Kali (Hyper -) Manganicum
By Timothy F. Allen — The Encyclopedia of Pure Materia Medica
Permanganate of Potash, 2KMnO4.
Preparation , Triturations.
Authorities.
1 , Dr. H. C. Allen, Am. Hom. Obs., 3, p. 345, took 251 grains in ten days, as follows: 6 grains forenoon, 10 grains P.M., first day; 10 grains A.M., second day; 15 grains at 9.40 and 10 grains at 11.30 A.M., third day; 10 grains 2.30, 20 grains 6 P.M., and 20 grains 8.30 P.M., fourth day; 30 grains 7.35 A.M. and 11 A.M., eighth day; 30 grains 9 A.M., ninth day; 30 grains 10.30 A.M., tenth day; 30 grains at 2 P.M., eleventh day; 2 , partner of last took 51 grains in three days; 3 , some students took a less quantity.
HEAD
- Head feels full (one hour after second dose, fourth day), 1.
EYE
- Profuse lachrymation (fifteen minutes after first dose, third day), 1.
EAR
- Sharp, piercing pain extending from the throat to the left mastoid process of temporal bone, apparently along the course of the Eustachian tube (fifty minutes after first dose, third day), 1.
NOSE
- Thin discharge from the nares, which smarts and irritates the mucous membrane (eleventh day), 1.
- Sanious discharge from the nares, 1.
- Sanious discharge from the nose; nares feel stuffed and full, as in catarrh; the discharge is blood-streaked, although I had no catarrhal symptoms (two hours and a half before), (one hour after second dose, third day), 1.
- Discharge from the nares and larynx streaked with blood (third day), 1.
- Nasal hæmorrhage (half an hour after second dose, eighth day), 1.
- Slight hæmorrhage from the nose (one hour after second dose, fourth day), 1. [10.]
- Profuse hæmorrhage from the nose (half an hour after third dose, fourth day); not so profuse (half an hour later), 1.
- Nose feels stuffed and full, and hæmorrhage sets in on every attempt to free the obstruction (eleventh day), 1.
MOUTH
- Mouth and lips very dry, the latter smart when exposed to the cold air (nine hours and a half after second dose, third day), 1.
- Increase of flow of saliva, which runs out of the mouth almost constantly, with more pain and difficulty of deglutition than ever (half an hour after second dose, eighth day), 1.
- Profuse flow of saliva, with a burning, raw, smarting, nauseating pain in the fauces, pharynx, larynx, and extending down the œsophagus to the stomach (half an hour after third dose, fourth day), 1.
- During the last hour a profuse flow of saliva from the mouth (so much so as to attract my attention, although I have had more or less all day, but I was not sure it was caused by the drug), with the same constant inclination to swallow manifested after each dose of the drug, but has now become very painful (two hours and a half after first dose, fourth day), 1.
- Profuse discharge of saliva (after half an hour, eleventh day), 1.
- Profuse salivation, 1.
- Speech painful and difficult; hoarse, as though I had tonsillitis (half an hour after third dose, fourth day), 1.
THROAT
- Objective.
- The throat was primarily affected, 3. [20.]
- Throat swollen and very painful (sixth day), 1.
- Small ulcerated spots here and there on the walls of the throat, with stinging, burning pains (tenth day), 1.
- Everything that is hawked up from the throat is streaked with blood (half an hour after third dose, fourth day), 1.
- Constant hawking up of a thick, blood-streaked, tenacious mucus, which appears to be abundant, but in reality is very little (two hours and a half after first dose, fourth day), 1.
- Subjective.
- Constant inclination to hawk up something, which is ineffectual (one hour and twenty minutes after first dose, third day), 1.
- Throat dry, painful, with incessant attempts at deglutition, from which it seems almost impossible to refrain (eighth day), 1.
- Throat very dry and raw (one hour after second dose, third day), 1.
- Continual dryness in the throat, with a slight, irritating, hacking cough on attempting to swallow (one hour and a quarter after second dose), 1.
- Raw dryness in the throat, and constant inclination to swallow, with the pain in the stomach (one hour and a half after first dose, fourth day), 1.
- The mucous membrane of the throat and larynx feels thick, and the larynx very painful (one hour and twenty minutes after first dose, third day), 1. [30.]
- The whole throat and larynx feel as though the cavity was constricted, apparently from thickening of the mucous membrane of fauces and larynx (one hour and three-quarters after second dose), 1.
- Peculiar constricting smarting sensation in the throat and fauces, with the hot burning sensation in the cardiac extremity of the stomach (twenty minutes after first dose), 1.
