Chelidonium majus

Volume II — Main text

CHELIDONIUM. Chelidonium majus, Mill. Common Celandine. Nat. Ord., Papaveracea. 1. Provings.- 1 . HAHNEMANN, Mat. Med. Pura, vol. iv oforiginal, vol. i of translation. Contains 28 symptoms from self, 122 from 8 fellow-observers, and 6 from authors. 2. a. Twelve persons took extract, in doses of 2 gr.-ziv in d., and following phenomena were observed : In digestive apparatus, sourish or saltish bitter taste ; similar or purely bitter eructations ; increased mucous and salivary secretion in mouth and fauces, amounting in one prover to actual ptyalism ; scratching and burning in mouth, gullet, and stomach; pressure on stomach ; disgust, nausea, vomiting ; furred tongue, pasty taste ; generally increase, in one case only loss, of appetite ; emission of flatus ; increased (in one case only diminished) action ofbowels. In vascular systemno symptoms. In nervous system confusion of head ; frontal headache ; dimness and weakness of sight ; desire for sleep ; illusions of smell. Urine at one time increased, at another diminished ; darker coloured ; in two cases of resinous odour. b. The tinct. was taken by 11 persons in 5-200 drop doses. The phenomena observed were :-spirituous bitter taste, increased secretion of mucus and saliva, warmth and burning from mouth to stomach ; rare eructations ; slight disgust ; retarded evacuations ; confusion and pain in head ; slight vertigo ; restless sleep and lively dreams ; cloudiness and illusions of sight; ringing in ears ; weariness and disinclination for exertion ; urine generally darker, in two cases of resinous smell. In one person eruption of pimples broke out on face. (Zeitsch. d. k. k. Gesell. d. Aertze zu Wien., Dec., 1844. ) 3. SCHNELLER, one ofthe above, gives following details :a. Ofextr. he began with 10 gr., increased daily by 10 gr., so that last dose was 100 gr. Took altogether 550 gr. Up to 60 gr. gastric symptoms predominated, viz.: disgust, eructations, rumbling in belly, oppression of stomach, white tongue, discharge of flatus from bowels, flying stitches in r. leg, and 3 h. after taking medicine a peculiar burning, with increased redness, of face. Whilst taking 70- 100 gr. , pimples and pustules appeared on face, especially in frontal and temporal regions ; on cheek, ala nasi, and upper lip of 1. side especially they came in groups of 3 or 4. 16 were present at same time ; besides these there appeared a small boil about middle of r. under-jaw. As pustules on face dried up fresh ones appeared, which after leaving off medicine disappeared in a few d. Urine was increased and stools darker coloured ; there was also slight confusion of head. b. Of tinct. (prepared according to Hahnemann's formula) he commenced with 5 dr., increasing, for first 6 d., by 5 dr. daily, afterwards by 10, 20, and 30 dr., so that he took 140 dr. the last d., altogether 625 dr. While taking first 3 doses he noticed feeling of burning in gullet, empty eructations, some increase of mucus in fauces, increased heat of face, urine and fæces somewhat increased, sleep restless. During doses of 20-50 dr., burning and eructations increased, taste was insipid,

tongue furred white, secretion of mucus in hot mouth increased ; in mucous membrane of lower lip a vesicle, filled with limpid serum, appeared, which, after bursting, grew flat and vanished ; there was besides pressive frontal and occipital headache. Under the last doses of 70-140 dr. appeared drawing pains in muscles of chest and back, as also in teeth ; also papular exanthema with red base on upper lip and r. cheek ; disgust, eructation, fulness in abdomen ; burning in urethra, frequent call to micturate, with increased secretion of pale clear urine ; sleep restless. (Ibid., 1846, ii, 405.) 4. Dr. TESTE proved 6th dil. on 4 persons, a globule being taken in m. for 2 or 3 d., afterwards more or less frequently. a. Mr. A-, æt. 37, nervous and irritable, subject to muscular pains, intestinal irritations, and leucophlegmasia ; generally very sensitive to medicinal action. In 10 m. after Ist dose profuse emission of yellow and foaming urine, like beer. In h. dull, deep-seated pain in renal region. In 1 h. pain at r. shoulder, and sore-throat as from a cold ; pressure on rectum and urging to stool (unusual at this time), with active appetite. In 3 h. itching ofeyes, lachrymation in open air,and oppression of chest when walking. In 4 h. another emission of foaming urine ; neuralgic pain at 1. eyebrow ; trembling of head and hands ; tension in both iliac fosse ; itching at hips when walking, as if sweat would break out, though temperature is pretty cool. In 5 h. burning pain at tip of 1. elbow ; numbness of both hands. In 6 h. (2 p.m.) sort ofgeneral numbness, with somnolence, unconquerable aversion to movement, and confusion of ideas as if one were half asleep, without shuddering or increase of temperature of surface. These symptoms disappeared gradually about 3, nothing remaining but dull pain in lumbar region (which continues until n.), lachrymation as before, and (now and then) itching and slight smarting at orifice of urethra. In e. in bed, before falling asleep beating in both temples, sense as of strong determination of blood to throat and upper chest ; a few dull beatings in these parts, followed by cutting pains in lower abdomen. 2nd d., urine natural ; several small thin stools, preceded by a few slight cutting pains ; slight irritation of throat (not felt while swallowing), causing occasional small paroxysms of cough, with spasm of glottis during expiration ; burning continuous pain at spot size of dollar to 1. of sternum, two inches below clavicle. At 2 p.m. similar paroxysm to yesterday's, but not so long and intense as on 3rd d. In m. onwaking, eyes swollen and agglutinated ; slight rheumatic or contusive pain here and there in upper part of body, with a few red indolent pimples ; towards midday, at seat of burning pain (which continues) a red spot appears ; later, similar sensation at points of shoulders, trunk, and arms (very unpleasant, and continuing till end of proving) ; same drowsiness about 2 p.m.; two light-coloured stools ; irritation and cough as yesterday ; in e. in bed pressive stitch in r. temple, ceasing when lying on affected side, but immediately recurring on turning round, for h. 4th d., throat sore in m., velum feels elongated ; cough as before ; skin on chest and neck feels dry and as if bruised. About 1.30 p.m. dull and heavy deep-seated pain in whole r. chest and shoulder, without cough, but with embarrassed respiration ; this pain, which is at times

accompanied with dull beatings in chest, does not allow him to draw a long breath, but is not perceptibly aggravated by motion of arm ; it is particularly felt in axilla and under shoulder-blade ; there is a sort of numbness of the muscles in r. hypochondrium and whole r. side of face, neck, and head ; he apprehends pneumonia imminent, has great anxiety and constant restlessness. This painful state lasts I h., and decreases gradually, returning about 6.30, after a good dinner, which he relished, and commencing with vertigo. 6th d., slight paroxysm of dyspnea about 2 p.m.; red rounded spots on palmar side of forearm, of size of half a franc, accompanied with burning pain ; no stool ; lachrymation in open air. 7th d., irritation of throat on waking ; hollow and unfrequent cough ; prostration ; no appetite. Intolerable pain in heels as if these parts had been wounded by too narrow and too short shoes (this symptom had existed slightly for 3 or 4 d. previous) ; red indolent pimples, here and there, on thighs and buttocks ; other cutaneous symptoms become more and more intolerable. At I p.m. chest again affected ; deep-seated pain in r. side as from an abscess ; pulsation under upper sternum, synchronous with pulse ; respiration embarrassed as if the air passages were filled with a foreign substance ; dry skin without any increaase of heat ; pulse 86 ; no cough ; has less anxiety than d. before, but more prostration. Region of liver slightly painful to pressure. Painful numbness at r. hip and knee. From this period experiment was carried on at intervals only, with very vague results, previous symptoms disappearing almost immediately. b. Mrs. A- (No. 3 of Cedron, q . v.) . Ist d. , at 8 a.m. , h. after Ist dose, vague pressive pain in r. shoulder ; extremely profuse emission of whitish foaming urine. 8.30, dull, sometimes throbbing pain in loins ; painful pressure,just below r. ankle, and same kind of pain in r. heel, rendering walking painful (it feels as if part had been bruised by tight and hard shoes, but no relief is given by taking off shoes). II, sore-throat, as from taking cold ; another emission of foaming urine. 2 p.m., for h., drowsiness so marked, even in open air, that she is near falling asleep while walking. 4.30, weight in forehead. 5, at dinner, unusual and marked aversion to cold things ; she does not drink on this account. After dinner luxation pain in 1. hip, which scarcely allows her to walk ; pain in ankle becomes as from a sprain. About 8, while walking, pain in hip extends to knee, which is so painfully affected by it that whole joint feels as if dislocated. In e. in bed, slight oppression of chest ; still some irritation, with occasional spasmodic feelings, in throat before falling asleep. 2nd d., sore-throat on waking ; lassitude in extremities ; white-coated tongue, not much appetite ; slight drowsiness about 2 p.m.; a little oppression and loose cough about 6 p.m.; luxation pain in knee and foot continues ; is peevish. 3rd d., sorethroat worse, with a little cough now and then ; coated tongue, not much appetite ; benumbing pain in whole r. side of chest ; a red, flat, not very apparent spot between breasts, with burning itching. Some dyspnea from 1.30 to 2 p.m.; apathy the rest of d.; at dinner everything she eats seems to taste badly ; n. less quiet ; a little dry heat on skin. 4th d., sight of r. eye misty on waking ; acute neuralgic pain

at r. temple (before dose). An unforeseen journey interrupted experiment.

c. Miss R-, æt. 10, blonde, sensitive to drugs when sick, after taking first doses perceived pungent heat on skin, pulse feverish, tongue coated white, vertigo on sitting up ; rush of blood to head, throat, and upper chest ; violent and slightly spasmodic cough ; dull pulsations at base of r. lung and liver ; pulse up to 90 in e.; sweat at n. Mother ofchild became frightened, and proving was discontinued. d. Mrs. X-, æt. 32, blonde, not very sensitive to drugs. Experienced only following symptoms:-excessive and continued apathy, a sort of aversion to exercise, spirits remaining unaltered ; neuralgic pain about r. eye, especially while reading by candle-light, also a sort of fluttering before this eye, scarcely permitting her to read ; embarrassed breathing, especially while reading, without coughing ; pulse more frequentthancommonly ; cool and dry skin. (TESTE,Mat.Med., sub voce.) 5. NENNING. " From the root " [no further information]. Vertigo, and immediately thereafter shuddering all over body, he loses consciousness for a moment, and feels as if he had been turning round and round (1h. ) ; much itching about head and face ; no distinctive or noteworthy symptoms elsewhere. (HARTLAUB and TRINKS, Arzneimittellehre, i and iii.) 6. Dr. LIEDBECK took a teaspoonful ofthe pure juice. He only felt a little excited by it.-2 d. later he took another teaspoonful. This caused painful accumulation of flatulence about umbilical region, followed by slimy diarrhea for 3 d. Thereafter was well, but for some weeks was so much affected by smoking tobacco, that he had to give it up. Although in the habit of smoking a couple of cigars or pipes per diem, it now brought on violent cardialgia at n., with burning pain and acidity from cardia up into throat. He had formerly suffered from similar cardialgia when he used to chew tobacco. He believed this sensitiveness to the action of tobacco after the C. was due to the irritated state of the m.m. of stomach and bowels caused by the diarrhea. He afterwards made a proving of C.-May 19th, 7 a.m. , 5 dr. tinct. 10 a.m., pressure in stomach aggravated by external pressure for several h. II a.m. great quivering of r. upper eyelid.- 21st, 7a.m., 10 dr. 9 a.m., pressure of stomach commenced. II a.m., nausea and flow of saliva, severe stitches in pit of stomach. I p.m., a prick in 1. nipple.- 24th, 6 a.m., 20 dr. 7 a.m., contractive spasm in gullet, followed by nausea and salivation. 7.45 a.m. , pressure in stomach as from a blunt instrument, increased by external pressure, at same time an obtuse pain like urging deep in bladder ; urging to urinate constant, and cutting in urethra for 2 or 3 h., even after urinating. 8 a.m., drawing in cervical muscles and in dorsum of 1. foot ; the stomach-ache lasted several h.- 28th, 7.30 a.m., 30 dr. Soon, nausea. 8 a.m. , urging to urinate, lasting 2 h.; pressive pain in l. knee, 1. leg and forehead ; shooting in orifice of urethra. 8.30 a.m., much rumbling in abdomen ; wandering pains in joints of lower extremities, especially the l., almost only when at rest, also in upper extremities, forehead, sides of nose and bones of superior maxilla.-June 3rd, 7.45 a.m., 50 d. No symptoms.- 4th, 6 a.m., on rising violent cutting in stomach and umbilical region,

increased by pressure, for 2 h., nausea.-6th, 7 a.m., 100 dr. 9 a.m., pressure in sinciput and occiput. 9.30 a.m., great coldness in back for 5 m., also cold hands for I h . 10 a.m., soft stool. 3.30 p.m. , stool after dinner, soft and bright coloured, with straining, followed by cutting in anus ; severe shooting in larynx with constrictive sensation, flow of saliva and tears; dry cough . II p.m., soft stool.-7th, 6 a.m. , on rising copious liquid, bright yellow stool with much mucus, no pain. 10 a.m., stool ; pressive drawing in r. knee, especially when bending it, and in bones of 1. side of face.- In the e. of 6th, when he stooped low, there was a compressive pain deep in chest towards vertebræ, very violent. The same pain occurred on 7th, when walking quickly, blowing nose, sneezing or stooping, but was more external along the spinous processes of thoracic vertebræ.-8th, 10 a.m., soft stool, later normal stool.-12th, 7 a.m., 150dr. Nausea, much saliva ; pressure in stomach, increasing later. 9 a.m., pressure and heaviness in forehead, also later occasionally. 9.15 a.m., obtuse pain on 1. side under ribs, later on r. side, and more severe there, it comes and goes. 9.30 a.m., shooting in r. side of chest, about nipple, when sitting, not affected by breathing, without cough . 10 a.m., same pain on 1. side ; bruised pain in r. shoulder ; stool normal, pain in forehead like what occurs from a very costive stool. 10.30 a.m., pain in r. shoulder very severe, worse when arm is at rest, lasted h. II a.m. , shooting in orifice of urethra. 3 p.m., after dinner, soft greenish stool ; cutting pain in rectum and higher. 4 p.m. , pressure in r. ankle. Woke at n. from severe pressure in bone of r. upper maxilla.- 17th, 7.30 a.m., 200 dr. 8.30 a.m., boring in bones of r. leg ; heaviness in forehead ; severe pressure on sternum, afterwards in l. index. Soft stool at 10a.m. and7.5 p.m. (Allg. hom. Zeit., Dr. BUCHMANN, æt. xlv, 43 ;26.sanguineo-nervous ) ; very fair ; powerful muscular system, with tendency to corpulence ; appetite good. Fruit in every form causes slight acidity of stomach, especially after meals ; so does light wine, as Rhenish and Moselle. Coffee only agrees well with plenty of cream and sugar ; after acid food it causes flatulency. Anamnesis : catarrh and toothache after catching cold ; excepting the eyes, all senses very acute ; tendency to soft stools ; spirituous drinks cause slight headache, weariness, ebullition of blood, yet are a necessity after bodily and mental exertion ; noparticular predisposition to any disease ; approach of change of weather produces languor, indisposition to work, and low spirits. a. 1861, Oct. 27th, 9 a.m., took 10 dr. of tinct. In 10 m. pain in l. meatus auditorius externus ; ears as if stopped ; drawing pain in upper and under 1. molars ; burning in mucous membrane of nose towards tip, as in coryza; drawing pain in l. leg from hip to foot ; tensive pain from upper part of 1. pectoralis up to neck ; stitch through 1. upper jaw ; pressive pain on 1. side in ribs, and in nape muscles of 1. side ; then between ribs and hip-bone on 1. When pain commences in a new place it ceases in the previous place. Itching of anus ; sensation of heat in 1. half of head, beginning from 1. ear ; drawing pain from 1. shoulder down to 4th finger. Inth. pain in ribs, r. and l., on bending thorax to that side ; paralytic sensation in l. leg ; VOL. II . 5

pricking pain in l. hip-joint ; tearing pain over 1. eye ; burning in intestines on 1., close to navel, and also in 1. hypochondrium ; lachrymation, repeated quivering and blinking of eyelids ; pressure in hind part of r. temporal bone ; drawing pain in 1. shoulder-blade, and from thence to 1. side of chest; feeling of cold in abdomen ; burning and itching on a part of skin of hand that had been pierced by a thorn ; tension in front of chest ; pain between 6th and 7th ribs on r. side on moving chest towards opposite side ; sudden strong inclination to urinate ; burning pain in skin over 1. corner of mouth. After dinner sufferings ceased. 3 p.m. , pain again in 1. side of chest ; sensation of paralysis and cold in legs till e.-28th. After rising pain on outside of 1. arm above elbow. 9.15 a.m., took 30 dr. In 5 m. drawing pain through teeth of upper jaw ; pain above and behind r. ear ; pressure on 1. side ofchest. 9.30, burning in eyelids ; quivering and blinking of eyelids, with tears ; pain on outer edge of 1. shoulder-blade ; tearing pain over 1. eye. 10, sensation of stopping in ears ; dull stitch through 1. hypochondrium ; frequent eructation of wind. 10.15, pain over 1. ear ; drawing through upper molars of that side ; pain as if bruised in 1. side of chest and 1. hypochondrium, aggravated by movement ; pain over 1. eye. The pains are not violent, last only a short time, change their place, and return to the former places, till midday. b. Nov. 5th, 9.30 a.m., took 90 dr. In 2 m. drawing pain through all teeth ; intoxication,withvertigo; drawing in muscles ofnape ; pain in nasal cartilages ; stiffness in neck ; heaviness in head ; rumbling in bowels ; confusion in head, as if after spirituous liquor ; constriction in throat ; pressure on chest ; inclination to cough, repeatedly ; pain through both hypochondria, and in r. shoulder-blade. 9.45. burning pain about navel, in intestines, soon passing off; hands swollen through prominence of superficial veins ; drawing pain through r. shin-bone to instep ; blinking of eyelids ; stitch through inner side of l. forearm ; continued drawing through upper jaw and teeth ; shivering ; sleepiness . In writing, the letters run into each other and are more legible when further from eyes. 10.30, nausea ; sudden call to urinate ; burning in urethra, near glans ; pain intemporal bone behind ear ; pressive pain close under 1. shoulder-blade, and in ribs of 1. side, on moving. II, the back, on moving, as if bruised ; feet cold ; undulating pain in 1. side of chest ; pricking pain through abdomen ; paralytic feeling and heaviness of arms, as if weights were hung on them ; pains in knees as if after a long walk ; pricking and drawing pains in 1. forefinger, and on under side of 1. great toe, and lower extremity of 1. ulna-the skin, on these parts, smarts as if burnt ; uncomfortable feel all over ; stiffness in neck ; drawing pain through vertebral column forwards to chest and from thence to abdominal integuments as far as navel ; cold shivering all over, frequently repeated, upon which confusion of head ceases, though pains in chest and spine continue ; pain close over 1. elbow ; itching in terminal phalanx of r. middle finger at bend ofjoint ; pain in r. knee-pan ; helplessness of hand in writing ; unusual hunger before meals ; in walking, powerlessness of lower extremities, especially below knee ; no suffering for a whole h. after dinner. 2 p.m., drawing pain in spermatic cords; pain at every

step under 1. heel and under r. inner malleolus ; pains in chest, nape, and spine, return as in forenoon, and last till e. 6, pressive pain in occiput, extending round to forehead ; paralytic drawing in knees and legs ; tensive and pressive pain in whole of back, aggravated by stooping, and extending round towards chest. 8.30, pricking pain in r. meatus externus ; pressive pain on 1. instep.-6th. Unusual awaking at 4 a.m. with slight twitching of muscles here and there ; third and ‫دو‬ fourth fingers on each hand " asleep ;" pressure in stomach with accumulation of wind ; pain in back, as if after excessive muscular exertion, on turning in bed ; pressure in upper eyelids ; soon fell asleep, but in a short time awoke again, in a gentle perspiration all over ; felt friction of upper eyelid on eyeball on moving both ; itching of anus ; chilliness ; pressure on front of chest with difficulty of breathing. 8 a.m., great weariness and sleepiness on awaking ; hands and feet cold ; drawing pain through muscles of chest, quite to umbilical region, varying in intensity ; pain close over l. elbow, then in r. shoulder, in 1. side, and in r. forearm, drawing from one part to the other ; feeling in muscles of neck as if neckcloth were tightly tied. On going into another room to fetch a book had to spend some m. in thinking what he had come for. No symptoms all d.; but 2 h. after supper pain in fore part of parietal bones. In thorax and extremities wandering pains as before. About II p.m., on going home, whilst making water, a sudden fit of asthma ; can only breathe quickly and with exertion, as if he must choke with anguish ; thereupon, nausea, alleviated by eructation. Difficulty of breathing continues still after going to bed.-7th. Immediately after midnight awoke with oppression ofchest and short breathing ; itching on 1. instep ; violent pain form. in l. arm, extending down from shoulder to outside of it. In h. sound asleep till 4.45 a.m. Awoke with gentle perspiration all over ; violent itching over scrotum ; pain in head, as in e. before ; drawing pain through upper teeth on 1., in l. shoulder-blade, and through 1. arm ; chilliness ; paralytic pain in thighs, close above knees ; drawing pain through whole back. 8 a.m., four lax stools in quick succession, of ordinary colour ; moist coryza for 2 h. with hawking of mucus ; quite well all rest of d. Great inclination for wine ; drinking it brings on neither determination of blood to the head nor headache, both which, at other times, followed from taking the same quantity.-8th . On waking in m., heaviness in head ; dull headache in forehead all d.; stiffness in neck. 4 p.m., drawing pain in back, and tensive pain in sides of chest ; drawing pain over navel ; pain in r. shoulder ; anguish and oppression of chest ; difficulty of breathing ; longing for fresh air, in order to breathe more easily ; increased feel of heat over whole body. Pulse 90 (usually 60-65). Serious indisposition ; heat in head ; hand trembles in writing ; feeling all over as in influenza (having once had it formerly) . Towards evening gradual disappearance ofsymptoms, all except confusion of head.-9th, 4 a.m., on waking, gentle perspiration all over, with normal pulse ; slight, merely tearing pain in head over 1. eye, and in it ; lids ofeach eye agglutinated with dry mucus, and can only be opened by a strong effort ; pain like a wound in last lumbar vertebra, as ifdislocated or broken ; stomach-ache for an h., with

