Clematis erecta

Volume II — Main text

CLEMATIS .

Clématis erecta (vel recta), L. Upright virgin's bower. Nat. Ord., Ranunculacea. I. Provings.-I. HAHNEMANN, Chronic Diseases, part iii of original, vol. of translation. Contains 283 symptoms from self and 5 others, with 6 from authors . 2. F. ALB, surgeon, æt. 53, when 33 had fluent hæmorrhoids ; on their disappearance had for 7 months diabetes insipidus. Two years ago had several severe attacks oflumbago, which was cured in 3 months by sulphur internally, and in the form of sulphur baths ; has had inguinal hernia from a child. Aug. 13th, 5.30 a.m., took 10 dr. Ist dil (2 to 100) . 4 p.m., full and tense feeling in abdomen as after a full meal, increasing till 9 p.m.-14th, 6 a.m., 15 dr. 7.30 a.m., impaired hearing for 6 m., confusion of head until 2 p.m., relieved by open air, as if coryza were coming on, dry feeling in nose, appetite increased, cross humour. 10 p.m. , 15 dr.-15th . On waking, drowsiness and heaviness of limbs. On rising, intoxicated confusion ofhead, impaired hearing for h., accompanied by ringing in l. ear, dry nose, jerking pain in r. upper carious molar, that had never before given any pain, lasting 2 m., and recurring after 6 m., removed by rinsing mouth with cold water. After breakfast sneezed 8 times, followed in 6 m. by discharge of clear water from 1. nostril and such sleepiness he must go to bed. After sleeping 24 h. giddiness and constant sleepiness, not removed by open air, lasting till 2 p.m.; weariness, especially in thighs and knee-joints, cross disposition, indisposed to think, at same time forcing towards r. inguinal canal with frequent protrusion of a hernia (which he had had since childhood) and pressive pain in r. spermatic cord. 5 p.m., more cheerful ; e., very hungry.- 16th. Same symptoms, but milder.- 18th, 6 a.m., 8 dr. mother tinct. As no symptoms occurred, took at 10 a.m. 10 dr. of mother tinct., but as no effect was produced, at 10.30 p.m. took 10

dr.-19th, 6 a.m., 15 dr.; 10 a.m., unusual gaiety lasting till 4 p.m. then sudden disinclination for work, cross humour, weariness of limbs, increased feeling of warmth, especially in face, quickened pulse, 82, dull pain in frontal protuberances. After 5 p.m. irresistible sleep when reading. Woke up at 7.30p.m.; return of heaviness and weariness in lower extremities, and after taking some soup the sleepiness returned, so that he had to go to bed at 9 p.m. Woke at II withjerking-tearing in the place where a l. upper wisdom tooth had been extracted 7 years previously ; the pain spread to 1. zygoma and temple, which lasted till 2 a.m. and returned after a sleep of 2 h. for a short time.- 20th. Woke with weight in head, itching in anus, hæmorrhoids swollen and moist with mucus, hurried call to stool, evacuation pappy, accompanied by much flatus, burning while urinating behind fossa navicularis, urine dark yellow, weariness. Took 22 dr. Cross humour, pressure in both frontal protuberances, frequent violent sneezing, watery discharge from nose, itching on hairy scalp on 1. side of crown, an itching papule above r. eyebrow. 11 a.m., feeling of weight in l. testicle, tensive sensation in r. spermatic cord, rumbling in abdomen, extending to hernia, and in h. another pappy stool. 10p.m., in bed, violent itching in hæmorrhoids, and slight mucous discharge. After reading in bed forth. the above toothache on both sides ; fell into a dreamful sleep at 1 a.m.- 21st. On waking, both teeth felt too long, gums swollen , pale ; the pain extended to canine teeth on both sides, making chewing impossible ; Merc. sol. v. removed this . (Zeitsch d. Ver. d. hom. Aerzte Oesterr. , ii, 278.) 3. AMALIA ALB, æt. 18, from 2 to 10 years had every autumn an attack of croup, and from birth had paralysis of r. side ofjaw with occasional lachrymation ofr. eye. Menses regular since 15.-July 13th, 6 a.m., 10 dr. 1st dil. 10.30 a.m., flatulent distension of abdomen with rumbling. Little appetite for dinner. 2 p.m. , frequent yawning with drowsiness, which went offin open air. 7.30 p.m., transient chill over shoulders and back, full feeling in pit ofstomach, drowsiness.- 14th , 6.30 a.m., 15 dr. 11.30 a.m., digging and pressure in r. temple, forehead, and zygoma, anorexia. 2p.m., irresistible sleepiness and sleeptill 5 p.m. On waking cross, furious anger, weakness in legs, drawing in wrists and knees.- 15th, 5 p.m., same headache as yesterday. 1 h. later consistent stool, frequent discharge of normal urine.-16th ., 6 a.m., 20 dr. 10 a.m. , desire to work and cheerful humour till 2 p.m.,when she became sleepy and disinclined for work. 7 p.m., sudden drawing,jerking, tearing and shooting in l. lowersound canine tooth, which soonextended through whole row of teeth, and went to and fro, relieved by cold water in mouth .- 17th. The menses, previously always regular, came on 10 d. too soon, but lasted only 2 d.-19th, at noon, violent griping in abdomen, especially below navel, lasted h. and then a pappy stool with much flatus.- 20th., 6 a.m., 10 dr. mother tinct. Tearing-digging toothache in all r. upper teeth, semilateral frontal headache. II a.m., nausea, with inclination to vomit, no appetite for dinner. 6 p.m., while walking in open air chill over shoulders, followed by heat for h., slight drawing in both wrists and insteps. 9.45 p.m., violent itching on both forearms and upper part of abdomen, making her scratch, which caused burning, a red miliary rash on itchy parts. Restless sleep at n., with

occasional moaning.-21st. The eruption appeared as small papules, the itching changed to burning. The eruption was worse about navel, some vesicles among it ; this lasted till the 23rd, when it desquamated with violent itching. 3 p.m., traces of menses appeared, which ceased by noon of following d. Since then well . ( Ibid, 280.) 4. J. CZARY, veterinary surgeon, æt. 40, in his childhood had catarrhal bowel complaint ; 10 years ago pneumonia, otherwise always healthy.-June 7th. I h. after breakfast 5 dr. tinct. No symptoms. -8th. 10 dr. after breakfast. After h. gaiety, tongue dry, thirst. After dinner felt well. 4 p.m., firm stool.-9th. 15 dr. after breakfast. After I h. transient gaiety, followed in h. by persistent prostration of mental powers ; slight drowsiness after dinner, no stool.roth. 20 dr., same symptoms, no stool, formerly bowels regular.- 11th. 25 dr., after I h. great excitement, disinclination to mental work, irritability ; some drowsiness after dinner. 3 p.m.,a firm stool. -12th. 30 dr.- 13th. 35 dr., same symptoms.- 14th. 40 dr., soon felt uncomfortable, irritable, unfit for mental work, dryness of mouth, increased thirst. After a plentiful dinner sleep for 2 h. 5 p.m. , a firm stool with straining. Observed a small swelling of submaxillary gland which increased till 22nd, then went off gradually. Stools till 23rd every 3 d. After this the normal state was restored. (Ibid.) 5. Dr. M. EIDHerr, æt. 29, was never seriously ill. -July 8th, 5 dr. mother tinct. I h. after breakfast. After I h. felt excited, gay, stronger than usual, and with more inclination for reading and thinking. This lasted h., soon followed by weakness of mind. disinclination for reading and thinking, and a kind of intoxicated state, perspiration, pulse quickened by 12 beats, and thirst ; in 3 h. these symptoms gradually went off.-9th, 8 a.m, 10 dr. After h. a semi-liquid stool. 9 a.m., increased cheerfulness and inclination for mental work, perspiration and itching of skin. 10 a.m., felt exhausted, anxious, sad, irritable, was vexed at trifles, and lost all desire for mental work. This lasted till noon, the itching till 4 p.m. Appetite for dinner increased. 2 p.m., drowsy.- 10th, 8 a.m. 15 dr. Same symptoms as yesterday. 3 p.m., drowsy and fell asleep; no stool. Sleep at n. disturbed by confused dreams .- 11th. Woke with confused head. 3 p.m., again drowsy. 9 p.m. , hard stool, with straining.-12th. Well.-13th, 8 a.m., 20 dr. 9a.m., great gaiety, felt very happy, mental power increased ; 1 h. later sad and very cross, no inclination for mental work, itching all over body, felt quite weak. This state lasted till 10.30 a.m. At I p.m. had only slight confusion ofhead. Appetite increased. 7.30 p.m., very sleepy, slept for 2 h., sleep at n. very restless, full of confused tiresome dreams. Urine passed at n. scanty and dark red.- 14th. Woke at 6 a.m. with confused head. 8 a.m., 25 dr., same symptoms as yesterday.-15th and 16th. Nothing but great drowsiness after dinner. Smoking, usually agreeable, caused nausea and vomiting. E. hard stool.- 17th, 8 a.m., 30 dr. Same symptoms.- 18th, 8 a.m., 35 dr. Low spirits, anxiety and general weakness after a few h. Sleep afternoon and n. not refreshing, constant disinclination to get up. No stool to-day or yesterday.- 19th. 40 dr. same symptoms. The accustomed cigar again caused nausea and inclination to vomit. Until 24th, though he took no medicine he

