Lilium tigrinum

Volume III — Main text

I, rjpiiwi, H. K. T^ niy. Nai. Ord., SMUu*^.

1. Prwings,'--!. Dr, S. P. G&avb^ *t, 37, took — 2 h, after eating — 5 dr. of 3X dil. of tinct. of Bowcn, In about 1 4 h, felt dtdl press! ve pain in I. dde, ai»arent]y about heart ; coldness of outer I. \e%^ as though cold wind wai blowing upon it ; dulness of r. h«-ad^ increasing to sense of pressure, Indtning bead, over to h side. These sy^mptoms graduallv increased for about 6 h^ then gradujdly abated, when he feU into a sleep which continued about 4 h>, from which he was audJcolr aroused by pain in 1. side, as if beurt were violently grasped, interrupting pulsations of heart and breathing. It was relieved by rubbii^ and pressure, and grasp gradually relaxed. Tingling of Icn sec in^ and continued during 2ndd. $ heart-pain was better in m., but worse in afternoon and on lying down at n,, aggravated by stooping, leaning forwards, or bowing. After all symptoms had parsed away, took second dose, before eating. Same symptoms returticd, less marked, but of longer duration. Pain in heart continued for more than xwo week^, gradually abating, and at last felt only un bending body forwards. Urine on 2nd d. after each dose was copfuu<i und hi^h-colourcd. (Dr. W. E. Payne's provings, 7r«if. rf Amtr, imt\ 7/lLm,^ 1867,)

2. a. Dr. J. W. Sayagb took, Feb. 20th, 1867, 30 dr. of tinct. on sugar at 3.30 p.m. Pulse was then 76. 6, dull, heavy, or pretyivc^ pain in region of heart; sharp pain in both Icnces, on inside, extendiittfl towards front at point of connection of patella with rectus tcndoo^^ Pain was confined to a small spot ; he never felt anything of the kind , before. 7-30, pulse now 88, took 30 dr. mure. Both lower limli^H below knees feel dull, heavy, and full, with formication and ^hifti^^^ pains I pulsations in both feet ; slight nausea ; cardiac pain continues ; didl and occasional shooting pains across smaU of back, lasting a »hon time. Pains all seem to occupy small spots, as if produced by hard pressure with ends of fineers on parts. 9-30, pubc 88, repeated dose. Quick pain in both ring ungers and corresponding toes at s-^me time, passing off in a few seconds. ZO, moving of Hatu5 tn boweli, with rumbling and feeling of fulness ; nausea, with great desire but inability

to vomit ; bubbling sensation in r. hypochondrtum. There was aliglii pain in bowels all n., with rumbling ajid violent emission of flatus ^^ sensation as though diarrhoea was about to occur. Next m. abdomen was tender to pressure. 7.30 a.m.^ t»:)k 30 dr. more* Soon stool, dark and hard, followed by a good deal of heat in rectum and anus, with slight pains in abdomen ; weakness and pain in knees when walking, especially on ascending; dull and heavy^ with occasaon; quick, pains in lower limbs below knee j small spot on inside of thigh very painful at intervals j dull boring pain on top of L ft with inclination to vomit, and frequent luwking of mucui f great distension of bowels, with much upward and downw flatus (this is a constant effect of drug) ; heat and pressun trium. 11.45, 3^ ^^' more^ pulse 72. Constant heiv^

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cardiac region all afternoon, and pain in ankle-joints^ worse on moving. 6, sharp pains in Inside of 1. thigh, over femoral artery, about 2 in. below Poupart's ligament. 22nd. — No medicine; pain in thigh, flatulence and lameness in ankles gradually diminishing. 23rd. — No symptoms. 7.30 p.m., 30 dr. Klatulenc distension of stomach and bowels, with rumbling, returned; also heaviness in cardiac region, and palpitation when tying on 1. side in bed at n.

b. "The heart symptoms now became so troublesome that I was obliged to discontinue further use of the drug. The symptoms were always much worse at n., giving me, comparatively, but little trouble in the daytime. The heart s action was intermittent, every intermission followed by a violent throb, causing an involuntary catching of the breath ; at the same time the blood rushed up through the carotids to the head, producing great heat and a crowded feeling of head and face. These symptoms followed me for more than a month ; indeed, so constant were they that I became alarmed, fearing I might have misjudged the case, and, instead of medicinal symptoms, I was really suffering fi'om an organic disease of the heart. But a physical examination of the heart's action, by a brother physician, put my mind at rest on this point.'* (Ibid,)

3, F. G. Barker, aet. 30, took, May 9th, 1868, at 8 p.m., 6 dr. of linct.* in water. In about i h., having been reading and writing, experienced slightly confused feeling in head, with little pain. This increased after going to bed, and there were slight rushing sounds in both cars. About middle of n. woke suddenly, with coated feeling in mouth and throat, and had to rise and empty bladder (very unusual). Same thing happened again at 5.45., when also he had continued heavy feeling in head ; steady, though not severe^ pain in lumbar region \ and intermittent sharp pain across hypogastrium. Slept again till 8, when bladder had again to be relieved. 10th. — Continued lumbar pain, though sensibly growing lighter; it was occasionally transferred to between shoulders. Sharp, though not severe, pain over 1. eye almost continuously during forenoon. ii.45i lumbar and eye pain almost gone, but some still felt between shoulders ; took 8 dr. No effect, save slight increase of eye pain. 4.30, repeated dose; eye pain increased, and lumbar pain recurred ; urine remarkably clear and pale ; drowsy early in c., and could not work. nth. — Arose late, very much distressed with pain in lumbar region, which lasted through d. and did not cease till c. 12th. — At 5.40 a.m. took 8 dr. again, without effect. 13th. — At 6.30 a.m., 12 dr. In middle of forenoon, intensely sharp pain in r. side, between hip and false ribs, extending to umbilicus, and becoming a sort of colic, so severe as to render a full deep breath intolerable ; was almost obliged to stop work (type-setting). Pain lasted till a little past noon, when it stopped suddenly. (Ibid,^ 1868.) j 4. a. Miss , teacher, xt. 42 ; had not menstruated for 2 years,

