Coccus cacti

автор Richard Hughes & Jabez P. DakeA Cyclopaedia of Drug Pathogenesy

Volume II — Main text

Cochineal. (The entire insect so named.) I. Provings.- 1 . Dr. CASPAR, æt. 30, in good health, took the 3rd dil. on 2 d. without result.-May 3rd, m., 10 dr. Ist dil. No effect. -4th, e., 10 dr. Ist dil. Woke early, then fell into a half sleep which was disturbed by frequent painful tearings in a r. carious molar. -5th to 8th., took m. and e. 10 dr. of Ist dil.-5th. Slight indescribable pain in pit of stomach and 1. hypochondrium. Frequent cold feeling in shin or r. shoulder and r. side of back. Sleep disturbed by tearing in tooth.-6th. Toothache returned. Pressive pain in stomach. Pressive pain in r. temple. On turning head shooting pain in muscles of 1. side of nape. Sleep with unremembered dreams.-7th. Pain about navel, occasionally extending to ossa ilii. Shooting pain in nape. Sleep disturbed by toothache and by great dryness and scraping in fauces and especially in soft palate.-8th. Frequent dry hawking and short cough with increased thirst. Shuddering along spine. Pain in both thighs along the course of the large vessels and nerves. Drawing spasmodic pain in r. calf. These pains and similar pains in shoulder, foot, &c., frequently occur. Scraping and dry feeling in throat increased towards e., hence frequent hawking and cough. On lying down violent cramp of 3 last toes of r. foot. Woke early.-9th. Itching of skin on extensor surface of limbs, on belly and back, sensitiveness of tubera ischii when sitting, small red spots and itching papules in various parts of skin ; dry cough.-Ioth . 10 dr. , same symptoms as yesterday, but the cough was loose, expectoration of small quantity of mucus ; a small vesicle on tongue ; here and there shooting-tearing pains in muscles , especially in r. hip-joint, very severe when rising up and moving quickly.- 11th, m., 10 dr. Easy expectoration of considerable quantity of mucus ; pressing pain in occiput with swollen feeling of scalp extending to 1. cheek and side of nose ; frequent cramp-like drawing in r. calf. E., 10 dr. Early waking and half sleep, cramp in r. toes.- 12th and 13th. 10 dr. , slight drawing and pressing in occiput, temples, and r. eye ; nose dry, stopped up ; very frequent cough with moderate expectoration ; occasional hoarseness.. Though no more medicine was taken the disturbed sleep and pain in muscles lasted several d., also the pain in hip-joint and tubera ischii. Throughout the proving stool irregular ; thirst increased, especially m., appetite variable. The symptoms were worst in afternoon. (Oest. Zeitsch. f. Hom., iv, 509.) 2. Dr. E. H. FRÖHLICH, April 29th, 8 a.m., 3 dr. 6th dil.-30th. Shooting pain in a small spot of 1. side of chest aggravated by walking but not by deep inspiration.-Jan. 12th, m., 5 gr. 3rd trit. No symptoms .-25th . 10 gr., feeling of roughness in throat with hawking of mucus. E., difficulty of swallowing, swollen feeling of larynx with difficult speech ; sweet taste ; feeling ofcommencing sorethroat.-26th. Pressure, weakness and bruised feeling in chest, frequent hawking of mucus, slight difficulty of swallowing ; soft palate and pharynx slightly reddened ; in r. arch of palate a pustule the size

of a hemp-seed ; after talking pain and rough feeling in larynx. These symptoms lasted 5 d. The 3 first d. copious loose stool .-Sept. 17th . 10 gr. Ist trit ., frequent, not copious, micturition ; squeezing, pressive pain in middle of chest.- 22nd. Same dose. Soon 1. lung affected with fine pricks behind middle of sternum, going off after breakfast, all d. frequent and copious discharge of water-clear urine.-24th. Same dose. Immediately deeper tone of voice. Urine as before.- 25th. 20 gr. Ist trit., feeling of pressure and fatigue of chest ; next d. pricking in larynx, hot breath, expectoration of large masses of whitish grey mucus ; pressure and fatigue of chest, increased by walking in open air ; rough feeling during and after speaking ; frequent discharge of watery urine; pricking in thoracic integuments and region of stomach on exposing the abdomen.-Dec. 10th, m., 10 dr. tinct. Immediately pricking pressure in stomach lasting all d.- 11th, m., hoarseness, copious discharge of urine as clear as water, which seemed to have the consistence of oil. At n. amorous dreams. ( Ibid. , 512. ) 3. THERESIA KUMMER, æt. 33.-April 30th. 2 dr. 6th dil., no symptoms till next d.-May 1st. Shooting pain in 1. side and 1. scapula extending to 1. elbow, increased by moving arm.-2nd. Pain continues and spreads to sternum with pressive pain in chest, anorexia, and white furred tongue. These symptoms lasted with diminished severity till 4th.-26th . 10 gr. 3rd dec. trit. In e. chill all over body.-27th . Chill continues all d.; sore pain in throat, hoarseness.- 28th. Chill continues. In e. slight cough with shooting pain in temples, roughness and soreness in throat. Menses came on at proper time.-29th . Sleep broken ; after rising exhausted feeling in limbs, shooting pain in temples, with painful fulness of head ; nose felt stopped, with watery discharge from it ; redness of nostrils and sore feeling there ; soreness of throat, hoarseness, short dry cough ; slight redness of throat, no pain on swallowing ; pressive feeling in middle of sternum, spreading to both scapulæ. No thirst, anorexia, pulse accelerated, 76. Headache and fatigue so great he had to sit down several times during a moderate walk. These symptoms relieved by drinking tea.-30th. Woke at 4 a.m. with same symptoms as yesterday ; soon afterwards cutting about navel, every movement aggravates her sufferings. The symptoms gradually decreased. ( Ibid., 516.) 4. a. F. GOTTWALD, surgeon, æt. 33, took from Jan. 27th to Feb. 6th, every other day, Oj of 3rd dec. trit. -Jan. 27th. Bitter taste, hardness of hearing as though ears were stopped with cotton ; cold feeling in occiput as though blown on. E. sacral pains, increased at n.- 28th. Slight vertigo ; pressure in both temples ; feeling of fulness and tension in bladder, without inclination to urinate ; the tension remained after emptying bladder ; after dinner griping in bowels and fluid stools. E. and n. , irritation to cough in larynx, disturbing sleep.-29th. Bitter taste ; dry throat as if full of dust ; after dinner heartburn for 2 h. E., increased dryness of throat, accompanied by slight burning in soft palate. -30th. Catarrhal symptoms of pharynx and trachea continue slightly ; cross without occasion ; after eating heartburn. E., uncommonly cheerful.- 31st, m., great weakness and drowsiness ; during d. bitter taste. -Feb. Ist. Very restless n., no sleep ; the whole body felt swollen ;

