Apocynum androsaemifolium

Volume I — Main text

APOCYNUM ANDROSiEMIFOLIUM.

Apocynum artdfommifolium, L* Spreading dogbane. Nat. Ord., Apwynaee^,

I. P rowings, — I. Dr. J* H« Henry and two ladies proved a strong tincture ot fresh root simultaneously. All were in good health. " We first took 50 drr,, fast* ing, in m. J two of us had cramps in soles, third violent heat there with profuse general sweat. On 15th each took 100 drs, ; all felt cramps and burning in soles«1 most \n my r. foot^ with great pain in joint of 1. big toe and heat in r. leg and knee. One lady with myself complained of great fiilncss with indescribable pain in head. Next m, bowels of all costive. On 16th 150 drs ; same symptoms as on 15th, tingling pains in my toes, trembling of body of two provers, most delightful taste In

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mouth of each, everything smells like honey to me, ail complain of pains In different parts of the body, much pain in my r, knee and shoulder. The ladies complain of pain in all teeth of L lower jaw. On 17th 200 dr*, i I aJone felt cramps m soles | all other iymptom* felt as on i6th; pain and stiffness in back of head and neck; dull boring pain when breathing, seems to go from above downwards. On tSth 150 dns. Bilious painful diarrhoea in myself and one of the ladies. On 19th ^oo drs. Heaviness of body with great desire to sleep ; flying pains all over j pain in head and back of neck * swollen sensation with violent itching of face and body. On 10th each took 350 drops. All above symptoms felt; profuse flow of clear urine; pulsating pain in back of head and between r. hand and elbow ; constipation in two ; diarrhoea in the third with much pain and rumbling, only two evacuations, but large, giving much relief. On 21st eacn took 400 drops. Much pain all over head j stilFneu of neck ; pain on turning to 1. side ; itching and burning of face ; most violent pain in all joints; great itching in 1. nostriL On a3rd 500 drs. Violent pain in I. jwgoma ; chilliness, lassitude ; beat of head and neck ; cannot sleep at n. ; vivid dreams; sleep not refreshing ; shooting pain in 1. groin. On a4th 550 drs. Profuse menses, lasting Z d., with violent pressing pain; other symptoms a* before. On isth 600 drs. Some flying pains in stomach ; fulness and pain in r. side ; increase of all other symptoms, with great pain in all 1. side of head and above each wrist. On a 6th 650 drs. Some efforts to vomit ; pain increased in back of neck, extending to front; wor^ also above wrists; one prover had four bilious evacuations, another two, the third was constipated. On ijth 1800 drops. All sick, with vomiting, purging, great prostration and trembling of body. {FAilaJ. Journ, o/Hom.f lii, 3 6^0