Stillingia silvatica

από Richard Hughes & Jabez P. DakeA Cyclopaedia of Drug Pathogenesy

Volume IV — Main text

STILLINGIA.

StUnH^a tyhfotka, Willd. Queen's root, queen's delight, yaw.root, silver-leaf. Nat. Ord., Buphorbiacta.

I. Prwings. — i. a. Dr. E.B.NiCHOLLS,xt. 25, well, but for a chronic cutaneous afTection, took, Dec. i6th, 1865, at 8.30 p.m., 10 dr. of tinct. In ao m. dull heavy pain in forehead, which after a time became a feeling as if a heavy substance was pressing on front part of brain ; pain then became very sharp and darting, almost unendurable. Therewith dizziness ; heavy pain in bypogastrium ; sense of constriction in larynx, and smarting and stinging in fauces. This last subsided after an h., leaving feeling of rawness. At >i had sharp darting pains through chest and shoulders, very severe ; boring pains in region of heart ; pulse irregular ; distressed feeling with dull pain in head and dryness of fauces. 17th. — At 10 a.m. took lo^dr. Slight return of former symptoms; smarting, stinging, and dryness of fauces all d. At 9 p.m. repeated dose. i8th. — Slept well ; bitter taste on awaking. At 9 a.m. repeated dose. Felt miserable all forenoon, pains in head, eyes inflamed and «watery, soreness of muscles all over ; feels as if he had taken a severe cold. At a p.m. again 10 dr. Immediate aggravation of symptoms; throbbing and dizziness or head ; smarting and stinging pains in fauces; oppression of chest ; pulse 90. 3, puke 100; violent frontal headache; slight perspiration ; stinging darting pains in race ; constriction of larynx ; colicky pains, violent about umbilicus. Took another dose before retiring. 19th. — Repeated dose at 9 a.m. and s p.m. No marked effects from first ; after second, headache and smarting in fauces. 20th. — Took I o dr. in m. Darting pains through thorax ; tickling in throat and short hacking cough, aist. — Cough continues, at times quite severe. X3rd. — Violent burning, smarting pain along urethra for s h., aggravated by micturition (which was difficult), and dull pain in region of kidneys. This recurred at times up to a8th ; no discharge.

b. On Jan. 4th, 1866, took 10 dr., at 10 a.m. and z p.m. After second dose slight headache, dryness and tickling of fauces; short hacking cough. At 11 p.m., on passing urine, there was sharp pain in glans penis, extending up urethra, so severe as to cause perspiration to start. Took another 10 dr. 5th. — Awoke with dull pain across kidneys and sharp pains in penis; short hacking cough; fauces inflamed. Pain continued all d., and he discontinued the drug ; but it had not entirely subsided (nor had the cough) on the 10th. {Traits.^ Amtr. Inst, of Horn., 1869,

P- »94-)

s. a. Dr. Thos. Eckles tested his urine on several occasions before commencing drug. Sp. gr. ranged about 1023 ; on one occasion, after standing 24 h., a flocculent mucous sediment was deposited. On Nov. 1 6th, 1866, began proving tinct., commencing with 10 dr., repeating it 3 times a d., and at each repetition increasing dose till at last it reached a ublespoonfiil. After a short time bowels became very loose

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and irregular, but artrrward$ constipated, with nausea and a slow irregular pulie while lying down. Suh<>cqMently he experienced irritation of fauces, slight headache, and sensation as if diarrhoea would set in. Appttitc was increased j there was coidnen of whole body on going to bed, though after a short time whole surface seemed gently perspiring, with continuous feverish heat ; slight but persistent headache, mostly in vertex and forehead ; pulse full but very irregular; tongrue slightly while, coated ; bruised feeling of trachea on pressure ; inflammation of I. tonsil, lasting several d. ; severe pain in or near r. kidney, ot short duration } at times dull pain in r, side of head; excessive itching on skin below knees, though no eruption wat perceptible. This last continued Tor 8 weeks, greatly aggravated by exposing parts to the air, especially if cold.

