Aesculus hippocastanum
автор Richard Hughes & Jabez P. Dake — A Cyclopaedia of Drug Pathogenesy
Volume I — Main text
iESCULUS HIPPOCASTANUM*
Micnhs Hifypoioitamm^ L« Horse-chestnut. Nat. Ord., SapinJaci^,
I. Prffuings. — i. Dr. BucHMANN, at. 40, sanguine temperament. Easily chilled, but in good health, a. Sept* ij^ 1^57- — At 3 p*m,, chewed and swallowed gr. 30 of fresh kernel. Tasted like aloes. In 5 m. contractive pain in throat, nausea, tightness of chest ; hot feeling n chest with cold risings \ sweetish taste ; hawking of thick mucus ; frequent eructation ; short cough, increased by swallowing and breathing deeply ; violent burning in throat with raw feeling there. Voice became hoarse i speaking brought on the cough. Dry feeling
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and sensation of heat in nose, especially point, as when coryza is supervening. Pains in n scapula and in I. side of chest, increased by inspiring. Flying heat in K side of face. Itching in anus, L. arm and hand become strikingly warmer, and feel as if swollen and heavier. Thin mucus from throat and (frequently) nose. After 2 h, two moderate stools, and symptoms disappear*
k Oct. 4, 9 a,m,, same dose. In a few m. nausea ; burning and scraping in throat, exciting cough i tightness in chest, pressure in pit of throat, as if something had stuck there which needed expulsion. Raw feeling in chest, and throughout nasal cavity ; burning \n nostrils and internal canthi. Sudden stitches throughout chest ; frequent nasal dciluxion ; rheumatoid pain in r. scapula, itching in anus, shoots in orifice of urethra. In 2 h. symptoms had gone. ( Horn. Fierteijahnchnft^ x, i.)
- Mrs. BucHMANN, set, 29, brunette, choleric temperament^ nervous and sensitive, a. Took same dose Sept. 29th, 2 p.m. In a hw m. nausea, retching, tightness of chest ; raw feeling in throat and chest \ heat in chest with cold rising, as after taking peppermint drops ; hawking of thick, afterwards watery, mucus \ pain in chest as if stone lay on praecordia, ijicreased by deep inspiration ; palpitation in frequent attacks j twitching from chest to L shoulder ; frequent eructations of wind with water. Burning like fire on swallowing, and whole throat was excoriated and constricted. Pain now in hypochondria through to back, especially on inspiring ; chilliness and goose-skin j burning in palms and soles. At each eructation desire to go to stool. Within i h. three moderate stools. Feels very weak and extremely ill, totters when she walks, has pale, miserable appearance. Pains in sternum, as if a piece were torn out of chest j pains in small of back and cramplike feeling in bowels, with urging to stool, ending in a fourth evacuation (2 h,). Flying heat and redness of 1. side of face ; yawning and stupefying sleepiness i pains in chest and abdomen alternately ; eructations relieve. Slept well ; next m. liquid motions preceded by griping,
b. Oct. 8th, 9 a.m., took gtt. v of tinct. Burning of throat and tightness of chest j retching; eructations and flow of water into mouth ; tearing and jerking in r. arm, which felt paralysed and useless. Periodical palpitation \ formication in nose ; weariness. She falls asleep, when sitting, for ^ h. ; on waking cannot recognise what she sees, knows not where she is, or whence come objects about her. Burning in L cheek. Immediately after, sleep for another \ h. On waking, same dazed state ; feeling as if board were on head ; rigor for 10 m., cannot get warm, constant yawning j violent formication in nose and fauces j sensation as if air breathed in were colder ; severe fluent coryza. On r. side of chest feels lung moving painfully up and down ; at each inspiration, griping in bowels ; pain extends from bowels to small of back. Pale, miserable appearance i feels like to taint i tottering gait. Symptoms gone in 3 h,
r, June 4th, 1858, took gtt. x. Burning in throat and stomach j great flow of water into mouth j severe periodical palpitation with great anxiety ; cutting stomach-ache \ constant yawning and weariness ; tearing pain in back, r. side, and shoulders. Again on respiration feels r. lung move up and down j pressing downwards in abdomen, cramps
in bowels ; constant jerking in r. arm ^ rigor as of ague For | h* Afterwards^ four loose stools within ^ h. i pains in small of b»ack from abtlomen i severe coryza ^ constant shooting and raw pain in throat ; motions preceded by pinching in bowels. Later, stool of mixed character, with raw feeling in anus ; disposition to sneeze i shooting pain in nose ; weight tn eyes i weariness ; nausea j inclination to sleep. Looks ill. Duration of action 4 h. (Uid.)