but had enjoyed uninterrupted good health. Sept. 3rd, 1^67, at 8.30 a.m., took 5 dr. of tinct., and repeated same on two following d. From 6th to 15th took 10 dr. daily. Hitherto no effect. 1 6th. — At

• The tincture used jn this and the folluwing proving nas made from stalk, I'leaves, and €owcn.

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8.30 a.m. 25 dr. In 2 h. pain commenced in forehead above e^ severe for more than an h., then graduiiUy abating. 20th. — Took dr, in course of 2 h. Pain in sacrum, with sensation of weight and downward pressure in hypogastrium, which continued with some severity till 26th, worse when standing. 26th. — Took 30 dr. Discharge of bright-red blood from vagina, with dull heavy pain and ercat weakness in small of back and loins, continuing four following d. Took no more medicine, and does not report again till isth, when she felt constant nausea, with sensation as of a lump in centre of chest, which could be moved down by empty swallowing, but ascended again when effort was over. Bearing down continues, with severe pressure in rectum and at anus, and constant desire for stool, but with every effort CO evacuate the bowels, urine only was discharged. Sensation as if a hard body were pressing backwards and downwards against rectum and anus -f standing on feet aggravated, and increased desire to go to stool. (These symptoms were somewhat relieved by walking in air, and riding.) Bowels feel as if distended; trembling sensation in abdomen, with chilliness ; cold feet and hands ; loss of appetite ; aversion to coffee, nauseated on thinking of it, though it was habitual and favourite drink in m. ; frequent passing of urine in small quantities ; faint in a warm room, and on standing, with cold perspiration on back of hands and on feet ; cannot see objects distinctly j depression of spirits, constant inclination to weep, with fearfulness and apprehension of suffering from some terrible internal disease, already established ^ weakness and trembling of bowels, with loss of strength ; very sleepy at other times than usual sleeping hours. 20th. — Above symptoms having still increased, prover submitted to examination per vaginam^ when uterus was found low down, fundus tilted forwards, and os pressing backwards on rectum, allowing but difficult passage of index between. Helonias gave partial relief in I d., complete in 3 d.

h. Dec. 17th and i8th, took 15 dr. of ixdil. 3 times without effect. 19th. — Took 20 dr. at 10 and 3. In i h. after last dose, felt sharp quick pain in I. chest, with fluttering of heart. 6, sharp pain over I. eye, abating after an h., but continuing all e, 21 si. — Awoke free from pain. 9 a.m., 25 dr. Frequent attacks of palpitation ; dull pain in sacrum ; loss of appetite, aversion to bread and coffee. 22nd. — 2 p.m., 25 dr. Dull pain in forehead over eyes \ low-spirited ; aversions continue ; dull and constant pain in back, between hips, with pressing downwards at anus, which continued to 26th, not much relieved on lying down. 26th. — II a.m., 30 dr. Dull pain in forehead, over eyes, commenced at noon, and continued about 2 h.; pain in back and nausea; no appetite ; depression of spirits j disposition to weep. 27th. — 30 dr. Pain in sacrum all d. \ disrelish for food, especially bread, and repugnance to coffee ; on going to bed cold feeling in back, as if cold water were poured upon it. 28th. — In m. on awaking 1. chest was of bright red colour and hot to touch. 11 a.m., 30 dr. 2 p.m., dull pain over eyes, continuing about 2 h. ; same in small of back and sacrum all afternoon and e. No desire for food ; special dislike to bread continues ; depression of spirits with continual inclination to weep ; pressing in rectum and anus; cold chills in back, particularly after going to bed at

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n., with hot flushes towards m. 29th. — i p.m., 30 dr. Pain in back all e., till after midnight, when it abated somewhat. Symptoms now became so annoying that proving was suspended. Usual appetite for bread and coffee did not return for nearly three weeks. {Ibid.)