in semi-somnolent state, imagined his body had turned into a bagful of wool ; everything he touched seemed thicker ; all d. dazed head.-2nd. Bitter taste, good appetite for breakfast ; afterwards confused head. Later, restlessness drove him out of house in very bad weather.-3rd, m., violent griping in bowels, then liquid stools, 3 during d. Frequent sneezing, hoarseness, dryness ofthroat, thirst. E., slight fever.- 4th. Restless sleep disturbed by dry cough ; bitter taste ; transient vertigo ; scraping in throat, relieved by eating ; pain in sacrum ; irritation tocough ; cutting pains in abdomen. E., feeling ofswelling ofhead, anxiety. Later, dry throat, tension in soft palate.-5th, m., constant dry cough ; increased sensitiveness of fauces and gullet, so that rinsing mouth made him cough, and brought on vomiting of thick masses of mucus. After dinner smoking caused cough. E., anxiety. N., heartburn.-6th. Roughness in mouth, tension, and great sensitiveness of soft palate. Brushing teeth caused violent cough followed by vomiting ofmucus. Noon, griping of bowels and pappy stools. Good appetite ; after eating, heartburn ; confused head, coughing and sneezing ; great drowsiness e.-7th. Increased sensitiveness of fauces ; tearing pain in r. shoulder and sacrum ; griping in belly. In e. the shoulder pain extended to forearm, and was sometimes very violent. b. On Feb. 18th, 21st, 24th, and 27th, and March 5th and 9th took Əj Ist dec. trit.-Feb. 18th. Soon, bitter taste, dryness of throat. Noon, loss of appetite, increased thirst ; slight inclination to vomit, relieved by drinking diluted wine.- 19th. Slept well. M., great lasciviousness with slight erections. All d. prostration of limbs. After dinner great thirst, drinking cold water to allay it caused unusual chilliness. Must drink cooling liquids to refresh throat. Smoking caused cough.-20th. Restless sleep at n. In m. confused head with slight vertigo. During d. frequent dry cough and sneezing ; dryness of m.m. of nose and fauces, relieved by drinking water. Smoking caused burning in fauces.- 21st. A sickening irritation in fauces as if tickled with a feather, bitter taste, dryness of m.m. of nose and fauces. Afternoon, when smoking, burning in throat and lips. E., confusion of head.-22nd. Woke with dryness of throat, relieved by drinking cold water. M., great urging to urinate, which was performed with erection ofpenis and lasciviousness. During d. fatigue of limbs, dazed head, stuffed nose. Afternoon, sneezing, coughing, sensitiveness of organs of deglutition.- 23rd. On waking dryness of m.m. ofmouth and fauces, tongue stiff and hot ; desire to drink water to keep the organs of deglutition moist ; skin dry, hot, cold water moderated the heat. During d. frequent discharge of thin nasal mucus ; roughness ofthroat, frequent sneezing, dry cough.-24th. Frequent waking fromdryness of throat ; tongue so dry and rough that it makes a noise against the palate ; tensive pain on swallowing, relieved by drinkingwater. In m. tickling in throat causing inclination to vomit ; bitter taste. During d. dazed head, frequent chilliness ; sneezing and cough with yellow expectorations. Thinking of cochineal causes loathing and nausea.-25th. Slept restlessly on account of sexual excitement. During d. very sleepy. E. , chills, cough and sneezing.-26th. Frequent waking on account of dry throat and tensive pain in soft palate; scabs form on outside of

nostrils ; sensitiveness of throat, restlessness, chills.-27th . On waking dry, brown furred tongue, cough with expectoration of globular mucus ; sore-throat, bitter disgusting taste, confusion ofhead, anxiety, and restlessness.-28th . Lascivious dreams. Sleepy in m.; the roughness in throat, frequent cough, and sneezing all d.-March 1st. The dryness of m.m. continues, yawning and stretching of limbs, tensive pain in sacrum.-2nd, 3rd, and 4th. Same symptoms continue.-5th. Bitter taste, scraping feeling in throat, causing inclination to vomit ; catarrh of larynx and trachea increased ; smoking causes cough. Afternoon, heartburn, and tensive pain in throat.-6th. On rising in m. tickling in palate causing inclination to vomit ; vomiting of mucus from rinsing mouth. No appetite for breakfast ; later, ravenous hunger. Catarrh continues.-7th. On waking long-continued coughing without expectoration ; no appetite ; confused head. Afternoon, dry throat ; tensive pain in soft palate, must drink often ; violent stitches in 1. ear . Ε., griping in bowels, followed by pappy stools with chilliness.-8th, m. , drycough for some minutes with expectoration ofmucus. No appetite ; continued inclination to vomit. E., very drowsy.-9th. Soft palate very irritable, speaking and brushing teeth cause vomiting. During d. great restlessness .- 1 oth . Wakes early ; yawning and stretching limbs ; lasciviousness without erections ; irritation of throat, brushing teeth and rinsing mouth cause cough and inclination to vomit. Coughing and sneezingwith mucous expectoration continue. These symptoms continued several d., and only ceased on the 16th. (Ibid., 518.) 5. a. Dr. HUBER took, Feb. 5th, 25 dr. 6th dil. Frequent quivering twitching of l. lower eyelid ; repeated pricking smarting in various parts of skin.-6th, 8 a.m., 40 dr. After 2 h., voluptuous tickling in both ears extending from external meatus through inner ear to buccal cavity for 15 seconds, with flow of tasteless saliva and smarting-pricking in skin over r. clavicle. During d., frequent quivering twitching in 1. lower eyelid. E., in bed, smarting pricking in r. pectoralis muscle and r. groin.-7th, 7 a.m., 15 dr. After h., short, smarting pricking in back of r. hand ; violent stitch on inner border of 1. patella, like electric sparks ; great itching in r. concha and external meatus. About noon, smarting pricking in 1. side of tip of tongue and much tasteless saliva. E., violent stitch in r. patella like electric spark.-8th, m., 25 dr. After 1 h., while still in bed, dull, digging, intermitting, undulating pain in posterior part of r. parietal bone, followed by short shooting-tearing pains in fleshy part of anterior internal aspect of 1. upper arm. Afternoon, frequent smarting sensation on small parts of hairy scalp, and twitching pricks on 1. sole near toes ; continued rumbling in abdomen under r. short ribs. E., dull digging pain in 1. occiput towards ear.-9th, 6 a.m., 35 dr. After h. in bed had first short tearing pain along anterior internal part of r. thigh, then a similar pain on outer side of r. upper arm, and later painful drawing in metacarpal bone of r. thumb and pricking in r. internal malleolus; frequent smarting pricking in gums of the r. incisors, great dryness of mouth and frequent itching in 1. meatus auditorius. Noon, violent pressive pain near 1. elbow-joint ; intolerable itching in the furrow on under surface of l. big toe. After dinner frequent tearing pain from r. scapula

over anterior outer surface of r. upper arm. 3 p.m., 50 dr. 7 p.m., on several points of abdominal integument short prolonged pricking smarting as if leeches were sucking there ; I h. later some smarting near r. nipple and in foreskin . 10 p.m., in bed drawing-tearing pain above and behind 1. ear followed by continued noise in it. At n. vivid, remembereddream about syphilitic sores .- 10th. Woke in m. with slight dull digging in r. upper molars and dull headache above r. eye. 15 dr. 4th dil., no effect ; 3 p.m., 30 dr. E., in bed, smarting pricking here and there in skin even in scalp ; then intolerable itching in 1. meatus externus, relieved by boring in finger ; great roaring in 1. ear, like a storm in an exposed forest. Woke at 4 a.m. with bruised pain in 1. clavicle and shooting pain in pit of stomach, on every inspiration, goes off during expiration ; this lasted 5 m., followed by shooting pain in r. flank, spreading from border of faise ribs to r. side of back, aggravated by pressure and relieved by discharge of flatus. This pain lasted 10 seconds and was followed by drawing pain in muscles of r. forearm, itching and roaring in 1. ear and pricking as from splinters of glass in under surface and tip of 1. big toe.- 11th, 8 a.m., 40 dr. After 3 h ., violent stitch in interior of r. ear followed by slight aching in a r. upper molar. Bruised pain in l. clavicle continues, increased by moving 1. arm ; when lying changes to dislocation pain in 1. shoulder. After dinner, pain in r. parotid, followed by a similar pain in r. salivary gland under tongue, much tasteless saliva ; painful drawing in interior of r. ear. 3p.m., continued pressive-tensive pain in l. mastoid process ; simmering noise in l. ear, sore pain between l. eye and lid as though a hair had got in eye. Afternoon, 50 dr. 7 p.m., several violent stitches in 1. inner malleolus and smarting stitch in r. external meatus and r. temple. E. , in bed, pricking as from glass splinters at one time under nail of 1. big toe, at another in finger-tips and under nails of r. thumb and index. -12th, 7 a.m., 60 dr. After h., griping in bowels above pubes as from incarcerated flatulence lasting 15 m., relieved by discharge of flatus ; bruised pain in 1. lumbar region and slight pain in l. lower molar. After h ., drawing-shooting pain from 1. flank along 1. hip for some seconds. After rising, diarrhœic stool followed by pappy stool with prolonged discharge of flatus. 9 a.m., short shooting pain on ribs of cardiac region in a place the size of half-a-crown, with raw pain on pressure. 11 a.m., violent smarting shooting on 1. antitragus, bruised pain in 1. clavicle with dislocation pain on moving head or l. arm or when lying on 1. shoulder. After dinner, some anxious, rapidly repeated irregular heart's beats. 4 p.m. , 70 dr. After h. when walking in open air intolerable itching smarting, now in r., now in l. antitragus, followed by painful cramp-like drawing in interior of r. ear. E., in bed for some seconds digging-shooting pain deep in r. lumbar region, apparently in kidney ; soon afterwards extremely violent stitch, making him start ; shrill ringing in interior of 1. ear with bruised pain round 1. external ear, especially in mastoid process ; this pain extended along 1. side of neck to clavicle and thorax ; woke at midnight, felt a prick in occipital scalp like a leech-bite. Disquieting dreams, well remembered. On waking m., feeling of a hair in eyes causing smarting, then a short drawing-pinching pain in interior of 1. ear, dryness of

