling in face. 11.45 a.m., pressure in forehead and eyeballs ; drawing pain from 1. knee down leg; pain in r. concha round orifice of ear. 12 noon, cramplike drawing pain in inner side of r. hand, extending to first two joints of 4th finger; drawing pain through back and hypogastrium; rumbling in ileum. (Allg. h. Z., xcviii, 11.) 3. Mrs. BUCHMANN.-Dec. 8th, 10.30 a.m., 5 dr. tinct. After 5 m. astringent metallic taste in palate and fauces ; feeling as ifm.m. were quite smooth, as if covered with grease ; tickling sensation felt in l., then in r. nostril; continualyawning. After 10 m. drawing pain in border of ribs, with stitches when breathing there, mostlywhen expiring; pressure in forehead above eyes ; heaviness in eyelids. After 15 m. call to urinate, burning in urethra and rectum, preventing her sitting; dry feeling in palate and lips gradually going off. 4 p.m., 5 dr. After 10 m. same symptoms in buccal cavity, and also symptoms as above. 6.30 p.m., 15 dr. After 5 m. cramp pain in l. calftill 10 p.m., cramp pain in muscles about radius and in fingers of 1. hand for 10 m. After 10 m. violent pain in r. side of abdomen, increased by pressure, lasting till she went to sleep ; for hand's breadth round navel in bowels sense as if bowels moved when breathing ; weakness and ill-feeling ; burning in urethra with swollen feeling thereabout; sadness and inclination to weep ; short dry cough from irritation in pit of throat; frequent yawning, anorexia.-9th, 3 a.m., waking from pain in r. lumbar regionwith pain in urethra; feeling ofmoving ofbowels on expiration. 9 a.m., slight pain in r. side of abdomen and burning in urethra. 3.30 p.m., cramp pain in r. calf; violent drawing pain in r. deltoid and muscles of r. radius ; cramp pain in 2nd, 3rd, and 4th r. fingers ; burning about urethra compelling her toget up from seat; pain in lower part of r. heel, aggravated by treading.-22nd. Until to-day daily periodic cramp-pain in r. calf, in r. sole, and in extensor tendons of 3 middle fingers of r. hand.- 28th , 11.15 a.m., 5 dr. 1st dil. After 15 m. burning in r. nostril with watery discharge from it; drawing pain in cardiac region with tightness there on taking a deep breath ; contractive feeling above eyebrows ; burning in urethra and itching in anus ; contractive pain in vagina ; heaviness in head ; constant flow of water into mouth; rough feeling on tongue; palate feels smooth and greasy; rough feeling in fauces. ( Ibid., 19. ) 4. BUCHMANN's son, æt. 24.-Dec. 23rd, 10 a.m., 5 dr. tinct. I p.m., pressive pain in occiput. 3 p.m., the pains have come into sinciput. 4 p.m.,pains in sinciput increased; great drowsiness and bruised feeling in arms and legs for h.; tearing in 1. scapula and upper arm, tightness in l. side of chest. 4.30p.m., rigor with quickened pulse, 90. 5 p.m., increased tightness and pains in 1. side of chest, especiallywhen inspiringdeeply. 5.30 p.m., pains in 1. parietal bone; cold feeling in toes. 6 p.m. , dry feeling in larynx with irritation to cough in back of larynx. 6.30 p.m. , drawing pain in l. knee-joint with cold feeling in both knees; pain in r. instep; burning in eyeballs; short stitches behind 1. short ribs. 8 p.m., cough from irritation inback of
larynx. 9 p.m., pressive pain in r. hypochondrium; cold feeling in knees. 12, mid. night, wakes with cough from irritation at back of larynx; rigor. ( Ibid. , 20.) 5. IDA BUCHMANN, &t. 25.-Dec 7th, e., on going to bed, 10 dr. tinct. Itching on skin after lying down in bed.- 8th, 10 a.m., 20 dr. 11 a.m., flow of water into mouth. 8 p.m., loss of appetite, pressure in stomach until she fell asleep.-9th, m., occasional pressure in stomach ; anorexia.-19th. Daily attacks of pressure in stomach, appetite diminished till to-day. (Ibid., 20.) 6. MARTHA BUCHMANN, æt. 19.-Aug. 7th, 6.30 a.m., 3 dr. tinct. After 5 m. flow of saliva into mouth. 6.45 a.m., 10 dr. After 10 m. shooting in lower border of ribs anteriorly at every inspiration ; then pressive pain in scrob, cordis externally. 7 a.m., weariness and frequent yawning; burning in eyelids ; pinching pain inbowels on 1. side. 9 a.m., 20 dr. After 5 m. flow ofsaliva into mouth; when speaking and swallowing pressive pain in region of os hyoides on 1. side with feeling ofswelling there, increased by pressing on it; frequent yawning with weariness. 9.30 a.m., pressive pain in forehead and temples ; when walking pain in houghs, 1. especially. 