MERCURIUS CORROSIVUS.

Mercuric chloride, Hgcl.

Hydrargyrum bichloratum corrosivum; Mercurius sublimatus corrosivus; Bichloride of Mercury; Corrosive sublimate (oxymuriate of mercury).

Preparation for use , Triturations or solutions.

Authorities.

1 , Hahnemann, R. A. M. L., 1, 422; 2 , C. Fr. Schwarze, Beob. et Erfahr. Dresden, 1827 (from Hahnemann); ( Nos.

3 to 10, provings from Dr. Buchner's Monograph supplement to All. Zeit. f. Hom ., Augsburg, 1849); 3 , Buchner, took one dose of 2d dil.; 3 a , same, three months later, same dilution, one dose; 3 b , same, rubbed into forearm, a solution of 1/2 a grain in Alcohol; 3 c , same, rubbed solution of 1/2 a grain into the gums; 3 d , same, took a clyster of 1/2 a grain in solution; 4 , Dr. Forstner, took of a solution of 1/50 grain in 110 drops of Alcohol, 2 drops first day, 4 drops second day, 7 drops third day, 10 drops fourth day, 15 drops fifth day, 20 drops sixth day, morning and evening, 20 drops eight day, 5 drops tenth day; 5 , Dr. Gerster, took daily doses of 2d dil., for seven days, increasing from 5 to 40 drops at a dose; 5 a , same, took of a solution of 1/4 grain in 1 drachm of Alcohol, 10 drops first day, 15 drops third day, 20 drops fourth day, 14 drops eight day; 6 , Kathrina, aged twenty-one, took of same solution, 10 drops first day, 15 drops second day, 20 drops fourth day, 25 drops sixth day; 7 , Dr. Held, took 2d cent. dil., 2 drops first, second, third, sixth, seventh, tenth, eleventh, and twelfth days; 8 , Dr. Nusser, took 2d cent. dil., 10 drops first day, 3d dil. by olfaction ninth day; 9 , Maria, aged forty-six, effects of a large number of pills, each containing about 1/20 grain; 10 , Dr. Pemerl, took 2d. dil., 5 drops first day, 12 drops second day, 18 drops third day, 25 drops fourth day, 30 drops fifth day, 36 drops eighth day, 30 drops tenth day; , Cloquet, from Buchner, effects of repeated immersion of hands in a concentrated solution, while preparing anatomical specimens; , Baccius, Prolog. ad lib. de Venen. et Antidotis, Rome, 1506, p. 21 (from Buchner), effects in an infant; , Magneti, Bibl. Med.-Pract., 1739 (from Buchner), a child, a year and a half old, took 8 grains; , Houlston, poisoning of a woman by a solution, Med. and Phil. Comm., 1779, vol. 6, p. 327; , Dumonceau et Planchon, effects of a large quantity in a man, Journ. de Méd., 1778 (Frank's Mag., 1, 774); , Plenck, Toxicol., 1785, p. 263 (from Buchner), effects of clyster containing Merc. corr., in a old woman; , Degner, Act. Nat. Cur., vol. vi, appendix, 1742 (from Buchner), effects of ointment containing Merc. corr., to an induration on leg, in a woman, aged forty-seven; , Wedel, Diss. de Merc. dul., p. 22 (from Buchner), effects of 10 grains, in a child, aged two years; , Dr. Henry, Edin. Med. and Surg. Journ. 1811, p. 150, took nearly 1 ounce, in hot water; , Robertson, Edin. M. and S. Journ, 1812, vol. 8, p. 195, effects of using a solution of 4 grains to an ounce, on an eruption, which began to disappear the fifth day; , a girl took 1 drachm in beer, Fothergill's Journ., 1819 (from Buchner); , Anderson, effects of application of a solution of 30 grains to an ounce, for rheumatism in arm, Edin. M. and S. J., 1811; , Thomas, a woman (a month after parturition) drank a solution of 30 grains to an ounce, that had been prescribed for an eruption, Edin. M. and S. J., vol. 16, p. 510, 1820; , Ward, effects of rubbing whole body with an ointment, containing 1 ounce of M. corr., in a man, suffering from the itch, Lond. Med. Gaz., 1829; , same, effects of same, in a brother; , Westrumb, a man took nearly 3 drachms dissolved in water, Rust's Mag., 1834 (Frank's Mag., 1, 573); , Lowenhardt, a man took nearly an ounce, Med. Zeit. f. Heilk., Preussen, 1839, No. 7 (from Buchner); , Alex. Wood, a man took half a teaspoonful in some whisky, Edin, M. and S. J., 51, 114, 1839; , Blacklock, a man took upwards of a drachm dissolved in water, Edin, M. and S. J. 36, p. 92, 1831; , omitted; , Stringham, effects of 6 grains in four dose, in a man, with gonorrhœa, Med. and Phys. J., 10, 283; , Budd, effects of 1 ounce in a woman, Med. and Phys. J., 18, 347; , Evans, effects of 1/2 a drachm in a man, Med. and Phys. J., 3, 535; , Kimball, effects of about 3 grs., applied to herpes of scalp, in a girl, aged twelve years, Bost. M. and S. J., 4, 220; , Meeker, effects of plaster containing about 100 grains, applied to a scirrhous tumor of mamma, Bost. M. and S. J., 39, 18; , Masselot, effects of two doses, each of 3/16 grain, Hempel's Mat. Med.; , same, repeated; , Devergie, effects of an indefinite quantity in a woman, from Hempel; , Orfila, effects of a large quantity on a man, Toxicologie; , Trousseau and Pidoux, effects of baths of Corros, subl.; , omitted; , Provin. Med. J., 1843 (from Buchner), effects of parts of a powder containing 1/2 a drachm, in a woman; , Buchner, effects of pills containing Corros. subl., taken for neuralgia, in a man, A. H. Z., 28, 155; , Frisselle, a woman, aged twenty-six, took 1 drachm in a solution, Bost. M. and S. J., 41, 279, 1849; , Guy's Hosp. Rep., N. S., 5, a man took about 1 drachm; , same, a young woman swallowed a little of a solution (indefinite); , same, similar to last dose, fatal; , Vautier, Gaz. Méd. de Paris, 1842 (S. J., 39, 22), effects of about 2 grains; , Andrew, effects of about 40 grains, in whisky, L. and Ed. Med. J., Feb. 1845; , Watson effects of about a drachm, in a man, L. and E. M. J., May, 1844; , Percy, effects of 30 grains, in a girl, aged seventeen, Lond. Med. Gaz., March, 1843; , Gaz. des Hôp., 1844, effects of application of a solution of thighs and scrotum; , Laduit de la Charriere, effects of 10 grammes, in a woman, aged twenty-one from Tardieu sur l'Empoison, p. 695; , Ollivier, effects of about 1.1 gramme, in a woman, aged sixty-two, from Tardieu; , Vigla, effects of 3 or 4 gramme, in a man, Gaz. des Hôp., 1859; , Prael, effects of an indefinite quantity in an epileptic, Ammons monats., S. J., 31, 33; , Deutsch, effects of application of a solution of 6 grains to 6 ounces of water, to an eruption, in a boy, Preus. Ver. Zeit., 1851 (S. J., 72, 31); , same, effects of a both of Corros. subl., for an eruption, in a girl, aged fourteen, S. J. 90, 295; , omitted; , Butcher, effects of a vaginal injection of more than, 1/3 of a solution of a drachm of Corros, subl., in lime-water, in a woman, aged twenty-five, Dublin Quar. J. of Med. Sci., 1856, vol. 21, p. 242; , Thomson, effects of 2 drachms, in a man, Lond. and Ed. Med. J., 13, 582; , McCready, effects of about 22 grains, in a young woman, N. Y. J. of Med., 1850; , Williams, effects of about 30 grains, in a man, Am. J. of Med. Sc., 1851, vol. 21, p. 79; , Coale, effects of part of 10 grains, in a man, Am. J. Med. Sc., Jan. 1851; , Roberts, effects of 1/2 a drachm in 1/2 an ounce of mur. tinct. of iron. Med. Times and Gaz., 1859, p. 210; , Auer, effects of half a spoonful of a solution of 10 grains in an ounce of water, taken for pain in stomach, Bavar. Intell., 131 (S. J., 109, 291); , Haight, took a spoonful of a strong solution, U. S. J. of Hom., 1, p. 7; , Robinson, proving in a young woman, of 200th dil. in water, a teaspoonful every third morning, Br. J. of Hom., 25, 324; , same, in another case; , Ord, effects in a man, from tasting it, Am. J. of Med. Sc. Jl., 1861; , Cabot, fatal effects in a woman, aged twenty-five, Bost. M. and S. J., 65, 218; , De Ricci, effects on two boys, of application of ointment containing 2 drachms, for porrigo, Bost. M. and S. J., 51, 249, from Dubl. Q. Journ.; , Skegg, effects of a 1/4 of an ounce, in a man, Lancet, Feb. 1862; , Garnsey, effects of a small dose of 1st dec. trit., for sore throat, Am. Hom. Obs., 1868, p. 470; , Anderseck and Hamberger; effects of an ointment of Corros. subl., in two girls, for an eruption, Vjs. f. ger. Med. (Syd. Soc. Yr. Book, 1864, p. 431); , Coghlan, effects of 12 grains in whisky, in a stout healthy lad, for gonorrhœa, Med. Times and Gaz., 1860, p. 162; , Taylor, effects of 2 drachms, in a man, Guy's Hosp. Rep., 1844, p. 24; , Lucas, effects of a quantity in vinegar, on a man, Med. Times and Gaz., Sept. 1871; , Eade, effects of a "small lump," which remained an hour in the stomach, and was then ejected by vomiting, Lancet, Feb. 1870; , Brewer, effects of a strong solution, in a woman, aged twenty, Med. Invest., 7, 160; , Berridge, effect of 1600th dil. (Fincke), two doses, Am. J. H. M. M., 8, p. 126; , Anderson, effects of 1 drachm, in a girl, aged twenty-eight, Ed. M. and S. J., 14, p. 474; , Ogston, effects of 2 drachms, in a man; , Taylor, effects of 5 to 10 grains, in vinegar, Guy's Hosp. Rep., 1864; , Hort effects of a solution (indefinite), in man, from Tardieu; , Lorenzo Rota, effects of an indefinite amount in a man, Italian Med. Gaz., 1851 (S. J., 74, p. 167); to , Valentine, a woman administered to self and children large doses; , girl, aged three; , boy, aged eleven; , the mother; , boy, aged eight; , girl, aged fourteen, Edin. M. and S. J., 1818, vol, 14, p. 468.