had continued disinclination for mental work, great drowsiness, long unrefreshing sleep, dislike to get up, increased appetite, constipation, and low spirits. The lymphatic glands in r. groin swelled to the size of hazel nuts ; this swelling was gone by the 27th ; the cigar still caused nausea . From the 24th the stools, which had been constipated, occurred several times a day, loose, without straining.-Aug. 31st., 8 a.m., 5 dr. 1st dil. 10 a.m., increased warmth of body, thinking power and inclination for mental work increased. This lasted h., then the same copious perspiration, prostration of mind and body, disinclination for mental work ; feet heavy , walking soon tired him ; head confused, pulse quicker by 10 beats, occasional lightning-like stitches in various parts of skin. 12.30 p.m., only confused head, which disappeared in open air.- 14th, 8 a.m., 10 dr. 9 a.m., great cheerfulness, movements easy, skin perspired agreeably, increased thirst, flush, redness in face, pulse quickened by 12 beats. 9.45 a.m., hard stool, perspiration, vacancy of head, heaviness of limbs, a sort of intoxicated state. Pain in forehead lasting till e.- 15th, 8 a.m. 15 dr. Same symptoms as yesterday. Towards e. slight drawing and transient stitches in r. ear, cheek, and side of neck ; moving head increased pain.-16th, 8 a.m. , 20 dr. Cheerfulness for a short time was followed by discomfort, crossness and anxiety up till 1 p.m. Frontal pain till 5 p.m. 3p.m., drawing in r. ear, cheek, and neck, with occasional ringing in ear, pulse increased by 16 beats. E., a hard stool with great straining. At n. many confused dreams, waking with a start ; the drawing pain still felt and accompanied by tenderness of parts to touch.-17th . Woke with dull headache and great desire to go to sleep again. On rising the drawing pain was increased, and turning the head extremely painful. 8 a.m., 22 dr. , no ringing in ear, drawing pain gone out of cheek but worse in neck and under chin ; it was aggravated by touch, turning, and especially bending back head, a slight swelling under r. lower jaw. Saliva increased, urging to stool without effect.-18th, 8 a.m., 24 dr. After h. hard stool with straining ; depression of spirits, great sensitiveness to external impressions, slight irritability and anxiety. The pain in r. side of neck made movement of head in any direction painful, the r. submaxillary gland was swollen, the l. painful but not swollen. Saliva increased, r. inguinal glands bigger than l., painful after walking.- 19th, 8 a.m. 26 dr. Same symptoms as yesterday.-20th, 8 a.m., 28 dr. R. submaxillary gland not so painful, surrounding swelling less, but gland itself enlarged, 1. more painful, not swollen. No stool.-21st, 8 a.m. , 30 dr. Pain in r. submaxillary gland gone, but gland still swollen; 1. also less painful, very slightly swollen. Inguinal glands as before. Saliva increased.-22nd. 32 dr.-23rd. 34dr.-26.36 dr. No more new symptoms. The glandular swellings and salivation all gone by the 30th.6. Dr. (Ibid., 283.) I. R. GRÜNBERG, æt. 40, subject to catarrhal affections in spring and autumn. When he began proving was still suffering from remains of one of his usual spring catarrhal attacks.-May 8th, 6 a.m. , 5dr. mother tinct. After 24 h., confusion of head and dull feeling in it. h . later, feeling of pressing as from a hoop round head ; later, increased confusion ofhead with staggering ; flush of heat and pressive

pain all over head. 10 a.m. , heaviness and heat of head, and warm feeling in rectum, followed by urging to stool. 10.15 a.m., head heavier and hotter, swayed from side to side, so that it could not be kept upright, vertigo on entering a room, must lean head against something, and support body, which trembled, relieved in open air, but staggered in walking as if intoxicated. 10.30 a.m., heat of face, circumscribed redness of cheeks, heat externally in sacrum spreading from centre toperiphery as ifa warm poultice were there. 11.30 a.m., profuse sweat of head and sacrum, both when walking and when seated, till 2 p.m. Appetite uncommonly good. 3 p.m., the heat of sacrum spread upwards on 1. side to scapula. Urgent call to stool but without result. 5 p.m., confused head. At I a.m. call to stool, and insufficient evacuation. Sleep restless with many dreams.-9th , 6 a.m., difficulty of waking. After rising, distension and tense feeling of abdomen, increased by touching ; walking caused painful tension and squeezing in every muscle of abdomen, cough caused great pain ; head confused, heavy, and painful in occiput ; warmth in sacrum and weariness. 9 a.m. , while walking fatigue in muscles ofboth shoulders and upper arms, later of all muscles of chest ; disagreeable bruised and tired feeling of body, as after prolonged gymnastic exercises. All these symptoms, together with repeated call to stool, only once with result, lasted till I p.m. While lying in bed pulsation in l. temple. Sleep restless, vivid dreams and sweat.-Ioth. Difficulty of waking at 8 a.m. Very lazy ; head full, heavy, hanging down, weariness . 9.15a.m., 5 dr. In 5 m. oppression of stomach, eructation, nausea. 9.30 a.m., confusion and vertigo. 9.45 a.m., sudden heat radiating from within outwards in head, face, and ears, the latter burning hot. Jo a.m., head very heavy, swaying, stupefied, hanging forwards ; vision indistinct, gait staggering ; burning in sacrum, spreading up to r. shoulder, violent call to stool . 11.30 a.m. , sudden rush of blood to face, dark redness of cheeks with yellowish tinge, also seen in white of eyes ; fatigued appearance, trembling weakness of body, speech very low, pulse soft, small, quick = 96. This lated till 3.30, when profuse sweat broke out, with relief. Appetite much increased. After dinner, urgent call to stool, a copious liquid stool with burning in anus ; this went off in th. 5 p.m., ran about the streets with great agility and speed, without being able to find a resting-place either there or at home. After this had lasted 2 h. he felt as though all feeling had left him, and his mental power was gone, and he could not think. 9 p.m., great prostration and painful fatigue ; shooting, throbbing pain in head, from within outwards, as if it would burst ; feet feel like lead, walking difficult, could not read or write on account of the noise and throbbing in head, especially forehead. Midnight, in bed the roaring and digging in head and vertigo were increased, so that he had to get out of bed and seek relief at the open window. 3 a.m., perspiration came on and relieved these symptoms. Sleep disturbed by anxious, frightful dreams and tossing about, so that his head came to be where his feet were ; he woke often with difficulty of moving and dry heat. IIth, 6 a.m., prostration and laziness, sensitiveness of r. spermatic cord and retraction of r, testicle ; yellow colour of face and sclerotic ; great swelling of