mouth and smarting on tip of tongue as from pepper. After some m. drawing pain in l. clavicle worse when lying on 1. shoulder ; drawingtearing pain along front aspect of muscles of r. upper arm, when at rest ; pressive pain at side of 1. patella ; frequent sore stitches on various parts of skin and scalp, conchæ, r. side of nape of neck, border of both lower jaws, near nipples, on back, on scrobiculus cordis, axillæ, groins. All these symptoms went off when he got up. b. Feb. 13th, 6 a.m., 10 gr. 3rd trit. After 2 h. several sore stitches on border of 1. false ribs between stomach and 1. flank, deeply seated. All d., pressure in stomach as from indigestible food. Frequent itching in interior of 1. ear, especially when coming from cold air into warm room ; painful pressive tensive feeling in bones close above and behind 1. ear, especially in mastoid process, at same time much tasteless saliva. Afternoon, tearing shooting along r. calf-muscles and shooting pain in muscles in bend of r. elbow when at rest. 4 p.m., 20 gr. In bed in e. the pressive-shooting pain in bones about 1. ear, increased to painful digging undulation involving the l. side of neck and clavicle, the 1. molars and 1. occipital region ; frequent sore stitches in l. antitragus and constant tiresome roaring in l. ear. Many dreams at n.-14th, m., 30 gr. In + h. violent prick like a leech-bite in bend of 1. elbow ; short, drawing pain in upper and outer side of 1. thigh. II a.m., first short drawing pain on upper and outer side of 1. thigh when at rest, then a stronger and deeper prick close in front of 1. ear between antitragus and zygoma ; drawing pain in l. concha worse when touched ; when chewing pain of 1. maxillary joint close to ear, with cracking in it on swallowing. After dinner recurrence of the pain in mastoid process and clavicle, with constant roaring in l. ear. 4 p.m., 10 gr. 2nd trit. Immediately a violent prick in front ofl. elbow and in r. patella. 10 p.m., in bed, tearing shooting along anterior inner muscles of thigh. Midnight, when half asleep, sudden, very violent palpitation of heart lasting 25 seconds, as after severe fright, shaking whole body in repeated fits.-15th. On waking, m., bruised pain in 1. sacro-iliac region. 7 a.m., 20 gr. Throbbing pain, synchronous with pricks in interior of 1. ear ; cracking in it when swallowing ; feeling as if ear were stopped, without affecting hearing, accompanied by pressive tensive pain in 1. mastoid process, which on one side spread over 1. side of neck in region of clavicle, on the other side to 1. molars, after h . , aggravated by lying on 1. ear and lasting all d.; feeling as if liquid wax escaped. 4 p.m., 30 gr. After I h., great dryness of tongue and whole mouth with great thirst for cold water. 4 a.m. , woke without cause and then there occurred slight pricking as from a glass splinter under nail of l. big toe.- 16th, 15 gr. After I h., disgusting, sickening taste ; itching in r. external meatus and drawing, sometimes shooting pain in interior ofr. ear ; great roaring in l. ear and sore pricks in various parts of skin, even in prepuce, as from leeches. II a.m., tearing-shooting pain along 1. sciatic nerve from l.glutæus max. to posterior and outer side of thigh . 3 p.m., 30 gr. rst trit. After 2 h., slight con . fusion of head and prostration of whole body ; pressure in stomach as from indigestible food. E., frequent itching and roaring in l. ear . In bed before midnight violent pressive throbbing pain in l. mastoid process,

increasing sometimes to digging-outwards, and spreading to interior of 1. ear, 1. occipital-nuchal region,1. molars, and along sterno-cleido-mastoideus muscle to 1. clavicle and sternum ; these parts when touched are painful as if ulcerated ; when swallowing saliva cracking and feeling in 1. ear as if wax would flow out ; at same time tiresome heat and tinnitus of 1. ear. Sleep restless and not sound, frequently wakened by slightest noise with a start,with palpitation.-17th . Woke with bruised pain in l. lumbar, sacral, and hip regions ; 1. ear felt stopped, hearing impaired. From 17th to 23rd the symptoms of ear and hearing continued in slight degree. From 23rd to 28th no trace of ear affection except occasional roaring ; for a long time momentary drawing or tearing in various muscular parts like splinters stuck in ; this pain occurred in the upper arm in bed at n. , when he exerted the muscles slightly. During proving the urine generally deposited a red sand, and the sexual desire was somewhat increased. (Ibid., 523.) 6. a. W. HUBER, surgeon.-March 13th. 30 gr., 6th trit., fulness in stomach with retching all d.-14th. Same dose, same effect.- 15th. 100 gr., immediately, weight and pressure in stomach. Frequent retching. Feeling as if a crumb were sticking behind larynx. Dislike to food and drink. After taking soup pain in forehead, aggravated by shaking and turning head and even by moving hands ; at same time nausea with inclination to vomit. E., in bed, feeling of heat, and like a throbbing all through body.-16th m. 100 gr. 5th trit. All d. as if a stone the size ofa fist lay in stomach, and as if a crumb stuck in throat ; 3soft stools mixed with hard lumps. Afternoon, when walking, prickling feeling in anterior surface of thighs, as if heat streamed through skin, lasting 10 m.-17th m., 100 gr. same trit. In 1 h. same feeling in stomach and throat as yesterday. The crumb in throat seems often to move up and down. This feeling lasts all d.; two soft stools. Bad appetite.- 18th, m., 100 gr. 4th trit. Soon same feeling in stomach and throat, at same time sensation as if the overloaded stomach (he had eaten nothing) must relieve itself by vomiting. On swallowing fluids felt as if they were jerked down spasmodically. Afterwards burning in œsophagus. Little appetite, food blows stomach out, stomach sensitive to touch. E., heartburn with eructation of acrid fluid. On rising at 5 a.m. the stomach and throat felt all right, but the feeliug recurred whilst walking. After smoking, while walking, heartburn and transient jerking pain in l. lower canine tooth.- 19th. Theb. symptoms 25th. 100disappeared. gr. 3rd trit., soon pressure in stomach and retching. After 2 h. pressure in stomach increased, the retching was more frequent and a feeling as of a lump the size of a walnut sticking behind larynx caused constant swallowing. Afternoon,heartburn, very troublesome retching, and great pressure behind larynx. 4 p.m., burning feeling behind larynx as from acrid fluid. After a mouthful of wine great heartburn and pressure in stomach till 8 p.m.-26th . 100 gr. Forenoon, only roughness of throat. Afternoon, whilst walking fast fore part of 1. foot painful when treading, the articular surfaces of tarsus felt swollen, thereby impairing the mobility ; two soft stools.-27th. 100 gr. 2nd trit., during d. transient tearing pains in r. little finger