MIND

• Emotional.
• Brain evidently much affected, 84.
• Delirium, 17, 30 ; (fifth night), 79.
• Delirium; was obliged to be forcibly confined to his bed (fourth day), 72.
• Completely delirious (after forty minutes), 67.
• Rather low-spirited, 76.*
• Greatly depressed (sixth day), 79.*
• Her groaning alarmed the family (after half an hour), 75.
• Anxiety, 43 ; (after second day), 19.
• Increased anxiety, during the night, 35. [10.]
• Great anxiety; she dared not stir, as the pain and vomiting were renewed by the least pressure on the stomach (after two hours and a half), 49.
• Ill-humor, in the afternoon (thirteenth day), 7.
• Frequent ill-humor, so that nothing will please him; alternating with joyfulness, 1.
• Very ill-humored all day (third day), 7.*
• Intellectual.
• Dulness of intellect, though rational when fairly awake (fifth day), 63.
• When he spoke his thoughts were disconnected, indeed, he could not clearly describe his sensations; he spoke of three kinds of headache, remarked upon their disassociation, tried to correct himself, until he was obliged to stop from weariness (second day), 3.
• Stupid, pale, with dry unsteady eyes, 81.
• Weakness of the intellect; he looks at us with wide-open eyes, and does not understand us (after two hours), 1.*
• Mind so weak in the evening, that I looked sometimes at the person talking to me without really understanding him (twelfth day), 7.
• Required to be aroused to give answers to questions, 61. [20.]
• Intellect slightly affected; a little stupor (third day), 51.
• Lay in half stupor (sixth day), 79.

HEAD

• Confusion and Vertigo.
• Confusion of the head, relieved by emission of flatus, 9.
• Confusion, heat, and heaviness of the head (sixth day), 25.
• Head somewhat confused (eighth day), 7.
• Several attacks of vertigo, 35a. [30.]
• Slight vertigo (fourth day), 5.
• Excessive vertigo (third day), 77.
• A kind of whirling vertigo, with good vision; almost entire loss of hearing, lasting from half an hour to an hour, especially at 9 P.M., on lying down, seldom during the day, with tearing pains in the occiput, 9.
• Dizzy whenever he lifted his head from the pillow (after two hours and a half), 39.
• Giddiness (after six hours and a half), 41.
• General Head.
• Dulness of the head (fifth day), 5 ; (sixth day), 7.
• Dulness in the head, especially above the eyebrows (third day), 10.
• Heaviness of the head (after one bath), 38.
• Head heavy and confused (second day), 3.
• Heaviness and dulness of the head (fourth day), 5. [40.]
• Great uneasiness in head, 30.
• Much pain in the head (third day), 61.
• Violent pain in head (second day), 72.
• Congestion to the head and face, with burning in the cheeks (eleventh day), 5.*
• Headache (after six hours and a half), 41.
• Frequent headache, especially in the temples, 17.
• Severe headache (after half an hour), 59 ; (fourth day), 24.
• Intense headache (seventh day), 20.
• Headache dull, dizzy, 9.
• A severe, sudden dull aching pain in forehead and vertex, worse on stooping or shaking head; relieved by applying the cold hand to the forehead (almost directly after second dose); it extended to centre of cerebellum, when it felt like a , about 5 P.M. (after five hours and a quarter); during tea-times (6.15 P.M.) it went off; it made him feel rather low-spirited, . [50.]

EYE

• Objective.
• Staring look, 2.
• Eyes red, glistening, 25.
• Eyes bloodshot and protruding from sockets (after half an hour), 65.
• Eyes sparkling, 15.
• Eyes glistening and injected (sixth day), 25. [70.]
• Eyes glistening, and in constant motion, 37.
• Eyes dull and dim, and expressive of agony (after five hours), 36.
• Inflammation of the eyes, which protrude from their orbits, 2.
• Subjective.
• Eyes painful (eleventh day), with some injection of the vessels of the conjunctiva; the pain was pressive burning (twelfth day), 7.
• Burning in the eyes (eighth day), 5a.
• Burning in the eyes, and on the margins of the lids, as in commencing conjunctivitis (after four hours, first day), 5a.
• Burning and a sensation of dryness in the eyes (fifth day), 5.
• A contraction of the corrugator supercilii, with partial strabismus (third day), 86.
• Tearing as if the bone above the left eye, near the root of the nose, and in other parts of the bone (first day), 8.*
• Burning tearing in the upper part of the left upper eyelid (first day), 8. [80.]
• Itching of the left eye (first day), 8.
• Conjunctiva.
• Redness of the conjunctivæ, 37, 64a.*
• Conjunctiva of both lids red and much injected (fifth day), 5.
• Conjunctiva injected (after half an hour); less so (after three hours and a half), 59.
• Ball.
• Pain behind the eyeballs as if they would be forced out, 64a.
• Itching sticking in the muscles of the right eyeball (eleventh day), 10.

EAR

• Ear seemed stopped, 9.
• Sticking within the left ear (fifth day), 8.
• Pulsation in the left ear, as if caused by an artery (seventh day), 7.
• Violent pulsation in the ears, especially in the left (eleventh day), 7.*
• Hearing.
• (Frequent roaring and humming in the right ear, which he usually has, very much increased), (fifth day), 5.
• A whirring in the left ear rhythmical with the pulse, 1.

NOSE. [100.]

• *Excessive coryza, 1.
• Frequent nosebleed (eighth day), 25.*
• Constant sensation of dryness posteriorly in the nose, as if in the upper surface of the soft palate, especially in the open air (fourth and fifth days), 8.