thyroid gland ; head heavy, stupefied, on raising or turning it vertigo. 9 a.m., when walking the former symptoms in sacrum, loins, shoulders, and upper arms, only worse, and persisting on 1. side. This state, to which was added frequent urging to stool, was relieved at 3 p.m. by perspiration . Appetite very great. 6 p.m., all the former symptoms recurred with increased violence and lasted till 2 a.m. No stool in spite of frequent calls. Stupefied sleep disturbed by tossing about and dry heat.- 12th, 7.30 a.m., very tired on rising. Testicles hanging down, heavy, painful. Yellow colour continues. Head as bad as before, but could get through his mental work; must hold head bent forwards and downwards. 9 a.m., on going out the pain in sacrum, loins, shoulders and upper arms became shooting, contractive, alternately with burning and drawing pain, referred to the bellies of the muscles ; this, with frequent calls to stool and increased pain in testicles and spermatic cords, lasted till 4 p.m., and was relieved by profuse sweat. Gait unsteady ; appetite uncommonly good. 7 p.m., to the muscular pains were added transient shooting in 1. hypochondrium, and adull tensive feeling over 1. side of chest. 10 p.m., the last-named symptoms became aggravated to cramp pain ; the shooting pain localised itself in spleen, with a dull, tensive feeling in fundus of stomach, increased by pressure. Soon after this the heart was affected by violent squeezing and shooting, sometimes in base, at other times in apex. These symptoms lasted till 2 a.m., when he fell asleep from exhaustion. Night's rest disturbed.- 13th . Same symptoms as yesterday with marked weakness of memory.- 14th, 8 a.m., laziness, heaviness of lowerextremities, extreme pain in testicles and spermatic cords. Urine passed slowly and in thin stream . Same symptoms as yesterday till 5 p.m., and in addition great irascibility, crossness, dislike to everyone ; he shuns all society, but dreads to be alone ; dislike to speak, despondency, tædium vitæ, constant thoughts of death, fear of, and yet longing for the repose of death. Then anxiety, lachrymose humour, longing for home and his family, at length copious weeping and violent trembling of the body for 1 h., complete prostration. Sleep with the most horrible dreams, frequently disturbed in order to urinate, which left slight burning in urethra.-15th. Excessive weariness and prostration on rising, ill feeling and unhealthy yellow complexion. Urine passed with difficulty, return ofthe head symptoms and the pain in sacrum, loins, shoulders, upper arms, and chest. Appetite increased in proportion to the feeling of illness. 7 p.m., flying, shooting, and jerking contractive cramp pain in l. intercostal muscles ; recurrence of the symptoms in heart, spleen, and stomach in increased intensity, and also in l. kidney. Memory very weak. These symptoms lasted till 2 a.m. Sleep deep, undisturbed, full of dreams.-16th, 7 a.m., difficulty of waking, great heaviness of lower extremities, both legs felt larger. On inner side of r. leg near inner angle of tibia, three soft lumps the size of walnuts, dark red, painless, the upper one seemed to fluctuate in its centre. In other respects the same symptoms as yesterday, relieved by sweat, but after that coming on again.-17th. The same symptoms but slighter, transient stitches in urethra and dull, tensive pain in prostate, frequently recurring during d. Frequent urination that always

left a prickling burning in orifice of urethra. E., tired feeling and burning tensive pains in back of thigh ; legs heavy and painful, gait staggering. Then the nape became affected, causing head to be held in opposite direction for some d. Frequent urination at n.- 18th, 7 a.m., rose with difficulty, legs very heavy. L. leg visibly swollen with a painless swelling, the size of a pigeon's egg, like those on r. leg ; visible swelling of the veins of both calves. Urine passed slowly and in thin stream, leaving a burning along urethra, and tickling pricking in its orifice. Urine turbid, milky, dark, with many mucous flakes, and thick frothy layer on top. Head must be held back ; the slightest movement ofit caused violent vertigo. Memory very feeble. Allthe former symptoms in back and arms. When walking the 1. testicle became painful, enlarged, and hanging down. The r. intercostal muscles and those of the anterior surfaces of the thigh became affected. -19th. Extraordinary sopor in m. 10.30 a.m., dull pains in both knees, they felt heavy, as if gone to sleep, hindering walking for 2 h. , ending with sweat in knees. II a.m. , urgent call to stool, burning in front part of urethra for h., then urging to urinate with smarting tickling in orifice of urethra. After urinating, itching tickling for some m. forth. The headache which began in the m. increased by 2 p.m. to such a degree, especially in occiput, that it caused nausea and violent vertigo which ended in profuse sweat in head, with cold face and body. Appetite unnaturally great. 5 p.m., the head and muscle symptoms returned. 7.30p.m., after a cup of coffee all the symptoms returned with violence and were relieved by profuse general sweat. 9.30 p.m., vertigo while walking in open air, gait staggering. Sleep disturbed by frightful dreams.-20th. No remission of the above symptoms. During d. long-continued erections with disinclination for coitus. To-day only the gluteal muscles were affected, and there was hardness of hearing.-21st. All the symptoms remained, and in addition a very tiresome cough; respiration sometimes much accelerated, sometimes very slow, chest tight,pains in both lungs ; frequent, rough, barking cough causing continued burning in all inner surface of sternum and a painful shooting in both lungs. 9 p.m., slight shooting pain in r. arch of palate hindering movements of tongue , slight discharge of mucus from urethra. N. disturbed by urging to urinate, dryness and pain in mouth.-22nd. Same symptoms persisted ; the painful spot in r. arch of palate had an ulcer on it ; in r. border of tongue two deep transverse fissures very painful. -23rd. The fissures in tongue were changed into sores with hard borders ofan elongated round shape, and in middle of tongue were more deep and superficial fissures which on the 24th were changed into gaping sores causing the most acute pain, preventing him taking anything cold or warm into the mouth or moving tongue. The other symptoms were moderated.-25th. The severe pains in the tongue abated ; small vesicles appeared on its upper surface and borders, and small wart-like elevations on its under surface, and two similar large elevations on each side of frenulum linguæ, which was not painful. Still discharge from urethra, otherwise no troublesome symptom. After this the symptoms all declined and were all gone by the 28th. ( Ibid. , 393.)