1. a. Mrs. N. W — , M.D., being in ordinary good health, began, Oct. 1st, 1869, by taking 3 dr. of 3rd dil.* 3 times daily. First noticed she was more active ; things went easily. No other effect for 4 d., unless it was increased sexual instinct j then sweetish nausea, with fulness of abdomen, particularly after eating, even after small quantities. Food does not increase the nausea \ no desire to vomit. On 6th d. moral symptoms were developed, did not want to be pleased, no care to talk or read ; desire to sleep \ slept well, but had unpleasant dreams. Omitted medicine id.; nausea and full feeling subsided. At intervals, skin of abdomen feels stretched and stiff; sore pain in upper chest. On 7th d. took 5 dr., and in a few m. nausea much increased, with same bloated feeling in abdomen, particularly hypogastrium, with some tearing from ovarian regions down both thighs ; darting pains in different parts of head. Ate, but without appetite j restless, and desire to be doing something, but no ambition \ sense of pressure in vagina, and pain at top of sacrum extending to hips. On 8th d., worse on going to bed ; cannot go to sleep j wild feeling in head as though she would go crazy \ dreaming all n. ; better on rising j constant nausea. On loth d., pain in r. iliac region, better during motion ; head grows wild after keeping quiet a little while. At 2 p.m. took 5 dr*, increased depressing weight over pubes, after supper j knees ache. b. Provcr came to Dr. Dunham on 22nd to state her symptoms, her mind being so affected that she could not record them. There came on 20th, and increased up till now, a sensation in pelvis as though everything were coming into the world through the vagina. Last n. sensation was very distressing, and not relieved by change of position. The dragging downwards is felt in stomach, and even in shoulders ; not relieved by lying down, but worse when standing up. There is disposition to place hands on hypogastrium and press upwards (also to inhale forcibly} in order to relieve dragging sensation \ likewise, aching and pressure across lumbo-sacral region, and some pressure upon rectum ; pressure also on top of head, with crazy feeling ; she wants somebody to talk to her and entertain her (very unusual) ; feels nervous, wants to cry from feeling of irritation and of something wrong in pelvis and abdomen ; feels hurried and yet incapable, as if she had a good deal to do, and could not do it. She is thirsty, drinking often and much. Her bowels are naturally regular ; but now she has alternate loose and solid stools, several during d., and constant feeling as though she must have a stool, resulting from sensation as though something were pressing on anterior walls of rectum at and near anus. She cannot get to sleep at n., but lies with eyes wide open ; grumbling pain in r. head and teeth. Her pelvic pains arc worse during, but still more after, motion. She is somewhat tender to pressure in ovarian regions, especially r.

c. (Dr. Dunham now continues report.) 23rd. — Aching in pelvis * The tincture used in the remaining provingit wai piepaxed trom the pollco only.

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as if not in uterus but around it. She feels constantly two spot corresponding in position to ovaries, which ache and feel like coals of fire. Same dragging sensation as before. 25th. — After reporting on 23rd (10 a.m.), desire for stool, and during d, stool every J h,, lumpy, small, diarrhcric, with wind ; constant tenesmus, she could sit at stool for ever, therewith burning in urethra, with tenesmus there also, and smarting after micturition. Helonias relieved, but she has still to-day the bearing-down — a pulling upwards and forwards from tip of coccyx, downwards and backwards from spines of ilia. Disposition to muse and dream, seems asleep and afar off, mental faculties benumbed so that she is indisposed for work ; headache in occiput and over eyes. Increased desire for meat, and has eaten much. 26th. — All yesterday pressure on bladder ; aching in r. ovary kept getting worse, feeling as if knife inserted there ripped down groin and front of thigh ; pain extended over lumbo-sacral region, and she had to he and cry herself to sleep ; pain extended up to r. hypochondrium and was somewhat relieved by pressure on ovary. This m. no pain, but the sore sensation which follows pain ; diarrhoea continues, also irritation of bladder, but she can control this by determining not to micturate; legs ache, causing her to twist and turn. It seems as if the symptoms came on worse as soon as she gave up active control over herself, f. g. when she tried to sleep. She thinks effects of medicine are passing off, because first symptoms, such as pain in occiput, are coming back. 28th.— Menses occurred yesterday, as usual, and regularly, and continued normal as long as she kept moving, but as soon as she came to rest the flow ceased. None this m. She cannot think, acts without thought ; feels hurried, walks fast instinctively ; is forgetful, cannot decide for herself, must depend on others. November 2nd. — She noticed on 29th some heart symptoms, not definite. On 30th, after walking, sudden fluttering sensation there. There is now hurried forcing feeling, with faintness and fluttering as though she could do nothing, but must put by her work and sit still ; seat of sensation is apex of heart, and twice she had sharp pain there. Great weakness in legs. She feels as if she must breathe quick, yet she does not. Prover feels that her whole system has been profoundly affected by the medicine ; "she is not the same person that she was ;*' she feels hurried, and yet cannot do much, has no heart or strength to attend to business, which has not heretofore been a burden to her ; she feels discouraged, but no longer has ideas of suicide as she had about 8ch day of proving. 3rd. — Gets out of breath going upstairs, must stop and rest; appetite tremendous, especially for meat ; does not care to be alone (contrary to wont), but does not dread it ; sexual instinct, ordinarily dormant, now much excited -, wits languid, intuitions dull. Bloating of abdomen continues. Can repress her symptoms and disregard them if she keeps very busy, but as soon as she ceases her occupation they recur with great intensity. 4th. — Much sweating in axilla, especially r. (noticed before); burning itching on swell of both deltoids ; heart symptoms passing off, felt now only on fast walking.

(/. From 4th to 7th felt quite well, but on 7th bearing-down sensation recurred, and was followed by thin acrid leucorrhGea,Teaving

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a brown stain, — these symptoms worse from afternoon to midnight; therewith mental depression and emotional irritation as before, — this came upon her like a sudden cloud. On tuh was in same state, with constant burning pain across hypogastrium, sense of irritation in womb, and great irritability of temper. On I2th leucorrhoea had ceased, but sense of irritation remained. Menses recurred on 14th (/. t, after only two weeks' interval)^ scanty, dark, and thick. Mental symptoms continued up to 22nd. From 30th onwards a third scries of Lilium symptoms came on, — passional excitement and hurried feeling, aching and burning pain in ovaries (distinctly defining these organs in her sensations) with aggravation at n., and diarrhoea in m. \ then despondency and mental depression ; then hurried feeling and impulse to work without real desire for it. With the ovarian irritation (always worst p.m.), there was pressure on bladder, urine being highcoloured and scanty : she could pass it every \ h. Dec. 8th. — Constant burning in back. On introducing finger into vagina she found the OS, which usually is so high as to be almost out of reach, now low and tilted back, pressing on rectum, while fundus lies on bladder. She now took platina as an antidote, and the Lilium symptoms gradually passed away. \Jhid.^ iS^o.)