and 1. big toe when moving. E., after lying down, transient tearing pains from 1. eye spreading up into forehead.- 28th. 100 gr., only slight heartburn.-29th. 100 gr. Ist trit., after I h. roughness in mouth and throat, feeling of a crumb in throat with retching ; pressure in stomach. Whilst walking the retching and pressure behind larynx increased ; heartburn and great exhaustion. Afternoon, while walking internal hot feeling in chest, especially severe in cardiac region and in lower half of r. chest ; then sensation as if an artery beat on the surface oftheheart, several times (for several m.) whilewalking. Head, especially in e., confused as if intoxicated. N., restless, could not go to sleep on account of internal heat.-30th. On waking m. intoxicated confusion ofhead. Same dose repeated. Same hot feeling in crown and deep in chest, sometimes amounting to burning, especially in cardiac region. 9 a.m., when walking, warm feeling in whole belly. On anterior surface of thighs prickling as though electric sparks were drawn from it. When this ceased, heat in chest, especially in cardiac region, and occasional pulsatingbeating in heart. This feeling attended with a sensation as if lower lip were drawn from both sides to the middle. Afternoon, frequent undefinable pain in heart often interrupted by a pulse-like throb ; feeling as if everything were forced to the heart. E., throbbing pain in heart with occasional pulsations on surface of heart. Sore feeling at apex of1. lung with occasional pulsating sensation, alternating with contractions of lower lip. c. May 31st. 40 dr. tinct., immediately, buccal cavity and fauces rough, as if covered with velvet, for some h . II a.m., when walking sore feeling in apices of both lungs with transient chilliness, soon afterwards slight pressive headache, increased by treading roughly. Lower lip feels contracted.-June ist. 50 dr.; soon, uncommon feeling of coldness. After 1 h. throbbing like strong pulsations in heart, middle of chest, and apices oflungs. This throbbing consisted ofseveral beats in rapid succession, ceased for 5 or 10 m., and then recurred in another place. Forenoon, when making a journey of several miles felt when walking hot feeling in chest, belly, and thighs, with the prickling feeling already described. After the hot feeling had ceased for h., he had a severe sore feeling, pressure and tension in chest, and the pulsating throbbing in apices of lungs. Involuntarydeep breathing while walking, yawning with relief. The sore pain was sometimes dull shooting, often slightly boring, the seat was often only in pleura and pericardium ; sometimes it was felt deeper in lungs and heart with several stronger heart's beats. Tensive pressive pain now in the 1. shoulder, now in finger-joints of 1. hand and in r. hip, lasting intermittingly till e., when it disappeared. Almostravenous hunger. The chest symptoms became gradually worse, the sore pain became burning and frequently changed its seat, but was chiefly in heart and lung apices, with desire to draw a deep breath and cough. Cough bad e.; roughness of trachea causing frequent cough. 8 p.m., cold feeling without shivering. Headache after drinking beer. I a.m., woke up by cough, could not get to sleep again till 6 a.m. on account ofthe sore feeling in lungs and cough and the pressive headache ; slept restlessly till 7. -2nd. The sore pain, especially in the apices of the lungs, continues, with dry cough and VOL. II, 19

hoarse voice ; occasional obtuse stitches with throbbing in heart which he thinks he hears but could not feel with his hand. 10 a.m. , when writing, severe chill soon followed by hawking and short cough kept up by rough feeling in trachea ; head confused and much mucus in nose. 11 a.m., soft stool preceded by griping about navel ; this occurred twice in afternoon. All afternoon chilliness along with above symptoms. 8 p.m., when he went to bed chilliness, especially along back, with thirst. After h. dry heat of head and red face while the rest of body was cold, afterwards heat became general and lasted till midnight, when sweat of upper part of body came on and lasted till 5 a.m. Sleep often disturbed by cough, pressive throbbing headache, and pulsating throbbing of heart.-3rd. Headache continued, tongue furred white, dry, and sore. Some mucus brought up by coughing, it was greenish yellow and sweet like liquorice. Aftereach fit of coughing a burning sensation for some time. The cough was kept up by persistent irritation in bronchial tubes and larynx and made the soft palate painful so that swallowing was difficult ; beer aggravated the symptoms. In e. more of above expectoration with the cough.-4th. On waking head confused, voice hoarse, throat rough. Speaking and swallowing increased pain in soft palate. Expectoration as yesterday. Noon, little appetite, white tongue. Afternoon, constant chilliness and thirst. E. , increased chilliness with dull throbbing stitches in heart and soreness in middle of chest ; hard stool. Before going to sleep rigor with heat of head for h., followed by dry heat and sweat lasting all night with relief of symptoms. Urine red and scanty.-5th. Hoarseness all day, expectoration increased, viscid, and moist. From m. till noon persistent pain in heart. N., frequent cough with expectoration. M., profuse sweat.-6th. Hoarseness continues ; cough with expectoration, the latter increased, is in lumps and has a grey colour. The expectoration comes away more easily and the chest symptoms are slighter. The pulsating throbbing is seldomer, but suffocative feeling, and as if thorax were too narrow, continues till e.; then chilliness, and at n. sweat with relief.-7th. Hoarseness less ; chest tight like suffocation. Cough continues, but less fatiguing ; expectoration easier. E., aggravation after beer, consisting mainly oftightness of chest and more frequent cough.-From 8th to 16th all the symptoms, except cough and expectoration, gone. The fits ofcoughing mostly m. and e. with expectoration of lumps oftough mucus.- 18th. Pressive pain, swelling and redness ofbig toe like gout, not very violent, and lasting 4 d.-22nd, m. , 60 dr. caused roughness in mouth and shooting and feeling of a crumb behind larynx.-23rd. 80dr., white furred tongue ; smell from mouth as from disordered stomach ; roughness in mouth and fauces, with retching and feeling ofa crumb behind larynx ; frequent dry cough, rarely bringing up yellow, disgusting sweet mucus. On going uphill dyspnea and sore feeling in apices of lungs. On waking in m. white tongue and sour smell from mouth.-24th and 25th, 100 dr., 26th, 120 dr., caused the same symptoms in aggravated intensity, which continued to be felt till 6th July. (Ibid., 534.) 7. Dr. LACH, æt. 36. Feb. 18th, 10 p.m., 5 gr. cocc. cac. in 3ss hot water. Immediately dryness in pharynx, making him swallow

constantly, with slight scraping.- 19th, m., slight pressive pain from temple to crown, which went off after walking. 8 p.m., slight burning in throat. Took 5 gr.-20th . Woke at 6 a.m. with severe burning along urethra and intolerable tickling in its orifice. After passing clear, straw-coloured urine, the burning and tickling went off, but the latter returned during d. before each micturition. More frequent urination . All d. disagreeable rough feeling in throat, feels furry; voice hoarse when he had not spoken for a long time, at first always hoarse, but soon became clear. On attempting to hawk, burning in throat.- 21st. Woke twice at n. from dry cough ; great burning in throat relieved by drinking cold water. 6 a.m., woke with cough, which intermitted for minutes, was at first barking, clear and dry; later some viscid mucus was expectorated with so much difficulty that it brought on vomiting several times ; at same time sore feeling in throat and pressive frontal headache. The cough was relieved by rinsing mouth with cold water and drinking a few mouthfuls, which mitigated the heat in throat, but this returned immediately on drinking a little warm milk. Tickling in orifice of urethra like yesterday ; micturition rarer, urine turbid and yellow. No stool yesterday or to-day. 22nd, 6 a.m., cough like yesterday ; it troubled him all d. 3 p.m., 1 h. after dinner vomited in consequence of the continued cough ; after this cough ceased ; expectoration moderate and viscid. Twice before urinating tickling in urethra anteriorly, as if pricked repeatedly with a needle. Fulness of abdomen, as though he had eaten too much. Afternoon, a firm, dry stool ; great laziness, ill-humour and irritability.-23rd. Dry cough. -24th. Cough rarer, expectoration easier, vomiting of whitishyellow mucus; little appetite for 3 d. No stool since 22nd. E., 5 gr.- 25th, m., cough with easy expectoration of mucus mixed with viscid strings ; pressure sure in throat ; no appetite for breakfast ; great sexual desire on waking.-26th , m., hoarseness, with much mucus in throat compelling hawking, which brought away thick, viscid mucus. Forenoon, some fits of coughing. Afternoon, disinclined for anything, lazy, prostrated and weary. E., pain in thighs, as after a long walk.- 27th and 28th. Cough as before until II a.m. Voracious appetite for dinner that was soon satisfied ; hoarseness. E., 5 gr.-March 1st. Could hardly speak for coughing in warm room. In bed the cough lasted from 2 to 3.30 a.m. It was dry and left a sore feeling in throat, with heat and some burning. On waking in m. creeping in crown, making him scratch. Itching in orifice of urethra. Forenoon, firm, unsatisfactory stool. I h. after dinner a copious pappy stool with much flatus . E., 5 gr.-2nd. Hoarseness with hawking up ofmucus. E., 5 gr.-3rd. Pressive frontal headache at breakfast. Violent cough with frequent expectoration ofmucus and constant tickling along • to bifurcation of bronchi ; feeling as if mucus moved in trachea, causing tickling. During d. frequent cough with expectoration ; metallic and pappy taste. E., great thirst and desire for beer ; after drinking a glassful went to bed with headache all over head, great exhaustion, no sleep before midnight.-4th. Woke at 6 a.m., very irritable ; frequent cough during d. The next 3 d. the cough continued with varying degrees of intensity. Expectoration increased, causing much hawking