1. J. P. HUBER, surgeon, æt. 27, took various dilutions for 48 d. and mother tinct. up to 10 dr. daily for 20 d. without any effect.- Jan. 26th. 10 dr. 1 p.m., lost his breath 3 times when going up a little hill quite slowly, chest felt very hot, and he had some frothy expectoration. Each attack lasted a few m., and in h. felt all right.-27th . 10 dr. , II a.m., 2 similar attacks of breathlessness when walking on a flat road. They lasted at most 3 or 4 m. Next n . very restless, he could not sleep though he felt very sleepy, tossed about till midnight. He took no more medicine, but the restlessness continued for several successive n. (Ibid. , 290.) 8. W. HUBER, surgeon, æt. 26, took various dilutions down to Ist without any remarkable effect.-March 2nd, II p.m., 20 dr. mother tinct. Sour taste on tip of tongue for 2 h.-3rd, 8 a.m., 30 dr. Twitching of muscles of r. upper arm lasting a few seconds and returning after 3 m. 11 p.m., 40 dr., restless and frequent sudden waking on account of frightful dreams, with the sensation as if the bed and floor swayed.-4th, 8 a.m., 50 dr. ; 2 p.m., 70 dr. ; 9 p.m., 80 dr.; forenoon, roughness in throat, deep voice, constant spitting of watery saliva ; afternoon, for 2 h. rumbling in belly.-5th, m., 80 dr.; e., 90 dr., no effect.- 6th, m ., 100 dr.; noon 100 dr.; 11 p.m., 100 dr. M. roughness in throat as from catarrh. 4 p.m., while in warm bath burning shooting and sore feeling in frenum preputii and orifice of urethra lasting 3 h., also violent burning when urinating.- 7th, m., 150 dr.; 4 p.m. , jerking shooting pain in l. upper row of teeth, tobacco not relished ; e., some pricking in belly.-8th, m., confused head as after a debauch, weakness, sleepiness, much yawning, bruised feeling of feet and legs as after great fatigue; some pinching in belly and rumbling for h.-9th, m., 300 dr. Eructation of air, frequent spitting, tongue furred, general weakness and relaxation. (Ibid. , 290.) 9. A woman, æt. 28, well with the exception that she has spasms of uterus and stomach before the menses. May 7th, m., 5 dr. of tinct. Repeated flushes of heat with red cheeks, and feeling as of a veil before eyes.- 8th. 10 dr., burning in both eyes ; pain in forehead which is hot, weight in occiput, weakness, prostration, increased temperature of the whole body, pulse 88, strong and full.-9th. 15 dr., great burning and itching in eyes, pupils contracted, feeling of fulness and weight in sinciput, frontal headache, frequent rising up of heat, heat and fulness of whole body, pricking feeling under skin, which is quite dry, then towards noon moist ; dryness of throat, appetite increased, thirst, troublesome weakness with knuckling of knees under her ; pulse 96, full, tense.- 10th. 15 dr., same symptoms.- 11th. 20 dr.; to the above symptoms there were added heaviness in chest with feeling of tightness there and need to take frequent deep breaths ; slight, deep, transient stitches in lungs, great sensitiveness of both mammæ, hot forehead, cool cheeks, increased flow of urine, pulse 100, strong, full, tense.- 12th. 25 dr., continuance ofabove symptoms, burningin eyes less, sensitiveness of mammæ increased, occasionally flying stitches through them, they felt ulcerated when touched ever so gently, and they felt fuller and heavier. Urine copious, turbid, pulse 112.-13th. 25 dr., forehead felt full of lead, pulse 106. All other symptoms re

mained the same, also a cutting contractive pain in abdomen.-14th . 30 dr., in h. constriction in stomach and soon afterwards in abdomen, which felt hot and tense ; after great straining vomiting of a little watery fluid mingled with streaks of light blood. In forenoon three liquid stools, head very confused, heavy, hot, increased heat of body followed by general coldness of body with hot head. (JENICEK, Ibid. , 365.) 10. Dr. VON KACZKOWSKY.- 26th May, I dr. of mothertinct. No effect.- 27th, 10 p.m., 3 dr. On waking cheerful, pricking as from needles on various parts of body, drawing and stretching in joints, tension in soft palate and secretion of compact mucus. 9 a.m., a glass of liqueur caused heat of whole body and confused head. Noon, great weakness and little appetite.-28th, 12 midnight, 7 dr. Sweat during sleep, quite unusual. On waking weakness, crossness, anxious restlessness as if something bad was about to happen to him, no desire for coffee or cigar. 7.30 a.m., a loose stool with burning in rectum, which recurred frequently during d.; prickling and itching in various parts of body; drawing and stretching in joints. Noon,no appetite, great shivering and weakness. E., weakness, thirst, scanty urine, turbid and smelling peculiarly, sleeplessness.-29th . At midnight 10 dr. M., head confused, inclination to sigh, tightness of chest, sensitiveness of ankles and wrists. 7.30 a.m., loose stool with burning in rectum ; head confused, tension of cervical muscles and glands. -30th, midnight, 10 dr. M. tightness of chest as from mental emotion ; pulse quick, head confused, sometimes vertigo. E., great heat of body, itching in rectum and genitals, urine scanty, turbid, with smell of Russia leather ; no inclination to sleep.- 31st, 11 p.m., 10 dr. M., weak, prostrated, heat in head and chest with deep sighing ; pulse quick, appetite diminished, great drowsiness after eating; after 20 m. rest great weakness, drawing and stretching in limbs, heat in rectum and genitals, urine scanty with smell of Russia leather.-June 3rd, forenoon, I dr. Heat of head and chest, little appetite, unusual thirst ; towards e. weakness, heat in rectum and genitals .-4th, forenoon, 2 dr. On rising stretching and straining of limbs, heat in head and chest, flickering before eyes, qualmishness in stomach with yawning, little appetite, much thirst, great drowsiness after eating ; after 20 m. increased weakness and heat in rectum and genitals. Urine scanty, high coloured, no peculiar smell.-5th , forenoon, 5 dr. N. restless ; single tearings dart through body like electric shocks, sometimes on r., sometimes on 1. side. On rising heaviness of head and chest with deep breathing ; no appetite for breakfast ; easy stool with hot feeling, then burning in rectum. Pulse quick, qualmishness of stomach with yawning, little appetite for dinner, great thirst. Great drowsiness after dinner ; after 15 m. rest, cross, giddy ; e., tightness of chest.- 6th, forenoon, 10 dr. Long of falling asleep, restless dreams, profuse sweat ; on rising weakness, prostration of limbs, head heavy, tightness of chest, loss of appetite, sadness, ill humour, hot feeling in rectum and genitals, burning and itching in anus after an easy stool, qualmishness of stomach, great drowsiness after eating. After 20 m. rest, head heavy, giddy. E., increased heat with anxiety in chest, no desire to sleep. -9th, forenoon, 10 dr. N. disturbed by disagreeable dreams, sometimes with jerking like electric shocks, weakness, prostra

