Chionanthus virginica
автор Richard Hughes & Jabez P. Dake — A Cyclopaedia of Drug Pathogenesy
Volume IV — Appendix
CHIONANTHUS.
CJiiaiantktu nnrgimea, L, Fringe tree. Nat. Ord., Oltacta.
I. Provingj. — Dr. Scudder, in good health, save for some aphasia, took 30 dr. of a strong tinct. at i p.m. *.%o, sensations of contraction in stomach, as if some living thing was moving in it, with uneasy feelings in hepatic and splenic regions, and rheumatic pain in 1. ankle and tarsal bones. 3, unpleasant sensations in stomach and hypochondria have much increased ; feeling like spasm or throbbing in stomach ; uneasiness about sigmoid flexure as if from flatus ; tongue yellow in centre ; pulse morbidly smaller and weaker ; rheumatic pain at carpo-metacarpal joint of 1. thumb. At bedtime evacuation of black, tarry-looking faeces. Slept well. On waking had pain for a short time in spine, from 7th to loth dorsal vertebrae. (U. S. Med. Invest., lii, 56a.)
a. I gave medicine to Mr. G — with about the same result, and to Mrs. N., who found a single dose of 10 dr. produce all the sensations named in so unpleasant a form that she could not be induced to repeat it. In this case there was feeling as if bowels were about to move violently, from the action of a purgative, with the nausea usually associated with such an action ; there was, however, no discharge from the txiwels. (/^.)
- I made my tincture from the bark of the fresh root, just after the tree had flowered, and let it stand for six weeks before decanting. July loth, 1881, 9.30 a.m., I took I dr. of the tinct., after having taken the lax and 6x potencies, one day each, imthout any effect. I continued taking the tinct. each h. during the d., increasing each dose i dr. till 5 dr. were reached, then increased each dose 5 dr. till 25 dr. •were reached, but without any effect whatever, nth. — I began with 30 dr. at 9 a.m., and increased dose 5 dr. each h. till I reached 5j, and took 3 doses of 3j each. I retired at 10, feeling perfectly well. I woke up at 4.10 a.m. on
isth with very severe headache—chiefly in forehead and just over cyrti, etptciaDy I. eye. Eyeballs exceedingly painful, feel »ore and bruised ; cutting, iwiitiiu pains ail through abdomen. I ttimed over and lay vvith my face downward, vhica seemed to relieve the abdominal pains somewhat, and after a while I went to sleep. I woke up again at 8.30, feeling very sick and badly all over ; head venr vsrt ■II over and through it; heavy dull feeling in forehead and drawing or prr*»iag it root of nose. I felt so weak I had to sit down awhile before I could Enoii dressing i never before felt so sick at my stomach. Bitter eructations, great nausea am] retching, with a desire for stool. I finished dressing and looked at my tongue, nhidi was heavily coated and of a dirty, greenish.yellow colour. I started downitain and had a very violent attack of nausea and a great deal of retching before I could ronit. It seemed as though there was a " double suction " in my abdomen, one trying (« force something up and the other sucking it back, till finally, by quite an efTon, 1 vomited a te.-i.cup full or more of very dark green bile, rather ropy, I think, and exceedingly bitter. The bile all came up with a single gush, and I was •" through." Immediately a cold perspiration broke out and stood in beads on my forehead, and I felt very weak. Desire for stool gone after vomiting. I had a sore, weak, bruised feeling all over the small of my back ; felt very weak when standing or moriog about, better sitting or lying down. No appetite for breakfast) but my stomach fdi so weak and empty that I drank a cup of coffee and ate half a biscuit, which relieved to some extent. 9 a.m., am so nervous I cannot keep still, and can hardly vnitt down my symptoms. 9.30, back in lumbar and sacral regions ho sore and weak 1 could hardly walk from the car to the office ; every step seemed to jar my whole body and made my headache worse. 10, have been quiet for | h. and feel soniewhil better j have pressing or squeezing sensation in bridge of nose, sore cuiutrictioc feeling in temples with throbbing temporal arteries. 10.30, just come t'roro stool j the first passed was watery, but the last was more solid in appearance ; stool terribly offensive, like "carrion ;" heavy, all-gone son of feeling low down in hypogastrium ; colour of stool was dark brown, with pieces of undigested food in it. 11.30, jiitt
