Indigo tinctoria

Volume II — Main text

INDIGO .

Adye prepared from leaves and stems of Indigofera, L. Nat. Ord., Leguminosa. I. Provings.-1 . BLAUFUSS took, Dec. 11th, 8 a.m., 1 gr. After 1 h., great urging to urinate as many as 4 or 5 times in the h. Spasm in parotid gland, much saliva, pressure and noise in ears. All d. glans penis and prepuce cold, urine colourless.- 12th, 8 a.m., 2 gr. As yesterday, only greater urging to urinate.- 13th. Urging to urinate continues this d. and next, declined the 3rd d. During this time he had drunk very little.-Jan. 30th, 8 a.m., 3 gr. 10 a.m. , pulse stronger, palpitation of heart, congestion of head; itching in skin, particularly offace.-31st. 3 gr., same symptoms as yesterday, and, in addition, some small heat spots, especially on 1. side of face to neck, which lasted 2 d. ( MARTIN'S provings, Hom. Viertelj ., x, 81.) 2. FRIES took Dec. 12th, 13th, and 14th, 1 gr. Loss of appetite all 3 d.-13th . Nausea after breakfast ; in e., dull headache and great itching in various parts of body, especially r. elbow.- 14th. Noon and afternoon, tensive pain in cardiac region ; in e., headache and itching as before.-15th. After breakfast, headache in r. temple, vertigo and inclination to vomit; increase ofthese symptoms till e.,when they went off after dancing.-16th. Same symptoms but slighter ; frightful dreams. (Ibid., 82.) 3. GRAFE. Jan. 30th, 1 gr. No effect.- 21st. 2gr., after some d. the whole face and all the body covered with papules. (Ibid.) 4. GÜNTHER. Dec. 11th, 6 a.m., 1 gr. 7 a.m., violent sneezing for h ., then profuse epistaxis till 8 a.m. In afternoon and following n. frequent urging to urinate, with scanty and painful discharge, urine rather turbid.- 12th, 6.30 a.m., I gr. At noon great nausea, followed by severe vomiting of mucus. All d. and n. frequent urging to urinate, with a peculiar itching in urethra and scrotum .- 13th, 7.30 a.m., urging to urinate, with burning in urethra.- 14th. Same symptoms.- 15th. Better.-16th. Urging to urinate worse, very sleepy in e.- 17th. Urging slighter.-Jan. 30th and 31st and Feb. 2nd, m., 1층이 gr. Great heat, especially in face, great anxiety, increased flow of urine, itching in all limbs, restless at n, in m. refreshing sleep. During d. very weak. (Ibid., 83.) 5. HILPERT. Jan. 22nd, 6 a.m., 1 gr. Soon slight pressure in stomach. Afternoon, shooting in upper maxilla and upper lip. -23rd, m., 1 gr. Noon, tickling in l. cheek, soon afterwards drawing pain in l. temple. 6 p.m., urging to stool, con. tinual pain in r. side of sinciput. II p.m., violent cutting in stomach, with great VOL. II . 44

flatulence, urine turbid, pain in bladder when urinating.- 24th. From 5 a.m. violent cutting in abdomen, with flatulence and urging to stool lasting till went off in afternoon. Tickling feeling alternately in various parts of face, especi ally noon, about inner canthus of eyes and about alæ nasi ; very cheerful humour till bedtime.- 25th, 7 a.m., 1 gr. After soup at 10 a.m. suddenly cutting and pressure in stomach, soon going off. Agreeable feeling about eyelids and nose. frequent sneezing, especially about 11 p.m., after which great Wea irritati kneonssininnos lime.bs , 26th, m., in bed, pressure and cutting in stomach, recurring after taking soup, weariness of limbs. Afternoon, repeated violent sneezing. E., tickling in face, great desire for work, repeated sneezing, some blood discharged from nose, great irritation in root of nose.- 30th, m., 1 gr. E., considerable headache, with redness and heat of face.- 31st. 1 gr. 9 a.m., quick pulse. 3 p.m., strong pulsation like a jumping in region of r. 4th and 5th ribs. 8 p.m., slight headache, which recurred more severely at 11 p.m.-Feb. 2nd. I-gr side of chest; great pulsation in l. elbow. quiple a.mo. ,pim 3r. d.10 Tw ck spul thr onse,for obb ehe ading andinoner. on r. side of lower jaw, with pain. Inflammation of Meibomian glands in 1. lower lid, slight headache, toothache, noise in ears and humming in forehead. -7th. Several pimples on neck and 1. corner of mouth; pressure in eyes for several d. (Ibid.) 6. HORN. Dec. 12th, 6 a.m., 1 gr. All d. chilliness.- 13th, 6 a.m., 1 gr. Chilliness, constant urging to urinate, urine turbid ; very tired and ill.- 14th. Tired feeling continues , also urging to urinate, must do so every h., though he has drunk little, urine turbid, sexual desire very much diminished.-15th . Secretion of urine much increased, must urinate 24 times during d., but not during n. Micturition, with contraction in urethra and pain in bladder; urine very slimy and turbid.- 16th . Urging to urinate less,urine clearer and passed with little tension. Sexual desire increased.- 17th. Urging to urinate less frequent, but still oftener than normal , no pain. Nerves much affected; good appetite; urine clearer, but still has sediment ; frightful dreams . (Ibid. , 85.) 7. KUNTZMAN. Dec. 12th, 1 gr., after h. repeated violent sneezing, thereafter scraping pain in trachea, which goes gradually lower till it seems to be in the finest ramifications of the bronchiæ, excites coughing, which brings away small lumps of viscid mucus ; all symptoms went off in h.- 13th. yesterday. After 8 d. took 1 gr., no symptoms . After 14Id.grfelt freequesym sam nt urg ptoing to ate, with burning in bottom of bladder, increased sexual., des urinat ire. Jan 29tas . ms h. 1 gr., immediately scraping in fauces. After h. pressure in l. eye, transient. Soon afterwards chilliness all over skin, cold hands . Urging to stool, with liquid stool. Afternoon, prickling feeling in l. leg where the calf-muscle goes into tendon.-- Feb . 2nd. 1 gr. , after h., urging to stool, liquid stool, flatus, chilliness all over skin, cold hands for h. Afternoon, drawing shooting pains in course of 1. musc, rhomboid.-3rd . I gr. , same symptoms as 8. MARTIN. Dec. 11th, m., 1 gr.yesAftterer day. h. fro l headache, pressive pain in nta86.) (Ibid., r. hypochondrium. After h. tearing pain on back of 1. hand, pulse spasmodic, 76. After 1 h. itching on back of both hands, eruption of wheals, which soon disappear, but recur in e. During d. copious micturition, with pressure in abdomen ; urine clear.- 12th, m. , 1 gr. After 1 h. much flatulence and urging to stool; during d. increased micturition.-Jan. 2nd, m., 1 gr. Feeling of lateral contraction of tongue; much sneezing afterh. Contractive stitches in chest ; rheumatic pains in forearm ; itching on back of 1. hand and appearance of 2 pimples. Much yawning.-Feb. 2nd, 6 p.m., 1 이 gr. Flat taste. After 10 m. in open air dyspnea like chest- cramp ; pressure in stomach. E., great drowsiness. Atn. dream of flying some feet above earth on the back.-3rd, m., 1 gr. Afternoon, increased flow of urine ; at night restless dreams.-4th. In e. an itching vesicle on back of 1. hand ; next m. same on back of r. hand.-5th , m., 100 gr. Increased flow of urine.-July 25th, 10 a.m., th gr. Afternoon, increased secretion of urine. unce.omfFul flatulent movement in bowels. Next m. woke unusua10llyp.mear witehdos .,lysam ortnes abls,e oppressed feeling in upper part of abdomen, great irritability of senses, headache ; discharge of much flatus ; violent cutting pains about navel. Noon, unusual vertigo and headache, fulness of abdome n, much flatus. The vertigo and frontal headache and a kind of nausea last all afternoon till e. Next m. long sleep, with agreeable dreams about travelling. (Ibid.)