3, Miss W, B— , 2tt, Sly sanguine. Oct, 2nd, 2 p.m.^took gr* 40 of kernel. Much raising of mucus, burning in throat, nausea, violent vomiting; aching in forehead, with feeling in it as during cold in head. LViscid mucus continued to be raised periodically ; feeling in nose as ifter a pinch of snufF; heat in whole body; sensation in head as if intoxicated ; tightness of chest ; laboured breathing ; heat in head and eyes ; mucus in throat excites cough ; eructations, preceded by flying heat ; in 2 h* several thin stools. {Ihid.)
4* Miss N, N — , «t. 33, sanguine. Oct, 2, took gr. 40. Con* tractive pain and burning in throat ; rigors ; periodical tightness in pratcordia with laboured breathing, later twisting there ; pain in throat as if burnt ; fatigued feeling as from long walk ; rush of water into mouth ; fluent coryza, with twisting sensation in front part of nose ; pressure as from stone in pit of stomach ; frequent eructations ; inward cheerfulness and placidity. {Ihid.)
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Mf, R, H — , set. 48, pale, black hair. Sept. 30, 8.30 a.m.^ took gr. 40, Rising of thick mucus ; heartburn for 4 h. ; afterwards, tickling in throat causing cough for i h., with occasional eructation. Frequent call tocxpectorate mucus, which becomes watery ; inclination to swallow; some urgency to micturition; sensitiveness of nasal mucous membrane to respired air, which causes feeling of coldness in nose ; fluent coryza ; frequent expulsion of flatus ; stitches in I. side. Nasal mucus becomes even more watery, inspired air more felt ; in 3 h. after taking drug severe fluent coryza, after which symptoms gradually subside. {Ibid,)
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Mr* E. B — , aet. 22, blonde and sanguine. July 4th, 7 a.m., took 30 drops of tincture, Bitter burning taste, astringing mouth and gullet ; occasional eructation ; aching and rumbling in stomach ; tickling in larynx, causing cough with mucous expectoration ; coryza, with cool feeling in nose on inspiring ; burning in mouth and gullet ; water flows into mouth ; shooting pain in sternum ; aching in stomach extends downwards ; shooting in r. side above hip, deeply seated ; headache over Leye ; lachrymation, quivering of lids ; flickering before eyes. In i^ h, inclination to vomit j thence gradud decline of symptoms, {Ibid,)
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a, Mrs. T — , aet. 54, nervous temperament. July 25th, at 745 a.m., 30 drops of tinct. Immediate nausea ; in 15 m, burning in throat, of varying severity; eructation- In 15 m, more fulness of stomach ; distension of abdomen, going off in perspiration ; confusion of head ; dryness of larynx. Vision clearer than usual. At n., jerking in r, eye ; formication in front of temple ; burning in mammae. At 2 p.m. flatulent discharges with griping. Usual stool did not occur.