fot home and feel very badly and weak. My head and back ache considerably, ud feel "played out" generally. i», forehead and cheeks very hot and dry ; radial pulse 114. Chilly sensations darting through body from front to back, causing » sort of shivering or involuntary jerking ; forehead feels like a hot coal of firt to mv hand ; headache in forehead and over eyes relieved by pressing with hand, but 1 cannot bear it long, for my head seems to get hotter from it j am esccedisgly nervous, cannot lie still ) involuntary jerkings in different parts of body. Roof of mouth and tongue feel ver}- dry, although there seems to be the usual amount of saliva present. No thirst at all. I went to sleep about 11.20 p.m., and wm awakened at a for dinner. Could not eat anything ; I tried, but it nauseated me ; could only drink a cup of coffee ; headache worse after waking ; pulse 8K ; head not quite so hot i body feels chilly, and I had a shawl thrown over me : went to sleep tgvt about 3. JO. I was told that, at 4.1 Si my head and face were covered with a. profuic perspiration, and my carotid arteries pulsated very hard and rapidly ; I got up it 5 and bathed my face in cold water, and felt somewhat better, though head and back ache considerably and feel quite sore j eyeballs feel bruised. 6.$o, weak, empty feeling about stomach, which was relieved for a while by eating tome crackers lod drinking a cup of coffee ; pulse still 88. At 8.15 had an action from my bowcbt during stool, griping and cuttingpains in abdomen, about and below umbilicus; itool thin, watery, blackish-brown colour, and very offensive. I retired at 9,30, and h»d to have extra covering thrown upon me, I was so chilly j while my rtwm.matc 1»T without any covering at all. My head feels sore and bruised all over, and the wittll of my back is exceedingly weak, and feels, when I touch it with my hand, at tbougb the skin was all off. I3th.i— I was very nervous and restless last n. after going «o bed J didn't go to sleep till after 11, and woke up several times before daylight, tiith paiiH in head, abdomen, and back -, got up at 8 this m., my head feeling sore and bruised j the bruised feeling seems to go some way into my brain now; every time 1 naove, cough, or laugh, it seems as ifmy head would split open and fly in eroy directioD, my back is not so painful this m. ; I couldn't eat much breakfast ; stool this m. was quite copious, water)', dark brown, and not so offensive a* yesterday. 9.30 a.ra., headache better ; several times this m. I have had attacks of cuttiM o> griping pains in my intestines, in and about umbilical region ; my tongue is lery
irilv coated in the centre with a. thick, yellowish fur, tip i^ light red, and on each
! of tip there are several little places that look as though blood was about to ooze
from them ; tongue feels drawn and shrivelled up in centre. 4.30 p.m., the only
^iiiptom this m. was a dull, sore, aching feeling in umbilical and iliac regions, occa.
nonally changing for just a m. or so to a severe griping, relieved somewhat by the
enusiion of flatus. My face has a yellowish appearance ; from the outer to the inner
caotbus there is a reddish-yellow streak about J in. wide in whites of both eyes ;
blood-vessels of sclerotic coat are very much enlarged and distinctly visible, i+th,'^
I stifFered considerably after 5 p.m. yesterday and last n. with the pains in my abdo-
P>«1, and they are more severe this ra. than yesterday; it feels just like a stnng tied
«n a •« slip-knot " around my intestines in the umbilical region, and every once in a
•"while it was suddenly drawn tight for a minute or so, and then gradually loosened j
•tool this m. was very thin, watery, and rather flaky, flaky portion was dark yellow,
"ui<J portion dark green, with a light green foam or froth on top, streaked with a
•"hite, mucous-looking substance J flatus and feces passed together j some pain in
*****els during stool, and a hot, scalded sensation in anus, which lasted 15 or ao m,
*^<?«" stool ; during stool cold perspiration broke out on forehead and back of hands t
"oofc. quire a while to pass stool, and then only a small quantity passed ; eyeballs feel
•rTJis-ed and the whites have a yellowish cast all over, though the "bands" are still
''^ry distinct; my skin is quite yellow to-day, and I feci very much fatigued gene.
•^"y. i5ih. — Stool about natural this m. ; same feeling in abdomen, though not so
*^^ct"«; no new symptoms. 16th.— The only thing unusual which I noticed to.day
'?'*s_ tfce passage of considerable offensive flatus ; a greater quantity after retiring than
i**^»*»g the d. I noticed no more symptoms after that n. (J. Z. Lawskr, n. Am.
7t»tu M», tfHom,, May, 1883.)