FACE

• Objective.
• Expression of mental exaltation and bodily pain, 25.
• Face expressive of anxiety, 21.
• Countenance denoted exhaustion (ninth day), 27.*
• Countenance exhausted and sunken (eight day), 20.
• Lying with his eyes half shut, and with quite a choleraic aspect (after one hour and a half), 61.
• His aspect is precisely that of a patient attacked by cholera, but who has not yet reached the stage of perfect collapse (after one hour and a half), 59.
• Face red (sixth day), 25. [110.]
• Face red, puffy, soon, 37.*
• Countenance flushed (after one hour and a half), 41 ; (third day), 42 ; (seventh day), 20.*
• Countenance flushed (after one day); and fuller than usual (second day), 28.*
• Face rather flushed (after eight hours and a half), 74.*
• Lividity of countenance, 43.
• Face pale (after four hours), 50.
• Face pale (tenth day); extreme pallor (fifteenth day), 51.
• Paleness of the face in the night, 35.
• Face pale, colorless (after five hours), 36.
• Countenance pale and anxious (after one hour and a half), 45 ; (second day), 79.* [120.]
• Countenance pale and anxious and features pinched (after one hour and a half), 73.*
• Face pale and sunken, 53.
• Face pale, sunken, with an expression of anxiety, 44.
• Pale face, with sunken eyes, as in cholera (after two hours and half); yellow, hippocratic countenance (fourth day); face greenish (fifth day), 49.
• Blanched (sixth day), 79.

MOUTH

• Teeth.
• Much sordes about teeth (eleventh day), 61.* [160.]
• *Teeth loose, 17 ; (third day), 22.
• Teeth very loose, 21.
• Teeth begin to feel loose (fifth day), 61.
• The first time she attempted to take animal food the teeth appeared to refuse their office; they seemed loose and blunt (after a week or more); about this time also bits of dead skin came away from the throat and mouth, resembling the peelings of roasted potatoes; a tooth had been drawn some little time before, and from the vacuity it had left a large piece of the gum came away; from the side of the tongue a portion also separated, of the size of a large pea, leaving a cavity corresponding to its extent; the tongue, gum, and throat continued tender while these substances were coming away, 23.
• Toothache gradually becoming worse, connected with a tearing extending from the infraorbital region down towards the upper jaw (third day), 7 . [This pain had a decided similarity to the painful sensation caused by Urtica urens touching the mucous membrane.]
• Sleep at night disturbed by toothache and by an anxious sensation (third day), 7.*
• Toothache; it prevented sleep and was associated with disagreeable swelling of the gum, and prostration (seventh day), 7.
• Toothache, with swelling of the gum (thirteenth day), 7.*
• Drawing pains in the teeth, 3c.
• Tearing sticking in a back tooth, from which the sticking extends to the ear (first day), 8.
• Gums. [170.]
• Gums purple (fifth day); spongy, ulcerated in several places (sixth day), 61.*
• Gums red and detached from teeth (third day), 22.*
• Gums red and tender, with some swelling of the glans beneath the jaw (third day), 56.*
• Marked redness of the gums, walls of the mouth, and pharynx, showing intense inflammation. These parts exhaled a nauseating odor (third day), .

THROAT

• *Great swelling of the throat that threatened suffocation; the swelling extended to the neck head, and tongue; the throat was so much inflamed that the patient could speak with difficulty and could scarcely swallow; on the third day there was still great heat in the mouth and throat, as from a glowing coal; on the fourth day the patient raised some clots of blood and some thin blood, so that the physician thought she might die of hæmorrhage; the patient was unable to talk on account of the ulceration of the throat and soft palate, with copious salivation, with frequent headache, especially in the temples; on the succeeding days the patient became delirious, was unable to swallow medicine or food; she expectorated daily clots of blood and pieces of membrane from the ulceration of the throat, with excessive prostration and constant salivation; the sloughing extended to the cheeks, gum, palate, and even the maxillary bone were laid bare; the lips became black, the patient sank and died, 17.
• Great uneasiness in throat, 30. [290.]
• Pain in the throat, at times in the uvula, not aggravated by swallowing (third to fifth day), 8.
• Pain in the throat, especially after dry bread, 9.
• A little pain in the throat (after half an hour), 59.
• Severe pain in throat (after two hours), 77.
• Throat very painful and inflamed, 21.*
• Burning in the throat and stomach (third day), 42.*
• Burning sensation in throat (after four hours), 50.*
• Burning sensation in the throat (immediately), 79.*
• Burning heat in throat and stomach, particularly the former (soon), 45.
• *Burning pain in throat (after one hour and a half), 41. [300.]
• Burning pain with a feeling of constriction from the throat to the stomach, 81.
• Burning pain extending from the mouth to the stomach, relieved by a drink of cold water (thirteenth day), 7.
• Acute burning sensation in the throat while swallowing it, 27.
• Painful burning, extending from the mouth to the epigastric region, .*

Great difficult of swallowing (sixth day), 74.

• Deglutition so difficult and painful that the least attempt to swallow a drop of liquid caused spasms of the œsophagus and stomach, with vomiting of whitish, slimy, tenacious masses which became mixed with bile if the vomiting continued any length of time (after five hours), 36.*
• Could not swallow, as her throat was drawn together, and sometimes entirely stopped (after ten minutes), 77.
• Impossible to swallow; the attempt only caused retching and vomiting, 26.
• Dysphagia, 83.
• Complete dysphagia, 85.
• External Throat.
• Much swelling of the throat, 16.
• Throat enormously swollen, 52.
• The external fauces, particularly on the right side, and also the right side of neck, much tumefied (soon), 46.
• All glands of jaw, etc., swelled (third day), 33.* [370.]
• Submaxillary region much swelled (after four hours), 57.
• Submaxillary glands enlarged, 43a.*
• Submaxillary glands enlarged and tender (fifth day), 34.*
• Submaxillary glands swelled considerably (after forty-eight hours), 48.
• Salivary glands very much swollen, 52.*

STOMACH

• Appetite.
• Strong propensity to eat Cayenne pepper since her illness, 31.
• A little less appetite than usual (second day), 35.
• Appetite wanting (twelfth day), 7.
• No appetite for some hours after a dose, 9.
• Loss of appetite, in the evening (tenth day), 7.
• Thirst. [380.]
• Thirsty (second day), 74.
• Some thirst, in the evening (tenth day), 7.
• Thirst and desire for ice (after two days), 63.
• Considerable thirst, 11, 65.
• Considerable thirst, so that she stopped to drink water almost at every ditch (soon), 14.
• Much thirst (second day), 45.
• Great thirst (first night), 70 ; (second day), 31.
• Great thirst, with bad appetite (thirteenth day), 7.
• Thirst very great (twelfth day), 7.*
• Urgent thirst (second day), 80. [390.]
• Thirst so incessant that he asks for milk every two or three minutes, notwithstanding the distress he experiences in getting it down (second day), 28.
• Excessive thirst, 23, 40, 82.
• Extreme thirst, 84 ; (after twelve hours), 33.
• Thirst intense (soon), 46, 57 ; (after one hour and a half), 59 ; (after four hours), 50 ; (after five hours), 36 ; (for four days), 75.*
• Violent thirst, 52.
• Violent thirst; but every attempt to take liquids was followed by retching and vomiting (fifth day), 25.

ABDOMEN

• Hypochondria.
• Sticking as if in the middle of the liver (first day), 8.
• Stitches in the hepatic region (second day), 8.*
• Umbilical and Sides.
• Feeling of discomfort in the umbilical region (second day), 10.
• Passed a very bad night , complaining of great pain at the umbilicus (first night), 85.
• After the first eighteen hours, the pain removed, and became violently fixed at the umbilicus, continuing there eight hours; thence to the back (lumbar region) which continued to her death, 84.
• Colic to the right of the umbilicus, a kind of griping, after dinner (second day), 8.
• Pressing-down in front below the umbilicus immediately after a stool, lasting some time, 1. [550.]
• Colic, cutting below the umbilicus after a moderate use of sour apples, while walking in the open air, and afterwards in the evening becoming very acute, with some desire for stool (fifth day), 8.
• Itching sticking in the umbilical region (eleventh day), 10.
• Colic about and above the umbilicus, after eating bread and butter (first day), 8.
• Colic pains in the umbilical region, followed by three very thin stools with tenesmus, 11.
• Tenesmus in the umbilical region on pressure (fifth day), 79.
• A constrictive jerking pain in some muscle-fibres in the umbilical region, in the inner side of the right rectus muscle, lasting several minutes, and afterwards frequently returning (second day), 10.
• Cutting in the right side of the upper abdomen (sixth day), 8.
• General Abdomen.
• Swelling of the abdomen, 13.*
• Abdomen swollen, and generally painful to slightest touch, 53.*
• Excessive swelling of the abdomen, 53. [560.]
• Abdomen swelled as large as a woman's in seventh month of pregnancy, very hard; with pains at regular intervals, like labor-pains, 31.