b, July 29th^ 10 a,m.| same dose. Same symptoms, with (at 11}
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neadache over r. eye and leucorrhcca, also drawing in r. nostril as in violent coryza, {Ibid,)
8, Dr. C. W, BovcE, Aug, 24th, took 10 gr. of i, trit. Nausea immediately ; and constant desire to swallow, with feeling of dryness and stiffness at throat when swallowing. 28th, ir a.m., same dose. Nausea again, constant ^ with dryness and roughness of throat as from taking cold* At 5 p.m., 10 gr. more. For 2 d, after almost constant inclination to stool, without any, or with very slight, evacuation, Sept. 1 2th, 9 a.m., same dose, Stck feeling in stomach all d., but increased appetite. At 4 and 8 p.m., repeated dose. With nausea, salivation* and metallic taste, dryness of throat, and sense of dryness and itching in rectum, with stiffness of skin and adjacent cellular tissue, continuing several d, 24th, 3 p.m., 10 gr, ** Diarrhoea of ingesta/' For several d. following sensation as if mucous membrane of rectum was thickened, obstructing passage of faeces. Dryness of passage coincided, ending in a moist secretion ; and soreness, with feeling as if something would pass off. Oct, 3rd, — Same dose. Dryness of throat and rectum. 4th. -^ Same. With dryness, tickling scraping feeling of laryngo-pharyngeal mucous membrane. Nose stuffy, as from catarrh, with sneezing. 5th, — Dose at 9 a.m. With throat symptoms of yesterday, stiffness also. After second dose at 2 p.m., increased dryness there, followed by secretion of mucus, as in catarrh. Dry uncomfortable feeling in rectum, which feels as if it were filled with smal! sticks. 6th — One dose. Dryness of throat for 6 h., painful. General prostration. 7th. — At 10, 4, and 9 same dose. In latter part of d, ineffectual desire for stool, with strainings dryness and heat in rectum, with feeling as if folds of mucous membrane obstructed passage, and as if, should efforts continue, rectum would protrude. For 3 d. after soreness there, with increased secretion of mucus and continued ineffectual desire for stool, loth* — Two doses without effect, save nausea, i ith. — Early in m. feeling of emptiness and gnawing in stomach. Dose at 10 a.m. After eating stomach feels full, and considerable pain exists there for 4 — 5 h., with quite severe pain in r. side of head above temple. At 3 p.m., another dose. Soreness at tip of tongue j even thinking of drug produces nausea ; rectal symptoms the same, (Hale, Nrw Rejnedies^ 2nd ed.)
- Dr. Burt, a, March 14th, 1864, 10 a.m., took gr. 10 of i^ trit. From it to 4, flying " neuralgic " or constrictive pains in various parts, chiefly about praecordia ; and dull aching in small of back, increasing in severity, aggravated by motion. At 4, took gr. 20, Same pains, also aching in knees, and from pit of stomach to r. lobe of liver. At ID, with same pains, and feeling as if something had lodged in fauces, producing constant inclination to swallow, took 20 grains more« 15th. — Called up more than once in n., back always aching, as it is in m. At 7 a.m., took gr. 20, At noon, dull frontal headache j fauces feel dry and constricted, burning distress in stomach, frequent eructation, very tired and languid, back aches severely. During d, frequent pains in umbih'cal and hypogastric regions. For 2 d. no stool. 16th. — Very hard and dry stool at 7 a.m., followed by colicky
• Nausea and salivation recurred after almost every dose, and will therefore not be rcpcatcd,^ — Eds*
pain in umbilicus and severe cuttings in anus. At 9, took gr, 10. Internal burning, backache, flying neuralgic pains, and sensations In fauces, occurred as before. At noon, pulse being 68, soft and weak, took gr. 40. Same results ; with frontal headache, great constriction of skin of forehead ; with throat sensations, dry hacking cough } with burning, fluttering sensation at pit of stomach, lasting 5 m., and recurring five times ; frequent dull aching in r. hypochondrium, and faintness at epieascrium. In e., frequent twitchine of muscles under ]. eye. 17th. — Very dry and hard knotty stool, voided with great difficulty ; same on 19th with prolapsed feeling at anus after it. Symptoms had now subsided.