1. Mrs. A. F — , M.D., took, Nov. 20th, 1869, 5ij of tinct. at a single dose. Had no symptoms for 2 weeks, but then came on chills creeping down back on going to bed every n. for a month, followed by violent beating of heart and throbbing of carotids, preventing sleep while lying on either side. These, and still more other symptoms ranging from Jan. 12th to April 5th, 1870, are very dubious cfFects of drug. {Ibid.)

2. Mrs. C. le B — , M.D., from Nov. 24th, 1869, took two doses of 3rd dil. daily for 6 d. Dull frontal headache all ist d. 2nd d., dull headache beginning in forehead and going all through head, worse on I. side; severe pressure in r. eye for 2 h. j chilly feeling all over body. 3rd d., same headache, mostly confined to forehead ; yawning and stretching ; severe chill towards e, causing great pain in and about heart, going through to under scapula j pain constrictive, heart feeling as though squeezed in a vice; blood seems all to have gone to heart, causing feeling as if she must bend double; can hardly walk upright \ therewith nausea. All these feelings removed on getting into a warm room. 4th d., same headache; stupid feeling; nausea, transient, suddenly coming and going ; heavy dull feeling in stomach, pains in r. ovarian region, a gnawing dragging sensation, worse on walking, a feeling as if something were shaking loose there whenever r. foot was planted firmly ; also gnawing pain in lumbar region, worse in bed and lasting all n. j sight (prover is hypermetropic) much worse than usual. 5th d., still headache, lumbar and ovarian pains, and nausea; sight worse, eyes very painful, smarting, must close chem often \ light pains, darkness pleasant. 6th d., eyes still bad, and though, no more medicine being taken, other symptoms gradually subsided, eyes took 4 weeks to return to their normal state, {ib'td.)

3. a, Mrs. B — , student of medicine, took daily from November 1st 5 dr. of tinct. at 6 a.m. Each d. "nervous symptoms'* came on

about 3 p.m., getting wone it efcrf VBcurrence* Trembling of was prominent among thoe I on 3ra Kimc tremor involved abdomen, lower back, and han<&. When walking jainti s<:cai co Jack •ynortai she can almost hear the crepitut. On 4ih evervthing m the least exciting causes cdd hands ; there b janlysii or ui^iine$s of finem, so that she can hanlly hold a pencil nnxily enough to write Mcoso delayed. After last dose sjrmptoins gndtially wurf off.

h, Dec. 7th, took, 2 h. bmre dinner, 1 2 dr. and at 8 p.m. had to leave companion account of cutting pain in bowcK so severe that she had to tace nux, which relieved 1 extremities cold and cljunmy; sudden chills not followed by fever, but with fulness of head. Woke next m. tremulous and weak as after sn iltncss. On 9th mcnsea appeared, scanty and of short duration^ appetite fstiled. Dec^ '3^"" 15th. — Fulness of head and pressing from wtthin ouiwardi a* it coa« tents would issue from every aperture, also aching of flesh and bofiet throughout body i latter recurred on 24th and 25th, with great soreness. Efiects of last dose did not seem to wear Away till aher nearly

4 weeks.

1. Mrs. J. F— > student of medicine, took 5 dr. of 3rd di]. twice on March 22nd, 1870, without effect. 23rd. — 8 dr. twice. No physical effects, but an h. after 2nd dote she noticed a nervous tremulousness, and inability to apply mind to any subject steadily « could not think clearly or remember weU. 24th. — 16 dr,, 3 titiicv. No marked change in feelings till afternoon, when she li^d severe pani in hack, much nervousness, inability to apply mind, depression, dj»posidon to weep, headache. On each d. increased secretion of urine* Took no more medicine till April 4th, when, feeling remarkably well, she took 1 j. dr., which was quickly followed by tremulousnc$s, J.nd peculiar presstve headache. {IM.)

2. Mrs. L. B. C, MJD. *«Oct, 8th, 1869, 1 took for one week

5 dr. of 3rd dil. n. and m. without effect ; then doubled do«c for another week. Now for a week have TcJt utterly incapacitated for mental work or physical exertion ; feel like sitting auictly without speaking or being spoken to, or compelled to think i dull heavy feeling in head ; everything seems unreal to me : my eyes look wild, and my husband fears I may become insane.'^ Afier writing above stopped medicine, and within 24 b. all nervous symptoms ceased, but ocxt period was not one fourth as much a& usual, and was followed by profuse bright yellow leucorrhoea, so acrid as to excoriate whole pennaeum. For some time after continued to have severe attacks of pain in uterus, lasting about i} h., during v^ hich she could not bear to he touched or moved, even jar against bed wm torture, and she could nut endure weight of clothes upon pelvic region. On examination womb was found anteverted.* (IM.)

