Mercurius bromatus
от Richard Hughes & Jabez P. Dake — A Cyclopaedia of Drug Pathogenesy
Volume IV — Appendix
MERCURIUS BROMATUS.
I. Prtvingt. — I. Dr. Werneck took i to ^ gr., which caused slight wssure and pain in bowels, i gr. caused increased secretion of urine, >Hcky pains, and several loose stools. i| gr. caused nausea, retching, icreased urine, and after \ h. violent painful vomiting, increased
cutaneous secretion, salivation ; it also affected stomach and digestion. 4 to 6 grs. caused 4 or 5 loose stools. (Grafe und W althul, Jturt, f. Chirurgie und JugenheUiunde^ xiv, 2, p. 216 — 22g. 1830.)
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HoRiNc took J er. ; this caused very disagreeable sensation ia gullet, slight pinching in belly. After ^ gr. these symptoms were aggravated, also pressure in stomach -, after j h. 2 loose stools, increased salivary secretion. After i gr. disgusting taste, rough, scrapy fcclitij in fauces causing cough. After I h. pressure in stomach, 4 watery stools. He had the most violent pain in abdomen and painful tenesmus ; hegotquite weak, pulse slow and small. He vomited twice during pain in abdomen, with great effort. The abdomen was drawn back towards spine, very painful to touch, increased secretion of saliva and urine. During the pain the body was covered with perspiration, owing to the great anxiety. Several weeks after this trial he was troubled with many boils on different parts of body, especially in I. axilla and arm. As fast as one boil healed several others appeared ; he could ge no rest day or night. He went to Wild bad, took the baths and drank the waters, and was not well till after 3 weeks. {If^iriungin dt Brums, 1838.)
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Heiemrdikoer took ^ gr., which caused nasty metallic tun increased saliva, burning pains in throat and stomach, eructation, violent retching, obstinate vomiting of viscid, later bloody mucus ; some dy$ea teric stools, often only of viscid bloody mucus, with violent tenesmus oppression of breathing ; sometimes trembling of body or limbs ; pull quick, small ; anorexia, thirst, great dejection, belly retracted, un increased, (inaug. Diss,, Tubing., 1838.)
III. Experiments on animals. — i. In animals death occurred eithl quickly with convulsions, or slowly with emaciation. P.M. showi m. m. of stomach greatly inflamed (after large doses), extravasation blood in its tissues, which were sometimes emphysematous. The m. m of remainder of intestinal canal, especially the rectum, inflamed various places, the lungs collapsed, dirty red, of doughy feeli (Heiemrdinger, I.e.)