eructation of air, relieved by lying on 1. side with legs drawn up (this symptom has shown itself before, after eating shortly before bedtime) ; tonic cramp in flexors of fingers, the closed hand can only be opened with difficulty, whereupon no more cramp occurs ; immediately on awaking, frequent stretching and yawning, with pain in fauces, as in catarrh ; frequent dry cough. Sound sleep from 5.30 to 8. At breakfast a remarkably yellow tinge of face was observed, especially on forehead, nose, and cheeks. Looked in face like a jaundiced person, white of eye being dingy yellow ; red of the cheeks has dark tinge from mixture of yellow ; stool thin, pappy, bright yellow, as in infants . Quite well all d. except some pain in r. testicle.-10th. At4.30 a.m., on awaking, gentle perspiration all over ; pains in the lowest lumbar vertebra ; pressive stomach-ache, relieved by eructation, for I h.; then yawning and stretching, with cessation of pain after discharge of Alatus. Slept till about 8. Yellow colour of face is only slightly perceptible. 6 p.m., pressive headache all over ; drawing pain in occiput, through r. upper molars, and through two middle incisors oflower jaw, over 1. eye, and in r. fourth finger ; stitches in 1. side towards shoulderblade ; tensive pain in whole thorax ; pain in r. hip on rising from seat ; the toothache extends high up into r. temple ; drawing pain in 1. middle finger, and in front of chest towards abdomen down to navel ; all d. long itching in inner canthus of 1. eye. Stool pappy, bright yellow. -11th . Awoke as usual about 7. Skin less moist ; shivering ; drawing pain in testicles and spermatic cords ; pressure in abdomen close over pubes ; tension and pressure in perinæum ; pressure in eyeballs, and burning in lids ; drawing pain on inside of r. tendo Achillis. After rising, drawing pain through abdomen and 1. forearm ; pressure in nape. In writing, the letters run into each other. Pain on outer side of l. wrist. No more suffering after 9 a.m. Colour of face normal ; stool bright yellow, pappy.-12th. On rising, about 4.30 a.m., skin somewhat moist ; drawing, pressive, tensive pain in testicles and cords, with pressive pain in occiput for 1 h.; then, drawing pain in under part of rectus femoris, and from there to knee, especially in knee-pan, upon which it gradually ceases ; eyelids heavy, perceptible friction of the lids with the eyeballs on opening them. At 8 a.m. pappy dark-brown stool.- 13th- 17th. No symptoms. All this time, inclination for wine and dislike to cheese. During the proving he was obliged to make a heartier breakfast, to avoid the sensation of exhaustion and craving hunger, which otherwise came on. Spirits from 13th to 17th lively. c. Change of weather on 17th brought back some of the symptoms, but by 20th they had again disappeared. Dec. 3rd, 10 p.m., took 2 dr. of tinct. in water. In 5 m. burning in 1. nostril ; drawing pain in l. upper incisors, and from thence to l. upper and lower molars ; drawing pain in r. lower extremity, through 1. leg, on the inner side of r. thigh, and in whole of back ; stitch in tip of tongue on l.; sensation as if skin of the forehead was contracted over 1. eye ; burning on that part ; on rubbing it, sensation as if one were pressing a spot which had been violently bruised the d. before ; ssensation in throat as if it were compressed ; short fit of coughing ; swollen feel of 1. hand, sen

sation ofheat on its back, veins of both hands prominent ; 1. hand feels heavier on lifting it ; drawing through 1. side of occiput. In bed, drawing pain behind and above r. ear.-4th. Slept well. Much flatus at usual stool in m.; stool of brighter colour than usual ; tormenting pricking itching of small spot of skin on outside of 1. arm, close over wrist. 10 a.m., took two spoonfuls of a solution of 10 dr. of tinct. in a glass of water. Drawing pain on outer edge of 1. shoulder-blade ; frequent yawning. Spirits lively. More exact observations were interrupted by journey into country. One h. after dinner, great sleepiness. Pressure on under side of glans and orifice of urethra. On awaking from a siesta of 2 h. (at other times only h.), dryness of throat, remarked on accidental empty swallowing, which disappeared after one deglutition ; drawing in lower extremities ; pressure on occiput. In e., drawing in back, and in front in lower half of thorax, with difficulty of breathing, and pressure in throat as if it were compressed ; pain in patellæ on walking. About 12, just before bedtime, 3 dr. of tinct. Weariness disappears again, so that he spent h. longer reading in bed without being tired, although what he reads does not much interest him. In h. after dose, painful and tormenting sensation in glans, similar to what he had felt after strong erections ; burning in orifice of urethra for h., followed by discharge of a drop of fluid. In m., pain in deltoid and biceps of 1. arm on moving it, so that he cannot put coat on without help ; distraction of thoughts, so that he forgets to pull on drawers, and in shaving rises from chair before lips and chin are shaven. Pain in arm all d.-5th. At 8 p.m. took 5 dr. in water. In 10 m. confusion of head ; piercing pain over 1. eye, in 1. molars ; burning in intestines around navel ; (laziness, indisposition to labour) ; burning in 1. upper eyelid. In writing, letters seem less distinct, as if lamp did not burn bright enough ; ( inclination to lie down). (The bracketed symptoms occur also when the weather is about to change. ) The same sensitiveness in glans and urethra as the d. before, but not so much. At n. frequent sudden starting out of sleep, with violent pains in 1. upper molars ; teeth seem too long, the pain is aggravated by chewing; nostrils surprisingly dry, as if stopped up ; eyelids can only be opened with difficulty, as if they were swollen, and smart when this is attempted, as if sand were in them ; burning in l. upper lid ; nausea ; cutting in intestines. On again waking, pressure on chest and constriction, he cannot draw in enough of breath at each inspiration, and therefore soon expels the air to inspire more ; a few very deep inspirations relieve this distress . Towards m. gentle perspiration all over ; pains in 1. side, drawing from thence to back, aggravated by movement.-6th. Pain in last two upper 1. molars which prevents chewing all d. (the anterior tooth being sound) ; drawing pains here and there in l. side and back. The pains in 1. arm gone.-7th. Toothache in same molars all d., also at n., waking him out ofsleep. Does not know whether pain is in upper or lowerjaw ; only the two upper teeth painful to touch.- 8th. Just as 7th. -9th. The two teeth are only sensitive when touched. 10th. At 12 p.m., 5 dr., shortly before bedtime. Before going to sleep, sensation of warmth all over body, with oppression ; drawing through upper

incisors. Restless sleep, frequently awaking, when he had dreams of various symptoms, of which he had no recollection in m.- 11th. On awaking, burning itching in eyelids ; gentle perspiration all over ; stoppage of 1. nostril ; drawing in back ; weariness.- 12th. At 10 a.m. 10 dr. In 1 h. drawing pain in teeth ; burning in nostrils ; drawingpain through hypogastrium ; cutting pain through epigastrium ; nausea, diminished by eructation; pinching in intestines as sometimes before stool ; spirits lively ; increased briskness ; pressure on eyelids on awaking in n.; paralytic symptoms in limbs, especially in legs ; drawing pain in 1. forearm and on back of hand ; pressure and tension in perinæum.-13th. Drawing in back, and on outer edge of 1. shoulder-blade ; tension and pressure in perinæum ; drawing in nape ; coldness in legs. d. March 13th, 1862, 10 a.m., chewed small leaf of vernal shoot and swallowed juice. It coloured saliva sulphur-yellow ; taste disagreeable, rather sweetish bitter, much more acrid than leaves of plant when flowering, with slightly acid after-taste ; burning in whole cavity of mouth, as if after Cayenne pepper ; burning of lips, most of all on tip of tongue, with feeling of heat in mouth ; burning down œsophagus quite into stomach. In 10 m. sensation of swelling in larynx, with pressure on it and trachea ; nausea ; sense of fulness in abdomen ; grumbling in intestines ; vertigo and reeling. Inth. unusual urging to urinate ; clonic spasms in eyelids ; on trying to keep them open they are forcibly closed ; loss of power in walking ; pressive pain in middle of r. rectus femoris ; hot feel in teeth ; oppressed respiration ; after dinner weariness, and sound sleep + h. In afternoon till 4, great weariness and indisposition to exertion ; about 5 a very hot cup of coffee was taken eagerly, when the high temperature of the beverage was beneficial ; pressive pain over 1. eye ; burning in l. eyelids till bedtime ; pressive, drawing pains in 1. side of occiput, and also over mastoid process of same side ; periodic pricking pain in 1. parietal bone; paralytic pain in 1. shoulder and whole of arm ; stiffness in back and between shoulders ; drawing pain in l. forefinger ; frequent fits of coughing ; sense of stoppage in ears, with singing in them ; burning pain on cheeks near ears ; cutting in intestines close over navel ; frequent yawning. Just before bedtime itching burning close under pit of throat. In n. awakened by his wife, who was disturbed by his loud-toned, rapid, whistling respiration ; had just dreamt that he had escaped in a deadhouse from a naked corpse, who sprang from the bench and seized him with his hands by the neck to throttle him ; though he was not wont to dream at other times, nor had anything happened which could excite such a dream. Besides, he could not remember that in the dream he had suffered any anguish. After awaking, sensation as if trachea and larynx were narrowed by swelling, with tickling in larynx and short, dry cough ; difficulty of breathing, with great calmness of mind ; slight shivering ; sourish taste in gullet, as if after chewing liquorice or dulcamara ; perspiration, especially in palms of hands ; frequent discharge of flatus ; sensation as if eyelids were swollen, with sand in them. In m. itching on small spot in middle of forehead ; red, inflamed, elevated spot there, with central

tubercle, as when a small boil is forming ; in a few h. it disappeared. e. 14th, 10 a.m., chewed a bit of peeled root, having just previously chewed a little leaf. The root, of the colour of carrot, had also at first a carroty taste ; soon after very bitter, much bitterer than the plant ; and afterwards, like the plant, acrid. Symptoms of mouth were the same as the d. before, to which was added painful drawing in teeth. In 1 h., on fetching a deep breath, painful tension all around on inner side of thorax at its base. Some m. after, stitches, first in l., then in r. of thorax ; eructation ; fit ofcoughing. 2 p.m., drawing pressure in back spreading to sides of chest, in l. molars, 1. temporal and 1. parietal bone ; sensation of heat in 1. side of head, 1. cheek, and r. meatus auditorius . f. 24th.-Took 5 dr. of fresh tinct. at 10 a.m. It burns more on tongue than that prepared in flowering time ; directly after, nausea, and sense of emptiness in stomach, as in bulimia ; obliged to eat white bread to remove nausea ; anguish and oppression ; sense of heat all over ; griping in intestines above navel ; drawing in teeth ; stitch in 1. parietal bone ; feeling ofdetermination of blood towards chest ; giddiness in head. Inh. coldfeel on inside of r. calf in skin, extending to hough, as if these parts were stripped of clothing ; cold feel in toes ; sensation of heat and swelling in hands ; prominence of superficial veins of hands ; feeling of stiffness in nape. Burning on tongue has ceased, and instead of it sensation is as if one had tasted vinegar some time before. Inh. burning in l. cheek with sensation of heat there; drawing in back and sensation of heat in intestines below navel ; feeling of heat in l. eye, and pricking in inner canthus , cold feeling in knees ; nausea rising up from stomach commenced again ; prickling on 1. cheek ; itching in anus ; burning itching on r. cheek, near ear ; sensation of heat in stomach ; coldness of legs ; sense of stiffness in l. knee with burning in joint ; severe fit of coughing without expectoration ; collection of water in the mouth ; pricking in 1. side of lower lip repeatedly ; pricking in orifice of urethra ; pressure in occiput ; hollow feel in stomach ; burning of skin in temple towards 1. eye ; pressure in root of noseg.; April itching6th.-In on scrotum, andto order then in concha ascertain theofeffects r. ear. of the plant when further developed, I chewed bits of leaves from plants in different habitats. The stem was beginning to grow. In regard to the taste, the following facts were established : 1. The young leaves taste more acrid than the older. 2. The plants in moist hedges have hardly any acridity, even when exposed to the sun. 3. The plants on the sunny side of a high wall immediately after chewing (at 10 a.m.) cause burning in the tongue, nausea, and a scraping sensation in the throat ; upon occurrence of which I spat out chewed leaf. In 5 m. determination of blood to head ; sense of empty hollowness in stomach, like that in bulimia, with exhaustion of strength in walking ; oppression of chest and difficult respiration ; stitch in l. kidney on taking deep breath ; pain in 1. shoulder-blade on lower angle, and in l. shoulder ; stitch in 1 . hypochondrium ; collection of water in mouth ; tensive pain in scrobiculus cordis on deep inspiration. In 4 h. tearing in forehead over r.

eye ; fit of coughing without expectoration and without any provocation ; sense of heat in bronchial tubes ; eructation ; burning in upper lip ; pain on inner side of r. knee ; itching of anus. In h. after, all sufferings ceased. h. 8th, 9 a.m., took about I dr. of milk flowing from plucked leafstalk of a strong plant on tongue. It caused burning corroding sensation on tongue, followed by nausea and sense of fulness in abdomen. In 5 m. sense of heat in teeth ; pressure like that of a ribbon on forehead and temporal region, and anterior lobes of brain, inside cranium ; stitch in border of ribs on 1. in cardiac region ; violent itching on back of r. hand near joint of 3rd finger; fit of coughing without expectoration or previous provocation. In h. itching pricking sensation in inner canthus of 1. eye ; transient tearing over 1. eyebrow, and then over r. in a diagonal direction ; pricking pain in 1. meatus auditorius ; pressure in occiput with drawing pain in occipital muscles on 1. side towards nape ; pressure in larynx ; slight pricking in tonsils during empty swallowing ; pain in spine between shoulders ; weight and pressure in brain ; eructation. In an h. after experiment no symptoms remained. i. In afternoon I tried experiments with external application. Fresh juice streaked on hand had no effect, except yellow stains very difficult to remove ; nor rubbing in tincture on hand. Upon this I rubbed 5 dr. of freshly-prepared tincture into each eye. This caused no sensation in lids. The tincture that was put between lids into eye caused burning in eye, especially in caruncula lachrymalis, and sense of heat in eye. In I m. these sensations ceased, and in their stead commenced feeling of freshness and coolness in eye. In h. I washed the yellow-stained lids (so the fears about the caustic effects on the eyes are unfounded) . The soap used for this purpose caused slight burning of outer skin of eyelids. In h. pressure on forehead and transient tearing over r. eye ; pain in 3 1. upper back teeth on chewing, and pressure also of gum on that side ; pressure between shoulderblades in spine.-9th. Pain in teeth as on previous d.; towards e. continued pains in them without being touched. A leaf bruised and laid on suffering teeth removed pains for h., after which they became very violent till bedtime, and extended to 1. ear ; cold water in mouth relieved red them .- roth . Pain in said teeth on pressure all d. On awaking pressive pain in l. upper eyelid ; conjunctiva of lower eyelid is much reddened. Heaviness and drowsiness all d.- 11th. Awoke with extraordinary perspiration and no cessation of pain in teeth ; tongue coated yellow. (Previously, when suffering from a cold, or, more rarely, from toothache in consequence of a cold, I used to get rid of it when perspiration conmenced. Therefore, in this case, I considered perspiration as well as toothache as medicinal symptoms, which, from the quickly repeated action in various ways on the 8th and 9th, were more continuous than I had intended. Besides, nothing had preceded to account for the pains in teeth, which, moreover, had constantly occurred during previous provings.) Towards e. tooth pains grew more violent (air had cooled and an icy north-wester was blowing) ; gums very painful to touch in l. upper jaw ; frequent

unusual erections ; weariness all d.; perspiration immediately on lying down. Awoke about midnight with violent pains in 1. upper jaw and corresponding molars, drawing to 1. ear and eye. Because pains hindered sleep, I got up and read till 2, when drowsiness came on and quiet sleep till about 7.- 12th, 7 a.m., awoke with toothache (weather as yesterday e.; thermometer at oº Cent.; the wind brought some flakes of snow). Tongue thickly coated yellow, with red edges, on which pressure of teeth leaves visible marks ; 1. half of face burns, and is reddened, swollen, and tense, as in erysipelas, also 1. ear. The redness ceased h. after rising. Drawing pain in 1. upper jaw, nostril, eye, ear, temple, half of nape, shoulder-blade, and ankle ; cold feel in feet, especially 1.; collection of water in mouth ; 1. upper gum and half of hard palate swollen and red ; weariness and drowsiness ; pain in palate and gum is aggravated by every movement of mouth ; pain in 1. side of throat on swallowing ; stiff neck, 1. side ; much thirst ; drawing in thorax ; no stool as usual soon after rising ; small pustules with red border on neck, shoulder, and head, all on l.; appetite unaltered ; some sleep after dinner. Awoke with confusion and heat of head ; every movement of mouth makes pain in the teeth more violent; mouth always full of stringy mucus ; pain on swallowing is less remarkable, but violent on 1. side of palate from pressure of tongue during deglutition ; tongue still thickly coated yellow ; pulse all d. about 100 ; urine not altered in quality, passed frequently from drinking much water ; no stool ; tightness of chest, as if compressed by a cuirass ; pain in 1. hollow of knee ; outside of neck on 1. and 1. cheek swollen and painful on pressure ; 1. ear as if stopped ; great languor and feebleness, so that a walk in country had to be given up. Pain injaw and mouth only permits speaking in a low voice ; tongue cannot be fully extruded, nor mouth opened as wide as usual. Looked ill ; shivering after drinking water ; eyelids fall when writing ; shivering chill for some m. on lying down in e.- 13th . General perspiration ; tongue not very thickly coated, more white than yellow. On 1. side of hard palate, near furthest molar, a whitish coloured tumour of size of bean, out of which, after puncture with lancet, some thick, yellow, inodorous and tasteless matter issued ; pains in teeth, jaws, and palate, milder than yesterday ; swelling on the neck diminished ; stool not till afternoon, very dark brown, consistence normal. At stool anus as if swollen, with pain like a wound in it afterwards.- 14th . Drawing in spermatic cords and testicles ; swelling of neck and cheek gone ; drawing pain in upperjaw towards l. eye and ear ; teeth still a little8.painful Mad. on pressure, B-, æt, 32 ;also palate when ; touched choleric-nervous hair with dark the tongue. brown ; weak muscles, tendency to leanness ; can only eat a little at a time, dislikes water and fruit, can only drink water when very thirsty, indigestible food causes acidity of stomach and loss of appetite, wine and old beer agree with her ; skin dry, very little inclined to perspire. Till puberty, scrofulous swelling of nose and upper lip, afterwards migraine and spasms of stomach. Shortly before menstruation frequent swelling of abdomen and pain in sacrum ; had six living children. Cough from taking cold ; internal organs healthy ; in perfect health at time of

proving ; mind acute with fine perception ; highly sensitive to medicine, even much diluted. a. Oct. 28th, 1861 , 10 a.m., took 30 dr. of tinct. In 10 m. unpleasant heat in pit of stomach ; jerking of fingers of 1. hand ; jerking in eyelids ; sensation of constriction in muscles of nape, as if head were drawn back. In 20 m. weight in back of head ; humming in ears, which seem as if stopped ; burning in eyes ; dryness and sense of constriction in throat, forcing her to swallow ; difficulty of swallowing ; eructation of air ; hiccup ; cramp in fingers of 1. hand ; often obliged to pass water. In nose sensation as if cold air were streaming through to throat on inspiration. In 2 h. had to pass water 6 times in quick succession, in small quantity ; tearing pains in teeth of 1. lower jaw, increased by chewing ; obliged to take deep breath for 5 m. together ; difficulty of breathing ; pain in knee-joints. She cannot extend 1. leg without violent pain in knee ; pain like a wound in knee-joints, increased by pressure ; feels as if temples were compressed. 7 p.m., tightness of chest ; pain in l. knee ; sensation as if 1. hand were swollen, benumbed (without feeling) and paralysed, as ifshe could not bend it ; amelioration by rubbing it ; several times dry short cough ; burning and redness of 1. cheek ; feet as if paralysed; pricking like needles under 1. heel ; burning in l. leg ; weight and tension of muscles of nape and occiput have gradually ceased ; articular surfaces of knee-joint painful on moving, as if injured. About II p.m. knee pains cease, but violent pains in occiput set in, with dull pressure and weight ; on lying down, she cannot raise her head, but has to lift it with her hands ; occiput painful on feeling it, as if it were broken loose from the rest of the cranium ; sensation as if head on being raised fell forwards, whilst occiput lay still, held fast by nape ; same sensation on awakening frequently in n.; otherwise, as if benumbed.-29th, a.m., feeling like a wound on under surface of 1. knee-joint ; in walking, she must put out 1. leg at full length, and, after bending knee, is obliged to extend it slowly, lest the movement should excite violent wound-like pain in joint. Sudden cessation of pains 24 h. after dose.-31st. Menstruation commenced 2 d. too soon ; increased, but without any suffering. b. Nov. 5th, 9.30 a.m., took 90 dr. In 10 m. pain in occiput more violent than in first proving ; pains in eyes, as if lids were forcibly pressed down ; short and difficult breathing, with oppression and anguish in chest ; breath hot ; mouth and lips dried. Inh. twice obliged to pass water, with cramp-like pains in urethra ; bruised feel in legs ; stumbling gait ; shivering ; unusual sense of hunger ; sudden pricking in l. eye, with feeling as if it were torn out, 5 times in succession ; feel in 1. lower teeth as if they were all loose, shaky, and too long. At noon, restlessness and agony of conscience as if she had committed a great crime and must run away, and yet could find no rest ; trembling all over body ; glowing heat all over head ; both cheeks with well-defined patch of dark red ; thirst ; pulse full, 90 ; nausea, as if fainting ; can only get into bed tottering ; violent pulsation in arteries, with violent pains all over head, from ear to ear, with dread of light ; speaking becomes difficult ; all limbs as if bruised ; heat in face lasts h.; feet icy cold ; cold shuddering, as if drenched with cold