1. Dr. LxLlBNTHAL, set. 54. "October 30th, 1869* — tiilium to be a cumulative medicine s it takes a long time to get any from it. I have taken in the last few d, nearly %j of dnc great results. Last e. felt irritable, sleep br(£m by dj dreams; arose earlier than usual, not refreshed by sleep |.i

• No. 10 alio experieuced out-presaing headsche as ia S Jb'

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full, especially over eyes ; reel and stagger when walking, with inclination to fall forward ; outward pressure in whole forehead ; cold chills run over face ; feel chillier than in cold weather, with hot congested sensation in chest ; usual cigar is nauseous and causes watcrbrash ; dull pressive aching from 1. temple over ear to occiput, in paroxysms, with steady dull frontal headache, especially over 1. eye. 31st. — Feel well, except for a little chilliness ; in c, burning in forehead, with burning pressing pains, especially over I. eye ; grumbling bellyache, with little inclination to stool ; not so irritable, but want to be let alone, and not troubled to answer questions, ist. — -Felt pretty well during d., but taciturn and reticent ; between 5 and 6 p.m., burning pressing headache returns, more in r. side of forehead, increasing in strength as c. passes on. 3rd. — Tookjss. During forenoon chillmess over face, followed by fever, congestion to chest, and slight momentary spasmodic twitchings around heart j dull pain in 1. temple, extending thence to forehead, with vertigo, especially when walking. Whole afternoon feel as if intoxicated, staggering forwards ; dull in head, obtuse, cannot find right word, forget what I want to say ; eyes full of water i face, especially forehead, Bushed and hot, and pricking sensation in skin of forehead. 4th. — Engaged in fresh air in forenoon, and no symptoms observable \ felt bright and clear in mind. £. passed in warm room ; old headache returned, with some lachrymation ; sensation as if a rubber band were stretched tightly from temple to temple, with old pricking sensation in forehead. 5th. — Was called out in n., and after lying down again was miserable and restless ; everything seemed too hot. In m. dulness of head, a kind of dizziness, more in eyes, before which there seems a veil; impossibility of getting a clear idea , oppression and heat of chest — a kind of ebullition ; must go into fresh air for relief, when headache becomes worse ; steady pain in lumbar spine, spreading both ways to kidneys, continuing all d. ; slight stitches occasionally in r. hip-joint ; staggering gait, have to exert myself to utmost to walk straight; chilliness from face downwards; burning hot urine, seeming more like oil than water; burning stinging frontal headache, with same feeling as of an elastic band stretched over it ; mind so muddled that I feared to lecture, — nevertheless, the more I spoke the better I was able to concentrate my mind on my subject ; eyes feel as if full of tears all d. ; disinclination to work, and lassitude in lower extremities ; oppressive and congestive feeling in chest, increased in e, ; irritable, depressed in body and mind, and unfit for work. 5th. — An h. after rising, pressive pains at angle between forehead and 1. temple, digging down into orbit, making me wink i pains spread over whole 1. hemisphere of brain ; congestive chill, continuing whole forenoon, in fresh open air, it commenced in face and extended downwards ; lassitude in thighs ; compressive sensation in chest, with choked feeling, as if I would suffocate, but would feel relieved if the blood could be discharged, which seems shut up in heart — slight relief by deep sighing ; heart feels heavy ; pulse small and weak, as if blood did not reach radial artery in usual quantity ; lowspirited, and not relieved by work. 7th. — P.m., usual headache; tearing pains in muscles of 1. upper arm ; frequent urination during d. ;

but unne not so hot. 8th. — Same symptoms, with smarting in urethra during micturition ; if desire to urinate is not attended to, uere it congested feeling in chest ; rousin? of sexual desire, which has been donnant &r years. 12th. — Felt well for last 3 d., save for a trifling headache every e. Awoke this m. irritable; increase of headache, which became severe towards noon, passing from forehead and temples to occipital pco> tuberances, pain dull, pressive, heavy, continuing whole e. and through n., with sense of burning internally and externally ; again chills running down from face, and congested feeling of chest. Felt burning hot aiQ m., with queer, half-waking dreams ; when awake time seemed much prolonged. 13th. — Woke unrefreshed, with fulness and weight in forehead. During d. make mistakes in speaking ; eyes heavy and si^t dim ; legs weak, as if unable to support body ; dull pressive pain uiMer sternum to r., relieved by sighing and pressure; screwing pain in L occipital protuberance, with drawing in 1. nucha, which increased 00 going to bed to burning sensation, whole neck feeling lame and tired ; pain in head shifts about, at last concentrating in 1. temple. Frequent urination. 14th. — Restless sleep, full of dreams ; emission towards m^ extremely rare. Woke with same dull headache. Palpitation and beating of arteries, felt only while lying in bed or during siesta ; amelioration of most symptoms in fresh air. During d., momcntaiy twitches in I. temple. From 15th onwards headache continued during d., worse in e., gradually lessened from 22nd, and on Dec. 1st leaving only tenderness in 1. forehead and temple, (At this spot since a slight sunstroke some years ago, I have suffered trom pain during the hot season, or after excessive mental labour, neither of which causes were in operation now.)" {Ibid.)