b. Jan. 19th, 1867, took lo dr. at 6 a.m., 12 m., and 3 p.m. j 15 dr. at 6 and 10 p.m. On going to bed felt slight uneasiness and tickling in trachea and bronchial tubes, which was worse on rising next m. loth. — Took 15 dr. 5 times during d., and 20 dr. at n. iiit. — Chest and throat feeling about well. Took la At. 6 tiroei, but experienced only a general feeling of malaise, iind. — After a good night's rest felt somewhat better. Took 10 dr. 5 times. Towards e. tickling sensation, producing an excessively dry spasmodic cough, ijrd. — Took 10 dr. 4. times, Cough looser and deeper, zivth. — Took 20 dr. at 6 a.m., noon, and bedtime. Had, a.m., slight lame feeling, seemingly in cartilages of trachea. At 6 p.m. griping in epigas. triuni, soon fallowed by diarrhoeic evacuations, with abundant flatus. 25th. — Took 25 dr. at 6 a.m. Continued feeling of impending diarrhoea. 26th. — Took too dr. No further symptoms. (During the proving a pustular eruption, that had persistently remained for a month, rapidly cleared away.)

e. Jan, 5th, 1869, took 10 dr. of a fresh tinct. (i part of root to 10 of dilute alcohol). 6th. — Took 10 dr. after breakfast, and half a tablespoonful before dinner. 7th. — Same dose 3 times. P.m., an abundant white sediment appeared soon atier urine was voided. 8th. — Felt quite weak ; general sense of malaise ; pulse about 90, weak and very irregvilar. Took half a tablespoonful after breakta.tt and dinner. Noticed during d. that he would have "spells" of feeling as though room was (oo warm; would then break out into general perspiration. Pulse during these »pel It was regular. 9th. — Pulse very irregular. After breakfast took half a tablespoonful, and repeated this after dinner and at bedtime. Towards noon pulse became more regular, and continued so till n. Stool at 1 p.m. f 19 h. over regular time), with pain in rectum and anus. Aching of legs in e. lofh. — Took a tablespoonful. No Uirther symptoms, save on 12th general malaise with irregular puli>e, and on 1 jth bruised feeling in sphincter ani.

d. Jan. 17th, on going to bed, took 5 dr., and on iSth, 10 dr. 4 rimes. Till after Ia»t dose experienced no symptoms; but previous to going to sleep had burning sensation in 1. car, on which next m. appeared a vesicular eruption. 19th. — Took to dr. 3 times, and 15 dr. twice. Felt severe irritation of bronchi .nnd bruised feeling of trachea. 20th. — Continued taking drug, increasing dose to 100 dr. Genenil malaise about bedtime, but after sleeping all n. felt somewhat better in m. 5 tongue slightly coated. Totvards e. (list) tickling in trachea, producing verj' dry cough, which later became loose and deep. Griping in epigastrium, followed by diarrhoeic stool. {Ibid.)

  1. J. M. Cunningham, set. *i, in goo<l health, Proved tinct. for unknown number of days in Nov., 1867, taking 15 dr, m. and e. "The first symptom experienced which I thought might be attributable to the action of the drug was burning itching of legs below knees, worse on exposure to air. Heartburn was constant during proving, commencing about 2 p.m. and continuing till bedtime. Stool wtis delayed several h. while under influence of the medicine." {Ibid.)

  2. E. H. Ingram AM, *t. ,^5, in good health save for ready gastric derangement, from Feb. istt0 7th, i86S,iook ic dr. of tinct. 3 times a day. On 3rd felt sleepy in e. much earlier than usual. 4th.'— Same drowsiness in r., and alw by spells during d. } slight headache, running from anterior part of temples, pain dull and constant. 5th. — Catarrhal discharge from nose, at first watery, then muco-purulcnt ; nostril sore inside. Urine 30 oz. (average is 35), high-coloured, with brick-dust sediment. 6th. — Slight frontal headache; urine 40 07., high-coloured and inclined to foam ; some catarrh, small abscesses in I. nostril. 7th. — Drowsiness. Urine 45 oz. On 8ih began taking roo dr. per d. instead of 30 (does not say how long he continued

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|it). Headache in c, a current of pain flowing from median line of forehead to

ooripita] process and 1. certlxllum. Lew sleepy this e. Urine 38 or., tolerably

(lev. though containing some brick-dust tediment. 9th. — Same headache; mind

duQ and stupid ; slight retraction of 1. testicle; urine 40 01., thick and milky, con.

tiintog much chloride of Mxlium. loth. — Urine 58 oz., tolerably clear, but inclined

to form bubbles a* discharged. Head and mind the same. nth. — Slight, constant,

dull hradjcbe through temples j depression of spirits; tongue coated heavily, yel-

lowiih white; ipelb of neuralgic (ootharbe; return of nasal catarrh, discharge more

watery than before; urine 40 01,, almost clear, nth. — Same headache a» yesterday,

pun umler malar bone, extending transversely through face ; drawing pain in 1. knee,

affecting gi\irotnemius and biccp<> muscles; depression of spirits and gloomy fore-