IODUM. 691 9. OEHLER. July 27th, 9.30 a.m., Tooth gr. , and same dose at 4 p.m. Oppression, anxiety, quickened circulation, and congestion of head, not for long. -28th, 6.30 a.m., I gr. No effect. (Ibid., 88.) 10. REICHMANN. July 28th, 6 a.m., 1 gr. No effect.-30th, 6 a.m., 2 gr. Only a little eructation.-Aug. 30th, 6 a.m., Tooth gr. 8 am , nausea, eructation, repeated inclination to vomit, but without vomiting ; rumbling in stomach. 4 p.m., a vesicle on tongue, took again Tooth gr . 11 p.m., great fatigue after a short walk, dulness of senses.-31st, 6 a.m., 1 gr. Nothing but some mucous expectoration. (Ibid.) 11. VULPIUS took, Dec. 11th, 1 gr. No effect.- 12th. 1 gr., chilliness all over body,with violent headache lasting all d. Spasmodic twitching in r. lower eyelid.- 14th. 1 gr., all d. great drowsiness. (Ibid.) 12. WERTHER. Dec. 11th, 6.30 a.m., 1 gr. 9 a.m., formicating pain in pit of stomach, going down to umbilical region and lasting till 11.30 a.m. 6 p.m., continued tired feeling in r. knee, which lasted till next m.- 12th, 6 a.m., 1 gr. Increase of last symptom.- 13th. I gr. 10 a.m., recurrence of pain in pit of stomach for h.-14th. Itching inglans penis; e., shooting in urethra.- 15th. This pain increased, especially in e., and lasted till next d. (Ibid., 89.) 13. WILCHER, Aug. 25th, after breakfast, took 1 gr. Soon nausea, then flatu. lence, thereafter pain in r. zygoma and orbit. After 2 h. pain in 1. side of occiput, under 1. humerus, and especially in l. index and in r. short ribs, which soon went off. Pressive, often tearing pain in r. upper teeth and 1. molars. About noon, eructation and no appetite. After dinner slight tired feeling. In e. pain in l. eyeball.-26th. I gr. , nausea, flatulence, eructations, pain in l. side of occiput, which darts through head to orbit. The toothache persisted, was pressive and intermittent. Appetite still nil. The pain in eye and ribs continued. Cross in e., when he took I gr. N. quiet; next m. woke earlier than usual, with nausea and weariness. Occasional subsultus tendinum in all limbs. Itching in hypogastric region and inside of thighs. The pains in eye and occiput, in teeth and 1. parts, lasted some d. (Ibid.) 14, 15. Indigohas also been proved by LEMBKE (A. h. Z.,xlv, 338) and NENNING (Ann. d. hom. Kl., iii, 229), but their results are too voluminous and trivial alike for reproduction here .- EDs . II. Poisonings.- 1 . IDELER treated 26 patients with I. for epilepsy, beginning with scruple, increased gradually to oz. and oz. doses. "At first the patients vomited frequently, without any straining or derangement of the digestive organs ; after a few d. this ceased and the patient had 6 or 8 stools a d., sometimes accom. panied with slight colicky pains ; after a short time the purging diminished, the matter passed assumed a fluid character, and this state continued as long as the I. was administered, without the appetite or digestive organs being injured." (Lancet, 1834-35, ii, 335.)