1. Mrs. M — , act. 28, took 2 dr. of i, dil., April 3rd, 1869, every

2 h. After a few h., sensation as if a hard body were raUingaround in stomach, continuing several h., but passing off in n. 4th. — ^ook 4 dr. every 6 h. Fine pains, sometimes gnawing, in r. chest, with Reeling of lameness and soreness of muscles, and desire to stretch parts ; lameness extended through to scapula of that side. 5th. — 6 dr. every 6 h. Gnawing and fine pains increased, and extended over to I. side. Voice much affected when attempting to sing, could not control it. Chest pains continued through 6th, but by m. of 7th had disappeared Took 6 dr. Bowels confined since 5th ; pain in lower sacrum. Confiisioa and dimness of sight, with disposition to cover eyes and press upon them. 8th. — 10 dr. In 15 m. pains in r. chest returned, with pressure and sense as of weight on chest. Craving appetite ; dry hacking coug^ in e., better in open air; pain in lower part of back, and griping u hypogastrium, followed by 4 loose stools the 1st d., and continuing the

3 subsequent d., with great languor. {Ibid,)

II. Poisonings, — I. Fanny B — , act. 4, passed an anther of the common yellow tiger lily into her r. nostril. There occurred at once profuse discharge of yellow-coloured mucus from the nose, soon followed by vomiting, first of chyme and then of mucus, coloured yellow. The child then wanted to go to sleep. Dr. Warren reached the patient at 6 p.m., August 13th, 1862, about an h. after the accident. The child appeared sleepy, but was easily roused, and was intelligent.

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Vomiting of mucus tinged yellow occurred while Dr. W — was present. The symptoms did not seem at all alarming. Dr. W — was called again at lO p.m. Evacuation of the bowels had occurred, at first natural in appearance, then yellow coloured, like the discharge from nose and stomach, and finally bloody. Opium and brandy were prescribed. Patient was seen next m. A dejection, quite bloody, had occurred between x and 2 a.m., and after that the discharge was checked. The child seemed languid and sleepy ; no vomiting or wandering. Eyes had a dull reddish injection. At 4. p.m., same. 8, condition unchanged ; r. nostril nearly closed, mucous membrane of both nostrils very pale, some discharge of thin clear mucus. Next m. (^5^^)) child looked brighter; eyes same; no urine passed during last 24 h. ; slightly feverish ; no delirium. 7 p.m., still no urine passed ; several stools, dark coloured and very offensive. Some fever during d., slight delirium and atartings^some nausea. i6ch. — Shortly before j a.m. she had had a large, dark-coloured, and very offensive discharge, and immediately began to sink. She died a little before 4 a.m., about 59 h. after passing anther into nostril. {Bost, Mid, and Surg, yourn.^ Ixvii, 279.)

Volume IV — Appendix

LILIUM.

(See vol. iii, p. 130.)

I. 13.* a. Dr. E. H. P—, sanguine temp., in good health, pulse 65. larch 27th. — Took 10 dr. of i, dii. at 7.30 a.m. At 10 began a pulsating headache, 1. side, that continued till e., worse from motion or noise, relieved by lying down ; eructations all d. 28th, — 15 dr. IDuIl heavy pain in ]. temple, with feeling as if head was enlarged; paroxysms of tearing pain in I. arm from shoulder to elbow ; dull heavy pain in region of heart j feeling of great weakness, with vertigo on sudden motion, continuing all d. \ faint empty sensation at epigastrium, with tasteless eructations ; urine exhibits large deposit of phosphates. 29th. — Pulse 80 when sitting before eating. Took 15 dr. X}uII, heavy headache on I. side, becoming throbbing after noise or jar ; foul taste in mouth, relieved by eating ; tasteless eructations ; great 'weakness all over ; slight exercise causes violent palpitation ; urine as Ijcfore. 30th. — No medicine j headache continues, seeming deep-seated, and attended by feeling of uneasiness; urine normal. 31st. — 25 dr. Pulse 87 sitting, 1 1 7 standing ; temp. 99° ; some headache, with pressure outward ; steady pain in bowels, relieved by soft dark stool. April ist. — Pulse 80 and 98, temp. 99° ; took 30 dr. Dull, left-sided headache from 10 a.m. to 6 p.m. ; dull heavy pain in region of heart from 2 to 7 p.m. 2nd. — Pulse 90 and no; took 35 dr. a.m. and p.m. Same headache, with general malaise, from 2 to 7 p.m. ; occasional pains in region of heart, increased by exercise ; sharp tearing pain from 1. shoulder to hand. 3rd. — Pulse 66 and 85. Took 40 dr. before eating and before retiring. Paroxysms of sharp pain in region of heart, so severe he must grasp the side, leaving feeling of great weakness all over. Pains in 1. arm continue. 4th. — Pulse qo and 120, temp, normal. Took 45 dr. m. and e. Headache continues, also pains about heart and in I. arm ; feeling of general prostration ; appetite lost. 5th. — Pulse 80 and 100. Took 50 dr. m. and e. Symptoms as before. 6tb, — Pulse 80 and 96, Took 75 dr. before eating. Head and heart symptoms as before ; neuralgic pains in 1. upper teeth, extending to ear ; no appetite. On 7th and 8th took same dose with same results ; from 9th to 13th took no medicine, and symptoms gradually abated. • None of the provers In this «erie» (13^17) knew what they were taking.