RECTUM AND ANUS

• Rectum.
• Much pain in rectum (third day), 45.
• Burning heat in rectum (after three days), 28.*
• Constant burning pain in the rectum (second day), 25.*
• Violent burning in the rectum (eighth day), 25.*
• Sticking-shooting pain in the rectum (fifth day), 25.
• Stools associated with the most violent smarting pains in the rectum (second day), 25.
• Anus.
• Oozing of a corrosive ichor from the anus, that excoriated the external parts, and rendered them so sore that he could hardly bear clysters to be injected (fifth day), 32.*
• *Frequent discharge of blood per anum (fourth day), 24. [620.]
• Blood passed off freely per anum , and increased daily (third day), 33.
• Frequent burning in the anus during stool, 9.*
• Sticking in the anus (after twelve hours), 37.
• Itching in the anus (sixth day), 8.
• Urging.
• Frequent desire for stool, with increased emission of flatus (fourth day), 4.
• Tormented by constant urging to stool (soon), 36.
• Frequent ineffectual urging to stool, causing most violent pain (fifth day), 25.*
• *Tenesmus, 2.
• Persistent tenesmus, 3d.*
• Tenesmus incessant (soon), 46.* [630.]
• Very distressing tenesmus, getting worse and worse; nothing passed but mucus tinged with blood (third day), 23.

STOOL

• Diarrhœa.
• Diarrhœa, 2 ; (sixth day), (one case), 70.
• Diarrhœa and bloody stools (after forty-five minutes), 67.
• *Diarrhœa attended with tenesmus; constant desire to go to stool, the matter evacuated being scanty, chiefly blood and mucus (after eight days), 20.
• Frequent diarrhœa, with tenesmus and constant desire to go to stool, 22.
• Bloody diarrhœa (soon), 57.
• Frequent, offensive, slimy and bloody diarrhœa, 26.
• Sero-sanguineous diarrhœa (after two hours), 50.
• Purging, the dejections consisting mostly of mucus tinged with blood, 43.
• Purging of bloody mucus, with constant and distressing tenesmus, 56.* [640.]
• Considerable purging of fluid matter, containing a large quantity of blood (after three hours and a half), 73.
• Much purging, bloody stools (second day), 45.
• Great purging, partly blood (soon), 68.
• Purged violently (after three hours), 82.
• Violent purging of coagulable lymph, clots of blood, and fine pellucid membrane (after twenty-two hours), 83.
• Purged eight times in eleven hours (after a quarter of an hour), 71.
• Violent, repeated, and very offensive discharges per anum, 84.
• Repeated calls to the vase, in which were voided large pieces of a coagulable lymph, like sheets of boiled macaroni (after six hours); stools changed to a livid, fetid and grumous appearance (second day); dirty grumous, in which was enveloped a lumbricus (third day), 85.
• Bowels had acted three times; stools quite liquid and dark (after two hours and a half); bowels acted twice in the morning, very much blood in the stools; in the afterpart of the day three dark-green stools (second day); four or five times (second night); considerable purging during the day (third day); three or four bloody stools (fourth day); stools still bloody (fifth day); four or five stools with a little blood (sixth day); three or four stools (seventh day); much purging (eight day); frequent stools of a yellowish appearance (eleventh day), 61.

URINARY ORGANS

• Bladder.
• Apprehension and discomfort in the region of the bladder, as before a stool; while walking (second day), 10.
• Pain in bladder (after two hours and a half), 61.
• Urethra.
• Gonorrhœa, at first thin, afterwards thick; at last with biting pain on urinating, and stitches extending back through the urethra, 1.*
• Urine burning (tenth day), 10.* [700.]
• Burning in the orifice of the urethra (eleventh day), 7.*
• Burning in the urethra, commencing before urinating and continuing violent till the water passed; less while urinating, almost entirely disappearing after urinating, 9.
• Sticking in the forepart of the urethra, with some desire to urinate, and very fine stitches in the left testicle; in the evening while walking (sixth day), 8.
• Burning sticking in the forepart of the urethra, with a feeling of vigor and lightness after coition (sixth day), 8.
• Stitches in the forepart of the urethra while walking in the open air (sixth day), 8.
• Frequent stitches in the forepart of the urethra (after ten days), 8.
• Slight stitches in the forepart of the urethra, and at the same time in the sphincter ani; in the evening (sixth day), 8.
• Itching in the forepart of the urethra, 1.
• Violent itching in the orifice of the urethra, which was a biting while urinating, with some stitches through the whole urethra (twelfth day), 7.
• Micturition.
• Urging to urinate felt in the urethra, with scanty emission; afterwards no inclination with a full bladder, but after the evacuation of the bladder a feeling of fulness remains (after two hours), 3. [710.]
• Micturition frequent; urine passed in drops with much pain (soon), 46.*
• Upwards of one hundred ounces of urine passed in first twelve hours; no other urinary evacuation until the fourth evening, which was very scanty, and continued so until death, .

*Urine no longer limpid; rather thick, but acid as before; sp. gr. 1016.

Flakes of albumen precipitated by heat and nitric acid . Proportion of albumen, according to Mehn's formula, 24 centigr. to 50 grammes urine; i. e.

4.80 grammes per litre. Under the microscope, the urine presented *granular fatty tubuli, in large numbers, showing on their surface epithelial cells of the tubuli uriniferi, also in a state of granular fatty degeneration, 50.

SEXUAL ORGANS

• Male.
• Penis and testes swollen enormously (second day), 24.*
• (When touching the os uteri during coition a sensation of a pressive pain followed by pressure), 1.
• Violent erections, with great sexual desire (sixth day), 8.
• Violent erections during sleep, continuing after waking; during coition delayed and very slow emission (second night), 8. [740.]
• Sticking pain in the right testicle (eighth day), 8.
• Fine but acute stitches in the middle of the left testicle, continuing the next day (first day), 8.
• Sexual desire very much diminished (secondary action); scarcely ever an erection (after ten days), 8.
• Female.
• Intense inflammation of the vulva, 43b.*
• Vulva in a sloughy state (after death), 43b.
• Slight hæmorrhage from vagina (second day), 49.
• Leucorrhœa pale yellow, of a nauseous sweetish odor, 1.
• Almost immediate local pain of a most severe kind, with a sense of burning heat; urgent forcing downwards, as in labor; and profuse discharge of mucus as thin as water; on examination, the entrance and lower part of the vagina were found greatly swollen, red, hot, and discharging profusely; on the third day the discharge continued, and was tinged with blood, 56.
• Alarming increase of catamenia, 31.

RESPIRATORY ORGANS

• Larynx.
• Great irritability in the larynx (ninth day), 4.
• Voice. [750.]
• Voice hoarse, 9, 18, 53.
• Voice rough and hoarse, 25.
• Almost complete aphonia, 62.
• Cough and Expectoration.
• Paroxysms of cough during the night (third day), 49.
• Frequent attacks of spasmodic cough (fourth day), 5a.
• Several paroxysms of spasmodic cough (sixth day), 6.
• The tickling in the throat gave rise to a convulsive cough, with very severe pain-a pharyngeal cough, such as is caused by thrusting the finger into the back of the mouth. The paroxysms of cough were followed by the expectoration of bloody mucus; then, by a feeling of suffocation, with great anxiety; they recurred at short intervals (second day), 51.
• Dry cough, 1.
• Great inclination in the larynx to cough towards evening; dry cough; the larynx dry (eight day), 4.
• Hollow, dry, fatiguing cough (after two hours), 1. [760.]
• Coughed up a considerable quantity of mucus tinged with blood (after eight hours and a half), 74.*
• Spits up thick pellets of mucus mixed with blood (sixth day), 79.
• Respiration.
• Breath extremely offensive, 21.
• Breath fetid (after forty-eight hours), 48.
• Breath fetid, but the mouth is by no means sore, and there is no ptyalism (sixth day), 28.
• Breath extremely fetid (eight day), 20.
• Mercurial fetor of breath (fifth day), 34.
• Well-marked mercurial fetor from his breath (third day), 71.
• Strong mercurial fetor of breath (third day), 22, 33.
• Mercurial fetor of breath very perceptible (eighth day), 61. [770.]
• Respiration quick and catching (after half an hour), .