Iwdingi; longue white, tjfh. — Urine jj or.; head same. 14th. — Head same,

with Ion spirits, stupidity, slight nausea, tongue coated white. 15th lo «8th. —

nHnehunow returned to normal quantity. Headache through temples continues

to trouble at intervals. (IbU.)

i- R. F. C — , Nov. 6, 1869, It 10 a.m. took 5 dr. of tinct. in Jss of water. In

i *. iching pains in r. leg and r. foot over instep. After 8 to 10 h. pains as before,

aB<JtUoin r. hip and 1. foot. After retiring same pains in back of r, leg. 8th.^

Tool J dr. of vamc in forenoon, and 5 dr. of 3rd dil. in c. Two h. after last dose

•«Tfrt pains in r. foot over instep, increased on standing and attempting to walk.

9th.— In m. pains in sole of r. foot and in leg. P.m., while driving, pains in I.

to»tr anterior third of leg. While sitting, some pain in 1. lumbar region, shooting

from behind forward ; later, white riding, pain in both hip-joints, worse from bending

|>wk"»rds or forwards, increased after getting out and walking, with stiffness of

joints. While in house pain in 3rd toe of r. foot. While walking, pain in meta-

tarul joint of great toe, running back to heel, in both feet. Pain in both outer

inalleuli. lolh. — Pain in r, elbow, forearm, and wrist, aggravated by motion ; pain

10 fmgtr.joints ; aching pain on outside ot r. thigh and Ttg, running down to foot.

(Dr. M. PrestoVs provings, in Trans, of Penns. State Horn. Mtd. Soc., 1870-1.)

<. M. P — took same dose on same d. and h. as No, 5, while suffering from gmi MTencss of muscles of extremitie« caused by severe exercise. After 7 to 8 b. MMCona was much increased, and great aching of extremities w.ts experienced. 8lh. ^•In m. took 5 dr. In e. pains in r. elbow and leg, of aching and pulsating -■••-•. with soreness; aching pains in back, extending down thighs and legs; u: along 1. clavicle and in shoulder. At 8.30 p.ra, took 10 dr. of 3rd dil. jud aching on olecranon, uninfluenced by motion. 9th. — Aggravating 1 in 1. elbow, extending towards shoulder and hand, as thougli bones were sore would separate ; slighter pains, of like character, in r. elbow ; aching also in I. rval Mid metacarpal bones. These pains are temporarily relieved by change of tion. Slabbing io r. knee. On Dec. 6th Dr. P. notes, " Symptoms continue.

some of them nearly every d." {Ibid.)

J, W. O. G — , Nov, 8ih, at 8.30 p.m., took 5 dr. of 3rd dil. In 1 h. dull heavy

tion in r, thigh and leg. 9th. — At to a.m. repeated dose. In i h. sharp

td of I. elbow, increated by hanging arm down. lotb. — 9.30 a.m., sharp

pain* in upper third and inner side of forearm, aggravated by letting limb

Ml, and relieved by pressure. 4. p.m., took 10 dr. of same. 5, sharp shoot-

MiBii in both armk, from middle third of humerus to finger-;. 10, severe sharp

jofing in r. side of frontal bone, running down to eye. {Ibij.)

For Dr. Taber's provings see Appendix.

Volume IV — Appendix

STILLINGIA. (Gee vole, p133)

1, 8, Aug. toth, 1874, 10 ams chewed piece of fresh root torface had been deprived of is epitheliom, Causing intense buraing sensation on tevere choking sensation resembling globurhysericus} imporile to dislodge it Thad recoure to nox vom, and chelidonium maj, ‘Sught burg sensation ia stomach, at 2 pan, baving had severe regurgitation of food and actual vomiting of ingesta for sometime afer cating. (FF. Tanth, Ohio Med and Surg. Rep.yin tt)

: Mrs. S~ chemed piece of fcth rot on tithat 8am. At ro. felt ick and 4qualmish at stomach j at 12 bowels began to move, bad 6 stools in 2 hy Ast 9 Sopiony, last j scanty, of white colour and dyenteric Bowls fel asi they would ‘move ngainyfevere ramps in stomach and both hypochondria both ovaries pained fer very weverely. Reliced of sick xfomach by peeae. Had another soo), wit and resembling cords (* Nearly all the symptoms of proving T made in”73 have

l»e«n rerified in this, only not to so marked a degree because I did not continue the prCTing.") (IbU.)