of mucus.-8th, e., 10 gr.-9th. Anorexia. Afternoon, slight drawing pressive pain in tendo Achillis of1. leg,only felt when walking or stretching foot ; no pain when touched ; the tendon could be pressed and moved from side to side without increasing pain. 6p.m., toothache in hollow root whose crown had been broken off a year before ; tooth very sensitive to touch.-roth. At n. dry cough for hour, excited by tickle in trachea. M., loose cough with easy expectoration of mucus by hawking. The pain in tendo Achillis makes him limp when walking ; must put down the foot turned outwards and must often stop to ease the pain. Cough as before ; much thirst.- 11th, m., renewal of toothache, which lasted till 10 a.m. The pain in tendo Achillis so severe he could not walk; it is tender to touch ; going upstairs is verypainful. -12th. Toothache all d. Pain in tendon rather less; loose cough, hoarseness.- 13th. Toothache so bad ; had the tooth drawn, felt pain in the hole left by tooth all d.; the bleeding lasted long ; pain ceased in e. Cough slight and loose ; hawking ofmucus, m.-14th, 15th, and 16th . The pain in tendo Achillis gradually abated, but still has some pain when walking ; when he moves the foot up and down and puts finger on tendon feels a creaking, as if the tendon were too dry ; periodical recurrence of cough and hawking of mucus upwards, m . (Ibid. , 540.) 8. Dr. J. O. MÜLLER.-March 22nd, 10 a.m., 30 dr. 3rd dil. h. after dinner. On lying down flatulent disturbance in abdomen, loud rumbling in bowels, compelling him to change his position frequently. This was relieved by discharge of flatus but never quite left him all the time the proving lasted. The stool occurred every day at the same hour (4 p.m. ) with tenesmus, slight burning, and protrusion ofpiles, the grumous fæces were enveloped in mucus and were evacuated slowly. The urine, as a rule, was passed copiously every h., was very pale, and had an alkaline odour. In e., in stomach and small intestines feeling of heat ; they seemed to be surrounded with warm water, and at same time shortness of breath and oppression of lower part of chest. N. restless, had to get up to urinate after midnight and again about 4a.m. After the first wakingfelt a kind ofburning drawing in condyle and joint of 1. elbow that kept him long awake. In m. perspiration in legs and feet.-23rd. Disagreeable feeling of hunger, must eat much and often, and the unusual quantity of food did not oppress him. Increased urinary secretion ; flatulent symptoms and grumous stools as before. Unusual cheerfulness and freedom of mind even during the fulness and pain of head with increased heat and stupefied sensation. N. restless and many dreams, could not sleep after 4 a.m.-24th. Urine not so copious but still more than normal, but without increased thirst. Dull pain in r. renal region to the end of the proving. Forenoon, burning drawing in spleen spreading up to 1. side of chest, frequently occurring with jerking stitches ; along with this a peculiar tensive heaviness across shoulders and lower part of nape. Afternoon, violent fits of sneezing with burning as from pepper in nostrils. Three fits of sneezing came next day at the same hour, the burning in nose remained the same. At n. woke with burning drawing in l. hypochondrium relieved by application of warm hand.- 25th. Only the gnawing hunger, the

rumbling in bowels and irritation of anus during stool . E., the stupefying fulness and pain in head. Sleep at n. full of dreams and restless. The next 4d. had the symptoms of stomach, bowels and urinary organs as before, after that was in his usual health. (Ibid. , 559.) 9. a. T. A. ScHWEIKOFER, surgeon, æt. 40.-May 18th . 10 dr. tinct., flat, disgusting taste, increased secretion of saliva, tasteless eructation. After I h. 2 dull stitches in rapid succession in stomach and cæcal region. After dinner uncomfortable humour lasting till e. The disagreeable taste, metallic in character, lasted all d.-19th. 20 dr. ; immediately, slight burning and hot feeling in mouth and throat ; increased saliva with constant desire to spit along with the metallic taste. Hunger soon after eating. Afternoon, slight griping in belly with frequent ineffectual urging to stool.-20th. On waking m. some griping in belly, going off after stool. 9 a.m., 40 dr.; immediately, metallic taste, salivation, hunger, pain in stomach, griping in belly, diarrheic stool ; confusion of head in crown.- 21st. 80 dr., immediately burning and heat in œsophagus and mouth, metallic taste, salivation, hunger, and stomach-ache, sensitiveness of pit of stomach and pressure there ; tasteless eructation ; itching, smarting, drawing in groin and pubes, in prepuce and glans, instep and toes.-22nd. 100 dr. , on waking, m., slight bellyache, thereafter retching with nausea and salivation ; metallic taste, stomach-ache and flatulence. Coldness in stomach as if a cold wind blew in it. Afternoon, constant slight griping in belly beginning in stomach and spreading to cæcal region, coming and going in fits ; hunger, urging to stool, pains in loins and sacrum.- 23rd. 320 dr. , great flow of saliva, nausea, retching, metallic taste, hawking of mucus ; expectoration of yellow sour mucus ; tasteless eructations, feeling as if uvula were too long, causing constant hawking ; itching, smarting, and drawing on and betwixt toes ; griping in belly; drawing and forcing pain in hip, back, loins and sacrum. Emission at n.-24th. 640 dr., great retching, salivation and metallic taste ; burning and hot feeling in gullet and mouth ; later, confusion of head, especially on top. Betwixt 6th and 7th ribs first r. then l. transient stitches ; increased secretion of urine ; tension, drawing and tearing in r. shoulder. When walking, e., great confusion ofhead,especially on top; hunger b. ; several 27th. copious 45 gr. 6thloose trit.,stools. after Inh.3 metallic d.allthesetaste, symptoms greatwent flowoff. of saliva ; 2 obtuse stitches in rapid succession, beginning in lumbar and ending in cæcal region ; confusion of head at top ; distension of abdomen and sensitiveness of scrob. cordis, especially when touched ; spirits depressed. E., metallic taste when drinking beer and smoking. -25th. Woke with griping in bowels, relieved by diarrheic stool. During d. out of spirits, constant metallic taste ; hunger soon after eating ; 3 loose stools ; palpitation causing anxiety for some m.; expectoration of yellow, sometimes reddish, mucus of sour taste.-29th . 50 gr. 5th trit, metallic taste limited to tip of tongue ; slight burning in mouth and throat ; hawking of mucus and tickling in larynx, followed by 3 short fits of coughing. Frequent fine stitches between 1. 5th and 7th ribs, going off on inspiring deeply, returning during expiration. Pains in loins and sacrum.-30th, m., emission. After

waking, 2 copious stools. All d. drawing and tearing in r. shoulder and axilla extending to forearm and index. Rumbling in belly with lumbar and sacral pain. Betwixt 5th and 7th ribs slight burning and shooting, first 1. then r.; hunger. Afternoon, frequent hawking of mucus. Full feeling in abdomen, chiefly in region of bladder ; tension and drawing from lumbar region to rectum ; on flexing both feet, on ankle and inner surface of calcaneum pain as after a sprain. Frequent urging to stool without evacuation.-31st. Slight metallic taste and distension of abdomen, with repeated urging to stool without evacuation.-June Ist. 50 gr. 4th trit., immediately the well-known symptoms, salivation, metallic taste, burning in throat, hawking of mucus, afterwards pain in loins and sacrum, tickling in larynx followed by short cough. E., urging to stool and copious evacuation.-2nd. 50 gr. 3rd trit., immediately disgusting bitter taste, tickling in larynx with short cough. In 1. temporal region obtuse shooting pain for some m., relieved by pressure, but when that is removed returning instantly. E., lumbar and sacral pain.-3rd. 50 gr. 2nd trit., immediately salivation and bitter taste, griping in bowels, sensitiveness to pressure of scrob. cordis and all abdomen, cross humour ; itching and smarting on prepuce and glans ; dislocative pain on bending fore part of foot.-4th. 200 gr. Ist trit., immediately great flow of saliva, followed by forcing pain in loins and sacrum ; transient oppression of chest, followed by uncommonly cheerful disposition. All d. frequent ineffectual urging to stool, followed by 3 stools, with relief to backache. Frequent tickling in larynx and short cough ; itching in nose with repeated attacks of violent sneezing.-5th . All symptoms gone except itching and burning of prepuce and glans and pain in foot. (Ibid., 562.) 10. a. Mrs. SCHWEIKOFER, æt. 42.-April 29th. 100 dr. 6th dil., soon nausea with spasm in stomach and hunger, which recurred the next d. May Ist. 100 dr. 3rd dil., disgusting flat taste, nausea, sensitiveness to pressure of gastric region, especially scrob. cordis. Joyous disposition; feeling of emptiness of stomach ; urging to stool with hard evacuation. These symptoms lasted next d.-4th. 100 dr. Ist dil., nausea, retching, hawking of mucus, metallic taste, flow of saliva, retching and constriction in throat proceeding from stomach up œsophagus, mucous discharge from vagina preceded by tearingforcing pains in groins, bladder, pudenda.-5th. Same symptoms. Menses 3 d. too soon, more copious, blood black and thick. b. May 13th. 40 gr. 6th trit., immediately nausea, disgusting flat taste, salivation, empty feeling in stomach. E., lumbar and sacral pains.- 14th. 40 gr. 5th trit., same symptoms.- 17th. 40 gr. 4th trit., same symptoms, and besides forcing in bladder and pudenda with mucous discharge from vagina.- 18th. All symptoms gone.- 19th. 40 gr. 3rd trit., nausea, retching, salivation, empty feeling of stomach, hunger ; great sensitiveness to pressure of scrob. cordis ; later spreading all over abdomen with shooting drawing pains in groins, bladder, and pudenda, compelling her to go to bed.-20th, 21st, and 22nd. These symptoms gradually went off; the stools were uncommonly firm.-23rd. 40 gr. Ist trit., nausea, salivation, retching, burning in fauces, empty feeling in stomach, discharge of inodorous