water ; during rigor, short quick breathing ; legs as if paralysed and dead ; violent pain in all teeth in speaking, and in both jaws ; frequent yawning ; nausea on attempting to take broth for dinner, she can get nothing down ; frequent dry short cough ; provocation to cough in the larynx; frequent stitches and jumping pains in 1. temple ; looks ill and suffering ; pale sunken face ; on closing eyes, whereby pain in head is somewhat alleviated, singing and ringing in ears ; believes she cannot think, and has lost her intellect. A fit of anguish, with nausea and retching, about 3 p.m.; during anguish bright glittering specks before eyes ; she cannot clearly distinguish any object ; she gets up. About 4p.m., the tearing pains in head transversely crossing crown become intolerable, forcing tears ; from walking she is so faint as to be obliged to go to bed again ; she raises herself in agony, and tears clothes from her neck and chest ; vomits some mucus, without relief from headache, and thinks she must die ; faints for a long time ; extremities feel cold ; pulse and beating of heart imperceptible ; rubbing soles of feet restores consciousness, but she declares she does not feel the rubbing ; continuance of rubbing relieves headache ; she says it is as if all her intestines were torn out of abdomen, producing loss of senses ; attack of violent pain in sternum at each inspiration ; cold all over body ; in spite of warmed covering cannot get warm in bed ; pulse 50, the intervals not quite uniform. About 7.30 able to leave bed ; head less painful ; from time to time tearing in l. eye and temple ; can eat some bread and butter ; feels very languid and drowsy, and cannot move at all ; wishes room to be quite hot, heat is a comfort to her ; twitching in arms and legs and head on moving arm ; pain like a bruise in sacrum on moving. About 8.30 p.m. pressure on pit of stomach ; frequent waking at n.; cannot think aright on any subject ; pains in occiput ; incoherent dreams ; awaking with short cough.-6th. In m. weight in head, and, on moving, pain in lumbar vertebræ as if they were crushed. No symptoms then till 5 ; inclination for acids ; pulse 90. About 5 pains in the lumbar vertebræ become more violent, and extend forwards to chest ; trembling all over ; anguish, restlessness, oppression of chest ; clothes feel too tight on chest ; glowing heat in face ; burning in cheeks, which are coloured with dark red patches ; dryness of mouth and throat; thirst; cannot take deep breath for pains in front of chest ; at each inspiration pain inside chest, with short dry cough, which increases pains, and troubles her at short intervals ; violent pain at every breath all round lower angle of shoulder-blades. She is obliged to sit upright, and durst not move, because it makes pain in chest intolerable ; is obliged to breathe short and quick to enable her to endure chest and back pains in any measure; heat and anguish till 7 ; chest pains increase in violence till 9, after which they cease. She could take nothing at supper-time but water. About 11 a little more appetite again. All through n. awoke often from short cough, with pains in back, and strong itching in occiput.-7th. No symptoms till 2 p.m.; then pains in back and sacrum ; 4 stools in h. , pappy, with some pains in intestines. From 3 to 4 violent pains around navel ; pains again in chest on inspiration, aggravated by movement ; spasmodic pains close over pubes, with frequent urging to pass water ;

pain across above navel, as if abdomen were constricted with a string, till 6. -8th. Sound sleep all night; cannot rouse herself properly ; inclination for vinegar and sour food ; vinegar tastes less sour ; pain in r. shoulder all day, worse when moving. 9 p.m. , on getting her clothes ready for the wash, attack of faintness, with feeling of anguish in chest, trembling, and short cough ; is obliged to go to bed, and soon falls asleep.-9th, 8 a.m., continual pain in r. shoulder, more violent than yesterday; fits of anguish in e., with feeling as if perspiration were breaking out on forehead; felt quite well in open air.- roth . From 8 a.m. to 2 p.m., drawing pain in the occiput, with anguish in chest, through which appetite is gone at dinner-time, with tendency to weeping ; pains in 1. shoulder-blade and sacrum whole d. At n., frequent awaking from toothache in 1. upper jaw.- 11th. Since the proving she has never been able to recollect in m. what she has dreamt ; often awoke in n. from toothache ; hair comes off in quantities from occiput by combing.- 12th. Lower lumbar vertebra and shoulderblades painful under pressure ; pustules on r. cheek like chicken-pox ; toothache in n. as last n.-17th. Every night till to-day, toothache ; daily loss of hair from occiput; hair over r. ear matted for breadth of 4 fingers ; hair drier than usual ; pustules on bosom; pain in sacrum and headache in occiput, from morn till noon . About 3, dull pain in both jaws on 1. side, extending up towards eye close to nose, and even to temple ; throbbing pain there ; close to nose throbbing as when a gumboil is going to form (she once had agumboil on this spot) ; pain is increased by touching 1. side of face. From 6 to 8 above-mentioned pain increases to great violence (chilly weather commences with mid-day breeze) ; this pain is relieved by magnetic pass with hand ; continued chills ; often awakening in n. from these severe pains ; sound sleep from 5 a.m.-18th. About 2 p.m., pressive pain in region of liver, on edge of ribs ; pressure of clothes there causes severe pains ; much eructation ; coffee distasteful to her. About 5, same pains in teeth as yesterday ; they feel too long; painful spot on cheek appears to her swollen and gathering, though no swelling is perceptible ; pains in knee-joints, calves, and lower part of thigh, till 9 ; calves are painful when grasped ; she cannot advance her legs to walk without fatigue, and often knuckles at the knee.-19th. She awoke with strong coryza ; as she sometimes suffers in this way, it may easily be due to other influences, so that the subsequent symptoms have no longer any value. She has grown thinner during the proving. c. Dec. 3rd, 10 p.m., took 2 dr. of tinct. in half a glass of water. In 10 m. pricking pain in region of larynx, with sensation as if neck were swollen externally in region of larynx ; stitches in quick succession through larynx, externally and internally in throat ; sensation as if air could not pass owing to swelling of larynx ; dryness in throat ; the throat seems constricted ; eructation. In 5 m. more, the sudden pain in throat better ; copious discharge of water by drops from 1. nostril (less from r.), with burning of outer edge ; in h. pain in region of liver, quickly spreading downwards transversely above navel through intestines ; she feels as if on this place abdomen was constricted by a cord ; in bed, much flatus. -4th. Slept well ; urine in m. turbid

directly after passing ; stool more lax than usual ; less appetite for breakfast. About 9 a.m., two spoonfuls of mixture of 5 dr. in half a glass of water. In 5 m. pain in 1. shoulder, extendingdown to deltoid. In h . pain in lower part of thoracic wall on r., reaching to side, a hand's breadth in extent, aggravated by each inspiration ; sudden call to pass urine twice in quick succession. In h. pains of chest increasing ; pressed to pass water every h.-five times in It h. II a.m. , took a tablespoonful. In 10 m. pain in r. knee-joint, aggravated by movement. At 2 p.m., two dr. at once in water. In 10 m. pains over navel in intestines, with constriction across ; oppression in chest ; want of breath ; pressure in front of stomach ; pain, like a bruise, from r. shoulder-blade down back ; pain in last lumbar vertebra, as if broken ; tensive pain in forehead, as if from band over eyes ; pressure and pain in eyes, as if they were squeezed in, on upper part of eyeball, more in 1. than r.; she keeps her eyes closed, because of the relief it affords them ; sudden severe anguish with palpitation ofheart ; heart's beats not more frequent nor irregular, but so intensified that clothes are lifted by movement communicated to thorax, and she hears beating of heart so plain that she fancies others must hear it, for 5 m.; pain in inguinal region which prevents her from walking, about 4 o'clock. Several times persistent stitches for some m. on r. side of thorax, which compel short breathing, and are intolerable when deeper breathing is attempted; great cold in face; cheeks pale and feel quite cold for 2 h.; pulse generally 70,now 50 ; stool loose, bright yellow ; great weakness ; frequent yawning ; languor and prostration all over body ; total loss of appetite. Slept from 7 till 9 sitting on a sofa ; cessation of headache on awaking ; pressure on stomach ; oppression of chest ; in nape and shoulder-blades sensation as if bones were torn out of their place ; cold feeling all over without diminution of temperature ; frequent eructation, whereby stomach is somewhat relieved ; taste somewhat bitter ; continued dry cough in two fits in quick succession ; when coughing, pains in chest and sacrum ; pain in larynx ; pain in r. knee as if broken. At n. on awaking often confusion, and heaviness in occiput ; if she wishes to sit upright, occiput seems to be fastened on pillow. -5th. After getting up muddled and beclouded ; pain in the sacrum on moving. About 5 p.m., confusion of head and vertigo ; nausea, as if she must vomit ; palpitation of the heart, as yesterday, with anguish for some m., but not so violent ; total loss of appetite ; eructation, relieving nausea ; frequent yawning ; pain in occiput with sensation as if head were drawn backward. Since the proving she has become strikingly thinner. d. 6th. At 10 a.m. 6th dil., 20 globules at once. Inh. after pressure on bladder 3 times in h., with discharge each time ; eructation ; frequent yawning ; pain in last lumbar vertebra, alternately with pain in shoulder-blades, aggravated by movement ; loss of appetite ; pains in inguinal region, hindering walking. From 1.30 to 2.30 burning heat in l. cheek ; small circumscribed spot on 1. cheek, which in h. attained size of crown-piece, circular, dark red, and somewhat raised ; eructation all d.; great languor. 8 p.m., pains in the last lumbar vertebra ; she cannot sit straight up, as if she had no strength in sacrum ; slight pain in sacrum on bending upper part of body forwards ;

stool twice, pappy.-7th. In n. on awaking, she can with difficulty raise her head from weight in occiput ; pains in first cervical vertebra, aggravated by moving head, and by pressure. She has eaten scarcely anything for some d.; boiled food is very disagreeable to her. Pain in neck continued till 2 p.m. In m. after rising, burning in eyelids and pressive pain in eyeballs, as if they were squeezed into head, worse on 1. side ; redness and swelling of lower eyelids, and also redness of conjunctiva of lower lid. In forenoon she took nothing, at noon only two spoonfuls of soup ; tongue clean ; eructation all d. 2 p.m. , when pains in neck ceased, a red, hot, circular, somewhat prominent spot, as yesterday, on 1. cheek, lasting 2 h. In e. violent pressive pains in l. eye, in middle of ball, as if it were so large that upper eyelid could not be closed over it, alleviated by closing eyes ; conjunctiva of lower lid is reddened ; frequent weeping ; lamplight aggravates pains ; failure of appetite.- 8th. No more symptoms ; appetite better.-9th. About 10, as she was standing in dining-room, busy with jam pots, she suddenly She felt uneasiness in all limbs, compelling her to make movements. strove to stand still, but was obliged to step out, and to move arms ; she could not describe the sensation she experienced ; she had to walk up and down for a few m., and then was able to stand still again. If she were to make a comparison, she might be like one who suffered such restlessness from ennui as not to know what to do. She has not, with this, experienced any disquiet or anguish of mind. Afterwards, it was agreeable to her to be able to sit down. She had a similar attack on the 5th, p.m., whilst sewing, when she was quite well, but said nothing about it because she thought she could not describe sensation with sufficient accuracy. She had to get up quickly and walk about, whereupon she soon got rid of the restlessness in limbs.- Ioth, II a.m., took 30 globules of 6th. In 10 m. oppression of chest, with eructations, which relieve it ; heat for an h., mounting up from chest to throat as far as larynx. Inh. after dose, red spot on r. cheek ; gradually spot extends over whole cheek. On upper part of r. cheek many red pimples, somewhat raised in centre, feeling rough ; on 1. cheek, a circumscribed red spot of size of one sixth of a thaler, for 1 h.; repeated yawning ; & h. after dose, passed urine twice in quick succession, after great urging. About I p.m., anguish and strong pulsation of the heart for 10 m., obliging her to sit down while it lasted ; pains in sacrum, aggravated by moving. Towards e., pressure in region of larynx ; sensation as if throat there was swollen, so as to impede respiration ; great weariness, as if she could sleep as she sits ; sudden violent pain in knee, aggravated by treading. At 9 she went to bed, as is her custom ; awoke frequently with pain in throat, increased by swallowing ; dryness in throat ; same feeling of swelling in larynx, hindering respiration ; pain in 1. knee ; mucous discharge all d. from vagina, colouring linenyellow.-11th. In m. burning pain in l. eye on awaking, which gradually ceased after getting up ; good appetite. About 4, pain in sacrum and region of kidneys, which is very sensitive to pressure ; the pressure of tapes of body-clothes causes pain about kidneys ; urine lemon yellow, turbid ; urging pain in bladder, with spasmodic quivering pains in inguinal region ; after these pains ceased, oppression of chest.

-12th., m. , repeated urging to urinate ; spasmodic drawing in inguinal region ; turbid lemon-yellow urine. In e., clear urine ; mucous discharge from vagina. 10 p.m. , took 60 globules of 6th ; in 10 m. spasmodic pain in region of loins on lying down ; in bed, violent pain in scrobiculus cordis, as if stomach were constricted ; awaking in n. with pressure in occiput and shivering ; violent pains in uppermost cervical vertebra, aggravated by moving. From vertebra the pain extends to crown up to a spot of size of a pea, in which violent jerking and pricking is felt ; occiput heavy, as if it could not be raised from pillow ; stupefaction ; pain in region ofkidneys ; mucous discharge from vagina all d.- 13th. From pain in region of kidneys she could not lie on her back, and was also obliged to change sides often, finding most relief from lying on abdomen. In m. on rising, violent shooting in region ofkidneys, compelling her to cry aloud, and causing her to crouch down ; in the room, anguish, trembling, vertigo, heat in the head, she must go into open air, where she gets better ; suffering, pale face ; head symptoms still continue as in n.; jerking and pricking on little spot on crown worse, cannot touch it without exciting violent pain there ; disquiet of mind, wishing to die ; shooting in lumbar region, increased by walking, especially in 1. side, better towards noon. In afternoon, periodic urging and pressure on rectum, as if she must go to stool, without any result ; heat all over face ; cheeks red and burning. Towards e. great drowsiness, her eyes closing as she sits ; if awakened, she falls fast asleep again ; trembling in wrists and fingers.- 14th. Had dreamt about a journey in long detail, and could remember most minute circumstances on awaking ; chill and shivering in n. on awaking, with heaviness and trembling in knees. Forenoon, trembling in knees ; heaviness in knees and legs, as if she could not step out ; stool very hard and difficult, with pain in rectum. About 4, heat in both cheeks for h. At 6, shivering chill for h., with shuddering chattering of teeth as if icy-cold water were poured all over body ; then great heat, especially all over head ; heat in cheeks ; face red and swollen ; thirst forh.; pulse 90 ; then oppression of chest ; difficulty of breathing ; violent shooting pains in region of kidneys, increased by moving ; bruised pain in thighs, extending to calves, aggravated by walking and by touch ; heaviness in legs, as if she had to drag a great weight at each step. E., cutting pain in urethra on passing urine, still continuing afterwards ; hands burning hot, swollen half way up forearm ; she cannot keep her shoes on, because they seem to be too tight, though they are very wide ; great tension in lower part of legs.- 15th. In n. frequent awaking from tensive pain in thighs, two hands' breadth, midway between hip andknee ; stiffness in knee-joint ; paralytic drawing in knee-, wrist-, and ankle-joints ; pain when touched in legs and forearm. In m. r. arm as if paralysed, with sensation of numbness and cold ; the temperature actually lower than in l. arm, relieved by rubbing ; good appetite at noon. From 2 to 6 p.m., violent pricking in r. side of chest ; she has to draw her breath slowly and cautiously on account of the pain ; can only speak softly ; sometimes is only easy when she does not move or speak ; has to pull off shoes and loosen garters ; swelling of legs ; visible cæde

matous swelling about ankles, also in calves ; hands and forearms ædematous, still more swollen than d. before. She dreads becoming dropsical, because her legs again seem so swollen and heavy. Feeling of swelling in the thighs, two hands' breadth in extent, midway between hip and knee. In e., good appetite ; & h. before supper, rigor for some m.- 16th. Good sleep in n., with gentle general perspiration. In m., no more swelling in arms and legs ; p.m., shooting jerking pains somewhat to r., from lower part of sternum right through to back, aggravated by movement and inspiration ; pressive pain in head ; in highest cervical vertebræ pain on turning head ; increased pain in chest from bending trunk forwards, and in back from bending backwards ; frequent eructations, whereby pains in chest are relieved ; indisposition to move ; pale face. About 8 p.m., when sitting on sofa, had to rise suddenly and walk about ; could not for the world sit still ; involuntarily grasps forearms with hands, squeezes hands together, and during fit cannot prevail upon herself to speak of her condition ; after a few m., during which she walks about room, she is able to sit down again. During this muscular restlessness she felt no pains in chest and head ; afterwards pains set in again. At first she tried to remain sitting, but her feet would rise up in spite of her.-17th. Slept well till 4; awoke with pain in r. shoulder-blade, worse on inspiration or by moving r. arm ; pains spread, after rising on r. side, round to chest, which is oppressed in consequence. After dinner, cessation of pains till 2 p.m., then they were more violent till e.-18th . After going to bed last n. she was seized with violent pain in r. shoulder-joint, whither pains suddenly withdrew from shoulder-blade ; if she tries to move her arm she cannot, because then it feels as if broken ; r. arm is then quite cold and stiff; pains extend from shoulder to wrist. In course of forenoon, pains gradually cease. On rising, vertigo, nausea, and watering of the mouth. About 9 a.m., burning over eyebrow towards the temple, and then over forehead up to crown, with pressure deep into brain, getting worse towards e. About 8 p.m. , sudden cessation of head pains, and sudden violent pain in r. side in region of 7th and 8th ribs, increased by inspiration and movement for 2 h. With that, renewed pressure on brain. At n., awoke with violent pains in l. lumbar region, and no headache.-19th. Towards e., pressure on scrobiculus cordis, with oppression of chest and difficulty of breathing ; 7th and 8th ribs on both sides painful to touch, and at every inspiration as if wounded, worse on r., and lasted there longer ; cold sensation spreads from spine out to these ribs, and on in front to sternum, more on r. than 1.; frequent yawning and eructation ; tensive, spasmodic pain, spreading from above and outside downwards and inwards on both sides, in inguinal region ; lemon-yellow urine, turbid immediately after passing.-20th. Urine of yesterday e. still turbid, with mucous greyish-yellow cloudy sediment ; inner surface of vessel, as far as urine reached, is covered with reddish-yellow crystals of uric acid. Urine of this m. is again turbid when newly passed, as yesterday ; towards noon it has again a greyish-yellow cloud at bottom, and uric acid precipitated, as in m.; urine passed shortly before dinner is less turbid, that in afternoon is clear ; both ribs are still

painful to touch in m. and all d., worse p.m., when the cold feel and pressure on scrobiculus cordis again set in, with difficulty of breathing. Better towards e.; sorrowful disposition ; she fears she has ruined her health by the proving.- 21st, e., after II p.m., periodic palpitation ; drawing forcing pains in inguinal region ; pressure and oppression on chest ; exhaustion ; emaciation ; clothes that were tight before proving are now slack ; cannot use her thimble because it drops off.-22nd . No symptoms ; appetite better.- 23rd, afternoon, little yellow burning vesicles on r. ala nasi and 1. under lip. -24th. Little yellow scabs where vesicles were ; burning sensation here and there on face, as if there were similar vesicles there ; appetite good.-28th. No symptoms up to this date ; appetite good as before the proving ; she no longer looks pale and invalided. All through January no suffering. e.-Feb. 8th. At I p.m., an h. after eating, took 5 dr. of tinct.; forth. a feeling of cord about forehead and temples, close over brows, as if head were compressed by it ; vertigo and dizziness in head ; trembling in all limbs ; heat in face, with red cheeks, alternating with shivering ; water flows from each nostril ; blackness before eyes, with sensation as if she were fainting ; drowsiness and languor all over body, obliging her to sit down ; inclination to sleep, with great weariness ; frequent yawning and continued eructation. In 1 h. later, pain over navel, as if abdomen were constricted by a string, for h.; then griping in intestines, followed by six watery stools in 1 h.; after each evacuation spasmodic constriction of anus. 4 p.m., every 5 m. repeated jerking pains on 1. zygoma, as if lacerated ; cramp in calves, with heaviness in legs, as if weights were hung upon them ; pain in r. knee ; utter loss of appetite till 4 p.m.; repeated urging and discharge of urine ; pain in l. shoulder and shoulder-blade, aggravated by moving arın. In e., burning as if from nettles in whole face except forehead. At n. frequent griping, with much discharge of flatus.-9th. In m. bright red spots of size of lentil, confluent, with papule in centre of each, all over face except forehead ; rough to touch ; burning. Three times in h. thin pappy stools preceded by nipping pains in intestines ; pain like a wound in all vertebræ, aggravated by movement ; and pressure on spinous processes. About 2 p.m. chill, as if drenched with cold water, intermitting with dry heat, especially in face, with feet constantly cold ; great weariness and paralytic sensation in limbs. During hot fit she falls asleep in sitting posture, and cold fit awakes her (2 h. long). In e. in bed she cannot go to sleep for feeling of numbness of lower extremities from cold, though bed had been warmed. In n. dreams of corpses . Towards e. she lost eruption on face. 10th, m., feeling of constriction across navel ; sensation of twisting and movement in abdomen above navel as if an animal were wriggling all through intestines. Stool thin, pappy, bright yellow, three times in 1 h. 2 p.m., violent stitches in lower part of thorax on r. on inspiring, aggravated by movement and coughing ; drawing pains from lower side of sternum on r. as far as spine ; pain like a wound in lower ribs on r.; frequent fits of short dry cough ; difficulty of breathing, cannot take a deep breath for stitches ; wound-like pain in lower r. half of thorax, so that mere contact of clothes increases it ; collection of water in mouth. VOL . II . 6