tion of limbs, heaviness of head, tightness of chest, frequent deep breathing, stool easy, followed by burning and itching in anus, pulse quick, urine scanty, dark coloured, ill-smelling. These symptoms lastea till 12th; by 14th was well.-July 11th, 10 p.m., I dr., no effect.- 12th, 11 p.m., 2 dr. On waking weakness, anorexia, flat taste, disinclination to work, on walking great weariness and slight oppression of chest ; after eating, irresistible sleep for 20 m., thereafter increased laziness. In e. ebullition and sexual excitement.-13th, forenoon, a screwed-up feeling in head as from iron cap, prostration oflimbs, tightness ofchest with deep sighing. Great drowsiness after eating. Midnight, 3 dr. Towards m. copious sweat of peculiar smell, urine high coloured.- 14th. Very weak on rising, could hardly get up. On walking or going upstairs heaviness of limbs, tightness ofchest, pressure on cranial arch and optic nerves. Noon, no appetite ; e., in society attack of weakness followed by perspiration. 9.30 p.m., 4 dr., sleep profound, full of dreams.-15th., m., the same weakness, heavy head, tight chest, deep-coloured urine, smelling of violets, hot ; during a loose stool burning in anus. Feeling ofprickling and itching in scrotum that had occasionally been felt increased to a great degree ; heat when urinating, burning irritating feeling in scrotum ; e., 7 dr.-16th. On waking tongue thickly furred, symptoms same as before. After dinner and siesta much heat of head and chest, frequent sneezing, roughness in throat. E., pain in the cervical glands (that had formerly been swollen). 9 p.m., 10 dr. , sleep restless, full of dreams.-17th. Weaker on rising than when he went to bed, roughness of throat as usual, frequent sneezing, cervical glands (not swollen) more painful, other symptoms as before. E., transient feeling of cold. 9.30p.m., 13 dr.-18th. To usual symptoms are added burning of eyelids, discharge of much flatus, burning in soles, 2 stools, with burning in anus and swelling of a pile, formication in genitals. 10.30 p.m., 15 dr.-19th . After a restless n. all the symptoms in aggravated degree. Somewhat relieved in open air. Some blood with stool. E., 18 dr.-20th. Same symptoms. 11.30 p.m., 20 dr.; after a very restless night, with dreams and sweat, head felt as if screwed in a vice ; after stool great faintness ; other symptoms as usual. No more medicine taken. The confusion of head lasted 3 d., the stomach symptoms 2 d., the sensitiveness of eyelids a fortnight ; the loose daily stool gave place to a hard stool every other d.; the dark-coloured violet-smelling urine became for a few d. like whey, and smelt fetid ; later the stools became again loose and every d. the feeling of weight in sacrum and swelling of pile returned. Some small itching scabs appeared on hairy scalp, a burning hot feeling in soles ; transient stitches in joints ; single itching pricks in forearms, thighs, and about genitals ; when scratched an urticarious efflorescence appeared, which soon went off. (Ibid., 367.) 11. Dr. KLINKOWSKI.- Sept. 6th, 6a.m. 5 dr. tinct. Immediately warm feeling all over body.-7th. 10 dr., same warm feeling and increased activity of mental powers for h., giving place to sulky humour and disinclination to mental work. Increased urinarysecretion. -8th. 15 dr. , same symptoms. These 2 d. 2 loose stools ; his habit was to have a stool only every 3rd d.-9th, at n. woke frequently with a

start, followed by anxiety and sweat, especially on forehead.- 10th. 25 dr., immediately feebleness of thinking faculty with sulky, restless disposition. At same time transient burning stitches in 1. groin ; the glands there were swollen. E., besides the pain in groin, had pressive pain in 1. shoulder-joint, especially on raising arm. N. passed in tossing about in bed, with anxiety and sweat on forehead.- 11th. 25 dr., the stitches in 1. groin more continuous, the glandular swelling increased. The pain in shoulder-joint at first drawing, then tearing, at last spreading all over 1. side of chest as a prickling sensation, felt at all times. E., felt an annihilating sensation of moral weakness, so that for more than h. he wept, and then fell asleep for 3 h.- 12th. As the inguinal gland was greatly swollen, and the pain in shoulder continued, he left off the medicine ; these symptoms grew slighter and were gone in 3. d. , but the loose stools still continued twice a d. for a considerable time. The urinary secretion, from being increased, became scanty. ( Ibid, 371. ) 12. Dr. W. Löw, from Jan. 20th, took daily 2 to 3 dr. of tinct.- 28th. There occurred a most unusual mental state; he felt as if oppressed by some secret grief or vexation about some disagreeable event, and the foreboding of some coming disaster.- 27th. Woke tired, as if he had spent the night in dancing, with oppression of chest and precordium. E., restlessness and oppression ; good appetite ; drowsy. -28th . Woke uncomfortable after a restless n. E., very exhausted.- 29th. Woke by a burning-itching pain in r. cheek and ala nasi. The painful part showed a circumscribed redness covered with small elevations. Towards e. numerous vesicles size of pins' heads appeared on spot and neighbourhood, with painful burning sensation. Little appetite and desire for repose.-30th. The vesicles grown the size of lentils.- 31st. A similar eruption on thigh with heat and itching. In spite of his depressed spirits the sexual desire was increased. (Ibid., 373.) 13. Dr. A. VON MARENZELLER began his provingofthe mother tinct. on June 17th, taking 4 dr. every other d. The symptoms observed were frequent sneezing with transient increase of nasal mucus, nocturnal headache, palpitation ofheart, which occurred froinJune 17thtoJuly 1st. He considered these symptoms as accidental.-From 1st to 5th July he took every d. 8 dr. As the above symptoms reappeared in still greater intensity, he was convinced that they weredue to the drug. The most prominent of the symptoms was the headache, which came on invariably soon after midnight, and woke him up repeatedly. It was a pressive pain in occiput extending to nape, and towards the front ofthe head, like what occurs after taking too much alcohol ; sometimes it was as if the head had been in a bad position, at the same time palpitation of heart which prevented lying on 1. side. During thed.frequent sneezing as if coryza were about to come on, with transient increase of nasal mucus, sometimes cough with expectoration of mucus. These last symptoms lasted about h., then went off and recurred about 6 times during d. The last 2 d. there was unusual weakness, drawing tearing now in 1. now in r. leg down tibia to ankle ; single more violent tearings in r. finger-joints, especially when moved ; frequently tickling in urethra, especially in fossa navicularis, also several pimples on the face, which he had formerly often suffered from, but not fora long time

previously. Appetite was rather increased than diminished. The head symptoms lasted, though in diminishing intensity, for about 6 d. after leaving off drug. (Ibid. , 374.) 14. N. N-, medical student, æt. 25, had had in childhood measles, two attacks of scarlatina, the second time with general dropsy. From Oct. , 1853, to beginning of 1856 had suffered from frequent attacks of indigestion accompanied by intolerable headache especially in 1. temple, great irritability, tendency to melancholy, some feverishness, great weakness, and faint feeling.-August 10th. 4 dr. tinct., eructation for several minutes and tensive sensation in stomach.- 11th. 6 dr., same symptoms but more severe.- 12th. 8 dr., the eructation continued longer, with pressure in stomach and tension ofwhole abdomen, going off in forenoon ; he was excited, cheerful ; less sleep than usual, vivid dreams ; stools hard, scanty.- 13th . 10 dr., no eructation, slight tension of stomach, excitement continued. 10 p.m. , disagreeable prickling sensation in r. inguinal glands for 10 m. Sleep uneasy. 14th, 12 dr.; except excitement, none of the other symptoms. E., great pain in r. inguinal glands and transient pain in r. axilla, restless sleep.- 15th. No med. M., remarkable swelling of both inguinal glands, which are painful on walking, great headache, weakness, prostration, furred tongue ; depressed spirits and drowsiness.-16th . No med. R. inguinal gland more swollen, pain in it prickling but not lasting long, increased when walking or when in bed, great prostration, diminished appetite ; no stool ; 1. inguinal gland a little swollen.- 17th . 14 dr. , swelling of r. inguinal gland was in e. more conspicuous both to sight and touch ; no pain,only tensive feeling when walking. The drowsiness and weakness continued, but appetite returned.- 18th . No med. Same symptoms.-19th. 16 dr., during d. frequent eructation, distension of stomach and and abdomen, swelling of r. inguinal gland very conspicuous, pain only when walking.-20th. R. gland still swollen, 1. still a little ; considerable headache, no stool, diminished appetite, weakness, drowsiness.-21st. Felt unwell. Same symptoms. -22nd. Gastric symptoms and headache better after stool ; inguinal glands as before.-23rd. Inguinal glands unaltered, otherwise better. -24th. Inguinal glands the same, some tension in them when walking. -25th. 18 dr.-26th. 20 dr.; no increase of glandular swelling. The glandular swelling continued unaltered for 4 d. longer ; it then began to decline and was gone on the 10th d.,but the tensive feeling in that part lasted other 2 d. (Ibid., 376.) 15. Dr. JOSEPH RAIDL, æt. 47, in good health, on May 7th, 5 a.m., took 5 dr. mother tinct ; no effect. 8th, 5 a.m., 10 dr. No effect.- 9th, 5 a.m., 20 dr. Afternoon, slight sensitiveness of hairy scalp, on a spot the size of half-a-crown on r. side, also slight itching in inner canthus of r. eye.-10th., 6 a.m., 30 dr. The sensitiveness of scalp extended over whole front ofhead, and was more intense, the itching and burning in r. canthus increased and extended to 1. inner canthus.- 11th. 30 dr., same symptoms, and in addition drawing pain on r. side of forearm from elbow downwards, combined with difficulty of moving it. Felt very sad, no inclination to speak ; sleep restless at n. -12th, m., felt very exhausted, the sensitiveness of scalp continued ;