^. 14th, — Pulse 83 and 97. Took lodr.of tinct. m. and c, condn* ing such dosage up to i8th. Steady sharp pain in region of heart ; netr ralgic pains in 1. arm as before j rheumatic pain and lameness inlli when walking. 15th. — Pulse 87 and III. Same pains in heart a 1. arm ; darting pains in 1. face, from teeth to ear ; urine shows pho phates. l6lh. — Pulse 70 and 85. Same headache; circulation sea very weak, pulse very compressible, sphygmographic tracings since 9 are very low but regular ; still phosphates in urine, and so to end proving. 17th. — Pulse 72 and 90, Dull headache, worse to»-ardji some pains in heart and 1, arm ; severe pains in 1. cheek towards 1 and temple ; pulse much stronger. i8th. — Same symptoms, lyth Pulse go and 108. 20 dr. m. and e. Same symptoms ; great wei ness. 20th. — Pulse 68 and 85. 25 dr. m. and e. Same symptoi and great weakness of circulation -, skin becomes numb on pressu 2 1 St. — Pulse 70 and 93. Doses as yesterday. Same pains in face heart. 22nd. — Pulse 67 and 95. No medicine. Pains in head, fi and heart, with general malaise. 23rd. — Pulse 73 and 94. 5^ before eating. Pains from teeth to car very severe, also about he and down arm ; some vertigo and nausea all d. ; circuJation ve 24th and 25th. — No medicine ; symptoms abating. 26th. — Pulse and 103. Took 50 dr. in m. ; pains returned violently, arm sMi weak; hiccup and eructation. 27th. — No medicine j symptoms ihi ing. 28th. — 50 dr. Headache and cardiac pains as before. 29th, No medicine i symptoms abating. 30th. — Pulse 93 and 120; 50 in m. No new symptoms. JVlay ist and 2nd. — No medicine ; 57I ptoir.s quite gone by 2nd. 3rd. — Pulse 98 and 129. Took 85 before eating ; pains about heart return ; pulse irregular, increased slight motion ; face-ache returns in paroxysms, quite severely ; frequi urination. No more medicine taken. On 4th, pulse 65 and i headache and great prostration ; trembling and weakness of I. art numbness in various parts, sth. — Pulse 69 and 78 , dull hcadaci malaise, and exhaustion ; no other symptoms. Sexual desire « markedly increased from April 17th onwards, and nocturnal emissiC were frequent. {liiii/., 1886, p. 237.)

1. a. W. H. S — , a healthy man, of nervous-sanguine temp pulse 75, resp, 17. March 9th. — Took lO gr. of I, trit. before catil No symptoms during d. ; in e, was restless and nervous. lotiv Twitching sensations about head and in pectoral muscles j »lij frontal headache, i ith. — Headache over 1. eye, worse on motion si out of doors I slight vertigo; nervous feeling in 1. chest; crott irritable. I2th. — Nervous and restless all d. Took another to | 13th. — Same symptoms, T4th. — Same nervousness; urine of sci odour, sp. gr. 1021, increased phosphates. 15th. — Feel Jess nervo^l urine as yesterday. i6th. — Well as usual; urine normal. 19th,' Took gr. 34 of crude drug before eating. No symptoms during i slight headache towards n,, with increased pulse. 20th. — Awokewi sharp pains through r. lung, worse out of doors ; some headache * vertigo ; nervous feeling returns, with twitching about heart. Ji — Sharp pains in che&t have subsided, but twitching in heart reauis Feels exhausicOi •, umc oi ivtou^u^ovw s ^«i^V».v«A.tt excess, zi"*

\» yesterday. 23rd.— Nervousness continues ; no pains ; some ulence and two actions of bowels (unusual). Twitching in heart dually subsided, and by 26th he was well.

i. May 2nd. — Took 10 gr. of crude drug before eating. Soon :r throat began to feel sore and dry. 11, throat worse, face flushed, 4iache in occiput and r. side ; pulse 78 ; legs feel heavy } shooting OS in various parts, worse in chest. 3, pains in throat less severe ; 3asil enlarged, slight exudate upon it ; pains all over at times } very CaUe and cross, feel like swearing; nervous feeling is returning, not apply mind to business or anything else. £., mind runs on d thoughts } feel very *' u^y -/' want to swear one minute and a lewo story the next (quite unlike usual disposition) i nervous tcbing in 1. chest returns. 3rd.— -Passed a very restless n., dreaming iptuously all the time; **to say I feel devilish will express my loing exactly ;" throat improving. On waking this m. was seized h severe pain, extending from os pubis through to rectum ; it was :re and cramp-like, and was relieved only by movement of bowels } etite capridous, wants sour or sweet dainties, this craving alternates h desire for food } mental state continues same, *' lewd thoughts tess me, I want to swear without cause, I never experienced such a e before." 4th. — Slept poorly } horrid lustful dreams all n., felt austed by them ; frontal headache } mental state as before ; throat rly well } urine of strong odour. 5th.— Slept better last n. roat about well ; bad taste in mouth } twitching in 1. chest continues. — 8th.^AU symptoms subsided. {Ibid.)

1. T. J. B — , man of phlegmatic temp. ; in good health, pulse 78. 9 27th. — Took 10 ^r. of crude drug at 8 p.m. Heaviness of head 3 drowsiness, yawninz, and languor } dull aching in small of back, sending forward it feels as if it would break ; legs feel too heavy to j; soreness all along spine with stiffness, cannot bend forward lout pain ; sore aching in region of scapula. All symptoms resd by sitting, or standing, or walking about. At 3 a.m., pulse 86 ; le light-coloured and profuse. a8th. — Pulse 86. Took 5 gr. of ie drug. Dull frontal headache } itching of hand as if stung by ies i pain along spine, worse in lumbar region } feeling of lump in lat, with pulsations in it when lying down ; sharp neuralgic pain r 1. eye, extending to vertex ; heavy tired feeling in legs, with >ting pains from groin down inner side to knee. 29th.— P. 80 ; ralnc pains in frontal region ; pressing pains in cardiac region ; e light coloured, profuse, with whitish sediment ; stool difficult.