Towards e. cold feet ; cold feeling in lower extremities. Skin all over body feels cool to touch, though room is very warm.- 11th. All forenoon urging to stool every ½ h., with griping in intestines and constriction in rectum without evacuation. In e. evacuation normal. Towards e. collection of water in mouth ; menstruation commenced following n. in excess, but without any suffering.- 12th. Ribs on r. side still painful to touch, as if raw ; vertigo, especially on closing eyes, as if everything whirled in a circle.-13th. Confusion of head, with a sensation of cord about forehead; pains in lumbar vertebræ like a wound ; spasmodic pain in r. kidney and liver all d., worse from 4 p.m. till about 9, with perspiration on forehead and hands ; wound-like pain in lower ribs and r. side ; collection of water in mouth ; increased thirst ; burning in eyes. 4 p.m., chill for h., then heat, especially in head, with cold in legs for 2 h. Great languor ; overcome by slight exertion ; diminished appetite.-14th, 15th. As 13th.-16th. The same till 4 p.m.; then chill for few m. only, with heat which lasted only h., then felt quite well.-17th. About 9 a.m. sensation in forehead and temples as of cord till noon ; same sensation about 7 p.m.; trembling, as if she would fall forwards, without vertigo. Muddled head ; trembling in upper extremities ; sensation of icy cold in calves and soles ; the legs feel cool.-18th. An h. after rising, feeling of hoop about forehead and temples ; inclination to close eyes ; difficulty of opening lids, as if upper lids were drawn down again, till noon. Towards e. return of sufferings in higher degree ; feet cold.- 19th . As before ; menstruation has passed unnoticed into leucorrhœa ; secretion is viscid, mucous, and stains linen yellow. (Thirteen years previously, when unmarried, she suffered in same way.) No appetite in e. for 6 d. Frequent urging to pass urine, which goes off without actual discharge.- 20th. Frontal headache as before, from getting up till mid-day ; leucorrhea abundant all d. Towards e. pain like a wound in lumbar vertebræ and five lower dorsal, aggravated by pressure with hand, and by every movement ; also in five lower ribs on r.; pain in r. renal region, as previously. 21st. (South wind ; afternoon, thick fog ; barometer low.) In m. on rising, frontal headache as before, relieved by closing eyes. About 2 flying heats in face ; anguish obliging her to loosen dress on chest for h .; pains in both kidneys as before ; violent pains in same vertebræ and ribs as yesterday ; ribs as if ulcerated ; abundant leucorrhea. She cannot take a deep breath because it increases pain ; heaviness and stiffness in legs ; drawing spasmodic pain from above downwards, and in iliac and inguinal region towards pubes. No appetite all d.-22nd. In m. no more leucorrhœa ; urine reddish, turbid in h. In 2 h. reddish flocculent loose sediment ; after standing till e. supernatant urine not yet quite clear. Same drawing spasmodic pains as yesterday, preventing walking. From increase of these pains, r. leg can with difficulty be raised ; ankles painful, especially after walking, as if sprained. E., good appetite ; pains as before in vertebræ all d.-23rd. From 9 to 11 wound-like pain in same vertebræ ; pain in r. kidney. Towards 5 p.m. pain in forehead as before, till bedtime ; wound-like pain as before in r. ribs ; pain like dislocation in ankles all d., more violent in n. Directly after supper, sudden

cessation of pains in ribs ; increased thirst.-24th. From 9 to II pain in forehead as before ; dislocation pain in r. ankle, less in l., till 5 ; from 5 and afterwards, paralytic feeling, stiffness and coldness in r. thigh and leg ; vertebræ only painful on pressure and movement. For a week past, temper much excited ; daily outbreak of anger without provocation. She could beat the children, and trembles with rage at having no occasion to do so.-25th, a.m., urine clear, dark yellow. 2 p.m., urine, when passed, turbid, dark brownish red, like porter, forming bubbles round edge. (It was thrown away through carelessness, so that no examination could be made.) At next discharge, towards e. , it was normal. Shortly before turbid urine passed, feeling of constriction in hypogastrium ; no other suffering all d. f. March 14th. Since Feb. 25th till to-day, daily itching in anus and rectum . 10 a.m. , chewed a leaflet of C. and swallowed juice. In 10 m. fluent coryza, and sense of swelling in larynx till noon. In afternoon violent itching in rectum as usual.- 15th. In m. sensation as if rectum were forced out, with spasmodic constriction of anus and rectum all d. Stool causes pains in anus.- 16th, m., hard stool with great pain ; burning and cutting in rectum and constriction of anus, alternating with itching in anus ; vertigo with faintness ; no appetite . Cannot lie on back, nor sit up, from wound-like pain in anus. An external tubercle on rectum of four millimètres diameter ; alleviation of pains by standing in bent posture.-17th. Tubercle has become larger; mucous secretion from anus, not followed by evacuation. Other sufferings as yesterday.- 18th . Same sufferings, and continual painful urging to stool without result. E., at 10, took a dose of nux vomica 6.- 19th. In m., hard stool ; later in d. soft ; pains in anus and rectum have ceased . Tubercle has diminished in course of d . -20th, m., normal stool ; pains in rectum trifing. Tubercle has shrunk ; appetite recommencing. -April 20th. Since March 14th skin, especially of face, gradually darkened as if sunburnt. Stools have continued of usual colour.-May Ist. Colour of the skin gradually disappearing up to this d. N.B.-The prover has never suffered from hæmorrhoidal symptoms, and has never had her face tanned except during pregnancy. (Ibid , 106. ) 9. Adolph B-, æt. 7, the strongest built of 6 children ; easily hurt and tearful ; good appetite. Nine months ago suffered from pleurisy of r. side with considerable fibrinous adhesion of lung to rib, which, however, is perfectly absorbed. Quite healthy now.-Nov. 4th . At 11 a.m. took tablespoonful of a solution of 10 dr. of tinct. in a tumbler of water. His sister, 2 years older, and brother 1 year younger, had manifested no symptoms after similar dose. In 5 m. pain close to navel on 1. side ; pressure first in r. then in l. eye ; nausea ; dryness at back of pharynx and palate ; pain behind r. ear ; tearing pain in r. temple, aggravated by touch. No suffering after dinner. At 2 p.m. took 2 dr. at once in water. In 5 m. nausea ; pains over navel somewhat to 1.; shooting in throat ; dizziness in head ; pain in head over each ear, worse on r. side ; tearing in r. temple and eye, afterwards in 1. eye, reaching to temple; pain in r. side of thorax, then in l.; respiration became difficult ; short fit of

coughing.-5th. At II 2 dr. at once in water. In h. heat in head with pains ; dryness of mouth ; vertigo as ifhe had been spinning round several times rapidly ; stitch in r. side. The symptoms soon pass off. At 7 p.m. 4 dr. at once in water ; vertigo soon after, with heat in head ; tearing in nostrils, especially 1.; tearing in l. eye'; pressure in throat under chin as if compressed ; tearing in temples ; nausea as if he must vomit, relieved by eructation ; yawning ; pain in forehead ; pressure in r. shoulder on moving arm ; pain under knee on walking ; pricking in l. ear, rendering it difficult to hear; tearing behind r. ear. (Ibid., 132.) 10. Reinhard B-, 9 months old, golden hair, appetite good, bowels regular and natural, in good flesh. His incisors are through his gums, previous to which he had suffered from diarrhea and whooping-cough . Towards e., occasional attacks of the latter complaint still, otherwise quite healthy. On Dec. 6th at 10 a.m., administered 10 globules of 6th. At 2 p.m. there appeared on his r. cheek a burning, dark red, round spot, which gradually increased till 5. Redness, heat, and swelling of scrotum. He screamed the whole n., especially on being touched ; heat and perspiration on his forehead.- 7th, m., both eyes were glued together with dry mucus, 1. especially. Redness and heat of scrotum. Here and there, on both sides, epidermis of scrotum was raised with flat vesicles, filled with yellow fluid, from size of pin's head to that of lentil these were painful to touch ; thin watery stool of dark yellow colour as before ; he cries if l. leg is moved, or 1. side touched. From 2 till 6 p.m. a similar gradually increasing spot on 1. cheek; towards e. vesicles on scrotum burst, and red and slightly tumid skin, denuded of epidermis, discharges a little moisture. In e. another dark yellow watery stool; sleepless whole d.; will neither sit nor lie, and must be carried about continually ; made water 5 times through d., attended with much effort, groaning, and holding of breath, -this till e.-8th. Slept better through n.; the l. eye is closed with dry mucus ; scrotum is covered with dry, red, cracked, thin scabs ; pimple similar to cow-pox, with red margin, on r. buttock; near corner of mouth, on r. cheek, small vesicle with red margin; napkin stained with reddish-brown urine, which became darker when dry ; slept from 1 till 6 p.m., and from 7.30 till5 in m.; he slept only h. in afternoon, then from 8 till 10 in e.; took some milk at 10, and then slept till 5 next m.; stool as usual.-9th. In m. a little dry mucus in 1. eye ; skin of scrotum natural ; yellow scab with red margin on pustule. -10th . 10 globules of 6th, at II a.m. At end of h . redness on 1. cheek, changing by degrees from bright to dark red ; accelerated breathing, with five eructations ; after which breathing became easier. A small pimple with red margin in same place (near mouth) as on 8th ; margin round small scabs on buttock is again apparent, and becomes dark red ; urine 3 times in h. After an h. redness on cheek disappeared ; frequent yawning; eructations frequent till e.; after coughing, curdled milk was vomited, which had not occurred before ; sleep as usual.- 11th. Cried frequently in n. without awaking ; increased warmth over whole body ; perspiration on forehead; first motion of bowels after taking last dose occurred this m.; generally his bowels are

moved at n.; consistency of stool natural ; colour lighter ; urine coloured napkin a reddish yellow ; dry lumps of mucus on r. eyelid ; red round spot on 1. cheek.-12th. Quiet sleep ; napkin coloured reddish by urine ; stool brighter coloured than usual ; both eyes closed with dry mucus; on awaking, fretful; red spots alternately on both cheeks ; red pimples here and there on cheeks ; much thick mucus discharged from nose ; urine of darker yellow than usual.- 13th . Frequent screaming in n., increased on being taken up ; eyelids glued together in m.-14th. All over r. cheek numerous red round spots, with pointed pimple in the centre ; eyelids glued together in m. by dry mucus . (Ibid., 139.) 11. Minna Kranke, æt. 20, was scrofulous in childhood, muscular system weak, has pains in limbs after bodily exertion, light hair, pale countenance, phlegmatic temperament ; she has suffered at times from pains in her l. side, also from palpitation of the heart after exerting herself ; menstruation natural ; healthy at time of experiment. Nov. 25th, 1861.-60 dr. of tinct. at 10 a.m.; after h ., feeling of heat throughout body ; oppression and pressure in l. side ; difficulty of breathing ; palpitations of heart ; twitchings in r. arm ; feeling as if something solid were rising in throat, necessitating effort to swallow, after which it seemed to descend ; twitches in knees ; dragging pain in 1. shoulder-blade and neck ; squeezing pain in the regio iliaca sinistra ; twitches in calves of legs ; ringing and tingling in ears ; dryness and heat in mouth ; thirst. Towards e. pains disappeared.-26th. 90 dr. at 9 a.m.; in h. oppressive pain and burning between cardiac region and navel, as well as in sternum ; pain in nape of neck and back of head ; tearing pain in forehead over 1. eye, in eye and eyelid, extending towards upper part of nose ; drawing pains between shoulder-blades, extending to loins ; shortness of breathing and oppression as if breast were tied together and she could not breathe ; shivering, and feeling of coldness over whole body till mid-day ; towards e. pressing pain in forehead and back of head ; alternations of heat and cold with thirst for Broihan (a kind of light effervescing beer made without hops) ; burning urine, with frequent urging to pass it ; palpitation of heart ; is unable to go to sleep at once, on account of drawing sensation in back, and headache.-27th. Awoke shortly after 4 with drawing in back, and headache ; arms as if paralysed, thrilling in them ; shortness of breath, short cough, anxiety, nausea ; pricking and ringing in l. ear ; in something less than an h. she fell asleep again tillpast 6. Afterget- " ting up, weakness in limbs ; great weariness ; depressed spirits ; pains in knees and drawing pains in calves ; in e., anxiety ; tearing pain in head, over r. ear ; face hot; throat, tongue, and lips dry ; dreamt much in n., 1

but has no recollection of subjects of dreams.-28th. Awoke after 4 with anxiety; stitches in 1. side ; oppression of chest ; cannot draw long ч.

breath on account of stitches ; oppressive headache in forehead and occiput ; face hot ; gentle perspiration ; no thirst ; soon fell asleep again till past 6; after rising, headache, anxiety ; paralysed feeling in arms and legs.12. (Ibid. L-,, man 140.)of45, sanguine temperament, pale countenance, light hair. Suffers occasionally at changes of weather from debility ; eats

sparingly, drinks no fermented liquors ; bowels regular ; perfectly well at time of experiment.- Nov. 14th. 90 dr. at 9 a.m.; after h . , dizziness , feeling of heat running over whole body, pain in nape ofneck. At end of an h. pains in temples ; particularly much dragging pain, so that whole head is affected ; nausea, as if he would vomit, but relieved by eructations ; uneasiness in chest ; dizziness again becomes stronger ; much anxiety ; oppression of stomach ; much eructation, after which a rigor makes its appearance. At 10.30, hollow rumbling in the abdomen ; drawing towards rectum ; mouth is quite dry, so that tongue almost cleaves to palate ; renewed pressure in front of stomach ; renewed feeling of heat over whole body; pains in front of neck which extend towards temples ; from II till 1, horripilation through loins ; renewed drawing in temples ; renewed nausea, which is again relieved by repeated eructations ; lassitude and paralysed feeling of limbs ; renewed nausea, eructations, shiverings in back, and much heat in head ; drawing in legs, back, and temples ; much anxiety and constriction of chest ; pressure in stomach, and nausea, which is again relieved by numerous eructations. At 7 p.m., cutting in bowels, so severe that whole body seemed drawn together ; urgent desire to stool ; three watery motions in quick succession, after which cutting abated in about 1 h.; whole e. great discharge of wind. (Ibid., 141. ) 13. Pastor G-, æt. 52, of sanguineo-phlegmatic temperament ; suffered in youth from ischias nervosa, for which he was treated with mercury in many forms. From effects of this medicine lost his hair from forehead and crown of head, and never recovered it. Subsequently suffered from bloody piles ; is sensible of changes of weather, and suffers, on taking cold, from cough and slight rheumatic pains. Appetite and digestion good. At the time free from all complaints. On Jan. 6th, at 9 a.m., took 20 dr. of tinct. Soon after, strong discharges of wind, both upwards and downwards ; urging sensations in rectum ; uncomfortable feeling in bowels, as when one has had an evacuation after taking a purgative ; metallic sourish taste on the tongue ; unpleasant smell in nose like that of black soft soap ; eructations till bedtime.- 7th, 9 a.m., 30 dr. Immediately afterwards strong discharges of wind upwards and downwards ; secretion of thin mucus in throat ; increased appetite ; motion of bowels delayed and confined. In afternoon oppression and coldness in abdomen, which was not removed by a warm blanket ; coldness over whole body, especially close under umbilical region ; drawing pain in r. side, from above downwards.-8th, 8 a.m., 40 dr. Eructations and discharges of wind ; greater appetite ; increased secretion of mucus from throat. Natural motion of bowels, but feeling accompanied the operation as if anus were constricted, and only permitted fæces to pass with difficulty ; later, another stool, soft and brighter coloured ; acid taste on tongue . Towards e. drawing and pressure between shoulders, especially in r. scapula, and towards r. side; feeling as if larynx were swollen, especially on r. side. -9th, 8 a.m., 50 dr. Increased expectoration of mucus, and now and then running at nose ; eructations ; much mucus in mouth ; p.m., drawing between shoulders ; stronger stream of urine ; p.m. and e. shuddering thrill from nape to back downwards ; unusual feeling of chill in bowels

after drinking some water ; cramp in r. calf; no motion of bowels throughout d.- 10th. No dose taken for fear of constipation. Evacuation of bowels ; traces of blood on wiping anus; appetite not so good in m. as on d. before.-11th, about 9 a.m., 10 dr. Immediately eructations ; increased expectoration of mucus ; fluent coryza ; feeling ofchill in body on drinking water, not usual ; great discharge of wind ; watery eyes ; confusion of head ; motion of bowels lighter coloured than usual ; cold shudders between shoulders ; uncomfortable feeling throughout body; vertigo ; evacuation of light colour and pappy consistency, followed by improvement in condition.-12th, 9 a.m., 5 dr. Repetition ofyesterday's symptoms, but less severe. At mid-day 5 dr. more ; feeling of great discomfort in belly with pains, relieved by a glass of wine ; confusion of head again supervened ; pressure on eyelids ; cold feet, distension and uneasiness of body, notwithstanding frequent eructations ; lassitude, without ability to sleep ; later, hot burning feet ; next m. scanty stool with itching of anus.-13th. No dose. Stool lighter coloured than usual.- 14th, 1 p.m., 2 dr. Immediately after, eructations of wind ; pains in nape ; expectoration of mucus ; pressure in fore and back parts of head ; horripilation in back ; stiffness of neck on 1. side ; pain in r. shoulder, in muscles of r. side of neck, and in region of r. clavicle ; fluent coryza ; coldness of belly ; shivering ; next m. soft, bright-coloured stool. (Ibid., 147.) 14. Pastor H-, æt. 52, choleric, sallow, pale complexion, black hair; inclined to rheum and catarrh of stomach on catching cold ; well-developed muscular system; good appetite; regular alvine discharges ; liver spots on the skin.-Nov. 25th, 10a.m., took 90 dr. tinct. In 10 m. head confused; dull; pressure in nape; secretion of thin mucus from throat and nose; water in mouth; oppression in stomach, relieved by eructations ; feeling of heat throughout body, especially in face and hands. Towards e., dull pain in head, with shivering ; scraping in throat, with water in mouth ; stitches in region of stomach; drawings in loins. -26th. Vertigo ; scraping in throat and watery discharge from nose; increased appetite in m. and mid-day (which continued for several weeks) ; several thin liquid stools daily (for 8 d. ) ; small vesicles on lips and alæ nasi (subsequently forming scabs) ; dull pressure in ears ; itching of anus (continuing for some d., occasionally felt before) ; pressure on bladder, and frequent discharges of urine ; frequent erections, even in d.; good spirits ; more inclination to speak much in company. The following d. all these symptoms gradually became weaker, and appetite stronger. Irritability of bladder and greater cheerfulness continued for 3 weeks after taking dose. (Ibid., 156.) 15. a. Miss Augusta H-, æt. 50; sanguine temperament, light hair; suffered two years previously from scarlatina, and this year from measles ; bowels regular ; pale complexion ; weak muscles ; inclined to thinness; perspires easily ; skin moist every morning on awaking; great liability to take cold, on such occasions coryza and cough; appetite good. -Nov. 25th, 8 a.m., took 90 dr. tinct. After a few m. it was evident by the excitement of her manner, that a condition resembling intoxication had set in. She felt her head giddy and confused; pressure in

nape ; pain in ears ; dryness in throat and mouth. In the course of an h. she felt as if sand were in her eyes; not so perceptible when she shut her eyes. Pressure and nausea in stomach, relieved by eructations ; drawing pains from nape down to back ; lameness of arms ; head hot ; towards e. symptoms disappeared. Two thin pappy stools.-28th, 8 a.m., 10 dr. in a glass of water, dessert-spoonful every 2 h. After a few m. head became confused; pressure in crown; scintillations before eyes. She feels as if sand were in her eyes ; pressure in nape ; shooting pains in throat, in region of larynx; a little hoarseness, with pain in breast behind sternum, especially perceptible on holding in breath ; nausea, relieved by eructations ; dryness in throat and tongue ; oppression in front part of stomach ; three thin pappy stools. On 2nd d. the C. was administered as before, followed by similar symptoms . Pressure on the stomach is stronger, for which reason she took nothing on the following d. for fear it might do her harm. On the 3rd d. no symptoms remained ; sleep and appetite both good. b. Dec. 3rd. 5 dr. tinct. in water, taken by degrees in course of d.; towards e. pressive headache.-4th . IO dr. in same manner. Severe headache on rising from bed, alleviated after breakfast. h. afterwards cerebral oppression returned ; heat in head; shootings in ears ; unpleasant burning in throat ; vertigo; nausea. Towards e. , pressive headache; scintillations before eyes.-5th. 15 dr. in same manner. She had no leisure to watch the symptoms thoroughly, but the following were strongly felt: pain in r. knee; cold feet; drawings in back; shootings in ears ; drawing in teeth. -6th . 20 dr. in same manner. After Ist dose, early in m., stupid feeling; heaviness in nape; frequent diarrhæœa ; burning in throat; great thirst; good sleep at n. On awaking, general and increased warmth, with profuse perspiration; dryness in nose ; weight over eyelids ; red pimples on chin ; head confused; drawing in back ; pain in stomach, with eructations; noises in ears, and scintillations in eyes.-7th . 25 dr. in same manner. Drawing pains in teeth ; pain in sacrum and abdomen, with frequent urgent desire to make water ; smell of urine pungent and acid; shootings in ears ; burning pain in larynx ; cough, with some expectoration of mucus ; nose stuffed; drawing in calves ; pain in r. knee; headache; pressure and scintillations of eyes ; loose motion 3 times ; pressure in nape. On awaking in m. rigor, with cold feet; point of nose swollen and red ; painful pressure on bladder.-8th . Medicine is discontinued ; symptoms as on preceding d., but weaker.-9th. Few symptoms observable ; constantly increasing appetite. (Ibid., 157.) 16. Innkeeper K-, æt. 40, never ill before; drinks no fermented liquor, as it disagrees with him; light hair, slender figure, sanguine temperament. a. [Of this proving daily notes are stated to have been lost; consequently no reliance can be placed on the report of symptoms which he has drawn up. I (Buchmann) will therefore merely relate the symptoms which he specified at certain visits I paid him during the proving, and those which I myself observed.]-Dec. 7th. Took 5 dr. Five m. after taking dose bowels were moved, which operation had habitually taken place at 9 o'clock or later. After 3 or 4 h., pricking and burning in

1. side of chest, extending upwards to back, and wakening him from sleep on following n. Some d. later, after he had increased dose to 12 dr. , he felt great weariness in all his limbs, sleeplessness, ill-humour at every trifle, irritability, and peevishness. Having made a journey, he recommenced the experiments with a daily dose of 12 dr., consequent on which an eruption broke out on alæ nasi, with red pimples here and there, yellowness of complexion of face, neck, and breast, which symptoms continued for upwards of 8 d. White of eyes also became of a dirty yellow, and edges of lids were much inflamed. [I myself observed these objective symptoms when paying him a visit for the purpose of directing the experiment.] Subsequently he increased the dose to 20 dr., and observed that this was followed by bright specks before eyes ; transient dimness of vision, so that in reading everything was dark before him; pains in making water, and afterwards pain in urethra, and drawing in l. testicle. This last symptom induced him to suspend the experiment, as he had formerly suffered from hydrocele on 1. side, brought on by contusion, and then experienced same sensations as now, which made him apprehensive of return of complaint should he continue the doses. After leaving off drug, all symptoms speedily disappeared. b. May 4th, 7 p.m., took 15 dr. Since last experiment had not observed any symptoms about him. Three m. after taking dose, a thin stool ; gripings in abdomen ; up to II p.m., four thin, yellow, slimy stools, with some discharge of blood at last.-5th, 7 a.m., 15 dr. In 15 m. afterwards pains in back, and drawing in all the body, which continued for 3 h., and gradually became easier towards mid-day. In forenoon three thick, pappy stools. At 11.30 drawing in l. testicle, accompanied with pain. Temper peevish and morose. 12 a.m. , 15 dr. At dinner ate lentils with sour sauce, and felt no symptoms p.m., except a remarkably quarrelsome temper. 8 p.m., 20 dr. At 9 pappy stool ; afterwards griping pain in abdomen, which extended to back and chest, but subsequently disappeared after discharge of fœtid flatus ; quiet sleep.-6th . Nothing taken ; no symptom.-7th, 8 a.m., 15 dr. After I h. usual stool, mixed with a little blood. After 2 h. nausea, with inclination to vomit. 12 m., 20 dr. Immediately after dose heat in face and burning in back, continuing for 2 h. Motion of bowels natural ; nausea. 8 p.m. , 20 dr. Severe nausea immediately after dose. After an h. a little vomiting of tenacious mucus. From 8th to 15th took no dose, as he was much out of sorts, and constantly trying to quarrel with his neighbours.- 15th, 6 a.m., 20 dr. Heat in face followed immediately after dose, and continued for 5 h. 1 p.m. , 25 dr. Stool followed immediately ; repeated three times within an h.; watery. In afternoon large pustules on forehead ; at same time observed a yellowness about face, the whites of eyes, and hands. Scintillations before eyes, which rendered vision uncertain. Took no dose in e., as he was afraid of an attack of weak eyes.-20th. The pustules disappeared within 4 d.; also yellow tinge of skin and eyes .-25th, 5 a.m., 30 dr.; in h. violent pains in head, with throbbing in both temples for 2 h.; then flashes before eyes for 3 h ., followed after their cessation by diarrheic stool. 1 p.m., 3 dr.; in 1

h. after anxiety, lasting till e. Drinking water causes weight and pressure on stomach ; seltzer water does not cause flatulence. Uneasy sleep, with dreams of death and a funeral and wedding.-26th. I have taken no more, on account of fluent coryza.- 28th, 7 a.m., 30 dr.; soon afterwards great hunger, which can hardly be appeased. Three pappy stools before 12. Oppression of chest, ceasing gradually at 12. 10p.m., 12 dr.; immediately after, drawing in calves and knees, up to thighs. Very restless sleep ; lassitude next m. -29th, 8 a.m., 12 dr.; in 1 h. oppression of chest for 3 h.; drawing in r. shoulder ; itching of skin. At noon to dr. At I great weariness and sleepiness ; at 5 chilliness . 10 p.m. , 10 dr.; continued chill ; weariness ; restless sleep. At 4 next m. awoke with gentle perspiration.-30th, 9 a.m., 10 dr.; in I h. great anguish, and jerking in all limbs ; burning in soles. At noon 10 dr. No symptoms but chill, which he ascribes to the circumstance of having, against orders, eaten salad. 9 p.m., 9 dr.; in 1 h . nausea, which went off on lying down ; quiet sleep ; about 4, awoke with gentle perspiration. On account of various hindrances, had to give up the proving for the present. c. July 2nd, 7 a.m., 2 dr. in a cup of water ; in 1 h. pain in upper part of chest ; stiffness of neck, especially in nape. In 4 h., violent beating in both temples. In 6 h., drawing and tearing from knees down to feet. I p.m., same dose. In 1 h. pain in 1. shoulder ; in 3 h. drawing in l. testicle, up to hip, for 1 h. 8 p.m., 3 dr. Before 12, restless sleep ; at 5, awoke in perspiration.-3rd, 7 a.m., 3 dr. At 8, burning in palms ; angry irritability ; capriciousness ; terror at least noise, as when one has not a good conscience, and cannot but feel alarmed. At noon 3 dr. In 3 h., heat in face ; stiffness in nape ; burning in urethra ; anxiety at every little noise. 10 p.m. , 3 dr. Restless sleep ; dreams about enlisting in army, with great misery, so that my wife was induced by my crying to awaken me.-4th. Took nothing, because in m. was troubled with anxiety and beating in temples.-7th, 7 a.m., 4 dr. In 1 h., pain in back, on rising from stooping posture ; drawing in legs, from knees to great toe ; in 3 h., weariness and paralytic feeling in thighs. At noon, 4 dr. In h. , great weariness ; pains in intestines ; drawing upwards to chest for 2 h., then rumbling, with discharge of flatus ; chill about 6. 8 p.m. , 4 dr. In 1 h., violent chill, so that I had to light fire to warm myself. -8th, 6 a.m., 4 dr. In 2 h. heat and redness of cheeks for 1 h.; then shivering and stitch in r. side of chest for 2 h .; burning in urethra on passing urine. At noon, 4 dr. In 2 h. heaviness in head, especially forehead, as if it would fall out ; heaviness in eyes ; when reading, letters run into each other ; at 4 p.m. stiffness in nape ; forced to attempt eructation, without succeeding ; chilliness ; drawing in r. testicle throughout d. 9 p.m., 3 dr. Phantasies unmeaning and incoherent, whilst half asleep, till midnight; fear of death, and of serving in army. 4 a.m., awoke with pains all round sternum, as if it were pressed in, till about 5; from 5 to 6, strong perspiration, which removed pains in chest.-9th. After rising at 7, was so peevish, weary, and exhausted that I was obliged to discontinue the doses. This day's sufferings continued for 3 d., and then quickly disappeared. (Ibid., 158.)