there were yellow crusts in inner canthus. 5 a.m., 40 dr. ; in addition to the former symptoms, violent itching in hairy scalp, the epidermis there came away in bran-like scabs ; as if a veil before eyes, the letters disappeared on reading, sometimes quite dark before eyes ; great prostration, little appetite, very sad. At n. little sleep, dreams of unfortunate occurrences.- 13th , m., all the former symptoms, but spirits better. Afternoon, stitches at base of glans penis, itching in fossa navicularis, frequent call to urinate and erections of penis.- 14th . Spirits good, still itching of scalp, in canthi, in glans penis, and fossa navicularis, scaling of epidermis continued.-15th, m., 30 dr. No new symptoms, nor yet on the 16th, when he took 30 dr., only the itching ofscalp and scaling of epidermis were observed.- 19th. Four inflamed cutaneous glands in 1. thigh. During the next 14 d. several more such inflamed glands appeared in different parts. They appeared as deep-red pimples the size of millet seeds, with a red areola ; many of them gradually disappeared, others became filled with thin pus. From 20th to 24th, every morning 20 dr. of Ist dil., which caused no symptoms.- 24th . Felt in both groins a disagreeable tension, and the glands were swollen.-25th. 20 dr. Ist dil, during d. slight stitches in fossa navicularis, inguinal glands continued swollen, and also on 26th. -27th. Noticed on his shirt three small spots made by discharge from urethra. After standing for 2 h., chiefly on 1. foot, felt more tension in 1. inguinal region, and the following e. increased swelling of 1. inguinal gland. During next 4 d. the swellings began to diminish so that on June 2nd only the l. gland remained slightly swollen ; after 2 d. no more urethral discharge, but the inflamed cutaneous glands were still there, and the cutaneous nerves were very sensitive to cold and the friction of the clothes. No more medicine was taken during June.-3rd. About 3 p.m. such exhaustion and weakness he had to go to bed. Then there came on heat, headache, great thirst, pulse 100, urinary secretion very scanty and dark coloured ; n. very restless.-4th, m. , felt better, and could get through his work, though with difficulty. After dinner great weakness, heat, &c., as before. So it went on till 8th, when after profuse sweat the previous n. and much chloride found in urine, he felt much relieved.-9th. Very weak. At n. very restless, recurrence of the heat, headache, thirst, and all the former symptoms with increased intensity, so that on 11th and 12th he was delirious during the e. exacerbations. From this time till 24th felt as if the skull were too small for the brain ; the sensitiveness of scalp returned, and also the scaling of the epidermis. Inflamed cutaneous glands appeared on face, and upper and lower extremities, which often went on to suppuration. During these days he had great thirst, suppressed cutaneous secretion, rare stools, the sp. gr. of the urine ranged between 1024 and 1026, the pulse between 90 or 100. Great weakness, restless sleep, perceptible emaciation, especially of lower extremities. The n. of 24th, he had copious sour-smelling sweat, the urine was in greater quantity and contained much chloride. Began to mend on 25th, and by 28th was quite well. (Ibid., 378. ) 16. Dr. REIS. Is a very nervous man, subject to congestions of head, vertigo, permanent tinnitus of r. ear, slight illusions of vision, and

hæmorrhoids.-May 19th. 5 dr. II a.m., objects appeared to r. eye indistinct, enveloped in colourless mist, forth. (a not uncommon symptom). Noon, some frontal headache, relieved by pressure, aggravated by cold ; empty eructation, inclination to vomit, much saliva, complete anorexia, feelingofdiscomfort, weakness ofwhole body, gloomy disposition, bitter taste, head confused.-20th. Woke with slight confusion of head, bitter taste, tinnitus of r. ear greater than usual.- 21st. 5 dr., no effect.-23rd. 15 dr., only the above-mentioned eructation.-24th. 30 dr., slight burning in cœsophagus, eructation. E. , the same affection of the sight as that observed on the 19th, forth. in the l. eye. (Ibid., 382.) 17. Dr. IGNAZ SCHÜCK, æt. 41.-July 9th, 6 a.m., 10 dr. tinct. No effect. 7 p.m., 20 dr. After 24 h. burning and itching on back and chest, especially sternal region, and transient flushes of heat along whole back and chest. After walking for h. in open air, extreme weariness and exhaustion, with dull frontal headache and itching of fore part of hairy scalp. Must go to bed earlier than usual, but did not fall asleep before tossing about restlessly for a long time, with increased heat and constant headache ; sleep disturbed by confused dreams. Woke at 3 a.m. with a sudden start, and could not again fall asleep.-roth, m., felt quite dazed and bruised ; temperature of body cansiderably higher, pulse 90, full and irregular, occasional shooting and drawing pain in r. hip-joint and whole hip extending forwards to groin, r. inguinal gland somewhat swollen and painful when touched, shooting tearing pains in inner side of r. ankle. No appetite for breakfast. By noon the swelling of inguinal gland was somewhat abated; troublesome disposition to erections . Urine dark-red, saturated, no sediment. Two diarrheic stools in forenoon. 2 p.m. , great appetite. After dinner uncomfortable pressive tensive pain in forehead and temples, occasional stitch-pain in hepatic region, especially when moving. Sleep restless and dreamful.- 11th, 6 a.m., 30 dr. The first h. had only slight frontal pain and occasional stitches in inguinal region . 10 a.m., the frontal headache increased to an intolerabledegree, combined with tension and pressing in temples, and tearing and drawing in nape ; the burning and itching on back and chest returned with greater intensity ; pulse 95 ; mouth and tongue quite dry, thirst and longing for ice, which did not refresh, violent shooting and throbbing in two carious teeth, feeling as if uvula were too long, occasional dry cough, painfulness in hypogastrium extending to penis, increased sensitiveness of both inguinal regions, though the swelling of r. inguinal gland was almost gone ; tearing-drawing pains in r. arm and knee, also in both ankle-joints and r. big toe ; alternate pain in liver and spleen only coming on during certain movements, and soon going off; complete anorexia, general exhaustion and prostration, 3 diarrhoeic stools, urine scanty, with burning pain in orifice of urethra as the last drops flowed. 9 p.m., irresistible desire to sleep, but on going to bed could not go to sleep till 11 p.m. Woke once at n. with a vivid dream . -12th. Continued frontal and temporal headache, dazed feeling as after a n. spent in dissipation, itching in fore part of hairy scalp, occasional tearing and drawing in nape,where there are some itching vesicles, disagreeable pasty taste not removed by breakfast, still some sensitiveness