10.30 a.m., shooting in r. side of chest anteriorly in region of 7th rib when inspiring deeply. 1 p.m., shooting pains in region of 7th rib, r. side, when stooping. 3 p.m., for 1 h. the pains have spread all over front part ofchest, and are so violent as to make movement ofarms, walking and stooping almost impossible ; frequent eructation of air with burning in œsophagus like heartburn. 10 p.m., 5 dr. No stool to-day.-8th, 7.30 a.m., 15 dr. 8.15 a.m., stitches when inspiring between linea mammalis and axillaris at r. 6th rib. Great weariness.- 13th. On Aug. 8th insufficient hard stool, no more stool for 4 d. To-day a hard difficult stool. (Ibid.) 7. FR. JUNGKLAASS , surveyor, æt. 24.-Aug. 20th, 5.15 p.m., 8 dr. tinct. Immediately great weariness. 5.45 p.m., fine stitches to r. and downwards from 1. nipple, lasting some seconds. 6.43 p.m., rigor, with feeling of a pulse in abdomen; pressive headache like commencing catarrh. 9 p.m., nausea, with flow of water into mouth ; pressure in forehead.- 21st, 11 a.m., eructation of air. 3 p.m., great weariness after dinner; pressure in stomach with eructation of air; pain in occiput; pain in r. eye. 8.40 p.m., 16 dr.-22nd. After rising great prostration in arms and legs. 10.30 a.m. , pressure in stomach with eructation of air. II a.m., pressure in hepatic region with ravenous hunger. 12 noon, when walking feeling as if there was a band round calf a hand's breadth below knee. 6 p.m., repeated eructation of air ; slight headache above eyes and pain in occiput; pulse slower by 10 beats; ineffectual urging to stool with great pressure on bladder causing the urine to dribble away.-23rd. Disinclination to get up. In forenoon confusion of head with disposition to be angry; occasionalpain inliver and sacrum.-24th, m.,32 dr. Alld. great confusion of head ; shortly before dinner empty feeling of stomach and headache, which goes off after dinner.-25th. Wakes withpain in belly near r. os ilii. 11 a.m., stitches in ileum, relievedby pressure; great forgetfulness.- 26th. Recurrence of abdominal pains while walking in open air. After drinking a glass of small beer, urgent call to stool as from diarrhea, stool of ordinary character.-Sept. 4th, 8.30 a.m., 50 dr. Soon pressive sensationas from flatulenceunder1. border of ribs, lasting 10 m., followed by same sensation on r. side, spreading thence to the r. and backwards, when the pressure on the l. side goes backwards; pressure overl. eye. 11 a.m., burning sore pain in 1. scapula when inspiring, increased by pressure andleaning. 12,noon, pressive pain in hepatic and gastric regions, increased by pressure with hands ; on 1. side of stomach shooting increased by inspiration. 7 p.m., 30 dr. When sittingdrawing pain in bladder and testicles.-5th. At n. frequent shivering. 4.45 p.m., shooting pain in belly a hand's breadth from r, hip; e., stitches in cardiac region.- 6th. Forenoon, burning pain in back. 12, noon, stitches in cardiac region. 2.15 p.m., 50 dr. Bitter taste, and feeling of scraping in œsophagus for 15 m.; drawing pain in carious tooth ; pressive pain over 1. eye ; a carious tooth aches when touched by tongue; stool lumpy and hard. 5.30 p.m., pain in occiput. 6 p.m., rheumatic pain in shoulders, spreading from neck ; pressure on back below scapula. 6.30 p.m., pressive pain in r. side of belly when the body is stretched out, with hot feeling. 7.15 p.m., constant shooting in inner border of 1. scapula. 8 p.m., pain above orbits.-7th. Waking in generalperspiration, weakness, and erection; copious flow of urine with drawing in both sides of hypogastrium. 8.35 p.m., on bending backwards shooting pain a hand's breadth above r. nipple, also when raising r. arm. 1 p.m., frontal pain before dinner, going off after eating, with pain in eyes and occiput and sweat on forehead
and back ; pressure in wrists and shoulders. 1.25 p.m., all pains except those of eye gone. Instead has pressure in temples, nausea with eructation; flow ofwater into mouth. 2.25 p.m., only pains in r. eye remain. 5.25 p.m., shooting in hepatic region with moist skin. 5.35, when urinating drawing in r. side of belly.-8th, m., 20 dr. Burning pain inthroat lasting 1 h. (Ibid., 26.) 8. LEMBKE made decoction of 2 oz. of seeds in 1 lb. ofwater and drank it, but it caused no symptoms whatever. (N. Zeitschr.f. hom. Kl., x.)