- Pain, heat, and dryness of the throat, with a constant desire to swallow, although deglutition was painful, 2.
- A great deal of pain in the throat all day, particularly on swallowing, for which there appears to be a constant desire (third day), 1.
- Increase of the same smarting, burning pain in the throat, extending along the œsophagus, attended with burning pain in the stomach (half an hour after first dose, fourth day), 1.
- Acute pain in the throat, extending to the ears and larynx, and producing a titillating cough (ninth day), .
STOMACH
- Appetite.
- Loss of appetite (second day), 1.
- Have been unable to eat for two days (sixth day), 1.
- Did not feel inclined to take any more of the drug (fifth day), 1.
- Thirst.
- Thirst, but inability to drink (fourth night), 1.
- Eructation. [60.]
- Almost constant flow of ropy mucus from the stomach, which is ejected without pain, but does not in the least relieve the nausea (one hour and a half after third dose, fourth day), 1.
- Nausea and Vomiting.
- Nausea, and constant inclination to swallow (fifteen minutes after first dose, third day), 1.
- Nauseating, sickening sensation at the stomach, soon (second day), 1.
- I could take no more of the drug, from a loathing which would almost produce vomiting to look at it (eleventh day), and although a month has elapsed since I took any of the drug, the simple taste, or even the sight of it, will produce nausea, 1.
- Nausea and vomiting (after half an hour, eleventh day), 1.
- Nausea and vomiting to such a degree that I began to search in vain for an antidote (twenty minutes after third dose, fourth day), 1.
- Nausea and vomiting, first of the contents of the stomach, afterwards of a thick ropy fluid, which is ejected in large quantities, but with very little difficulty, with more violent pain in the throat than hitherto (a quarter of an hour after second dose, fourth day), 1.
- The vomiting, which had ceased last evening, returned in an aggravated form, attended with a burning, nauseating pain in the stomach and duodenum, which became almost insupportable (ninth day), 1.
- Vomiting incessant, though painless (half an hour after third dose, fourth day), 1.
- Stomach.
- Deepseated, sickening pain in the stomach, with a raw dryness in the throat, and constant inclination to swallow (one hour and a half after first dose, fourth day), 1. [70.]
- Burning pain in the stomach (half an hour after first dose, fourth day), 1.
- Hot, burning pain in the stomach, which seems to radiate over the whole epigastrium (fifty-five minutes after second dose), .
STOOL
- Constipation (second day), 1.
- Obstinate constipation ever since I began to take the Permanganate (fifth day), 1.
URINARY ORGANS
- Compelled to urinate four or five times (an unusual circumstance with me); urine clear, watery, and in considerable quantities each time (fourth night), 1.
- Profuse discharge of urine (after half an hour, eleventh day), 1.
- Urine profuse (fifth day), 1.
- Urine more profuse than usual, and has to be voided more frequently (third day), 1.
- Urine very profuse and clear (thirty-five minutes after second dose); profuse and watery (one hour after second dose, fourth day), 1.
RESPIRATORY ORGANS
- Larynx. [80.]
- Aching pain in the region of the cricoid cartilage, aggravated by every attempt at deglutition (two hours and a half after first dose, fourth day), 1.
- Deepseated pain in lower part of the larynx, particularly in the region of the cricoid cartilage (one hour and three-quarters after second dose), 1.
- A sensation in hawking or clearing the larynx as though the surface was raw (third day), 1.
- Cough and Expectoration.
- Short hawking cough, with a constant, painful urging to swallow, which produced nausea and inclination to vomit, with profuse lachrymation (fifteen minutes after first dose, third day), 1.
- Constant, short painful hacking cough, and what little is hawked up is streaked with blood, as if the throat was raw (one hour after second dose, third day), 1.
- Coughing, or even hawking, brings up a sanious fluid (half an hour after second dose, eighth day); (after three hours, ninth day), 1.
HEART AND PULSE
- Pulse 80 at 2 A.M. (fifth day), 1.
- Pulse 92 (one hour after second dose, fourth day), 1.
- Pulse 94 (half an hour after third dose, fourth day), 1.
- Pulse 95 at 9 A.M. (eighth day), 1.
INFERIOR EXTREMITIES. [90.]
- The legs feel as though I could not move them, and tremble when I attempt to stand (eleventh day), 1.
GENERAL SYMPTOMS
- Felt weak, and unable to attend to any business (fifth day), 1.
- Weak, and very much prostrated (one hour after second dose, fourth day), 1.
- Terrible weakness and languor, particularly of the lower limbs, which compelled me to lie down (after half an hour, eleventh day), 1.