1. a. H-s, a schoolmaster, slender, thin, with a sickly look, very sensitive and excitable, but soon comes to himself ; has had several illnesses since youth, but is now quite well.-Nov. 24th, 1861, 9.45 a.m., I took the medicine sent for proving by Dr. X-, 100 dr. at once.* In h., nausea set in twice, but very slight ; then pain in r. side of forehead, and at noon pain on a small spot behind l. ear, as if from slight blow, only for a short time. At 1.45, pain on 1. shoulder, as if I had lain too long on it ; sleepy in e.-25th. In e., sleepiness. 10 p.m., pain in r. forehead, as if from blow, only for short time ; drawing and stiffness in nape.-27th. Pain in shoulder shows itself also in arms, especially 1.; all afternoon, comfortable warmth all over.-28th, p.m. Warmth increased ; pulse feeble.-29th. Pain in shoulders, nape, and arms, down to wrists. These pains particularly affect 1. side, and either commence p.m. or become more continuous and sharp then , whilst the other sensations soon disappear.-Dec. 3rd and 4th. In e. , drawing pains in parietes of abdomen ; spirits in general good. b. Dec. 9th. From this date I took same medicine again, but only about 6 dr. in a cup of water twice a d., m. and e. After 9 a.m. , pain in penis and testicles ; dull headache in forehead ; head heavy; stiffness and paralytic pain in nape ; then pains in anus and perinæum, which soon ceased. P.m., pains of nape, 1. shoulder and arm increased considerably ; besides I still had drawing pains in back and chest. In e. all pains were gone, except in head.-10th. Nape stiff and painful ; pain increased in 1. shoulder and arm ; pressive pain in chest and back, which spreads to between shoulders. In e., pains in parietes of abdomen on 1., increased by contracting abdomen ; also pains again in genitals, of short duration.-13th. About noon, strangury ; p.m., drawing in both hips ; on 1. side of spine, where ribs cease, pain, as if from blow, for a short time, in a small spot ; then same pain in r. side of spine ; moreover, on r. ischium, pain as from blow, and lastly, a similar pain in l. cheek-bone. Pressive pain in liver, about an inch from scrobiculus cordis ; pain in middle of r. thigh as from blow. In e., insulated stitches, like pin-pricking, in different parts of skin ; pressive headache.- 14th. Stomach-ache and sense ofdistension, with slight pain in lower bowels ; pain as before in l. arm; feeling of cold in stomach and some distension, as if spasm of stomach were commencing ; at same moment, wandering pains in alldirections in back, to up between shoulders. In e., stitches in skin in individual parts ; when in bed, pain in little toe of l. foot and the one next to it, as if from blow ; same pain in l. thigh, three fingers' breadth from hollow of knee. In m., pain in forehead, especially at root of nose.- 16th. Pains in chest and back, strangury, and some abdominal pain ; pain in arm and nape, as before ; likewise head pains.- 17th. Pain as from blow in second phalanx of 1. ring finger; pains in region of liver and spleen, in neck, back, and chest; pain in 1. metatarsus beneath, as from blow ; dull pain in forehead.-19th. In forenoon feeling as ofsand in eyes, with tears ; headache continues. As the pains in the arms, neck, back, chest, and region of stomach were too unpleasant and lasting, I ceased * Nature of preparation not mentioned.-EDs .

taking the doses, after which the pains gradually disappeared, and were quite gone by the 29th. c. Jan. 2nd, 1862. This m. at 10.30 I recommenced medicine, taking only 3 dr. In e. pain in forehead.-3rd. On account of the trifling effects ofyesterday's dose, I took 6 dr. at 10 this m. P.m. , pains in head increased very much (like those arising from intoxication ) ; at 2.30 former pain in neck and shoulders recommenced.-4th. Nose stuffed on awaking ; spot behind upper part of sternum pained me on coughing as if raw ; much coughing, especially in m.; cough fatiguing as in consumption, with much expectoration deep from lungs ; itcould not be repressed on moving after awaking, whilst rattling in chest increased. Expectoration in large lumps, got up with difficulty. From Ist to 3rd d. fits of coughing were accompanied with pains behind sternum, especially at n.; much mucus in nose, obliging me to change my handkerchief daily. I had no recollection of having caught cold. On Dec. 10th I was similarly affected with catarrh, without being aware of having caught cold. (I did not mention this catarrh before, as I ascribed it to having unconsciously caught cold ; but as all its symptoms have been so exactly repeated, I cannot but regard it as the effect of the medicine. On account of the catarrh I discontinued the doses.) d. After symptoms had abated, I recommenced on Jan. 12th, and took 6 dr. every m. at 7. Towards e. former pain in arms reappeared, but very slightly ; pain in head from forehead to nasal bone.-13th . Continued pain in head. About II a.m., strangury. P.m., the pain in head became more violent, extending to occiput ; pain in scrobiculus cordis, and in back opposite. In e. bronchial catarrh. In pit of throat, and behind upper part of sternum, sensation as of dust, not removed by coughing.- 14th. Headache continues uninterruptedly, more or less ; catarrhal feeling ; neck a little stiff. In e. the paralysing pain, hitherto in arms, attacked middle of r., then 1. thigh, afterwards 1. leg, and lastly, 1. foot ; itching in glans penis, which did not last long.- 15th . Stiff neck ; former pain in l. shoulder, but not so severe ; head heavy, and pain in forehead, which only abated occasionally. In middle of upper part of r. thigh, pain as from strain ; cold in head, with some heat.- 16th . But little pain in 1. arm ; neck stiff ; pain in head ; pain in r. knee, which soon disappeared ; a little aching in abdomen, with feeling of distension ; running at nose, and some cough ; pain in r. thigh, as from much walking.-17th. Headache ; pain in back, especially on rising from sitting position, or from stooping.- 18th . Headache in forehead ; pain in back as before. 19th.-From afternoon till bedtime dull pain in l. forehead ; some pain also in abdomen towards e.; pains in sacrum continue.-20th. From 8 to 10 dr. 3 times. The pain in r. shoulder, as well as in arms, was slight, and of short duration ; the pain in sacrum as before ; burning pain in r. upper and lower jawbone, which extended to cheek, and exactly to r. half of both lips, accompanied with single shooting pains drawing here and there, and often ceasing, worst in e. after going to bed. In the upper jaw I have only one useless double tooth, which likewise participated in the suffering in e.-21st. Same doses. Pain in sacrum as before ; rumbling in

abdomen, with some distension; emission of urine by drops with more urging to urinate; the old pain in r. shoulder ; toothache after going to bed as before, exactly whole r. side offace affected ; a fit of general coldness which lasted for 2 h.; cold feet.-22nd. 12 dr. 3 times ; urgent call to stool. After awaking, and on rising, cough and sensation of dust under sternum ; pain in r. thigh as well as in 1. arm ; expectoration easily detached ; 1. ankle pains. In afternoon pain in r. upper jaw, as severe as before in e.; distension of abdomen ; itching in skin of r. leg, so severe that some spots were scratched raw; shooting pains in anus, lasting about half a d.-23rd. 8 dr. thrice ; a little hoarse in m.; cough ; raw feeling behind sternum ; immediately after rising, urgent inclination to stool ; pain as from over-exertion in thighs ; some shortness of breath and oppression of chest. In afternoon pain in r. upper jaw, which after going to bed became so agonising that I was obliged to suspend the doses.-24th. Took nothing ; itching of skin of legs ; feeling of indisposition ; chill. In e. pain in r. jaw as before.--25th . Pain in 1. arm ; catarrh pretty strong, often with nose stuffed ; voice hoarse ; pain in teeth, involving indeed whole side of face, but not so severe ; raw sensation behind sternum. In e. shivering fit which lasted h .-26th. Took nothing; head stuffed in m., worse in a warm atmosphere; pain throughout d. in r. upper and lower jaws and cheek-bones, but more supportable than before; head confused in e.; hoarseness ; pain in r. thigh as before, disappearing at rest.-27th . Took nothing. Coryza is still present, as well as catarrh of chest ; toothache affecting whole r. face, bones, lips , and cheeks, aggravated by warmth, but alleviated for the moment by cold, and cold water. Ine. a dragging feel at anus.-28th. No pains remaining. e. June 19th, 8 a.m., 6 dr. of tinct. in water. I had observed myself for several d. previously without being able to discover any symptoms. Half an h. after taking dose frequent urine, continuing throughout the d. At 12.30, paralytic pain in r. shoulder, which continued h. In e. occasional prickings of skin as if with needles.-20th, 8 a.m. , same dose. At mid-day, pricking as yesterday. For about a m. pressive pain in squamous portion of 1. temporal bone. At 3 p.m., repeated dose. At 6, much pricking here and there in skin ; heaviness in head ; stiff neck ; creaking in cervical vertebræ on moving neck ; general feeling of cold, especially in hands and feet.-21st., 8 a.m., same. At 1, feeling ofcold, especially in hands and feet. At 4, fit of dry coughing. At 7, dryness in throat, with feeling as of dust in it; pricking sensation here and there in skin, with incessant feeling of cold, especially in hands and feet. At 9 p.m., drawing in anus ; awoke at n. with spasmodic pressure within sternum, seated about middle of same, on spot of about 2 in. diameter. The pressure spread towards bronchial tubes, with feeling of constriction in latter ; fear of dying, with desire to eructate, which, however, was ineffectual.-24th . Úp to this date, daily continued stiffness in nape, with cracking ofcervical vertebræ on moving neck. At 9 a.m., feeling of coryza, and after 10 fluent coryza with much sneezing. At 3 p.m., took same dose ; at 5.45, painful drawing in 1. shoulder.- 25th. Pressure on crest of ilium, more on r. than l. 4 p.m., eructation once with pyrosis which

soon ceased.- 26th. On awaking, general perspiration. 8 a.m., took same dose ; at 8.45, drawing in anus ; at 9, sense of distension and of cold in pit of stomach, with diminished appetite; pricking here and there as if with needles ; stiffness in nape with cracking of cervical vertebræ on moving neck ; head confused ; tongue coated white ; at 4, violent fit of chilliness ; eructation, pyrosis and nausea with feeling of being downright ill ; pain in lumbar vertebræ ; abdomen distended with wind. On account of incessant chill, I went to bed at 7, but could not get get my feet warm till about 10, though I applied a hot brick. Four times in n. copious watery whitish stool with nausea.- 27th . Towards m. two watery stools. Towards e., moist skin.-28th . No stool .- 29th. Evacuation normal. f. July 11th. As I had no other sufferings up to this date, I took 6 dr. at 8 a.m. At noon pressure on r. crest of ilium; stiffness in nape ; crackling of cervical vertebræ on moving neck; distension of gastric region. In afternoon feeling ofcold in feet. In e. diminished appetite ; digging in intestines, with some degree of nausea. A little lump on edge of upper lip on 1. side, afterwards forming a white blister, opening of which was followed by continued burning pain.- 13th. Took 6 dr. at 8 a.m.; at 11, pain in lumbar vertebræ. Towards e., fit of coughing ; sensation like dust in trachea and behind sternum, which cannot be removed by coughing.- 14th, a.m., cough as last e. II a.m, took 6 dr.; p.m., drawing in anus. In e. an uncomfortable feel in abdomen, with nausea.- 15th. Pressure on crest of ilium ; unusually soft stool ; cracking in cervical vertebræ on moving neck, with pain in muscles of nape; tongue coated white ; diminished appetite ; cough with sensation of dust in trachea ; peevish temper; dislike to speaking. Next d. no more suffering. g. 22nd, 3 a.m., took 12 dr. in water ; nausea in h.; towards e. fit of chilliness with chattering of teeth, and cold hands and feet ; peevishness ; confusion of head; cold feel in gastric region.-23rd, 9 a.m., took 6 dr.; shortly after, paralytic drawing in l. arm ; pricking in skin ; cold feeling, especially in hands and feet.-24th . Aching sensation deep in hypogastrium ; paralytic drawing in nape ; sensation of distension in r. hypochondrium.-26th, 3 p.m., took 8 dr.; directly after stiffness and paralytic drawing in nape, with sensation on moving neck as if it were broken. 27th. On awaking pain in forehead ; 8 a.m., took 10 dr. Inh. movement in abdomen,with nausea ; pressure on crest of 1. ilium.-29th, 8 a.m., 6 dr., and 3 p.m., 6 more. At4 p.m., nausea, peevishness, pressure on small spot in liver at bend of ribs in linea mammalis ; paralytic drawing in r. shoulder ; weight in head ; stiffness in nape.-30th. Aching in intestines ; drawing in anus ; pain like pinching on small spot on r. side ofglans ; peevishness ; confusion of head ; nape as if broken on raising head ; pain in l. cheek-bone ; skin painful to touch close above 1. brow.- 31st, a.m., pain in l. cheekbone ; pain in hypogastrium. (Ibid., 165.) 18. District Recruiting-Sergeant S-:-I am 35 years old, of excitable disposition, sound in body, with exception of slight rheumatic pains, which I formerly experienced in various parts of my body, but of which I have had no return for a long time.

a. On Nov. 19th, 1861, at 1.30 p.m., I took a teaspoonful of tinct. Half an h. afterwards, feeling as if hair 2 inches above forehead, and at back of head, were bristling up on end. An h. later, two stools in quick succession, my usual habit being an evacuation in m. only. Between 3 and 4 p.m., dry heat set in over whole body, which ended in strong fever ; pulse strong and full, with oppression and pressure in stomach . The oppressive feeling moved upwards towards chest as high as clavicles. At 4.15, burning pain in cheek-bones, moving thence to eyelids, with pain in forehead over eye ; thence pain proceeded to occiput, and disappeared towards 5 ; drowsiness after dark ; lying in bed, but unable to sleep, from 10 till 12, then a good sleep till towards m. -20th. From 3 till half-past, dry heat as yesterday, pulse stronger, beating from 110 to 120. At half-past 3, fever began more violently, and ended very suddenly after 4. Burning sensation in eyes lasted till half-past 4; some thirst; drowsiness in e.; comfortable sleep from half past II till m.- 21st. Fever at same time as on 19th and 20th, but attack was slight. In e., pressure in temples ; slept well ; cheerful state of mind. I remarked an unusual feeling of good health. Perspiration was insignificant ; dreams confused, but not painful. b. December 8th. At 7 a.m. and at 7 p.m. took 2 dr. No change throughout d. At 6, in e., suffered from heartburn ; 5 m. after taking the 2 dr. it disappeared. From 10 till 11 , restlessness in bed ; dryness in throat ; nausea and flow of water in mouth ; good sleep from 11.30 till nearly 7.30.-9th. Two dr., as on 8th. No effect.- 10th . Four dr. as on 8th. Excited, but in other respects pleasant state of mind. In bed, rheumatic pains in occiput, also in forehead.- 11th. Four dr. at 7 a.m. and at 12 p.m. No symptoms in forenoon. From 3 p.m. drawing together of abdominal muscles, and pain round navel ; digging in stomach. 12th and 13th.-Took nothing. 14th and 15th.-Six dr. at 7 a.m. and 2 p.m. No a.m. symptoms on 14th. At 12, crawling and itching in rectum ; 5 m. after, pricking in great toe. The same at 10.30 p.m., followed by renewed crawling and itching in rectum and scrotum, which lasted for 3 or 4 m., with frequent inclination to urine. At 7.30 p.m., another stool.- 15th . At 3, crawling in perinæum and glans penis, extending to toes and point of nose, later in perinæum; stitches in lower part of 1. lung. At 4, burning in eyelids ; watery eyes. After 5 I observed nothing more.- 16th, 17th, and 18th. Took nothing in consequence of rheumatic pains here and there, restlessness in bed at n., and general indisposition.-19th. Eight dr. at 7 a.m. and 2 p.m. At9, pains in navel ; at 10, crawling in r. hand, and at half-past 10, in perinæum. At 2, a little nausea rising from stomach. At 2.45, stitches in thorax, tense feeling in r. region of occiput. At 5, crawling at anus ; 5 m. later, in forehead ; rheumatic pains over whole body.-20th and 21st. Took nothing.-22nd. Eight dr. at 8 a.m. At 12, crawling in r. thumb, and at 8 in point of nose. From 23rd to Jan. 1st took nothing, as itching and crawling sensations became insufferable. During this time I observed no other symptoms.-2nd. At 1.15, took 9 dr. At 2, burning pain in eyes. At half-past 2, crawling in front joints of toes of r. foot. At 2.45, rheumatic pain in r. forearm. At 3, drawing in r.