2. A. W. W — , man of lymphatic temp, j has never been ill ; c 65. April 3rd. — ^Took 10 er. of 2x trit. dry on tongue at ; a.m. 7.30, neuralgic pain in T. testicle, inf. and post, portion, of lentary duration, but returning at intervals for ^ h. 7.37, algic pains in r. temporal region, afterwards in r. foot and toes. , peculiar taste in mouth, no cause ; neuralgic pains in foot, also in r. 7.55, salivation, with chilliness down back ; pulse normal. 8, algic pains in r. temple and foot ; itching of csdf. 8.15, chilliness ms, rumbling and griping in bowels. 8.20, pressure in peciaa&uttv \ >!.. IV, i,\

r, frontal headache. 8.35, nose stopped; drawing in 1. inguinal region ; testes tender to touch and seem swollen, 9, repeated chilliness ; pulse normal ; feet and hands cold ; sharp pain in I. hypochondrium, increased by motion, 9.15, no appetite for breakfast ; eating ‘causes desire for stool, which is loose, with much flatus ; testes sore and heavy during m,, wished I had a suspensory bandage to wear, Ibid.

¢ 2. Miss M. de N—, florid complexion, sound health, pulse 78, resp. 19. Jan. 7th, 8th, and gth.—Took ro gr. of 6x and 2x trits. without effect. 1oth.—Took fo gr. of 1, at 11 a.m, Soon felt pain in r. ovarian region, dull and oppressive, increased by deep inspiration and by motion; pain continued till noon. 9 p.m., sharp neuralgic pains in], side of head, quite severe ; came in paroxysms and continued some time, 11th.—g a.m., pain in head gone, but it feels weak and confused ; languid feeling ‘all over and no appetite for breakfast 5 tongue is much coated, yellowish white in patches, 13th.—Coating on tongue now gone, and she is well as usual, (/bid.)

18, Mrtusow R. Auten, student, took 5 gr. of crude drug with no effect, (Ibid, 1888, . 145.)

1. C, W, Bewgpicr, student, took same with like absence of result.” (Ibid.

2. B. L. Baker, student, health good, uses tobacco and coffee. 1st d.—Took § gr. of crude drug at 8am, P.m., had some pain in lower bowels due to wind, and relieved by passing offensive flatus. and d.—No symptoms. 3¢d d.—At 10.30 a.m. sudden stitching pain in region of 1, kidney, worse from deep breathing ; lasted about an h, No stool. 4th d.—Same pain as yesterday, and at same h. Some collection of flatus causing colicky pain and relieved as on 1st d, No stool. sth d.—Bowels moved slightly at 8 a.m. ; stool at first hard, then soft. At 11.30 loose stool, preceded at 10.30 by fatulent pain, quite severe for a few moments, 6th d,—Two loose stools in m., relieving pain in lower bowels which preceded them. No further effects. (Jdid.)

3. a, T. L, MACDONALD, student, health good, uses no narcotics or stimulants, 1st d—Took 5 gr. at 8.15 am. In 15 m., while singing, slight dull aching in forehead, from temple to temple, more marked on r. side ; it continued during d, About 11 a.m. fancied he felt slight trembling and weakness, especially in legs, while standing. On next 4 m, was awakened early with sexual orgasm.

b, After 3 weeks took 10 gr. at 8.30 a.m, fasting, At 11 heart and pulse were acting with increased force. No further effect from drug ; and two additional doses of same, on 3rd and sth d., were equally without result. (Ibid)

1. W. F, Minnarp, student ; health good, uses no narcotics.

—Took 10 gr. at 11.50 a.m., at which h. pulse was 76 lying, 80 ing, go standing; temp, 98°6%. and d.—At 10.40 p.m. pulse 66 lying, 72 sitting, 80 standing; temp. 97°2°. Have had a dull indescribable occipital headache, which began before I rose in m. and went off during supper ;, worse from stooping and after going upstairs. At different times little aching pains have seemed to locate themselves for a moment in one place, these go off, and after a while come again in

Ist

some other part of the body. Since noon have had some dull backache

in lumbar region, worse while sitting -, and have urinated ofteiier than

usual since 2.30 p.m. (urine natural). Feet cold greater part of d., and

cold chills have gone over body occasionally. 3rd d. — Slight occipital

headache since 10 a.m., lasting till after supper. Since noon have had

backache, centring from 4 to 5 p.m. in lumbar region. 4th d. — For 5

m. after breakfast distressed sensation in epigastrium. From 4 to 5

p.m. headache in occiput, with the backache and a tired feeling. Now

ind then in afternoon piercing pains in upper third of femur. 5th d. —

About 1.30 a.m. awoke with dull heavy occipital headache and sick

icomach. In a short time went to sleep again, but had troublesome

ireams. Arose at 7.30, with back part of head feeling too large, and

with sense of fatigue ; but all symptoms passed off after breakfast, and

I have since felt quite well. {3id.)

23, Everett B. Finney, student, took 5 gr., and, a week later, 10 gr. without effect. {Uid.)