b. On 22nd, feeling well, took 20 grs. of pulverised nut at 10.30 a.m. In \ h. smarting of tongue and eyes, constriction of fauces; dull umbilical aching. At 1 1.45, severe neuralgic pain in heart, lasting 10 m., and arresting breathing ; r. hypochondrium and back beginning to ache. By noon all previous symptoms had recurred, and they lasted all day. In e. ^uces looked dark and congested, and an evacuation took place with difficulty as before. 23rd. — On waking, still feeling as if portion of anus was prolapsed, with dull backache. At 9 a.m., took 30 grs. Same pains, with profuse secretion in nostrils, and feeling of much depression. At 4.30 p.m., another 70 ers. All pains worse ; throat again shows much congestion ; same kind of stool in e. 24th. — In m. tongue very much coated yellow, and sweet, flat, slimy taste in mouth. Burning distress in stomach continues ; also backache on first rising, but it becomes easier on moving about* At noon, took 30 grs., with usual eflfects. At 2, great desire for stool : when passed, first part was black and hard, second of natural consistence, but white as milk ; severe tearing pains in anus followed. At 4, took 40 grs. This e. congestion of fauces was accompanied with constant aching distress in them \ legs also ached much, and he felt so weak that he had to lie down aU the time. 25th. — Slept soundly ; but pains in stomach, liver and back were all present on waking, with a severe frontal headache, which lasted all forenoon. Moving produced violent pains in sacrum and hips ; urine was very high-coloured. Was obliged to lie down all forenoon, feeling feverish ; hands hot and dry but pulse 66 only, soft and weak. At 3, feeling very weary and low-* spirited, took 30 grs. Nothing fresh occurred. 26th. — Slept soundly » backache went oSi on movement, and he felt well. At 10 a.m., took 60 grs. Pains in throat, heart, epigastrium, r. hypochondrium and lum bo-sacral region recurred in much force : with epigastric pain was weak, ^int feeling. At 9 p.m., stool of natural consistence^ but very white. 27th. — Symptoms moderating ; dry, difficult stool in e. 28th. — The same, with frequent griping and desire for stool, which two soft evacuations do not relieve. 29th. — The same : stool black as well as soft. April 1st. — Still a good deal of pain in lumbar region, with soft mushy stool. {Ibid,)
- Dr. T. C. Duncan, act. 24. Well, save some weakness of bowels. JVhy 6th, 1865, took gtt. xij of 2* dil. During d. heat and soreness in epigastrium ; memory and power of attention weak ; slight pains here and there. In e. continued pain in back, shoulders and
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necVj at times with pricking sensations ; profuse coryza, with feeling in nose and forehead as if he had taken cold ; fulness and itching at anus after walking a mile 7th. — Slept well, but woke with still some symptoms of catarrh, dull heavy pain in back of neck ; itching ID anus, with some heat. At 8 am.^ took gtt. xv. Neck and anus sensations continued; ideas confused; no stool, 8th. — At 7 a.m., took gtt. XX of ly diL Nausea ; mouth and pharynx feel irritated ; pressure, burning, itching and fulness at anus ; flushes of heat over body ; soreness of neck, with pricking sensations ; head, chest and upper abdomen feel congested, later surface in general. Stool very costive; urine frequent and hot. 9th. — In n. distressful and exciting dreams ; on awaking feels sore all over, feet swollen (became so on 8th after an ordinary walk), cervical glands slightly enlarged and tender to touch, limbs heavy and joints stiff. Throat, anus, stool and urine as yesterday. Mind still confused and temper very irritable At 8,30 a.m., took gtt. xxx of Xj, By 9 mouth and throat were dry ; sharp, darting pains affected trachea, producing tickling cough ; there was heat in stomach and thorax, and all over body ; ineffectual attempts at stool, and soreness at anus. Yawning and stretching were followed by chilly sensations, especially when riding in cool air; anterior head feels light, posterior heavy and dull; great pain in sacro-lumbar region; whole body heavy, weak, sore, and painful on motion ; r. hypochondrium tender, later full ; lids twitch, balls are sore, and n eye pains when near light; head tight and full, as in catarrh ; itching of whole body, especially round waist. In e., after great fulness and pressure, and with much straining and shivering, expulsion of about 8 10. of fa?ces, like a rope, solid, knotty, first half dark, second light in colour; great soreness of anus, sphincter seemed unable to contract ; about J in. protrusion, which he had to push up; great burning and itching. Had been very drowsy all day, and now soon went to sleep.