CHEST

• Objective.
• Rattling in the chest, 18.
• Sonorous râles in all parts of the chest, 66.
• Subjective.
• Sensation of constriction over the whole chest, 11.
• Oppression of the chest, 1. [790.]
• Shooting pains in the chest, 40.*
• Nightly sticking pain transversely through the whole chest, 1.
• Itching-sticking pain in the muscles of the right lower costal region (eleventh day), 10.
• Stitches internally in the upper part of the left chest on deep breathing (first day), 8.
• *Frequent stitches shoot through the thorax (eight day), 4.
• Frequent tearing pain in the lowest cartilages of the right ribs (first day), 8.
• Front.
• Burning pain beneath the sternum (after eight hours and a half), 74.
• A kind of tearing in the middle of the sternum, after midnight (second night), 8.
• Sides.
• Sticking in the upper part of the right side of the chest deep internally, scarcely aggravated by deep inspiration (fifth day), 5.*
• Some sticking pain in the lower portion of the right side of the chest (twelfth day), 7.* [800.]
• Frequent dull stitches in the upper part of the left side of the chest, especially on deep breathing (first day), 8.
• Fine transient stitches through both sides of the thorax, after rising in the morning (seventh day), 4.
• Burning stitches in the right side of the chest, as if in the muscles (first day), 8.
• Mammæ.
• *Painful glandular swellings about the nipple, 1.

HEART AND PULSE

• Præcordium.
• Præcordial anxiety, 15.
• Violent pain at the præcordia, 84.
• Obstruction and anxiety in the præcordia and epigastric region, followed by slight palpitations (after second dose, portion of 3/16 grain), 84.
• Heart's Action.
• The heart-beat had a tremulous, undulating motion, 48.
• "Bruit de souffle" at the base of the heart (fifteenth day), 51.
• Palpitation, 52 ; (after third dose), 35. [810.]
• More frequent palpitations, in the night, 35.
• Beats of the heart seemed remote and slow (after five hours), 36.
• Every fifteenth or twentieth beat of heart intermits (after four hours). Heart-sounds dull and intermittent (second day). Heart-beats still intermittent (owing, no doubt, to organic disease, probably mitral insufficiency), (seventh day), 50.
• Pulse.
• Small, frequent pulse (second day), 80.
• Pulse small, contracted, frequent, 25.
• Pulse small, frequent, and irregular (after one hour and a half), 43.
• Pulse rather more frequent than usual, but not full (second day), 20.
• Quick pulse (after second day), 19.
• Full and quick pulse (seventh day), 20.
• Pulse quick and feeble, 85. [820.]
• Full small, quick, tremulous, 84 ; (after eight days), 20.
• Pulse small, quick, and regular (first day); not to be counted (second day); unsteady and feeble (third day), 86.
• Quick, small, and very indistinct pulse at the wrist (first day); barely 50 (second day); 64, but small and weak (third day), 56.
• Pulse very quick and small (second day), 22.
• Pulse rapid, full, 9.
• Pulse rapid, small, spasmodic, 52.
• Pulse rapid, hard, without being particularly large, 29.

NECK AND BACK

• Tonic cramps involving the neck and back, lasting several minutes, during which respiration completely stopped, 53. [870.]
• Tension externally near the left scapula (first day), 8.
• Tearing internally in the upper part of the left scapula, as if in the bone (first day), 8.

EXTREMITIES IN GENERAL

• Objective.
• Hands and feet rather livid, shrunken, and cold (after half an hour), 59.
• Trembling of the extremities, 41 ; (second day), 32.
• Trembling of the limbs, especially in the stretched them out, 41.
• Constant trembling of the extremities, 44.
• Convulsive motions of the right upper and lower extremities, 53.
• Spasmodic convulsions of the fingers and toes, 56.
• Twitching of the limbs, 81.
• Paralytic stiffness of the extremities (second day), 25. [880.]
• Extended on her bed, without control over her limbs (after five hours), 36.
• Complete paralysis of the upper and lower extremities, a few hours before death (sixth day), 19.
• Lassitude in the limbs, and trembling when standing up and without moving (after fourth dose), 25.*
• Loss of power and stiffness of the extremities, gradually increasing day by day, with excessive pain on every attempt to change to position, until the patient became completely paralyzed, 25.
• Subjective.
• A peculiar feeling of loss of power in the deltoid muscles, and also in the muscles of the calves and thighs, without special cause (fifth day), 10.
• Feeling of weakness and shivering in the limbs (after third dose), 35.
• Numbness of the hands and feet (fifth day), (in one case), 70.
• A peculiar numbness attendant on the pains in the arms and legs; worse in the evening, better the latter part of the night and during the day, 75.
• Pain in the extremities (second day), 25.
• Pains in her limbs and arms, like those felt after long and fatiguing exercise, always worse after sleeping, 75. [890.]
• Universal pains in the limbs (after two days), 19.
• Dull pains in the extremities, with general weakness, for five or six weeks, 62.
• Drawing deep in the limbs, in the bones (seventh day), 7.
• A kind of tearing in the bones (joints of the fingers, hips, etc.), (seventh day), .

SUPERIOR EXTREMITIES

• Shoulder.
• Tearing in the left shoulder, frequently (fourth and fifth days), 8.
• Sensation as though the glands in the left axilla would become swollen; with frequently repeated transient stitches in them (tenth day), 4.
• Arm.
• Rheumatic pain (like that peculiar to windy weather) in the right deltoid muscle, while walking (tenth day), 10.
• Hand.
• Jerking constrictive pain in the right metacarpus (fifth day), 10.
• Cramps in his hands (after two hours and a half), 61.
• Sticking pain in the muscles on the back of the hand, especially in the abductor and extensor of the thumb, and in the extensors of the foot (third day), 7. [900.]
• Tearing in the left metacarpal bones (during the first days of the proving this tearing had been farther down in the joints of the fingers), (seventh day), 8.
• Fingers.
• Fine but very sharp stitches in the tip of the left thumb, in the evening while walking (sixth day), 8.
• Acute tearing in the bone of the first joints of the left index and ring fingers, and also in the first joint of the thumb, continuing next day (first day), 8.

INFERIOR EXTREMITIES

• Objective.
• Lower extremities drawn up in bed (fifth day), 34.*
• Spasms of lower extremities (after four hours), 72.
• Stiffness of the legs, 40.
• Sticking in the muscles of the lower extremities (eleventh day), 7.
• Hip.
• Pressive-sticking pain in the hip-joint and in the knee, during both rest and motion; also in other extremities, but of less intensity (twelfth day), 7.
• Rheumatic pains like needle-stitches in the lower extremities (second night), 3.
• Sticking in the left hip-joint, from within outwards (first day), 8. [910.]
• Sticking pain in the hip-joint, during rest and motion, 1.
• *Sticking pains in the hip-joints during rest, disappearing on motion (tenth day), 7.
• Shooting stitches in the hip-joint, in the afternoon (fourteenth day), 7.
• Tearing posteriorly in the right hip-joint, afterwards more to the side and externally (second day), 8.
• Thigh.
• Drawing in the thigh-bones (second day), 7.
• Knee.
• Knees drawn up (after four hours), 72.
• Leg.
• Twitching in various muscular fibres of the calves, inner side of the gastrocnemius muscle (fifth day), 10.
• The lower leg seems asleep, 1 ; (second day), 7.
• Numbness and want of feeling in the legs (after three days), 28.
• Cramps in his legs (after five hours), 61. [920.]
• Cramps in left leg (after two hours and a half), 59.
• Drawing pain in the bones of the leg (eighth day), 7.
• Tearing in the left calf extending inwards (first day), 8.
• Foot.
• Very unusual weariness of the feet and sleepiness, in the evening (first day), .