testicle ; 5 m . after in upper incisors ; 5 m. later, drawing in r. testicle. At 4, drawing pain in r. side of occiput ; 10 m. afterwards, drawing in r. testicle ; excitement; good sleep after 11.-3rd. Eight dr. 8 a.m. From 9 till half-past 9, rheumatic pains in r. wrist ; at 10, in the point of nose ; 5 m. after in sinciput ; at 10.45, in r. forearm. At half-past 1 , took 8 dr. At 2, pressure in eyelids, with tears. At half-past 4, pain in pit of stomach. At 4.45, crawling in point of nose. At 5, tense feeling in cheeks between eyes and mouth. At half-past 6, nausea. Athalf-past 10, painful crawling in rectum . The rheumatic pains move about through whole body ; good sleep from 11.-4th. Took nothing, believing that the rheumatic drawing might be the old complaint, but this opinion was not confirmed. At 3.45, spasmodic pain in pit of stomach. At half-past 8, pricking in r. great toe. At 9, spasmodic pain in cardiac region on r. side. From half- past 10 till 12, restlessness in bed, afterwards slept ; frightful dreams twice.-5th. At half-past 10, took 8 dr. in water. At 11.15, same pain as yesterday in cardiac region ; when this ceased, spasmodic pain in r. eye which lasted for 2 m. In e. excitement of body from 10 till half-past 11.-6th. At an early h. fluent coryza, without any cause for it. At half past 8, took 8 dr. At 9, stitch in third joint ofr. forefinger. At half-past 9, stitch in second joint of same finger. At half-past 5, stitches in fore part of lower region of thorax, which move thence into intestines below navel. At 7, stitches close under heart ; no sleep from 10 till half-past 11 , then sound sleep till half-past 7 ; great lassitude in early m.-7th. At 10, took 8 dr. At II , oppressive pain in cardiac region above.- 8th. Took nothing. At half-past 10, stitches under ribs on r. side. At 12, rheumatic pains extending from 1. shoulder to elbow. In consequence of the doses taken the previous days, I am in such an excitable state of mind that I feel myself obliged to stop for some days. The symptoms are so varied that some cannot be recorded. My complexion is a greyish yellow, so that my unhealthy appearance strikes everyone ; my hands also are become yellow ; my bowels are confined since two days , notwithstanding efforts to move them ; I slept well,-on 8th, from 11 ; on 9th, from half-past 10 ; on 10th, from 12 ; on 11th, from 1.15 ; on 12th, from II at n. till 8 in m. In intermediate hours from 10 much restlessness in bed. On 12th I was troubled with distressing dreams. On 13th my complexion, as also my hands, had resumed their natural colour. From 8th to 12th my stools were of a reddish-white colour, instead of a brown grey as formerly ; they were also harder than usual. c.- 12th. Took 8 dr. at 8 a.m. At 10, stitches between shoulders . At 12, crawling in perinæum. At 4, burning in urethra on making water. At half-past 5, oppression between shoulders.- 15th. At half-past 8 took 8 dr. Throughout day dull pain and heaviness in head. At 8.45 p.m., constrictive pain between shoulders. At 10, crawling in rectum, immediately after which considerable oppression of chest. Slept well from half-past 10 till halfpast 7 in m.-16th. Took 8 dr. at half-past 8 in m. At 12, crawling in rectum, and same at 3 p.m. At half-past 1, took 8 dr. At 3.15, oppression of the chest, and rheumatic headache. From 2 till nearly 6, heat in eyes, relieved by closing them. Slept from half-past 11.- 17th. Took 8 dr. at half

past 8. At 10, stitches in perinæum. At 10.15, stitches in r. side under scapula, and 5 m. afterwards same in perinæum and testicles ; 5 m. after in r. shoulder. At half-past 11 , same in scrotum. My whole body is in an excited state. The symptoms appear so frequently that they can no longer be recorded. Stool at half-past 12, light red and painful.-18th. Took nothing. At 10 p.m., stitches in liver. Unusual excitement throughout d., as well as at n. Slept from half-past 11, restless and dreaming, but not distressing dreams.-19th. Cheerful. At 3, pricking in liver; from 10.30, sleep, with light dreams. -20th. At 8.30, took 8 dr.; no change a.m.; 3 p.m., congestion in occiput ; from 4.15 to 5, cheeks burning ; after 10, sound sleep.- 2Ist. At 1.30 took 8 dr. From 4 to 6, congestion in head ; eyes and cheeks especially hot ; 5 p.m., crawling sensation in rectum.- 22nd. Took 8 dr. at 8 and at 1.30 ; burning in eyes all d.; lips dry, brittle, and crusty; itching sensation in meatus auditorius, first of one ear, then the other ; from 10, sound sleep.-23rd. Took 15 dr. at 8 ; nothing remarkable a.m.; lips better. At 2.45, spasmodic pressure on stomach ; at 2.30, considerable congestion with heat of head, till about 4; at 2.45, pressure on stomach, with nausea.-24th. Took 8 dr. at 8 and at 1.30. At to and II , crawling in perinæum and rectum ; burning in r. eye; at 4, crawling in perinæum; dryness of nose and lips.-27th. Took 8 dr. at 8. At 10, pricking in r. shoulder and testicles ; at 11 , pricking pain in forehead, r. side ; at 2 p.m. , almost uninterrupted itching of perinæum ; lips dry, eyes burning ; at 4, pricking in r. great toe, repeatedly ; at 4.30, pricking in glans and r. great toe.-28th. Took 8 dr. at 8 a.m.; head confused.-29th. Took 8 dr. at 8. At 5 p.m., spasmodic contraction ofregion of navel ; then pricking pains in r. meatus auditorius and upper part of forehead. -Feb. 15th . During whole fortnight since Jan. 30th troublesome tormenting itching in the anus and rectum.-March 8th. Since Feb. 15th slighter itching of the anus and rectum, from d. to d. From March 8th I suffered from noise in the ears and hardness of hearing for some weeks, so that I had to discontinue the proving for some time ; as the noise in ears did not go off of itself, a dose of sulphur caused profuse perspiration, and the noise ceased. d. Having felt no inconvenience for more than a week I ventured on April 6th to resume the proving.-April 6th. At 11 , 1 , and 3, took 3 dr. each time in water ; in 2 h. after, dull pain in temples. -7th. At 11 , 1, 3, and 6, took 3 dr. in water ; in afternoon, drawing pains all over body, with fluent coryza ; violent drawing pains from crown to r. temple, so that I had to go to bed at 8.-8th. Took no more on account of continued pains as yesterday.-9th . At 9, 11 , 1, 3, and 6, took 2 dr. in water ; at II , pricking in point of nose.- 12th. At 8, 11, 1, and 5, took 2 dr.-13th . Drawing pain through lower middle incisors early ; at 8, in r. cheek-bone.- 14th. At 7, 9, 11 , 1 , and 8, took 2 dr.-15th. At 8, 10, 12, 2, and 10, 2 dr.; urine soon after passing it became reddish and turbid ; stool whitish red.- 18th. At 9, 12, and 10, 3 dr.; at 3 p.m., itching in rectum, and at 4 in point of nose ; general heat, with restlessness, and paralytic sensation in the legs all d.; urine reddish ; pressive pain in occiput. 7

e. Up to the beginning of June I had to give up the proving for want of time for observing. As far as I could notice I had no suffering during the interval.-June 11th. At 8, 10, 2, and 10, took 2 dr. ; at 8 p.m., cutting in intestines, all round navel.-12th. Sleepless till after II ; in m., tongue shaggy, coated with grey, which could be partly scraped off; hawking up of lumps of phlegm ; at 8, 10, 12, 2, 6, and 8, took 2 dr.; ringing in ears, yawning, burning and redness of cheeks.- 13th . Sleepless till after II ; distressing dream that I was going to be shot. At 8, 10, 12, 5, and 10 o'clock, took 2 dr.; from 5 to 6, burning of tip of ear, pressure in upper jaws ; about 8 p.m., chill ; at 10, dull pressure in r. cheek-bone, extending to r. ear ; tongue coated grey all d.-14th. At 9, 11 , 1 , 3, 6 and 10 o'clock, took 2 dr.; at 3 p.m. , pressure with ringing in r. meatus auditorius ; at 5, itching in anus, pricking pain in forehead several times ; tongue cleaner.- 15th . At 9, 11, 3, and 8 o'clock, took 2 dr. At 11 a.m., toothache in 1. upper jaw.- 16th. At 9, 11 , 12, 3, and 5, took 2 dr.; sleepy p.m.; at 3, pain in r. cheek-bone and upper part of occiput ; at 7, pressure and constriction from r. shoulder-blade, spreading through chest towards sternum ; pressure on larynx, as if it was constricted ; oppression of chest.- 17th . Same symptoms, so I took no more ; at 5 p.m., burning in tips of ears.- 18th. Same pressive pain in chest, with great tightness .- 19th . At 10, 12, and 2, took 3 dr.; heat all over head all d.; tearing from cheek-bone towards ear, and all around it, on r. side ; from thence it extends towards occiput in upper part, towards suture with parietal bones ; feeling as if hair was bristling.- 20th. Heat, with feeling as if hair bristled ; feet and tips of fingers cold. -21st. At 7.30 and at 2 p.m., took 5 dr.; at 8.15, constrictive pressure in scrobiculus cordis, dryness in throat, shortness of breath, and ringing in ears ; feet and fingers cold.- 22nd. At 10, took 5 dr.; feet and tips of fingers cold ; pressure on bladder, with frequent scanty urine ; hair falling off.-23rd. Took none ; at 11 , itching in anus ; at 5, pain in r. little finger.-25th. At 9 a.m., 5 dr.; at 3 p.m., burning in eyes, then in forehead ; at 5.15, itching on r. ankle, at 7, on 1.; at 9, pricking in r. wrist, itching in r. ear, burning in tips of ears, and reddened cheeks ; loose stool.-26th. Took none, stool as yesterday.-27th and 28th. Constipation.-29th . At 9, 5 dr.; at 10, three pappy light grey stools.- 30th. Perspiration on awaking, after distressing dreams ; dryness in nose and throat. At 10, took 10 dr.; at 11 , itching in r. ear, at 11.15, in rectum ; at 5.30, sense of swelling in r. cheek-bone, pressure in eyes, burning in tips of ears, and cold in tip of nose ; at 6, itching in anus, burning cheeks, glitter before eyes, itching in ears and anus, excitement and restlessness, frequent yawning, pricking close under 1. shoulder-blade. -July 1st, m., sweat after good sleep and disagreeable dreams. At I p.m., 10 dr.; from 3 to 7 p.m., heat in face ; at 9, rigor ; sleeplessness from 10 to 11.-2nd. At 6 a.m., 10 dr. At 11.30, shooting on inside of 1. lower eyelid ; burning in lower eyelids ; at 2.45 p.m., pain in nasal bone ; stuffed cold ; at 5 p.m., dazzling before eyes.-3rd. At 11 a.m. , 10 dr. Immediately afterwards pain in r. shoulder ; ringing in ears ; at I p.m., aching in chest under both arms, constriction as though chest were

tightly bound ; itching in perinæum ; at 5p.m., burning in tips of ears ; dull aching in r. temple extending towards vertex ; from 7 to 8 p.m., rigor with chattering of teeth.-4th. At 8 a.m., 10 dr. Constant chilliness . -8th. At 2p.m., 10 dr. At 5 p.m., tensive pressure below 1. scapula ; aching in temples ; ringing in ears ; burning in l. ear, whilst r. is quite cold. At 6 p.m., aching in sacrum, which slowly rises to below scapulæ, and lasts till 10 p.m.; itching in point of nose.- 9th. At 10 a.m., 10 dr. At 8 p.m., itching under 1. great toe ball, and shooting under l. little toe ; falling out of hair continues. At 9 p.m., aching under r. scapula ; burning in forehead. About 10 p.m., pain in occiput, in the midst of which I fell asleep.- roth. At 1 p.m. , 10 dr. At 5, shooting on border of 1. ribs ; at 5.15, aching pain in r. thumb ; at 5.30, shooting in frontal bone right over 1. eye ; thereafter on 1. side of occiput. At 6 p.m., 10 dr. At 7, shooting in r. heel ; ringing in r. ear ; dryness in throat ; great weariness.- 11th. Dream of a journey at n. At 6 a.m., 6 dr. Roughness and dryness of throat ; swollen belly ; at 8.45, burning in r. thumb-ball ; about 10 a.m., sleepiness, dazzling before eyes, shuddering. At I p.m. , 10 dr. At 1.30, violent throbbing in temporal arteries, with headache ; aching pain in r. temple, then in r. parietal bone, lastly close over r. eye ; itching in l. ear ; viscid ear-wax of a whitish colour, like flour paste ; at 6 p.m., burning in l. ear, whilst r. is cold.-14th. At II a.m., 10 dr. From 3 to 4 p.m., burning in cheeks ; shooting in inside of r. eyelid ; aching in r. temple and itching in r. ear.-15th . At 10 a.m. , 10 dr. At 4 p.m., general dry heat, with pulse 100 to 110 ; cold ears ; pain behind r. ear, in forehead and vertex.-16th. At 9 a.m., 5 dr. At 11 , dryness and itching in 1. nostril ; from 1 to 2 p.m., tearing in meatus auditorius and temporal bone ; at 8, aching pain in r. malar bone ; at 10, itching in 1. toes, at 10.15 over r. ankle.- 17th. At 8 a.m., 5 dr. At 10, itching in r. sole.-22nd. At 10 a.m., 5 dr. Itching on coccyx ; at 1.30 p.m., stitches on inside of 1. lower eyelid ; dryness in throat and nose ; at 1.45, drawing in l. great toe ; at 2, pain in r. malar bone and below 1. scapula ; at 4, short jerk in upper incisors ; pain in l. ankle, especially when walking.-23rd. At6.30 and 11 a.m., and 4 p.m., 5 dr. At I p.m., itching in anus ; at 4.30, cold ears ; dry nose ; hot forehead, with headache ; constriction of stomach. At 4.45, itching in second joint of 1. middle finger, at 7.30, of point of nose, at 7.45 in anus ; at 8, heat in nose ; from 10 to 11, heat and burning in ears, point of nose, malar bones and forehead ; itching in r. sole.- 24th . At 8 a.m., 5 dr. From 10 to 11 , pain in sacrum ; shooting pain in 1. parietal bone. At 11, 5 dr. At 12.30, pain under r. scapula. At 1.15 p.m., pain in 1. side of chest ; shooting pain in r. parietal bone ; itching in 1. nostril ; pinching pressure below 1. clavicle and up neck ; flying heat of face. At 3, 5 dr. Restlessness in bed till after 11.-25th. At 9 and 11 a.m., 5 dr. At 12, itching in 1. nostril ; at 12.15, shooting in 1. index ; wandering pains throughout body ; ringing in both ears ; at 12.30, dull aching pain below r. scapula ; aching in stomach ; at 3, pain in r. upper eye-tooth ; till about 6 p.m. , pinching in back, extending round 1. ribs ; at 6, shoots in l. index. (Ibid. , 188.)

1. a. District Secretary P-. On Nov. 19th, 1861 , p.m., Dr. Xgave me a small teaspoonful of a bitter medicine with which I was unacquainted, and he wished me to tell what I felt after taking it. In a short time I had eructations without any particular taste, and a discharge of flatus. Later, sudden shooting in r. upper eyelid, which soon went off. Then there came on a rush of blood to head and chest, which lasted some h. I felt heat in face and burning in ears ; a certain but not great degree of anxiety of chest, during which arms and legs were rather cold, particularly so towards e. The next d. the fever recurred about the same time, but did not last so long. Later, no particular symptoms except a better appetite. b. I am 34 years old, of middle size, rather delicate constitution, and, as my habits are sedentary, I have suffered much for many years from colds, which, however, of late years have not been so troublesome, owing to diligent washing with cold water, and in summer cold bathing. I am also troubled with a weak digestion, at least I suppose so, as I have often heartburn, especially at n., but also by d.; I have also piles, which rarely bleed. Hitherto I have seldom suffered from cough, but have often a considerable amount of expectoration (without cough) My temperament has not much of the phlegmatic in it, but is rather restless and passionate. My manner of living is regular ; it may happen that I sometimes eat more than I ought ; I am moderate in drinking ; I seldom touch spirits, and then only in small quantities, never in the house ; I take Bavarian beer several times in the week, on an average two pints. For some time during last summer and autumn I had slight epistaxis after taking beer. At present I am quite free from symptoms. From Dec. 10th I have taken the medicine given me by Dr. X-, by drops, in a cupful of water.-Ioth. In e., 6 dr. Thereafter eructation and transient formication in forehead.- 11th. In m. 6 dr. Soon afterwards dull headache ; drawing in shoulders ; transient cutting belly-ache and drawing in 1. meatus auditorius ; fluent coryza. From thenceforward to 20th inclusive took every m. and on some e. from 6 to 8 dr.-12th. Cramp-like belly-ache betwixt navel and scrobiculus, not lasting long, soon after taking medicine.- 13th. Pain in bowels as on 12th, but not so severe. In e. 6 dr., followed by stitches in chest.- 14th . Ringing in l. ear ; no other symptom observed.- 15th. No effects.-16th. Some belly-ache and transient sacral pain ; eructation ; soon after taking, bowels opened, not diarrhœic ; I have had this regularly each time after taking medicine.- 17th. Headache and fluent coryza. After taking the medicine again in e. deep-seated pain over pubes.- 18th. Rumbling in bowels and some diarrhea ; disagreeable cutting feeling in urethra during and after urinating.- 19th. Rumbling in bowels and some belly-ache ; at n. and the following d. pains in 1. side.-20th. In m. rumbling in bowels and diarrhea ; in e. at first no effects, afterwards tearing in l. side of occiput, over ear and towards front ; eructation ; coryza. I now made a pause until Jan. 6th, on account of violent catarrhal fever. c. Jan. 6th- 16th. Took every m. 6-8 dr. On 6th, no effects. -7th. Violent painful tearing in r. arm and head ; paralysed feeling in r. arm.-8th. In m. no effects ; in e. itching in rectum, then tear

ing in r. arm and paralysed feeling in it ; itching and shooting in different parts ofskin. Till 16th, no particular effect, except itching of skin of back, calves, and shins. On m. of this d. some distension of stomach and abdomen, and much itching in skin all over body.- 17th. In m. 12 dr. Itching of skin ; shooting on different parts of skin, especially on back, arms, and legs ; stomach-ache, alternating with violent headache from nape to forehead and temples, which returns. In afternoon ill-humoured, cross ; repeated attacks of violent throbbing pains from nape to occiput and forehead. I have dreamt much since taking medicine, but not slept badly.-20th. In m. 8 dr. Violent itching on calves and shins, also on back and forearms, sides of the hips to axillæ, also on ribs, particularly in the afternoon and towards e., so that I scratched my calves till they bled.- 21st and 22nd. I went on a journey, and took no medicine. Itching on the forehead and temples continued.-23rd. In m. 8 dr. Itching of skin.-24th. In m. 8 dr.; in e. 6 dr. The same.-24th. In m. 8 dr. Itching of the skin continues ; single pimples on back and loins.-25th. Immediately after taking dose, itching on belly.-26th and 29th. I was away and took no medicine.-27th, 28th, 30th. In m. 8 dr. Itching of skin.- 31st. In m. 14 dr.; in e. 16 dr. Itching here and there on skin continues, and I scratched my arms till they bled. In e. transient aching pain in 1. scapula ; call to stool ; eructation previously. On the whole I feel much better after taking medicine ; I have a better and heartier appetite than before ; feel stronger and more vigorous, and complain less of cold feet, from which I used to suffer so much in winter. d. On April 5th I recommenced proving. In the interval I felt quite well. At 7 a.m., 10 dr. in a cup of water. Soon afterwards pressure in abdomen and urging to stool, without diarrhea ; pressure in abdomen (umbilical region) lasted an h.; thereafter itching in skin of abdomen, breast, and ribs on 1. side.-6th . At 7 a.m., 12 dr. Itching of skin ; single small shooting pustules in different parts of skin.- 7th. At 7 a.m., 15 dr. Soon afterwards dull pains in forehead ; ill humour ; stool brown and watery ; continued pains in teeth, which obliged me to leave off the proving. e. 21st. At 7 a.m., 12 dr. Weariness all d.- 22nd. At 7 a.m., 10 dr. Soon afterwards eructation ; pain in bowels and gastric region ; discharge of flatus ; call to stool without diarrhea ; weariness all d. -23rd. At 7 a.m., 9 dr. Itching of skin, and small pustules on various parts ; weariness.-24th. At 7 a.m., 12 dr. Increased itching all over body.-25th. At 7 a.m., 9 dr. Sleepiness ; aching pain in forehead and itching of skin all d.- 26th. At 7 a.m., 9 dr. Until noon fluent coryza ; in afternoon, tearing pains in forehead ; heartburn, which went off immediately after taking 3 dr.-27th. At 7 a.m., 20 dr. Until noon, perspiration on upper part of body, and ill humour ; about 9 a.m., transient pain in l. side of chest. At noon, 12 dr.; at 7 p.m., 20 dr. Thereafter dull headache until bedtime ; sweat at n., also towards m.- 28th. At 7 a.m., 20 dr. Soon afterwards pain in bowels, in umbilical region ; frontal headache and itching of skin ; at noon digging pain in gastric region, lasting after eating. At 7 p.m., 20 dr. Pain above navel comes on immediately after taking medicine ; tran

sient pain in 1. meatus auditorius ; shooting and itching of skin in various parts ; dull frontal pain ; sweat towards m., three soft stools.- 29th. In m. 22, at noon 10, in e. 12 dr. Each time after taking, eructation ; all forenoon pain as before in umbilical region, and itching in anus ; in e., after taking drops, transient pain in l. side of chest, and frontal headache ; perspiration towards m.- 30th. At 7 a.m., 20 dr. Soon afterwards eructations ; violent pressing spasmodic pain in umbilical region for a second only, but often recurring ; in afternoon pain is more constant, spasmodic ; during d. 3 soft stools mixed with mucus. May Ist. At noon, 15 dr. Half an h. after, itching of skin ; tearing pain in r. shoulder ; thereafter pains in 1. chest ; itching in anus and great weariness ; after 2 h. shooting in forehead under skin, followed by dull frontal headache ; eructation and constant itching of skin till e. At 7 p.m., 20 dr. Soon afterwards tearing in r. arm ; sweat towards m.; stool as yesterday ; good sleep, with dreams about ordinary things.-2nd. At 7a.m. , 24 dr. Throughout forenoon confusion of head ; pressure in forehead and temples, especially 1.; shootings in l. chest. At 3 p.m., aching pains close above navel, drawing up to 1. chest ; tearing in r. arm ; frequent discharge of flatus ; in e. 20 dr., thereupon pains in umbilical region and dull pain in forehead. -3rd. At 7 a.m., 24 dr. Immediately afterwards eructation ; tearing in r. shoulder and dull frontal headache ; on awaking, on blowing the nose, thick black blood appeared among the nasal mucus (I had been rather subject to epistaxis). Repeated bleeding of gums in the forenoon. At noon, 15 dr. In h. eructation, itching of skin, tearing in r. shoulder, and shooting in skin here and there.-4th. At 7 a.m., 20 dr. Soon afterwards transient pains in r. chest.-5th. At 7 a.m., 20 dr. Immediately eructation and pain in side, like yesterday ; aching pains right over navel. At 2 p.m., 20 dr. Soon after again same belly-ache and pains, first in r. and then in l. side ; severe fluent coryza. At 6 p.m. , 25 dr. Soon afterwards tension and swelling in gastric region ; shootings on inside of 1. arm near elbow-joint, frequently recurring, also on inner side of l. thigh ; pain in 1. side of chest ; took nothing more till May 19th, and felt no symptoms.-19th. At 7 a.m. , 18 dr. Soon afterwards pain in r. side of forehead ; later still pain all over forehead ; drawing in 1. meatus auditorius ; itching of skin on different parts of trunk. At noon, 18 dr ; at 6 p.m., 20 dr. No symptom except itching of skin .-20th . At 7 a.m., 10 dr. Soon afterwards rumbling in bowels, and 2 h. after, until noon, continued dull frontal headache ; in afternoon, rigor. At 6 p.m., 20 dr. Many dreams, and sweat towards m.-21st. At 7 a.m. , 20 dr. Rigor, and itching of skin all d.-22nd . At 7 a.m., 20 dr. In an h. painful feeling in glans ; frontal headache ; drawing pain from 1. scapula to 1. upper arm, followed by painful drawing in back of 1. hand. At 6 p.m., 20 dr. Immediately afterwards drawing pain from 1. ear to 1. upper teeth.-23rd. At 7 a.m., 20 dr. Soon afterwards rumbling in bowels, followed by dull frontal headache, and later burning-shooting pain in r. metatarsus and bones of toes ; in afternoon no symptoms . At 6 p.m. , 20 dr., whereupon pain in third toe ofr. foot recommenced.-24th. At 7 a.m., 18 dr. Soon afterwards aching pain in gastric region, and pain in 4th and 5th toes of r. foot ;