of uvula, frequent irritation to cough with some mucous expectoration, itching on chest, back and outer side of thighs, slight swelling and painfulness of r. inguinal gland, tearing and shooting in r. hip-joint, knee- and ankle-joint, violent pain in r. heel which soon goes off, but returns for a short time in afternoon. The other pains much mitigated. No stool.- 13th. Still some exhaustion and prostration in m.; otherwise well. (Ibid., 383.) 18. Dr. C. WALTER.-May 8th, 6 a.m., 5 dr. tinct. Soon, cold feeling in mouth, increased by drawing in air, taste like decoction of salep.-9th , 6 a.m., 10 dr. earlier, before taking drug, a quantity of flatus discharged smelling of old cheese (he had eaten some previous e.). Cold feeling in mouth and salep taste continues. M. and afternoon, copious loose stool. Tension in 1. inguinal region, extending down into thigh and increased by walking. Afternoon, increased thirst.- 10th, 6 a.m., 15 dr. Cold feeling in mouth and salep taste less; tension in groin continues. During d. several stitches in hepatic and splenic regions. E., frequent shivering and fits of heat and cold, violent pain in head as if it would burst, forehead and cheeks hot, the latter red ; burning in eyes as if fire streamed out of them, and dry feeling ; appetite diminished, with thirst, tongue furred white, hands dry, hot, and felt swollen ; arms, sacrum, and thighs felt bruised ; pulse not accelerated, 73 ; scanty and lumpy stool in e.- 11th, 7 a.m. 20 dr. Tension in groin diminished, burning and dry feeling in eyes, dry, rough, and astringent feeling in tongue, bruised feeling in both renal regions, glutæi muscles and thighs, when touched and on moving, especially stooping ; two loose stools.- 12th, 6 a.m., 10 dr. Soon, slight pressure in stomach, yesterday's symptoms continue ; three loose stools.- 13th. No med. Great prostration and weakness all over, head confused, forehead hot ; burning heat and dryness of eyes, which are red and sparkling ; nose hot, with thin discharge ; frequent sneezing ; tongue white, gums and teeth sensitive when chewing ; thirst ; transient stitches in both hypochondria, tension in glands of 1. groin, pains in 1. external and internal inguinal rings ; bruised pain in sacrum, kidneys, and thighs ; rheumatic pains on outer side of 1. knee and hough for some h., interfering with walking ; transient tensive shooting pains in r. outer ankle ; two loose stools.- 14th . Woke up at 3 a.m. with burning heat in feet and hands. Rose at 4 a.m. on account of restlessness and dry heat, took 30 dr., and went out walking at 4.30 a.m. Head giddy and full as after a night of dissipation; eyes burning hot and dry, making him close lids ; the nasal mucus streaked with blood ; tongue white, taste pappy and astringent ; pressure in stomach, tension and shooting in hypochondria, causing difficult breathing ; tension and pain in inguinal glands and rings ; feeling as ifscrotum were retracted, as from cold, which was not the case ; the above-described pains in sacrum, kidneys, and thighs, stiffness in 1. knee-joint, tensive shooting pain in both elbows and wrists, hands and feet dry, hot, and former as if swelled ; urine hot ; two loose stools.-15th. No med. , former symptoms continue ; m., cough with little expectoration, occasional cramp in calves. Afternoon, violent cutting in hypogastrium, followed byVOL . diarrhea II . ; e., violent pain in head, as though it would burst. 17- 16th .

No med. Extraordinary bruised feeling and weakness, head confused, eyes burning and dry, astringent taste; feeling as if toothache would come in last r. upper molar, which is carious ; under point of r. scapula for some h. flying stitches, making inspiration difficult ; stitches in liver and spleen ; less tension in inguinal region ; rheumatic pains in knee-, ankle-, elbow-, and wrist-joints ; hands feel swelled, dry, and hot; two stools, a quantity of urate of soda in urine.- 17th, 6 a.m., 40 dr. Soon inclination to vomit, for I h. All yesterday's symptoms continue.- 18th, 6 a.m., 50 dr. Inclination to vomit all forenoon ; bruised feeling less, head freer, taste better; the rheumatic pains continue, and are also in metacarpus and fingers ; three stools .- 2 Ist. Began a fresh proving with 50 dr., increased the dose at intervals of a few d. to 60, 70, and 90 dr. During this time he felt extraordinary tired feeling and bruised sensation in all limbs, especially on waking in m.; this went off by walking in open air. Itching in various parts of skin, especially the hairy parts, making him scratch; frequent yawning ; shivering especially on back ; very cross and unhappy, no inclination to speak ; plunged in thought without knowing what he was thinking about ; great confusion of head, with pressure and tension in forehead ; burning and dryness of eyes ; burning pain in both external ears, with heat perceptible to touch ; some coryza and frequent sneezing, dull toothache in hollow tooth for a short time ; some pain in gums, worse on chewing; tongue on waking dry and rough ; no appetite, soon satiated ; nausea when smoking ; frequent flying stitches in liver and spleen ; liver painful, increased by pressure ; pressure and tension in sacrum and kidneys, increased by stooping, which was often impossible; feeling in inguinal ring and glands as if a swelling would come there ; stools loose and more frequent ; scrotum often retracted ; occasional stitches in chest, worse during inspiration ; on outer side of 1. elbow pain as if he had got a blow there, increased by pressure and movement. ( Ibid., 386.) 19. A woman who took 3ss. of tinct. at once had very depressed spirits and thoughts of suicide, with feeling of illness, nausea, and violent shooting in palms and soles. (Ibid. , 391.) 20. Dr. K. WüNTT, æt. 28, took on successive days 5, 10, and 20 dr. without any effect.-May 18th. 25 dr., after some h. disagreeable cold feeling in stomach, nausea, confused head, and vertigo.- 19th. 25 dr., in addition to above symptoms he observed when writing that the letters appeared to run together ; sometimes there was diplopia and flashing before eyes ; confusion of head increased. During d. frequent sneezing, stuffed nose, tickling in larynx, and cough ; eyes red, pulse 80. N. restless, tiresome dreams, frequent waking and starting out of sleep.- 20th and 21st. 30 dr. each day ; stools, hitherto always easy, became rarer and harder. The catarrhal symptoms continued these 2 d.; congestion of head ; great prostration and drowsiness, aphthæ in mouth, swelling of submaxillary gland.-22nd and 23rd. Each d. 35 dr., same symptoms, headache limited to forehead, pressive.- 25th. 40 dr., after I h. drawing downwards in lower extremities to soles, lasting h.; disagreeable pressure in both testicles.-28th and 29th. Each d. 45 dr., no effect.-31st and June ist. Daily, 50 dr., no effect.-7th and 8th .