Aatus, sensitiveness of scrob. cordis, irritability, digging, tension, forcing and drawing in bladder, pudenda and groins.-24th. Menses came on 7 d. too soon, blood copious, black, and thick. The menses lasted a week, and all the symptoms disappeared. (Ibid. , 566.) 11. A. RUDIGER, a boy, æt. 15.-May 22nd. I gr. C., only disgusting taste.-23rd. 10 gr.-24th. 15 gr., metallic disgusting taste, retching, salivation, nausea and stomach-ache.-25th. 20 gr., confusion of head, 2 loose stools.-26th. 30 gr., continued retching ; feeling as if a thread hung down œsophagus, with constant hawking of mucus ; metallic taste ; stomach-ache, with sensation as if a large ball were there. Later, violent griping in bowels and headache. For some d. afterwards had confusion of head, tiresome metallic taste, stomach -ache, griping in bowels, diarrhea and faintness, so that he had often to go to bed. (Ibid., 571.) 12. a. Dr. C. WACHTEL.-March 30th. I h. after breakfast, zij 6th dil. I h. after dinner, forcing in sacrum spreading forwards and downwards to bladder, and lasting h. E., sensation as if a side incisor was seized by cold fingers and forcibly drawn up.-31st, forenoon, some transient stitches in 1. clavicle. Afternoon, acute penetrating stitches near 1. nipple, and dull stitches between shoulders, which spread forwards in a radiating manner. Later, sensitiveness of lower row of teeth as though they were longer. E., pressure on chest, followed by ulcerative pain in cardiac region ; slight hoarseness, scraping in throat.-April 1st, forenoon, frequently recurring throbbing shooting in both legs ; this pain often ceased suddenly and reappeared in l. upper half of chest. Afternoon, tickling and itching in 1. meatus auditorius, frequently recurring till e. along with pressure in concha.- 2nd. Itching in prepuce and 1. meatus auditorius. 3rd, afternoon, when sitting, violent twitching and boring stitches in rectum, which suddenly passed to neck of bladder, then in the course of the ureters to kidneys. E., for h., continued stopped feeling of both ears, with pressing forcing in meatus auditorius. Some of the symptoms lasted till 8th, especially the stitches in 1. half of chest, which were always excited or aggravated by quick walking. The cough was inconsiderable, came The in short fits with slight expectoration of grey globular mucus. quantity of urine was not increased, but the urine for some d. was darker, more tinted, and smelt like assafœtida. b. May 19th. 10 gr. 3rd dec. trit., soon ebullition of blood to head, with pressive pain in orbital regions, with teeling of flatulent distension of stomach. No appetite for dinner. Afternoon, when sitting, fine stitches in r. half of chest along sternum, soon followed by fits of coughing, with expectoration of easily detached grey, gelatinous, globular masses of mucus.-20th. Towards e., hoarseness, with scraping in soft palate.-21st and 22nd. Stitches in chest, and early waking m. -24th. Pressure betwixt scapulæ, which gradually extended to sacrum and fixed itself in renal region, and frequently recurring tightness of chest, lasting till June Ist. c. June 8th, forenoon, 10 gr. 2nd trit. Soon, feeling of distension of stomach. Later, several violent fits of sneezing, leaving roughness and scraping in fauces as from highly spiced food. Afternoon, dyspnea,

increasing towards e., with occasional stitches in l. upper half of chest -9th. Woke early with oppression of chest, going off after breakfast, but soon returning and occasionally troubling him for several d. a. June 15th. 10 gr. Ist trit., after a few m. inclination to vomit; fit of coughing lasting th.; expectoration of much mucus. Afternoon, frequent urging to urinate. (Ibid., 572.) 13. a. Dr. F. WURMB.-Feb. 17th and 18th, then from 21st to 28th, and from March 6th to 11th, always at 5 p.m. a teaspoonful of tinct. -Feb. 18th. Almost all d. drawing in teeth on 1. side. E., frequent sneezing.- 20th, 7 p.m., attack of tickling cough, lasting 5 m., and ending with expectoration of mucus.-21st and 22nd. Frequent cough with mucous expectoration.-23rd. Immediately after rising m. feeling of roughness in the throat, with fit of coughing lasting nearly h., sometimes so violent as almost to cause vomiting ; expectoration of a large quantity of viscid, sticky, white-of-egg-like mucus. Cough aggravated by heat of stove, relieved by stopping in cool room. During d. frequent coughing up of mucus. Diminished excretion of urine. E., feeling of a foreign body betwixt eyes and lids.-24th. Coughing up of easily detached mucus.-25th, noon, drawing in r. molars ; feeling as if tarsal edges were swollen ; very importunate sexual desire ; frequent cough with mucous expectoration.-26th. Chilliness more or less all d.; moderately increased quickness ofpulse ; itching in legs, compelling scratching.-27th. Frequent micturition, almost every h. in afternoon ; itching in legs.-28th and March 1st. Frequent and copious discharge of pale yellow urine.-2nd, m., great sensitivness ofteeth on rinsing mouth with cold water. Forenoon, drawing in l. molars. Disagreeable warmth in glans penis and 1. testicle. Discharge of pale urine in larger stream. I p.m. , very violent twisting pain in neck of bladder lasting + h., not relieved by micturition or discharge of flatus ; disgust at food. 9 p.m., rigor all over body for h.; pulse 100. Sleep disturbed by many vivid dreams ; woke at 3 a.m. with dry heat and restlessness ; alternation of sleep and waking. Towards m . general profuse sweat. 5a.m., seminal emission.-3rd. Soon after rising pressive pain in 1. temple, sometimes extending to 1. eye, and lasting about a d. M., pappy taste. Noon, soon satiated. E., tiresome drawing in r. deltoid muscle, rendering it difficult to raise arm. -4th, 5th, and 6th. Sometimes itching on legs.-7th, forenoon, sudden drawing in r. lower incisors ; pressure in 1. eyeball. After dinner extreme weariness is felt lasting 2 h. in the room, going off at once when he went out ; sleep disturbed by frequent waking owing to vivid disagreeable dreams.-8th, m., great sensitiveness of teeth to cold water. Forenoon, same pain in r. wrist. Afternoon, itching in legs and in fingers of 1. hand. Betwixt 5 and 7 p.m. 3 discharges of urine in thick stream.-9th. Slight itching in legs and fingers of 1. hand.- roth. Frequent expectoration of easily detached mucus. 5 p.m. , painful stitch from anus through urethra.-11th, 12th, and 13th. Gradual disappearance of all the medicinal symptoms, except the cough with easily detached mucus and sensitiveness of teeth to cold water and cold air. b. From March 23rd to April Ist (with exception of 2 d.) he took