He now took no more medicine, but symptoms lasted 3 d. longer. Pains, soreness, heat and fulness, and languor, were present on loth, with dull supra-orbital aching; want of control over tongue, which feels swollen ; tenderness of abdomen ; no stool. Felt dull, gloomy and despondent. Skin dry and hot, but sensitive to cold. On nth, symptoms lessening ; hard stool, with usual effects at anus ; mind clearing. On 1 2th, a small stool, thin, watery, light-coloured, with some tenesmus. Easier altogether, but weak and d,isinclined to study, {Ihid,)
1 1. Dr. C. H* Lee began on Dec. 26th, 1863, by taking one drop of 3rd dil. Symptoms (acute febrile tonsillitis) which followed were quite foreign to the drug, and pretty certainly the results of cold. On Jan. 2nd, these having left him, took 4 drops of tincture. On 3rd and 4th, appeared hemorrhoids like ground nuts, of purple colour, very painful, and with sensation of burning (prover never had piles before). On 6th, felt dryness in soft palate, fulness in head ; urine dark, with some little sediment. Took 8 drops. On 8th, throat dry and swollen. Took 5j, On 10th, throat same ; severe headache as if head would split; desire to pass water often, but little at lime. On nth, with these symptoms, burning in throat and palate; much thick yellow phlegm in mouth j tongue coated yellow ; bowels loose, stools brown i
urine scanty and dark brown^ no sediment ; pulse hard and frequent ; dull aching in I. elbow. He took no more of drug j symptoms began to diminish on 12th, and had gone by 14th* (/^/^)
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Dr. H. M. Paine took from 10 to 30 drops of tincture daily from Sept. a8th to 3Cth, On Oct, ist, general headache, with fulness in upper prt. Very annoying vertigo all afternoon. General malaise. Same symptoms next day till 4 p.m. At 9, took 40 drops. A ficw m. after quick, severe griping pain in epigastrium for { h. On 3rd, felt miserably cross and disinclined for any labour. Headache and vertigo as before until e. At 10 p.m., took 40 drops, and same pain followed. On 4th, but slight disorder: took 40 drops more in e. On 6th, for first time since beginning proving had rather difficult stool. Forty dropis in e. On 7th, another such stool, followed for i h. by slight soreness, aching and fulness in rectum. Took 50 drops in €,> but no further symptoms were experienced. (Ibid,)
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Dr. Woodward Warren, a?t. 36, nervo-biHous temp., subject to gastric and bilious derangements. On May 22nd, 4 p.m., took
2 grs. of ij trit. Slight uneasiness in fauces, stomach and bowels ensued, with dull pains here and there in head. On igth^ same dose of 2„ and same symptoms, but also ineffectual urging to stool, and constriction of rectum. 30th. — At 6 a.m., difficult scanty stool. At 8, took 3 grs. In 10 m. coppery taste, with increased saliva. Some headache and nausea after ^ h., and at 9 lameness and weariness in nucha and small of back. 31st. — Took 2 grs. At 9 a.m. copious soft stool, followed by burning and feeling of swelling and constriction in rectum. Slight symptoms as before in head and abdomen, also confusion in head and giddiness, with flushes of heat on surface from occiput to shoulders, and burning in ears. June 7th. — Took 5 grs. at noon. Same symptoms as on 31st ; also burning and stinging deep in 1. orbit, as if pain surrounded ball of eye, with feeling of coldness in eye j and (2.30) general feeling of malaise, with stupefying feeling in head^, and lameness in the back. 8th, at 7 a.m., difficult hard stool, followed by burning and sense of constriction in rectum* At 9, took
3 grs. Same symptoms as heretofore. {Ibid,)
Volume II — Appendix
Esculus Hippocastanum.-After I. 13, insert the following : 14. a. Dr. NEIDHARD took 3 gr. Immediately after, slight nausea with pressure in the stomach; for 1 h. tickling cough from larynx with expectoration of white phlegm ; is not so soon sleepy in e, as is habitual to him; unusual pain in e. onmicturition; all n. dreams and frequent awaking; constant discharge of flatulence ; a verycopious evacuation from bowels at n. and also one in m.; pain in sacral region ; wakes np unusually early inm. b. Same took 10 dr. of tinct. at 8 a.m. For h. dull pain in r. side of forehead, extending gradually also to other side; almost simultaneously sensation of warmth and sick stomach, lasting h.; for h. sensation of inward strength extending to sacrum. About 12 commenced oppression in region of heart with palpitation. Next d. appearance of red blotches with itching on 1. knee and different parts of body. The third d. a kind of rheumatic pain in l. knee, just as he had once many years before. The pains pass off in afternoon. Took 30dr. at 3 a.m.; very fine tickling in larynx ; hawking of tough viscid phlegm. The whole n. erections,with. out voluptuous dreams or seminal emissions. (Communicated.)