GENERAL SYMPTOMS

• Objective.
• His whole appearance much resembled that of a person in the last stage of typhus fever (after nine days), 27.
• Though supported throughout the illness with milk, gruel, and chicken-broth, he was more reduced both in bulk and strength than any patient I ever saw, in so short a space of time, 32.
• Dorsal decubitus (after four hours), 50.*
• *Lying on his back with his knees bent up (tenth day), 61. [930.]
• He rolled so incessantly from side to side that it was difficult to distinguish pulsation, even at heart (after one hour and a half), 59.
• While leaning heavily upon the left arm, on standing, a moderate trembling of the left arm and whole left half of the body (first day), 8.
• Convulsions and rigors before death, which occurred on the fifth day, 43.
• Twitchings, 16.
• Spasms, 53.
• General spasms and convulsions, 17.
• Spasms, first in the toes and feet, and then in the fingers and hands, and afterwards extending up the legs and arms (after two or three hours); a violent spasm attacked the right breast, and shot through to the back, just under the shoulder-blade; the breast became much contracted, and its milk was speedily dried up, 23.
• Violent spasms (second day), 34.
• Spasmodic motions of the muscles of the face, arms, and legs; constant cramps in all the extremities, 37.
• Whole body stiff and painful on the slightest motion (sixth day), 25. [940.]
• Great weariness and suffering in the morning, so that after shaving he was obliged to lie down again in bed and sleep for an hour (second day), 3.
• Great depression of system (soon), 72.
• *Great debility (second day), 22.
• Total debility of whole system (second day), 32.*
• Debility seemed particularly alarming (after eight days), 20.
• Weakness (ninth day), ; without having made any exertion (second day), .*

2d . The amount of inflammation and ulceration of the large intestines was such as occurs commonly with severe dysentery, and yet the dysenteric symptoms were slight, much slighter, indeed, than commonly occur in cases of poisoning by this substance.

3d . Suppression of urine continued from Monday until Saturday, the day of her death, and yet the patient retained her senses and was easily roused, exhibiting no signs of cerebral disturbance except slight drowsiness, and some tendency to wandering, 58.

• Subjective.
• Extreme sensitiveness of the whole body (fifteenth day), 51.
• Inclination to lie down (fourth day), 5.
• Great feeling of weakness (eighth day), 61.
• "Sinking feeling" (seventh day), 61. [980.]
• Some malaise (second day), 35.
• General feeling of malaise (after third dose), 35.
• Disagreeable sensation in the periosteum of all the bones, like the onset of intermittent fever, with a feeling of heat in the head towards evening (after six hours), 1.
• Pains over the whole body (fifth day), (in one case), 70.
• General pains over the whole body, accompanied by stiffness, aggravated by every motion (fourth day), 25.
• Most acute pain, as severe as the actual cautery (immediately), 34.
• Most excruciating pain all over body, more especially about abdomen, on which part and on the thighs he had rubbed the largest quantity, and he felt as if "roasting alive" (after one hour), 24.
• Sometimes easy, at other times violently racked with pain, seat of which is principally about the scrobiculus cordis and umbilicus, 83.
• Intolerable pains, 16.
• Intolerable pain, so that she ran about the room out of her senses, with loud screams, 17. [990.]
• Occasional cramps, 43.
• Fine sticking here and there in the muscles during the day, 1.
• Stitching in the parenchyma of organs, as in the lungs, liver, and very fine in the testicles (seventh day), 8.
• Drawing in the arms, and tearing in all the extremities, alternating with convulsive shudderings in the whole body; with at times loss of consciousness and oppression of the heart, 62.
• The effects continued more or less for two days, 35a.
• Every motion or change of position was painful, 25.
• Acids aggravate, 9.
• General aggravation from eating fat food, 9.
• She feels better during rest, easily becomes weak and tired after a little exertion, 9.

SKIN. [1000.]

• Skin grew more and more livid, until it became everywhere of a dusky hue, although the breathing was perfectly free, 66.
• General yellowness of skin (second day), 72.
• General paleness of the surface (fifteenth day), 51.
• Surface of body tumefied, with a mercurial erythema spreading over it (fifth day), 34.
• Eruptions, Dry.
• Eruption of many ecchymosed spots over the body and limbs, especially the lumbar region (fifteenth day), 51.
• Eruption over the whole body of pale-red, elevated, round spots, not sharply defined, disappearing on pressure, itching, looking like rubeola (after three days), 62.
• Papulous eruption (lichen), that continue to worse, so that the baths had to be stopped, 38.
• Piercing cries followed, and in twenty minutes a brown scar was found on the parts that had been powdered; around was an inflammation of a bright-red color; scar black and dry in centre, and rather humid at circumference (after thirty hours), 48.
• Round the mouth, for the space of about an inch and a half, there was a rash, such as appears often after arsenical poisoning (eldest), 67.
• Eruptions, Moist.
• All the parts which had been rubbed in a state of complete vesication (second day), 24. [1010.]
• (Painless blisters on the arms and abdomen, in the morning, disappearing during the day), 1.
• Arm greatly swollen from shoulder to wrist; in many places it was in a state of high inflammation, and in several parts covered with numerous and extensive vesications filled with lymph, much resembling the appearance that would have been produced by a large blister (second day), 22.
• Eruptions, Pustular.
• Several large pustules, of a livid hue, appeared upon the face and breast (fourth day), 32.
• A burning sensation was immediately experienced, and soon became intolerable; the next morning there was still violent burning and pricking over the whole surface of the skin, which was red and inflamed, and that evening presented at many points vesicles, such as show themselves in cases of scalding by hot fluids; these parts of the skin afterwards suppurated, 70.
• Sensations.

SLEEP AND DREAMS

• Sleepiness.
• Inclination to yawn, and frequent yawning (fourth day), 5.
• Frequent yawning and stretching (fifth day), 5 ; without sleepiness (eighth day), 5a.*
• Drowsiness (fifth day), 63.
• Rather drowsy (after three hours and a half), 73.
• Considerable inclination to sleep, 38.
• Sleepiness all the afternoon (fourth day), 5.
• One fell into a somnolent state, from which she could at first be roused by questioning, 70.
• Soporous sleep, from which she was occasionally awakened by return of the pain, 21.
• Sleeplessness.
• Sleep uneasy (sixth night), 8. [1030.]
• Sleep very light, after awaking in the night, and unable to sleep on account of confusion of the head, 9.
• Restless night (first day), 86.
• Restless night, with some mild delirium; she tried to get up (fifth day). Night restless, disturbed by constant waking; sleep for two or three minutes, followed by waking; change of position, tossing about, etc. (first night), 3.
• Night restless; sleep frequently interrupted by distressing dreams (sixth night), 4.
• Sleep restless; and for a month her dreams were of falling from high banks, and being let down into deep wells, or trying to get away from some one who was intending to murder her, 75.
• Sleep for only a few minutes at a times (second night), 3.
• Did not sleep more than five minutes at a time (first night), 79.
• Sleep for the first eight nights lasted only till three o'clock, 9.
• Sleep interrupted towards morning, 3b. [1040.]
• Woke about midnight, tossed about the bed for three hours, was unable to sleep (first night), 3b.
• *Night sleepless; could not lie comfortably upon either side (sixth night), 7.
• Inability to sleep at night, on account of anxiety (eleventh day), .