to. Zanthus Lype, set. 40, April 18th, 1.10 p.in.ttook 40 dr.; at 4.]0 repeated

dose. He felt slight warmth of fauces j toHCTie felt rough and sore j had salty taste

in mouth. Took no more after this, had slight borborygmus with escape of flatus

duringd. Slept well during n., but felt languid, having great desire to sleep, next d.,

•»«r«th dull heavy feeling all over, especially in both leg-.; fell sore from lop of head to

■ol« of feet j didn't want to move ; wanted to go where he would not be annoyed ;

profcvsional duties irksome ; head felt heavy; perfect relaxation of all the muscles of

neck; brain felt too large for skull; required considerable exertion to keep eyes open.

I Onatsf, at ji a.m., took 40 dr. ; no symptoms. At j p.m. took 40 dr.; in 15 m,

f had sharp darting pain in r. ankle-joint, outcrr part j darting pain in I. temporal

•^gioB, as if a piece of wire or some sharp pointed instrument had been thrust into

te-mples; sharp darting pain in I. hypochondrium, beginning in ascending colon,

paaing through transverse into descending, followed by escape of flatus. At 6 p.m.

^^ taken with severe rumbling in bowels, as if diarrhoea was about to set in, re.

AJered by escape of flatus. This lasted about 1 h., and was relieved by smoking,

^a »»nd, after fine night's rest, above symptoms came on again, with two copious,

**^fid, frothy, bilious stools, with some tenderness in bowels and burning sensation in

*iiui, which subsided after 4 h., leaving uneasy feeling in rectum. On 13rd, at

/*' a.m., took 40 dr., which occasioned sharp darting pains in bowels; great warmth

*P face, as in catarrhal fever ; sharp darting pain in sinciput, extending to occiput.

■^* *-3o took 50 dr., and at 4.40 the .same. At 6 felt considerable heat in fauces,

^nich gradually increased till throat became very sore. On 14th, at 7.50 a.m., took

*^ dr., which was followed by a rough dry feeling in mouth. At 10.30, took 60 dr.,

*1d at X p.m. had a loose, papescent, bilious evacuation, accompanied by loss of

Pl>ctite ; felt weak and emaciated, as if he had lost all strength and energy ; had

*^«n\iderable rumbling in bowels, and faint empty sensation in stomach. On 15th,

^•» took 70 dr. i at 10. jo had ^harp darting pain over 1. eye, with slight lachrymation

/^•^Ij both eyes, more profuse xvhen reading; r. eye affected more than 1, Sharp,

^"T^ing pain in r. occipital protuberance. At 4 p.m. took 70 dr. Had didl pain m

. **vicuUr space. At 10 great distress in epigastrium, as if there were a ball or lump

?** throat, so that he could not get to sleep till after 1 a.m. Awoke at 6 with sharp

^•"ning sensation in r. nostril, and "^sharp darting pain in both kidneys, first in I. and

^n in r., with dull heavy pain in I. testicle. On 16th, 8 a.m., took 90 dr. j dull,

vy aching pain in 1. testicle. At 4 p.m. took 90 dr.; quantity of urine materially

*»«: leased; clear transparent urine, scalding a little in passing. On iSth, 10 a.m.,

'^'^k too dr.; symptoms about same as those last noted, save that he noticed an in-

^*^a4e in the quantity of urine; constant rumbling in bowels, relieved by escape of

"^^us. On 19th had a loose stools, following each other at short intervals, with

^at tenesmus and burning at anus, which lasted | h. ; urine scalding in passing,

_**:h uneasy sensation at neck of bladder, feeling as if it were inflamed; urine quite

.^^^^ar. At 3 p.m. took no dr., and at 4.10 haxj pain in r. shoulder-blade, running

^J* neck; dull aching pain in calves of legs ; raw feeling in chest, whole length of

P ^■rnum. " During whole time my sleep was sound and natural, with no unpleasant

^ clings after awaking in m, On m. of 19th, as usual, I had an evacuation imme.

J * ately after breakfast, the call being urgent. On voiding stool had severe burning

*^ anus, considerable tenesmus ; slight dull pain in tendo-Achillis, I. foot; uneasy

^ nations in popliteal space, both legs; dull feeling in calves. For several d. after

■^king the last dose had severe attack of piles, the first I had ever suffered. The

^^tack lasted several weeks before I was entirely relieved by the use of proper

*'«tm(dies." (IbU.)

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