every day at 5 p.m. 2 teaspoonfuls of undiluted tinct.-March 23rd. Immediately urging to urinate. 11.30 p.m., woke from tickling in larynx, which caused very violent cough, lasting 10 m., with copious expectoration of viscid mucus.-24th. Woke with feeling of coldness of feet and sweat on the upper half of body. On rising, pressive shooting pain in lower lobe of r. lung. This pain was very violent, especially when breathing deeply ; not affected by movement. Sneezing, which it provoked, was impossible on account of the violent pain ; it lasted till noon, and then suddenly departed. Afternoon, frequently coughs up easily detached mucus.-25th. Immediately after dose, dry feeling in throat lasting 2 h. Frequent coughing up of mucus.- 27th. Immediately after dose drawing in r. meatus auditorius, lasting all e.-29th . Drawing in r. ear, lasting 2 h.; sometimes drawing in l. ear. Sudden drawing in teeth and itching in l. upper arm.-30th . Forenoon, sudden drawing in incisor teeth and r. meatus auditorius. Between 3 and 5 p.m., chilliness, cutting in hypogastrium, and discharge of much inodorous flatus ; the chilliness went off immediately in open air. 6 p.m., feeling of roughness in throat and frequent coughing up of easily detached mucus. 7.30 p.m. , sudden drawing in anterior aspect of r. thigh above knee, in r. big toe and 1. thumb.- 31st. After dinner, chilliness lasting 2 h. 4 p.m., obtuse stitch in lower lobe of r. lung on breathing deeply. E., scraping in throat and frequent coughing up of easily detached mucus.-From April Ist no more symptoms, except sudden drawing in teeth, which occurred occasionally for several weeks. (Ibid. , 579.) 14. Professor VON ZLATAROVICH took from Feb. 18th to July 7th, with the exception of a few days, every m. 10 gr. of Ist dec. trit.- Feb. 18th. Slight scraping in throat.-19th. After the dose and for some time after breakfast disagreeable sweetish metallic taste ; repeated sneezing ; frequent discharge of flatus. Noon, pretty severe, shooting, tearing pain on inner side of shaft of r. tibia ; slight burning in anus.-20th. In m. after dose disagreeable taste; repeated sneezing ; discharge of much flatus ; sensitiveness of crown. Forenoon, transient burning under sternum.-21st, 22nd, and 23rd. Frequent coughing up of mucus.-24th, e., severe pressive and drawing pain in lumbar and sacral regions.-25th, m., pain in sacrum, lasting all forenoon, ceasing for a short time, and then recurring. Betweenwhiles scraping pain in shafts of tibiæ and in elbows.-26th. Woke at 5 a.m., wide awake for 1 h., then slept till 7. Rumbling in bowels, discharge of much flatus. From 27th to March 6th frequent coughing up of mucus, alternating with dry, short cough ; occasional burning in legs.-7th, forenoon, occasional transient tearing in tendinous expansion of both forearms ; when that went off similar pain in both legs. Much flatus discharged. Noon, when urinating slight burning in urethra.-8th. Slight crawling in anus.-9th. Immediately after dose, slight moving of flatulence, which was then discharged. h. after breakfast sudden acrid-bitter taste about root of tongue, causing vomiting. For some d. past much mucus from nose. E.,great confusion of head, with pressive aching pain in crown ; burning in skin of forehead, lasting till n.-10th, m., slight coughing up of mucus. Bad

taste after breakfast. All d. slight burning in eyelids ; much mucus from nose.- 11th. Sweat on r. leg ; occasional coughing up of thick mucus ; very severe burning and itching on r. leg.- 12th. Woke early with severe pressive and burning pain in crown for 1 h., went off after a short sleep; severe burning and itching on r. leg. Soon after dose disagreeable taste ; discharge of flatus ; blowing ofmuch mucus from nose ; rumbling in bowels ; groaning in sleep.- 13th, m. , violent itching in legs ; coughing up of mucus. After dose, excessively disgusting taste that remained for some time after breakfast.- 14th, m., coughing up of mucus ; much discharge from nose. Forenoon , very severe pains in corn on r. little toe, making him limp.- 15th, m. , after dose, nausea sometimes amounting to inclination to vomit, with eructation of wind. Groaning at n.-16th. Discomfort in abdomen after breakfast, disagreeable bitter taste, eructation of wind. Noon, after exercise tenesmus in anus.- 18th, m., short cough with expectoration ofthick mucus. After dinner rumbling in bowels. E., pressure in fauces when swallowing saliva.- 19th and 20th. Frequent coughing up of disgusting thick mucus.- 21st, m., great sexual excitement. Immediately after dose transient nausea. Noon and afternoon, repeated attacks of soreness and pressure under sternum.-22nd, m., coughing up of thick viscid mucus ; burning in r. leg ; bitter taste. E., after walking, feet very tired ; burning in soles.- 23rd to 27th. Same symptoms.-28th, m., dry cough. For several d. past painless pimple on back, which now discharges a quantity of thick pus.-29th, m., coughing up mucus ; rumbling in bowels ; disagreeable taste. After rising, short oppressed breathing. For some d. past the front of soles is painful after moderate walking, pain is burning ; when seated changes into hot feeling and gradually goes off.-30th to April 4th . Coughing up of mucus, bitter taste, rumbling in bowels. -5th, m., roughness in throat, sticking together of eyelids. After breakfast, nausea ; inclination to vomit, especially after coughing, which forces water from eyes.-6th. After dose and breakfast discomfort in stomach, and flatulent distension of abdomen.- 7th. Soon after dose pressure in stomach, nasty sweet metallic taste, and slight nausea ; coughing up mucus ; much mucus blown from nose ; slight burning of tarsal edges ; dyspnea ; oppression of chest ; moist secretion between nates and at anus .-8th . Yellow secretion from anus ; coughing of mucus ; discharge of flatus ; much nasal mucus.-9th. After dinner rumbling in bowels ; discharge of wind upwards and downwards ; cough dry or with expectoration of thick mucus. These symptoms lasted the next 4 d. 14th, m., coughing of mucus ; slight burning pain in r. leg. After breakfast very disgusting, bitter, astringent taste, mostly in root of tongue and fauces, all forenoon ; nasal mucus ; frequent short, dry cough ; fatigue of vocal organs from speaking ; hoarseness.- 15th and 16th. Same symptoms, and yellow discharge from anus.-18th. Immediately after dose, pressure and burning under sternum near stomach, lasting h.- 19th and 20th. Coughing of mucus, slight pressure in stomach.- 21st, m. , Aatulence in abdomen ; sore feeling in shaft of r. tibia ; frequent short dry cough. After dinner pinching in abdomen; discharge of flatus ;

COCCUS CACTI . . 299

much mucus from nose.-22nd, m., not refreshed by sleep. Immediately after dose cold feeling and discomfort in stomach ; rumbling in bowels. Forenoon, short dry cough. Noon, after a glass of water sickly, sweet resinous taste, especially at root oftongue ; little appetite. After dinner, flatulent distension and discomfort in stomach ; tearing here and there in long bones.-23rd. Fatigue of vocal organs ; voice rough and hoarse after a little talking ; breathing laboured.-24th, m., cough with mucous expectoration. After dinner, rumbling in bowels.- 25th to 28th. Same symptoms.-29th. A painful lump on crown the size of a large lentil ; in e. still painful but not elevated.- 30th. After dose flatulence in abdomen, discharge of flatus, burning in r. leg. After breakfast pressure in stomach, eructation of air ; much mucus from nose ; a yellow powdery substance on inner border of nostrils. Forenoon, often short, dry cough from irritation in trachea. From May Ist to 5th. Coughing up of lumpy mucus ; roughness and hoarseness of voice ; slight burning of eyelids and skin of r. leg; discharge of flatus.---6th. After waking great tension in 1. cervical muscles, going off on rising. During d. dry, sometimes loose, cough.-7th. On waking fatiguing, painful cough from irritation in larynx and trachea.-8th to 12th. Coughing up of mucus ; bad taste; fatigue when walking.- 15th. After dinner some shooting in head on r. of coronal suture ; painful stitches through brain with impaired hearing.-16th to 27th. Frequent coughing up of mucus ; discharge from nose ; discomfort in stomach.-28th . Drawing and tearing here and there, especially in neck, betwixt shoulders, and in forearms. After dose, rumbling in bowels, discharge of flatus. Forenoon, when speaking tightness of chest. After dinner often transient stitches in r. leg near ankle.-30th, m., roughness in throat, mucous cough. On penis a pustule. Forenoon, several attacks of pressive stomach-ache with nausea.-31st, m., mucous cough ; the pustule on penis discharges fluid on pressure. Soon after dose pressive gnawing in stomach ; sickly taste.-June Ist. Increase of sexual desire ; small sore places on crown ; pustule on penis nearly gone.-2nd to 5th. Expectoration of lumpy mucus ; great discharge of mucus from nose . (Ibid., 582.) 15. R. ScH., medical student, æt. 21.-April 2nd. 10 gr. 1st trit.-4th. Scraping in organs of deglutition, slight constriction in throat. After two similar doses, same symptoms.-23rd. In addition to these symptoms, irritation to cough, eructation and nausea.- 25th to 28th . Cough continued, with relief in e. ( Ibid., 588.) 16. H-, medical student, took every morning for 8 d., at 6 o'clock, 10 gr. Ist trit. Disagreeable, bitter, nauseous taste ; increased appetite ; transient, very painful stiches in both sides of chest ; dyspnea ; dryness of fauces. ( Ibid. , 589.) 17. ADOLPH S-, æt. 25.-Jan. 20th. 10 gr. Ist trit. In 1 h. slight irritating scraping in larynx, causing hawking and coughing.- 21st. Same dose, same symptoms.-22nd. Scraping in larynx and trachea all d.; slight hoarseness e.-23rd. Hoarseness continues ; 10 gr.; all d. scraping in air passages and irritation to cough.-24th, m., urine with brick-red sediment. Repeated dose. After I h. return of