FEVER

• Chilliness.
• Surface of body rather cool (tenth day), 61.
• Skin cool (after two hours and a half), 63.
• Skin generally cold, 53.
• Cold skin, with very small, intermitting pulse, 81.*
• Skin cold and clammy (after one hour and a half), 61.
• Skin cold, and covered with sweat (second day), 80. [1060.]
• Skin cold, pale, covered with perspiration (after twenty minutes), 25.*
• Skin cold and dripping with perspiration (after five hours), 36.*
• Surface cold, and covered with a clammy sweat (after half an hour), 73.
• The whole surface of the body and limbs, with the exception of the abdomen and inside of thighs, was cold, but she complained of feeling hot, and of a burning pain in lumbar region, 66.
• Chilliness, especially in the head, in the evening (tenth day), 7.
• In the open though warm air, to which she was averse, chilliness, cutting colic, and tenesmus, 1.
• Chilliness and cutting colic, from the slightest motion, even on rising from a seat, 1.
• Frequent chilliness at night in bed, 9.
• Slight chilliness, intermingled with sudden transient heat, towards evening (first day), 7.
• Attack of chill, lasting a short time (sixth day), 6. [1070.]
• Creeping chills, in the night, 35.
• Increase of the coldness of the hands and feet, of the saliva and difficulty of swallowing, so that about 10 A.M. he was obliged to stop work, lie down in bed, and wrap his feet in a warm cloth; this was followed by a shaking chill, after which warmth followed slowly, and with which appeared dulness of the whole head, except in the temporal region; complete absence of thirst, constant salivation, and inflammation of the skin of the left side of the lower jaw (second day), 3.
• Frequent shaking chill, often with chattering of the teeth, at various times, especially in the open air, lasting an hour; frequently followed by warm perspiration for a quarter of an hour, with a feeling of relief, .

CONDITIONS

• Aggravation.
• ( Evening ), Especially at 9 o'clock, on lying down, whereby vertigo, etc.; while walking, stitches in thumb; after going to bed, shuddering.
• ( Night ), In bed, chilliness; after midnight, coldness in left side; sweat.
• ( Acids ), The symptoms, 9.
• ( Open air ), Sensation of dryness in nose; general feelings, 9.
• ( Walking in open air ), Numerous symptoms, 8.
• ( Fat food ), Symptoms generally, 9.
• ( Movement ), Hiccough; pains over whole body; chilliness, etc.
• ( Rest ), Sticking in hip-joint.
• ( After sleep ), Pains in limbs.
• ( Stooping ), Headache above eye.
• ( Walking ), mostly in morning, on rising and in evening trembling of feet.
• Amelioration.
• ( After breakfast ), The symptoms, 5.
• ( Emission of flatus ), Confusion of head.
• ( Rest ), General feelings, 9.
• ( During work ), Feeling of weariness.

SUPPLEMENT: MERCURIUS CORROSIVUS. Authorities.

87 , W. B. Herapath, M.D. Lancet, 1845 (2), p. 650, an epileptic woman swallowed a scruple of the bichloride in solution; 88 , M. Wade, ibid., 1848 (1), p. 500, fatal poisoning of Mr. M., æt. twenty-one years, by rather more than a drachm; 89 , H. Gatch Carey, M.D., Med. and Surg. Reporter, vol. ix, 1856, p. 209, Mr. S., æt. twenty-three years, swallowed about 170 grains dissolved in Spirits of nitre, and died in thirty-six hours; 90 , John G. Bingham, M.D., Amer. Med. Times, vol. iv, 1862, p. 347, a child, æt. eighteen months, swallowed an unknown quantity, and died in twenty minutes; 91 , G. S. Galer, M.D., Philad. Med. and Surg. Reporter, vol. xxvi, 1872, p. 248, Mrs. S., æt. forty years, took over 1 fluid ounce from a bottle containing pure alcohol, with more of the substance than it could hold in solution; 92 , Q. C. Smith, M.D., Pacific Med. and Surg. Journ., Feb., 1875, p. 448, Mrs. W., æt. sixty-seven years, took about a tablespoonful of the strengh usually prepared to kill vermin, and died after twenty-three days; 93 , C. A. Libby, M.D., U. S. Med. Invest., New Ser., vol. vi. 1877, p. 72, a boy, æt. three years, swallowed an unknown quantity; 94 , R. T. Gore, Lancet, 1878 (1), p. 146, a woman injected some into her vagina; 95 , Maschka, S. J., 178, 238, a girl drank a large quantity; 96 , D. G. Woodvine, M.D., Pub. Mass. Hom. Soc., vol. iv, p. 149, a woman, æt. twenty-two years, took a fatal dose; 97 , Chas. T. Southworth, M.D., New Orleans Med. and Surg. Journ., vol. xvi, 1839, p. 675, Mrs. S., at sixty-three years, was occupied fifteen minutes in anointing with an alcoholic solution of the perchloride a bedstead infected with bugs.

MIND

• Inexpressible anxiety, 97.
• Indecent exposure of person; threw off the bedclothes, and attempted to walk about the room, when she was not able. She had, previous to taking the drug, been modest and retiring; now she seems to have no regard for herself. She cared not who was present when she desired to use the vessel, and threw off her clothing, as if no one were in the room; was cross and petulant, 96. [1130.]
• Coma (eighth day), 87.

HEAD

• Dull frontal headache was noticed first on the fourth day after taking the drug, and continued the same on alternate days, until the tenth day. On the tenth day the headache was continuous. She said the pain commenced down in the throat, and extended up through the Eustachian tubes to the frontal region. Fifteenth day, frontal headache, 96.

EYE

• Eyes protruding, 90.

FACE

• Features pallid (after five hours and a half), 89.
• Face flushed, 90, 97.
• Countenance pinched, anxious, and of a bluish-white hue (after half an hour), 91.
• First day, face dry and hot. Second day, face bloated. Fourth to seventh day, face much swollen and very red. Eighth day, much less œdema in face. Ninth day, face pale and slightly swollen. Tenth day, face swollen more. Twelfth day, face much swollen and red. Sixteenth day, face pale and features sunken, 96.

MOUTH AND THROAT

• Sloughing of the gums, lips, and tongue (fifth day), 87.
• Swelling of the gums and salivary glands, with profuse ptyalism, 94.
• Tongue was frequently thrust out, 90. [1140.]
• Breath had a gangrenous odor (twenty-first day), 92.
• Dark blood and brickdust-colored froth almost constantly dribbled from the mouth for several days before her death, 92.
• A white streak extended from the angle of the mouth to the lower edge of the jaw on one side, and the dorsum of the tongue and throat were also corroded, 90.
• The mucous membrane of the mouth and pharynx was destroyed, and blood slowly oozed from these surfaces, which were extremely tender, 92.
• The vitality of every part of the mucous membrane with which the caustic solution came in contact appeared to be destroyed, 89.
• Violent burning pain in the mouth, throat, œsophagus, and stomach, 97.
• Styptic, acid, metallic taste (after half an hour), 91.
• Ptyalism (third day), 87.
• Saliva copiously flowing from her mouth (after half an hour), 91.
• Ptyalism and swelling extending over the mucous membrane of the mouth, the inner surface of the cheeks, and the tongue, palate, and throat (second day), 97. [1150.]
• Third day, complains of very sore throat. It is swollen and much ulcerated. Inside of the cheeks and border of the gums much ulcerated. The ulcers are of a grayish color. Breath very offensive, so that it is very difficult to make a thorough examination. Fourth day, dry patch on end of tongue, the remaining portion being coated white. Fifth day, the throat feels better. Sixth day, throat feels sore, but not so difficult to swallow. Eighth day, throat sore, with pain on swallowing, extending up the Eustachian tubes. Mouth the same. Bloody mucus from the posterior nares. On the ninth day difficulty of deglutition much increased. Eleventh day, slight salivation, snapping noise in the throat when almost asleep, which wakens her. Twelfth day, no improvement. Thirteenth day, almost impossible to swallow; the throat is filled with glairy, sticky mucus, the ulcers appear much the same. Fifteenth day, sordes on the teeth, tongue dry, breath offensive. Sixteenth and seventeenth days, the same, 96.
• Burning and constriction of the throat (after half an hour), 91.
• Intense pain in throat and stomach (after a short time), 92.