after this drawing from 1. meatus auditorius to 1. temple ; dull frontal headache ; 2 h. afterwards severe tearing in r. then in l. temple ; tearing pain in thigh ; no symptoms in afternoon.-25th. At 7 a.m., 18 dr. In h. tearing in 1. upper arm and drawing in 1. hand; transient pain in r. chest ; dull frontal headache ; repeated attacks of pain in r. foot extending towards toes ; drawing in 1. side of nape and 1. meatus auditorius ; drawing rheumatic pains here and there all d.- June 2nd. As the drawing pains lasted all yesterday I took no more of the medicine till to-day. At 7 a.m., 20 dr. Soon afterwards pains in r. side of chest, and frontal headache ; urging to stool. At noon, 20 dr. Soon afterwards rumbling in bowels. At 7 p.m. , 20 dr. Violent pain in 1. side of forehead towards 1. temple, soon passing off. -3rd . At 7 a.m. and 7 p.m., 20 dr. Tearing and shooting all d., here and there; worst in r. leg, spreading from above downwards.-4th. At 7 a.m., 25 dr. Soon afterwards transient violent shooting pain in belly right over navel. At noon, 25 dr. Great weariness after dinner ; in afternoon tearing in r. shoulder. At 7 p.m., 20 dr. At n. perspiration and many dreams.-5th. In m., 25 dr. Soon afterwards violent toothache in 1. side of both jaws, which recurs and lasts several m.; aching pains in both temples ; about noon, heartburn and great weariness. At noon, 25 dr. Repeated tearing in teeth of 1. side in afternoon ; the pain spreads into 1. meatus auditorius ; sweat bursts out when pain comes on. At 7 p.m., 20 dr. Continued toothache all n. long.-8th . Toothache continued, with few intermissions, till yesterday, wherefore I took no medicine. At 7 a.m., 20 dr. Soon afterwards toothache in r. side lasting till e.; violent but transient shoots in r. side of chest. At 7 p.m., 20 dr. Toothache again passes to 1. side.-9th . During n. toothache extended to whole l. cheek, but was occasionally also felt in r. side, in consequence of which I took no medicine to-day.- 18th. Until the day before yesterday still frequent attacks of toothache, now on 1. now on r. side, alternating with flying stitches in l. chest. At 7 p.m., 24 dr. Soon afterwards drawing in l. ear and molar teeth.-19th. At 7 a.m., 24 dr. Soon afterwards confusion of head ; in course of 2 h. two stools of ordinary character.-20th. At 7 a.m., 24 dr. Soon afterwards tearing in r. arm ; drawing in l. teeth and 1. meatus auditorius.-23rd. In m., 20 dr. Soon afterwards pinching in bowels and rumbling ; cough caused by irritation in larynx, soon going off; drawing in 1. meatus auditorius. f. July 4th. From to-day I took the drops without water. At 7 a.m., 5 dr. Immediately afterwards violent aching shooting in r. eye, soon afterwards in 1. eye ; drawing in molar teeth and in l. meatus auditorius, afterwards in 1. knee ; slimy taste in mouth ; eructation ; thereafter drawing in teeth, first on r. side then on l.- roth, m. and e., 20 dr., without effect.-11th. At 7 a.m., 15 dr. Itching in rectum ; tearing in teeth here and there.-22nd. At 7 a.m., 20 dr. Immediately after heat in head ; eructation. At 8, same dose. Immediately afterwards shooting in 1. eyelid. At 2 p.m., same dose. Warmth and restlessness in whole body ; eructation ; sweat in axllæ ; transient toothache, first on r. then on 1. side ; itching in 1. palm ; shooting in a corn on r. foot ; paralysed feeling in l. forearm ; dull aching frontal

headache ; itching in anus ; tearing in 1. teeth. At 7 p.m., same dose. Shooting and tearing in teeth, first on 1. then on r. side.-23rd. Early in m. tearing in teeth on r. side ; dazzling before eyes, and vertigo, lasting more than h. At 7 a.m., 10 dr. Immediate eructation ; occasional drawing in teeth ; dull frontal pain ; drawing in 1. molars and malar bone. Noon, 15 dr.; no effect. 3 p.m., 10 dr.; tearing in l. teeth. 7 p.m., 10 dr.; same tearing in teeth.-24th. At 7 a.m., to dr. Soon afterwards violent drawing pain in l. upper jaw and cheek-bone, with heat in cheek up to eye.- 25th. At 7 a.m., 15 dr. Immediately afterwards shooting in anus and 1. thigh. At 11, 20 dr. Immediately afterwards eructation. At 7 p.m., 20 dr. Drawing pains in teeth ; fluent coryza.-26th . At 7 a.m., 20 dr. Coryza continues ; itching in anus ; aching frontal headache ; transient pain in r. side of chest ; continued drawing in teeth all d.-27th. On account ofcontinual drawing in teeth took no medicine.-28th. At 7 a.m., 20 dr. Soon flying shoots in r. chest ; drawing in both cheek-bones and 1. meatus auditorius. At 9, 30 dr. Soon afterwards tearing in shoulders and l. arm . At 11 , 30 dr. Periodical toothache ; in afternoon frequent tearings from r. ear into r. teeth .- 29th. Toothache like yesterday. At 7 a.m., 200 dr. at once. Toothache extends into cheek-bones ; tearing in l. arm ; violent shooting in a decayed r. molar.- 30th. Pains returning periodically all n. as yesterday, and are still to-day troublesome.-31st. At 7 a.m., 160 dr. at once. Throughout d. violent toothache, especially after eating warm food ; sweat every m. for five weeks past.-Aug. 3rd. Periodical toothache on 1st and 2nd ; last n. little sleep on account of violent toothache on 1. side.-7th. Toothache not gone yet ; frequent tearing in l. ear and 1. upper arm ; flying stitches in side and pains in chest.- 22nd. For last fortnight toothache has never left me for whole d.; appetite became bad, so that I could eat but little ; pains were worst last n.; they extend into 1. temple and forehead, with heat in 1. side of forehead ; pain is periodically tearing also in l. ear ; as the pains were insupportable they gave me Arsen. 30, whereafter the pains became better ; emaciation ; pale sunken countenance; hypochondriacal humour.-Sept. 9th. The toothache, which always extends into 1. temple and forehead, wherealsocontinuous violent tearing is felt, has recurred almost every d.; Ihave no relish for food ; I feel languid and disinclined for all work ; motions are, on the whole, looser, and occur several times daily ; spirits have been very low for some weeks ; I feel very unhappy and have no disposition to talk.-30th. Until the 16th I suffered daily from toothache periodically occurring, which, however, after returning from a three days' excursion into the Hartz hills on the 17th, did not recur ; my countenance has again a fresh appearance, and my spirits are cheerful ;20.myFrederick appetite also has returned. Augustus ( Ibid.,secretary, R-, private lxxi, 4.) æt. 54, very thin, 5 ft. 8 in. high, strong bones, muscles moderate. Skin white ; complexion pale ; hair blond, thin, soft ; eyes blue ; appetite very good, sometimes almost morbid, continuing after a meal. I have given up beer and cigars, as they are very injurious to my throat, causing dryness and a choking sensation. Character : very easily excited to anger, soon repented of; after a fit of vexation, loss of appetite ; easily affected by

the sufferings or sadness of others, or by reading sad stories ; of a yielding sympathetic disposition, cheerful ; love of music (not noisy music) and song and cheerful society ; make up mind rapidly ; courageous. Other peculiarities : rheumatic sufferings before and during wet weather ; damp, cold, and draughts of air cause suffering ; dry wind in the open air agrees ; dry cold or heat are not disagreeable ; easily tired with standing, or with mental or bodily efforts, the latter readily producing perspiration ; being in a newly scrubbed room, and the smell of newly washed linen, very disagreeable, headache and vertigo caused thereby. a. Jan. 20th, 1862. At 10 p.m., 10 dr. of Ist dil.; slept from 11 till 8 without dreaming.-21st. At 11 a.m., 10 dr. of tinct. At 10 p.m., 15 dr. At 8 a.m., tensive feeling on r. side of head from r. temple to middle of forehead ; at noon, yawning, stretching, drowsiness, as after a sleepless night ; disinclination for work ; laziness all day ; ill humour ; dizzy heaviness and tension on upper part of head, especially in vertex, which pains as if raw when touched, unaltered by rest, motion, warmth or cold, only aggravated by thinking ; on combing hair pains in roots of hair as if ulcerated ; gurgling or quivering movement in front of neck above larynx, without pain, lasting some seconds and returning in a few m., all d. long ; bowels, as usual, regular.- 22nd. At 10 a.m., 20 dr. At 5 and 9 p.m., 25 dr. Undisturbed sleep ; dreams of funerals and corpses ; on rising from bed vertigo, with inclination to fall forwards (for a minute) ; all symptoms of yesterday unchanged. At 10 p.m., the tensive heavy feeling in top of head extended into occipital protuberance, and head feels as if surrounded by a band ; in throat and windpipe choking feeling, increased by breathing, as from taking beer in former days, or strong cigars ; an eruption on dorsum of 1. hand, which was there 16 years ago, and only showed itself every year by a slight desquamation ofcuticle, comes back in increased intensity ; back of the hand is somewhat swelled ; red reticulated patches appear which gnaw and itch without exuding, and then scale off ; constipation.-23rd. At 10 a.m. and 7 p.m. , 30 dr. At 5 p.m., 25 dr. Slept from II till 4 undisturbed ; wide awake from 4 till 5, then sound sleep without dreams till 9 a.m.; no vertigo on rising, but symptoms of yesterday continue unchanged ; fixed pain as if raw in l. lung, which was inflamed 4 months ago, pain increased by deep breathing ; motion hard, knotty, and passing with difficulty, with sore pain in anus.- 24th. At 11 a.m. and 3 p.m., 40 dr. Again sound sleep in n.; dreams of cemeteries and funerals ; drowsy laziness, yawning, stretching, cross, ill humoured ; still like band round head ; pain of hairs' roots ; tenderness of vertex ; choking in throat and windpipe ; quivering in neck near larynx ; pain in l. lung less ; constipation.-25th. At 8 a.m. , 35 dr. At n. pretty sound sleep without dreams. The other symptoms continue. At 5.30 p.m., there occur, in addition, intoxicated vertigo with nausea till 9 p.m., and warm perspiration on the face, neck, and chest, with internal and external heat, regular pulse, and no thirst, for h.; vertigo and nausea unaltered by walking, sitting, lying, in open air or in room. At 6 p.m., stool, very hard, knotty, difficult, with cutting pain in anus and rectum ; after stool rumbling in

bowels, with sensation of deranged stomach, lasting 1th.; pain in 1. lung again felt, increased by coughing and sneezing. At 9 p.m. , a kind oftingling in feet as after a long walk ; at same time internal and external chilliness, with great weight in occiput and drawing in nape from above downwards ; at 10.30 p.m. in bed, which had been warmed, increased chilliness and chattering of teeth for about h.; then sound sleep with few, unremembered dreams ; pulse regular. -26th . At 9 a.m. , giddy weight in upper part of head, like band round head ; tenderness of vertex and of hair ; rheumatic drawing pain in nape, worse when turning head to r. or 1.; choking sensation in throat and larynx ; quivering in neck ; increased pain in 1. lung ; anorexia ; nausea with pasty taste ; tingling in feet continues ; chilliness or heat not noticeable ; at noon slight rheumatic pains in 1. hip and 1. knee for 5 h., and in r. elbow-joint until 10 p.m.; constipation ; at n. very quiet sleep without dreams.-27th. Giddy weight in head diminished, but feeling of band round head is still there ; moreover, sensitiveness of throat and lung are less ; rheumatism in nape scarcely observable. Gone are : rheumatism in hip, arm, and elbows, the nausea and bad taste ; the quivering in neck only occurs every 3 or 4 h.; stool at first rather hard, then passed more easily and without pain ; great thirst for cold water, which when slaked always returned.-28th. Symptoms of yesterday milder ; vertex, when touched, feels as if a wound was healing below it ; head still feels bound round, but with looser band ; hardly any pain in lung ; choking in throat less, but still there ; quivering in neck occurred only a few times during d. for an instant ; eruption on 1. hand gone ; bowels regular without effort, stool not hard ; sleep quiet, dreamless.-29th. In m. still some oppression of head, and in place of choking feeling, rough and scrapy feeling in throat ; no other symptoms observed ; great thirst for cold water ; mind freer, more cheerful, increased inclination for work. Addenda.-1 . During proving, mind and spirits were more passive, depressed. 2. Desire for cold water went off, and wish for warm drinks came on. 3. Pulse even in the febrile state was always normal. 4. No perceptible effect in urine and genitals . b. Before commencing the next proving, I observed myself attentively for more than a week, but noticed nothing peculiar that could be confounded with the symptoms caused by this medicine ; moreover, I have not reperused my former proving of this medicine, in order to protect myself against the influence of the imagination, and I believe I have recorded all that happened to mind and body truly and faithfully. Although several symptoms, especially the affections of the mind and spirits, were extremely disagreeable and troublesome, and though my body to this day feels the effect, still I made the proving with pleasure and enthusiasm. June 16th.* At 2 p.m., slight confusion of upper part of head ; at 5, pressing sensation in top of head ; scalp is tender and hot to touch, also heat in upper part of head ; after taking some mild beer, increased heat of head ; painful sensation in eyeballs on looking up ; no stool ; * The prover has omitted mention of doses taken during this proving. In all probability they were much as before.- Eds .

profound sleep without dreams.-17th. Diminished aching in head ; sore feeling of upper part of scalp, and heat is felt there ; aching extended into occipital protuberance ; shooting pain and heat in index and middle fingers, which had been sprained by a fall eight weeks before ; pain in eyeballs less felt to-day ; at noon, choking sensation in larynx and surrounding parts (as formerly after taking beer and cigars) ; tongue white, furred ; slight nausea without loss of appetite. At 6 p.m., drowsiness ; dimness of eyes ; after rubbing them a little, burning feeling in them, in lids and the surrounding parts.-18th . At 8 a.m., pressing sensation in vertex and occiput moderate ; scalp tender and hot ; drowsiness ; dimness of eyes ; burning in them and lids ; slight pain in eyeballs on moving them ; choking and pressing in larynx more felt ; shooting and heat in fingers continue ; tongue furred, white ; slight transient nausea ; diminished appetite. At 6 p.m., still giddy weight in forehead ; very sound sleep from 10 p.m. to 7 a.m., uninterrupted, dreamless.-19th. At 8 a.m., whole head heavy ; aching in forehead and temples extending to nape ; on moving eyes pain in eyeballs and feeling of sand in eyes ; drowsiness ; itching of borders of eyelids ; scalp painful and hot to feel ; on combing hair, roots of hair are painful ; on moving head neck is stiff on both sides, and painful on taking deep breath ; feeling in l. lung as if a wound was there ; frequent yawning, and thereupon pains in sternum just over scrobiculus cordis ; shooting in index and middle fingers as yesterday ; saliva viscid and slimy ; skin since commencement of proving dry ; no chilliness, rather warm ; difficulty of thinking ; inclined to anger and peevishness ; sound dreamless sleep.-20th . Almost all symptoms are in abeyance, those in head only are still perceptible, but milder ; there is, however, weariness, unstrung feeling and stretching in limbs ; yawning. At 1 p.m., irresistible sleep, which lasted uninterruptedly till 4.30; after that weariness still continues, and there is bruised feeling in all the limbs as after a long walk. At 6 p.m. , all head and throat symptoms return as yesterday at 8 a.m., only in slighter degree, but lung symptoms are not felt ; these symptoms last till n.; restless sleep with tossing about and unremembered dreams.- 21st. At 7 a.m., feeling as if I had not had sleep enough ; cross, peevish disposition ; dull weight in head ; incapacity for thought ; scalp pains on being touched, is hot; stiffness in nape worse when moving ; weariness less felt. At 4 p.m., symptoms of head and throat, as also choking feeling in larynx, worse ; 1. lung is again painful ; drawing pain from neck over r. shoulder into r. wrist, intermitting for a few m., then recurring, worse when using arms, especially when writing ; in e., weariness.- 22nd. In m., dull empty weight in head ; cross, peevish , taciturn disposition ; sensations in upper part of scalp, in nape and cervical vertebræ as yesterday, also choking feel in larynx ; lung pain quite gone ; rheumatic pain in upper r. side from neck to wrist no longer intermits, but lasts all d.; in e., early drowsiness ; sound sleep at n.- 23rd. At 2 a.m., painful sensation of interior of throat in neighbourhood of larynx, worse when swallowing food and drink, or even the saliva, it feels raw ; œsophagus feels swollen and constricted, at same time a gurgling choking, with scraping feeling in it. (In foriner days

I have frequently felt this after taking cold, especially in feet, for weeks at a time, often increased by drinking beer and smoking cigars ; but it often came on without assignable cause.) Cross, peevish humour, dull weight in head, sore and hot feeling in scalp, continue ; on the other hand, the rheumatism in r. side of neck, shoulder, arm, and wrist is scarcely felt ; lung is quite painless ; irregular sleep, with unremembered dreams.- 24th. Inflammation of throat to-day more painful ; swallowing food and drink more difficult than yesterday ; choking and scraping in throat worse ; tongue furred white ; little appetite ; insipid, nauseous taste ; at the same time, very cross, quarrelsome disposition ; feelings in head and scalp as yesterday ; rheumatism gone ; restless sleep, disturbed by sore-throat and inclination to cough . -25th. Throat and other symptoms precisely the same as yesterday ; pretty sound sleep, without dreams.-26th. Throat symptoms somewhat better ; throat still painful on swallowing, scraping and choking are still there ; tongue but slightly furred ; appetite and taste better ; head not so heavy as yesterday; feeling on scalp too is better ; no trace of rheumatism ; quiet, sound sleep, without dreams.-27th. Throat much better; swallowing no longer difficult, only choking and scraping are present in slight degree; tongue clean ; appetite and taste good ; head still somewhat heavy, with little discomfort on top of head ; sleep quiet and sound,no dreams. On account of urgent affairs calling me away I omitted the provings for some d. c. July 4th. In m., as though I had not slept ; still sleepy at 8 a.m.; slight confusion of head, worse towards e., with feeling as if there was a lump in brain ; cross, peevish humour. At 3.30 p.m., such an uncommon good appetite that I ate nearly twice as much as usual, and drank some glasses of beer ; sound sleep at n.-5th. At 7 a m. , still desire to sleep ; dull weight in head. At 4 p.m., weight in head extended over to r. side of head ; then rheumatic drawing goes into r. side of neck, shoulder, arm, and wrist, involving two sprained fingers ; rheumatic drawing is also felt in r. side of chest, its seat not seemingly in lung, but in flesh, as it is not aggravated by breathing. Here again occurred an interruption of several days' duration. d. 10th. At 4 p.m., dull weight in forehead ; noise in ears for h.; flying rheumatic shoots in l. upper arm for a few m.; then increased aching in forehead, extending r. and 1. towards temples, and about 6 p.m. involving occiput. At 10 p.m., hoarse roaring in ears like distant storm of wind ; aching in forehead extends to orbits, which pain as if raw, when eyes are moved ; restless, dreamful sleep.-11th . At 7 a.m., weight in head somewhat diminshed ; on the other hand, scalp on vertex is very tender ; on brushing hair, roots feel as if gathering ; in eyes, itching as if from taking too much spirits ; tongue furred, white ; insipid taste ; pain in r. middle finger (sprained one) ; sleep pretty tranquil, dreamless.-12th. At 7 a.m., aching weight of whole head as if tightly bound and pinched in ; stiff neck, most felt on turning head ; aching in eyes as from sand ; scalp still painful ; roots of hair as if gathering; peevish, irritable humour ; difficulty of thinking. At 9 p.m., noises in ears, like storm of wind, which continued in bed; deep sleep as if stupefied until 7 a.m.-13th. Head to-day some

what lighter, pressing feeling in it still there ; pain in orbits, especially on moving eyes, as if I had not slept enough ; stiffness in nape ; scalp and hair-roots as if gathering ; tongue but little furred ; appetite and taste good ; better humour than yesterday. At 2 p.m., weight in head increases, with feeling of undulation in brain and upper part of scalp. At 4, after taking some small beer, undulation and weight in forehead, extending over upper part of scalp and towards temples, is very painful and disagreeable. At 8 p.m., there comes on, besides, roaring in l. ear, like wind howling, till sleep came on, which it did late ; then undisturbed sound sleep till 7 a.m.-14th. In m., only aching pain in top of head, forehead, and temples (no undulation). Stiffness in nape ; pain in nape on turning head r. or 1.; tongue still furred, whitish ; taste and appetite good ; orbits painful, worse on moving eyes, and drowsy aching in them. In the e., early tired and sleepy after walking 2 h.; sound sleep without dreams.- 15th. In m., aching in forehead, worse on turning eyes ; at same time, pain in orbits, and aching in eyes, like sand ; stiffness in nape slight, but still perceptible ; tongue whitish, with normal taste. At 6 p.m. , aching in forehead diminished somewhat, when walking in open air ; at 8 p.m. it is again as before. Great weariness and uninterrupted sleep at n.- 16th. Aching in forehead less, also pain in orbits. Pain in eyes as from sand, together with tenderness of scalp and hair-roots, unaltered ; drowsy stretching, yawning ; tongue whitish ; taste and appetite good ; nape still stiff, almost worse than yesterday ; rheumatic drawing in r. shoulder to r. side of chest, also drawing in r. upper and fore arm to wrist, ceasing a few m., then recurring. At 4 a.m., slight rheumatic drawing comes on also in 1. upper and fore arm ; it only lasts a few m., and returns after long intervals ; quiet, sound sleep, without dreams.-17th. Head is pretty free, and dull aching is perceptible about middle of head. Feelings connected with the scalp and hair-roots, also rheumatism, are gone ; stiffness of neck is scarcely felt ; tongue bright red ; taste quite pure ; appetite very good ; cheerful, happy disposition; desire for work.- 18th . Weight in head quite gone, also stiffness of neck ; no other symptoms felt.-19th. Quite free from symptoms. Cheerful humour ; e. 21st. feeling comfortable of health At 5 p.m., top ofstrength andininward aching . head, extending to r. side of forehead and 1. side of occiput ; aching in eyes and orbits, worse on moving eyes, as if I had passed sleepless n. At 9 p.m., roaring in l. ear like wind ; at n., pretty good sleep, with dreams of falling and bloody wounds.- 22nd. In m., whole head as if bound with band, inwardly pressing heaviness. At II a.m.,undulating feeling in head ; anorexia ; nausea ; white furred tongue. At n., deep stupefied sleep.- 23rd. As if I had not slept enough ; all limbs as if bruised ; weight of whole head, with undulating feeling in it, worse on moving eyes ; pain in orbits, aching in eyeballs as from sand ; tongue white furred ; disagreeable taste ; little appetite ; rheumatic drawing from r. shoulder to upper arm ; sore pain in l. lung, worse on breathing deeply ; early drowsiness, sound sleep until 8 a.m.-24th. In m., as if I had not slept ; cross, irritable humour ; low spirits ; confusion of head, most on 1. side from forehead to occipital protuberance ; 1. side of neck stiff on