scraping in larynx, slight hoarseness.-25th. The urine passed in afternoon deposits in e. red sediment; this symptom and the hoarseness and dry cough continue till end of month. (Ibid., 589.) 18. W. REIL, æt. 29, in good health.-April 18th, 11 a.m., 5 dr. tinct. in water. 4 p.m. , 5 dr. 9.30 p.m., 5 dr.-19th, 10.30 a.m., 10 dr. Sweetish taste. 12 noon, 10 dr. Sweetish bitter taste, slightly aromatic. 3 p.m., 10 dr. 10.30 p.m., 10 dr. Urine at 8 a.m., ziv, straw coloured. 12 noon, 3v, straw coloured. 3 p.m., 3v, lemon coloured. 4.45 p.m., zij, preceded by urging to urinate. 8.30 p.m., 3v. 11 p.m. , Ziss, preceded by great urging.-20th. Last n. frequent urging,but could not urinate ; frequent erections. 9.30 a.m., 20 dr. Taste bitter, causing nausea. 11.30 a.m., 20 dr. 1.30 p.m., 20 dr. A costive stool. 4.30 p.m., 20 dr. Only frequent urging to urinate. Urine, 3.30 a.m., Ziiiss, with great urging ; urine clear, straw coloured. 7 a.m., urine turbid with much mucous sediment. 9 a.m., zv, lemon coloured and clear. 11 a.m. , turbid, cloudy with mucous sediment. 11.15 a.m., ziv, clear, very acid. 1.30 p.m. , ziv, the urine remained clear for 3 h. 4.15 p.m., 3vss, as above. 5.30 p.m., do. 10 p.m., Ziiiss, do., next morning turbid.- 21st, 9 a.m., 30 dr. Asoft stool. 11 a.m., 30 dr. 1.45 p.m., 30 dr. 9.30 p.m., 30 dr . , frequent urging to urinate sometimes without result. Urine, 7 a.m., 10 Zvij. 11 a.m., Zviss. 3 p.m., viss. 5 p.m., 3x. 8 p.m., 3xj . p.m., zij , urine clear.-22nd, 9 a.m., 50 dr. Ordinary stool. II a.m. , 50 dr., no urging to urinate since 8 a.m. 1.30 p.m., 50 dr., a loose stool. 4 p.m., 50 dr. 8 p.m., great itching at orifice of urethra. 9.15 p.m., 50 dr. Urine, 2 a.m., Ziiss. 8 a.m., Ziij. 12 noon, Zziv. 3.30 p.m. , 3vss. 6 p.m., Zviij. 9.45 p.m., Ziij. Urine clear, acid, after some h. turbid with mucous sediment.-23rd, 8 a.m., 50 dr. 9 a.m., pains in l. hypochondrium as from flatulence. 9.30 a.m., 50 dr. , pains continue, extend to 1. side of back and lumbar vertebræ ; no flatus, no stool . 1 p.m., 50 dr. 2.30. p.m., twisting pain deep in belly on 1. side of spine. 4.15 p.m., 50 dr. From 5 to 8 p.m., repeated attacks of great pressure on bladder and redness of face. 4.30 p.m., hard stool . E., great weariness and yawning. 11.30 p.m., 50 dr. Urine, 4a.m., 3v. 12 noon, Zviss, clear brown colour, after h. showing a cloud, after 2 h. red, jumentous. 2.30 p.m., 3v, rather clearer than the last. 4.30 p.m., Ziiss. 7.30 p.m., Zviij . 11 p.m., ziv. After a short time the clear brown urine was turbid and reddish, with sediment ; slightly acid.-24th . Last n. restless from pains in urinary region and ineffectual straining to urinate. 8 a.m., 60 dr. 9.30 a.m., 60 dr., much painful drawing in region of 1. ureter. II a.m., 60 dr. 2 p.m., 60 dr. 3.30 p.m., a hard stool. 4 p.m., 60 dr. The violent pressure in bladder with constant urging to urinate remained after urinating at 7 p.m. 9 p.m., 60 dr. 10 p.m., 60 dr. All afternoon great weariness. Urine, 8 a.m., Zviss with many mucous flakes ; still acid after 3 h. 12.30 p.m.,3vss. 3 p.m., 3v. 4 p.m., Zij . 7 p.m., Zix. 9.45 p.m. , zij . Urine same as yesterday.- 25th, 8 a.m. , 80 dr. Soon several coughing fits as from tickling in larynx and throat. 9.30 p.m., 80 dr. 10.30 p.m., 80 dr. About noon very great urging to urinate, but has to wait long until urine comes, and its passage was attended

with burning in urethra. 5.30 p.m., 80 dr. 7 p.m., 100 dr. 9.30 p.m., 100 dr. All day painful sensations in kidneys and bladder. Much flatus but no stool. Urging to urinate and has to wait long for first drop. Urine, 8 a.m., Zviss . 12 noon, ziv. 5.15 p.m. , Zviij. 9.30 p.m., 3v. Urine acid, reddish brown, soongets turbid and jumentous. Mucous sediment and mucus suspended in urine. -26th, 8 a.m., 100 dr. 9 a.m., very copious pappy stool. Soon, but not immediately after each dose, dryness in throat, making him cough. II a.m., 100 dr. 1.30 p.m., 100 dr. 5 p.m., 100 dr. 9 p.m., 150 dr. All symptoms as before but more severe. Urine, 8 a.m. , Zvj . 12.15 noon, zivss. 2.15 p.m., ziv. 4.30 p.m., 3v. 9 p.m., zvij ; urine as before.-27th. Took no med. Pain in sacrum and renal region, pressing on bladder, much itching on glans, long waiting for urine to come. Small hard stool at 3 p.m. Urine, 6 a.m., Zvss. 10 a.m., Ziij . 12.30 p.m., zivss. 3 p.m., Ziij. 8 p.m., 3j. II p.m. , Ziij . Urine as before.- 28th. Took nothing. Urging to urinate slight, as also pains in kidneys and bladder. Much latus, no stool. Urine, 8 a.m., Zviss. II a.m., zivss. 2.30 p.m., Ziiiss. 5 p.m., ziv. 8 p.m., 3viss. 10.30 p.m., zvij. The urine first discharged was still reddish and turbid ; the subsequent discharges clearer. E. , lemon-coloured, with threads of mucus and a little sediment. (Hom. Vierteljahrsch., i, 209. ) 19. Two knife-pointsful of cocc. cac. 2nd trit. caused : Urging to urinate, pricking and tickling in orifice of urethra, pain in umbilical and deep in cæcal region, rumbling-shooting in rectum, urging to stool, often in vain, tearing in frontal bone. Urine altered neither in quantity nor quality. (LEMBKE, A. h. Z., xlix, 185.)

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