STOMACH

• Much thirst, 97.
• Constant nausea (after five hours and a half), 89.
• During the latter stages, nausea and tenesmus were almost constant, the fluids consisting wholly or in part of blood, 89.
• Severe retching, and the head was thrown back, and tossed from side to side, 90.
• Violent retchings, with great pain (after a short time), 92. [1160.]
• Vomiting (in two minutes), 87.
• Violent vomiting of mucus and bilious matter, 97.
• First day, violent retching and vomiting of food and dark-looking matter; followed by yellow bile. Second day, vomited a great quantity of bile in the early part of the day; sensation of lump and pain in the pylorus; constant desire for cold water, which is very repulsive, and almost immediately vomited. Third day, constant nausea, with occasional vomiting of bile. The sensation of pain and lump in pylorus gone; thirst for hot or cold drinks, but nothing tastes natural, on account of a brassy taste in the mouth. Fourth day, no nausea. Fifth day, stomach sensitive to pressure; thirst for cold water in large quantity. Sixth day, much the same. Seventh day, swelling and pain in the pylorus, and hiccough. Eighth day, the sensation of pain and swelling in the pylorus gone; vomited once; great tenderness over the stomach and bowels. Ninth day, great flatulence after taking milk; the stomach very sensitive to the slightest pressure. Eleventh day, much the same. Twelfth day, anything liquid or solid produces distress and pain. Fourteenth day, cannot take anything into the stomach: She remained thus until death, on the seventeenth day, 96.
• Spontaneous vomiting supervened almost instantly, 89.
• After the first hour, the fluids thrown up consisted of those taken to abate the thirst, which was not immoderate, mingled with blood (after five hours and a half), 89.
• After oil and milk were taken, she vomited and passed bloody matter from the bowels; and these symptoms, accompanied with pain, continued with greater or less severity until death, 92.
• Vomiting occurred in a few minutes, the fluid ejected consisting of a white froth, with a considerable quantity of blood. Complained of much pain in the region of the stomach. Countenance pale and anxious; surface of body generally cold, especially the extremities; pulse scarcely to be distinguished; tongue dry, 88.
• Constant pain along the whole length of the alimentary tract (twenty-first day), 92.
• Burning, griping, and tearing pains of the stomach, accompanied by deathly nausea, but by no vomiting (after half an hour), .

ABDOMEN AND STOOL

• First day, sharp pain, with rumbling in the bowels and profuse bilious discharges. Second day, a great many bilious and slimy stools during the twenty-four hours. Third day, frequent slimy bilious stools in the morning early, with tenesmus; no stool in the afternoon; bowels are a little sensitive to the touch, and are very flat. Fourth day, no stool. Fifth day, three bilious, slimy stools in the early part of the day; bowels sensitive to pressure. Sixth day, diarrhœa continues, but is growing less. Seventh day, a good many dark-brown and slimy stools day and night, which continued until the thirteenth day, when it was less frequent, until the fifteenth day, when two hæmorrhages of the bowels occurred within fifteen minutes of each other, after which the discharges were involuntary until death, 96. [1170.]
• Constant disposition to evacuate the rectum and bladder (after five hours and a half), 89.
• Diarrhœa (first and second day), 87.
• Violent purging, 97.
• Dysentery and tenesmus (fifth day), 87.
• The frequent small, bloody, alvine discharges emitted an intensely putrid odor, so offensive that the attendants could scarcely remain in the room (twenty-first day), 92.
• About forty minutes after taking the poison, the patient passed a natural motion from the bowels, which was followed by a considerable quantity of fluid blood, 89.

URINARY ORGANS

• Urine suppressed (third day), 87.
• Three half pints of urine and blood were evacuated, the latter fluid predominating (after about forty-five minutes), 89.
• Second day, a very small quantity of urine was passed, after which there was complete supression of the urine for five days. Eighth day, a good deal of acute pain in the region of the kidneys; passes a small quantity of urine. Specific gravity 1013; reaction acid; looks as if a few drops of milk were stirred in the urine. The common tests of heat and nitric acid show an albuminous deposit. Squamous epithelium in the deposit on the eighth day. Ninth day, has passed no urine for twelve hours, and suffered much acute pain in the kidneys. Tenth day, urinates more freely than for several days. Specific gravity 1010. Examination of the sediment under the microscope reveals what appears like a granular cast, urine still albuminous. Fifteenth day, until death, involuntary discharge of urine; great tenderness to pressure in the region of the kidneys, 96.

SEXUAL ORGANS

• Intense pain in the vagina and abdomen, with a copious discharge of thin watery mucus, 94. [1180.]
• Menses reappear for a day or two, she having just completed her regular menstrual period at the time the drug was taken. On the thirteenth day the menses reappear slightly, 96.

RESPIRATORY ORGANS

• Second day, loose rattling cough, with almost complete aphonia; raises a good deal of grayish-looking and salty-tasting phlegm. Fourth day, loose rattling cough. Sixth day, voice improving. Eleventh day, cough loose and rattling. Fifteenth day, breathing short. Sixteenth day, sighing respiration, 96.
• Short and laborious respiration (after half an hour), 97.
• Great dyspnœa (after five hours and a half), 89.
• Respiration embarrassed (ninth day), 87.
• Respiration irregular and sighing (twenty-first day), 92.

CHEST

• Chest often violently expanded, 90.
• Congestion of the lungs (ninth day), 87.

PULSE

• The pulse was small, weak, and beating 60 to the minute (after half an hour), 91.
• Pulse quick, small, and contracted, 97. [1190.]
• Pulse 120, very weak and irregular (twenty-first day), 92.
• Pulse at the wrist perceptible only occasionally (after five hours and a half), 89.

EXTREMITIES

• Myalgia of the thighs; coldness of hands and feet on the ninth day. Sixteenth day, lies with feet drawn up, 96.

GENERALITIES

• Jactitation and trembling (eighth day), 97.
• Convulsions (eighth day), 87.
• I found him in the sixth convulsion, fearfully distressed, and every part of the patient was drawn up, his feet, legs, arms, and hands were closely contracted, the hands being so clasped that it was impossible for me to open one finger; face flushed a bright scarlet, cheeks and forehead hot; but around his mouth it was marble white, and under his eyes it had a purple shade; pupils dilated; eyes rolled up so that you could only see the pupils by pressing the lid up as far as possible. He remained in this condition about five minutes. After remedies he vomited fresh blood, perhaps half a teaspoonful each time, mixed with the egg. After six hours the pulse was 160, face flushed, tongue dry, with a very red streak in the centre, and very thirsty. About 12 o'clock that night blood began passing the bowels, and shreds of membrane, with great tenesmus. In the morning the stomach and bowels were sore to pressure, 93.
• She fell to the ground in a faint, became collapsed, insensible, with a very small pulse, 93.
• First day, unconscious; pulseless at the wrist; constant restlessness and tossing about. Second day, fully conscious, but spoke with difficulty; pulse 120; myalgia. Third day, continued restlessness; pulse 120. Fourth day, pulse 100. Sixth day, pulse 80. Seventh day, pulse 88. Eighth day, pulse 88, refuses to talk. Ninth day, pulse 100. Tenth day, myalgia. Eleventh day, pulse 96. Twelfth day, pulse 100; myalgia. Thirteenth day, pulse 88. Fourteenth day, pulse 100, Sixteenth day, pulse not countable; is not inclined to talk; great debility and emaciation. Seventeenth day, had a fainting spell; heart stopped for a few seconds, her eyes half closed, and died on the seventeenth day after taking the poison, 96.
• Restless (after five hours and a half), 89.
• In a state of almost hopeless collapse (after five hours and a half), 89. [1200.]
• Prostration (ninth day), 87.
• Extremely prostrated (twenty-first day), 92, 97.
• Great prostration and violent pain (fifth day), 87.

SKIN

• First day, the had a very dry, harsh feeling to the hand. Second day, great coolness of the surface all over the body. Third day, skin warm all over, but hottest on the face. Fourth day, high fever. Sixth day, great itching of the skin, which looks dry and shrivelled. This itching, with variations in the temperature, continued until death, 96.

SLEEP

• First and second days, scarce any sleep day or night. Third day, slept a little during the daytime. Fourth day, slept better. For the next seven days she had short naps and unpleasant dreams. Fourteenth day, had very restless nights for the last three nights. Seventeenth day, sleeps with eyes half closed, 96.

FEVER

• The whole surface was cold, and bathed in a profuse clammy sweat (after half an hour), 91.
• Skin, even when dry, felt cool to the touch (twenty-first day), 92.
• Artificial heat was required to keep her feet and limbs warm, 92.
• Surface and extremities cool (after five hours and a half), 89.
• Begged for cold water often to drink, and to be poured on her body and head, and expressed partial, temporary relief when her body was sponged with cold water; saying without water, she was burning up, inside and out (twenty-first day), 92. [1210.]
• Febrile excitement in the evening (sixth day); continued (seventh day), 87.
• Cold sweats, 97.