moving ; rheumatic drawing pain from 1. shoulder to upper and fore arm and wrist ; in l. lung feeling of an unhealed wound, especially when breathing deeply ; tongue furred white ; disagreeable taste ; no appetite. At noon, rheumatic drawing pain in r. shoulder, upper and fore arm, as far as wrist ; drawing in 1. side somewhat abated. At 4 p.m. , rheumatism at one time in r., in another in 1. side of upper part of body, alternately, till 10 p.m.; sound sleep.-25th. In m., drowsiness, as though he had not slept all n.; dizzy weight in head, undulation in it towards forehead ; tenderness of scalp ; painful hairroots ; stiffness of neck as if paralysed on turning head. Rheumatism in shoulders and arms not present to-day ; on the other hand, larynx feels swollen, with choking gurgling in it , nothing perceptible to external touch. L. lung as yesterday; tongue furred white ; taste disagreeble ; without appetite ; early fatigue, drowsiness ; restless sleep at n ., with great weariness.-26th. At 4 a.m., sound sleep first came on, lasting till 8 a.m.; bruised feeling of whole body as after walking for many h.; head still heavy, but weight fixed more in the middle of head, without undulation. Symptoms of neck, larynx, lung, scalp and hair-roots as yesterday ; tongue somewhat cleaner, also appetite and taste somewhat better than yesterday ; on the other hand, cross humour ; indisposition to work, especially to think deeply. Fell asleep late with great weariness.-27th. In m., great weariness, ill humour, laziness ; dull weight in middle of head ; aching in orbits and eyeballs, as from sand in eyes ; neck still painful on moving head, on both sides, as if paralysed ; choking in throat much better ; pain in lung as yesterday, also in scalp and hair-roots. At 10 a.m., rheumatic drawing in r. upper half of body, shoulders, upper and fore arm, and wrist ; humour as yesterday ; tongue clean ; appetite and taste good. At 4 p.m., after taking small beer, weight in head worse, and there occurs an undulation in it ; 1. lung also is painful ; rheumatism and other symptoms continue. Restless sleep, full of dreams.- 28th. In m., weariness and bruised feeling continue ; head heavy as if bound ; aching in orbits and feeling of sand in eyes. Pain in neck on moving it still there ; choking in throat gone, lung free ; rheumatism in shoulder quite gone. Sleep quiet and sound.-29th. In m., weariness and bruised feeling, especially in lower extremities, knee and ankle-joints ; trembling and fatigue of whole body, as after long walk. Head still heavy, but less so than yesterday ; pressing sensation quite gone ; better humour ; desire for work. Sound, quiet sleep.-30th . Great lassitude of body, as after severe disease;; lower extremities and joints tired and bruised as after a long walk ; in head some dull weight, nothing more. Sleep sound and tranquil.- 31st. Whole body still languid as yesterday ; unhealthy look, with deep-set eyes, surrounded by blue rings ; weariness of lower limbs ; head quite free ; no other symptoms. Cheerful, happy spirits ; appetite, and good taste of food ; has disinclination for movement. (Ibid. 37.) 21. Mrs. R- [no further particulars concerning her] took, on Jan. 25th , at 9 a.m., 10 dr. of Ist dil. About 10, dizziness in head ; painfulness of vertex on touching it ; shooting in 1. side of vertex, going off and recurring at short intervals ; frequent yawning, stretch

ing ; disinclination for work ; vertigo, as if she should fall forwards ; would like to lie down and shut her eyes, as if she was intoxicated with alcoholic drinks ; ears feel too full. At I p.m., shooting tearing here and there in head, all over it ; duration of symptoms until 10.30 p.m., then sound sleep and many dreams, which she cannot remember.- 26th. At 8 a.m., same symptoms, with exception of the tearing, which has gone off, continue ; and at 9 there occurs also nausea, no appetite for food ; and at 10.30, vomiting of potatoes eaten yesterday, with a sharp, sourish taste, and scraping in the throat. Neuralgia in face, coming on in consequence of a cold caught, cut short the proving. (Ibid., 70.) 22. TH. WISCH. I am 44 years old, short, delicate, pale, blue eyes, blond hair ; easily excited to anger, but easily appeased ; of sensitive disposition. I am more disposed to constipation than to diarrhea . Feb. 15th , 1862. At 5.45 a.m., took 100 dr. of the medicine [strength not mentioned.- EDS.) . At noon, confusion of head, especially in forehead ; in afternoon the headache went off; on the other hand, I had cough with constant tickling in larynx.-16th. No symptoms.- 17th. Discharge of blood during coitus. (It once occurred before, and lasted about four weeks. I took homœopathic remedies for it, and until to-day it never happened again.)-18th . At 5 a.m., I again took 100 dr., as I observed no symptoms on the 16th and 17th . This time I had no headache, but the irritation of the larynx causing cough, which became so bad in e. that tears ran out of my eyes.- 19th . Still cough, but not so frequent ; no cough at n., but very healthy sleep.-20th . About noon, headache in forehead ; towards e., with shoots on 1. side. Till 26th, no symptoms .- 27th. At 5a.m., I took 40 dr. No symptoms. Though several more doses were taken no effects were obtained. (Ibid., 70.) 23. Mrs. S-, æt. 39 ; temperament sanguine ; constitution weak ; muscular system inclining to thinness ; hair reddish brown ; has nursed five children, which always made her very weak and exhausted. Two years ago she suffered for fourteen months from the consequences of articular rheumatism, and in autumn, 1861 , for three weeks from expectoration of bloody mucus from the throat, without cough. Since then she has felt quite well, and careful observation does not enable her to notice any particular symptoms. a. April 26th, 1862. At 3 p.m., 10 dr. of tinct. in a cup of water ; of this she took the third part. Immediately, oppression of chest and stomach ; after I h., stool at unusual time ; hammering sensation in ears ; eructation and yawning. At 6.30 p.m., took another third. Immediately, oppression of chest and stomach for 10 m.; constant eructation and yawning ; slight headache and aching in eyes ; in 1 h., sensation of weakness in legs. At 10 p.m., the last third.-27th . Sound sleep in n.,with sweat towards m.; cheerful spirits ; good appetite ; discharge of much flatus. At 9 a.m., 3 dr. in water ; same at 12, 3, and 8 p.m. Cheerful spirits all d.; urging to urinate oftener than usual.-28th. At 6 a.m., 3 dr.; at 4.30 p.m., 5 dr.; in h ., shoots in r. side, 5 m. later in r. shoulder, also in r. meatus

auditorius ; aching in sacrum and abdomen. At 8.30 p.m., 5 dr. Immediately, oppression in stomach, yawning, and eructation ; shoots in r. shoulder ; drawing in teeth ; feeling of warmth in stomach ; cheerful spirits.-29th. At 8.30 a.m., 5 dr.; same at 2.30 p.m. Increased appetite ; cheerful spirits ; frequent discharge of flatus all d. -May 2nd. At 4 p.m.,8 dr. Oppression, with yawning and eructation, immediately after taking medicine, as before ; in h., shoots in r. shoulder ; twitching now and then in head, with headache ; jerks in teeth ; noise in ears.-3rd. At 10 a.m., 8 dr. Immediately, yawning and eructation ; discharge of flatus ; stool very hard and dark brown ; in 1 h . , alleviating gurgling in stomach, as if air-bubbles rose into it and burst.-4th. At 9 a.m., 8 dr. Cheerfulness ; increased appetite. -5th . About 5 p.m., 10 dr. The same.-6th. At 8 a.m. , 10 dr. Inward uneasiness. At 10.30 a.m., 10 dr. Precordial anxiety ; discharge of much flatus. At 1.30 p.m., 10 dr. Precordial anxiety ; in h., cutting in stomach ; constant yawning for 10 m.; jerking in sternum and r. shoulder. At 6 p.m., 10 dr. Trembling in limbs, with eructation and yawning ; in h., shooting in l. hand. In h. , shoots in 1. shoulder-joint ; 5 m. later, shoots in 1. hand ; ringing in l. ear. At 8 p.m., shooting boring in l. tibia ; both ears as if stopped up ; shooting between shoulders.-7th . At 7 a.m., 10 dr. Shooting pains everywhere in head and shoulders ; shoots in r. side behind ribs and in l. leg ; cheerfulness and increased appetite. At II a.m., 10 dr. Immediately, headache with shooting in ears and vertigo ; drowsiness ; stiffness in nape ; cutting in stomach.-8th. At 7 a.m. , 10 dr. Drowsiness ; weariness in legs ; watery stool. At 2.30 p.m., drowsiness, yawning, and eructation ; shooting in neck and r. shoulder ; vesicles here and there in mouth and lips ; shoots close under r. scapula.- 10th . At 7 a.m., 15 dr. Immediately, inward uneasiness ; shooting here and there in throat and head, soon passing off. At 2 p.m., 15 dr. Oppression and anxiety at stomach immediately ; shooting in chest, shoulders, and head ; on account of the catamenia left off the proving.- 16th. The shootings formerly mentioned have recurred every d. till now in head, chest, shoulders, &c.; to-day stitch in chest, with difficulty of breathing. b. 22nd. At 7 a.m., 20 dr. in water. Immediately, yawning and eructation ; in h., stitches under r. scapula ; languor of whole body, and restlessness ; dull pressure in vertex. At 1.30 p.m., 6 dr. Immediately, yawning and eructation ; stitches under 1. scapula. At 5 p.m., 10 dr. Immediately, yawning and eructation ; shooting pain in l. calf towards foot. At 6 p.m., 10 dr. Immediately, yawning and eructation; discharge of much flatus ; shoots in r. shoulder and r. side of occiput ; water runs from nose ; dazzling of eyes and dimness of vision ; shoots in 1. upper arm and cardiac region, with dry cough. At 7 p.m. , 10 dr. After h., shoots in r. shoulder up to neck ; pain in lumbar vertebræ . After 2 h., toothache in a r. upper tooth for h . -23rd. On account of some dull headache, took nothing ; shoots in head and thoulders ; frequent fits of coughing.-27th. At 8 a.m., 12 dr. After 5 m., yawning and eructation ; after 1 h. , stitches in border of 1. ribs; languor of all body; shooting in fourth and fifth r.

toes. At 10.30, 8 dr. Immediately, yawning and eructation ; after 10 m., shoots in r. side, behind ribs ; dim sight ; roaring in r. ear ; increased appetite. At 2 p.m., 10 dr. in water ; took half of it. Immediately, yawning and eructation ; after h., drawing all over body ; pressure in vertex ; heat in cheeks ; about 3 p.m.,great drowsiness, so that I could hardly keep awake. At 4.30, took remaining half. After 10 m., yawning and eructation ; aching pain in vertex ; stitches close under heart ; drawing in head, teeth, jaws and shoulders. -28th. In m., disgusting sweetish taste of blood, with blood-streaked mucus in throat, on account of which I took no medicine ; shooting in r. shoulder, also in l. c. June 19th. The taste of blood, and bloody mucous expectoration from throat, every m. until to-day ; 10 dr. in a cup of water, taken at three times-in m., noon, and e. In m., immediately after taking it, yawning and eructation ; pain in sternum just above scrobiculus ; redness and heat in cheeks. At 2 p.m., toothache in 1. side ; discharge of much flatus ; stitches just under r. scapula at every breath, lasting 10 m.; discharge of much flatus ; anxiety and sleeplessness. At 5 p.m., labour-like pains from lumbar vertebræ over hips down into abdomen for 1 h. At 8 p.m., immediately after taking medicine, yawning and eructation. -20th. Sound sleep all n., with sweat on waking, after manydreams ; sweetish taste of blood in m.; at same time I felt so disturbed and restless that I could take no medicine ; hawked up mucus streaked with blood ; palpitation of heart for an h . ; fatigue and weariness in legs ; falling out of hair ; heat and redness in face coming and going ; aching in vertex ; cross, sad, anxious humour, as if I had done something bad, that will allow me no rest ; stitches under 1. scapula ; much thirst ; dryness in throat ; constant shivering ; shooting pain in vesical region, with frequent calls to pass water.-25th . Till yesterday the above symptoms gradually declined. At 8 a.m., 3 dr. Immediately, violent stitch in the cardiac region, 6 times repeated ; violent palpitation of heart, with anxiety and restlessness. At 2 p.m., 3 dr. Immediately, 5 or 6 violent stitches in rapid succession in cardiac region, as in m.; at 4 p.m., heat and redness of face, and burning in eyelids, till about 8 p.m.; aching in vertex ; occasionally violent pains extending from vertex to nape, compelling me to raise shoulders involuntarily, shut eyes, and tread softly when walking ; no stool.-26th. At 8 a.m., 10 dr. at once. Soon afterwards, heat in face, and burning in red eyelids ; aching and drawing in head, like yesterday. At 5 p.m. , drawing pains from lumbar vertebræ over hips into abdomen as before.-27th. Stitches in vesical region,with frequent desire to pass water ; urine for 3 d. reddish, of sharp, sourish smell. -28th . At 8 a.m., 3 dr. in half a cupful of water ; a tablespoonful every 3 h. Yawning and eructation. At 9, burning in cheeks ; anxiety and restlessness ; heat in eyelids. At I p.m., stitches in vesical region ; at 2, dryness in throat, with thirst ; at 5, pressure in bladder, discharge of flatus ; from 6 to 7 p.m., periodical toothache ; at 8.30 p.m., dull shooting in cardiac region ; at 8.45, shooting pain in r. tibia, just above ankle ; at 9.15, again toothache.-29th. Sound sleep VOL.; II dry. lips in m.; heat in eyelids ; at 9 a.m., cold 8 finger-points

and feet. At 10, 5 dr. in a cup of water, a tablespoonful every 3 h .; at 2 p.m., stitches in r. side, just under mamma ; at 4 p.m. , the same, with empty eructation ; at 5, stitches went from r. side to cardiac region ; at 7, burning in cheeks and eyelids ; constant increased appetite.-30th. Took the medicine as yesterday. At 1 p.m., shooting in r. hough ; at 1.30, shooting in r. wrist ; at 2, shooting in r. hip ; at 3, toothache in lower teeth, 1. side ; at 4.30, shooting in r. hough ; from 5 till bedtime, swollen lips, skin of which peels off ; palpitation of heart.-July Ist. On awaking, burning of eyes and cheeks ; paralysed feeling in legs ; cold finger-points. At 9 a.m., to dr. in a cup of water ; a tablespoonful every 3 h. After 10 m., anxiety and trembling of hands ; at 9.45, trembling in knees ; at 10, urging to urinate ; at 10.30, shooting in r. wrist, afterwards in l. forearm towards wrist ; eructation. At 10.45, boring pain in r. knee and in front of ankle ; at noon, shooting in l. forearm, also from 1. ear to nape ; cough ; at every cough abdomen contracts painfully. At I p.m. , stitches close under heart ; at 2, stitches in r. forearm and heat in cheeks ; shooting pains felt sometimes in arms, sometimes in legs ; at 2.30, pain in lumbar vertebræ, over hips down into abdomen ; at 3.30, boring pain in r. ear ; eructation and yawning till bedtime ; stitches here and there in body.- 2nd. Confused dreams at n.; in m., stitches like yesterday, lasting all d., now in arms, now in legs.-3rd. At 8 a.m. , 5 dr. at once in water. In an h., heat in cheeks ; at 2 p.m., stitches just under mamma ; painful contraction of abdomen on coughing.-4th . At 8 a.m., 5 dr. at once ; this d. I experienced nothing but twitching now and then in various parts.-5th. In n. I dreamt of a great procession through the town with music, so distinct that I was awakened by the kettledrum. To-day I took none, owing to a visit intervening. Twitching in legs and arms.-6th. Took none. Drawing all over body ; eroding itching in legs, obliging me to scratch.-7th. Same sensations.-8th. At 10 a.m., took 10 dr. at once. In 5 m., eructation ; in 2 h., an unusual stool ; at 2 p.m., pricking in r. forearm ; at 5, pricking in region of liver ; at 9, heat in cheeks and burning in eyes.-9th. At to a.m., 10 dr. at once. Shortly after, flaccidity ; pricking in region of heart ; at noon, heat in cheeks ; continued falling off of hair ; at 8 p.m., pricking on ribs (r. side) .- 10th . At 10a.m., took 10 dr. at a time in water. At once eructation ; in 3 m., buzzing in ears ; twitching in eyelids ; palpitation of heart ; at 11 , burning in cheeks and ringing in ears. At 1 , took 10 dr. in water. Immediately, eructation and yawning for 10 m.; pricking in r. hip, and pain from r. upper arm on inner side, extending to fingers ; roaring in ears ; toothache, extending up towards eyes ; at 2.30, pricking in r. middle finger ; at 3.45, pricking in third r. toe ; continued pain in foot, close under r. inner ankle ; pain on inner side of r. upper arm, extending to lower arm, then on inner side of 1. lower arm ; pricking in 1. hip ; h. after, twitching in l. temple ; pricking in r. side on ribs, felt on drawing each breath ; pricking pain in l. knee. At 6 p.m., took 10 dr. At once, yawning and eructation ; twitching in arms and legs ; feeling ill all over.- 11th . On awaking out of confused dreams after sound sleep, with perspiration

and dry lips, abdomen distended ; scraping feel in throat. At 7 a.m., took to dr. in water. Inh., twitching on inner side of thigh, in feet, and whole back ; pricking in head, over 1. eye, with twitching of lids ; pricking between eyebrows towards r. eye, in1. temple, and over 1. ear ; weight in head, with pricking here and there. At 12.30, took 10 dr.; in h ., pricking in r. shoulder, and on fore side of r. upper arm ; at 1 , pressure on crown ; heat in cheeks ; pricking pain in 1. clavicle, then in r. lower arm and close under r. shoulder-blade ; pricking in r. eye ; at 1.30, pricking in back, and continued pricking boring pain in crown, with twitching of eyelids, and in l. clavicle ; yawning ; pricking in 1. lower arm over wrist ; yawning and eructation ; at 1.45, pricking in r. ear, extending up towards crown ; 1 h. after, in l . ear. About 3 p.m. menstruation commenced, 4 d. earlier and more copious than usual, an h. after an attack of vertigo and reeling had occurred ; twitching in limbs unabated ; twitching and pricking in 1. clavicle very painful.-12th. I took no more. Since I took medicine, the usual perspiration of my feet has ceased, and my feet have remained permanently dry ; the pricking and twitching, and also vertigo, go on as yesterday ; besides, I feel myself much excited.- 13th. Pricking in head on coughing.-14th. Pricking in r. arm, head, and hip; cough ; dryness of hands.-15th. As yesterday.- 16th. Ditto.-17th. Felt no symptoms.-18th. P.m., violent pain in head, clavicle, and limbs ; pricking pains between shoulders ; drawing in teeth ; twitching pricking in temples.-22nd. Pricking in r. chest, and on inner side of 1. upper arm.-24th. Drawing through upper incisors ; p.m., above 1. eyetooth, a swelling formed rapidly in gums, from which blood flowed, whereupon it disappeared.- 25th. Toothache at n. d. 28th. At 7 a.m., took 5 dr.; at 12.30, same. At once, shuddering; pricking in l. hip ; at 1.15, weight in head, lameness in legs ; at 4 p.m., pricking here and there in chest ; palpitation of heart ; at 4.30, pricking in scrob. cordis, then in back, then in l. and next in r. cheek-bone, towards temple ; at 5, pricking in r. wrist, then in r. foot -first on inner, then on outer ankle. At 5, continued yawning and eructation ; pricking in upper part of chest.-29th, 7 a.m., took 5 dr. At once, shivering ; in an h., pricking on inner side of r. thigh ; at 8.30, great anxiety and oppression. At 11.30, 5 dr. In 10 m., pricking on inner r. ankle ; anxiety and restlessness, with palpitation ; yawning and eructation. Between 2 and 3, pricking in r. wrist ; towards e. , pricking here and there in chest ; perspiration at n.- 30th. At 9 a.m., took 5 dr. In h., pricking in r. middle finger ; at 10, pressure in upper half of 1. thigh. At noon, 5 dr. At 2, pricking below inner r. ankle ; at 2.30, pricking and boring pain in 1. cheek-bone, alternating with pain in l. upper eye-tooth ; itching at tip of nose ; at 4, water flowed from nostrils. At 6, 5 dr. All e., pressure on crown, and pain in l. cheek-bone and 1. upper teeth .-31st. Dreamt that my husband and I were burying two men alive ; pricking as yesterday in cheek-bone on awaking. At 11, took 5 dr. At 12, pricking in l. foot and thigh, in r. thigh and foot ; at 3, pricking high up in sternum and 1. leg ; yawning and eructation. Aug. Ist. No symptoms.- 2nd, m., pricking close under 1. clavicle and in cheek-

bones.-3rd. Ditto.-4th. Twitching in 1. eyelids ; pricking in the inner r. ankle ; pricking and boring in the teeth. Next d. I had no striking symptoms. (Ibid., 70.) II. Poisonings. I had sent Mr. N- a bottle with about zxij of tinct. , he having, at my request, undertaken to prove the medicine on himself. He had given the bottle to his wife, remarking, by way of caution, that she must shut it up carefully, because it was poison. Various engagements prevented him from at once commencing the proving. This lady, generally calm and intelligent, 38 years old, mother of seven children, on Dec. 17th, 1862, after her husband had left the house in a rage owing to her reproaches, drank, in a fit of jealousy, every drop of the tinct., intending to commit suicide. Being informed of this, I received about four weeks afterwards (at my own request to Mr. N-) the symptoms which he had observed in his wife and had obtained from her, written out as follows :- During first 3 d., great excitement of mind, with quarrelsome and peevish humour. From 4th d., daily in forenoon and afternoon, violent burning in vagina, lasting each time a full h.; this till 18th d. From 8th d. after poisoning, constant pricking and burning, as if from grain of sand, in inner corner of 1. eye, which had not quite left her after 14 d. At commencement of pains, inner corner of eye was red and inflamed, with feeling of great heat there, and after 14 d. eye was still weak and watery. During this time she complained of pricking in 1. side when sitting, and was often sleepy ; at other times in constant excitement. Often, in e., violent palpitation, lasting some h. , which at other times commenced earlier after dancing. For several d. she complained of violent pricking in throat, as if from a fish-bone. With this came on, also, hoarseness with dry cough, which at times brought up lumps of mucus ; besides soreness in nose, and sometimes redness and flying heat in face. At various times, severe pain in crown and l. temple ; headache so serious as to deprive her of power of thinking. Ever since poisoning, thinking has been difficult to her, and she easily forgets what she is going to do or has done. On 18th d., after supper fit of chill and nausea ; great tightness of chest ; headache on crown and l. temple ; shortness of breath lasted an h. On next e., pain in head returned, with chill ; oppression and cramp of chest, with nausea. These sufferings continued till m.; at noon, after eating, sufferings returned, except chill, instead of which came inward heat, with internal burning between chest and shoulder-blades. On the following d., no more symptoms occurred. (Ibid., 100. )

Volume IV — Appendix

CHELIDONIUM. (See vol. W, p. 61.)

II. 24. The symptoms I experienced from frequent— about hourli —I dr. doses of the 3X dil. continued during 3 d. were : On whoS surface of face an agreeable visible glow of heat ; a transient cardii pain i sharp pain under sternum ; great anal flatulence every n. 0 lying down ; on getting into bed sharp spasm in chest, together wit oppression of breathing and much cardiac anxiety (have no organs disease) ; awful dreams; thighs itched; neuralgic pain in neck and ear ; back, in renal region, felt weak and painful ; sacrum painful whc in bed ; cold feeling in stomach after food. On 4th d. felt very queer pharyngeal angina ; pustule like an incipient boil on hip. 5(h much pain during previous n. in sacrum and rectum ; blood passed stool (never occurred before) ; spasm under sternum at n. agail (" AcRicoLA," in M. H. Rev.y xxxiii, 763.)