Each d. 40 dr. Ist dil. Head somewhat confused, weakness and prostration, restless sleep.- 11th and 12th. 60 dr., drawing in various parts of body, especially feet ; no stool these 2 d.; on the last headache all over head, with noises in ears. (Ibid., 391.) 21. a. LEMBKE.- Feb. 26th, 1853, 7 a.m., fasting, gtt. v. oftinct. Tearing in bones of head, 8 o'clock. Strong pressure and boring r. elbow-joint and above and below it, 8.45. No other symptoms. 28th, 7 a.m. , gtt. v. Boring above r. elbow, 7.45. Wandering pain, like pressure, in legs, bones of head, r. shoulder-blade, in front r. shoulderjoint, toes, knees, 1. maxillary bone, and tarsal bones. These pains last to9.15 and appear stronger while sitting than walking. Several fugitive stitches in bladder, 8 o'clock. Frequent urging to urinate, 9 o'clock . March 3rd, at 6.45 a.m., gtt. xv. After h., tearings in l. forearm ; disgust ; tearing in frontal bone. Pressure in l. leg. Heavy feeling of exhaustion in legs and back even from moderate moving indoors. Tearing pain in abdomen, especially umbilical region ; aggravated from pressure ; lasting h. Urging to urinate, 7.30. Pressure in r. forearm , 1. toes,here and there inbones ofhead. Stitches in urethra. Drawing in teeth , nasal bones, sacrum, toes, shins, fugitive and not always equally strong, 8 o'clock. Tearing pain from lumbar vertebræ going round lower part to front of chest. Heaviness r. arm with pressing through it. Pressure in ankle-joints and tarsal bones. After 9.15, no further symptoms. 8 p.m., while sitting, suddenly a sharp stitching pain below 1. ribs during which breath involuntarily stopped, body inclined to the 1. and hand pressed deeply into the spot, lasted I m. Alld., especially first hours after medicine, very marked, unusual accumulation of flatus in abdomen. 8th, at 7 a.m., gtt. xv. Same symptoms as 3rd, ceased 9.15. Pain in 1. side did not occur, but stitches in whole r. half of chest at 7, stronger from breathing, without any cough, lasting I m. 9th. -During stormy cold weather, tearing in r. arm and 1. ankle-joint. At occiput below skin a painful nodule, size of peppercorn, never occurred before. Dispersed by 11th. 21st, 6.45 a.m., gtt. xxv. 7 a.m., beginning of pains injoints, boring and pressing, with feeling of exhaustion. Pressure in forehead and vertex. Tearing in bones of leg, 1. elbow-joint. Lasting sharp stitches in r. thumb-joint (?). Strong boring in ankles. Tearing in bones of head, especially in frontal and parietal bones, 8 o'clock. Pain in limbs between 8-10 o'clock, but slight. Headache lasted through greater part of day. 9.30 p.m., strong lasting boring in l. ankle-joint while sitting. Sudden sharp stitch I. side under ribs, 10 p.m. April 17th, 7 o'clock, gtt. xl. Until 10.30, no symptoms. Then violent pain in 1. halfofchest above, worse at each inspiration ; when breathing deeply pain penetrated through 1. breast to shoulder-blade, deep respiration being impossible, and causing involuntary calling out. No cough ; external pressure had no effect. Moving 1. arm backwards or straight upwards aggravated pain to utmost and could not be borne. Pressing 1. scapula against back of chair or inclining body to 1. side considerably aggravated the pain. Only when sitting quietly and breathing superficially I hardly noticed the pain. Walking in the open aggravated itmuch. Never had such thing before. Before taking medicine at 7 a.m., I had without cause attack of hiccup, which

I used to get formerly for a few minutes, but had not had it for some months, The med. had no influence on it, and it ceased only at 8.30, after food ; but I had a hiccup every or h. during whole day. At 9 p.m. it began again with same violence as in m., much aggravating the pain in chest. Hiccup lasted for more than I h. and ceased only after forced in- and ex-piring in quick succession. At n., pain in chest woke me several times. Lying on r. side not tolerable. 18th.-Pain almost as violent as previous d. in m. Deep respiration remained impossible, violent boring pain in 1. shin-bone before and after rising, and repeatedly returning. 20th.-Pain in chest not quite ceased. 25th, 7 a.m., gtt. l. Immediately after med., pain in calves, arms as if beaten. Heaviness of head. Pressure at different spots of cranial bones. Sickness . Pressive pain in different joints, making movements very difficult. Several times cutting belly-ache, 10 o'clock. 28th, 7 a.m., 100 dr. Pressive pain in wrists and ankles, 7.30. Head heavy. Pressing in different spots of it. Feeling of exhaustion in whole body as after great fatigue with stiffness ofjoints and frequent cracking during movements. Dull pressure in orbits when moving eyes, pressive pain between shoulder- blades and in lower part of thorax, 8 o'clock. Pain with inspiration in upper part of 1. chest. Strong pressure in ankle-joints, toes, knees, shoulders, elbows, upper arms, feeling as if these parts were turned and pulled asunder. Dull pressure in bones of head. All these symptoms last till about 3 o'clock . b. May 6th, at 6.45 a.m., 150 dr. Immediately after med. pains begin in joints and bones of head, frequently shifting. Strong drawing in bones of legs. Pressure in sacrum and higher up often repeated. Boring in bones of r. head, 9.30. Painful exhausted feeling in legs. About mid-day, no symptoms. In e., stitches orifice ofurethra. 7th.- Violent boring in bones of r. head and pains in joints. (Z. f. h. Kl., ii, 14.) 22. HENCKE.-July 13th, 1844, at 9 a.m., took gtt. xx of tinct. within 1 h. in glass of water ; on 14th, gtt. xxx. 15th.-Awoke with fugitive tearing pains on r. patella, which remained fixed soon after rising in r. leg, especially shin-bone, for several h. During following day, frequent, sudden, but short-lasting, tearing pains now in 1. now in r. half of head. Slight pressive pain in region of stomach after very moderate dinner. In e., urging pain in urethra, not urinating, when standing, decreasing when sitting, and disappearing lying in bed at n. 16th, 17th, and 18th.-Troublesome, pressive pains lasting in r. shinbone, especially painful when walking ; when driving, always pain in r. knee supervened. Several times, especially in e., tenesmus in urethra. During n. sleep restless, disturbed by voluptuous dreams. After 19th symptoms gradually disappeared. On 25th, gtt. xl ; 26th, gtt. l. Soon after last dose, furious pressing pain in temples. During day similar pains on shins and troublesome pinching (urging pressing) pains in testicles, which pained after slight touch, but were not swollen. All these symptoms aggravated from walking. After dinner again pressive pain in stomach, later fulness and tension in abdomen, stool regular. On urinating, some burning in urethra, which was tender to touch. 26th.-Restless sleep at n. During d. heaviness in all limbs. Head

confused, sometimes painful, especially in temples. Digging pains in shins, also in ball of r. big toe. Pressure at stomach after dinner, fulness of abdomen afternoon. At times digging, pressing, urging pains first in r., later also in 1. testicle, but lasting only for a m. each time. Burning in urethra during micturition. Unwonted sexual excitement. Symptoms disappeared by 30th. 31st.-Gtt. lx. Besides symptoms as above, which lasted for a few days, easy perspiration and copious thin stool on Aug. 5th. After this well. (A. h. Z., lxvii, 201. ) 23. Mrs. N-, no family, æt. 36, formerly cook, of violent temper, dark complexion, years ago suffering from rheumatism, since some years very well, took with me, in same way, July 13th, gtt. xx oftinct.; on 14th, gtt. xxx ; on 15th, gtt. xl. Complained in e. of recurring tearing pain, but not lasting long, in 1. upper arm. 16th.-Also tearing in 1. hip, sacral pain ; disappeared after 3 d. 25th.-Gtt. xl ; 26th,gtt. 1 ; 27th, gtt. lx ; 28th, gtt. lxx. 29th.-Sleep restless, dreams ; during d. digging, pressing pains in sides of head, extending to occiput, and similar pains in l. upper arm, worst in shoulder, much impeding movement of arm. In e. moderate pain in r. molars, which were sound, of similar character as the pain in head and arm. Biting, burning pains in eyes. Conjunctiva bulbi slightly reddened. 30th.- Sleep restless, disturbed by dreams. In m., r. cheek much swollen and tender, yet no more toothache, but pain in arm from shoulder extending to elbow. No other change. 31st.-Restless sleep, dreams, had to get up to void urine several times, which was quite unknown to her. R. cheek still much swollen, tip of nose red and swollen. At root of nose small, tender, red nodule. Pain in the upper arm and shoulder still continue. Frequent desire to urinate with scanty discharge. Urine clear, reddish ; during micturition disagreeable pressure in genitals, which often troubles without micturition. Aug. 2nd.-Swelling of cheek has subsided, other symptoms less or disappeared by Aug. 6th. Menses more profuse than usual. (Ibid.) III. Experiments on animals.-1 . An oz. of powdered leaves was given to a small dog. It slept for over an h. and then had diarrhœic stool and very abundant diuresis. (STOERCK, Lib. de Flamm. Jovis, 1769.)